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Cheap flights from Louisville to San Diego from $150

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Louisville to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:27 pm - 11:38 pmSDF  Louisville Intl-SAN San Diego
7h 11m1 stop Dallas/Fort Worth
American Airlines Logo
10:40 pm - 9:32 amSAN  San Diego-SDF Louisville Intl
7h 52m1 stop Chicago O'Hare Intl
$299American Airlines
Wed, Oct 14 - Sat, Oct 17
Delta Logo
7:00 am - 10:48 amSDF  Louisville Intl-SAN San Diego
6h 48m1 stop Minneapolis St Paul
Delta Logo
2:10 pm - 11:59 pmSAN  San Diego-SDF Louisville Intl
6h 49m1 stop Atlanta Hartsfield-Jackson
$299Delta
Tue, Oct 6 - Wed, Oct 7
Southwest Logo
6:15 pm - 12:35 amSDF  Louisville Intl-SAN San Diego
9h 20m1 stop Nashville Intl
Southwest Logo
6:30 am - 3:15 pmSAN  San Diego-SDF Louisville Intl
5h 45m1 stop Dallas Love Field
$316Southwest
Mon, Oct 19 - Tue, Oct 27
Southwest Logo
5:10 pm - 12:15 amSDF  Louisville Intl-SAN San Diego
10h 05m1 stop Baltimore/Washington
Southwest Logo
6:30 am - 3:15 pmSAN  San Diego-SDF Louisville Intl
5h 45m1 stop Dallas Love Field
$316Southwest
Mon, Oct 19 - Tue, Oct 27
Delta Logo
5:55 pm - 10:54 pmSDF  Louisville Intl-SAN San Diego
7h 59m1 stop Atlanta Hartsfield-Jackson
Delta Logo
2:10 pm - 11:59 pmSAN  San Diego-SDF Louisville Intl
6h 49m1 stop Atlanta Hartsfield-Jackson
$320Delta
Mon, Oct 5 - Wed, Oct 7
United Airlines Logo
3:36 pm - 8:39 pmSDF  Louisville Intl-SAN San Diego
8h 03m1 stop Denver Intl
United Airlines Logo
10:30 pm - 9:34 amSAN  San Diego-SDF Louisville Intl
8h 04m1 stop Chicago O'Hare Intl
$321United Airlines
Tue, Oct 20 - Wed, Oct 21
United Airlines Logo
3:24 pm - 8:36 pmSDF  Louisville Intl-SAN San Diego
8h 12m1 stop Denver Intl
United Airlines Logo
10:30 pm - 9:38 amSAN  San Diego-SDF Louisville Intl
8h 08m1 stop Chicago O'Hare Intl
$321United Airlines
Wed, Nov 4 - Sat, Nov 7
American Airlines Logo
6:00 am - 10:27 amSDF  Louisville Intl-SAN San Diego
7h 27m1 stop Dallas/Fort Worth
American Airlines Logo
7:15 am - 6:37 pmSAN  San Diego-SDF Louisville Intl
8h 22m1 stop Dallas/Fort Worth
$321American Airlines
Wed, Oct 21 - Mon, Oct 26
Multiple Airlines Logo
8:47 am - 1:16 pmSDF  Louisville Intl-SAN San Diego
31h 29m1 stop San Francisco
Multiple Airlines Logo
1:22 pm - 10:11 amSAN  San Diego-SDF Louisville Intl
17h 49m1 stop Raleigh-Durham
$324Multiple Airlines
Fri, Oct 23 - Tue, Oct 27
Multiple Airlines Logo
8:47 am - 6:38 pmSDF  Louisville Intl-SAN San Diego
12h 51m1 stop San Francisco
Multiple Airlines Logo
10:56 am - 7:19 pmSAN  San Diego-SDF Louisville Intl
29h 23m1 stop San Francisco
$349Multiple Airlines
Fri, Oct 30 - Sun, Nov 8

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Delta flights from Louisville to San Diego

Our best Delta deals on Louisville to San Diego flight tickets
Delta
Oct 6
SDF7:00 amLouisville Intl
6h 48m
1 stop
SAN10:48 amSan Diego
Oct 7
SAN2:10 pmSan Diego
6h 49m
1 stop
SDF11:59 pmLouisville Intl
$299
Delta
Oct 5
SDF5:55 pmLouisville Intl
7h 59m
1 stop
SAN10:54 pmSan Diego
Oct 7
SAN2:10 pmSan Diego
6h 49m
1 stop
SDF11:59 pmLouisville Intl
$320
Delta
Jan 30
SDF6:00 amLouisville Intl
7h 10m
1 stop
SAN10:10 amSan Diego
Feb 3
SAN6:15 amSan Diego
8h 25m
1 stop
SDF5:40 pmLouisville Intl
$321

United Airlines flights from Louisville to San Diego

Our best United Airlines deals on Louisville to San Diego flight tickets
United Airlines
Oct 23
SDF5:15 amLouisville Intl
7h 17m
1 stop
SAN9:32 amSan Diego
Oct 27
SAN6:45 amSan Diego
8h 47m
2 stops
SDF6:32 pmLouisville Intl
$346
United Airlines
Oct 12
SDF5:15 amLouisville Intl
7h 17m
1 stop
SAN9:32 amSan Diego
Oct 14
SAN10:30 pmSan Diego
8h 04m
1 stop
SDF9:34 amLouisville Intl
$375
United Airlines
Jan 25
SDF5:57 pmLouisville Intl
7h 40m
1 stop
SAN10:37 pmSan Diego
Feb 1
SAN8:50 amSan Diego
8h 42m
2 stops
SDF8:32 pmLouisville Intl
$385

momondo Fare Finder

 
Use the filters below to find and compare flights from Louisville to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Wed 10/14

7:27 pm-11:38 pm

1 stop7h 11m

San Diego

Sat 10/17

10:40 pm-9:32 am

1 stop7h 52m

$299
Quickest round-trip

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Tue 10/6

7:00 am-10:48 am

1 stop6h 48m

San Diego

Wed 10/7

2:10 pm-11:59 pm

1 stop6h 49m

$299

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Mon 10/19

6:15 pm-12:35 am

1 stop9h 20m

San Diego

Tue 10/27

6:30 am-3:15 pm

1 stop5h 45m

$316

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Mon 10/19

5:10 pm-12:15 am

1 stop10h 05m

San Diego

Tue 10/27

6:30 am-3:15 pm

1 stop5h 45m

$316

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Mon 10/5

5:55 pm-10:54 pm

1 stop7h 59m

San Diego

Wed 10/7

2:10 pm-11:59 pm

1 stop6h 49m

$320

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Tue 10/20

3:36 pm-8:39 pm

1 stop8h 03m

San Diego

Wed 10/21

10:30 pm-9:34 am

1 stop8h 04m

$321

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Wed 11/4

3:24 pm-8:36 pm

1 stop8h 12m

San Diego

Sat 11/7

10:30 pm-9:38 am

1 stop8h 08m

$321

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Wed 10/21

6:00 am-10:27 am

1 stop7h 27m

San Diego

Mon 10/26

7:15 am-6:37 pm

1 stop8h 22m

$321

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Fri 10/23

8:47 am-1:16 pm

1 stop31h 29m

San Diego

Tue 10/27

1:22 pm-10:11 am

1 stop17h 49m

$324

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Fri 10/30

8:47 am-6:38 pm

1 stop12h 51m

San Diego

Sun 11/8

10:56 am-7:19 pm

1 stop29h 23m

$349

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Louisville to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Louisville and San Diego?

Prices are currently low for flights on this route.

Typical prices usually range from $382 to $525.
The lowest price recently found on this route was $299.

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of February, then departing from Louisville during the month November is also very affordable. Most momondo users find prices during this month for around $426.

How far in advance should I book a flight from Louisville to San Diego?

You are more likely to see cheaper flights to San Diego from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $458 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Louisville for as low as $381 on momondo.

How have Louisville to San Diego flight prices changed over time?

As of September 2026, prices for Louisville to San Diego flights are approximately 18% cheaper when compared to flights at the same time last year.

When to book flights from Louisville to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to San Diego (SDF to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to San Diego

Best Price Found

$150

Fastest flight time

7h 00m

Direct flights

None
The best one-way flight to San Diego from Louisville in the past 72 hours is $150. The best round-trip flight deal from Louisville to San Diego found on momondo in the last 72 hours is $299.
The fastest flight from Louisville to San Diego takes 7h 00m
There are no direct flights from Louisville to San Diego. There are no popular flight routes from Louisville to San Diego.
Search flight deals

Frequently asked questions about flying from Louisville to San Diego

  • How far is Louisville Intl to San Diego by plane?

    The straight-line distance from Louisville Intl to San Diego is 1797.3 mi. Flights usually cover this in 7h 00m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Louisville Intl Airport to San Diego Airport?

    Prices for flights from Louisville Intl Airport to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Louisville Intl Airport to San Diego Airport?

  • How old do you have to be to fly from Louisville Intl Airport to San Diego Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Louisville to San Diego?

Best airlines flying from Louisville to San Diego

Compare and see reviews for airlines that fly from Louisville to San Diego with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $276Free CancellationRating
7.8
8,595 reviews
Search Delta flights
American AirlinesPriceFrom $299Free CancellationRating
7.0
12,082 reviews
Search American Airlines flights
United AirlinesPriceFrom $333Free CancellationRating
7.4
10,225 reviews
Search United Airlines flights
SouthwestPriceFrom $333Free CancellationRating
8.0
4,195 reviews
Search Southwest flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Chula Vista
El Cajon
Coronado
National City
La Mesa
Julian
Poway
San Ysidro
Imperial Beach
Santee
Alpine
Lemon Grove
Borrego Springs

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Louisville to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Louisville to San Diego with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Diego from Louisville with this policy.

How can momondo help me find flights from Louisville to San Diego?

momondo helps you find the best flight between Louisville and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Louisville to San Diego right now. Can momondo alert me if prices change?

Price alerts on flights to San Diego from Louisville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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