Cheap flights from Knoxville to San Diego from $104
This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to San Diego departing on 8/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
Discover deals from 900+ travel sites with momondo.
Save money when you book flights with momondo
Big names and deals
Big names and deals
Search 100s of travel sites to compare prices.Filter for what you want
Filter for what you want
Free Wi-Fi? Stopover? Instantly customize your results.Trusted and free
Trusted and free
We’re completely free to use - no hidden charges or fees.Price Alerts
Price Alerts
Not ready to book? to track prices.Find the cheapest flights from Knoxville to San Diego
Cheap round-trip flights
Cheap one-way flights
Cheap last minute flights
Delta flights from Knoxville to San Diego
Our best Delta deals on Knoxville to San Diego flight tickets
United Airlines flights from Knoxville to San Diego
Our best United Airlines deals on Knoxville to San Diego flight tickets
See travel insights to San Diego from
How to get the cheapest flight ticket from Knoxville to San Diego
Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip
What is the cheapest month to fly to San Diego?
If you are unable to visit San Diego during the month of January, then departing from Knoxville during the month February is also very affordable. Most momondo users find prices during this month for around $313.
What is the cheapest day to depart on your flight to San Diego?
The cheapest day to depart from Knoxville to San Diego is on a Wednesday. Travelers who choose to depart for San Diego on a Wednesday will often find tickets for as low as $388. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $584. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.
What is the cheapest time of day to depart on your flight to San Diego?
The cheapest time of day to fly to San Diego is in the evening when flights can be purchased for as low as $346. Flights in the morning are often more expensive with an average ticket price of $413.
How far in advance should I book a flight to San Diego?
You are more likely to see cheaper flights to San Diego from Knoxville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $397 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Knoxville for as low as $341 on momondo.
What is the cheapest airline that flies from Knoxville McGhee Tyson to San Diego?
Frontier, Delta, and American Airlines are the most popular carriers operating from Knoxville McGhee Tyson to San Diego
What airlines fly to San Diego?
American Airlines, Delta and United Airlines are the top three most popular airlines that fly to San Diego from Knoxville according to our data. American Airlines is the first choice among our users, with 71% of people opting to fly with this airline when traveling to San Diego. Keep in mind that there are 5 different airlines that fly to San Diego on a routine basis, so you have a few additional options to choose from.
When to book flights from Knoxville to San Diego
Cheap Knoxville to San Diego (TYS to SAN) flight deals and tips
Find info about flight duration, direct flights, and airports for your flight from Knoxville to San Diego
How far is Knoxville McGhee Tyson to San Diego by plane?
There are 1898.9 mi between Knoxville McGhee Tyson and San Diego. A reasonable flight in good conditions will take 6h 23m.
When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to San Diego Airport?
Prices for flights from Knoxville McGhee Tyson Airport to San Diego Airport are updated daily.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to San Diego Airport?
The number of operators available for flights from Knoxville McGhee Tyson Airport to San Diego Airport is 5 as of June 2025.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to San Diego Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to San Diego Airport.
What documentation or ID do you need to fly to San Diego Airport?
The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Knoxville to San Diego?
Based on momondo bookings for flights between Knoxville and San Diego, the leading airline is American Airlines, making up 64% of the total bookings. Other popular airlines include Delta with 20%, United Airlines with 10%, and Frontier with 3%.
Best airlines flying from Knoxville to San Diego
Compare and see reviews for airlines that fly from Knoxville to San Diego with momondo
| Airline | Rating | Free Cancellation | Price | ||
|---|---|---|---|---|---|
| PriceFrom $150 | Free Cancellation | Rating 5.9 3,296 reviews | |||
| PriceFrom $258 | Free Cancellation | Rating 7.4 8,840 reviews | |||
| PriceFrom $263 | Free Cancellation | Rating 7.2 10,000 reviews | |||
| PriceFrom $276 | Free Cancellation | Rating 8.0 7,966 reviews | |||
| PriceFrom $366 | Free Cancellation | Rating 8.0 10,000 reviews |
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsWhy use momondo?
Why should I use momondo to find a flight deal from Knoxville to San Diego?
We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Knoxville to San Diego for you.
Can I find flights from Knoxville to San Diego with flexible booking policies on momondo?
Flights from Knoxville to San Diego with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.
How can momondo help me find flights from Knoxville to San Diego?
Once you have performed a search for Knoxville to San Diego flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.
I’m not ready to book a flight from Knoxville to San Diego right now. Can momondo alert me if prices change?
Yes. momondo can track prices for Knoxville to San Diego flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.