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Cheap flights from Louisville to San Diego from $151

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to San Diego departing on 9/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Louisville to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
5:15 am - 9:32 am
SDF
-
SAN
7h 17m
1 stop
United Airlines Logo
10:30 pm - 9:37 am
SAN
-
SDF
8h 07m
1 stop
$307United Airlines
Thu, Sep 3 - Tue, Sep 8
Southwest Logo
1:15 pm - 6:55 pm
SDF
-
SAN
8h 40m
2 stops
Southwest Logo
7:25 am - 5:55 pm
SAN
-
SDF
7h 30m
1 stop
$312Southwest
Wed, Aug 19 - Tue, Aug 25
American Airlines Logo
7:50 pm - 11:59 pm
SDF
-
SAN
7h 09m
1 stop
American Airlines Logo
7:15 am - 6:58 pm
SAN
-
SDF
8h 43m
1 stop
$314American Airlines
Tue, Jul 28 - Tue, Aug 4
Southwest Logo
10:50 am - 3:55 pm
SDF
-
SAN
8h 05m
2 stops
Southwest Logo
9:35 am - 8:35 pm
SAN
-
SDF
8h 00m
2 stops
$317Southwest
Wed, Aug 19 - Tue, Aug 25
Delta Logo
12:40 pm - 4:16 pm
SDF
-
SAN
6h 36m
1 stop
Delta Logo
12:59 pm - 12:26 am
SAN
-
SDF
8h 27m
1 stop
$321Delta
Sat, Jul 25 - Wed, Jul 29
American Airlines Logo
3:58 pm - 8:08 pm
SDF
-
SAN
7h 10m
1 stop
American Airlines Logo
11:09 am - 11:06 pm
SAN
-
SDF
8h 57m
1 stop
$322American Airlines
Wed, Oct 21 - Mon, Oct 26
Southwest Logo
1:15 pm - 6:55 pm
SDF
-
SAN
8h 40m
2 stops
Southwest Logo
2:30 pm - 11:05 pm
SAN
-
SDF
5h 35m
1 stop
$323Southwest
Wed, Aug 12 - Thu, Aug 20
Southwest Logo
12:40 pm - 8:10 pm
SDF
-
SAN
10h 30m
1 stop
Southwest Logo
6:20 am - 5:15 pm
SAN
-
SDF
7h 55m
2 stops
$326Southwest
Tue, Jul 21 - Sat, Sep 5
Southwest Logo
3:20 pm - 9:55 pm
SDF
-
SAN
9h 35m
2 stops
Southwest Logo
7:25 am - 5:55 pm
SAN
-
SDF
7h 30m
1 stop
$327Southwest
Mon, Aug 10 - Wed, Aug 19
American Airlines Logo
7:30 pm - 11:59 pm
SDF
-
SAN
7h 29m
1 stop
American Airlines Logo
6:15 am - 6:00 pm
SAN
-
SDF
8h 45m
1 stop
$329American Airlines
Thu, Sep 3 - Tue, Sep 8

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United Airlines flights from Louisville to San Diego

Our best United Airlines deals on Louisville to San Diego flight tickets
United Airlines
Sep 3
SDF5:15 amLouisville Intl
7h 17m
1 stop
SAN9:32 amSan Diego
Sep 8
SAN10:30 pmSan Diego
8h 07m
1 stop
SDF9:37 amLouisville Intl
$307
United Airlines
Aug 25
SDF7:25 amLouisville Intl
8h 52m
1 stop
SAN1:17 pmSan Diego
Aug 26
SAN10:13 amSan Diego
6h 46m
1 stop
SDF7:59 pmLouisville Intl
$407
United Airlines
Sep 3
SDF9:00 amLouisville Intl
13h 55m
2 stops
SAN7:55 pmSan Diego
Sep 10
SAN9:45 pmSan Diego
9h 33m
1 stop
SDF10:18 amLouisville Intl
$412

Southwest flights from Louisville to San Diego

Our best Southwest deals on Louisville to San Diego flight tickets
Southwest
Aug 19
SDF1:15 pmLouisville Intl
8h 40m
2 stops
SAN6:55 pmSan Diego
Aug 25
SAN7:25 amSan Diego
7h 30m
1 stop
SDF5:55 pmLouisville Intl
$312
Southwest
Aug 19
SDF10:50 amLouisville Intl
8h 05m
2 stops
SAN3:55 pmSan Diego
Aug 25
SAN9:35 amSan Diego
8h 00m
2 stops
SDF8:35 pmLouisville Intl
$317
Southwest
Aug 12
SDF1:15 pmLouisville Intl
8h 40m
2 stops
SAN6:55 pmSan Diego
Aug 20
SAN2:30 pmSan Diego
5h 35m
1 stop
SDF11:05 pmLouisville Intl
$323

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 1, 2026.
Use the filters below to find and compare flights from Louisville to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Thu 9/3

5:15 am-9:32 am

1 stop7h 17m

San Diego

Tue 9/8

10:30 pm-9:37 am

1 stop8h 07m

$307

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 8/19

1:15 pm-6:55 pm

2 stops8h 40m

San Diego

Tue 8/25

7:25 am-5:55 pm

1 stop7h 30m

$312

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 7/28

7:50 pm-11:59 pm

1 stop7h 09m

San Diego

Tue 8/4

7:15 am-6:58 pm

1 stop8h 43m

$314

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 8/19

10:50 am-3:55 pm

2 stops8h 05m

San Diego

Tue 8/25

9:35 am-8:35 pm

2 stops8h 00m

$317

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Sat 7/25

12:40 pm-4:16 pm

1 stop6h 36m

San Diego

Wed 7/29

12:59 pm-12:26 am

1 stop8h 27m

$321

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 10/21

3:58 pm-8:08 pm

1 stop7h 10m

San Diego

Mon 10/26

11:09 am-11:06 pm

1 stop8h 57m

$322
Quickest round-trip

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 8/12

1:15 pm-6:55 pm

2 stops8h 40m

San Diego

Thu 8/20

2:30 pm-11:05 pm

1 stop5h 35m

$323

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 7/21

12:40 pm-8:10 pm

1 stop10h 30m

San Diego

Sat 9/5

6:20 am-5:15 pm

2 stops7h 55m

$326

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Mon 8/10

3:20 pm-9:55 pm

2 stops9h 35m

San Diego

Wed 8/19

7:25 am-5:55 pm

1 stop7h 30m

$327

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Thu 9/3

7:30 pm-11:59 pm

1 stop7h 29m

San Diego

Tue 9/8

6:15 am-6:00 pm

1 stop8h 45m

$329

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Louisville to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Louisville and San Diego?

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of August, then departing from Louisville during the month February is also very affordable. Most momondo users find prices during this month for around $378.

How far in advance should I book a flight from Louisville to San Diego?

You are more likely to see cheaper flights to San Diego from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $434 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Louisville for as low as $333 on momondo.

How have Louisville to San Diego flight prices changed over time?

As of July 2026, prices for Louisville to San Diego flights are approximately 14% more expensive when compared to flights at the same time last year.

When to book flights from Louisville to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to San Diego (SDF to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to San Diego

Fastest flight time

6h 25m

Direct flights

None
The fastest flight from Louisville to San Diego takes 6h 25m
There are no direct flights from Louisville to San Diego. There are no popular flight routes from Louisville to San Diego.
Search flight deals

Frequently asked questions about flying from Louisville to San Diego

  • How far is Louisville Intl to San Diego by plane?

    The straight-line distance from Louisville Intl to San Diego is 1797.3 mi. Flights usually cover this in 6h 25m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Louisville Intl Airport to San Diego Airport?

    Prices for flights from Louisville Intl Airport to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Louisville Intl Airport to San Diego Airport?

  • How old do you have to be to fly from Louisville Intl Airport to San Diego Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Louisville to San Diego?

Best airlines flying from Louisville to San Diego

Compare and see reviews for airlines that fly from Louisville to San Diego with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $260Free CancellationRating
7.4
9,909 reviews
Search United Airlines flights
DeltaPriceFrom $276Free CancellationRating
7.8
8,452 reviews
Search Delta flights
American AirlinesPriceFrom $281Free CancellationRating
7.1
11,766 reviews
Search American Airlines flights
SouthwestPriceFrom $332Free CancellationRating
7.9
4,246 reviews
Search Southwest flights

  • Southwest Flights From Louisville to San Diego

    Southwest is one of the most popular airlines flying from Louisville to San Diego, operating 2 flights/week on average for this route. A good Southwest flight deal for Louisville to San Diego starts from $332 round-trip, up to an average price of $465. Our users have rated Southwest at 7.9/10.

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Chula Vista
Coronado
El Cajon
Julian
National City
La Mesa
Poway
San Ysidro
Imperial Beach
Borrego Springs
Santee
Lemon Grove
Alpine

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Louisville to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Louisville to San Diego with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Diego from Louisville with this policy.

How can momondo help me find flights from Louisville to San Diego?

momondo helps you find the best flight between Louisville and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Louisville to San Diego right now. Can momondo alert me if prices change?

Price alerts on flights to San Diego from Louisville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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