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Cheap flights from Louisville to San Diego from $141

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to San Diego departing on 4/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:48 pm - 5:59 pm
SDF
-
SAN
49h 11m
2 stops
Multiple Airlines Logo
12:54 pm - 8:36 am
SAN
-
SDF
16h 42m
1 stop
$277Multiple Airlines
ma., mai 4 - ti., mai 19
Breeze Airways Logo
6:55 pm - 11:48 am
SDF
-
SAN
19h 53m
1 stop
Breeze Airways Logo
12:54 pm - 8:36 am
SAN
-
SDF
16h 42m
1 stop
$303Breeze Airways
to., mai 7 - ti., mai 19
Breeze Airways Logo
6:55 pm - 11:48 am
SDF
-
SAN
19h 53m
1 stop
Breeze Airways Logo
12:54 pm - 8:36 am
SAN
-
SDF
16h 42m
1 stop
$309Breeze Airways
to., mai 7 - ti., mai 19
Multiple Airlines Logo
9:21 am - 12:43 pm
SDF
-
SAN
30h 22m
2 stops
Multiple Airlines Logo
12:54 pm - 8:36 am
SAN
-
SDF
16h 42m
1 stop
$311Multiple Airlines
on., mai 6 - ti., mai 19
Multiple Airlines Logo
6:55 pm - 11:48 am
SDF
-
SAN
19h 53m
1 stop
Multiple Airlines Logo
6:25 am - 11:34 am
SAN
-
SDF
26h 09m
2 stops
$313Multiple Airlines
to., mai 7 - ti., mai 19
Breeze Airways Logo
6:55 pm - 11:48 am
SDF
-
SAN
19h 53m
1 stop
Breeze Airways Logo
12:54 pm - 8:36 am
SAN
-
SDF
16h 42m
1 stop
$314Breeze Airways
sø., mai 10 - ti., mai 19
Breeze Airways Logo
6:55 pm - 11:48 am
SDF
-
SAN
19h 53m
1 stop
Breeze Airways Logo
12:54 pm - 8:36 am
SAN
-
SDF
16h 42m
1 stop
$315Breeze Airways
to., mai 7 - ti., mai 12
Multiple Airlines Logo
6:06 pm - 6:25 pm
SDF
-
SAN
27h 19m
2 stops
Multiple Airlines Logo
12:54 pm - 8:36 am
SAN
-
SDF
16h 42m
1 stop
$320Multiple Airlines
fr., mai 8 - ti., mai 19
United Airlines Logo
3:30 pm - 8:05 pm
SDF
-
SAN
7h 35m
1 stop
United Airlines Logo
10:30 pm - 9:10 am
SAN
-
SDF
7h 40m
1 stop
$321United Airlines
on., apr. 1 - ti., apr. 7
Multiple Airlines Logo
6:55 pm - 11:48 am
SDF
-
SAN
19h 53m
1 stop
Multiple Airlines Logo
4:17 pm - 7:26 pm
SAN
-
SDF
24h 09m
2 stops
$322Multiple Airlines
to., mai 7 - ti., mai 19

Breeze Airways flights from Louisville to San Diego

Our best Breeze Airways deals on Louisville to San Diego flight tickets
Breeze Airways
May 7
SDF6:55 pmLouisville Intl
19h 53m
1 stop
SAN11:48 amSan Diego
May 19
SAN12:54 pmSan Diego
16h 42m
1 stop
SDF8:36 amLouisville Intl
$303
Breeze Airways
May 7
SDF6:55 pmLouisville Intl
19h 53m
1 stop
SAN11:48 amSan Diego
May 19
SAN12:54 pmSan Diego
16h 42m
1 stop
SDF8:36 amLouisville Intl
$309
Breeze Airways
May 10
SDF6:55 pmLouisville Intl
19h 53m
1 stop
SAN11:48 amSan Diego
May 19
SAN12:54 pmSan Diego
16h 42m
1 stop
SDF8:36 amLouisville Intl
$314

Delta flights from Louisville to San Diego

Our best Delta deals on Louisville to San Diego flight tickets
Delta
May 5
SDF6:04 amLouisville Intl
7h 39m
1 stop
SAN10:43 amSan Diego
May 18
SAN10:15 pmSan Diego
8h 44m
1 stop
SDF9:59 amLouisville Intl
$353
Delta
May 8
SDF8:10 amLouisville Intl
7h 28m
1 stop
SAN12:38 pmSan Diego
May 18
SAN10:25 pmSan Diego
7h 31m
1 stop
SDF8:56 amLouisville Intl
$415
Delta
May 5
SDF7:25 pmLouisville Intl
7h 13m
1 stop
SAN11:38 pmSan Diego
May 20
SAN6:15 amSan Diego
14h 37m
2 stops
SDF11:52 pmLouisville Intl
$423

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated mars 15, 2026.
Use the filters below to find and compare flights from Louisville to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

ma. 5/4

7:48 pm-5:59 pm

2 stops49h 11m

San Diego

ti. 5/19

12:54 pm-8:36 am

1 stop16h 42m

$277

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

to. 5/7

6:55 pm-11:48 am

1 stop19h 53m

San Diego

ti. 5/19

12:54 pm-8:36 am

1 stop16h 42m

$303

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

to. 5/7

6:55 pm-11:48 am

1 stop19h 53m

San Diego

ti. 5/19

12:54 pm-8:36 am

1 stop16h 42m

$309

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

on. 5/6

9:21 am-12:43 pm

2 stops30h 22m

San Diego

ti. 5/19

12:54 pm-8:36 am

1 stop16h 42m

$311

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

to. 5/7

6:55 pm-11:48 am

1 stop19h 53m

San Diego

ti. 5/19

6:25 am-11:34 am

2 stops26h 09m

$313

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

sø. 5/10

6:55 pm-11:48 am

1 stop19h 53m

San Diego

ti. 5/19

12:54 pm-8:36 am

1 stop16h 42m

$314

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

to. 5/7

6:55 pm-11:48 am

1 stop19h 53m

San Diego

ti. 5/12

12:54 pm-8:36 am

1 stop16h 42m

$315

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

fr. 5/8

6:06 pm-6:25 pm

2 stops27h 19m

San Diego

ti. 5/19

12:54 pm-8:36 am

1 stop16h 42m

$320
Quickest round-trip

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

on. 4/1

3:30 pm-8:05 pm

1 stop7h 35m

San Diego

ti. 4/7

10:30 pm-9:10 am

1 stop7h 40m

$321

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

to. 5/7

6:55 pm-11:48 am

1 stop19h 53m

San Diego

ti. 5/19

4:17 pm-7:26 pm

2 stops24h 09m

$322

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Louisville to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of August, then departing from Louisville during the month January is also very affordable. Most momondo users find prices during this month for around $383.

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $428 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Louisville for as low as $347 on momondo.

How have Louisville to San Diego flight prices changed over time?

As of March 2026, prices for Louisville to San Diego flights are approximately 10% more expensive when compared to flights at the same time last year.

When to book flights from Louisville to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to San Diego (SDF to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to San Diego

Fastest flight time

6h 20m

Direct flights

None
The fastest flight from Louisville to San Diego takes 6h 20m
There are no direct flights from Louisville to San Diego. There are no popular flight routes from Louisville to San Diego.
Search flight deals

  • How far is Louisville Intl to San Diego by plane?

    The straight-line distance from Louisville Intl to San Diego is 1797.3 mi. Flights usually cover this in 6h 20m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Louisville Intl Airport to San Diego Airport?

    Prices for flights from Louisville Intl Airport to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Louisville Intl Airport to San Diego Airport?

  • How old do you have to be to fly from Louisville Intl Airport to San Diego Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Louisville to San Diego?

Best airlines flying from Louisville to San Diego

Compare and see reviews for airlines that fly from Louisville to San Diego with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $112Free CancellationRating
6.3
8,516 reviews
Search Spirit Airlines flights
DeltaPriceFrom $230Free CancellationRating
7.9
8,293 reviews
Search Delta flights
United AirlinesPriceFrom $260Free CancellationRating
7.4
9,427 reviews
Search United Airlines flights
American AirlinesPriceFrom $284Free CancellationRating
7.1
11,472 reviews
Search American Airlines flights
SouthwestPriceFrom $336Free CancellationRating
8.0
4,318 reviews
Search Southwest flights

  • Southwest Flights From Louisville to San Diego

    Southwest is one of the most popular airlines flying from Louisville to San Diego, operating 3 flights/week on average for this route. A good Southwest flight deal for Louisville to San Diego starts from $336 round-trip, up to an average price of $459. Our users have rated Southwest at 8.0/10.

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
Poway
San Ysidro
Imperial Beach
La Mesa
Borrego Springs
Alpine
Santee
Lemon Grove

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Louisville to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Louisville to San Diego with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Diego from Louisville with this policy.

How can momondo help me find flights from Louisville to San Diego?

momondo helps you find the best flight between Louisville and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Louisville to San Diego right now. Can momondo alert me if prices change?

Price alerts on flights to San Diego from Louisville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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