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Cheap flights from Knoxville to Chicago from $63

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Chicago departing on 6/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
1:22 pm - 1:58 pm
TYS
-
MDW
1h 36mnonstop
Allegiant Air Logo
2:48 pm - 5:18 pm
MDW
-
TYS
1h 30mnonstop
$220Allegiant Air
Thu, Jul 16 - Sun, Jul 19
Allegiant Air Logo
1:22 pm - 1:58 pm
TYS
-
MDW
1h 36mnonstop
Allegiant Air Logo
2:48 pm - 5:18 pm
MDW
-
TYS
1h 30mnonstop
$231Allegiant Air
Thu, Jul 16 - Thu, Jul 23
Allegiant Air Logo
1:22 pm - 1:58 pm
TYS
-
MDW
1h 36mnonstop
Allegiant Air Logo
2:48 pm - 5:18 pm
MDW
-
TYS
1h 30mnonstop
$233Allegiant Air
Thu, Jul 23 - Sun, Jul 26
Allegiant Air Logo
9:00 am - 8:21 am
TYS
-
MDW
24h 21m
1 stop
Allegiant Air Logo
2:46 pm - 5:14 pm
MDW
-
TYS
1h 28mnonstop
$242Allegiant Air
Sat, Jun 6 - Thu, Jun 11
Multiple Airlines Logo
1:15 pm - 10:14 pm
TYS
-
MDW
33h 59m
2 stops
Multiple Airlines Logo
9:14 am - 5:30 pm
MDW
-
TYS
7h 16m
1 stop
$243Multiple Airlines
Mon, Apr 20 - Mon, Apr 27
Allegiant Air Logo
1:22 pm - 1:58 pm
TYS
-
MDW
1h 36mnonstop
Allegiant Air Logo
9:15 pm - 9:42 pm
MDW
-
TYS
23h 27m
1 stop
$245Allegiant Air
Sun, Jul 12 - Fri, Jul 24
Southwest Logo
12:50 pm - 5:30 pm
TYS
-
MDW
5h 40m
1 stop
Southwest Logo
9:25 am - 5:10 pm
MDW
-
TYS
6h 45m
1 stop
$249Southwest
Tue, Apr 14 - Tue, Apr 21
Multiple Airlines Logo
1:22 pm - 1:57 pm
TYS
-
MDW
1h 35mnonstop
Multiple Airlines Logo
12:04 pm - 11:37 pm
MDW
-
TYS
10h 33m
2 stops
$252Multiple Airlines
Thu, May 28 - Mon, Jun 1
Southwest Logo
5:50 pm - 10:15 pm
TYS
-
MDW
5h 25m
1 stop
Southwest Logo
10:15 am - 8:50 pm
MDW
-
TYS
9h 35m
2 stops
$254Southwest
Tue, Apr 14 - Tue, Apr 21
Southwest Logo
5:50 pm - 10:15 pm
TYS
-
MDW
5h 25m
1 stop
Southwest Logo
7:25 am - 3:20 pm
MDW
-
TYS
6h 55m
1 stop
$259Southwest
Tue, May 5 - Sat, May 9

Delta flights from Knoxville to Chicago Midway Airport

Our best Delta deals on Knoxville to Chicago Midway Airport flight tickets
Delta
May 9
TYS4:00 pmKnoxville McGhee Tyson
6h 09m
1 stop
MDW9:09 pmChicago Midway
May 11
MDW6:23 amChicago Midway
5h 47m
1 stop
TYS1:10 pmKnoxville McGhee Tyson
$269
Delta
Apr 14
TYS7:50 amKnoxville McGhee Tyson
5h 53m
1 stop
MDW12:43 pmChicago Midway
Apr 15
MDW9:27 amChicago Midway
6h 15m
1 stop
TYS4:42 pmKnoxville McGhee Tyson
$271
Delta
Apr 1
TYS7:40 amKnoxville McGhee Tyson
5h 49m
1 stop
MDW12:29 pmChicago Midway
Apr 11
MDW10:45 amChicago Midway
4h 28m
1 stop
TYS4:13 pmKnoxville McGhee Tyson
$284

Allegiant Air flights from Knoxville to Chicago Midway Airport

Our best Allegiant Air deals on Knoxville to Chicago Midway Airport flight tickets
Allegiant Air
Jul 16
TYS1:22 pmKnoxville McGhee Tyson
1h 36m
MDW1:58 pmChicago Midway
Jul 19
MDW2:48 pmChicago Midway
1h 30m
TYS5:18 pmKnoxville McGhee Tyson
$220
Allegiant Air
Jul 16
TYS1:22 pmKnoxville McGhee Tyson
1h 36m
MDW1:58 pmChicago Midway
Jul 23
MDW2:48 pmChicago Midway
1h 30m
TYS5:18 pmKnoxville McGhee Tyson
$231
Allegiant Air
Jul 23
TYS1:22 pmKnoxville McGhee Tyson
1h 36m
MDW1:58 pmChicago Midway
Jul 26
MDW2:48 pmChicago Midway
1h 30m
TYS5:18 pmKnoxville McGhee Tyson
$233

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Chicago Midway Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 22, 2026.
Use the filters below to find and compare flights from Knoxville to Chicago Midway Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Thu 7/16

1:22 pm-1:58 pm

Nonstop1h 36m

Chicago Midway

Sun 7/19

2:48 pm-5:18 pm

Nonstop1h 30m

$220

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Thu 7/16

1:22 pm-1:58 pm

Nonstop1h 36m

Chicago Midway

Thu 7/23

2:48 pm-5:18 pm

Nonstop1h 30m

$231

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Thu 7/23

1:22 pm-1:58 pm

Nonstop1h 36m

Chicago Midway

Sun 7/26

2:48 pm-5:18 pm

Nonstop1h 30m

$233

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Sat 6/6

9:00 am-8:21 am

1 stop24h 21m

Chicago Midway

Thu 6/11

2:46 pm-5:14 pm

Nonstop1h 28m

$242

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Mon 4/20

1:15 pm-10:14 pm

2 stops33h 59m

Chicago Midway

Mon 4/27

9:14 am-5:30 pm

1 stop7h 16m

$243

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Sun 7/12

1:22 pm-1:58 pm

Nonstop1h 36m

Chicago Midway

Fri 7/24

9:15 pm-9:42 pm

1 stop23h 27m

$245

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Tue 4/14

12:50 pm-5:30 pm

1 stop5h 40m

Chicago Midway

Tue 4/21

9:25 am-5:10 pm

1 stop6h 45m

$249

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Thu 5/28

1:22 pm-1:57 pm

Nonstop1h 35m

Chicago Midway

Mon 6/1

12:04 pm-11:37 pm

2 stops10h 33m

$252

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Tue 4/14

5:50 pm-10:15 pm

1 stop5h 25m

Chicago Midway

Tue 4/21

10:15 am-8:50 pm

2 stops9h 35m

$254

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Tue 5/5

5:50 pm-10:15 pm

1 stop5h 25m

Chicago Midway

Sat 5/9

7:25 am-3:20 pm

1 stop6h 55m

$259

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Chicago from

How to get the cheapest flight ticket from Knoxville to Chicago Midway Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Chicago Midway Airport?

According to our data, Sunday is the cheapest day to fly to Chicago Midway Airport from Knoxville. The lowest ticket price found for a Sunday departure recently was $78. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. On the other hand, Wednesday is the most expensive day to depart from Knoxville because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $264.

What is the cheapest time of day to depart on your flight to Chicago Midway Airport?

Flying to Chicago Midway Airport from Knoxville at noon is the least expensive time of day to depart. momondo users have found prices as low as $88 when looking at flights departing at noon. Try not to purchase tickets in the morning because they tend to be around $124. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Knoxville McGhee Tyson to Chicago Midway flight route?

Fly from Knoxville McGhee Tyson to Chicago Midway for the best Knoxville McGhee Tyson - Chicago Midway flight prices

What cabin class options are available on Knoxville McGhee Tyson to Chicago Midway flights?

There is only 1 cabin class available to choose from on Knoxville McGhee Tyson to Chicago Midway flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Knoxville to Chicago Midway Airport flights?

No. A direct flight is the cheapest option for a flight between Knoxville to Chicago Midway Airport.

When to book flights from Knoxville to Chicago Midway Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Chicago Midway Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Chicago Midway Airport (TYS to MDW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Chicago Midway Airport

Best Price Found

$113

Fastest flight time

1h 34m

Direct flights

Mon and Fri
The best flight deal from Knoxville to Chicago Midway Airport found on momondo in the last 72 hours is $113
The fastest flight from Knoxville to Chicago Midway Airport takes 1h 34m
Direct flights go from Knoxville to Chicago Midway Airport on Monday and Friday. There are no airlines offering direct flights.
Search flight deals

  • How far is Knoxville McGhee Tyson to Chicago Midway by plane?

    Knoxville McGhee Tyson and Chicago Midway are 451.6 mi apart from one another. A reasonable flight in good conditions will take 1h 34m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Chicago Midway Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Chicago Midway Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Chicago Midway Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Chicago Midway Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Chicago Midway Airport.

  • What documentation or ID do you need to fly to Chicago Midway Airport?

    The travel and health documents you'll need for your trip to Chicago Midway Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Chicago Midway Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Knoxville to Chicago Midway Airport?

  • What is the most popular airline from Knoxville to Chicago Midway Airport?

Best airlines flying from Knoxville to Chicago Midway Airport

Compare and see reviews for airlines that fly from Knoxville to Chicago Midway Airport with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $60Free CancellationRating
7.3
711 reviews
Search Allegiant Air flights

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
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Hammond
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Benton Harbor
Portage
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Schererville
Munster
Crown Point
Chesterton
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Porter
Griffith
Saint John

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Chicago?

It is quick and easy to find Knoxville to Chicago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Chicago that suits you.

Can I find flights from Knoxville to Chicago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Chicago from Knoxville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Knoxville to Chicago?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Knoxville to Chicago.

I’m not ready to book a flight from Knoxville to Chicago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Knoxville to Chicago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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