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Cheap flights from Louisville to San Diego from $124

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to San Diego departing on 11/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

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American Airlines Logo
1:32 pm - 10:26 pmSDF-SAN
11h 54m1 stop
American Airlines Logo
6:20 am - 11:19 pmSAN-SDF
13h 59m1 stop
$251American Airlines
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Tue, Jan 20 - Tue, Jan 27
United Airlines Logo
9:15 am - 4:36 pmSDF-SAN
10h 21m1 stop
United Airlines Logo
10:52 am - 8:28 pmSAN-SDF
6h 36m1 stop
$259United Airlines
Find Deal
Wed, Jan 28 - Wed, Feb 4
American Airlines Logo
1:32 pm - 10:26 pmSDF-SAN
11h 54m1 stop
American Airlines Logo
6:20 am - 11:19 pmSAN-SDF
13h 59m1 stop
$263American Airlines
Find Deal
Tue, Jan 6 - Tue, Jan 13
United Airlines Logo
9:50 am - 3:40 pmSDF-SAN
8h 50m1 stop
United Airlines Logo
11:08 am - 10:44 pmSAN-SDF
8h 36m2 stops
$264United Airlines
Find Deal
Wed, Jan 28 - Wed, Feb 4
Southwest Logo
6:00 am - 12:25 pmSDF-SAN
9h 25m2 stops
Southwest Logo
9:40 am - 9:10 pmSAN-SDF
8h 30m2 stops
$269Southwest
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Wed, Jan 28 - Wed, Feb 4
American Airlines Logo
1:15 pm - 8:36 pmSDF-SAN
10h 21m1 stop
American Airlines Logo
6:20 am - 5:33 pmSAN-SDF
8h 13m1 stop
$280American Airlines
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Thu, Jan 15 - Sun, Jan 18
American Airlines Logo
1:32 pm - 10:26 pmSDF-SAN
11h 54m1 stop
American Airlines Logo
6:15 am - 5:33 pmSAN-SDF
8h 18m2 stops
$285American Airlines
Find Deal
Tue, Jan 20 - Tue, Jan 27
American Airlines Logo
7:40 am - 2:14 pmSDF-SAN
9h 34m1 stop
American Airlines Logo
6:20 am - 11:19 pmSAN-SDF
13h 59m1 stop
$288American Airlines
Find Deal
Wed, Jan 28 - Sat, Jan 31
United Airlines Logo
5:35 am - 11:38 amSDF-SAN
9h 03m1 stop
United Airlines Logo
11:05 am - 10:37 pmSAN-SDF
8h 32m2 stops
$289United Airlines
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Tue, Feb 17 - Tue, Feb 24
American Airlines Logo
1:32 pm - 10:26 pmSDF-SAN
11h 54m1 stop
American Airlines Logo
6:20 am - 11:19 pmSAN-SDF
13h 59m1 stop
$290American Airlines
Find Deal
Wed, Jan 28 - Sat, Jan 31

American Airlines flights from Louisville to San Diego

Our best American Airlines deals on Louisville to San Diego flight tickets
American Airlines
Jan 20
SDF1:32 pmLouisville Intl
11h 54m
1 stop
SAN10:26 pmSan Diego
Jan 27
SAN6:20 amSan Diego
13h 59m
1 stop
SDF11:19 pmLouisville Intl
$251
Find similar
American Airlines
Jan 6
SDF1:32 pmLouisville Intl
11h 54m
1 stop
SAN10:26 pmSan Diego
Jan 13
SAN6:20 amSan Diego
13h 59m
1 stop
SDF11:19 pmLouisville Intl
$263
Find similar
American Airlines
Jan 15
SDF1:15 pmLouisville Intl
10h 21m
1 stop
SAN8:36 pmSan Diego
Jan 18
SAN6:20 amSan Diego
8h 13m
1 stop
SDF5:33 pmLouisville Intl
$280
Find similar

Delta flights from Louisville to San Diego

Our best Delta deals on Louisville to San Diego flight tickets
Delta
Jan 17
SDF12:22 pmLouisville Intl
10h 19m
1 stop
SAN7:41 pmSan Diego
Jan 28
SAN10:00 pmSan Diego
9h 01m
1 stop
SDF10:01 amLouisville Intl
$299
Find similar
Delta
Jan 28
SDF6:23 amLouisville Intl
7h 25m
1 stop
SAN10:48 amSan Diego
Jan 31
SAN2:20 pmSan Diego
6h 30m
1 stop
SDF11:50 pmLouisville Intl
$313
Find similar
Delta
Jan 17
SDF3:37 pmLouisville Intl
7h 04m
1 stop
SAN7:41 pmSan Diego
Jan 26
SAN10:00 pmSan Diego
9h 01m
1 stop
SDF10:01 amLouisville Intl
$318
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Louisville to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 1/20

1:32 pm-10:26 pm

1 stop11h 54m

San Diego

Tue 1/27

6:20 am-11:19 pm

1 stop13h 59m

$251

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 1/28

9:15 am-4:36 pm

1 stop10h 21m

San Diego

Wed 2/4

10:52 am-8:28 pm

1 stop6h 36m

$259

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 1/6

1:32 pm-10:26 pm

1 stop11h 54m

San Diego

Tue 1/13

6:20 am-11:19 pm

1 stop13h 59m

$263

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 1/28

9:50 am-3:40 pm

1 stop8h 50m

San Diego

Wed 2/4

11:08 am-10:44 pm

2 stops8h 36m

$264

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 1/28

6:00 am-12:25 pm

2 stops9h 25m

San Diego

Wed 2/4

9:40 am-9:10 pm

2 stops8h 30m

$269

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Thu 1/15

1:15 pm-8:36 pm

1 stop10h 21m

San Diego

Sun 1/18

6:20 am-5:33 pm

1 stop8h 13m

$280

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 1/20

1:32 pm-10:26 pm

1 stop11h 54m

San Diego

Tue 1/27

6:15 am-5:33 pm

2 stops8h 18m

$285

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 1/28

7:40 am-2:14 pm

1 stop9h 34m

San Diego

Sat 1/31

6:20 am-11:19 pm

1 stop13h 59m

$288

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 2/17

5:35 am-11:38 am

1 stop9h 03m

San Diego

Tue 2/24

11:05 am-10:37 pm

2 stops8h 32m

$289

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 1/28

1:32 pm-10:26 pm

1 stop11h 54m

San Diego

Sat 1/31

6:20 am-11:19 pm

1 stop13h 59m

$290

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Louisville to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of August, then departing from Louisville during the month September is also very affordable. Most momondo users find prices during this month for around $384.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Louisville to San Diego is on a Wednesday. Travelers who choose to depart for San Diego on a Wednesday will often find tickets for as low as $416. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $505. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is in the evening when flights can be purchased for as low as $393. Flights at noon are often more expensive with an average ticket price of $520.

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $447 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Louisville for as low as $347 on momondo.

How have Louisville to San Diego flight prices changed over time?

As of November 2025, prices for Louisville to San Diego flights are approximately 129% more expensive when compared to flights at the same time last year.

When to book flights from Louisville to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to San Diego (SDF to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to San Diego

Direct flights

None
There are no direct flights from Louisville to San Diego. There are no popular flight routes from Louisville to San Diego.
Search flight deals

  • How far is Louisville Intl to San Diego by plane?

    The straight-line distance from Louisville Intl to San Diego is 1797.3 mi. Flights usually cover this in 6h 20m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Louisville Intl Airport to San Diego Airport?

    Prices for flights from Louisville Intl Airport to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Louisville Intl Airport to San Diego Airport?

  • How old do you have to be to fly from Louisville Intl Airport to San Diego Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Louisville to San Diego?

Best airlines flying from Louisville to San Diego

Compare and see reviews for airlines that fly from Louisville to San Diego with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $232Free CancellationRating
6.3
8,139 reviews
Search Spirit Airlines flights
United AirlinesPriceFrom $274Free CancellationRating
7.4
9,017 reviews
Search United Airlines flights
DeltaPriceFrom $276Free CancellationRating
7.9
8,007 reviews
Search Delta flights
American AirlinesPriceFrom $303Free CancellationRating
7.2
11,051 reviews
Search American Airlines flights
SouthwestPriceFrom $362Free CancellationRating
8.0
4,242 reviews
Search Southwest flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
Imperial Beach
La Mesa
Poway
Borrego Springs
San Ysidro
Lemon Grove
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Louisville to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Louisville to San Diego with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Diego from Louisville with this policy.

How can momondo help me find flights from Louisville to San Diego?

momondo helps you find the best flight between Louisville and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Louisville to San Diego right now. Can momondo alert me if prices change?

Price alerts on flights to San Diego from Louisville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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