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Cheap flights from Louisville to San Diego from $122

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to San Diego departing on 12/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
1:32 pm - 10:26 pmSDF-SAN
11h 54m1 stop
American Airlines Logo
6:15 am - 9:24 pmSAN-SDF
12h 09m1 stop
$243American Airlines
Find Deal
mié., feb. 11 - mar., feb. 24
American Airlines Logo
1:32 pm - 10:26 pmSDF-SAN
11h 54m1 stop
American Airlines Logo
6:20 am - 11:19 pmSAN-SDF
13h 59m1 stop
$258American Airlines
Find Deal
jue., ene. 15 - dom., ene. 18
Delta Logo
12:57 pm - 6:20 pmSDF-SAN
8h 23m1 stop
Delta Logo
12:16 pm - 11:00 pmSAN-SDF
7h 44m1 stop
$289Delta
Find Deal
lun., nov. 24 - jue., nov. 27
United Airlines Logo
9:00 am - 3:04 pmSDF-SAN
9h 04m2 stops
United Airlines Logo
12:50 pm - 10:09 pmSAN-SDF
6h 19m1 stop
$296United Airlines
Find Deal
sáb., dic. 13 - mar., dic. 16
Delta Logo
3:32 pm - 8:37 pmSDF-SAN
8h 05m1 stop
Delta Logo
6:15 am - 6:11 pmSAN-SDF
8h 56m1 stop
$306Delta
Find Deal
mié., ene. 28 - sáb., ene. 31
Southwest Logo
7:55 am - 5:55 pmSDF-SAN
13h 00m2 stops
Southwest Logo
10:30 am - 9:30 pmSAN-SDF
8h 00m2 stops
$307Southwest
Find Deal
sáb., dic. 13 - mar., dic. 16
United Airlines Logo
9:00 am - 3:04 pmSDF-SAN
9h 04m2 stops
United Airlines Logo
10:52 am - 8:28 pmSAN-SDF
6h 36m1 stop
$333United Airlines
Find Deal
mié., dic. 10 - sáb., dic. 13
Southwest Logo
12:50 pm - 6:40 pmSDF-SAN
8h 50m2 stops
Southwest Logo
6:25 am - 6:00 pmSAN-SDF
8h 35m2 stops
$352Southwest
Find Deal
jue., ene. 22 - dom., ene. 25
Alaska Airlines Logo
1:46 pm - 11:07 pmSDF-SAN
12h 21m2 stops
Alaska Airlines Logo
7:58 pm - 6:39 pmSAN-SDF
19h 41m2 stops
$421Alaska Airlines
Find Deal
mié., dic. 24 - mié., ene. 7
Alaska Airlines Logo
11:16 am - 10:07 amSDF-SAN
25h 51m2 stops
Alaska Airlines Logo
7:03 pm - 9:16 pmSAN-SDF
23h 13m2 stops
$428Alaska Airlines
Find Deal
mié., ene. 28 - sáb., ene. 31

Delta flights from Louisville to San Diego

Our best Delta deals on Louisville to San Diego flight tickets
Delta
Nov 24
SDF12:57 pmLouisville Intl
8h 23m
1 stop
SAN6:20 pmSan Diego
Nov 27
SAN12:16 pmSan Diego
7h 44m
1 stop
SDF11:00 pmLouisville Intl
$289
Find similar
Delta
Jan 28
SDF3:32 pmLouisville Intl
8h 05m
1 stop
SAN8:37 pmSan Diego
Jan 31
SAN6:15 amSan Diego
8h 56m
1 stop
SDF6:11 pmLouisville Intl
$306
Find similar
Delta
Jan 28
SDF6:23 amLouisville Intl
7h 25m
1 stop
SAN10:48 amSan Diego
Jan 31
SAN11:43 amSan Diego
6h 41m
1 stop
SDF9:24 pmLouisville Intl
$323
Find similar

Alaska Airlines flights from Louisville to San Diego

Our best Alaska Airlines deals on Louisville to San Diego flight tickets
Alaska Airlines
Dec 24
SDF1:46 pmLouisville Intl
12h 21m
2 stops
SAN11:07 pmSan Diego
Jan 7
SAN7:58 pmSan Diego
19h 41m
2 stops
SDF6:39 pmLouisville Intl
$421
Find similar
Alaska Airlines
Jan 28
SDF11:16 amLouisville Intl
25h 51m
2 stops
SAN10:07 amSan Diego
Jan 31
SAN7:03 pmSan Diego
23h 13m
2 stops
SDF9:16 pmLouisville Intl
$428
Find similar
Alaska Airlines
Nov 5
SDF6:44 amLouisville Intl
15h 28m
2 stops
SAN7:12 pmSan Diego
Nov 11
SAN7:00 amSan Diego
12h 01m
2 stops
SDF10:01 pmLouisville Intl
$773
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated octubre 30, 2025.
Use the filters below to find and compare flights from Louisville to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

mié. 2/11

1:32 pm-10:26 pm

1 stop11h 54m

San Diego

mar. 2/24

6:15 am-9:24 pm

1 stop12h 09m

$243

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

jue. 1/15

1:32 pm-10:26 pm

1 stop11h 54m

San Diego

dom. 1/18

6:20 am-11:19 pm

1 stop13h 59m

$258

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

lun. 11/24

12:57 pm-6:20 pm

1 stop8h 23m

San Diego

jue. 11/27

12:16 pm-11:00 pm

1 stop7h 44m

$289

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

sáb. 12/13

9:00 am-3:04 pm

2 stops9h 04m

San Diego

mar. 12/16

12:50 pm-10:09 pm

1 stop6h 19m

$296

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

mié. 1/28

3:32 pm-8:37 pm

1 stop8h 05m

San Diego

sáb. 1/31

6:15 am-6:11 pm

1 stop8h 56m

$306

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

sáb. 12/13

7:55 am-5:55 pm

2 stops13h 00m

San Diego

mar. 12/16

10:30 am-9:30 pm

2 stops8h 00m

$307

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

mié. 12/10

9:00 am-3:04 pm

2 stops9h 04m

San Diego

sáb. 12/13

10:52 am-8:28 pm

1 stop6h 36m

$333

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

jue. 1/22

12:50 pm-6:40 pm

2 stops8h 50m

San Diego

dom. 1/25

6:25 am-6:00 pm

2 stops8h 35m

$352

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

mié. 12/24

1:46 pm-11:07 pm

2 stops12h 21m

San Diego

mié. 1/7

7:58 pm-6:39 pm

2 stops19h 41m

$421

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

mié. 1/28

11:16 am-10:07 am

2 stops25h 51m

San Diego

sáb. 1/31

7:03 pm-9:16 pm

2 stops23h 13m

$428

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Louisville to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of August, then departing from Louisville during the month September is also very affordable. Most momondo users find prices during this month for around $384.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Louisville to San Diego is on a Wednesday. Travelers who choose to depart for San Diego on a Wednesday will often find tickets for as low as $416. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $505. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is in the evening when flights can be purchased for as low as $393. Flights at noon are often more expensive with an average ticket price of $520.

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $456 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Louisville for as low as $364 on momondo.

How have Louisville to San Diego flight prices changed over time?

As of October 2025, prices for Louisville to San Diego flights are approximately 22% cheaper when compared to flights at the same time last year.

When to book flights from Louisville to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to San Diego (SDF to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to San Diego

Direct flights

None
There are no direct flights from Louisville to San Diego. There are no popular flight routes from Louisville to San Diego.
Search flight deals

  • How far is Louisville Intl to San Diego by plane?

    The straight-line distance from Louisville Intl to San Diego is 1797.3 mi. Flights usually cover this in 6h 47m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Louisville Intl Airport to San Diego Airport?

    Prices for flights from Louisville Intl Airport to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Louisville Intl Airport to San Diego Airport?

  • How old do you have to be to fly from Louisville Intl Airport to San Diego Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Louisville to San Diego?

Best airlines flying from Louisville to San Diego

Compare and see reviews for airlines that fly from Louisville to San Diego with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $232Free CancellationRating
6.3
8,116 reviews
Search Spirit Airlines flights
United AirlinesPriceFrom $274Free CancellationRating
7.4
8,998 reviews
Search United Airlines flights
DeltaPriceFrom $276Free CancellationRating
7.9
7,998 reviews
Search Delta flights
American AirlinesPriceFrom $306Free CancellationRating
7.2
11,035 reviews
Search American Airlines flights
SouthwestPriceFrom $362Free CancellationRating
8.0
4,243 reviews
Search Southwest flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
La Mesa
Imperial Beach
Poway
Borrego Springs
San Ysidro
Lemon Grove
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Louisville to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Louisville to San Diego with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Diego from Louisville with this policy.

How can momondo help me find flights from Louisville to San Diego?

momondo helps you find the best flight between Louisville and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Louisville to San Diego right now. Can momondo alert me if prices change?

Price alerts on flights to San Diego from Louisville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your San Diego trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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1 adult
sáb. 11/29
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