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Cheap flights from Knoxville to Chicago from $62

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Chicago departing on 10/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Chicago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
1:49 pm - 2:26 pmTYS  Knoxville McGhee Tyson-MDW Chicago Midway
1h 37mnonstop
Allegiant Air Logo
10:42 am - 5:02 pmMDW  Chicago Midway-TYS Knoxville McGhee Tyson
29h 20m1 stop Punta Gorda
$196Allegiant Air
Fri, Nov 13 - Sun, Nov 15
Allegiant Air Logo
6:23 pm - 8:25 pmTYS  Knoxville McGhee Tyson-MDW Chicago Midway
27h 02m1 stop Valparaiso Destin-Ft Walton Beach
Allegiant Air Logo
1:26 pm - 3:51 pmMDW  Chicago Midway-TYS Knoxville McGhee Tyson
1h 25mnonstop
$216Allegiant Air
Thu, Oct 22 - Mon, Oct 26
Allegiant Air Logo
10:55 am - 9:18 amTYS  Knoxville McGhee Tyson-MDW Chicago Midway
23h 23m1 stop Punta Gorda
Allegiant Air Logo
2:26 pm - 4:51 pmMDW  Chicago Midway-TYS Knoxville McGhee Tyson
1h 25mnonstop
$232Allegiant Air
Wed, Oct 21 - Fri, Oct 23
Allegiant Air Logo
6:42 pm - 7:19 pmTYS  Knoxville McGhee Tyson-MDW Chicago Midway
1h 37mnonstop
Allegiant Air Logo
10:42 am - 4:32 pmMDW  Chicago Midway-TYS Knoxville McGhee Tyson
28h 50m1 stop Punta Gorda
$237Allegiant Air
Fri, Nov 6 - Sun, Nov 8
Multiple Airlines Logo
2:01 pm - 10:58 amTYS  Knoxville McGhee Tyson-MDW Chicago Midway
21h 57m2 stops Jacksonville Atlanta Hartsfield-Jackson
Multiple Airlines Logo
1:26 pm - 3:51 pmMDW  Chicago Midway-TYS Knoxville McGhee Tyson
1h 25mnonstop
$242Multiple Airlines
Thu, Oct 22 - Mon, Oct 26
Multiple Airlines Logo
2:01 pm - 10:58 amTYS  Knoxville McGhee Tyson-MDW Chicago Midway
21h 57m2 stops Jacksonville Atlanta Hartsfield-Jackson
Multiple Airlines Logo
1:26 pm - 3:51 pmMDW  Chicago Midway-TYS Knoxville McGhee Tyson
1h 25mnonstop
$245Multiple Airlines
Thu, Oct 22 - Mon, Oct 26
Allegiant Air Logo
12:04 pm - 12:36 pmTYS  Knoxville McGhee Tyson-MDW Chicago Midway
1h 32mnonstop
Allegiant Air Logo
10:42 am - 4:32 pmMDW  Chicago Midway-TYS Knoxville McGhee Tyson
28h 50m1 stop Punta Gorda
$250Allegiant Air
Mon, Nov 2 - Sun, Nov 8
Multiple Airlines Logo
1:49 pm - 2:26 pmTYS  Knoxville McGhee Tyson-MDW Chicago Midway
1h 37mnonstop
Multiple Airlines Logo
12:03 pm - 10:05 pmMDW  Chicago Midway-TYS Knoxville McGhee Tyson
9h 02m2 stops Atlanta Hartsfield-Jackson Jacksonville
$252Multiple Airlines
Fri, Nov 13 - Sun, Nov 15
Southwest Logo
8:05 am - 11:35 amTYS  Knoxville McGhee Tyson-MDW Chicago Midway
4h 30m1 stop Baltimore/Washington
Southwest Logo
7:25 am - 1:25 pmMDW  Chicago Midway-TYS Knoxville McGhee Tyson
5h 00m1 stop Dallas Love Field
$253Southwest
Tue, Sep 8 - Fri, Sep 11
Southwest Logo
4:55 pm - 7:20 pmTYS  Knoxville McGhee Tyson-MDW Chicago Midway
3h 25m1 stop Nashville Intl
Southwest Logo
6:45 am - 1:15 pmMDW  Chicago Midway-TYS Knoxville McGhee Tyson
5h 30m1 stop Dallas Love Field
$253Southwest
Sat, Aug 29 - Sat, Sep 5

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Allegiant Air flights from Knoxville to Chicago Midway Airport

Our best Allegiant Air deals on Knoxville to Chicago Midway Airport flight tickets
Allegiant Air
Nov 13
TYS1:49 pmKnoxville McGhee Tyson
1h 37m
MDW2:26 pmChicago Midway
Nov 15
MDW10:42 amChicago Midway
29h 20m
1 stop
TYS5:02 pmKnoxville McGhee Tyson
$196
Allegiant Air
Aug 9
TYS1:23 pmKnoxville McGhee Tyson
1h 36m
MDW1:59 pmChicago Midway
Aug 13
MDW2:49 pmChicago Midway
1h 30m
TYS5:19 pmKnoxville McGhee Tyson
$206
Allegiant Air
Oct 22
TYS6:23 pmKnoxville McGhee Tyson
27h 02m
1 stop
MDW8:25 pmChicago Midway
Oct 26
MDW1:26 pmChicago Midway
1h 25m
TYS3:51 pmKnoxville McGhee Tyson
$216

Delta flights from Knoxville to Chicago Midway Airport

Our best Delta deals on Knoxville to Chicago Midway Airport flight tickets
Delta
Aug 28
TYS7:41 pmKnoxville McGhee Tyson
3h 55m
1 stop
MDW10:36 pmChicago Midway
Aug 29
MDW1:25 pmChicago Midway
5h 01m
1 stop
TYS7:26 pmKnoxville McGhee Tyson
$279
Delta
Aug 21
TYS4:38 pmKnoxville McGhee Tyson
6h 58m
1 stop
MDW10:36 pmChicago Midway
Aug 28
MDW5:10 pmChicago Midway
5h 42m
1 stop
TYS11:52 pmKnoxville McGhee Tyson
$294
Delta
Oct 1
TYS7:33 amKnoxville McGhee Tyson
6h 06m
1 stop
MDW12:39 pmChicago Midway
Oct 4
MDW6:05 amChicago Midway
4h 13m
1 stop
TYS11:18 amKnoxville McGhee Tyson
$319

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Chicago Midway Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 5, 2026.
Use the filters below to find and compare flights from Knoxville to Chicago Midway Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleChicago

TYS Knoxville McGhee Tyson - MDW Chicago Midway

TYSMDW

Knoxville McGhee Tyson

Fri 11/13

1:49 pm-2:26 pm

Nonstop1h 37m

Chicago Midway

Sun 11/15

10:42 am-5:02 pm

1 stop29h 20m

$196

KnoxvilleChicago

TYS Knoxville McGhee Tyson - MDW Chicago Midway

TYSMDW

Knoxville McGhee Tyson

Thu 10/22

6:23 pm-8:25 pm

1 stop27h 02m

Chicago Midway

Mon 10/26

1:26 pm-3:51 pm

Nonstop1h 25m

$216

KnoxvilleChicago

TYS Knoxville McGhee Tyson - MDW Chicago Midway

TYSMDW

Knoxville McGhee Tyson

Wed 10/21

10:55 am-9:18 am

1 stop23h 23m

Chicago Midway

Fri 10/23

2:26 pm-4:51 pm

Nonstop1h 25m

$232

KnoxvilleChicago

TYS Knoxville McGhee Tyson - MDW Chicago Midway

TYSMDW

Knoxville McGhee Tyson

Fri 11/6

6:42 pm-7:19 pm

Nonstop1h 37m

Chicago Midway

Sun 11/8

10:42 am-4:32 pm

1 stop28h 50m

$237

KnoxvilleChicago

TYS Knoxville McGhee Tyson - MDW Chicago Midway

TYSMDW

Knoxville McGhee Tyson

Thu 10/22

2:01 pm-10:58 am

2 stops21h 57m

Chicago Midway

Mon 10/26

1:26 pm-3:51 pm

Nonstop1h 25m

$242

KnoxvilleChicago

TYS Knoxville McGhee Tyson - MDW Chicago Midway

TYSMDW

Knoxville McGhee Tyson

Thu 10/22

2:01 pm-10:58 am

2 stops21h 57m

Chicago Midway

Mon 10/26

1:26 pm-3:51 pm

Nonstop1h 25m

$245

KnoxvilleChicago

TYS Knoxville McGhee Tyson - MDW Chicago Midway

TYSMDW

Knoxville McGhee Tyson

Mon 11/2

12:04 pm-12:36 pm

Nonstop1h 32m

Chicago Midway

Sun 11/8

10:42 am-4:32 pm

1 stop28h 50m

$250

KnoxvilleChicago

TYS Knoxville McGhee Tyson - MDW Chicago Midway

TYSMDW

Knoxville McGhee Tyson

Fri 11/13

1:49 pm-2:26 pm

Nonstop1h 37m

Chicago Midway

Sun 11/15

12:03 pm-10:05 pm

2 stops9h 02m

$252

KnoxvilleChicago

TYS Knoxville McGhee Tyson - MDW Chicago Midway

TYSMDW

Knoxville McGhee Tyson

Tue 9/8

8:05 am-11:35 am

1 stop4h 30m

Chicago Midway

Fri 9/11

7:25 am-1:25 pm

1 stop5h 00m

$253
Quickest round-trip

KnoxvilleChicago

TYS Knoxville McGhee Tyson - MDW Chicago Midway

TYSMDW

Knoxville McGhee Tyson

Sat 8/29

4:55 pm-7:20 pm

1 stop3h 25m

Chicago Midway

Sat 9/5

6:45 am-1:15 pm

1 stop5h 30m

$253

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Knoxville to Chicago Midway Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Chicago Midway Airport?

The month of March is, on average, the cheapest month to fly to Chicago Midway Airport from Knoxville, with most prices found around $0. If you are unable to visit Chicago Midway Airport during the month of March, then departing from Knoxville during the month February is also very affordable. Most momondo users find prices during this month for around $0.

What is the cheapest day to depart on your flight to Chicago Midway Airport?

According to our data, Saturday is the cheapest day to fly to Chicago Midway Airport from Knoxville. The lowest ticket price found for a Saturday departure recently was $89. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. On the other hand, Wednesday is the most expensive day to depart from Knoxville because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $151.

What is the cheapest time of day to depart on your flight to Chicago Midway Airport?

Flying to Chicago Midway Airport from Knoxville in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $89 when looking at flights departing in the afternoon. Try not to purchase tickets at noon because they tend to be around $129. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Knoxville McGhee Tyson to Chicago Midway flight route?

Fly from Knoxville McGhee Tyson to Chicago Midway for the best Knoxville McGhee Tyson - Chicago Midway flight prices

What cabin class options are available on Knoxville to Chicago Midway Airport flights?

There is only 1 cabin class available to choose from on Knoxville to Chicago Midway Airport flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Knoxville to Chicago Midway Airport flights?

No. A direct flight is the cheapest option for a flight between Knoxville to Chicago Midway Airport.

When to book flights from Knoxville to Chicago Midway Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Chicago Midway Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Chicago Midway Airport (TYS to MDW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Chicago Midway Airport

Best Price Found

$115

Fastest flight time

1h 32m

Direct flights

Mon, Tue, Thu, Fri and Sat
The best one-way flight to Chicago Midway Airport from Knoxville in the past 72 hours is $115. The best round-trip flight deal from Knoxville to Chicago Midway Airport found on momondo in the last 72 hours is $98.
The fastest flight from Knoxville to Chicago Midway Airport takes 1h 32m
Direct flights go from Knoxville to Chicago Midway Airport on Monday, Tuesday, Thursday, Friday and Saturday. The only airline offering direct flights is Allegiant Air.
Search flight deals

Frequently asked questions about flying from Knoxville to Chicago Midway Airport

  • How far is Knoxville McGhee Tyson to Chicago Midway by plane?

    Knoxville McGhee Tyson and Chicago Midway are 451.6 mi apart from one another. A reasonable flight in good conditions will take 1h 32m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Chicago Midway Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Chicago Midway Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Chicago Midway Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Chicago Midway Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Chicago Midway Airport.

  • What documentation or ID do you need to fly to Chicago Midway Airport?

    The travel and health documents you'll need for your trip to Chicago Midway Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Chicago Midway Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Knoxville to Chicago Midway Airport?

  • What is the most popular airline from Knoxville to Chicago Midway Airport?

Best airlines flying from Knoxville to Chicago Midway Airport

Compare and see reviews for airlines that fly from Knoxville to Chicago Midway Airport with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $78Free CancellationRating
7.3
680 reviews
Search Allegiant Air flights

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
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Saint John

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Chicago?

It is quick and easy to find Knoxville to Chicago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Chicago that suits you.

Can I find flights from Knoxville to Chicago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Chicago from Knoxville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Knoxville to Chicago?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Knoxville to Chicago.

I’m not ready to book a flight from Knoxville to Chicago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Knoxville to Chicago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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