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Cheap flights from Louisville to San Diego from $133

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Louisville to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
8:47 am - 6:16 pmSDF  Louisville Intl-SAN San Diego
12h 29m1 stop San Francisco
Multiple Airlines Logo
7:51 pm - 7:19 pmSAN  San Diego-SDF Louisville Intl
20h 28m1 stop San Francisco
$247Multiple Airlines
Mon, Dec 7 - Thu, Dec 10
Multiple Airlines Logo
8:47 am - 6:16 pmSDF  Louisville Intl-SAN San Diego
12h 29m1 stop San Francisco
Multiple Airlines Logo
1:22 pm - 4:32 pmSAN  San Diego-SDF Louisville Intl
24h 10m1 stop Raleigh-Durham
$275Multiple Airlines
Mon, Dec 7 - Tue, Dec 8
American Airlines Logo
6:24 am - 10:59 amSDF  Louisville Intl-SAN San Diego
7h 35m1 stop Chicago O'Hare Intl
American Airlines Logo
7:15 am - 4:26 pmSAN  San Diego-SDF Louisville Intl
6h 11m1 stop Dallas/Fort Worth
$283American Airlines
Tue, Dec 1 - Sat, Dec 5
Delta Logo
7:05 am - 1:08 pmSDF  Louisville Intl-SAN San Diego
9h 03m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:20 am - 4:53 pmSAN  San Diego-SDF Louisville Intl
7h 33m1 stop Atlanta Hartsfield-Jackson
$283Delta
Mon, Nov 23 - Wed, Dec 2
American Airlines Logo
6:30 pm - 11:47 pmSDF  Louisville Intl-SAN San Diego
8h 17m1 stop Chicago O'Hare Intl
American Airlines Logo
8:00 am - 6:25 pmSAN  San Diego-SDF Louisville Intl
7h 25m1 stop Dallas/Fort Worth
$294American Airlines
Tue, Dec 1 - Tue, Dec 8
Delta Logo
7:05 am - 11:54 amSDF  Louisville Intl-SAN San Diego
7h 49m1 stop Atlanta Hartsfield-Jackson
Delta Logo
10:30 pm - 10:47 amSAN  San Diego-SDF Louisville Intl
9h 17m1 stop Detroit Metropolitan Wayne County
$302Delta
Mon, Dec 14 - Mon, Dec 21
Southwest Logo
3:50 pm - 7:10 pmSDF  Louisville Intl-SAN San Diego
6h 20m1 stop Las Vegas Harry Reid Intl
Southwest Logo
10:35 pm - 10:50 amSAN  San Diego-SDF Louisville Intl
9h 15m1 stop Chicago Midway
$321Southwest
Sat, Feb 6 - Sat, Feb 13
Southwest Logo
7:15 pm - 1:30 amSDF  Louisville Intl-SAN San Diego
9h 15m1 stop Nashville Intl
Southwest Logo
6:30 am - 3:35 pmSAN  San Diego-SDF Louisville Intl
6h 05m1 stop Chicago Midway
$321Southwest
Tue, Dec 22 - Fri, Dec 25
United Airlines Logo
3:20 pm - 8:41 pmSDF  Louisville Intl-SAN San Diego
8h 21m1 stop Denver Intl
United Airlines Logo
6:45 am - 6:17 pmSAN  San Diego-SDF Louisville Intl
8h 32m2 stops Denver Intl Chicago O'Hare Intl
$326United Airlines
Mon, Dec 7 - Wed, Dec 9
United Airlines Logo
5:57 pm - 10:40 pmSDF  Louisville Intl-SAN San Diego
7h 43m1 stop Chicago O'Hare Intl
United Airlines Logo
10:30 pm - 9:44 amSAN  San Diego-SDF Louisville Intl
8h 14m1 stop Chicago O'Hare Intl
$359United Airlines
Sat, Nov 21 - Wed, Nov 25

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United Airlines flights from Louisville to San Diego

Our best United Airlines deals on Louisville to San Diego flight tickets
United Airlines
Jan 8
SDF8:50 amLouisville Intl
9h 05m
2 stops
SAN2:55 pmSan Diego
Jan 17
SAN12:39 pmSan Diego
6h 51m
1 stop
SDF10:30 pmLouisville Intl
$368
United Airlines
Nov 16
SDF9:02 amLouisville Intl
11h 15m
2 stops
SAN5:17 pmSan Diego
Nov 19
SAN6:20 amSan Diego
13h 04m
2 stops
SDF10:24 pmLouisville Intl
$470
United Airlines
Nov 12
SDF9:55 amLouisville Intl
8h 33m
1 stop
SAN3:28 pmSan Diego
Nov 12
SAN9:45 pmSan Diego
9h 49m
1 stop
SDF10:34 amLouisville Intl
$517

Delta flights from Louisville to San Diego

Our best Delta deals on Louisville to San Diego flight tickets
Delta
Nov 23
SDF7:05 amLouisville Intl
9h 03m
1 stop
SAN1:08 pmSan Diego
Dec 2
SAN6:20 amSan Diego
7h 33m
1 stop
SDF4:53 pmLouisville Intl
$283
Delta
Dec 12
SDF7:41 amLouisville Intl
9h 47m
1 stop
SAN2:28 pmSan Diego
Dec 22
SAN10:30 pmSan Diego
9h 17m
1 stop
SDF10:47 amLouisville Intl
$302
Delta
Dec 8
SDF6:35 amLouisville Intl
9h 27m
1 stop
SAN1:02 pmSan Diego
Dec 8
SAN10:10 pmSan Diego
9h 09m
1 stop
SDF10:19 amLouisville Intl
$321

momondo Fare Finder

 
Use the filters below to find and compare flights from Louisville to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Mon 12/7

8:47 am-6:16 pm

1 stop12h 29m

San Diego

Thu 12/10

7:51 pm-7:19 pm

1 stop20h 28m

$247

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Mon 12/7

8:47 am-6:16 pm

1 stop12h 29m

San Diego

Tue 12/8

1:22 pm-4:32 pm

1 stop24h 10m

$275
Quickest round-trip

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Tue 12/1

6:24 am-10:59 am

1 stop7h 35m

San Diego

Sat 12/5

7:15 am-4:26 pm

1 stop6h 11m

$283

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Mon 11/23

7:05 am-1:08 pm

1 stop9h 03m

San Diego

Wed 12/2

6:20 am-4:53 pm

1 stop7h 33m

$283

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Tue 12/1

6:30 pm-11:47 pm

1 stop8h 17m

San Diego

Tue 12/8

8:00 am-6:25 pm

1 stop7h 25m

$294

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Mon 12/14

7:05 am-11:54 am

1 stop7h 49m

San Diego

Mon 12/21

10:30 pm-10:47 am

1 stop9h 17m

$302

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Sat 2/6

3:50 pm-7:10 pm

1 stop6h 20m

San Diego

Sat 2/13

10:35 pm-10:50 am

1 stop9h 15m

$321

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Tue 12/22

7:15 pm-1:30 am

1 stop9h 15m

San Diego

Fri 12/25

6:30 am-3:35 pm

1 stop6h 05m

$321

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Mon 12/7

3:20 pm-8:41 pm

1 stop8h 21m

San Diego

Wed 12/9

6:45 am-6:17 pm

2 stops8h 32m

$326

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Sat 11/21

5:57 pm-10:40 pm

1 stop7h 43m

San Diego

Wed 11/25

10:30 pm-9:44 am

1 stop8h 14m

$359

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Louisville to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Louisville and San Diego?

Prices are currently low for flights on this route.

Typical prices usually range from $322 to $486.
The lowest price recently found on this route was $247.

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of February, then departing from Louisville during the month November is also very affordable. Most momondo users find prices during this month for around $393.

How far in advance should I book a flight from Louisville to San Diego?

You are more likely to see cheaper flights to San Diego from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $452 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Louisville for as low as $375 on momondo.

How have Louisville to San Diego flight prices changed over time?

As of November 2026, prices for Louisville to San Diego flights are approximately 34% more expensive when compared to flights at the same time last year.

When to book flights from Louisville to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to San Diego (SDF to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to San Diego

Best Price Found

$133

Fastest flight time

6h 05m

Direct flights

None
The best one-way flight to San Diego from Louisville in the past 72 hours is $133. The best round-trip flight deal from Louisville to San Diego found on momondo in the last 72 hours is $247.
The fastest flight from Louisville to San Diego takes 6h 05m
There are no direct flights from Louisville to San Diego. There are no popular flight routes from Louisville to San Diego.
Search flight deals

Frequently asked questions about flying from Louisville to San Diego

  • How far is Louisville Intl to San Diego by plane?

    The straight-line distance from Louisville Intl to San Diego is 1797.3 mi. Flights usually cover this in 6h 05m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Louisville Intl Airport to San Diego Airport?

    Prices for flights from Louisville Intl Airport to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Louisville Intl Airport to San Diego Airport?

  • How old do you have to be to fly from Louisville Intl Airport to San Diego Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Louisville to San Diego?

Best airlines flying from Louisville to San Diego

Compare and see reviews for airlines that fly from Louisville to San Diego with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $278Free CancellationRating
7.8
8,696 reviews
Search Delta flights
American AirlinesPriceFrom $312Free CancellationRating
7.0
12,230 reviews
Search American Airlines flights
United AirlinesPriceFrom $322Free CancellationRating
7.3
10,460 reviews
Search United Airlines flights
SouthwestPriceFrom $332Free CancellationRating
8.0
4,215 reviews
Search Southwest flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Chula Vista
El Cajon
Coronado
National City
La Mesa
Julian
San Ysidro
Poway
Santee
Alpine
Imperial Beach
Lemon Grove
Borrego Springs

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Louisville to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Louisville to San Diego with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Diego from Louisville with this policy.

How can momondo help me find flights from Louisville to San Diego?

momondo helps you find the best flight between Louisville and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Louisville to San Diego right now. Can momondo alert me if prices change?

Price alerts on flights to San Diego from Louisville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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