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Cheap flights from Louisville to San Diego from $161

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to San Diego departing on 8/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Louisville to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
3:33 pm - 9:10 pm
SDF
-
SAN
8h 37m
1 stop
Delta Logo
11:53 am - 11:48 pm
SAN
-
SDF
8h 55m
1 stop
$321Delta
Tue, Sep 22 - Tue, Sep 29
Southwest Logo
8:15 am - 12:05 pm
SDF
-
SAN
6h 50m
1 stop
Southwest Logo
2:30 pm - 11:05 pm
SAN
-
SDF
5h 35m
1 stop
$324Southwest
Wed, Aug 26 - Mon, Aug 31
Delta Logo
6:49 am - 10:43 am
SDF
-
SAN
6h 54m
1 stop
Delta Logo
2:18 pm - 12:26 am
SAN
-
SDF
7h 08m
1 stop
$325Delta
Wed, Jul 1 - Tue, Jul 7
American Airlines Logo
7:50 pm - 11:59 pm
SDF
-
SAN
7h 09m
1 stop
American Airlines Logo
10:45 pm - 10:03 am
SAN
-
SDF
8h 18m
1 stop
$326American Airlines
Wed, Jul 8 - Tue, Jul 21
Delta Logo
6:00 am - 9:36 am
SDF
-
SAN
6h 36m
1 stop
Delta Logo
6:15 am - 4:40 pm
SAN
-
SDF
7h 25m
1 stop
$329Delta
Tue, Sep 22 - Sat, Sep 26
Southwest Logo
1:15 pm - 6:40 pm
SDF
-
SAN
8h 25m
2 stops
Southwest Logo
2:30 pm - 11:05 pm
SAN
-
SDF
5h 35m
1 stop
$330Southwest
Wed, Aug 26 - Mon, Aug 31
Southwest Logo
1:15 pm - 6:55 pm
SDF
-
SAN
8h 40m
2 stops
Southwest Logo
6:40 am - 6:30 pm
SAN
-
SDF
8h 50m
1 stop
$334Southwest
Wed, Sep 23 - Mon, Sep 28
American Airlines Logo
7:10 pm - 11:26 pm
SDF
-
SAN
7h 16m
1 stop
American Airlines Logo
10:45 pm - 10:03 am
SAN
-
SDF
8h 18m
1 stop
$335American Airlines
Tue, Jul 7 - Tue, Jul 21
American Airlines Logo
7:30 pm - 11:59 pm
SDF
-
SAN
7h 29m
1 stop
American Airlines Logo
8:00 am - 6:50 pm
SAN
-
SDF
7h 50m
1 stop
$337American Airlines
Thu, Sep 3 - Thu, Sep 10
Southwest Logo
4:00 pm - 9:05 pm
SDF
-
SAN
8h 05m
2 stops
Southwest Logo
8:30 am - 10:35 pm
SAN
-
SDF
11h 05m
2 stops
$339Southwest
Wed, Aug 26 - Mon, Aug 31

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United Airlines flights from Louisville to San Diego

Our best United Airlines deals on Louisville to San Diego flight tickets
United Airlines
Sep 13
SDF6:00 amLouisville Intl
8h 25m
1 stop
SAN11:25 amSan Diego
Sep 19
SAN12:04 pmSan Diego
7h 11m
1 stop
SDF10:15 pmLouisville Intl
$397
United Airlines
Sep 1
SDF9:45 amLouisville Intl
6h 32m
1 stop
SAN1:17 pmSan Diego
Sep 2
SAN12:33 pmSan Diego
6h 58m
1 stop
SDF10:31 pmLouisville Intl
$421
United Airlines
Sep 22
SDF3:25 pmLouisville Intl
8h 09m
1 stop
SAN8:34 pmSan Diego
Sep 29
SAN7:41 pmSan Diego
10h 56m
2 stops
SDF9:37 amLouisville Intl
$426

Delta flights from Louisville to San Diego

Our best Delta deals on Louisville to San Diego flight tickets
Delta
Sep 22
SDF3:33 pmLouisville Intl
8h 37m
1 stop
SAN9:10 pmSan Diego
Sep 29
SAN11:53 amSan Diego
8h 55m
1 stop
SDF11:48 pmLouisville Intl
$321
Delta
Jul 1
SDF6:49 amLouisville Intl
6h 54m
1 stop
SAN10:43 amSan Diego
Jul 7
SAN2:18 pmSan Diego
7h 08m
1 stop
SDF12:26 amLouisville Intl
$325
Delta
Sep 22
SDF6:00 amLouisville Intl
6h 36m
1 stop
SAN9:36 amSan Diego
Sep 28
SAN2:00 pmSan Diego
6h 59m
1 stop
SDF11:59 pmLouisville Intl
$329

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 17, 2026.
Use the filters below to find and compare flights from Louisville to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 9/22

3:33 pm-9:10 pm

1 stop8h 37m

San Diego

Tue 9/29

11:53 am-11:48 pm

1 stop8h 55m

$321
Quickest round-trip

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 8/26

8:15 am-12:05 pm

1 stop6h 50m

San Diego

Mon 8/31

2:30 pm-11:05 pm

1 stop5h 35m

$324

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 7/1

6:49 am-10:43 am

1 stop6h 54m

San Diego

Tue 7/7

2:18 pm-12:26 am

1 stop7h 08m

$325

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 7/8

7:50 pm-11:59 pm

1 stop7h 09m

San Diego

Tue 7/21

10:45 pm-10:03 am

1 stop8h 18m

$326

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 9/22

6:00 am-9:36 am

1 stop6h 36m

San Diego

Sat 9/26

6:15 am-4:40 pm

1 stop7h 25m

$329

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 8/26

1:15 pm-6:40 pm

2 stops8h 25m

San Diego

Mon 8/31

2:30 pm-11:05 pm

1 stop5h 35m

$330

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 9/23

1:15 pm-6:55 pm

2 stops8h 40m

San Diego

Mon 9/28

6:40 am-6:30 pm

1 stop8h 50m

$334

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 7/7

7:10 pm-11:26 pm

1 stop7h 16m

San Diego

Tue 7/21

10:45 pm-10:03 am

1 stop8h 18m

$335

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Thu 9/3

7:30 pm-11:59 pm

1 stop7h 29m

San Diego

Thu 9/10

8:00 am-6:50 pm

1 stop7h 50m

$337

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Wed 8/26

4:00 pm-9:05 pm

2 stops8h 05m

San Diego

Mon 8/31

8:30 am-10:35 pm

2 stops11h 05m

$339

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Louisville to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Louisville and San Diego?

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of August, then departing from Louisville during the month February is also very affordable. Most momondo users find prices during this month for around $378.

How far in advance should I book a flight from Louisville to San Diego?

You are more likely to see cheaper flights to San Diego from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $436 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Louisville for as low as $333 on momondo.

How have Louisville to San Diego flight prices changed over time?

As of June 2026, prices for Louisville to San Diego flights are approximately 24% more expensive when compared to flights at the same time last year.

When to book flights from Louisville to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to San Diego (SDF to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to San Diego

Fastest flight time

7h 09m

Direct flights

None
The fastest flight from Louisville to San Diego takes 7h 09m
There are no direct flights from Louisville to San Diego. There are no popular flight routes from Louisville to San Diego.
Search flight deals

Frequently asked questions about flying from Louisville to San Diego

  • How far is Louisville Intl to San Diego by plane?

    The straight-line distance from Louisville Intl to San Diego is 1797.3 mi. Flights usually cover this in 7h 09m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Louisville Intl Airport to San Diego Airport?

    Prices for flights from Louisville Intl Airport to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Louisville Intl Airport to San Diego Airport?

  • How old do you have to be to fly from Louisville Intl Airport to San Diego Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Louisville to San Diego?

Best airlines flying from Louisville to San Diego

Compare and see reviews for airlines that fly from Louisville to San Diego with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $260Free CancellationRating
7.4
9,845 reviews
Search United Airlines flights
DeltaPriceFrom $276Free CancellationRating
7.8
8,406 reviews
Search Delta flights
American AirlinesPriceFrom $282Free CancellationRating
7.1
11,670 reviews
Search American Airlines flights
SouthwestPriceFrom $332Free CancellationRating
7.9
4,235 reviews
Search Southwest flights

  • Southwest Flights From Louisville to San Diego

    Southwest is one of the most popular airlines flying from Louisville to San Diego, operating 2 flights/week on average for this route. A good Southwest flight deal for Louisville to San Diego starts from $332 round-trip, up to an average price of $463. Our users have rated Southwest at 7.9/10.

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Chula Vista
Coronado
El Cajon
Julian
National City
Poway
La Mesa
San Ysidro
Borrego Springs
Imperial Beach
Lemon Grove
Santee
Alpine

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Louisville to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Louisville to San Diego with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Diego from Louisville with this policy.

How can momondo help me find flights from Louisville to San Diego?

momondo helps you find the best flight between Louisville and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Louisville to San Diego right now. Can momondo alert me if prices change?

Price alerts on flights to San Diego from Louisville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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