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Cheap flights from Knoxville to Sao Paulo from $809

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Sao Paulo departing on 6/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
8:00 am - 12:10 am
TYS
-
GRU
39h 10m
2 stops
Multiple Airlines Logo
11:40 am - 9:13 pm
GRU
-
TYS
34h 33m
1 stop
$809Multiple Airlines
Wed, Jun 3 - Thu, Jun 11
Multiple Airlines Logo
7:15 am - 8:50 pm
TYS
-
GRU
36h 35m
2 stops
Multiple Airlines Logo
11:40 am - 9:13 pm
GRU
-
TYS
34h 33m
1 stop
$901Multiple Airlines
Thu, Jun 4 - Thu, Jun 11
Multiple Airlines Logo
5:00 pm - 12:30 am
TYS
-
GRU
30h 30m
2 stops
Multiple Airlines Logo
11:40 am - 2:52 pm
GRU
-
TYS
28h 12m
1 stop
$927Multiple Airlines
Tue, Jun 2 - Wed, Jun 10
United Airlines Logo
7:15 am - 6:30 am
TYS
-
GRU
22h 15m
1 stop
United Airlines Logo
10:20 pm - 8:48 pm
GRU
-
TYS
23h 28m
1 stop
$1,003United Airlines
Thu, Sep 17 - Tue, Sep 22
United Airlines Logo
5:45 am - 7:10 am
TYS
-
GRU
24h 25m
2 stops
United Airlines Logo
10:20 pm - 1:18 pm
GRU
-
TYS
15h 58m
1 stop
$1,008United Airlines
Wed, Sep 23 - Mon, Sep 28
United Airlines Logo
1:35 pm - 9:30 am
TYS
-
GRU
18h 55m
1 stop
United Airlines Logo
9:50 pm - 6:07 pm
GRU
-
TYS
21h 17m
1 stop
$1,033United Airlines
Wed, Jun 3 - Sun, Jun 7
LATAM Airlines Logo
1:59 pm - 6:10 am
TYS
-
GRU
15h 11m
2 stops
LATAM Airlines Logo
8:15 am - 11:57 pm
GRU
-
TYS
16h 42m
2 stops
$1,045LATAM Airlines
Wed, Jun 3 - Thu, Jun 11
Multiple Airlines Logo
1:22 pm - 10:25 pm
TYS
-
GRU
32h 03m
2 stops
Multiple Airlines Logo
8:50 am - 11:06 pm
GRU
-
TYS
15h 16m
1 stop
$1,047Multiple Airlines
Sun, May 24 - Sun, May 31
GOL Logo
6:00 am - 11:05 pm
TYS
-
GRU
16h 05m
2 stops
GOL Logo
6:00 am - 11:59 pm
GRU
-
TYS
18h 59m
2 stops
$1,051GOL
Mon, Jul 6 - Fri, Jul 10
United Airlines Logo
1:35 pm - 9:30 am
TYS
-
GRU
18h 55m
1 stop
United Airlines Logo
10:20 pm - 1:18 pm
GRU
-
TYS
15h 58m
1 stop
$1,053United Airlines
Wed, Jun 3 - Thu, Jun 11

United Airlines flights from Knoxville to Sao Paulo

Our best United Airlines deals on Knoxville to Sao Paulo flight tickets
United Airlines
Sep 17
TYS7:15 amKnoxville McGhee Tyson
22h 15m
1 stop
GRU6:30 amSao Paulo Guarulhos Intl
Sep 22
GRU10:20 pmSao Paulo Guarulhos Intl
23h 28m
1 stop
TYS8:48 pmKnoxville McGhee Tyson
$1,003
United Airlines
Sep 23
TYS5:45 amKnoxville McGhee Tyson
24h 25m
2 stops
GRU7:10 amSao Paulo Guarulhos Intl
Sep 28
GRU10:20 pmSao Paulo Guarulhos Intl
15h 58m
1 stop
TYS1:18 pmKnoxville McGhee Tyson
$1,008
United Airlines
Jun 3
TYS1:35 pmKnoxville McGhee Tyson
18h 55m
1 stop
GRU9:30 amSao Paulo Guarulhos Intl
Jun 7
GRU9:50 pmSao Paulo Guarulhos Intl
21h 17m
1 stop
TYS6:07 pmKnoxville McGhee Tyson
$1,033

LATAM Airlines flights from Knoxville to Sao Paulo

Our best LATAM Airlines deals on Knoxville to Sao Paulo flight tickets
LATAM Airlines
Jun 3
TYS1:59 pmKnoxville McGhee Tyson
15h 11m
2 stops
GRU6:10 amSao Paulo Guarulhos Intl
Jun 11
GRU8:15 amSao Paulo Guarulhos Intl
16h 42m
2 stops
TYS11:57 pmKnoxville McGhee Tyson
$1,045
LATAM Airlines
Jun 20
TYS5:37 pmKnoxville McGhee Tyson
21h 38m
2 stops
GRU4:15 pmSao Paulo Guarulhos Intl
Jun 27
GRU8:15 amSao Paulo Guarulhos Intl
16h 47m
2 stops
TYS12:02 amKnoxville McGhee Tyson
$1,113
LATAM Airlines
Jul 18
TYS10:26 amKnoxville McGhee Tyson
32h 34m
2 stops
GRU8:00 pmSao Paulo Guarulhos Intl
Jul 27
GRU3:45 amSao Paulo Guarulhos Intl
21h 07m
2 stops
TYS11:52 pmKnoxville McGhee Tyson
$1,119

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Sao Paulo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 6, 2026.
Use the filters below to find and compare flights from Knoxville to Sao Paulo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Wed 6/3

8:00 am-12:10 am

2 stops39h 10m

Sao Paulo Guarulhos Intl

Thu 6/11

11:40 am-9:13 pm

1 stop34h 33m

$809

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Thu 6/4

7:15 am-8:50 pm

2 stops36h 35m

Sao Paulo Guarulhos Intl

Thu 6/11

11:40 am-9:13 pm

1 stop34h 33m

$901

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Tue 6/2

5:00 pm-12:30 am

2 stops30h 30m

Sao Paulo Guarulhos Intl

Wed 6/10

11:40 am-2:52 pm

1 stop28h 12m

$927

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Thu 9/17

7:15 am-6:30 am

1 stop22h 15m

Sao Paulo Guarulhos Intl

Tue 9/22

10:20 pm-8:48 pm

1 stop23h 28m

$1,003

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Wed 9/23

5:45 am-7:10 am

2 stops24h 25m

Sao Paulo Guarulhos Intl

Mon 9/28

10:20 pm-1:18 pm

1 stop15h 58m

$1,008

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Wed 6/3

1:35 pm-9:30 am

1 stop18h 55m

Sao Paulo Guarulhos Intl

Sun 6/7

9:50 pm-6:07 pm

1 stop21h 17m

$1,033
Quickest round-trip

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Wed 6/3

1:59 pm-6:10 am

2 stops15h 11m

Sao Paulo Guarulhos Intl

Thu 6/11

8:15 am-11:57 pm

2 stops16h 42m

$1,045

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Sun 5/24

1:22 pm-10:25 pm

2 stops32h 03m

Sao Paulo Guarulhos Intl

Sun 5/31

8:50 am-11:06 pm

1 stop15h 16m

$1,047

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Mon 7/6

6:00 am-11:05 pm

2 stops16h 05m

Sao Paulo Guarulhos Intl

Fri 7/10

6:00 am-11:59 pm

2 stops18h 59m

$1,051

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Wed 6/3

1:35 pm-9:30 am

1 stop18h 55m

Sao Paulo Guarulhos Intl

Thu 6/11

10:20 pm-1:18 pm

1 stop15h 58m

$1,053

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Sao Paulo from

How to get the cheapest flight ticket from Knoxville to Sao Paulo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Knoxville to Sao Paulo flights?

You could potentially save up to 39% on your flight if you consider stops on a Knoxville to Sao Paulo flight.

When to book flights from Knoxville to Sao Paulo

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Sao Paulo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Sao Paulo (TYS to SAO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Sao Paulo

Fastest flight time

14h 39m

Direct flights

None
The fastest flight from Knoxville to Sao Paulo takes 14h 39m
There are no direct flights from Knoxville to Sao Paulo. There are no popular flight routes from Knoxville to Sao Paulo.
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Frequently asked questions about flying from Knoxville to Sao Paulo

  • How far is Knoxville McGhee Tyson to Sao Paulo by plane?

    There are 4775.1 mi between Knoxville McGhee Tyson and Sao Paulo. Flights usually cover this in 14h 39m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Sao Paulo?

    Prices for flights from Knoxville McGhee Tyson Airport to Sao Paulo are updated daily.

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Sao Paulo?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Sao Paulo.

  • What documentation or ID do you need to fly to Sao Paulo?

    The required travel and health documents for your Sao Paulo trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Sao Paulo. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Sao Paulo?

Book flights to Sao Paulo if you plan to visit one of these locations
Santos
Guarujá

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Sao Paulo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Sao Paulo from Knoxville.

Can I find flights from Knoxville to Sao Paulo with flexible booking policies on momondo?

All flight searches from Knoxville to Sao Paulo on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Knoxville to Sao Paulo?

Once all potential Knoxville to Sao Paulo flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Knoxville to Sao Paulo right now. Can momondo alert me if prices change?

Price alerts on flights to Sao Paulo from Knoxville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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Find better results for your trip to Brazil

Fly into one of these airports located in Sao Paulo

Airports listed have a maximum distance of 48.9 mi from Sao Paulo
Sao Paulo Congonhas Airport
Sao Paulo Guarulhos Intl Airport
Sao Paulo Viracopos Airport