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Cheap flights from Louisville to San Diego from $121

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to San Diego departing on 2/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Louisville to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
4:30 pm - 11:05 pm
SDF
-
SAN
9h 35m
1 stop
Southwest Logo
6:20 am - 6:00 pm
SAN
-
SDF
8h 40m
1 stop
$321Southwest
Wed, Mar 25 - Wed, Apr 1
American Airlines Logo
6:00 am - 10:00 am
SDF
-
SAN
7h 00m
1 stop
American Airlines Logo
10:35 pm - 11:30 am
SAN
-
SDF
9h 55m
1 stop
$332American Airlines
Tue, Feb 24 - Mon, Mar 2
American Airlines Logo
6:12 pm - 10:34 pm
SDF
-
SAN
7h 22m
1 stop
American Airlines Logo
2:46 pm - 12:13 am
SAN
-
SDF
6h 27m
1 stop
$340American Airlines
Tue, Feb 24 - Sat, Feb 28
United Airlines Logo
3:15 pm - 8:51 pm
SDF
-
SAN
8h 36m
1 stop
United Airlines Logo
8:45 am - 8:14 pm
SAN
-
SDF
8h 29m
2 stops
$345United Airlines
Tue, Mar 3 - Sat, Mar 7
American Airlines Logo
6:00 am - 10:00 am
SDF
-
SAN
7h 00m
1 stop
American Airlines Logo
10:35 pm - 11:30 am
SAN
-
SDF
9h 55m
1 stop
$351American Airlines
Thu, Feb 26 - Mon, Mar 2
Delta Logo
10:50 am - 5:51 pm
SDF
-
SAN
10h 01m
1 stop
Delta Logo
2:18 pm - 11:57 pm
SAN
-
SDF
6h 39m
1 stop
$359Delta
Mon, Mar 30 - Sat, Apr 4
American Airlines Logo
6:23 pm - 10:23 pm
SDF
-
SAN
7h 00m
1 stop
American Airlines Logo
2:18 pm - 11:58 pm
SAN
-
SDF
6h 40m
1 stop
$363American Airlines
Sat, Mar 28 - Sat, Apr 4
United Airlines Logo
3:15 pm - 11:40 pm
SDF
-
SAN
11h 25m
2 stops
United Airlines Logo
12:55 pm - 9:59 pm
SAN
-
SDF
6h 04m
1 stop
$364United Airlines
Thu, Mar 5 - Sat, Mar 7
American Airlines Logo
3:33 pm - 9:07 pm
SDF
-
SAN
8h 34m
1 stop
American Airlines Logo
10:35 pm - 11:30 am
SAN
-
SDF
9h 55m
1 stop
$370American Airlines
Mon, Feb 23 - Sun, Mar 1
American Airlines Logo
6:23 pm - 11:59 pm
SDF
-
SAN
8h 36m
1 stop
American Airlines Logo
10:00 pm - 8:50 am
SAN
-
SDF
7h 50m
1 stop
$379American Airlines
Wed, Apr 1 - Sun, Apr 5

Southwest flights from Louisville to San Diego

Our best Southwest deals on Louisville to San Diego flight tickets
Southwest
Mar 25
SDF4:30 pmLouisville Intl
9h 35m
1 stop
SAN11:05 pmSan Diego
Apr 1
SAN6:20 amSan Diego
8h 40m
1 stop
SDF6:00 pmLouisville Intl
$321
Southwest
Mar 24
SDF5:00 pmLouisville Intl
8h 05m
1 stop
SAN10:05 pmSan Diego
Mar 29
SAN9:35 pmSan Diego
9h 20m
2 stops
SDF9:55 amLouisville Intl
$384
Southwest
Apr 22
SDF7:00 amLouisville Intl
8h 55m
2 stops
SAN12:55 pmSan Diego
Apr 27
SAN10:40 pmSan Diego
8h 10m
1 stop
SDF9:50 amLouisville Intl
$385

Delta flights from Louisville to San Diego

Our best Delta deals on Louisville to San Diego flight tickets
Delta
Mar 30
SDF10:50 amLouisville Intl
10h 01m
1 stop
SAN5:51 pmSan Diego
Apr 4
SAN2:18 pmSan Diego
6h 39m
1 stop
SDF11:57 pmLouisville Intl
$359
Delta
Apr 9
SDF5:35 pmLouisville Intl
8h 34m
1 stop
SAN11:09 pmSan Diego
Apr 16
SAN9:45 pmSan Diego
8h 07m
1 stop
SDF8:52 amLouisville Intl
$389
Delta
Mar 30
SDF10:50 amLouisville Intl
10h 01m
1 stop
SAN5:51 pmSan Diego
Apr 2
SAN10:30 pmSan Diego
7h 58m
1 stop
SDF9:28 amLouisville Intl
$398

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Louisville to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 3/25

4:30 pm-11:05 pm

1 stop9h 35m

San Diego

Wed 4/1

6:20 am-6:00 pm

1 stop8h 40m

$321

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 2/24

6:00 am-10:00 am

1 stop7h 00m

San Diego

Mon 3/2

10:35 pm-11:30 am

1 stop9h 55m

$332

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 2/24

6:12 pm-10:34 pm

1 stop7h 22m

San Diego

Sat 2/28

2:46 pm-12:13 am

1 stop6h 27m

$340

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 3/3

3:15 pm-8:51 pm

1 stop8h 36m

San Diego

Sat 3/7

8:45 am-8:14 pm

2 stops8h 29m

$345

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Thu 2/26

6:00 am-10:00 am

1 stop7h 00m

San Diego

Mon 3/2

10:35 pm-11:30 am

1 stop9h 55m

$351

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Mon 3/30

10:50 am-5:51 pm

1 stop10h 01m

San Diego

Sat 4/4

2:18 pm-11:57 pm

1 stop6h 39m

$359

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Sat 3/28

6:23 pm-10:23 pm

1 stop7h 00m

San Diego

Sat 4/4

2:18 pm-11:58 pm

1 stop6h 40m

$363

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Thu 3/5

3:15 pm-11:40 pm

2 stops11h 25m

San Diego

Sat 3/7

12:55 pm-9:59 pm

1 stop6h 04m

$364

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Mon 2/23

3:33 pm-9:07 pm

1 stop8h 34m

San Diego

Sun 3/1

10:35 pm-11:30 am

1 stop9h 55m

$370

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 4/1

6:23 pm-11:59 pm

1 stop8h 36m

San Diego

Sun 4/5

10:00 pm-8:50 am

1 stop7h 50m

$379

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Louisville to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of August, then departing from Louisville during the month September is also very affordable. Most momondo users find prices during this month for around $386.

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $431 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Louisville for as low as $347 on momondo.

How have Louisville to San Diego flight prices changed over time?

As of January 2026, prices for Louisville to San Diego flights are approximately 28% cheaper when compared to flights at the same time last year.

When to book flights from Louisville to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to San Diego (SDF to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to San Diego

Fastest flight time

6h 40m

Direct flights

None
The fastest flight from Louisville to San Diego takes 6h 40m
There are no direct flights from Louisville to San Diego. There are no popular flight routes from Louisville to San Diego.
Search flight deals

  • How far is Louisville Intl to San Diego by plane?

    The straight-line distance from Louisville Intl to San Diego is 1797.3 mi. Flights usually cover this in 6h 40m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Louisville Intl Airport to San Diego Airport?

    Prices for flights from Louisville Intl Airport to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Louisville Intl Airport to San Diego Airport?

  • How old do you have to be to fly from Louisville Intl Airport to San Diego Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Louisville to San Diego?

Best airlines flying from Louisville to San Diego

Compare and see reviews for airlines that fly from Louisville to San Diego with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $112Free CancellationRating
6.3
8,393 reviews
Search Spirit Airlines flights
DeltaPriceFrom $239Free CancellationRating
7.9
8,128 reviews
Search Delta flights
United AirlinesPriceFrom $260Free CancellationRating
7.4
9,215 reviews
Search United Airlines flights
American AirlinesPriceFrom $292Free CancellationRating
7.2
11,205 reviews
Search American Airlines flights
SouthwestPriceFrom $336Free CancellationRating
8.0
4,267 reviews
Search Southwest flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
Poway
National City
Imperial Beach
San Ysidro
Borrego Springs
La Mesa
Alpine
Lemon Grove
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Louisville to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Louisville to San Diego with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Diego from Louisville with this policy.

How can momondo help me find flights from Louisville to San Diego?

momondo helps you find the best flight between Louisville and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Louisville to San Diego right now. Can momondo alert me if prices change?

Price alerts on flights to San Diego from Louisville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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