What airlines fly to Key West?

Allegiant Air, American Airlines and Delta are the top three most popular airlines that fly to Key West from Knoxville according to our data. Allegiant Air is the first choice among our users, with 82% of people opting to fly with this airline when traveling to Key West. Keep in mind that there are 3 different airlines that fly to Key West on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Knoxville McGhee Tyson to Key West?

Allegiant Air is the most popular carrier operating from Knoxville McGhee Tyson to Key West

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Key West Airport?

Prices for flights from Knoxville McGhee Tyson Airport to Key West Airport refresh daily.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Key West Airport?

As of September 2026, there are 2 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Key West Airport.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Key West Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Key West Airport.

What documentation or ID do you need to fly to Key West Airport?

The required travel and health documents for your Key West Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Key West Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$47 Cheap Flights from Knoxville to Key West in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Key West

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

9:00 am - 11:04 amTYS Knoxville McGhee Tyson-EYW Key West

2h 04mnonstop

9:54 am - 12:07 pmEYW Key West-TYS Knoxville McGhee Tyson

2h 13mnonstop

$82Allegiant Air

Mon, Oct 19 - Fri, Oct 23

9:00 am - 11:04 amTYS Knoxville McGhee Tyson-EYW Key West

2h 04mnonstop

9:54 am - 12:07 pmEYW Key West-TYS Knoxville McGhee Tyson

2h 13mnonstop

$84Allegiant Air

Mon, Oct 19 - Fri, Oct 23

9:00 am - 11:04 amTYS Knoxville McGhee Tyson-EYW Key West

2h 04mnonstop

9:54 am - 12:07 pmEYW Key West-TYS Knoxville McGhee Tyson

2h 13mnonstop

$88Allegiant Air

Mon, Oct 19 - Fri, Oct 23

7:00 am - 9:04 amTYS Knoxville McGhee Tyson-EYW Key West

2h 04mnonstop

11:09 am - 1:22 pmEYW Key West-TYS Knoxville McGhee Tyson

2h 13mnonstop

$96Allegiant Air

Fri, Oct 30 - Mon, Nov 2

9:41 pm - 9:24 amTYS Knoxville McGhee Tyson-EYW Key West

11h 43m1 stop Tampa St. Petersburg

11:09 am - 1:22 pmEYW Key West-TYS Knoxville McGhee Tyson

2h 13mnonstop

$145Multiple Airlines

Fri, Oct 30 - Mon, Nov 2

11:00 am - 1:14 pmTYS Knoxville McGhee Tyson-EYW Key West

2h 14mnonstop

12:59 pm - 10:43 amEYW Key West-TYS Knoxville McGhee Tyson

21h 44m1 stop Tampa

$184Multiple Airlines

Mon, Jan 11 - Fri, Jan 15

9:00 am - 11:04 amTYS Knoxville McGhee Tyson-EYW Key West

2h 04mnonstop

10:59 am - 9:44 amEYW Key West-TYS Knoxville McGhee Tyson

46h 45m2 stops Orlando Washington, D.C. Dulles Intl

$189Multiple Airlines

Mon, Oct 19 - Fri, Oct 23

4:15 pm - 10:43 pmTYS Knoxville McGhee Tyson-EYW Key West

6h 28m1 stop Charlotte Douglas

4:40 pm - 11:52 pmEYW Key West-TYS Knoxville McGhee Tyson

7h 12m1 stop Charlotte Douglas

$339American Airlines

Fri, Feb 26 - Tue, Mar 2

5:57 pm - 10:43 pmTYS Knoxville McGhee Tyson-EYW Key West

4h 46m1 stop Charlotte Douglas

4:40 pm - 10:00 pmEYW Key West-TYS Knoxville McGhee Tyson

5h 20m1 stop Charlotte Douglas

$339American Airlines

Fri, Feb 26 - Tue, Mar 2

6:20 am - 1:35 pmTYS Knoxville McGhee Tyson-EYW Key West

7h 15m1 stop Charlotte Douglas

5:28 pm - 10:59 pmEYW Key West-TYS Knoxville McGhee Tyson

5h 31m1 stop Miami

$339American Airlines

Tue, Oct 13 - Tue, Oct 20

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Allegiant Air flights from Knoxville to Key West

Our best Allegiant Air deals on Knoxville to Key West flight tickets

Allegiant Air

Oct 19

TYS9:00 amKnoxville McGhee Tyson

2h 04m

EYW11:04 amKey West

Oct 23

EYW9:54 amKey West

2h 13m

TYS12:07 pmKnoxville McGhee Tyson

$82

Allegiant Air

Oct 19

TYS9:00 amKnoxville McGhee Tyson

2h 04m

EYW11:04 amKey West

Oct 23

EYW9:54 amKey West

2h 13m

TYS12:07 pmKnoxville McGhee Tyson

$84

Allegiant Air

Oct 19

TYS9:00 amKnoxville McGhee Tyson

2h 04m

EYW11:04 amKey West

Oct 23

EYW9:54 amKey West

2h 13m

TYS12:07 pmKnoxville McGhee Tyson

$88

American Airlines flights from Knoxville to Key West

Our best American Airlines deals on Knoxville to Key West flight tickets

American Airlines

Sep 26

TYS6:05 amKnoxville McGhee Tyson

4h 55m

1 stop

EYW11:00 amKey West

Sep 29

EYW6:27 pmKey West

4h 23m

1 stop

TYS10:50 pmKnoxville McGhee Tyson

$369

American Airlines

Sep 26

TYS6:05 amKnoxville McGhee Tyson

4h 55m

1 stop

EYW11:00 amKey West

Sep 29

EYW1:47 pmKey West

7h 19m

2 stops

TYS9:06 pmKnoxville McGhee Tyson

$523

American Airlines

Sep 29

TYS8:18 amKnoxville McGhee Tyson

10h 59m

2 stops

EYW7:17 pmKey West

Oct 3

EYW11:30 amKey West

9h 36m

2 stops

TYS9:06 pmKnoxville McGhee Tyson

$643

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

KnoxvilleKey West

TYS Knoxville McGhee Tyson - EYW Key West

TYSEYW

Knoxville McGhee Tyson

Mon 10/19

9:00 am-11:04 am

Nonstop2h 04m

Key West

Fri 10/23

9:54 am-12:07 pm

Nonstop2h 13m

$82

KnoxvilleKey West

TYS Knoxville McGhee Tyson - EYW Key West

TYSEYW

Knoxville McGhee Tyson

Mon 10/19

9:00 am-11:04 am

Nonstop2h 04m

Key West

Fri 10/23

9:54 am-12:07 pm

Nonstop2h 13m

$84

KnoxvilleKey West

TYS Knoxville McGhee Tyson - EYW Key West

TYSEYW

Knoxville McGhee Tyson

Mon 10/19

9:00 am-11:04 am

Nonstop2h 04m

Key West

Fri 10/23

9:54 am-12:07 pm

Nonstop2h 13m

$88

KnoxvilleKey West

TYS Knoxville McGhee Tyson - EYW Key West

TYSEYW

Knoxville McGhee Tyson

Fri 10/30

7:00 am-9:04 am

Nonstop2h 04m

Key West

Mon 11/2

11:09 am-1:22 pm

Nonstop2h 13m

$96

KnoxvilleKey West

TYS Knoxville McGhee Tyson - EYW Key West

TYSEYW

Knoxville McGhee Tyson

Fri 10/30

9:41 pm-9:24 am

1 stop11h 43m

Key West

Mon 11/2

11:09 am-1:22 pm

Nonstop2h 13m

$145

KnoxvilleKey West

TYS Knoxville McGhee Tyson - EYW Key West

TYSEYW

Knoxville McGhee Tyson

Mon 1/11

11:00 am-1:14 pm

Nonstop2h 14m

Key West

Fri 1/15

12:59 pm-10:43 am

1 stop21h 44m

$184

KnoxvilleKey West

TYS Knoxville McGhee Tyson - EYW Key West

TYSEYW

Knoxville McGhee Tyson

Mon 10/19

9:00 am-11:04 am

Nonstop2h 04m

Key West

Fri 10/23

10:59 am-9:44 am

2 stops46h 45m

$189

KnoxvilleKey West

TYS Knoxville McGhee Tyson - EYW Key West

TYSEYW

Knoxville McGhee Tyson

Fri 2/26

4:15 pm-10:43 pm

1 stop6h 28m

Key West

Tue 3/2

4:40 pm-11:52 pm

1 stop7h 12m

$339

KnoxvilleKey West

TYS Knoxville McGhee Tyson - EYW Key West

TYSEYW

Knoxville McGhee Tyson

Fri 2/26

5:57 pm-10:43 pm

1 stop4h 46m

Key West

Tue 3/2

4:40 pm-10:00 pm

1 stop5h 20m

$339

KnoxvilleKey West

TYS Knoxville McGhee Tyson - EYW Key West

TYSEYW

Knoxville McGhee Tyson

Tue 10/13

6:20 am-1:35 pm

1 stop7h 15m

Key West

Tue 10/20

5:28 pm-10:59 pm

1 stop5h 31m

$339

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Key West?

In general, August is the cheapest month to fly from Knoxville to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $84. If you are unable to visit Key West during the month of August, then departing from Knoxville during the month June is also very affordable. Most momondo users find prices during this month for around $128.

What is the cheapest day to depart on your flight to Key West?

On average, the least expensive day to fly to Key West from Knoxville is on a Monday. momondo users have found tickets for Monday departures for as low as $105. However, this price may fluctuate depending on the airline, the season, and holidays. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Knoxville to Key West for around $208.

What is the cheapest time of day to depart on your flight to Key West?

According to our data, the cheapest time of day to fly to Key West is in the afternoon. momondo users have found flights departing from Knoxville to Key West in the afternoon for as low as $95. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Key West are more costly in the morning, with an average ticket price of $143. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Knoxville McGhee Tyson to Key West flight route?

Fly from Knoxville McGhee Tyson to Key West for the best Knoxville McGhee Tyson - Key West flight prices

How far in advance should I book a flight from Knoxville to Key West?

You are more likely to see cheaper flights to Key West from Knoxville when booking weeks ahead of your departure date. In general, you can expect to find flights to Key West for around $186 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Key West from Knoxville for as low as $109 on momondo.

What cabin class options are available on Knoxville to Key West flights?

There is only 1 cabin class available to choose from on Knoxville to Key West flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

When to book flights from Knoxville to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Key West according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Knoxville to Key West (TYS to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Key West

Best Price Found	$47
Fastest flight time	2h 04m
Direct flights	Tue, Thu, Sat and Sun
Airports in Key West	1 airport

The best one-way flight to Key West from Knoxville in the past 72 hours is $47. The best round-trip flight deal from Knoxville to Key West found on momondo in the last 72 hours is $82.

The fastest flight from Knoxville to Key West takes 2h 04m

Direct flights go from Knoxville to Key West on Tuesday, Thursday, Saturday and Sunday. There are no airlines offering direct flights.

There is 1 airport in Key West. From Knoxville there are direct flights to Key West (EYW).

Search flight deals

Frequently asked questions about flying from Knoxville to Key West

How far is Knoxville McGhee Tyson to Key West by plane?
Knoxville McGhee Tyson and Key West are 797.5 mi apart from one another. Typically, this will take 2h 04m by plane in normal conditions.
When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Key West Airport?
Prices for flights from Knoxville McGhee Tyson Airport to Key West Airport refresh daily.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Key West Airport?
As of September 2026, there are 2 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Key West Airport.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Key West Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Key West Airport.
What documentation or ID do you need to fly to Key West Airport?
The required travel and health documents for your Key West Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Key West Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Knoxville to Key West?
Based on momondo bookings for flights between Knoxville and Key West, the leading plane model is Airbus A320-100/200, making up 82.22% of the total bookings. Other popular models include Airbus A319 with 8.89%, Boeing 737 MAX 8 with 4.44%, and Embraer 175 with 4.44%.
What is the most popular airline from Knoxville to Key West?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Knoxville to Key West is Allegiant Air (88% of total bookings). The next most popular airline is American Airlines (12%).

Best airlines flying from Knoxville to Key West

Compare and see reviews for airlines that fly from Knoxville to Key West with momondo

Airline	Rating	Free Cancellation	Price
Allegiant Air	PriceFrom $71	Free Cancellation	Rating 7.3 679 reviews		Search Allegiant Air flights
American Airlines	PriceFrom $250	Free Cancellation	Rating 7.1 12,078 reviews		Search American Airlines flights

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Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Key West?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Key West from Knoxville.

Can I find flights from Knoxville to Key West with flexible booking policies on momondo?

Flights from Knoxville to Key West with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Knoxville to Key West?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Knoxville to Key West.

I’m not ready to book a flight from Knoxville to Key West right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Knoxville to Key West flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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Cheap flights from Knoxville to Key West from $47

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Key West departing on 10/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Allegiant Air flights from Knoxville to Key West

Our best Allegiant Air deals on Knoxville to Key West flight tickets

American Airlines flights from Knoxville to Key West

Our best American Airlines deals on Knoxville to Key West flight tickets

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How to get the cheapest flight ticket from Knoxville to Key West

What is the cheapest month to fly to Key West?

What is the cheapest day to depart on your flight to Key West?

What is the cheapest time of day to depart on your flight to Key West?

What is the cheapest Knoxville McGhee Tyson to Key West flight route?

How far in advance should I book a flight from Knoxville to Key West?

What cabin class options are available on Knoxville to Key West flights?

What is the cheapest airline that flies from Knoxville McGhee Tyson to Key West?

What airlines fly to Key West?

When to book flights from Knoxville to Key West

Cheap Knoxville to Key West (TYS to EYW) flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Airports in Key West

Frequently asked questions about flying from Knoxville to Key West

Best airlines flying from Knoxville to Key West

Compare and see reviews for airlines that fly from Knoxville to Key West with momondo

Traveling to a place near Key West?

Why use momondo?

An easier way to manage your Key West trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing Florida

Fly your favorite airline to Key West

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Key West

List of cabin classes available on flights landing in Key West. Availability may vary depending on flight origin and airline.

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