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Cheap flights from Des Moines to Palm Springs from $169

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Palm Springs departing on 4/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Des Moines to Palm Springs

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
5:17 pm - 8:44 pm
DSM
-
PSP
5h 27m
1 stop
United Airlines Logo
9:15 am - 4:15 pm
PSP
-
DSM
5h 00m
1 stop
$337United Airlines
Wed, Apr 8 - Sat, Apr 11
United Airlines Logo
5:30 am - 9:32 am
DSM
-
PSP
6h 02m
1 stop
United Airlines Logo
9:15 am - 9:27 pm
PSP
-
DSM
10h 12m
2 stops
$342United Airlines
Wed, Apr 8 - Sat, Apr 11
American Airlines Logo
6:23 pm - 9:53 pm
DSM
-
PSP
5h 30m
1 stop
American Airlines Logo
2:45 pm - 11:16 pm
PSP
-
DSM
6h 31m
1 stop
$347American Airlines
Thu, Apr 2 - Tue, Apr 7
United Airlines Logo
5:04 pm - 9:20 pm
DSM
-
PSP
6h 16m
1 stop
United Airlines Logo
4:27 pm - 11:42 pm
PSP
-
DSM
5h 15m
1 stop
$351United Airlines
Wed, Mar 18 - Wed, Mar 25
American Airlines Logo
6:23 pm - 9:53 pm
DSM
-
PSP
5h 30m
1 stop
American Airlines Logo
1:00 pm - 11:49 pm
PSP
-
DSM
8h 49m
2 stops
$352American Airlines
Thu, Apr 2 - Tue, Apr 7
American Airlines Logo
6:23 pm - 9:53 pm
DSM
-
PSP
5h 30m
1 stop
American Airlines Logo
2:57 pm - 11:42 pm
PSP
-
DSM
6h 45m
1 stop
$357American Airlines
Thu, Mar 19 - Fri, Mar 27
American Airlines Logo
6:23 pm - 9:53 pm
DSM
-
PSP
5h 30m
1 stop
American Airlines Logo
10:04 am - 11:49 pm
PSP
-
DSM
11h 45m
2 stops
$358American Airlines
Thu, Apr 2 - Tue, Apr 7
American Airlines Logo
6:23 pm - 9:53 pm
DSM
-
PSP
5h 30m
1 stop
American Airlines Logo
6:56 pm - 8:26 am
PSP
-
DSM
11h 30m
2 stops
$362American Airlines
Thu, Apr 2 - Mon, Apr 6
American Airlines Logo
6:23 pm - 9:53 pm
DSM
-
PSP
5h 30m
1 stop
American Airlines Logo
2:45 pm - 11:16 pm
PSP
-
DSM
6h 31m
1 stop
$363American Airlines
Thu, Apr 2 - Tue, Apr 7
Southwest Logo
5:30 am - 1:55 pm
DSM
-
PSP
10h 25m
2 stops
Southwest Logo
9:50 am - 9:55 pm
PSP
-
DSM
10h 05m
2 stops
$367Southwest
Wed, Apr 29 - Mon, May 4

American Airlines flights from Des Moines to Palm Springs

Our best American Airlines deals on Des Moines to Palm Springs flight tickets
American Airlines
Apr 2
DSM6:23 pmDes Moines
5h 30m
1 stop
PSP9:53 pmPalm Springs
Apr 7
PSP2:45 pmPalm Springs
6h 31m
1 stop
DSM11:16 pmDes Moines
$347
American Airlines
Apr 2
DSM6:23 pmDes Moines
5h 30m
1 stop
PSP9:53 pmPalm Springs
Apr 7
PSP1:00 pmPalm Springs
8h 49m
2 stops
DSM11:49 pmDes Moines
$352
American Airlines
Mar 19
DSM6:23 pmDes Moines
5h 30m
1 stop
PSP9:53 pmPalm Springs
Mar 26
PSP2:57 pmPalm Springs
6h 45m
1 stop
DSM11:42 pmDes Moines
$357

Southwest flights from Des Moines to Palm Springs

Our best Southwest deals on Des Moines to Palm Springs flight tickets
Southwest
Apr 29
DSM5:30 amDes Moines
10h 25m
2 stops
PSP1:55 pmPalm Springs
May 4
PSP9:50 amPalm Springs
10h 05m
2 stops
DSM9:55 pmDes Moines
$367
Southwest
Mar 24
DSM6:40 amDes Moines
5h 10m
1 stop
PSP9:50 amPalm Springs
Mar 28
PSP5:30 amPalm Springs
11h 45m
2 stops
DSM7:15 pmDes Moines
$388
Southwest
Mar 21
DSM12:05 pmDes Moines
12h 40m
2 stops
PSP10:45 pmPalm Springs
Mar 25
PSP10:20 amPalm Springs
8h 30m
2 stops
DSM8:50 pmDes Moines
$429

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Palm Springs that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 22, 2026.
Use the filters below to find and compare flights from Des Moines to Palm Springs that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesPalm Springs

DSM - PSP

DSMPSP

Des Moines

Wed 4/8

5:17 pm-8:44 pm

1 stop5h 27m

Palm Springs

Sat 4/11

9:15 am-4:15 pm

1 stop5h 00m

$337

Des MoinesPalm Springs

DSM - PSP

DSMPSP

Des Moines

Wed 4/8

5:30 am-9:32 am

1 stop6h 02m

Palm Springs

Sat 4/11

9:15 am-9:27 pm

2 stops10h 12m

$342

Des MoinesPalm Springs

DSM - PSP

DSMPSP

Des Moines

Thu 4/2

6:23 pm-9:53 pm

1 stop5h 30m

Palm Springs

Tue 4/7

2:45 pm-11:16 pm

1 stop6h 31m

$347

Des MoinesPalm Springs

DSM - PSP

DSMPSP

Des Moines

Wed 3/18

5:04 pm-9:20 pm

1 stop6h 16m

Palm Springs

Wed 3/25

4:27 pm-11:42 pm

1 stop5h 15m

$351

Des MoinesPalm Springs

DSM - PSP

DSMPSP

Des Moines

Thu 4/2

6:23 pm-9:53 pm

1 stop5h 30m

Palm Springs

Tue 4/7

1:00 pm-11:49 pm

2 stops8h 49m

$352

Des MoinesPalm Springs

DSM - PSP

DSMPSP

Des Moines

Thu 3/19

6:23 pm-9:53 pm

1 stop5h 30m

Palm Springs

Fri 3/27

2:57 pm-11:42 pm

1 stop6h 45m

$357

Des MoinesPalm Springs

DSM - PSP

DSMPSP

Des Moines

Thu 4/2

6:23 pm-9:53 pm

1 stop5h 30m

Palm Springs

Tue 4/7

10:04 am-11:49 pm

2 stops11h 45m

$358

Des MoinesPalm Springs

DSM - PSP

DSMPSP

Des Moines

Thu 4/2

6:23 pm-9:53 pm

1 stop5h 30m

Palm Springs

Mon 4/6

6:56 pm-8:26 am

2 stops11h 30m

$362

Des MoinesPalm Springs

DSM - PSP

DSMPSP

Des Moines

Thu 4/2

6:23 pm-9:53 pm

1 stop5h 30m

Palm Springs

Tue 4/7

2:45 pm-11:16 pm

1 stop6h 31m

$363

Des MoinesPalm Springs

DSM - PSP

DSMPSP

Des Moines

Wed 4/29

5:30 am-1:55 pm

2 stops10h 25m

Palm Springs

Mon 5/4

9:50 am-9:55 pm

2 stops10h 05m

$367

Flights are sorted by cheapest round-trip flights first.

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How to get the cheapest flight ticket from Des Moines to Palm Springs

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Palm Springs?

In general, September is the cheapest month to fly from Des Moines to Palm Springs. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $337. If you aren’t able to travel during the month of September, then book flights to Palm Springs from Des Moines during August instead. Flights to Palm Springs in August, while not as cheap as those in September, still average around $376.

When to book flights from Des Moines to Palm Springs

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Palm Springs according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Palm Springs (DSM to PSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Palm Springs

Fastest flight time

5h 27m

Direct flights

None
The fastest flight from Des Moines to Palm Springs takes 5h 27m
There are no direct flights from Des Moines to Palm Springs. There are no popular flight routes from Des Moines to Palm Springs.
Search flight deals

  • How far is Des Moines to Palm Springs by plane?

    The distance between Des Moines and Palm Springs is about 1356.2 mi. In terms of flight time, this usually takes a little over 5h 27m.

  • When did momondo last update prices for flights from Des Moines Airport to Palm Springs Airport?

    Prices for flights from Des Moines Airport to Palm Springs Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Palm Springs Airport?

  • How old do you have to be to fly from Des Moines Airport to Palm Springs Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Palm Springs Airport.

  • What documentation or ID do you need to fly to Palm Springs Airport?

    The travel and health documents required for your trip to Palm Springs Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Palm Springs Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Des Moines to Palm Springs?

Best airlines flying from Des Moines to Palm Springs

Compare and see reviews for airlines that fly from Des Moines to Palm Springs with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $289Free CancellationRating
7.4
9,341 reviews
Search United Airlines flights
American AirlinesPriceFrom $298Free CancellationRating
7.2
11,338 reviews
Search American Airlines flights
SouthwestPriceFrom $346Free CancellationRating
8.0
4,299 reviews
Search Southwest flights

Traveling to a place near Palm Springs?

Book flights to Palm Springs if you plan to visit one of these locations
Palm Desert
Indio
Desert Hot Springs
Rancho Mirage
Joshua Tree
Idyllwild
La Quinta
Indian Wells
Cathedral City
Banning
Coachella
Twentynine Palms
Cabazon
Yucca Valley
Pioneertown

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Palm Springs?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Des Moines to Palm Springs. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Des Moines to Palm Springs with flexible booking policies on momondo?

Flights from Des Moines to Palm Springs with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Des Moines to Palm Springs?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Palm Springs from Des Moines.

I’m not ready to book a flight from Des Moines to Palm Springs right now. Can momondo alert me if prices change?

Price alerts on flights to Palm Springs from Des Moines are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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