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Cheap flights from Knoxville to Sao Paulo from $585

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Sao Paulo departing on 3/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
5:27 pm - 7:15 am
TYS
-
GRU
35h 48m1 stop
United Airlines Logo
10:20 pm - 8:46 pm
GRU
-
TYS
23h 26m1 stop
$1,048United Airlines
dom., mar. 1 - mié., abr. 1
LATAM Airlines Logo
4:03 pm - 9:35 am
TYS
-
GRU
15h 32m1 stop
LATAM Airlines Logo
11:45 pm - 6:20 pm
GRU
-
TYS
19h 35m2 stops
$1,064LATAM Airlines
dom., mar. 1 - mié., abr. 1
United Airlines Logo
4:55 pm - 9:30 am
TYS
-
GRU
14h 35m1 stop
United Airlines Logo
10:15 pm - 7:55 pm
GRU
-
TYS
23h 40m1 stop
$1,270United Airlines
sáb., feb. 14 - mié., feb. 18
United Airlines Logo
4:55 pm - 9:30 am
TYS
-
GRU
14h 35m1 stop
United Airlines Logo
10:25 pm - 1:20 pm
GRU
-
TYS
16h 55m2 stops
$1,275United Airlines
sáb., feb. 14 - mié., feb. 18

United Airlines flights from Knoxville to Sao Paulo

Our best United Airlines deals on Knoxville to Sao Paulo flight tickets
United Airlines
Mar 1
TYS5:27 pmKnoxville McGhee Tyson
35h 48m
1 stop
GRU7:15 amSao Paulo Guarulhos Intl
Apr 1
GRU10:20 pmSao Paulo Guarulhos Intl
23h 26m
1 stop
TYS8:46 pmKnoxville McGhee Tyson
$1,048
Find similar
United Airlines
Feb 14
TYS4:55 pmKnoxville McGhee Tyson
14h 35m
1 stop
GRU9:30 amSao Paulo Guarulhos Intl
Feb 18
GRU10:15 pmSao Paulo Guarulhos Intl
23h 40m
1 stop
TYS7:55 pmKnoxville McGhee Tyson
$1,270
Find similar
United Airlines
Feb 14
TYS4:55 pmKnoxville McGhee Tyson
14h 35m
1 stop
GRU9:30 amSao Paulo Guarulhos Intl
Feb 18
GRU10:25 pmSao Paulo Guarulhos Intl
16h 55m
2 stops
TYS1:20 pmKnoxville McGhee Tyson
$1,275
Find similar

LATAM Airlines flights from Knoxville to Sao Paulo

Our best LATAM Airlines deals on Knoxville to Sao Paulo flight tickets
LATAM Airlines
Mar 1
TYS4:03 pmKnoxville McGhee Tyson
15h 32m
1 stop
GRU9:35 amSao Paulo Guarulhos Intl
Apr 1
GRU11:45 pmSao Paulo Guarulhos Intl
19h 35m
2 stops
TYS6:20 pmKnoxville McGhee Tyson
$1,064
Find similar
LATAM Airlines
Dec 12
TYS7:59 pmKnoxville McGhee Tyson
31h 46m
2 stops
GRU5:45 amSao Paulo Guarulhos Intl
Jan 2
GRU8:15 amSao Paulo Guarulhos Intl
28h 16m
2 stops
TYS10:31 amKnoxville McGhee Tyson
$2,355
Find similar
LATAM Airlines
Dec 12
TYS11:26 amKnoxville McGhee Tyson
31h 34m
3 stops
GRU9:00 pmSao Paulo Guarulhos Intl
Jan 2
GRU11:55 pmSao Paulo Guarulhos Intl
20h 19m
2 stops
TYS6:14 pmKnoxville McGhee Tyson
$2,742
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Sao Paulo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated diciembre 11, 2025.
Use the filters below to find and compare flights from Knoxville to Sao Paulo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

dom. 3/1

5:27 pm-7:15 am

1 stop35h 48m

Sao Paulo Guarulhos Intl

mié. 4/1

10:20 pm-8:46 pm

1 stop23h 26m

$1,048

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

dom. 3/1

4:03 pm-9:35 am

1 stop15h 32m

Sao Paulo Guarulhos Intl

mié. 4/1

11:45 pm-6:20 pm

2 stops19h 35m

$1,064

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

sáb. 2/14

4:55 pm-9:30 am

1 stop14h 35m

Sao Paulo Guarulhos Intl

mié. 2/18

10:15 pm-7:55 pm

1 stop23h 40m

$1,270

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

sáb. 2/14

4:55 pm-9:30 am

1 stop14h 35m

Sao Paulo Guarulhos Intl

mié. 2/18

10:25 pm-1:20 pm

2 stops16h 55m

$1,275

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

vie. 3/27

5:01 pm-9:35 am

1 stop15h 34m

$585

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

vie. 3/27

7:25 pm-10:20 am

1 stop13h 55m

$595

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

vie. 3/27

7:00 am-10:20 am

3 stops26h 20m

$755

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

vie. 3/27

7:00 am-10:20 am

3 stops26h 20m

$756

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Sao Paulo from

How to get the cheapest flight ticket from Knoxville to Sao Paulo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest time of day to depart on your flight to Sao Paulo?

At noon is the cheapest time of day to fly from Knoxville to Sao Paulo when you can find flight prices for as low as $862. Flying to Sao Paulo at noon is an ideal time because this is during off-peak travel hours. Flights to Sao Paulo are more costly in the afternoon, with an average ticket price of $1,177. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

When to book flights from Knoxville to Sao Paulo

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Sao Paulo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Sao Paulo (TYS to SAO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Sao Paulo

Fastest flight time

11h 36m

Direct flights

None
The fastest flight from Knoxville to Sao Paulo takes 11h 36m
There are no direct flights from Knoxville to Sao Paulo. There are no popular flight routes from Knoxville to Sao Paulo.
Search flight deals

  • How far is Knoxville McGhee Tyson to Sao Paulo by plane?

    There are 4775.1 mi between Knoxville McGhee Tyson and Sao Paulo. Flights usually cover this in 11h 36m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Sao Paulo?

    Prices for flights from Knoxville McGhee Tyson Airport to Sao Paulo are updated daily.

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Sao Paulo?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Sao Paulo.

  • What documentation or ID do you need to fly to Sao Paulo?

    The required travel and health documents for your Sao Paulo trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Sao Paulo. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Sao Paulo?

Book flights to Sao Paulo if you plan to visit one of these locations
Santos
Guarujá

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Sao Paulo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Sao Paulo from Knoxville.

Can I find flights from Knoxville to Sao Paulo with flexible booking policies on momondo?

All flight searches from Knoxville to Sao Paulo on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Knoxville to Sao Paulo?

Once all potential Knoxville to Sao Paulo flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Knoxville to Sao Paulo right now. Can momondo alert me if prices change?

Price alerts on flights to Sao Paulo from Knoxville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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sáb. 1/10
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Find better results for your trip to Brazil

Fly into one of these airports located in Sao Paulo

Airports listed have a maximum distance of 48.9 mi from Sao Paulo
Sao Paulo Congonhas Airport
Sao Paulo Guarulhos Intl Airport
Sao Paulo Viracopos Airport