What is the cheapest airline that flies from Louisville Intl to San Diego?

American Airlines, United Airlines, and Delta are the most popular carriers operating from Louisville Intl to San Diego

What airlines fly to San Diego?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to San Diego from Louisville according to our data. American Airlines is the first choice among our users, with 45% of people opting to fly with this airline when traveling to San Diego. Keep in mind that there are 7 different airlines that fly to San Diego on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Louisville Intl Airport to San Diego Airport?

Prices for flights from Louisville Intl Airport to San Diego Airport were last updated today.

How many operators does momondo search for flights from Louisville Intl Airport to San Diego Airport?

As of September 2026, there are 4 operators available to choose from for flights from Louisville Intl Airport to San Diego Airport.

How old do you have to be to fly from Louisville Intl Airport to San Diego Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to San Diego Airport.

What documentation or ID do you need to fly to San Diego Airport?

The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$161 Cheap Flights from Louisville to San Diego in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Louisville to San Diego

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

8:05 am - 1:08 pmSDF Louisville Intl-SAN San Diego

8h 03m1 stop Atlanta Hartsfield-Jackson

10:10 pm - 10:09 amSAN San Diego-SDF Louisville Intl

8h 59m1 stop Detroit Metropolitan Wayne County

$321Delta

Thu, Nov 12 - Mon, Nov 16

6:00 am - 11:38 amSDF Louisville Intl-SAN San Diego

8h 38m1 stop Atlanta Hartsfield-Jackson

11:40 am - 10:55 pmSAN San Diego-SDF Louisville Intl

8h 15m1 stop Minneapolis St Paul

$321Delta

Wed, Nov 18 - Thu, Feb 18

10:15 am - 3:20 pmSDF Louisville Intl-SAN San Diego

8h 05m1 stop Phoenix Sky Harbor Intl

6:30 am - 3:35 pmSAN San Diego-SDF Louisville Intl

6h 05m1 stop Chicago Midway

$321Southwest

Wed, Dec 2 - Wed, Dec 9

5:59 pm - 9:48 pmSDF Louisville Intl-SAN San Diego

6h 49m1 stop Dallas/Fort Worth

10:40 pm - 9:32 amSAN San Diego-SDF Louisville Intl

7h 52m1 stop Chicago O'Hare Intl

$321American Airlines

Sat, Oct 3 - Wed, Oct 7

7:27 pm - 11:38 pmSDF Louisville Intl-SAN San Diego

7h 11m1 stop Dallas/Fort Worth

10:40 pm - 9:32 amSAN San Diego-SDF Louisville Intl

7h 52m1 stop Chicago O'Hare Intl

$321American Airlines

Sat, Oct 10 - Tue, Oct 13

10:15 am - 3:20 pmSDF Louisville Intl-SAN San Diego

8h 05m1 stop Phoenix Sky Harbor Intl

12:45 pm - 10:50 pmSAN San Diego-SDF Louisville Intl

7h 05m2 stops Las Vegas Harry Reid Intl Denver Intl

$326Southwest

Wed, Dec 2 - Wed, Dec 9

9:17 am - 2:55 pmSDF Louisville Intl-SAN San Diego

8h 38m2 stops Chicago O'Hare Intl Denver Intl

10:16 am - 8:33 pmSAN San Diego-SDF Louisville Intl

7h 17m1 stop Houston George Bush Intcntl

$326United Airlines

Sat, Oct 31 - Tue, Nov 3

5:30 am - 10:11 amSDF Louisville Intl-SAN San Diego

7h 41m1 stop Chicago O'Hare Intl

11:00 am - 9:57 pmSAN San Diego-SDF Louisville Intl

7h 57m2 stops Los Angeles Los Angeles Denver Intl

$350United Airlines

Fri, Feb 26 - Mon, Mar 1

11:39 am - 4:59 pmSDF Louisville Intl-SAN San Diego

32h 20m2 stops New Orleans Louis Armstrong Las Vegas Harry Reid Intl

1:22 pm - 8:31 pmSAN San Diego-SDF Louisville Intl

28h 09m1 stop Raleigh-Durham

$358Multiple Airlines

Mon, Oct 5 - Tue, Oct 13

10:56 am - 11:51 pmSDF Louisville Intl-SAN San Diego

15h 55m2 stops Raleigh-Durham Denver Intl

1:22 pm - 10:11 amSAN San Diego-SDF Louisville Intl

17h 49m1 stop Raleigh-Durham

$388Multiple Airlines

Sat, Sep 26 - Tue, Oct 27

Cheap last minute flights

Enter your travel dates to find the best prices.

8:47 am - 6:19 pmSDF Louisville Intl-SAN San Diego

12h 32m1 stop San Francisco

1:22 pm - 10:11 amSAN San Diego-SDF Louisville Intl

17h 49m1 stop Raleigh-Durham

$514Multiple Airlines

Fri, Sep 11 - Tue, Sep 15

8:47 am - 11:51 pmSDF Louisville Intl-SAN San Diego

18h 04m2 stops San Francisco Denver Intl

1:22 pm - 10:11 amSAN San Diego-SDF Louisville Intl

17h 49m1 stop Raleigh-Durham

$536Multiple Airlines

Fri, Sep 11 - Tue, Sep 15

10:56 am - 11:52 amSDF Louisville Intl-SAN San Diego

27h 56m1 stop Raleigh-Durham

5:54 pm - 7:19 pmSAN San Diego-SDF Louisville Intl

46h 25m2 stops Las Vegas Harry Reid Intl San Jose

$730Multiple Airlines

Sat, Sep 12 - Sat, Sep 19

2:47 pm - 11:25 pmSDF Louisville Intl-SAN San Diego

11h 38m1 stop Chicago O'Hare Intl

6:15 am - 3:28 pmSAN San Diego-SDF Louisville Intl

6h 13m1 stop Dallas/Fort Worth

$736American Airlines

Tue, Sep 15 - Tue, Sep 22

2:47 pm - 11:25 pmSDF Louisville Intl-SAN San Diego

11h 38m1 stop Chicago O'Hare Intl

12:58 pm - 11:22 pmSAN San Diego-SDF Louisville Intl

7h 24m1 stop Charlotte Douglas

$736American Airlines

Tue, Sep 15 - Sat, Sep 19

3:35 pm - 9:24 pmSDF Louisville Intl-SAN San Diego

8h 49m1 stop Houston George Bush Intcntl

12:04 pm - 10:15 pmSAN San Diego-SDF Louisville Intl

7h 11m1 stop Houston George Bush Intcntl

$842United Airlines

Tue, Sep 15 - Sat, Sep 19

10:50 am - 6:20 pmSDF Louisville Intl-SAN San Diego

10h 30m2 stops Dallas Love Field Houston Hobby

10:50 am - 9:35 pmSAN San Diego-SDF Louisville Intl

7h 45m1 stop Baltimore/Washington

$847Southwest

Tue, Sep 15 - Tue, Sep 22

6:45 am - 12:05 pmSDF Louisville Intl-SAN San Diego

8h 20m2 stops Nashville Intl Dallas Love Field

6:20 am - 5:20 pmSAN San Diego-SDF Louisville Intl

8h 00m2 stops Dallas Love Field Nashville Intl

$1,073Southwest

Sat, Sep 12 - Sat, Sep 19

7:05 am - 3:01 pmSDF Louisville Intl-SAN San Diego

10h 56m2 stops Atlanta Hartsfield-Jackson Los Angeles Los Angeles

6:15 am - 7:30 pmSAN San Diego-SDF Louisville Intl

10h 15m2 stops Los Angeles Los Angeles Atlanta Hartsfield-Jackson

$2,237Delta

Tue, Sep 15 - Sat, Sep 19

6:30 am - 3:01 pmSDF Louisville Intl-SAN San Diego

11h 31m2 stops Minneapolis St Paul Los Angeles Los Angeles

6:15 am - 10:50 pmSAN San Diego-SDF Louisville Intl

13h 35m2 stops Los Angeles Los Angeles Minneapolis St Paul

$2,247Delta

Tue, Sep 15 - Sat, Sep 19

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American Airlines flights from Louisville to San Diego

Our best American Airlines deals on Louisville to San Diego flight tickets

American Airlines

Oct 7

SDF5:19 pmLouisville Intl

9h 00m

1 stop

SAN11:19 pmSan Diego

Oct 14

SAN10:40 pmSan Diego

7h 52m

1 stop

SDF9:32 amLouisville Intl

$325

American Airlines

Oct 8

SDF5:19 pmLouisville Intl

9h 00m

1 stop

SAN11:19 pmSan Diego

Oct 15

SAN10:40 pmSan Diego

7h 52m

1 stop

SDF9:32 amLouisville Intl

$364

American Airlines

Oct 7

SDF5:19 pmLouisville Intl

9h 00m

1 stop

SAN11:19 pmSan Diego

Oct 11

SAN10:40 pmSan Diego

7h 52m

1 stop

SDF9:32 amLouisville Intl

$394

Southwest flights from Louisville to San Diego

Our best Southwest deals on Louisville to San Diego flight tickets

Southwest

Oct 23

SDF7:50 pmLouisville Intl

7h 00m

1 stop

SAN11:50 pmSan Diego

Oct 27

SAN6:30 amSan Diego

5h 45m

1 stop

SDF3:15 pmLouisville Intl

$328

Southwest

Nov 4

SDF7:35 pmLouisville Intl

6h 45m

1 stop

SAN11:20 pmSan Diego

Nov 7

SAN4:30 pmSan Diego

14h 35m

2 stops

SDF10:05 amLouisville Intl

$332

Southwest

Nov 4

SDF10:15 amLouisville Intl

8h 10m

2 stops

SAN3:25 pmSan Diego

Nov 7

SAN4:30 pmSan Diego

14h 35m

2 stops

SDF10:05 amLouisville Intl

$337

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Thu 11/12

8:05 am-1:08 pm

1 stop8h 03m

San Diego

Mon 11/16

10:10 pm-10:09 am

1 stop8h 59m

$321

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Wed 11/18

6:00 am-11:38 am

1 stop8h 38m

San Diego

Thu 2/18

11:40 am-10:55 pm

1 stop8h 15m

$321

Quickest round-trip

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Wed 12/2

10:15 am-3:20 pm

1 stop8h 05m

San Diego

Wed 12/9

6:30 am-3:35 pm

1 stop6h 05m

$321

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Sat 10/3

5:59 pm-9:48 pm

1 stop6h 49m

San Diego

Wed 10/7

10:40 pm-9:32 am

1 stop7h 52m

$321

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Sat 10/10

7:27 pm-11:38 pm

1 stop7h 11m

San Diego

Tue 10/13

10:40 pm-9:32 am

1 stop7h 52m

$321

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Wed 12/2

10:15 am-3:20 pm

1 stop8h 05m

San Diego

Wed 12/9

12:45 pm-10:50 pm

2 stops7h 05m

$326

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Sat 10/31

9:17 am-2:55 pm

2 stops8h 38m

San Diego

Tue 11/3

10:16 am-8:33 pm

1 stop7h 17m

$326

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Fri 2/26

5:30 am-10:11 am

1 stop7h 41m

San Diego

Mon 3/1

11:00 am-9:57 pm

2 stops7h 57m

$350

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Mon 10/5

11:39 am-4:59 pm

2 stops32h 20m

San Diego

Tue 10/13

1:22 pm-8:31 pm

1 stop28h 09m

$358

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Sat 9/26

10:56 am-11:51 pm

2 stops15h 55m

San Diego

Tue 10/27

1:22 pm-10:11 am

1 stop17h 49m

$388

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Louisville to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the typical price of a round-trip flight between Louisville and San Diego?

Prices are currently low for flights on this route.

Typical prices usually range from $374 to $496.
The lowest price recently found on this route was $321.

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of February, then departing from Louisville during the month January is also very affordable. Most momondo users find prices during this month for around $396.

How far in advance should I book a flight from Louisville to San Diego?

You are more likely to see cheaper flights to San Diego from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $455 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Louisville for as low as $362 on momondo.

How have Louisville to San Diego flight prices changed over time?

As of September 2026, prices for Louisville to San Diego flights are approximately 18% cheaper when compared to flights at the same time last year.

When to book flights from Louisville to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to San Diego according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Louisville to San Diego (SDF to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to San Diego

Best Price Found	$161
Fastest flight time	6h 55m
Direct flights	None

The best one-way flight to San Diego from Louisville in the past 72 hours is $161. The best round-trip flight deal from Louisville to San Diego found on momondo in the last 72 hours is $321.

The fastest flight from Louisville to San Diego takes 6h 55m

There are no direct flights from Louisville to San Diego. There are no popular flight routes from Louisville to San Diego.

Search flight deals

Frequently asked questions about flying from Louisville to San Diego

How far is Louisville Intl to San Diego by plane?
The straight-line distance from Louisville Intl to San Diego is 1797.3 mi. Flights usually cover this in 6h 55m, depending on flying conditions and air traffic around both airports.
When did momondo last update prices for flights from Louisville Intl Airport to San Diego Airport?
Prices for flights from Louisville Intl Airport to San Diego Airport were last updated today.
How many operators does momondo search for flights from Louisville Intl Airport to San Diego Airport?
As of September 2026, there are 4 operators available to choose from for flights from Louisville Intl Airport to San Diego Airport.
How old do you have to be to fly from Louisville Intl Airport to San Diego Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to San Diego Airport.
What documentation or ID do you need to fly to San Diego Airport?
The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Louisville to San Diego?
momondo data reveals that the most frequently booked airline on the route from Louisville to San Diego is Southwest, representing 35% of all bookings. The subsequent popular airlines are American Airlines at 34%, United Airlines at 17%, and Delta at 14%.

Best airlines flying from Louisville to San Diego

Compare and see reviews for airlines that fly from Louisville to San Diego with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $276	Free Cancellation	Rating 7.8 8,554 reviews	Search Delta flights
United Airlines	PriceFrom $292	Free Cancellation	Rating 7.4 10,189 reviews	Search United Airlines flights
American Airlines	PriceFrom $299	Free Cancellation	Rating 7.1 12,045 reviews	Search American Airlines flights
Southwest	PriceFrom $333	Free Cancellation	Rating 8.0 4,195 reviews	Search Southwest flights

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Julian

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San Ysidro

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Santee

Alpine

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Borrego Springs

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Louisville to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Louisville to San Diego with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Diego from Louisville with this policy.

How can momondo help me find flights from Louisville to San Diego?

momondo helps you find the best flight between Louisville and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Louisville to San Diego right now. Can momondo alert me if prices change?

Price alerts on flights to San Diego from Louisville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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Cheap flights from Louisville to San Diego from $161

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to San Diego departing on 11/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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American Airlines flights from Louisville to San Diego

Our best American Airlines deals on Louisville to San Diego flight tickets

Southwest flights from Louisville to San Diego

Our best Southwest deals on Louisville to San Diego flight tickets

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How to get the cheapest flight ticket from Louisville to San Diego

What is the typical price of a round-trip flight between Louisville and San Diego?

What is the cheapest month to fly to San Diego?

How far in advance should I book a flight from Louisville to San Diego?

How have Louisville to San Diego flight prices changed over time?

What is the cheapest airline that flies from Louisville Intl to San Diego?

What airlines fly to San Diego?

When to book flights from Louisville to San Diego

Cheap Louisville to San Diego (SDF to SAN) flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Louisville to San Diego

Best airlines flying from Louisville to San Diego

Compare and see reviews for airlines that fly from Louisville to San Diego with momondo

Traveling to a place near San Diego?

Why use momondo?

An easier way to manage your San Diego trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing California

Fly your favorite airline to San Diego

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to San Diego

List of cabin classes available on flights landing in San Diego. Availability may vary depending on flight origin and airline.

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Popular flights according to clicks in the last 7 days on momondo

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