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Cheap flights from Knoxville to Sao Paulo from $518

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Sao Paulo departing on 2/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
LATAM Airlines Logo
7:20 pm - 4:15 pm
TYS
-
GRU
19h 55m
2 stops
LATAM Airlines Logo
11:45 pm - 6:15 pm
GRU
-
TYS
19h 30m
2 stops
$1,054LATAM Airlines
jue., jun. 18 - lun., jun. 29
Delta Logo
5:54 pm - 4:15 pm
TYS
-
GRU
21h 21m
2 stops
Delta Logo
10:50 pm - 3:07 pm
GRU
-
TYS
17h 17m
1 stop
$1,091Delta
vie., may. 1 - mié., ago. 26
United Airlines Logo
5:27 pm - 7:15 am
TYS
-
GRU
35h 48m
1 stop
United Airlines Logo
10:20 pm - 1:17 pm
GRU
-
TYS
15h 57m
1 stop
$1,146United Airlines
dom., mar. 1 - mié., abr. 1
United Airlines Logo
5:27 pm - 7:15 am
TYS
-
GRU
35h 48m
1 stop
United Airlines Logo
9:50 pm - 4:52 pm
GRU
-
TYS
20h 02m
2 stops
$1,151United Airlines
dom., mar. 1 - mié., abr. 1
United Airlines Logo
10:16 am - 9:30 am
TYS
-
GRU
22h 14m
1 stop
United Airlines Logo
10:20 pm - 8:22 pm
GRU
-
TYS
23h 02m
2 stops
$1,162United Airlines
jue., jun. 18 - lun., jun. 29
American Airlines Logo
8:24 am - 6:20 am
TYS
-
GRU
19h 56m
2 stops
American Airlines Logo
11:15 pm - 3:48 pm
GRU
-
TYS
17h 33m
2 stops
$1,182American Airlines
dom., mar. 1 - mié., abr. 1
Delta Logo
4:38 pm - 5:40 am
TYS
-
GRU
12h 02m
1 stop
Delta Logo
10:50 pm - 3:07 pm
GRU
-
TYS
17h 17m
1 stop
$1,186Delta
vie., may. 1 - mié., ago. 26
United Airlines Logo
10:16 am - 9:30 am
TYS
-
GRU
22h 14m
1 stop
United Airlines Logo
9:30 pm - 10:00 am
GRU
-
TYS
13h 30m
1 stop
$1,365United Airlines
jue., jun. 18 - lun., jun. 29

Delta flights from Knoxville to Sao Paulo

Our best Delta deals on Knoxville to Sao Paulo flight tickets
Delta
May 1
TYS5:54 pmKnoxville McGhee Tyson
21h 21m
2 stops
GRU4:15 pmSao Paulo Guarulhos Intl
Aug 26
GRU10:50 pmSao Paulo Guarulhos Intl
17h 17m
1 stop
TYS3:07 pmKnoxville McGhee Tyson
$1,091
Delta
May 1
TYS4:38 pmKnoxville McGhee Tyson
12h 02m
1 stop
GRU5:40 amSao Paulo Guarulhos Intl
Aug 26
GRU10:50 pmSao Paulo Guarulhos Intl
17h 17m
1 stop
TYS3:07 pmKnoxville McGhee Tyson
$1,186

United Airlines flights from Knoxville to Sao Paulo

Our best United Airlines deals on Knoxville to Sao Paulo flight tickets
United Airlines
Mar 1
TYS5:27 pmKnoxville McGhee Tyson
35h 48m
1 stop
GRU7:15 amSao Paulo Guarulhos Intl
Apr 1
GRU10:20 pmSao Paulo Guarulhos Intl
15h 57m
1 stop
TYS1:17 pmKnoxville McGhee Tyson
$1,146
United Airlines
Mar 1
TYS5:27 pmKnoxville McGhee Tyson
35h 48m
1 stop
GRU7:15 amSao Paulo Guarulhos Intl
Apr 1
GRU9:50 pmSao Paulo Guarulhos Intl
20h 02m
2 stops
TYS4:52 pmKnoxville McGhee Tyson
$1,151
United Airlines
Jun 18
TYS10:16 amKnoxville McGhee Tyson
22h 14m
1 stop
GRU9:30 amSao Paulo Guarulhos Intl
Jun 29
GRU10:20 pmSao Paulo Guarulhos Intl
23h 02m
2 stops
TYS8:22 pmKnoxville McGhee Tyson
$1,162

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Sao Paulo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated enero 27, 2026.
Use the filters below to find and compare flights from Knoxville to Sao Paulo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

jue. 6/18

7:20 pm-4:15 pm

2 stops19h 55m

Sao Paulo Guarulhos Intl

lun. 6/29

11:45 pm-6:15 pm

2 stops19h 30m

$1,054

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

vie. 5/1

5:54 pm-4:15 pm

2 stops21h 21m

Sao Paulo Guarulhos Intl

mié. 8/26

10:50 pm-3:07 pm

1 stop17h 17m

$1,091

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

dom. 3/1

5:27 pm-7:15 am

1 stop35h 48m

Sao Paulo Guarulhos Intl

mié. 4/1

10:20 pm-1:17 pm

1 stop15h 57m

$1,146

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

dom. 3/1

5:27 pm-7:15 am

1 stop35h 48m

Sao Paulo Guarulhos Intl

mié. 4/1

9:50 pm-4:52 pm

2 stops20h 02m

$1,151

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

jue. 6/18

10:16 am-9:30 am

1 stop22h 14m

Sao Paulo Guarulhos Intl

lun. 6/29

10:20 pm-8:22 pm

2 stops23h 02m

$1,162

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

dom. 3/1

8:24 am-6:20 am

2 stops19h 56m

Sao Paulo Guarulhos Intl

mié. 4/1

11:15 pm-3:48 pm

2 stops17h 33m

$1,182

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

vie. 5/1

4:38 pm-5:40 am

1 stop12h 02m

Sao Paulo Guarulhos Intl

mié. 8/26

10:50 pm-3:07 pm

1 stop17h 17m

$1,186

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

jue. 6/18

10:16 am-9:30 am

1 stop22h 14m

Sao Paulo Guarulhos Intl

lun. 6/29

9:30 pm-10:00 am

1 stop13h 30m

$1,365

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

jue. 2/5

8:00 am-7:30 am

3 stops45h 30m

$518

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

jue. 2/5

1:39 pm-1:35 am

2 stops33h 56m

$541

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Knoxville to Sao Paulo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Knoxville to Sao Paulo flights?

You could potentially save up to 26% on your flight if you consider stops on a Knoxville to Sao Paulo flight.

When to book flights from Knoxville to Sao Paulo

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Sao Paulo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Sao Paulo (TYS to SAO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Sao Paulo

Fastest flight time

18h 51m

Direct flights

None
The fastest flight from Knoxville to Sao Paulo takes 18h 51m
There are no direct flights from Knoxville to Sao Paulo. There are no popular flight routes from Knoxville to Sao Paulo.
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  • How far is Knoxville McGhee Tyson to Sao Paulo by plane?

    There are 4775.1 mi between Knoxville McGhee Tyson and Sao Paulo. Flights usually cover this in 18h 51m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Sao Paulo?

    Prices for flights from Knoxville McGhee Tyson Airport to Sao Paulo are updated daily.

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Sao Paulo?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Sao Paulo.

  • What documentation or ID do you need to fly to Sao Paulo?

    The required travel and health documents for your Sao Paulo trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Sao Paulo. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Sao Paulo?

Book flights to Sao Paulo if you plan to visit one of these locations
Santos
Guarujá

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Sao Paulo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Sao Paulo from Knoxville.

Can I find flights from Knoxville to Sao Paulo with flexible booking policies on momondo?

All flight searches from Knoxville to Sao Paulo on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Knoxville to Sao Paulo?

Once all potential Knoxville to Sao Paulo flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Knoxville to Sao Paulo right now. Can momondo alert me if prices change?

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jue. 2/26
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Find better results for your trip to Brazil

Fly into one of these airports located in Sao Paulo

Airports listed have a maximum distance of 48.9 mi from Sao Paulo
Sao Paulo Congonhas Airport
Sao Paulo Guarulhos Intl Airport
Sao Paulo Viracopos Airport