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Cheap flights from Louisville to San Diego from $130

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to San Diego departing on 5/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Louisville to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
Breeze Airways Logo
6:55 pm - 11:48 am
SDF
-
SAN
19h 53m
1 stop
Breeze Airways Logo
12:54 pm - 8:36 am
SAN
-
SDF
16h 42m
1 stop
$298Breeze Airways
Thu, Aug 20 - Tue, Aug 25
Multiple Airlines Logo
8:06 pm - 11:24 am
SDF
-
SAN
18h 18m
1 stop
Multiple Airlines Logo
6:25 am - 9:03 am
SAN
-
SDF
23h 38m
2 stops
$320Multiple Airlines
Wed, May 6 - Wed, May 13
Delta Logo
4:28 pm - 8:35 pm
SDF
-
SAN
7h 07m
1 stop
Delta Logo
2:31 pm - 12:32 am
SAN
-
SDF
7h 01m
1 stop
$321Delta
Wed, Jun 3 - Wed, Jun 10
Southwest Logo
8:25 am - 1:45 pm
SDF
-
SAN
8h 20m
2 stops
Southwest Logo
10:40 pm - 10:05 am
SAN
-
SDF
8h 25m
1 stop
$326Southwest
Wed, Jun 3 - Tue, Jun 9
Delta Logo
5:50 pm - 11:28 pm
SDF
-
SAN
8h 38m
1 stop
Delta Logo
6:20 am - 5:19 pm
SAN
-
SDF
7h 59m
1 stop
$327Delta
Sat, Jun 6 - Tue, Jun 9
Southwest Logo
4:40 pm - 9:30 pm
SDF
-
SAN
7h 50m
2 stops
Southwest Logo
9:35 pm - 9:55 am
SAN
-
SDF
9h 20m
2 stops
$331Southwest
Wed, May 6 - Wed, May 13
Southwest Logo
4:40 pm - 9:30 pm
SDF
-
SAN
7h 50m
2 stops
Southwest Logo
6:30 am - 4:55 pm
SAN
-
SDF
7h 25m
1 stop
$332Southwest
Wed, May 6 - Sat, May 9
American Airlines Logo
7:01 pm - 11:33 pm
SDF
-
SAN
7h 32m
1 stop
American Airlines Logo
12:17 pm - 11:11 pm
SAN
-
SDF
7h 54m
1 stop
$333American Airlines
Mon, May 11 - Thu, May 14
Multiple Airlines Logo
6:55 pm - 3:31 pm
SDF
-
SAN
47h 36m
2 stops
Multiple Airlines Logo
12:54 pm - 8:36 am
SAN
-
SDF
16h 42m
1 stop
$336Multiple Airlines
Sun, May 10 - Tue, May 19
Southwest Logo
7:00 am - 12:10 pm
SDF
-
SAN
8h 10m
2 stops
Southwest Logo
8:20 am - 8:50 pm
SAN
-
SDF
9h 30m
2 stops
$337Southwest
Wed, May 6 - Sat, May 9

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 9, 2026.
Use the filters below to find and compare flights from Louisville to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Thu 8/20

6:55 pm-11:48 am

1 stop19h 53m

San Diego

Tue 8/25

12:54 pm-8:36 am

1 stop16h 42m

$298

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 5/6

8:06 pm-11:24 am

1 stop18h 18m

San Diego

Wed 5/13

6:25 am-9:03 am

2 stops23h 38m

$320
Quickest round-trip

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 6/3

4:28 pm-8:35 pm

1 stop7h 07m

San Diego

Wed 6/10

2:31 pm-12:32 am

1 stop7h 01m

$321

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 6/3

8:25 am-1:45 pm

2 stops8h 20m

San Diego

Tue 6/9

10:40 pm-10:05 am

1 stop8h 25m

$326

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Sat 6/6

5:50 pm-11:28 pm

1 stop8h 38m

San Diego

Tue 6/9

6:20 am-5:19 pm

1 stop7h 59m

$327

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 5/6

4:40 pm-9:30 pm

2 stops7h 50m

San Diego

Wed 5/13

9:35 pm-9:55 am

2 stops9h 20m

$331

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 5/6

4:40 pm-9:30 pm

2 stops7h 50m

San Diego

Sat 5/9

6:30 am-4:55 pm

1 stop7h 25m

$332

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Mon 5/11

7:01 pm-11:33 pm

1 stop7h 32m

San Diego

Thu 5/14

12:17 pm-11:11 pm

1 stop7h 54m

$333

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Sun 5/10

6:55 pm-3:31 pm

2 stops47h 36m

San Diego

Tue 5/19

12:54 pm-8:36 am

1 stop16h 42m

$336

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 5/6

7:00 am-12:10 pm

2 stops8h 10m

San Diego

Sat 5/9

8:20 am-8:50 pm

2 stops9h 30m

$337

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Louisville to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Louisville and San Diego?

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of August, then departing from Louisville during the month January is also very affordable. Most momondo users find prices during this month for around $383.

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $441 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Louisville for as low as $347 on momondo.

How have Louisville to San Diego flight prices changed over time?

As of April 2026, prices for Louisville to San Diego flights are approximately 7% more expensive when compared to flights at the same time last year.

When to book flights from Louisville to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Frequently asked questions about flying from Louisville to San Diego

  • How far is Louisville Intl to San Diego by plane?

    The straight-line distance from Louisville Intl to San Diego is 1797.3 mi. Flights usually cover this in 6h 25m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Louisville Intl Airport to San Diego Airport?

    Prices for flights from Louisville Intl Airport to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Louisville Intl Airport to San Diego Airport?

  • How old do you have to be to fly from Louisville Intl Airport to San Diego Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Louisville to San Diego?

Best airlines flying from Louisville to San Diego

Compare and see reviews for airlines that fly from Louisville to San Diego with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $112Free CancellationRating
6.3
8,605 reviews
Search Spirit Airlines flights
DeltaPriceFrom $239Free CancellationRating
7.9
8,396 reviews
Search Delta flights
United AirlinesPriceFrom $260Free CancellationRating
7.4
9,558 reviews
Search United Airlines flights
American AirlinesPriceFrom $282Free CancellationRating
7.1
11,567 reviews
Search American Airlines flights
SouthwestPriceFrom $336Free CancellationRating
8.0
4,337 reviews
Search Southwest flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
Poway
San Ysidro
Imperial Beach
La Mesa
Lemon Grove
Borrego Springs
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Louisville to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Louisville to San Diego with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Diego from Louisville with this policy.

How can momondo help me find flights from Louisville to San Diego?

momondo helps you find the best flight between Louisville and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Louisville to San Diego right now. Can momondo alert me if prices change?

Price alerts on flights to San Diego from Louisville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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