What is the cheapest airline that flies from Louisville Intl to San Diego?

American Airlines, United Airlines, and Delta are the most popular carriers operating from Louisville Intl to San Diego

What airlines fly to San Diego?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to San Diego from Louisville according to our data. American Airlines is the first choice among our users, with 46% of people opting to fly with this airline when traveling to San Diego. Keep in mind that there are 7 different airlines that fly to San Diego on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Louisville Intl Airport to San Diego Airport?

Prices for flights from Louisville Intl Airport to San Diego Airport were last updated today.

How many operators does momondo search for flights from Louisville Intl Airport to San Diego Airport?

As of August 2026, there are 4 operators available to choose from for flights from Louisville Intl Airport to San Diego Airport.

How old do you have to be to fly from Louisville Intl Airport to San Diego Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to San Diego Airport.

What documentation or ID do you need to fly to San Diego Airport?

The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$161 Cheap Flights from Louisville to San Diego in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Louisville to San Diego

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

10:56 am - 11:51 pmSDF Louisville Intl-SAN San Diego

15h 55m2 stops Raleigh-Durham Denver Intl

1:22 pm - 10:11 amSAN San Diego-SDF Louisville Intl

17h 49m1 stop Raleigh-Durham

$303Multiple Airlines

Sat, Sep 12 - Tue, Sep 15

10:56 am - 11:51 pmSDF Louisville Intl-SAN San Diego

15h 55m2 stops Raleigh-Durham Denver Intl

1:22 pm - 10:11 amSAN San Diego-SDF Louisville Intl

17h 49m1 stop Raleigh-Durham

$304Multiple Airlines

Sat, Sep 12 - Tue, Sep 15

6:45 pm - 10:40 pmSDF Louisville Intl-SAN San Diego

6h 55m1 stop Chicago Midway

2:30 pm - 11:10 pmSAN San Diego-SDF Louisville Intl

5h 40m1 stop Phoenix Sky Harbor Intl

$316Southwest

Wed, Sep 9 - Thu, Sep 10

7:10 pm - 10:05 pmSDF Louisville Intl-SAN San Diego

5h 55m1 stop Phoenix Sky Harbor Intl

6:30 am - 3:15 pmSAN San Diego-SDF Louisville Intl

5h 45m1 stop Dallas Love Field

$316Southwest

Wed, Oct 14 - Wed, Oct 21

4:18 pm - 9:46 pmSDF Louisville Intl-SAN San Diego

8h 28m1 stop Dallas/Fort Worth

7:15 am - 6:37 pmSAN San Diego-SDF Louisville Intl

8h 22m1 stop Dallas/Fort Worth

$321American Airlines

Wed, Oct 21 - Mon, Oct 26

5:04 am - 9:10 amSDF Louisville Intl-SAN San Diego

7h 06m1 stop Charlotte Douglas

6:20 am - 6:37 pmSAN San Diego-SDF Louisville Intl

9h 17m1 stop Dallas/Fort Worth

$321American Airlines

Wed, Oct 14 - Sat, Oct 17

2:10 pm - 6:34 pmSDF Louisville Intl-SAN San Diego

7h 24m1 stop Chicago O'Hare Intl

12:45 pm - 9:57 pmSAN San Diego-SDF Louisville Intl

6h 12m1 stop Denver Intl

$321United Airlines

Mon, Nov 23 - Wed, Dec 2

5:15 am - 9:32 amSDF Louisville Intl-SAN San Diego

7h 17m1 stop Chicago O'Hare Intl

12:45 pm - 11:59 pmSAN San Diego-SDF Louisville Intl

8h 14m1 stop Washington, D.C. Dulles Intl

$321United Airlines

Wed, Sep 16 - Wed, Sep 23

4:29 pm - 8:37 pmSDF Louisville Intl-SAN San Diego

7h 08m1 stop Minneapolis St Paul

10:30 pm - 10:19 amSAN San Diego-SDF Louisville Intl

8h 49m1 stop Atlanta Hartsfield-Jackson

$321Delta

Tue, Sep 15 - Mon, Sep 21

7:05 am - 11:25 amSDF Louisville Intl-SAN San Diego

7h 20m1 stop Atlanta Hartsfield-Jackson

10:30 pm - 10:19 amSAN San Diego-SDF Louisville Intl

8h 49m1 stop Atlanta Hartsfield-Jackson

$321Delta

Thu, Sep 10 - Mon, Sep 14

Cheap last minute flights

Enter your travel dates to find the best prices.

6:55 pm - 11:48 amSDF Louisville Intl-SAN San Diego

19h 53m1 stop Pittsburgh

12:54 pm - 2:16 pmSAN San Diego-SDF Louisville Intl

22h 22m1 stop Raleigh-Durham

$468Breeze Airways

Sun, Aug 30 - Tue, Sep 1

8:46 pm - 11:24 amSDF Louisville Intl-SAN San Diego

17h 38m1 stop Raleigh-Durham

12:54 pm - 2:16 pmSAN San Diego-SDF Louisville Intl

22h 22m1 stop Raleigh-Durham

$490Breeze Airways

Sat, Aug 29 - Tue, Sep 1

6:55 pm - 11:48 amSDF Louisville Intl-SAN San Diego

19h 53m1 stop Pittsburgh

6:25 am - 2:16 pmSAN San Diego-SDF Louisville Intl

28h 51m2 stops Denver Intl Raleigh-Durham

$503Multiple Airlines

Sun, Aug 30 - Tue, Sep 1

5:45 pm - 10:10 pmSDF Louisville Intl-SAN San Diego

7h 25m1 stop Chicago O'Hare Intl

6:18 am - 4:38 pmSAN San Diego-SDF Louisville Intl

7h 20m1 stop Chicago O'Hare Intl

$697United Airlines

Sat, Aug 29 - Sat, Sep 5

9:00 am - 2:35 pmSDF Louisville Intl-SAN San Diego

8h 35m2 stops Chicago Midway Phoenix Sky Harbor Intl

10:45 am - 10:20 pmSAN San Diego-SDF Louisville Intl

8h 35m2 stops Las Vegas Harry Reid Intl Nashville Intl

$944Southwest

Sat, Aug 29 - Sun, Sep 13

1:19 pm - 6:18 pmSDF Louisville Intl-SAN San Diego

7h 59m2 stops Dallas/Fort Worth Phoenix Sky Harbor Intl

10:57 am - 10:17 pmSAN San Diego-SDF Louisville Intl

8h 20m2 stops Phoenix Sky Harbor Intl Dallas/Fort Worth

$956American Airlines

Sat, Aug 29 - Sat, Sep 5

11:05 am - 7:19 pmSDF Louisville Intl-SAN San Diego

11h 14m1 stop Chicago O'Hare Intl

6:15 am - 9:25 pmSAN San Diego-SDF Louisville Intl

12h 10m1 stop Chicago O'Hare Intl

$967American Airlines

Thu, Aug 27 - Mon, Aug 31

9:45 am - 1:17 pmSDF Louisville Intl-SAN San Diego

6h 32m1 stop Houston George Bush Intcntl

7:41 pm - 2:29 pmSAN San Diego-SDF Louisville Intl

15h 48m2 stops San Francisco Denver Intl

$982United Airlines

Sun, Aug 30 - Mon, Aug 31

6:00 am - 11:09 amSDF Louisville Intl-SAN San Diego

8h 09m1 stop Atlanta Hartsfield-Jackson

10:17 pm - 9:54 amSAN San Diego-SDF Louisville Intl

8h 37m1 stop Detroit Metropolitan Wayne County

$997Delta

Sat, Aug 29 - Mon, Aug 31

11:17 am - 5:04 pmSDF Louisville Intl-SAN San Diego

8h 47m1 stop Atlanta Hartsfield-Jackson

6:15 am - 4:41 pmSAN San Diego-SDF Louisville Intl

7h 26m1 stop Detroit Metropolitan Wayne County

$1,062Delta

Thu, Aug 27 - Sat, Aug 29

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Delta flights from Louisville to San Diego

Our best Delta deals on Louisville to San Diego flight tickets

Delta

Sep 9

SDF6:00 amLouisville Intl

6h 45m

1 stop

SAN9:45 amSan Diego

Sep 9

SAN2:00 pmSan Diego

6h 59m

1 stop

SDF11:59 pmLouisville Intl

$321

Delta

Dec 11

SDF3:18 pmLouisville Intl

9h 57m

1 stop

SAN10:15 pmSan Diego

Dec 17

SAN6:15 amSan Diego

7h 38m

1 stop

SDF4:53 pmLouisville Intl

$334

Delta

Sep 18

SDF4:29 pmLouisville Intl

7h 08m

1 stop

SAN8:37 pmSan Diego

Sep 25

SAN10:30 pmSan Diego

8h 49m

1 stop

SDF10:19 amLouisville Intl

$347

American Airlines flights from Louisville to San Diego

Our best American Airlines deals on Louisville to San Diego flight tickets

American Airlines

Sep 16

SDF4:35 pmLouisville Intl

9h 50m

1 stop

SAN11:25 pmSan Diego

Sep 23

SAN10:46 pmSan Diego

7h 57m

1 stop

SDF9:43 amLouisville Intl

$342

American Airlines

Sep 16

SDF4:35 pmLouisville Intl

9h 50m

1 stop

SAN11:25 pmSan Diego

Sep 23

SAN10:46 pmSan Diego

7h 57m

1 stop

SDF9:43 amLouisville Intl

$346

American Airlines

Sep 16

SDF4:35 pmLouisville Intl

9h 50m

1 stop

SAN11:25 pmSan Diego

Sep 23

SAN10:46 pmSan Diego

7h 57m

1 stop

SDF9:43 amLouisville Intl

$348

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Sat 9/12

10:56 am-11:51 pm

2 stops15h 55m

San Diego

Tue 9/15

1:22 pm-10:11 am

1 stop17h 49m

$303

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Sat 9/12

10:56 am-11:51 pm

2 stops15h 55m

San Diego

Tue 9/15

1:22 pm-10:11 am

1 stop17h 49m

$304

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Wed 9/9

6:45 pm-10:40 pm

1 stop6h 55m

San Diego

Thu 9/10

2:30 pm-11:10 pm

1 stop5h 40m

$316

Quickest round-trip

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Wed 10/14

7:10 pm-10:05 pm

1 stop5h 55m

San Diego

Wed 10/21

6:30 am-3:15 pm

1 stop5h 45m

$316

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Wed 10/21

4:18 pm-9:46 pm

1 stop8h 28m

San Diego

Mon 10/26

7:15 am-6:37 pm

1 stop8h 22m

$321

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Wed 10/14

5:04 am-9:10 am

1 stop7h 06m

San Diego

Sat 10/17

6:20 am-6:37 pm

1 stop9h 17m

$321

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Mon 11/23

2:10 pm-6:34 pm

1 stop7h 24m

San Diego

Wed 12/2

12:45 pm-9:57 pm

1 stop6h 12m

$321

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Wed 9/16

5:15 am-9:32 am

1 stop7h 17m

San Diego

Wed 9/23

12:45 pm-11:59 pm

1 stop8h 14m

$321

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Tue 9/15

4:29 pm-8:37 pm

1 stop7h 08m

San Diego

Mon 9/21

10:30 pm-10:19 am

1 stop8h 49m

$321

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Thu 9/10

7:05 am-11:25 am

1 stop7h 20m

San Diego

Mon 9/14

10:30 pm-10:19 am

1 stop8h 49m

$321

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Louisville to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the typical price of a round-trip flight between Louisville and San Diego?

Prices are currently low for flights on this route.

Typical prices usually range from $376 to $484.
The lowest price recently found on this route was $303.

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of February, then departing from Louisville during the month January is also very affordable. Most momondo users find prices during this month for around $396.

How far in advance should I book a flight from Louisville to San Diego?

You are more likely to see cheaper flights to San Diego from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $454 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Louisville for as low as $372 on momondo.

How have Louisville to San Diego flight prices changed over time?

As of August 2026, prices for Louisville to San Diego flights are approximately 124% more expensive when compared to flights at the same time last year.

When to book flights from Louisville to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to San Diego according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Louisville to San Diego (SDF to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to San Diego

Best Price Found	$161
Fastest flight time	5h 55m
Direct flights	None

The best one-way flight to San Diego from Louisville in the past 72 hours is $161. The best round-trip flight deal from Louisville to San Diego found on momondo in the last 72 hours is $303.

The fastest flight from Louisville to San Diego takes 5h 55m

There are no direct flights from Louisville to San Diego. There are no popular flight routes from Louisville to San Diego.

Search flight deals

Frequently asked questions about flying from Louisville to San Diego

How far is Louisville Intl to San Diego by plane?
The straight-line distance from Louisville Intl to San Diego is 1797.3 mi. Flights usually cover this in 5h 55m, depending on flying conditions and air traffic around both airports.
When did momondo last update prices for flights from Louisville Intl Airport to San Diego Airport?
Prices for flights from Louisville Intl Airport to San Diego Airport were last updated today.
How many operators does momondo search for flights from Louisville Intl Airport to San Diego Airport?
As of August 2026, there are 4 operators available to choose from for flights from Louisville Intl Airport to San Diego Airport.
How old do you have to be to fly from Louisville Intl Airport to San Diego Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to San Diego Airport.
What documentation or ID do you need to fly to San Diego Airport?
The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Louisville to San Diego?
momondo data reveals that the most frequently booked airline on the route from Louisville to San Diego is American Airlines, representing 35% of all bookings. The subsequent popular airlines are Southwest at 35%, United Airlines at 17%, and Delta at 14%.

Best airlines flying from Louisville to San Diego

Compare and see reviews for airlines that fly from Louisville to San Diego with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $263	Free Cancellation	Rating 7.4 10,121 reviews	Search United Airlines flights
Delta	PriceFrom $276	Free Cancellation	Rating 7.8 8,529 reviews	Search Delta flights
American Airlines	PriceFrom $293	Free Cancellation	Rating 7.1 11,995 reviews	Search American Airlines flights
Southwest	PriceFrom $341	Free Cancellation	Rating 8.0 4,204 reviews	Search Southwest flights

Chula Vista

Coronado

El Cajon

National City

Julian

La Mesa

Poway

San Ysidro

Imperial Beach

Santee

Borrego Springs

Lemon Grove

Alpine

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Louisville to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Louisville to San Diego with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Diego from Louisville with this policy.

How can momondo help me find flights from Louisville to San Diego?

momondo helps you find the best flight between Louisville and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Louisville to San Diego right now. Can momondo alert me if prices change?

Price alerts on flights to San Diego from Louisville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your San Diego trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

1 adult

Fri 9/25

Fri 10/2

Email me momondo's favorite deals

By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States

Nearby airports

Airlines

Cabin classes

Other United States destinations

Other flights from Louisville

Complete your trip

Feeling lucky

Cheap flights from Louisville to San Diego from $161

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to San Diego departing on 9/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Find the cheapest flights from Louisville to San Diego

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Delta flights from Louisville to San Diego

Our best Delta deals on Louisville to San Diego flight tickets

American Airlines flights from Louisville to San Diego

Our best American Airlines deals on Louisville to San Diego flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Louisville to San Diego that are best for you.

See travel insights to San Diego from

How to get the cheapest flight ticket from Louisville to San Diego

What is the typical price of a round-trip flight between Louisville and San Diego?

What is the cheapest month to fly to San Diego?

How far in advance should I book a flight from Louisville to San Diego?

How have Louisville to San Diego flight prices changed over time?

What is the cheapest airline that flies from Louisville Intl to San Diego?

What airlines fly to San Diego?

When to book flights from Louisville to San Diego

Cheap Louisville to San Diego (SDF to SAN) flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Louisville to San Diego

Best airlines flying from Louisville to San Diego

Compare and see reviews for airlines that fly from Louisville to San Diego with momondo

Traveling to a place near San Diego?

Why use momondo?

An easier way to manage your San Diego trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing California

Fly your favorite airline to San Diego

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to San Diego

List of cabin classes available on flights landing in San Diego. Availability may vary depending on flight origin and airline.

Popular cities in the United States

Popular flights according to clicks in the last 7 days on momondo

Fly to other destinations from Louisville

According to popular flight searches on momondo this year

Complete your trip to San Diego

Explore popular destinations other users love

According to popular flight searches on momondo this year