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Cheap flights from Louisville to San Diego from $165

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to San Diego departing on 6/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Louisville to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:08 pm - 11:34 pm
SDF
-
SAN
7h 26m
1 stop
American Airlines Logo
11:00 pm - 9:01 am
SAN
-
SDF
7h 01m
1 stop
$329American Airlines
Tue, Sep 8 - Tue, Sep 15
Southwest Logo
11:50 am - 4:55 pm
SDF
-
SAN
8h 05m
2 stops
Southwest Logo
1:15 pm - 11:00 pm
SAN
-
SDF
6h 45m
1 stop
$334Southwest
Wed, Aug 26 - Wed, Sep 2
Delta Logo
6:00 am - 11:37 am
SDF
-
SAN
8h 37m
1 stop
Delta Logo
6:15 am - 4:46 pm
SAN
-
SDF
7h 31m
1 stop
$337Delta
Sat, Jun 13 - Sat, Jun 20
Southwest Logo
11:50 am - 4:55 pm
SDF
-
SAN
8h 05m
2 stops
Southwest Logo
8:15 am - 8:35 pm
SAN
-
SDF
9h 20m
2 stops
$339Southwest
Wed, Aug 26 - Wed, Sep 2
Southwest Logo
4:40 pm - 9:00 pm
SDF
-
SAN
7h 20m
1 stop
Southwest Logo
9:25 am - 9:55 pm
SAN
-
SDF
9h 30m
1 stop
$342Southwest
Sat, Oct 31 - Tue, Nov 3
Southwest Logo
9:20 am - 12:55 pm
SDF
-
SAN
6h 35m
1 stop
Southwest Logo
10:50 am - 10:45 pm
SAN
-
SDF
8h 55m
2 stops
$347Southwest
Sat, Oct 31 - Tue, Nov 3
Southwest Logo
9:55 am - 5:15 pm
SDF
-
SAN
10h 20m
1 stop
Southwest Logo
2:30 pm - 11:05 pm
SAN
-
SDF
5h 35m
1 stop
$350Southwest
Sat, Aug 15 - Thu, Aug 20
Southwest Logo
9:20 am - 2:50 pm
SDF
-
SAN
8h 30m
2 stops
Southwest Logo
12:45 pm - 10:45 pm
SAN
-
SDF
7h 00m
2 stops
$353Southwest
Sat, Oct 31 - Tue, Nov 3
American Airlines Logo
7:30 pm - 11:50 pm
SDF
-
SAN
7h 20m
1 stop
American Airlines Logo
11:48 am - 12:07 am
SAN
-
SDF
9h 19m
1 stop
$355American Airlines
Thu, Sep 3 - Thu, Sep 10
United Airlines Logo
1:50 pm - 7:55 pm
SDF
-
SAN
9h 05m
2 stops
United Airlines Logo
12:33 pm - 10:31 pm
SAN
-
SDF
6h 58m
1 stop
$360United Airlines
Sat, Aug 15 - Sat, Aug 22

United Airlines flights from Louisville to San Diego

Our best United Airlines deals on Louisville to San Diego flight tickets
United Airlines
Aug 15
SDF1:50 pmLouisville Intl
9h 05m
2 stops
SAN7:55 pmSan Diego
Aug 22
SAN12:33 pmSan Diego
6h 58m
1 stop
SDF10:31 pmLouisville Intl
$360
United Airlines
Aug 11
SDF3:25 pmLouisville Intl
8h 09m
1 stop
SAN8:34 pmSan Diego
Aug 12
SAN10:40 pmSan Diego
8h 02m
1 stop
SDF9:42 amLouisville Intl
$429
United Airlines
Sep 8
SDF5:15 amLouisville Intl
7h 17m
1 stop
SAN9:32 amSan Diego
Sep 15
SAN6:30 pmSan Diego
12h 27m
2 stops
SDF9:57 amLouisville Intl
$434

Southwest flights from Louisville to San Diego

Our best Southwest deals on Louisville to San Diego flight tickets
Southwest
Aug 26
SDF11:50 amLouisville Intl
8h 05m
2 stops
SAN4:55 pmSan Diego
Sep 2
SAN1:15 pmSan Diego
6h 45m
1 stop
SDF11:00 pmLouisville Intl
$334
Southwest
Aug 26
SDF11:50 amLouisville Intl
8h 05m
2 stops
SAN4:55 pmSan Diego
Sep 2
SAN8:15 amSan Diego
9h 20m
2 stops
SDF8:35 pmLouisville Intl
$339
Southwest
Oct 31
SDF4:40 pmLouisville Intl
7h 20m
1 stop
SAN9:00 pmSan Diego
Nov 3
SAN9:25 amSan Diego
9h 30m
1 stop
SDF9:55 pmLouisville Intl
$342

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 22, 2026.
Use the filters below to find and compare flights from Louisville to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 9/8

7:08 pm-11:34 pm

1 stop7h 26m

San Diego

Tue 9/15

11:00 pm-9:01 am

1 stop7h 01m

$329

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 8/26

11:50 am-4:55 pm

2 stops8h 05m

San Diego

Wed 9/2

1:15 pm-11:00 pm

1 stop6h 45m

$334

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Sat 6/13

6:00 am-11:37 am

1 stop8h 37m

San Diego

Sat 6/20

6:15 am-4:46 pm

1 stop7h 31m

$337

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 8/26

11:50 am-4:55 pm

2 stops8h 05m

San Diego

Wed 9/2

8:15 am-8:35 pm

2 stops9h 20m

$339

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Sat 10/31

4:40 pm-9:00 pm

1 stop7h 20m

San Diego

Tue 11/3

9:25 am-9:55 pm

1 stop9h 30m

$342

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Sat 10/31

9:20 am-12:55 pm

1 stop6h 35m

San Diego

Tue 11/3

10:50 am-10:45 pm

2 stops8h 55m

$347

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Sat 8/15

9:55 am-5:15 pm

1 stop10h 20m

San Diego

Thu 8/20

2:30 pm-11:05 pm

1 stop5h 35m

$350

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Sat 10/31

9:20 am-2:50 pm

2 stops8h 30m

San Diego

Tue 11/3

12:45 pm-10:45 pm

2 stops7h 00m

$353

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Thu 9/3

7:30 pm-11:50 pm

1 stop7h 20m

San Diego

Thu 9/10

11:48 am-12:07 am

1 stop9h 19m

$355

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Sat 8/15

1:50 pm-7:55 pm

2 stops9h 05m

San Diego

Sat 8/22

12:33 pm-10:31 pm

1 stop6h 58m

$360

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Louisville to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Louisville and San Diego?

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of August, then departing from Louisville during the month September is also very affordable. Most momondo users find prices during this month for around $381.

How far in advance should I book a flight from Louisville to San Diego?

You are more likely to see cheaper flights to San Diego from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $444 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Louisville for as low as $347 on momondo.

How have Louisville to San Diego flight prices changed over time?

As of May 2026, prices for Louisville to San Diego flights are approximately 72% more expensive when compared to flights at the same time last year.

When to book flights from Louisville to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to San Diego (SDF to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to San Diego

Fastest flight time

6h 38m

Direct flights

None
The fastest flight from Louisville to San Diego takes 6h 38m
There are no direct flights from Louisville to San Diego. There are no popular flight routes from Louisville to San Diego.
Search flight deals

Frequently asked questions about flying from Louisville to San Diego

  • How far is Louisville Intl to San Diego by plane?

    The straight-line distance from Louisville Intl to San Diego is 1797.3 mi. Flights usually cover this in 6h 38m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Louisville Intl Airport to San Diego Airport?

    Prices for flights from Louisville Intl Airport to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Louisville Intl Airport to San Diego Airport?

  • How old do you have to be to fly from Louisville Intl Airport to San Diego Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Louisville to San Diego?

Best airlines flying from Louisville to San Diego

Compare and see reviews for airlines that fly from Louisville to San Diego with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $260Free CancellationRating
7.4
9,751 reviews
Search United Airlines flights
DeltaPriceFrom $276Free CancellationRating
7.9
8,449 reviews
Search Delta flights
American AirlinesPriceFrom $282Free CancellationRating
7.1
11,644 reviews
Search American Airlines flights
SouthwestPriceFrom $323Free CancellationRating
7.9
4,278 reviews
Search Southwest flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
Poway
San Ysidro
La Mesa
Borrego Springs
Lemon Grove
Imperial Beach
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Louisville to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Louisville to San Diego with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Diego from Louisville with this policy.

How can momondo help me find flights from Louisville to San Diego?

momondo helps you find the best flight between Louisville and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Louisville to San Diego right now. Can momondo alert me if prices change?

Price alerts on flights to San Diego from Louisville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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