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Cheap flights from Louisville to San Diego from $133

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to San Diego departing on 8/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Louisville to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
2:56 pm - 11:24 amSDF  Louisville Intl-SAN San Diego
23h 28m1 stop Raleigh-Durham
Multiple Airlines Logo
6:25 am - 2:16 pmSAN  San Diego-SDF Louisville Intl
28h 51m2 stops Denver Intl Raleigh-Durham
$274Multiple Airlines
Wed, Aug 26 - Tue, Sep 1
Multiple Airlines Logo
2:56 pm - 11:24 amSDF  Louisville Intl-SAN San Diego
23h 28m1 stop Raleigh-Durham
Multiple Airlines Logo
3:45 pm - 2:16 pmSAN  San Diego-SDF Louisville Intl
43h 31m2 stops Denver Intl Raleigh-Durham
$275Multiple Airlines
Wed, Aug 26 - Mon, Aug 31
American Airlines Logo
5:59 pm - 11:25 pmSDF  Louisville Intl-SAN San Diego
8h 26m1 stop Chicago O'Hare Intl
American Airlines Logo
6:18 am - 4:37 pmSAN  San Diego-SDF Louisville Intl
7h 19m1 stop Chicago O'Hare Intl
$299American Airlines
Sat, Oct 3 - Wed, Oct 7
American Airlines Logo
6:00 am - 10:25 amSDF  Louisville Intl-SAN San Diego
7h 25m1 stop Dallas/Fort Worth
American Airlines Logo
12:58 pm - 11:22 pmSAN  San Diego-SDF Louisville Intl
7h 24m1 stop Charlotte Douglas
$299American Airlines
Tue, Sep 15 - Sat, Sep 19
Southwest Logo
7:10 pm - 11:00 pmSDF  Louisville Intl-SAN San Diego
6h 50m1 stop Chicago Midway
Southwest Logo
6:20 am - 3:40 pmSAN  San Diego-SDF Louisville Intl
6h 20m1 stop Houston Hobby
$300Southwest
Thu, Sep 24 - Mon, Sep 28
Southwest Logo
7:35 pm - 11:20 pmSDF  Louisville Intl-SAN San Diego
6h 45m1 stop Chicago Midway
Southwest Logo
3:00 pm - 11:40 pmSAN  San Diego-SDF Louisville Intl
5h 40m1 stop Phoenix Sky Harbor Intl
$300Southwest
Thu, Nov 19 - Mon, Nov 23
United Airlines Logo
5:15 am - 9:32 amSDF  Louisville Intl-SAN San Diego
7h 17m1 stop Chicago O'Hare Intl
United Airlines Logo
11:00 am - 10:29 pmSAN  San Diego-SDF Louisville Intl
8h 29m1 stop Denver Intl
$317United Airlines
Thu, Sep 3 - Tue, Sep 15
Delta Logo
10:32 am - 2:09 pmSDF  Louisville Intl-SAN San Diego
6h 37m1 stop Detroit Metropolitan Wayne County
Delta Logo
11:54 am - 11:43 pmSAN  San Diego-SDF Louisville Intl
8h 49m1 stop Minneapolis St Paul
$317Delta
Tue, Sep 8 - Tue, Sep 15
Delta Logo
7:55 am - 2:09 pmSDF  Louisville Intl-SAN San Diego
9h 14m1 stop Detroit Metropolitan Wayne County
Delta Logo
6:25 am - 3:49 pmSAN  San Diego-SDF Louisville Intl
6h 24m1 stop Minneapolis St Paul
$317Delta
Tue, Sep 8 - Sat, Sep 12
United Airlines Logo
1:50 pm - 7:55 pmSDF  Louisville Intl-SAN San Diego
9h 05m2 stops Chicago O'Hare Intl Los Angeles
United Airlines Logo
10:40 am - 8:32 pmSAN  San Diego-SDF Louisville Intl
6h 52m1 stop Chicago O'Hare Intl
$339United Airlines
Sat, Sep 5 - Sat, Sep 12

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American Airlines flights from Louisville to San Diego

Our best American Airlines deals on Louisville to San Diego flight tickets
American Airlines
Sep 15
SDF6:00 amLouisville Intl
7h 25m
1 stop
SAN10:25 amSan Diego
Sep 19
SAN12:58 pmSan Diego
7h 24m
1 stop
SDF11:22 pmLouisville Intl
$299
American Airlines
Oct 7
SDF5:19 pmLouisville Intl
9h 14m
1 stop
SAN11:33 pmSan Diego
Oct 14
SAN10:40 pmSan Diego
7h 52m
1 stop
SDF9:32 amLouisville Intl
$304
American Airlines
Sep 3
SDF7:30 pmLouisville Intl
7h 29m
1 stop
SAN11:59 pmSan Diego
Sep 10
SAN6:15 amSan Diego
8h 04m
1 stop
SDF5:19 pmLouisville Intl
$335

Delta flights from Louisville to San Diego

Our best Delta deals on Louisville to San Diego flight tickets
Delta
Sep 8
SDF10:32 amLouisville Intl
6h 37m
1 stop
SAN2:09 pmSan Diego
Sep 15
SAN11:54 amSan Diego
8h 49m
1 stop
SDF11:43 pmLouisville Intl
$317
Delta
Sep 29
SDF8:09 amLouisville Intl
7h 16m
1 stop
SAN12:25 pmSan Diego
Oct 2
SAN2:00 pmSan Diego
6h 59m
1 stop
SDF11:59 pmLouisville Intl
$341
Delta
Jan 18
SDF5:45 pmLouisville Intl
8h 18m
1 stop
SAN11:03 pmSan Diego
Jan 23
SAN6:15 amSan Diego
8h 25m
1 stop
SDF5:40 pmLouisville Intl
$347

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 11, 2026.
Use the filters below to find and compare flights from Louisville to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Wed 8/26

2:56 pm-11:24 am

1 stop23h 28m

San Diego

Tue 9/1

6:25 am-2:16 pm

2 stops28h 51m

$274

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Wed 8/26

2:56 pm-11:24 am

1 stop23h 28m

San Diego

Mon 8/31

3:45 pm-2:16 pm

2 stops43h 31m

$275

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Sat 10/3

5:59 pm-11:25 pm

1 stop8h 26m

San Diego

Wed 10/7

6:18 am-4:37 pm

1 stop7h 19m

$299

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Tue 9/15

6:00 am-10:25 am

1 stop7h 25m

San Diego

Sat 9/19

12:58 pm-11:22 pm

1 stop7h 24m

$299

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Thu 9/24

7:10 pm-11:00 pm

1 stop6h 50m

San Diego

Mon 9/28

6:20 am-3:40 pm

1 stop6h 20m

$300
Quickest round-trip

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Thu 11/19

7:35 pm-11:20 pm

1 stop6h 45m

San Diego

Mon 11/23

3:00 pm-11:40 pm

1 stop5h 40m

$300

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Thu 9/3

5:15 am-9:32 am

1 stop7h 17m

San Diego

Tue 9/15

11:00 am-10:29 pm

1 stop8h 29m

$317

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Tue 9/8

10:32 am-2:09 pm

1 stop6h 37m

San Diego

Tue 9/15

11:54 am-11:43 pm

1 stop8h 49m

$317

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Tue 9/8

7:55 am-2:09 pm

1 stop9h 14m

San Diego

Sat 9/12

6:25 am-3:49 pm

1 stop6h 24m

$317

LouisvilleSan Diego

SDF Louisville Intl - SAN San Diego

SDFSAN

Louisville Intl

Sat 9/5

1:50 pm-7:55 pm

2 stops9h 05m

San Diego

Sat 9/12

10:40 am-8:32 pm

1 stop6h 52m

$339

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Louisville to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Louisville and San Diego?

Prices are currently typical for flights on this route.

Typical prices usually range from $276 to $466.
The lowest price recently found on this route was $276.

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of February, then departing from Louisville during the month August is also very affordable. Most momondo users find prices during this month for around $389.

How far in advance should I book a flight from Louisville to San Diego?

You are more likely to see cheaper flights to San Diego from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $444 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Louisville for as low as $333 on momondo.

How have Louisville to San Diego flight prices changed over time?

As of August 2026, prices for Louisville to San Diego flights are approximately 124% more expensive when compared to flights at the same time last year.

When to book flights from Louisville to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to San Diego (SDF to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to San Diego

Fastest flight time

6h 45m

Direct flights

None
The fastest flight from Louisville to San Diego takes 6h 45m
There are no direct flights from Louisville to San Diego. There are no popular flight routes from Louisville to San Diego.
Search flight deals

Frequently asked questions about flying from Louisville to San Diego

  • How far is Louisville Intl to San Diego by plane?

    The straight-line distance from Louisville Intl to San Diego is 1797.3 mi. Flights usually cover this in 6h 45m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Louisville Intl Airport to San Diego Airport?

    Prices for flights from Louisville Intl Airport to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Louisville Intl Airport to San Diego Airport?

  • How old do you have to be to fly from Louisville Intl Airport to San Diego Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Louisville to San Diego?

Best airlines flying from Louisville to San Diego

Compare and see reviews for airlines that fly from Louisville to San Diego with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $260Free CancellationRating
7.4
10,103 reviews
Search United Airlines flights
DeltaPriceFrom $276Free CancellationRating
7.8
8,505 reviews
Search Delta flights
American AirlinesPriceFrom $282Free CancellationRating
7.1
11,902 reviews
Search American Airlines flights
SouthwestPriceFrom $341Free CancellationRating
8.0
4,221 reviews
Search Southwest flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Chula Vista
Coronado
El Cajon
National City
Julian
La Mesa
Poway
San Ysidro
Imperial Beach
Santee
Borrego Springs
Lemon Grove
Alpine

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Louisville to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Louisville to San Diego with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Diego from Louisville with this policy.

How can momondo help me find flights from Louisville to San Diego?

momondo helps you find the best flight between Louisville and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Louisville to San Diego right now. Can momondo alert me if prices change?

Price alerts on flights to San Diego from Louisville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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