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Cheap flights from Louisville to San Diego from $113

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to San Diego departing on 2/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Louisville to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
2:35 pm - 8:46 pm
SDF
-
SAN
9h 11m1 stop
United Airlines Logo
10:30 am - 9:46 pm
SAN
-
SDF
8h 16m1 stop
$255United Airlines
Tue, Feb 24 - Tue, Mar 3
United Airlines Logo
9:00 am - 3:00 pm
SDF
-
SAN
9h 00m2 stops
United Airlines Logo
8:30 am - 7:42 pm
SAN
-
SDF
8h 12m1 stop
$260United Airlines
Tue, Feb 24 - Tue, Mar 3
United Airlines Logo
9:00 am - 3:00 pm
SDF
-
SAN
9h 00m2 stops
United Airlines Logo
11:05 am - 10:37 pm
SAN
-
SDF
8h 32m2 stops
$266United Airlines
Tue, Feb 24 - Tue, Mar 3
Delta Logo
6:44 pm - 11:02 pm
SDF
-
SAN
7h 18m1 stop
Delta Logo
2:15 pm - 11:58 pm
SAN
-
SDF
6h 43m1 stop
$277Delta
Mon, Feb 23 - Wed, Mar 4
American Airlines Logo
6:00 am - 2:17 pm
SDF
-
SAN
11h 17m1 stop
American Airlines Logo
6:40 am - 5:56 pm
SAN
-
SDF
8h 16m1 stop
$296American Airlines
Sat, Apr 25 - Tue, Apr 28
American Airlines Logo
6:00 am - 11:33 am
SDF
-
SAN
8h 33m1 stop
American Airlines Logo
7:10 am - 5:33 pm
SAN
-
SDF
7h 23m1 stop
$311American Airlines
Wed, Jan 28 - Sat, Jan 31
Delta Logo
6:23 am - 2:29 pm
SDF
-
SAN
11h 06m2 stops
Delta Logo
10:20 pm - 9:28 am
SAN
-
SDF
8h 08m1 stop
$312Delta
Tue, Feb 24 - Mon, Mar 2
Delta Logo
4:30 pm - 8:53 pm
SDF
-
SAN
7h 23m1 stop
Delta Logo
5:00 pm - 11:27 am
SAN
-
SDF
15h 27m2 stops
$315Delta
Mon, Feb 23 - Mon, Mar 2
American Airlines Logo
11:14 am - 4:54 pm
SDF
-
SAN
8h 40m1 stop
American Airlines Logo
10:09 am - 8:47 pm
SAN
-
SDF
7h 38m2 stops
$316American Airlines
Wed, Jan 28 - Sat, Jan 31
Delta Logo
5:00 pm - 11:02 pm
SDF
-
SAN
9h 02m1 stop
Delta Logo
10:10 pm - 10:04 am
SAN
-
SDF
8h 54m1 stop
$322Delta
Sat, Feb 21 - Thu, Mar 5

Southwest flights from Louisville to San Diego

Our best Southwest deals on Louisville to San Diego flight tickets
Southwest
Mar 11
SDF1:30 pmLouisville Intl
9h 05m
2 stops
SAN7:35 pmSan Diego
Mar 18
SAN9:20 pmSan Diego
9h 35m
2 stops
SDF9:55 amLouisville Intl
$332
Southwest
Feb 5
SDF6:25 amLouisville Intl
9h 25m
2 stops
SAN12:50 pmSan Diego
Feb 7
SAN9:25 amSan Diego
9h 00m
2 stops
SDF9:25 pmLouisville Intl
$348
Southwest
Feb 15
SDF6:25 amLouisville Intl
9h 25m
2 stops
SAN12:50 pmSan Diego
Feb 25
SAN9:40 amSan Diego
8h 30m
2 stops
SDF9:10 pmLouisville Intl
$365

American Airlines flights from Louisville to San Diego

Our best American Airlines deals on Louisville to San Diego flight tickets
American Airlines
Apr 25
SDF6:00 amLouisville Intl
11h 17m
1 stop
SAN2:17 pmSan Diego
Apr 28
SAN6:40 amSan Diego
8h 16m
1 stop
SDF5:56 pmLouisville Intl
$296
American Airlines
Jan 28
SDF6:00 amLouisville Intl
8h 33m
1 stop
SAN11:33 amSan Diego
Jan 31
SAN7:10 amSan Diego
7h 23m
1 stop
SDF5:33 pmLouisville Intl
$311
American Airlines
Jan 28
SDF11:14 amLouisville Intl
8h 40m
1 stop
SAN4:54 pmSan Diego
Jan 31
SAN10:09 amSan Diego
7h 38m
2 stops
SDF8:47 pmLouisville Intl
$316

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 8, 2026.
Use the filters below to find and compare flights from Louisville to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 2/24

2:35 pm-8:46 pm

1 stop9h 11m

San Diego

Tue 3/3

10:30 am-9:46 pm

1 stop8h 16m

$255

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 2/24

9:00 am-3:00 pm

2 stops9h 00m

San Diego

Tue 3/3

8:30 am-7:42 pm

1 stop8h 12m

$260

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 2/24

9:00 am-3:00 pm

2 stops9h 00m

San Diego

Tue 3/3

11:05 am-10:37 pm

2 stops8h 32m

$266

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Mon 2/23

6:44 pm-11:02 pm

1 stop7h 18m

San Diego

Wed 3/4

2:15 pm-11:58 pm

1 stop6h 43m

$277

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Sat 4/25

6:00 am-2:17 pm

1 stop11h 17m

San Diego

Tue 4/28

6:40 am-5:56 pm

1 stop8h 16m

$296

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 1/28

6:00 am-11:33 am

1 stop8h 33m

San Diego

Sat 1/31

7:10 am-5:33 pm

1 stop7h 23m

$311

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 2/24

6:23 am-2:29 pm

2 stops11h 06m

San Diego

Mon 3/2

10:20 pm-9:28 am

1 stop8h 08m

$312

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Mon 2/23

4:30 pm-8:53 pm

1 stop7h 23m

San Diego

Mon 3/2

5:00 pm-11:27 am

2 stops15h 27m

$315

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 1/28

11:14 am-4:54 pm

1 stop8h 40m

San Diego

Sat 1/31

10:09 am-8:47 pm

2 stops7h 38m

$316

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Sat 2/21

5:00 pm-11:02 pm

1 stop9h 02m

San Diego

Thu 3/5

10:10 pm-10:04 am

1 stop8h 54m

$322

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Louisville to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of August, then departing from Louisville during the month September is also very affordable. Most momondo users find prices during this month for around $384.

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $431 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Louisville for as low as $347 on momondo.

How have Louisville to San Diego flight prices changed over time?

As of January 2026, prices for Louisville to San Diego flights are approximately 29% cheaper when compared to flights at the same time last year.

When to book flights from Louisville to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to San Diego (SDF to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to San Diego

Fastest flight time

6h 52m

Direct flights

None
The fastest flight from Louisville to San Diego takes 6h 52m
There are no direct flights from Louisville to San Diego. There are no popular flight routes from Louisville to San Diego.
Search flight deals

  • How far is Louisville Intl to San Diego by plane?

    The straight-line distance from Louisville Intl to San Diego is 1797.3 mi. Flights usually cover this in 6h 52m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Louisville Intl Airport to San Diego Airport?

    Prices for flights from Louisville Intl Airport to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Louisville Intl Airport to San Diego Airport?

  • How old do you have to be to fly from Louisville Intl Airport to San Diego Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Louisville to San Diego?

Best airlines flying from Louisville to San Diego

Compare and see reviews for airlines that fly from Louisville to San Diego with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $232Free CancellationRating
6.3
8,287 reviews
Search Spirit Airlines flights
United AirlinesPriceFrom $260Free CancellationRating
7.4
9,139 reviews
Search United Airlines flights
DeltaPriceFrom $276Free CancellationRating
7.9
8,025 reviews
Search Delta flights
American AirlinesPriceFrom $294Free CancellationRating
7.2
11,095 reviews
Search American Airlines flights
SouthwestPriceFrom $336Free CancellationRating
8.0
4,248 reviews
Search Southwest flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
Poway
National City
Imperial Beach
Borrego Springs
La Mesa
San Ysidro
Alpine
Lemon Grove
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Louisville to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Louisville to San Diego with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Diego from Louisville with this policy.

How can momondo help me find flights from Louisville to San Diego?

momondo helps you find the best flight between Louisville and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Louisville to San Diego right now. Can momondo alert me if prices change?

Price alerts on flights to San Diego from Louisville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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