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Cheap flights from Knoxville to Sao Paulo from $1,053

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Sao Paulo departing on 8/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Knoxville to Sao Paulo

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
1:00 pm - 9:30 am
TYS
-
GRU
19h 30m
1 stop
United Airlines Logo
9:30 pm - 10:37 am
GRU
-
TYS
14h 07m
1 stop
$1,053United Airlines
Wed, Aug 19 - Wed, Aug 26
American Airlines Logo
11:49 am - 5:55 am
TYS
-
GRU
17h 06m
2 stops
American Airlines Logo
11:15 pm - 1:31 pm
GRU
-
TYS
15h 16m
2 stops
$1,057American Airlines
Wed, Aug 19 - Wed, Aug 26
United Airlines Logo
9:45 am - 10:20 am
TYS
-
GRU
22h 35m
1 stop
United Airlines Logo
10:15 pm - 5:37 pm
GRU
-
TYS
21h 22m
1 stop
$1,083United Airlines
Fri, Nov 27 - Tue, Dec 1
United Airlines Logo
10:48 am - 9:30 am
TYS
-
GRU
20h 42m
2 stops
United Airlines Logo
9:45 pm - 1:18 pm
GRU
-
TYS
17h 33m
2 stops
$1,087United Airlines
Fri, Nov 27 - Tue, Dec 1
LATAM Airlines Logo
12:00 pm - 6:50 am
TYS
-
GRU
16h 50m
2 stops
LATAM Airlines Logo
8:00 am - 11:46 pm
GRU
-
TYS
17h 46m
2 stops
$1,093LATAM Airlines
Fri, Nov 27 - Tue, Dec 1
American Airlines Logo
5:35 pm - 9:00 am
TYS
-
GRU
14h 25m
1 stop
American Airlines Logo
11:15 pm - 6:04 pm
GRU
-
TYS
19h 49m
1 stop
$1,113American Airlines
Fri, Oct 2 - Sat, Apr 10
American Airlines Logo
2:43 pm - 9:00 am
TYS
-
GRU
17h 17m
1 stop
American Airlines Logo
9:25 pm - 2:24 pm
GRU
-
TYS
17h 59m
2 stops
$1,117American Airlines
Fri, Oct 2 - Sat, Apr 10
LATAM Airlines Logo
12:23 pm - 5:30 am
TYS
-
GRU
16h 07m
2 stops
LATAM Airlines Logo
8:15 am - 9:12 am
GRU
-
TYS
25h 57m
2 stops
$1,123LATAM Airlines
Fri, Oct 2 - Sat, Apr 10
United Airlines Logo
7:15 am - 6:30 am
TYS
-
GRU
22h 15m
1 stop
United Airlines Logo
9:30 pm - 2:27 pm
GRU
-
TYS
17h 57m
1 stop
$1,153United Airlines
Tue, Jul 28 - Tue, Aug 4
United Airlines Logo
6:00 am - 6:30 am
TYS
-
GRU
23h 30m
2 stops
United Airlines Logo
10:20 pm - 2:27 pm
GRU
-
TYS
17h 07m
2 stops
$1,157United Airlines
Tue, Jul 28 - Tue, Aug 4

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American Airlines flights from Knoxville to Sao Paulo

Our best American Airlines deals on Knoxville to Sao Paulo flight tickets
American Airlines
Aug 19
TYS11:49 amKnoxville McGhee Tyson
17h 06m
2 stops
GRU5:55 amSao Paulo Guarulhos Intl
Aug 26
GRU11:15 pmSao Paulo Guarulhos Intl
15h 16m
2 stops
TYS1:31 pmKnoxville McGhee Tyson
$1,057
American Airlines
Oct 2
TYS5:35 pmKnoxville McGhee Tyson
14h 25m
1 stop
GRU9:00 amSao Paulo Guarulhos Intl
Apr 10
GRU11:15 pmSao Paulo Guarulhos Intl
19h 49m
1 stop
TYS6:04 pmKnoxville McGhee Tyson
$1,113
American Airlines
Oct 2
TYS2:43 pmKnoxville McGhee Tyson
17h 17m
1 stop
GRU9:00 amSao Paulo Guarulhos Intl
Apr 10
GRU9:25 pmSao Paulo Guarulhos Intl
17h 59m
2 stops
TYS2:24 pmKnoxville McGhee Tyson
$1,117

LATAM Airlines flights from Knoxville to Sao Paulo

Our best LATAM Airlines deals on Knoxville to Sao Paulo flight tickets
LATAM Airlines
Nov 27
TYS12:00 pmKnoxville McGhee Tyson
16h 50m
2 stops
GRU6:50 amSao Paulo Guarulhos Intl
Dec 1
GRU8:00 amSao Paulo Guarulhos Intl
17h 46m
2 stops
TYS11:46 pmKnoxville McGhee Tyson
$1,093
LATAM Airlines
Oct 2
TYS12:23 pmKnoxville McGhee Tyson
16h 07m
2 stops
GRU5:30 amSao Paulo Guarulhos Intl
Apr 10
GRU8:15 amSao Paulo Guarulhos Intl
25h 57m
2 stops
TYS9:12 amKnoxville McGhee Tyson
$1,123
LATAM Airlines
Jul 18
TYS5:37 pmKnoxville McGhee Tyson
36h 38m
2 stops
GRU7:15 amSao Paulo Guarulhos Intl
Jul 28
GRU11:40 amSao Paulo Guarulhos Intl
23h 08m
2 stops
TYS9:48 amKnoxville McGhee Tyson
$1,292

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Sao Paulo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 5, 2026.
Use the filters below to find and compare flights from Knoxville to Sao Paulo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Wed 8/19

1:00 pm-9:30 am

1 stop19h 30m

Sao Paulo Guarulhos Intl

Wed 8/26

9:30 pm-10:37 am

1 stop14h 07m

$1,053
Quickest round-trip

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Wed 8/19

11:49 am-5:55 am

2 stops17h 06m

Sao Paulo Guarulhos Intl

Wed 8/26

11:15 pm-1:31 pm

2 stops15h 16m

$1,057

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Fri 11/27

9:45 am-10:20 am

1 stop22h 35m

Sao Paulo Guarulhos Intl

Tue 12/1

10:15 pm-5:37 pm

1 stop21h 22m

$1,083

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Fri 11/27

10:48 am-9:30 am

2 stops20h 42m

Sao Paulo Guarulhos Intl

Tue 12/1

9:45 pm-1:18 pm

2 stops17h 33m

$1,087

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Fri 11/27

12:00 pm-6:50 am

2 stops16h 50m

Sao Paulo Guarulhos Intl

Tue 12/1

8:00 am-11:46 pm

2 stops17h 46m

$1,093

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Fri 10/2

5:35 pm-9:00 am

1 stop14h 25m

Sao Paulo Guarulhos Intl

Sat 4/10

11:15 pm-6:04 pm

1 stop19h 49m

$1,113

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Fri 10/2

2:43 pm-9:00 am

1 stop17h 17m

Sao Paulo Guarulhos Intl

Sat 4/10

9:25 pm-2:24 pm

2 stops17h 59m

$1,117

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Fri 10/2

12:23 pm-5:30 am

2 stops16h 07m

Sao Paulo Guarulhos Intl

Sat 4/10

8:15 am-9:12 am

2 stops25h 57m

$1,123

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Tue 7/28

7:15 am-6:30 am

1 stop22h 15m

Sao Paulo Guarulhos Intl

Tue 8/4

9:30 pm-2:27 pm

1 stop17h 57m

$1,153

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Tue 7/28

6:00 am-6:30 am

2 stops23h 30m

Sao Paulo Guarulhos Intl

Tue 8/4

10:20 pm-2:27 pm

2 stops17h 07m

$1,157

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Sao Paulo from

How to get the cheapest flight ticket from Knoxville to Sao Paulo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Knoxville to Sao Paulo flights?

You could potentially save up to 39% on your flight if you consider stops on a Knoxville to Sao Paulo flight.

When to book flights from Knoxville to Sao Paulo

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Sao Paulo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Sao Paulo (TYS to SAO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Sao Paulo

Fastest flight time

13h 11m

Direct flights

None
The fastest flight from Knoxville to Sao Paulo takes 13h 11m
There are no direct flights from Knoxville to Sao Paulo. There are no popular flight routes from Knoxville to Sao Paulo.
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Frequently asked questions about flying from Knoxville to Sao Paulo

  • How far is Knoxville McGhee Tyson to Sao Paulo by plane?

    There are 4775.1 mi between Knoxville McGhee Tyson and Sao Paulo. Flights usually cover this in 13h 11m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Sao Paulo?

    Prices for flights from Knoxville McGhee Tyson Airport to Sao Paulo are updated daily.

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Sao Paulo?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Sao Paulo.

  • What documentation or ID do you need to fly to Sao Paulo?

    The required travel and health documents for your Sao Paulo trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Sao Paulo. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Sao Paulo?

Book flights to Sao Paulo if you plan to visit one of these locations
Santos
Guarujá

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Sao Paulo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Sao Paulo from Knoxville.

Can I find flights from Knoxville to Sao Paulo with flexible booking policies on momondo?

All flight searches from Knoxville to Sao Paulo on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Knoxville to Sao Paulo?

Once all potential Knoxville to Sao Paulo flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Knoxville to Sao Paulo right now. Can momondo alert me if prices change?

Price alerts on flights to Sao Paulo from Knoxville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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Find better results for your trip to Brazil

Fly into one of these airports located in Sao Paulo

Airports listed have a maximum distance of 48.9 mi from Sao Paulo
Sao Paulo Congonhas Airport
Sao Paulo Guarulhos Intl Airport
Sao Paulo Viracopos Airport