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Cheap flights from Louisville to San Diego from $125

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to San Diego departing on 3/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Louisville to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
1:32 pm - 10:26 pm
SDF
-
SAN
11h 54m1 stop
American Airlines Logo
10:35 pm - 11:30 am
SAN
-
SDF
9h 55m1 stop
$279American Airlines
Wed, Feb 11 - Tue, Feb 24
American Airlines Logo
12:07 pm - 8:20 pm
SDF
-
SAN
11h 13m1 stop
American Airlines Logo
10:35 pm - 11:30 am
SAN
-
SDF
9h 55m1 stop
$289American Airlines
Tue, Feb 24 - Mon, Mar 2
American Airlines Logo
1:32 pm - 10:26 pm
SDF
-
SAN
11h 54m1 stop
American Airlines Logo
2:46 pm - 12:13 am
SAN
-
SDF
6h 27m1 stop
$290American Airlines
Wed, Feb 11 - Sat, Feb 14
American Airlines Logo
1:32 pm - 10:26 pm
SDF
-
SAN
11h 54m1 stop
American Airlines Logo
6:20 am - 11:19 pm
SAN
-
SDF
13h 59m1 stop
$298American Airlines
Wed, Jan 28 - Sat, Jan 31
American Airlines Logo
1:32 pm - 10:26 pm
SDF
-
SAN
11h 54m1 stop
American Airlines Logo
6:15 am - 5:33 pm
SAN
-
SDF
8h 18m2 stops
$303American Airlines
Wed, Jan 28 - Sat, Jan 31
United Airlines Logo
9:00 am - 12:59 pm
SDF
-
SAN
6h 59m1 stop
United Airlines Logo
8:00 am - 8:28 pm
SAN
-
SDF
9h 28m2 stops
$314United Airlines
Sun, Jan 18 - Tue, Jan 27
American Airlines Logo
6:00 am - 11:39 am
SDF
-
SAN
8h 39m1 stop
American Airlines Logo
6:15 am - 7:03 pm
SAN
-
SDF
9h 48m1 stop
$317American Airlines
Sun, Feb 8 - Sat, Feb 21
American Airlines Logo
8:07 am - 10:26 pm
SDF
-
SAN
17h 19m1 stop
American Airlines Logo
6:15 am - 5:33 pm
SAN
-
SDF
8h 18m2 stops
$322American Airlines
Sat, Jan 24 - Sat, Jan 31
American Airlines Logo
1:32 pm - 10:26 pm
SDF
-
SAN
11h 54m1 stop
American Airlines Logo
10:09 am - 8:47 pm
SAN
-
SDF
7h 38m2 stops
$324American Airlines
Wed, Jan 28 - Sat, Jan 31
United Airlines Logo
3:30 pm - 9:56 pm
SDF
-
SAN
9h 26m1 stop
United Airlines Logo
12:11 pm - 9:59 pm
SAN
-
SDF
6h 48m1 stop
$327United Airlines
Mon, Jan 26 - Mon, Feb 2

American Airlines flights from Louisville to San Diego

Our best American Airlines deals on Louisville to San Diego flight tickets
American Airlines
Feb 11
SDF1:32 pmLouisville Intl
11h 54m
1 stop
SAN10:26 pmSan Diego
Feb 24
SAN10:35 pmSan Diego
9h 55m
1 stop
SDF11:30 amLouisville Intl
$279
Find similar
American Airlines
Feb 24
SDF12:07 pmLouisville Intl
11h 13m
1 stop
SAN8:20 pmSan Diego
Mar 2
SAN10:35 pmSan Diego
9h 55m
1 stop
SDF11:30 amLouisville Intl
$289
Find similar
American Airlines
Feb 11
SDF1:32 pmLouisville Intl
11h 54m
1 stop
SAN10:26 pmSan Diego
Feb 14
SAN2:46 pmSan Diego
6h 27m
1 stop
SDF12:13 amLouisville Intl
$290
Find similar

Delta flights from Louisville to San Diego

Our best Delta deals on Louisville to San Diego flight tickets
Delta
Feb 11
SDF3:32 pmLouisville Intl
8h 05m
1 stop
SAN8:37 pmSan Diego
Feb 14
SAN6:45 pmSan Diego
12h 19m
2 stops
SDF10:04 amLouisville Intl
$380
Find similar
Delta
Feb 11
SDF5:35 amLouisville Intl
7h 23m
1 stop
SAN9:58 amSan Diego
Feb 24
SAN7:20 amSan Diego
12h 45m
2 stops
SDF11:05 pmLouisville Intl
$395
Find similar
Delta
Jan 28
SDF6:23 amLouisville Intl
14h 37m
2 stops
SAN6:00 pmSan Diego
Jan 31
SAN5:35 pmSan Diego
13h 26m
2 stops
SDF10:01 amLouisville Intl
$415
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 30, 2025.
Use the filters below to find and compare flights from Louisville to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 2/11

1:32 pm-10:26 pm

1 stop11h 54m

San Diego

Tue 2/24

10:35 pm-11:30 am

1 stop9h 55m

$279

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 2/24

12:07 pm-8:20 pm

1 stop11h 13m

San Diego

Mon 3/2

10:35 pm-11:30 am

1 stop9h 55m

$289

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 2/11

1:32 pm-10:26 pm

1 stop11h 54m

San Diego

Sat 2/14

2:46 pm-12:13 am

1 stop6h 27m

$290

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 1/28

1:32 pm-10:26 pm

1 stop11h 54m

San Diego

Sat 1/31

6:20 am-11:19 pm

1 stop13h 59m

$298

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 1/28

1:32 pm-10:26 pm

1 stop11h 54m

San Diego

Sat 1/31

6:15 am-5:33 pm

2 stops8h 18m

$303

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Sun 1/18

9:00 am-12:59 pm

1 stop6h 59m

San Diego

Tue 1/27

8:00 am-8:28 pm

2 stops9h 28m

$314

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Sun 2/8

6:00 am-11:39 am

1 stop8h 39m

San Diego

Sat 2/21

6:15 am-7:03 pm

1 stop9h 48m

$317

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Sat 1/24

8:07 am-10:26 pm

1 stop17h 19m

San Diego

Sat 1/31

6:15 am-5:33 pm

2 stops8h 18m

$322

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 1/28

1:32 pm-10:26 pm

1 stop11h 54m

San Diego

Sat 1/31

10:09 am-8:47 pm

2 stops7h 38m

$324

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Mon 1/26

3:30 pm-9:56 pm

1 stop9h 26m

San Diego

Mon 2/2

12:11 pm-9:59 pm

1 stop6h 48m

$327

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Louisville to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of August, then departing from Louisville during the month September is also very affordable. Most momondo users find prices during this month for around $384.

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $442 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Louisville for as low as $347 on momondo.

How have Louisville to San Diego flight prices changed over time?

As of December 2025, prices for Louisville to San Diego flights are approximately 153% more expensive when compared to flights at the same time last year.

When to book flights from Louisville to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to San Diego (SDF to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to San Diego

Fastest flight time

6h 30m

Direct flights

None
The fastest flight from Louisville to San Diego takes 6h 30m
There are no direct flights from Louisville to San Diego. There are no popular flight routes from Louisville to San Diego.
Search flight deals

  • How far is Louisville Intl to San Diego by plane?

    The straight-line distance from Louisville Intl to San Diego is 1797.3 mi. Flights usually cover this in 6h 30m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Louisville Intl Airport to San Diego Airport?

    Prices for flights from Louisville Intl Airport to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Louisville Intl Airport to San Diego Airport?

  • How old do you have to be to fly from Louisville Intl Airport to San Diego Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Louisville to San Diego?

Best airlines flying from Louisville to San Diego

Compare and see reviews for airlines that fly from Louisville to San Diego with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $232Free CancellationRating
6.3
8,243 reviews
Search Spirit Airlines flights
United AirlinesPriceFrom $260Free CancellationRating
7.4
9,124 reviews
Search United Airlines flights
DeltaPriceFrom $276Free CancellationRating
7.9
8,013 reviews
Search Delta flights
American AirlinesPriceFrom $296Free CancellationRating
7.2
11,075 reviews
Search American Airlines flights
SouthwestPriceFrom $336Free CancellationRating
8.0
4,251 reviews
Search Southwest flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
Poway
National City
Imperial Beach
Borrego Springs
San Ysidro
La Mesa
Lemon Grove
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Louisville to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Louisville to San Diego with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Diego from Louisville with this policy.

How can momondo help me find flights from Louisville to San Diego?

momondo helps you find the best flight between Louisville and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Louisville to San Diego right now. Can momondo alert me if prices change?

Price alerts on flights to San Diego from Louisville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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