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Cheap flights from Des Moines to Palm Springs from $172

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Palm Springs departing on 2/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Des Moines to Palm Springs

Cheap round-trip flights

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American Airlines Logo
5:24 am - 11:49 amDSM-PSP
8h 25m1 stop
American Airlines Logo
9:47 am - 5:33 pmPSP-DSM
5h 46m1 stop
$347American Airlines
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Wed, Jan 14 - Sun, Jan 18
Frontier Logo
7:46 pm - 11:02 amDSM-PSP
17h 16m1 stop
Frontier Logo
11:47 am - 1:15 pmPSP-DSM
23h 28m1 stop
$349Frontier
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Fri, Nov 21 - Tue, Nov 25
United Airlines Logo
5:09 pm - 9:08 pmDSM-PSP
5h 59m1 stop
United Airlines Logo
11:30 am - 8:34 pmPSP-DSM
7h 04m1 stop
$351United Airlines
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Wed, Jan 7 - Tue, Jan 13
Southwest Logo
12:05 pm - 7:50 pmDSM-PSP
9h 45m2 stops
Southwest Logo
5:45 am - 2:40 pmPSP-DSM
6h 55m1 stop
$352Southwest
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Wed, Jan 14 - Tue, Jan 20
Delta Logo
6:24 am - 4:19 pmDSM-PSP
11h 55m2 stops
Delta Logo
1:29 pm - 10:31 pmPSP-DSM
7h 02m1 stop
$356Delta
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Wed, Jan 7 - Tue, Jan 13
United Airlines Logo
8:00 am - 5:18 pmDSM-PSP
11h 18m2 stops
United Airlines Logo
10:17 am - 8:34 pmPSP-DSM
8h 17m2 stops
$361United Airlines
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Wed, Jan 7 - Tue, Jan 13
Southwest Logo
11:40 am - 9:20 pmDSM-PSP
11h 40m2 stops
Southwest Logo
5:45 am - 7:20 pmPSP-DSM
11h 35m2 stops
$368Southwest
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Fri, Feb 20 - Tue, Feb 24
Multiple Airlines Logo
7:46 pm - 5:36 pmDSM-PSP
23h 50m2 stops
Multiple Airlines Logo
11:47 am - 1:15 pmPSP-DSM
23h 28m1 stop
$381Multiple Airlines
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Fri, Nov 21 - Tue, Nov 25
Delta Logo
6:50 am - 12:47 pmDSM-PSP
7h 57m1 stop
Delta Logo
12:37 pm - 10:34 pmPSP-DSM
7h 57m1 stop
$445Delta
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Mon, Dec 1 - Thu, Dec 4
Multiple Airlines Logo
3:48 pm - 5:36 pmDSM-PSP
27h 48m2 stops
Multiple Airlines Logo
5:36 pm - 9:09 pmPSP-DSM
25h 33m2 stops
$522Multiple Airlines
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Fri, Nov 21 - Tue, Nov 25

American Airlines flights from Des Moines to Palm Springs

Our best American Airlines deals on Des Moines to Palm Springs flight tickets
American Airlines
Jan 14
DSM5:24 amDes Moines
8h 25m
1 stop
PSP11:49 amPalm Springs
Jan 18
PSP9:47 amPalm Springs
5h 46m
1 stop
DSM5:33 pmDes Moines
$347
Find similar
American Airlines
Jan 14
DSM4:00 pmDes Moines
8h 34m
1 stop
PSP10:34 pmPalm Springs
Jan 18
PSP9:47 amPalm Springs
5h 46m
1 stop
DSM5:33 pmDes Moines
$385
Find similar
American Airlines
Feb 21
DSM3:25 pmDes Moines
7h 43m
1 stop
PSP9:08 pmPalm Springs
Feb 25
PSP12:45 pmPalm Springs
7h 41m
2 stops
DSM10:26 pmDes Moines
$386
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Southwest flights from Des Moines to Palm Springs

Our best Southwest deals on Des Moines to Palm Springs flight tickets
Southwest
Jan 14
DSM12:05 pmDes Moines
9h 45m
2 stops
PSP7:50 pmPalm Springs
Jan 20
PSP5:45 amPalm Springs
6h 55m
1 stop
DSM2:40 pmDes Moines
$352
Find similar
Southwest
Feb 20
DSM11:40 amDes Moines
11h 40m
2 stops
PSP9:20 pmPalm Springs
Feb 24
PSP5:45 amPalm Springs
11h 35m
2 stops
DSM7:20 pmDes Moines
$368
Find similar
Southwest
Jan 19
DSM6:25 amDes Moines
5h 25m
1 stop
PSP9:50 amPalm Springs
Jan 26
PSP5:45 amPalm Springs
6h 55m
1 stop
DSM2:40 pmDes Moines
$371
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Palm Springs that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Des Moines to Palm Springs that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesPalm Springs

DSM - PSP

DSMPSP

Des Moines

Wed 1/14

5:24 am-11:49 am

1 stop8h 25m

Palm Springs

Sun 1/18

9:47 am-5:33 pm

1 stop5h 46m

$347

Des MoinesPalm Springs

DSM - PSP

DSMPSP

Des Moines

Fri 11/21

7:46 pm-11:02 am

1 stop17h 16m

Palm Springs

Tue 11/25

11:47 am-1:15 pm

1 stop23h 28m

$349

Des MoinesPalm Springs

DSM - PSP

DSMPSP

Des Moines

Wed 1/7

5:09 pm-9:08 pm

1 stop5h 59m

Palm Springs

Tue 1/13

11:30 am-8:34 pm

1 stop7h 04m

$351

Des MoinesPalm Springs

DSM - PSP

DSMPSP

Des Moines

Wed 1/14

12:05 pm-7:50 pm

2 stops9h 45m

Palm Springs

Tue 1/20

5:45 am-2:40 pm

1 stop6h 55m

$352

Des MoinesPalm Springs

DSM - PSP

DSMPSP

Des Moines

Wed 1/7

6:24 am-4:19 pm

2 stops11h 55m

Palm Springs

Tue 1/13

1:29 pm-10:31 pm

1 stop7h 02m

$356

Des MoinesPalm Springs

DSM - PSP

DSMPSP

Des Moines

Wed 1/7

8:00 am-5:18 pm

2 stops11h 18m

Palm Springs

Tue 1/13

10:17 am-8:34 pm

2 stops8h 17m

$361

Des MoinesPalm Springs

DSM - PSP

DSMPSP

Des Moines

Fri 2/20

11:40 am-9:20 pm

2 stops11h 40m

Palm Springs

Tue 2/24

5:45 am-7:20 pm

2 stops11h 35m

$368

Des MoinesPalm Springs

DSM - PSP

DSMPSP

Des Moines

Fri 11/21

7:46 pm-5:36 pm

2 stops23h 50m

Palm Springs

Tue 11/25

11:47 am-1:15 pm

1 stop23h 28m

$381

Des MoinesPalm Springs

DSM - PSP

DSMPSP

Des Moines

Mon 12/1

6:50 am-12:47 pm

1 stop7h 57m

Palm Springs

Thu 12/4

12:37 pm-10:34 pm

1 stop7h 57m

$445

Des MoinesPalm Springs

DSM - PSP

DSMPSP

Des Moines

Fri 11/21

3:48 pm-5:36 pm

2 stops27h 48m

Palm Springs

Tue 11/25

5:36 pm-9:09 pm

2 stops25h 33m

$522

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Palm Springs from

How to get the cheapest flight ticket from Des Moines to Palm Springs

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Palm Springs?

In general, September is the cheapest month to fly from Des Moines to Palm Springs. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $337. If you aren’t able to travel during the month of September, then book flights to Palm Springs from Des Moines during August instead. Flights to Palm Springs in August, while not as cheap as those in September, still average around $376.

What is the cheapest day to depart on your flight to Palm Springs?

The cheapest day to depart from Des Moines to Palm Springs is on a Tuesday when prices can be found for as low as $341. Flights from Des Moines to Palm Springs on a Thursday will generally be more expensive and average around $489. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Palm Springs?

Our data shows that the cheapest Des Moines to Palm Springs flights are usually those with departure times at noon. Our users have found flights to Palm Springs at noon for as low as $376. In contrast, the most expensive time of day to depart to Palm Springs is in the morning when prices are around $459.

How far in advance should I book a flight to Palm Springs?

You are more likely to see cheaper flights to Palm Springs from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Palm Springs for around $463 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Palm Springs from Des Moines for as low as $408 on momondo.

When to book flights from Des Moines to Palm Springs

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Palm Springs according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Palm Springs (DSM to PSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Palm Springs

Direct flights

None
There are no direct flights from Des Moines to Palm Springs. There are no popular flight routes from Des Moines to Palm Springs.
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  • How far is Des Moines to Palm Springs by plane?

    The distance between Des Moines and Palm Springs is about 1356.2 mi. In terms of flight time, this usually takes a little over 5h 25m.

  • When did momondo last update prices for flights from Des Moines Airport to Palm Springs Airport?

    Prices for flights from Des Moines Airport to Palm Springs Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Palm Springs Airport?

  • How old do you have to be to fly from Des Moines Airport to Palm Springs Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Palm Springs Airport.

  • What documentation or ID do you need to fly to Palm Springs Airport?

    The travel and health documents required for your trip to Palm Springs Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Palm Springs Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Des Moines to Palm Springs?

Best airlines flying from Des Moines to Palm Springs

Compare and see reviews for airlines that fly from Des Moines to Palm Springs with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $324Free CancellationRating
7.2
11,040 reviews
Search American Airlines flights
United AirlinesPriceFrom $335Free CancellationRating
7.4
9,007 reviews
Search United Airlines flights
SouthwestPriceFrom $371Free CancellationRating
8.0
4,241 reviews
Search Southwest flights

Traveling to a place near Palm Springs?

Book flights to Palm Springs if you plan to visit one of these locations
Palm Desert
Desert Hot Springs
Indio
Rancho Mirage
La Quinta
Idyllwild
Joshua Tree
Indian Wells
Cathedral City
Coachella
Banning
Twentynine Palms
Cabazon
Yucca Valley
Pioneertown

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Palm Springs?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Des Moines to Palm Springs. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Des Moines to Palm Springs with flexible booking policies on momondo?

Flights from Des Moines to Palm Springs with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Des Moines to Palm Springs?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Palm Springs from Des Moines.

I’m not ready to book a flight from Des Moines to Palm Springs right now. Can momondo alert me if prices change?

Price alerts on flights to Palm Springs from Des Moines are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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