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Cheap flights from Louisville to San Diego from $113

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to San Diego departing on 2/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Louisville to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
9:00 am - 12:57 pm
SDF
-
SAN
6h 57m1 stop
United Airlines Logo
10:30 am - 7:51 pm
SAN
-
SDF
6h 21m1 stop
$255United Airlines
Tue, Feb 24 - Tue, Mar 3
United Airlines Logo
9:00 am - 3:00 pm
SDF
-
SAN
9h 00m2 stops
United Airlines Logo
10:59 am - 10:13 pm
SAN
-
SDF
8h 14m1 stop
$260United Airlines
Tue, Feb 24 - Tue, Mar 3
American Airlines Logo
11:14 am - 4:54 pm
SDF
-
SAN
8h 40m1 stop
American Airlines Logo
12:09 pm - 10:43 pm
SAN
-
SDF
7h 34m1 stop
$267American Airlines
Wed, Feb 11 - Sat, Feb 14
Delta Logo
3:33 pm - 10:48 pm
SDF
-
SAN
10h 15m1 stop
Delta Logo
11:16 am - 8:28 pm
SAN
-
SDF
6h 12m1 stop
$277Delta
Mon, Feb 23 - Tue, Mar 3
United Airlines Logo
9:50 am - 3:41 pm
SDF
-
SAN
8h 51m1 stop
United Airlines Logo
10:30 pm - 1:06 pm
SAN
-
SDF
11h 36m1 stop
$279United Airlines
Fri, Feb 20 - Mon, Feb 23
American Airlines Logo
8:07 am - 1:08 pm
SDF
-
SAN
8h 01m1 stop
American Airlines Logo
6:15 am - 5:33 pm
SAN
-
SDF
8h 18m2 stops
$284American Airlines
Wed, Jan 28 - Sat, Jan 31
Southwest Logo
12:50 pm - 5:25 pm
SDF
-
SAN
7h 35m1 stop
Southwest Logo
9:40 am - 9:10 pm
SAN
-
SDF
8h 30m2 stops
$289Southwest
Tue, Jan 20 - Tue, Jan 27
Delta Logo
3:37 pm - 10:45 pm
SDF
-
SAN
10h 08m1 stop
Delta Logo
10:00 pm - 10:01 am
SAN
-
SDF
9h 01m1 stop
$290Delta
Sat, Jan 17 - Tue, Jan 27
American Airlines Logo
6:00 am - 2:17 pm
SDF
-
SAN
11h 17m1 stop
American Airlines Logo
6:40 am - 5:56 pm
SAN
-
SDF
8h 16m1 stop
$296American Airlines
Sat, Apr 25 - Tue, Apr 28
American Airlines Logo
6:00 am - 11:33 am
SDF
-
SAN
8h 33m1 stop
American Airlines Logo
7:10 am - 5:33 pm
SAN
-
SDF
7h 23m1 stop
$311American Airlines
Wed, Jan 28 - Sat, Jan 31

Southwest flights from Louisville to San Diego

Our best Southwest deals on Louisville to San Diego flight tickets
Southwest
Jan 20
SDF12:50 pmLouisville Intl
7h 35m
1 stop
SAN5:25 pmSan Diego
Jan 27
SAN10:30 amSan Diego
8h 20m
1 stop
SDF9:50 pmLouisville Intl
$279
Find similar
Southwest
Jan 20
SDF12:50 pmLouisville Intl
7h 35m
1 stop
SAN5:25 pmSan Diego
Jan 27
SAN9:40 amSan Diego
8h 30m
2 stops
SDF9:10 pmLouisville Intl
$289
Find similar
Southwest
Mar 11
SDF1:30 pmLouisville Intl
9h 05m
2 stops
SAN7:35 pmSan Diego
Mar 18
SAN9:20 pmSan Diego
9h 35m
2 stops
SDF9:55 amLouisville Intl
$332
Find similar

American Airlines flights from Louisville to San Diego

Our best American Airlines deals on Louisville to San Diego flight tickets
American Airlines
Feb 11
SDF11:14 amLouisville Intl
8h 40m
1 stop
SAN4:54 pmSan Diego
Feb 14
SAN12:09 pmSan Diego
7h 34m
1 stop
SDF10:43 pmLouisville Intl
$267
Find similar
American Airlines
Jan 28
SDF8:07 amLouisville Intl
8h 01m
1 stop
SAN1:08 pmSan Diego
Jan 31
SAN6:15 amSan Diego
8h 18m
2 stops
SDF5:33 pmLouisville Intl
$284
Find similar
American Airlines
Apr 25
SDF6:00 amLouisville Intl
11h 17m
1 stop
SAN2:17 pmSan Diego
Apr 28
SAN6:40 amSan Diego
8h 16m
1 stop
SDF5:56 pmLouisville Intl
$296
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 7, 2026.
Use the filters below to find and compare flights from Louisville to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 2/24

9:00 am-12:57 pm

1 stop6h 57m

San Diego

Tue 3/3

10:30 am-7:51 pm

1 stop6h 21m

$255

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 2/24

9:00 am-3:00 pm

2 stops9h 00m

San Diego

Tue 3/3

10:59 am-10:13 pm

1 stop8h 14m

$260

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 2/11

11:14 am-4:54 pm

1 stop8h 40m

San Diego

Sat 2/14

12:09 pm-10:43 pm

1 stop7h 34m

$267

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Mon 2/23

3:33 pm-10:48 pm

1 stop10h 15m

San Diego

Tue 3/3

11:16 am-8:28 pm

1 stop6h 12m

$277

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Fri 2/20

9:50 am-3:41 pm

1 stop8h 51m

San Diego

Mon 2/23

10:30 pm-1:06 pm

1 stop11h 36m

$279

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 1/28

8:07 am-1:08 pm

1 stop8h 01m

San Diego

Sat 1/31

6:15 am-5:33 pm

2 stops8h 18m

$284

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 1/20

12:50 pm-5:25 pm

1 stop7h 35m

San Diego

Tue 1/27

9:40 am-9:10 pm

2 stops8h 30m

$289

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Sat 1/17

3:37 pm-10:45 pm

1 stop10h 08m

San Diego

Tue 1/27

10:00 pm-10:01 am

1 stop9h 01m

$290

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Sat 4/25

6:00 am-2:17 pm

1 stop11h 17m

San Diego

Tue 4/28

6:40 am-5:56 pm

1 stop8h 16m

$296

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 1/28

6:00 am-11:33 am

1 stop8h 33m

San Diego

Sat 1/31

7:10 am-5:33 pm

1 stop7h 23m

$311

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Louisville to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of August, then departing from Louisville during the month September is also very affordable. Most momondo users find prices during this month for around $384.

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $431 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Louisville for as low as $347 on momondo.

How have Louisville to San Diego flight prices changed over time?

As of January 2026, prices for Louisville to San Diego flights are approximately 29% cheaper when compared to flights at the same time last year.

When to book flights from Louisville to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to San Diego (SDF to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to San Diego

Fastest flight time

6h 54m

Direct flights

None
The fastest flight from Louisville to San Diego takes 6h 54m
There are no direct flights from Louisville to San Diego. There are no popular flight routes from Louisville to San Diego.
Search flight deals

  • How far is Louisville Intl to San Diego by plane?

    The straight-line distance from Louisville Intl to San Diego is 1797.3 mi. Flights usually cover this in 6h 54m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Louisville Intl Airport to San Diego Airport?

    Prices for flights from Louisville Intl Airport to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Louisville Intl Airport to San Diego Airport?

  • How old do you have to be to fly from Louisville Intl Airport to San Diego Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Louisville to San Diego?

Best airlines flying from Louisville to San Diego

Compare and see reviews for airlines that fly from Louisville to San Diego with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $232Free CancellationRating
6.3
8,287 reviews
Search Spirit Airlines flights
United AirlinesPriceFrom $260Free CancellationRating
7.4
9,139 reviews
Search United Airlines flights
DeltaPriceFrom $276Free CancellationRating
7.9
8,025 reviews
Search Delta flights
American AirlinesPriceFrom $294Free CancellationRating
7.2
11,095 reviews
Search American Airlines flights
SouthwestPriceFrom $336Free CancellationRating
8.0
4,248 reviews
Search Southwest flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
Poway
National City
Imperial Beach
Borrego Springs
La Mesa
San Ysidro
Alpine
Lemon Grove
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Louisville to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Louisville to San Diego with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Diego from Louisville with this policy.

How can momondo help me find flights from Louisville to San Diego?

momondo helps you find the best flight between Louisville and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Louisville to San Diego right now. Can momondo alert me if prices change?

Price alerts on flights to San Diego from Louisville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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