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Cheap flights from Knoxville to Chicago from $94

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Chicago departing on 8/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Chicago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
1:23 pm - 1:59 pm
TYS
-
MDW
1h 36mnonstop
Allegiant Air Logo
2:49 pm - 5:19 pm
MDW
-
TYS
1h 30mnonstop
$198Allegiant Air
Sun, Aug 9 - Thu, Aug 13
Allegiant Air Logo
1:49 pm - 2:26 pm
TYS
-
MDW
1h 37mnonstop
Allegiant Air Logo
10:42 am - 4:32 pm
MDW
-
TYS
28h 50m
1 stop
$201Allegiant Air
Fri, Nov 13 - Sun, Nov 15
Multiple Airlines Logo
3:54 pm - 12:07 pm
TYS
-
MDW
21h 13m
2 stops
Multiple Airlines Logo
1:26 pm - 3:51 pm
MDW
-
TYS
1h 25mnonstop
$222Multiple Airlines
Fri, Oct 16 - Mon, Oct 19
Multiple Airlines Logo
3:54 pm - 12:07 pm
TYS
-
MDW
21h 13m
2 stops
Multiple Airlines Logo
1:26 pm - 3:51 pm
MDW
-
TYS
1h 25mnonstop
$223Multiple Airlines
Fri, Oct 16 - Mon, Oct 19
Allegiant Air Logo
3:56 pm - 2:59 pm
TYS
-
MDW
24h 03m
2 stops
Allegiant Air Logo
2:49 pm - 5:19 pm
MDW
-
TYS
1h 30mnonstop
$232Allegiant Air
Thu, Aug 13 - Sun, Aug 16
Allegiant Air Logo
9:26 am - 8:35 pm
TYS
-
MDW
12h 09m
1 stop
Allegiant Air Logo
1:26 pm - 3:51 pm
MDW
-
TYS
1h 25mnonstop
$235Allegiant Air
Fri, Oct 9 - Mon, Oct 12
Southwest Logo
4:55 pm - 7:20 pm
TYS
-
MDW
3h 25m
1 stop
Southwest Logo
9:10 am - 5:10 pm
MDW
-
TYS
7h 00m
1 stop
$237Southwest
Sat, Aug 22 - Mon, Aug 24
Multiple Airlines Logo
1:49 pm - 2:26 pm
TYS
-
MDW
1h 37mnonstop
Multiple Airlines Logo
12:03 pm - 10:05 pm
MDW
-
TYS
9h 02m
2 stops
$241Multiple Airlines
Fri, Nov 13 - Sun, Nov 15
Southwest Logo
4:55 pm - 7:20 pm
TYS
-
MDW
3h 25m
1 stop
Southwest Logo
9:10 am - 6:35 pm
MDW
-
TYS
8h 25m
2 stops
$242Southwest
Sat, Aug 22 - Mon, Aug 24
Southwest Logo
5:30 pm - 10:25 pm
TYS
-
MDW
5h 55m
1 stop
Southwest Logo
5:55 am - 12:20 pm
MDW
-
TYS
5h 25m
1 stop
$243Southwest
Tue, Sep 8 - Thu, Sep 10

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Allegiant Air flights from Knoxville to Chicago Midway Airport

Our best Allegiant Air deals on Knoxville to Chicago Midway Airport flight tickets
Allegiant Air
Aug 9
TYS1:23 pmKnoxville McGhee Tyson
1h 36m
MDW1:59 pmChicago Midway
Aug 13
MDW2:49 pmChicago Midway
1h 30m
TYS5:19 pmKnoxville McGhee Tyson
$198
Allegiant Air
Nov 13
TYS1:49 pmKnoxville McGhee Tyson
1h 37m
MDW2:26 pmChicago Midway
Nov 15
MDW10:42 amChicago Midway
28h 50m
1 stop
TYS4:32 pmKnoxville McGhee Tyson
$201
Allegiant Air
Aug 13
TYS3:56 pmKnoxville McGhee Tyson
24h 03m
2 stops
MDW2:59 pmChicago Midway
Aug 16
MDW2:49 pmChicago Midway
1h 30m
TYS5:19 pmKnoxville McGhee Tyson
$232

Southwest flights from Knoxville to Chicago Midway Airport

Our best Southwest deals on Knoxville to Chicago Midway Airport flight tickets
Southwest
Aug 22
TYS4:55 pmKnoxville McGhee Tyson
3h 25m
1 stop
MDW7:20 pmChicago Midway
Aug 24
MDW9:10 amChicago Midway
7h 00m
1 stop
TYS5:10 pmKnoxville McGhee Tyson
$237
Southwest
Aug 22
TYS4:55 pmKnoxville McGhee Tyson
3h 25m
1 stop
MDW7:20 pmChicago Midway
Aug 24
MDW9:10 amChicago Midway
8h 25m
2 stops
TYS6:35 pmKnoxville McGhee Tyson
$242
Southwest
Sep 8
TYS5:30 pmKnoxville McGhee Tyson
5h 55m
1 stop
MDW10:25 pmChicago Midway
Sep 10
MDW5:55 amChicago Midway
5h 25m
1 stop
TYS12:20 pmKnoxville McGhee Tyson
$243

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Chicago Midway Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 26, 2026.
Use the filters below to find and compare flights from Knoxville to Chicago Midway Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Sun 8/9

1:23 pm-1:59 pm

Nonstop1h 36m

Chicago Midway

Thu 8/13

2:49 pm-5:19 pm

Nonstop1h 30m

$198

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Fri 11/13

1:49 pm-2:26 pm

Nonstop1h 37m

Chicago Midway

Sun 11/15

10:42 am-4:32 pm

1 stop28h 50m

$201

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Fri 10/16

3:54 pm-12:07 pm

2 stops21h 13m

Chicago Midway

Mon 10/19

1:26 pm-3:51 pm

Nonstop1h 25m

$222

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Fri 10/16

3:54 pm-12:07 pm

2 stops21h 13m

Chicago Midway

Mon 10/19

1:26 pm-3:51 pm

Nonstop1h 25m

$223

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Thu 8/13

3:56 pm-2:59 pm

2 stops24h 03m

Chicago Midway

Sun 8/16

2:49 pm-5:19 pm

Nonstop1h 30m

$232

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Fri 10/9

9:26 am-8:35 pm

1 stop12h 09m

Chicago Midway

Mon 10/12

1:26 pm-3:51 pm

Nonstop1h 25m

$235

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Sat 8/22

4:55 pm-7:20 pm

1 stop3h 25m

Chicago Midway

Mon 8/24

9:10 am-5:10 pm

1 stop7h 00m

$237

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Fri 11/13

1:49 pm-2:26 pm

Nonstop1h 37m

Chicago Midway

Sun 11/15

12:03 pm-10:05 pm

2 stops9h 02m

$241

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Sat 8/22

4:55 pm-7:20 pm

1 stop3h 25m

Chicago Midway

Mon 8/24

9:10 am-6:35 pm

2 stops8h 25m

$242

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Tue 9/8

5:30 pm-10:25 pm

1 stop5h 55m

Chicago Midway

Thu 9/10

5:55 am-12:20 pm

1 stop5h 25m

$243

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Chicago from

How to get the cheapest flight ticket from Knoxville to Chicago Midway Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Chicago Midway Airport?

The month of March is, on average, the cheapest month to fly to Chicago Midway Airport from Knoxville, with most prices found around $0. If you are unable to visit Chicago Midway Airport during the month of March, then departing from Knoxville during the month February is also very affordable. Most momondo users find prices during this month for around $0.

What is the cheapest day to depart on your flight to Chicago Midway Airport?

According to our data, Saturday is the cheapest day to fly to Chicago Midway Airport from Knoxville. The lowest ticket price found for a Saturday departure recently was $89. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. On the other hand, Wednesday is the most expensive day to depart from Knoxville because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $151.

What is the cheapest time of day to depart on your flight to Chicago Midway Airport?

Flying to Chicago Midway Airport from Knoxville in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $89 when looking at flights departing in the afternoon. Try not to purchase tickets at noon because they tend to be around $129. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Knoxville McGhee Tyson to Chicago Midway flight route?

Fly from Knoxville McGhee Tyson to Chicago Midway for the best Knoxville McGhee Tyson - Chicago Midway flight prices

What cabin class options are available on Knoxville to Chicago Midway Airport flights?

There is only 1 cabin class available to choose from on Knoxville to Chicago Midway Airport flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Knoxville to Chicago Midway Airport flights?

No. A direct flight is the cheapest option for a flight between Knoxville to Chicago Midway Airport.

When to book flights from Knoxville to Chicago Midway Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Chicago Midway Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Chicago Midway Airport (TYS to MDW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Chicago Midway Airport

Best Price Found

$84

Fastest flight time

1h 32m

Direct flights

Mon, Thu, Fri and Sat
The best one-way flight to Chicago Midway Airport from Knoxville in the past 72 hours is $84. The best round-trip flight deal from Knoxville to Chicago Midway Airport found on momondo in the last 72 hours is $112.
The fastest flight from Knoxville to Chicago Midway Airport takes 1h 32m
Direct flights go from Knoxville to Chicago Midway Airport on Monday, Thursday, Friday and Saturday. The only airline offering direct flights is Allegiant Air.
Search flight deals

Frequently asked questions about flying from Knoxville to Chicago Midway Airport

  • How far is Knoxville McGhee Tyson to Chicago Midway by plane?

    Knoxville McGhee Tyson and Chicago Midway are 451.6 mi apart from one another. A reasonable flight in good conditions will take 1h 32m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Chicago Midway Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Chicago Midway Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Chicago Midway Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Chicago Midway Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Chicago Midway Airport.

  • What documentation or ID do you need to fly to Chicago Midway Airport?

    The travel and health documents you'll need for your trip to Chicago Midway Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Chicago Midway Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Knoxville to Chicago Midway Airport?

  • What is the most popular airline from Knoxville to Chicago Midway Airport?

Best airlines flying from Knoxville to Chicago Midway Airport

Compare and see reviews for airlines that fly from Knoxville to Chicago Midway Airport with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $73Free CancellationRating
7.3
681 reviews
Search Allegiant Air flights

  • Allegiant Air Flights From Knoxville to Chicago Midway Airport

    Allegiant Air is one of the most popular airlines flying from Knoxville to Chicago Midway Airport, operating 1 flight/week on average for this route. A good Allegiant Air flight deal for Knoxville to Chicago Midway Airport starts from $73 round-trip, up to an average price of $129. Our users have rated Allegiant Air at 7.3/10.

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
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Hammond
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Benton Harbor
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Saint Joseph
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Schererville
Munster
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Saint John

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Chicago?

It is quick and easy to find Knoxville to Chicago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Chicago that suits you.

Can I find flights from Knoxville to Chicago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Chicago from Knoxville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Knoxville to Chicago?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Knoxville to Chicago.

I’m not ready to book a flight from Knoxville to Chicago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Knoxville to Chicago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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