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Cheap flights from Louisville to San Diego from $114

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to San Diego departing on 10/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Multiple Airlines Logo
2:57 pm - 11:04 pmSDF-SAN
11h 07m1 stop
Multiple Airlines Logo
4:06 pm - 2:02 pmSAN-SDF
18h 56m1 stop
$235Multiple Airlines
Find Deal
Fri, Oct 24 - Sun, Oct 26
American Airlines Logo
1:02 pm - 8:45 pmSDF-SAN
10h 43m1 stop
American Airlines Logo
6:15 am - 10:00 pmSAN-SDF
12h 45m1 stop
$239American Airlines
Find Deal
Wed, Dec 10 - Sat, Dec 13
Spirit Airlines Logo
10:14 am - 11:34 pmSDF-SAN
16h 20m2 stops
Spirit Airlines Logo
6:15 am - 3:20 pmSAN-SDF
6h 05m1 stop
$305Spirit Airlines
Find Deal
Tue, Sep 30 - Fri, Oct 3
United Airlines Logo
7:00 am - 11:31 amSDF-SAN
7h 31m1 stop
United Airlines Logo
9:00 am - 8:44 pmSAN-SDF
8h 44m2 stops
$322United Airlines
Find Deal
Tue, Oct 28 - Tue, Nov 4
Southwest Logo
11:55 am - 6:10 pmSDF-SAN
9h 15m2 stops
Southwest Logo
10:30 am - 9:30 pmSAN-SDF
8h 00m2 stops
$327Southwest
Find Deal
Tue, Oct 28 - Tue, Nov 4
Delta Logo
7:05 am - 1:03 pmSDF-SAN
8h 58m1 stop
Delta Logo
10:00 pm - 9:59 amSAN-SDF
8h 59m1 stop
$334Delta
Find Deal
Mon, Nov 24 - Wed, Dec 3
United Airlines Logo
9:00 am - 12:59 pmSDF-SAN
6h 59m1 stop
United Airlines Logo
9:00 am - 8:28 pmSAN-SDF
8h 28m2 stops
$335United Airlines
Find Deal
Sat, Jan 24 - Tue, Jan 27
Spirit Airlines Logo
8:23 am - 7:29 amSDF-SAN
26h 06m2 stops
Spirit Airlines Logo
6:15 am - 3:20 pmSAN-SDF
6h 05m1 stop
$336Spirit Airlines
Find Deal
Tue, Sep 30 - Fri, Oct 3
Southwest Logo
5:30 pm - 10:30 pmSDF-SAN
8h 00m1 stop
Southwest Logo
10:20 am - 9:30 pmSAN-SDF
8h 10m2 stops
$339Southwest
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Thu, Oct 30 - Wed, Nov 12
Delta Logo
7:15 pm - 11:27 pmSDF-SAN
7h 12m1 stop
Delta Logo
10:20 pm - 9:50 amSAN-SDF
8h 30m1 stop
$351Delta
Find Deal
Thu, Oct 16 - Sat, Oct 18

American Airlines flights from Louisville to San Diego

Our best American Airlines deals on Louisville to San Diego flight tickets
American Airlines
Dec 10
SDF1:02 pmLouisville Intl
10h 43m
1 stop
SAN8:45 pmSan Diego
Dec 13
SAN6:15 amSan Diego
12h 45m
1 stop
SDF10:00 pmLouisville Intl
$239
Find similar
American Airlines
Jan 24
SDF11:13 amLouisville Intl
11h 47m
1 stop
SAN8:00 pmSan Diego
Jan 27
SAN8:07 amSan Diego
6h 07m
1 stop
SDF5:14 pmLouisville Intl
$268
Find similar
American Airlines
Oct 28
SDF6:00 amLouisville Intl
6h 56m
1 stop
SAN9:56 amSan Diego
Nov 4
SAN6:19 amSan Diego
11h 00m
1 stop
SDF8:19 pmLouisville Intl
$278
Find similar

Spirit Airlines flights from Louisville to San Diego

Our best Spirit Airlines deals on Louisville to San Diego flight tickets
Spirit Airlines
Sep 30
SDF10:14 amLouisville Intl
16h 20m
2 stops
SAN11:34 pmSan Diego
Oct 3
SAN6:15 amSan Diego
6h 05m
1 stop
SDF3:20 pmLouisville Intl
$305
Find similar
Spirit Airlines
Sep 30
SDF8:23 amLouisville Intl
26h 06m
2 stops
SAN7:29 amSan Diego
Oct 3
SAN6:15 amSan Diego
6h 05m
1 stop
SDF3:20 pmLouisville Intl
$336
Find similar
Spirit Airlines
Sep 29
SDF4:20 pmLouisville Intl
9h 06m
1 stop
SAN10:26 pmSan Diego
Oct 3
SAN6:15 amSan Diego
6h 05m
1 stop
SDF3:20 pmLouisville Intl
$387
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Louisville to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Fri 10/24

2:57 pm-11:04 pm

1 stop11h 07m

San Diego

Sun 10/26

4:06 pm-2:02 pm

1 stop18h 56m

$235

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 12/10

1:02 pm-8:45 pm

1 stop10h 43m

San Diego

Sat 12/13

6:15 am-10:00 pm

1 stop12h 45m

$239

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 9/30

10:14 am-11:34 pm

2 stops16h 20m

San Diego

Fri 10/3

6:15 am-3:20 pm

1 stop6h 05m

$305

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 10/28

7:00 am-11:31 am

1 stop7h 31m

San Diego

Tue 11/4

9:00 am-8:44 pm

2 stops8h 44m

$322

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 10/28

11:55 am-6:10 pm

2 stops9h 15m

San Diego

Tue 11/4

10:30 am-9:30 pm

2 stops8h 00m

$327

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Mon 11/24

7:05 am-1:03 pm

1 stop8h 58m

San Diego

Wed 12/3

10:00 pm-9:59 am

1 stop8h 59m

$334

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Sat 1/24

9:00 am-12:59 pm

1 stop6h 59m

San Diego

Tue 1/27

9:00 am-8:28 pm

2 stops8h 28m

$335

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 9/30

8:23 am-7:29 am

2 stops26h 06m

San Diego

Fri 10/3

6:15 am-3:20 pm

1 stop6h 05m

$336

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Thu 10/30

5:30 pm-10:30 pm

1 stop8h 00m

San Diego

Wed 11/12

10:20 am-9:30 pm

2 stops8h 10m

$339

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Thu 10/16

7:15 pm-11:27 pm

1 stop7h 12m

San Diego

Sat 10/18

10:20 pm-9:50 am

1 stop8h 30m

$351

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Louisville to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of August, then departing from Louisville during the month September is also very affordable. Most momondo users find prices during this month for around $396.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Louisville to San Diego is on a Wednesday. Travelers who choose to depart for San Diego on a Wednesday will often find tickets for as low as $416. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $505. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is in the evening when flights can be purchased for as low as $393. Flights at noon are often more expensive with an average ticket price of $520.

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $446 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Louisville for as low as $364 on momondo.

How have Louisville to San Diego flight prices changed over time?

As of September 2025, prices for Louisville to San Diego flights are approximately 35% more expensive when compared to flights at the same time last year.

When to book flights from Louisville to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to San Diego (SDF to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to San Diego

Direct flights

None
There are no direct flights from Louisville to San Diego. There are no popular flight routes from Louisville to San Diego.
Search flight deals

  • How far is Louisville Intl to San Diego by plane?

    The straight-line distance from Louisville Intl to San Diego is 1797.3 mi. Flights usually cover this in 6h 31m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Louisville Intl Airport to San Diego Airport?

    Prices for flights from Louisville Intl Airport to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Louisville Intl Airport to San Diego Airport?

  • How old do you have to be to fly from Louisville Intl Airport to San Diego Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Louisville to San Diego?

Best airlines flying from Louisville to San Diego

Compare and see reviews for airlines that fly from Louisville to San Diego with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $232Free CancellationRating
6.3
8,023 reviews
Search Spirit Airlines flights
United AirlinesPriceFrom $274Free CancellationRating
7.4
8,926 reviews
Search United Airlines flights
DeltaPriceFrom $276Free CancellationRating
7.9
7,961 reviews
Search Delta flights
American AirlinesPriceFrom $307Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
SouthwestPriceFrom $346Free CancellationRating
8.0
4,242 reviews
Search Southwest flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
La Mesa
National City
Poway
Imperial Beach
San Ysidro
Borrego Springs
Lemon Grove
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Louisville to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Louisville to San Diego with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Diego from Louisville with this policy.

How can momondo help me find flights from Louisville to San Diego?

momondo helps you find the best flight between Louisville and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Louisville to San Diego right now. Can momondo alert me if prices change?

Price alerts on flights to San Diego from Louisville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your San Diego trip

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