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Cheap flights from Knoxville to San Antonio from $133

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to San Antonio departing on 2/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Knoxville to San Antonio

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
7:00 am - 12:27 pm
TYS
-
SAT
6h 27m
1 stop
United Airlines Logo
2:15 pm - 8:47 pm
SAT
-
TYS
5h 32m
1 stop
$217United Airlines
Wed, Mar 11 - Tue, Mar 17
Southwest Logo
6:35 am - 10:20 am
TYS
-
SAT
4h 45m
1 stop
Southwest Logo
10:55 am - 8:05 pm
SAT
-
TYS
8h 10m
2 stops
$222Southwest
Wed, Mar 11 - Tue, Mar 17
Southwest Logo
6:35 am - 1:40 pm
TYS
-
SAT
8h 05m
2 stops
Southwest Logo
11:10 am - 8:05 pm
SAT
-
TYS
7h 55m
2 stops
$227Southwest
Wed, Mar 11 - Tue, Mar 17
Delta Logo
6:41 pm - 10:28 pm
TYS
-
SAT
4h 47m
1 stop
Delta Logo
5:30 am - 11:08 am
SAT
-
TYS
4h 38m
1 stop
$235Delta
Thu, Feb 19 - Sat, Feb 21
Multiple Airlines Logo
3:50 pm - 9:30 am
TYS
-
SAT
18h 40m
1 stop
Multiple Airlines Logo
8:20 pm - 6:06 pm
SAT
-
TYS
20h 46m
1 stop
$242Multiple Airlines
Wed, Feb 25 - Thu, Feb 26
Delta Logo
7:20 pm - 12:14 am
TYS
-
SAT
5h 54m
1 stop
Delta Logo
12:50 pm - 9:28 pm
SAT
-
TYS
7h 38m
1 stop
$252Delta
Fri, May 15 - Mon, May 18
Multiple Airlines Logo
9:36 pm - 9:30 am
TYS
-
SAT
12h 54m
1 stop
Multiple Airlines Logo
8:24 pm - 6:31 pm
SAT
-
TYS
21h 07m
1 stop
$253Multiple Airlines
Fri, Feb 27 - Sun, Mar 1
Multiple Airlines Logo
6:30 am - 4:15 pm
TYS
-
SAT
34h 45m
2 stops
Multiple Airlines Logo
10:26 am - 11:27 pm
SAT
-
TYS
12h 01m
1 stop
$264Multiple Airlines
Thu, Feb 26 - Thu, Mar 5
Multiple Airlines Logo
7:00 am - 4:15 pm
TYS
-
SAT
34h 15m
2 stops
Multiple Airlines Logo
1:57 pm - 4:24 pm
SAT
-
TYS
25h 27m
1 stop
$266Multiple Airlines
Thu, Feb 19 - Mon, Feb 23
American Airlines Logo
5:47 pm - 10:55 pm
TYS
-
SAT
6h 08m
1 stop
American Airlines Logo
6:00 am - 11:31 am
SAT
-
TYS
4h 31m
1 stop
$269American Airlines
Fri, Feb 27 - Sun, Mar 1

United Airlines flights from Knoxville to San Antonio

Our best United Airlines deals on Knoxville to San Antonio flight tickets
United Airlines
Mar 11
TYS7:00 amKnoxville McGhee Tyson
6h 27m
1 stop
SAT12:27 pmSan Antonio
Mar 17
SAT2:15 pmSan Antonio
5h 32m
1 stop
TYS8:47 pmKnoxville McGhee Tyson
$217
United Airlines
Apr 2
TYS7:00 amKnoxville McGhee Tyson
9h 46m
2 stops
SAT3:46 pmSan Antonio
Apr 4
SAT2:14 pmSan Antonio
4h 42m
1 stop
TYS7:56 pmKnoxville McGhee Tyson
$274
United Airlines
Feb 10
TYS4:55 pmKnoxville McGhee Tyson
5h 26m
1 stop
SAT9:21 pmSan Antonio
Feb 14
SAT11:43 amSan Antonio
7h 54m
2 stops
TYS8:37 pmKnoxville McGhee Tyson
$304

Southwest flights from Knoxville to San Antonio

Our best Southwest deals on Knoxville to San Antonio flight tickets
Southwest
Mar 11
TYS6:35 amKnoxville McGhee Tyson
4h 45m
1 stop
SAT10:20 amSan Antonio
Mar 17
SAT10:55 amSan Antonio
8h 10m
2 stops
TYS8:05 pmKnoxville McGhee Tyson
$222
Southwest
Mar 11
TYS6:35 amKnoxville McGhee Tyson
8h 05m
2 stops
SAT1:40 pmSan Antonio
Mar 17
SAT11:10 amSan Antonio
7h 55m
2 stops
TYS8:05 pmKnoxville McGhee Tyson
$227
Southwest
Apr 2
TYS3:45 pmKnoxville McGhee Tyson
8h 55m
2 stops
SAT11:40 pmSan Antonio
Apr 4
SAT5:40 amSan Antonio
6h 30m
2 stops
TYS1:10 pmKnoxville McGhee Tyson
$307

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from Knoxville to San Antonio that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleSan Antonio

TYS - SAT

TYSSAT

Knoxville McGhee Tyson

Wed 3/11

7:00 am-12:27 pm

1 stop6h 27m

San Antonio

Tue 3/17

2:15 pm-8:47 pm

1 stop5h 32m

$217

KnoxvilleSan Antonio

TYS - SAT

TYSSAT

Knoxville McGhee Tyson

Wed 3/11

6:35 am-10:20 am

1 stop4h 45m

San Antonio

Tue 3/17

10:55 am-8:05 pm

2 stops8h 10m

$222

KnoxvilleSan Antonio

TYS - SAT

TYSSAT

Knoxville McGhee Tyson

Wed 3/11

6:35 am-1:40 pm

2 stops8h 05m

San Antonio

Tue 3/17

11:10 am-8:05 pm

2 stops7h 55m

$227

KnoxvilleSan Antonio

TYS - SAT

TYSSAT

Knoxville McGhee Tyson

Thu 2/19

6:41 pm-10:28 pm

1 stop4h 47m

San Antonio

Sat 2/21

5:30 am-11:08 am

1 stop4h 38m

$235

KnoxvilleSan Antonio

TYS - SAT

TYSSAT

Knoxville McGhee Tyson

Wed 2/25

3:50 pm-9:30 am

1 stop18h 40m

San Antonio

Thu 2/26

8:20 pm-6:06 pm

1 stop20h 46m

$242

KnoxvilleSan Antonio

TYS - SAT

TYSSAT

Knoxville McGhee Tyson

Fri 5/15

7:20 pm-12:14 am

1 stop5h 54m

San Antonio

Mon 5/18

12:50 pm-9:28 pm

1 stop7h 38m

$252

KnoxvilleSan Antonio

TYS - SAT

TYSSAT

Knoxville McGhee Tyson

Fri 2/27

9:36 pm-9:30 am

1 stop12h 54m

San Antonio

Sun 3/1

8:24 pm-6:31 pm

1 stop21h 07m

$253

KnoxvilleSan Antonio

TYS - SAT

TYSSAT

Knoxville McGhee Tyson

Thu 2/26

6:30 am-4:15 pm

2 stops34h 45m

San Antonio

Thu 3/5

10:26 am-11:27 pm

1 stop12h 01m

$264

KnoxvilleSan Antonio

TYS - SAT

TYSSAT

Knoxville McGhee Tyson

Thu 2/19

7:00 am-4:15 pm

2 stops34h 15m

San Antonio

Mon 2/23

1:57 pm-4:24 pm

1 stop25h 27m

$266

KnoxvilleSan Antonio

TYS - SAT

TYSSAT

Knoxville McGhee Tyson

Fri 2/27

5:47 pm-10:55 pm

1 stop6h 08m

San Antonio

Sun 3/1

6:00 am-11:31 am

1 stop4h 31m

$269

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Antonio from

How to get the cheapest flight ticket from Knoxville to San Antonio

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Antonio?

If you aren’t able to travel during the month of July, then book flights to San Antonio from Knoxville during September instead. Flights to San Antonio in September, while not as cheap as those in July, still average around $268.

How far in advance should I book a flight to San Antonio?

You are more likely to see cheaper flights to San Antonio from Knoxville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Antonio for around $338 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Antonio from Knoxville for as low as $257 on momondo.

How have Knoxville to San Antonio flight prices changed over time?

When to book flights from Knoxville to San Antonio

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to San Antonio according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to San Antonio (TYS to SAT) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to San Antonio

Fastest flight time

4h 23m

Direct flights

None
The fastest flight from Knoxville to San Antonio takes 4h 23m
There are no direct flights from Knoxville to San Antonio. There are no popular flight routes from Knoxville to San Antonio.
Search flight deals

  • How far is Knoxville McGhee Tyson to San Antonio by plane?

    San Antonio is 958.1 mi away from Knoxville McGhee Tyson. In terms of flight time, this usually takes a little over 4h 23m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to San Antonio Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to San Antonio Airport are updated daily.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to San Antonio Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to San Antonio Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to San Antonio Airport.

  • What documentation or ID do you need to fly to San Antonio Airport?

    The required travel and health documents for your San Antonio Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Antonio Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Knoxville to San Antonio?

Best airlines flying from Knoxville to San Antonio

Compare and see reviews for airlines that fly from Knoxville to San Antonio with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $232Free CancellationRating
7.2
11,201 reviews
Search American Airlines flights
DeltaPriceFrom $236Free CancellationRating
7.9
8,124 reviews
Search Delta flights
United AirlinesPriceFrom $237Free CancellationRating
7.4
9,212 reviews
Search United Airlines flights

Traveling to a place near San Antonio?

Book flights to San Antonio if you plan to visit one of these locations
New Braunfels
Kerrville
Boerne
Pleasanton
Schertz

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to San Antonio?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Antonio from Knoxville.

Can I find flights from Knoxville to San Antonio with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Knoxville to San Antonio flights to just show those with flexible booking policies.

How can momondo help me find flights from Knoxville to San Antonio?

momondo helps you find the best flight between Knoxville and San Antonio by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Knoxville to San Antonio right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Antonio from Knoxville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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