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Cheap flights from Louisville to San Diego from $143

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to San Diego departing on 3/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Louisville to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
3:33 pm - 8:36 pm
SDF
-
SAN
8h 03m
1 stop
American Airlines Logo
8:00 am - 5:37 pm
SAN
-
SDF
6h 37m
1 stop
$317American Airlines
Wed, Feb 11 - Tue, Feb 24
American Airlines Logo
6:00 am - 2:17 pm
SDF
-
SAN
11h 17m
1 stop
American Airlines Logo
1:03 pm - 11:30 pm
SAN
-
SDF
7h 27m
1 stop
$327American Airlines
Sat, Apr 25 - Tue, Apr 28
American Airlines Logo
10:49 am - 3:49 pm
SDF
-
SAN
8h 00m
1 stop
American Airlines Logo
10:43 pm - 9:51 am
SAN
-
SDF
8h 08m
1 stop
$338American Airlines
Tue, Feb 24 - Mon, Mar 2
United Airlines Logo
2:35 pm - 8:45 pm
SDF
-
SAN
9h 10m
1 stop
United Airlines Logo
11:03 am - 9:59 pm
SAN
-
SDF
7h 56m
2 stops
$343United Airlines
Mon, Mar 16 - Wed, Mar 18
American Airlines Logo
7:40 am - 3:57 pm
SDF
-
SAN
11h 17m
1 stop
American Airlines Logo
6:15 am - 7:03 pm
SAN
-
SDF
9h 48m
1 stop
$346American Airlines
Sat, Feb 7 - Sat, Feb 21
American Airlines Logo
10:31 am - 6:27 pm
SDF
-
SAN
10h 56m
1 stop
American Airlines Logo
10:35 pm - 11:30 am
SAN
-
SDF
9h 55m
1 stop
$349American Airlines
Tue, Feb 17 - Fri, Feb 20
American Airlines Logo
6:12 pm - 10:34 pm
SDF
-
SAN
7h 22m
1 stop
American Airlines Logo
1:37 pm - 12:27 am
SAN
-
SDF
7h 50m
1 stop
$359American Airlines
Mon, Feb 16 - Mon, Feb 23
United Airlines Logo
11:10 am - 5:28 pm
SDF
-
SAN
9h 18m
2 stops
United Airlines Logo
10:30 am - 9:46 pm
SAN
-
SDF
8h 16m
1 stop
$364United Airlines
Sat, Feb 7 - Sat, Feb 21
Delta Logo
5:35 pm - 11:09 pm
SDF
-
SAN
8h 34m
1 stop
Delta Logo
6:21 am - 5:15 pm
SAN
-
SDF
7h 54m
1 stop
$377Delta
Fri, Mar 13 - Wed, Mar 18
United Airlines Logo
5:35 am - 9:47 am
SDF
-
SAN
7h 12m
1 stop
United Airlines Logo
11:05 am - 10:37 pm
SAN
-
SDF
8h 32m
2 stops
$382United Airlines
Fri, Feb 20 - Tue, Feb 24

Southwest flights from Louisville to San Diego

Our best Southwest deals on Louisville to San Diego flight tickets
Southwest
Feb 20
SDF6:30 amLouisville Intl
9h 00m
2 stops
SAN12:30 pmSan Diego
Feb 24
SAN9:00 amSan Diego
11h 20m
2 stops
SDF11:20 pmLouisville Intl
$429
Southwest
Mar 5
SDF7:00 amLouisville Intl
6h 00m
1 stop
SAN10:00 amSan Diego
Mar 8
SAN9:35 pmSan Diego
9h 20m
2 stops
SDF9:55 amLouisville Intl
$442
Southwest
Jun 9
SDF1:00 pmLouisville Intl
8h 00m
2 stops
SAN6:00 pmSan Diego
Jun 16
SAN6:30 amSan Diego
9h 40m
2 stops
SDF7:10 pmLouisville Intl
$443

United Airlines flights from Louisville to San Diego

Our best United Airlines deals on Louisville to San Diego flight tickets
United Airlines
Mar 16
SDF2:35 pmLouisville Intl
9h 10m
1 stop
SAN8:45 pmSan Diego
Mar 18
SAN11:03 amSan Diego
7h 56m
2 stops
SDF9:59 pmLouisville Intl
$343
United Airlines
Feb 7
SDF11:10 amLouisville Intl
9h 18m
2 stops
SAN5:28 pmSan Diego
Feb 21
SAN10:30 amSan Diego
8h 16m
1 stop
SDF9:46 pmLouisville Intl
$364
United Airlines
Feb 20
SDF5:35 amLouisville Intl
7h 12m
1 stop
SAN9:47 amSan Diego
Feb 24
SAN11:05 amSan Diego
8h 32m
2 stops
SDF10:37 pmLouisville Intl
$382

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 18, 2026.
Use the filters below to find and compare flights from Louisville to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 2/11

3:33 pm-8:36 pm

1 stop8h 03m

San Diego

Tue 2/24

8:00 am-5:37 pm

1 stop6h 37m

$317

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Sat 4/25

6:00 am-2:17 pm

1 stop11h 17m

San Diego

Tue 4/28

1:03 pm-11:30 pm

1 stop7h 27m

$327

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 2/24

10:49 am-3:49 pm

1 stop8h 00m

San Diego

Mon 3/2

10:43 pm-9:51 am

1 stop8h 08m

$338

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Mon 3/16

2:35 pm-8:45 pm

1 stop9h 10m

San Diego

Wed 3/18

11:03 am-9:59 pm

2 stops7h 56m

$343

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Sat 2/7

7:40 am-3:57 pm

1 stop11h 17m

San Diego

Sat 2/21

6:15 am-7:03 pm

1 stop9h 48m

$346

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 2/17

10:31 am-6:27 pm

1 stop10h 56m

San Diego

Fri 2/20

10:35 pm-11:30 am

1 stop9h 55m

$349

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Mon 2/16

6:12 pm-10:34 pm

1 stop7h 22m

San Diego

Mon 2/23

1:37 pm-12:27 am

1 stop7h 50m

$359

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Sat 2/7

11:10 am-5:28 pm

2 stops9h 18m

San Diego

Sat 2/21

10:30 am-9:46 pm

1 stop8h 16m

$364

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Fri 3/13

5:35 pm-11:09 pm

1 stop8h 34m

San Diego

Wed 3/18

6:21 am-5:15 pm

1 stop7h 54m

$377

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Fri 2/20

5:35 am-9:47 am

1 stop7h 12m

San Diego

Tue 2/24

11:05 am-10:37 pm

2 stops8h 32m

$382

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Louisville to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Louisville and San Diego?

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of August, then departing from Louisville during the month September is also very affordable. Most momondo users find prices during this month for around $384.

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $431 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Louisville for as low as $347 on momondo.

How have Louisville to San Diego flight prices changed over time?

As of January 2026, prices for Louisville to San Diego flights are approximately 29% cheaper when compared to flights at the same time last year.

When to book flights from Louisville to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to San Diego (SDF to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to San Diego

Fastest flight time

6h 53m

Direct flights

None
The fastest flight from Louisville to San Diego takes 6h 53m
There are no direct flights from Louisville to San Diego. There are no popular flight routes from Louisville to San Diego.
Search flight deals

  • How far is Louisville Intl to San Diego by plane?

    The straight-line distance from Louisville Intl to San Diego is 1797.3 mi. Flights usually cover this in 6h 53m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Louisville Intl Airport to San Diego Airport?

    Prices for flights from Louisville Intl Airport to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Louisville Intl Airport to San Diego Airport?

  • How old do you have to be to fly from Louisville Intl Airport to San Diego Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Louisville to San Diego?

Best airlines flying from Louisville to San Diego

Compare and see reviews for airlines that fly from Louisville to San Diego with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $112Free CancellationRating
6.3
8,339 reviews
Search Spirit Airlines flights
DeltaPriceFrom $230Free CancellationRating
7.9
8,074 reviews
Search Delta flights
United AirlinesPriceFrom $260Free CancellationRating
7.4
9,174 reviews
Search United Airlines flights
American AirlinesPriceFrom $292Free CancellationRating
7.2
11,156 reviews
Search American Airlines flights
SouthwestPriceFrom $336Free CancellationRating
8.0
4,261 reviews
Search Southwest flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
Poway
National City
Imperial Beach
Borrego Springs
San Ysidro
La Mesa
Alpine
Lemon Grove
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Louisville to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Louisville to San Diego with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Diego from Louisville with this policy.

How can momondo help me find flights from Louisville to San Diego?

momondo helps you find the best flight between Louisville and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Louisville to San Diego right now. Can momondo alert me if prices change?

Price alerts on flights to San Diego from Louisville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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