Cheap flights from Louisville to San Diego from $190

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to San Diego departing on 1/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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American Airlines Logo
8:13 pm - 11:59 pmSDF-SAN
6h 46m1 stop
American Airlines Logo
6:15 am - 9:24 pmSAN-SDF
12h 09m1 stop
$243American Airlines
Find Deal
Sun, Feb 15 - Tue, Feb 17
American Airlines Logo
6:32 pm - 10:50 pmSDF-SAN
7h 18m1 stop
American Airlines Logo
6:20 am - 11:19 pmSAN-SDF
13h 59m1 stop
$280American Airlines
Find Deal
Tue, Jan 13 - Tue, Jan 20
Delta Logo
4:56 pm - 8:51 pmSDF-SAN
6h 55m1 stop
Delta Logo
10:00 pm - 10:01 amSAN-SDF
9h 01m1 stop
$285Delta
Find Deal
Tue, Jan 13 - Sat, Jan 17
United Airlines Logo
9:50 am - 5:28 pmSDF-SAN
10h 38m2 stops
United Airlines Logo
12:11 pm - 9:59 pmSAN-SDF
6h 48m1 stop
$289United Airlines
Find Deal
Tue, Jan 13 - Tue, Jan 20
American Airlines Logo
7:00 am - 12:44 pmSDF-SAN
8h 44m1 stop
American Airlines Logo
10:45 pm - 10:24 amSAN-SDF
8h 39m1 stop
$293American Airlines
Find Deal
Mon, Jan 5 - Tue, Jan 13
Southwest Logo
12:50 pm - 6:40 pmSDF-SAN
8h 50m2 stops
Southwest Logo
9:40 am - 9:10 pmSAN-SDF
8h 30m2 stops
$294Southwest
Find Deal
Tue, Jan 20 - Tue, Jan 27
American Airlines Logo
10:48 am - 3:48 pmSDF-SAN
8h 00m1 stop
American Airlines Logo
10:09 am - 8:47 pmSAN-SDF
7h 38m2 stops
$298American Airlines
Find Deal
Mon, Jan 5 - Tue, Jan 13
Delta Logo
6:23 am - 10:48 amSDF-SAN
7h 25m1 stop
Delta Logo
10:30 pm - 9:28 amSAN-SDF
7h 58m1 stop
$299Delta
Find Deal
Tue, Jan 13 - Sat, Jan 17
American Airlines Logo
8:12 pm - 11:59 pmSDF-SAN
6h 47m1 stop
American Airlines Logo
6:15 am - 6:21 pmSAN-SDF
9h 06m1 stop
$303American Airlines
Find Deal
Thu, Dec 18 - Thu, Dec 25
Southwest Logo
6:00 am - 12:25 pmSDF-SAN
9h 25m2 stops
Southwest Logo
7:05 am - 5:10 pmSAN-SDF
7h 05m1 stop
$304Southwest
Find Deal
Wed, Feb 11 - Sun, Feb 15

American Airlines flights from Louisville to San Diego

Our best American Airlines deals on Louisville to San Diego flight tickets
American Airlines
Feb 15
SDF8:13 pmLouisville Intl
6h 46m
1 stop
SAN11:59 pmSan Diego
Feb 17
SAN6:15 amSan Diego
12h 09m
1 stop
SDF9:24 pmLouisville Intl
American Airlines
Jan 5
SDF7:00 amLouisville Intl
8h 44m
1 stop
SAN12:44 pmSan Diego
Jan 13
SAN10:45 pmSan Diego
8h 39m
1 stop
SDF10:24 amLouisville Intl
American Airlines
Jan 5
SDF10:48 amLouisville Intl
8h 00m
1 stop
SAN3:48 pmSan Diego
Jan 13
SAN10:09 amSan Diego
7h 38m
2 stops
SDF8:47 pmLouisville Intl

Delta flights from Louisville to San Diego

Our best Delta deals on Louisville to San Diego flight tickets
Delta
Jan 13
SDF4:56 pmLouisville Intl
6h 55m
1 stop
SAN8:51 pmSan Diego
Jan 17
SAN10:00 pmSan Diego
9h 01m
1 stop
SDF10:01 amLouisville Intl
Delta
Jan 13
SDF6:23 amLouisville Intl
7h 25m
1 stop
SAN10:48 amSan Diego
Jan 17
SAN10:30 pmSan Diego
7h 58m
1 stop
SDF9:28 amLouisville Intl
Delta
Dec 9
SDF7:26 pmLouisville Intl
7h 18m
1 stop
SAN11:44 pmSan Diego
Dec 11
SAN10:00 pmSan Diego
9h 04m
1 stop
SDF10:04 amLouisville Intl

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 20, 2025.
Use the filters below to find and compare flights from Louisville to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Sun 2/15

8:13 pm-11:59 pm

1 stop6h 46m

San Diego

Tue 2/17

6:15 am-9:24 pm

1 stop12h 09m

$243

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 1/13

6:32 pm-10:50 pm

1 stop7h 18m

San Diego

Tue 1/20

6:20 am-11:19 pm

1 stop13h 59m

$280

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 1/13

4:56 pm-8:51 pm

1 stop6h 55m

San Diego

Sat 1/17

10:00 pm-10:01 am

1 stop9h 01m

$285

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 1/13

9:50 am-5:28 pm

2 stops10h 38m

San Diego

Tue 1/20

12:11 pm-9:59 pm

1 stop6h 48m

$289

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Mon 1/5

7:00 am-12:44 pm

1 stop8h 44m

San Diego

Tue 1/13

10:45 pm-10:24 am

1 stop8h 39m

$293

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 1/20

12:50 pm-6:40 pm

2 stops8h 50m

San Diego

Tue 1/27

9:40 am-9:10 pm

2 stops8h 30m

$294

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Mon 1/5

10:48 am-3:48 pm

1 stop8h 00m

San Diego

Tue 1/13

10:09 am-8:47 pm

2 stops7h 38m

$298

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 1/13

6:23 am-10:48 am

1 stop7h 25m

San Diego

Sat 1/17

10:30 pm-9:28 am

1 stop7h 58m

$299

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Thu 12/18

8:12 pm-11:59 pm

1 stop6h 47m

San Diego

Thu 12/25

6:15 am-6:21 pm

1 stop9h 06m

$303

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 2/11

6:00 am-12:25 pm

2 stops9h 25m

San Diego

Sun 2/15

7:05 am-5:10 pm

1 stop7h 05m

$304

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Louisville to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of August, then departing from Louisville during the month September is also very affordable. Most momondo users find prices during this month for around $384.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Louisville to San Diego is on a Wednesday. Travelers who choose to depart for San Diego on a Wednesday will often find tickets for as low as $416. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $505. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is in the evening when flights can be purchased for as low as $393. Flights at noon are often more expensive with an average ticket price of $520.

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $446 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Louisville for as low as $347 on momondo.

How have Louisville to San Diego flight prices changed over time?

As of November 2025, prices for Louisville to San Diego flights are approximately 129% more expensive when compared to flights at the same time last year.

When to book flights from Louisville to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to San Diego (SDF to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to San Diego

Direct flights

None
There are no direct flights from Louisville to San Diego. There are no popular flight routes from Louisville to San Diego.
  • How far is Louisville Intl to San Diego by plane?

    The straight-line distance from Louisville Intl to San Diego is 1797.3 mi. Flights usually cover this in 6h 46m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Louisville Intl Airport to San Diego Airport?

    Prices for flights from Louisville Intl Airport to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Louisville Intl Airport to San Diego Airport?

  • How old do you have to be to fly from Louisville Intl Airport to San Diego Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Louisville to San Diego?

Best airlines flying from Louisville to San Diego

Compare and see reviews for airlines that fly from Louisville to San Diego with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $232Free CancellationRating
6.3
8,159 reviews
Search Spirit Airlines flights
United AirlinesPriceFrom $274Free CancellationRating
7.4
9,028 reviews
Search United Airlines flights
DeltaPriceFrom $276Free CancellationRating
7.9
8,002 reviews
Search Delta flights
American AirlinesPriceFrom $303Free CancellationRating
7.2
11,047 reviews
Search American Airlines flights
SouthwestPriceFrom $362Free CancellationRating
8.0
4,251 reviews
Search Southwest flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
Imperial Beach
La Mesa
Poway
Borrego Springs
San Ysidro
Lemon Grove
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Louisville to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Louisville to San Diego with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Diego from Louisville with this policy.

How can momondo help me find flights from Louisville to San Diego?

momondo helps you find the best flight between Louisville and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Louisville to San Diego right now. Can momondo alert me if prices change?

Price alerts on flights to San Diego from Louisville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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1 adult
Sat 12/20
Sat 12/27

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