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Cheap flights from Des Moines to Jacksonville from $59

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Jacksonville departing on 8/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Des Moines to Jacksonville

Cheap round-trip flights

Allegiant Air Logo
6:30 am - 10:13 amDSM-JAX
2h 43mnonstop
Allegiant Air Logo
11:03 am - 1:01 pmJAX-DSM
2h 58mnonstop
$82Allegiant Air
Find Deal
jue., sep. 4 - dom., sep. 7
Allegiant Air Logo
6:30 am - 10:07 amDSM-JAX
2h 37mnonstop
Allegiant Air Logo
10:57 am - 12:49 pmJAX-DSM
2h 52mnonstop
$86Allegiant Air
Find Deal
dom., ago. 24 - dom., ago. 31
Delta Logo
7:15 am - 2:22 pmDSM-JAX
6h 07m1 stop
Delta Logo
6:44 pm - 10:43 pmJAX-DSM
4h 59m1 stop
$372Delta
Find Deal
vie., sep. 5 - dom., sep. 7
Delta Logo
2:49 pm - 11:59 pmDSM-JAX
8h 10m2 stops
Delta Logo
6:44 pm - 10:43 pmJAX-DSM
4h 59m1 stop
$377Delta
Find Deal
vie., sep. 5 - dom., sep. 7
American Airlines Logo
6:00 am - 12:51 pmDSM-JAX
5h 51m1 stop
American Airlines Logo
7:22 am - 1:51 pmJAX-DSM
7h 29m1 stop
$387American Airlines
Find Deal
vie., sep. 26 - lun., sep. 29
American Airlines Logo
5:00 am - 2:55 pmDSM-JAX
8h 55m2 stops
American Airlines Logo
7:05 pm - 11:45 pmJAX-DSM
5h 40m1 stop
$392American Airlines
Find Deal
vie., sep. 26 - lun., sep. 29
Southwest Logo
6:10 am - 11:25 amDSM-JAX
4h 15m1 stop
Southwest Logo
12:05 pm - 9:45 pmJAX-DSM
10h 40m2 stops
$402Southwest
Find Deal
dom., ago. 24 - dom., ago. 31
Southwest Logo
6:10 am - 2:35 pmDSM-JAX
7h 25m2 stops
Southwest Logo
12:05 pm - 9:45 pmJAX-DSM
10h 40m2 stops
$407Southwest
Find Deal
dom., ago. 24 - dom., ago. 31
United Airlines Logo
1:45 pm - 11:40 pmDSM-JAX
8h 55m2 stops
United Airlines Logo
7:25 am - 2:16 pmJAX-DSM
7h 51m1 stop
$684United Airlines
Find Deal
jue., ago. 14 - dom., ago. 17
United Airlines Logo
2:57 pm - 11:40 pmDSM-JAX
7h 43m1 stop
United Airlines Logo
2:00 pm - 9:47 pmJAX-DSM
8h 47m2 stops
$687United Airlines
Find Deal
vie., ago. 15 - sáb., ago. 16

Allegiant Air flights from Des Moines to Jacksonville

Our best Allegiant Air deals on Des Moines to Jacksonville flight tickets
Allegiant Air
Sep 4
DSM6:30 amDes Moines
2h 43m
JAX10:13 amJacksonville
Sep 7
JAX11:03 amJacksonville
2h 58m
DSM1:01 pmDes Moines
$82
Find similar
Allegiant Air
Aug 24
DSM6:30 amDes Moines
2h 37m
JAX10:07 amJacksonville
Aug 31
JAX10:57 amJacksonville
2h 52m
DSM12:49 pmDes Moines
$86
Find similar
Allegiant Air
Sep 4
DSM6:30 amDes Moines
2h 43m
JAX10:13 amJacksonville
Sep 11
JAX9:20 amJacksonville
24h 34m
2 stops
DSM8:54 amDes Moines
$220
Find similar

Delta flights from Des Moines to Jacksonville

Our best Delta deals on Des Moines to Jacksonville flight tickets
Delta
Sep 5
DSM7:15 amDes Moines
6h 07m
1 stop
JAX2:22 pmJacksonville
Sep 7
JAX6:44 pmJacksonville
4h 59m
1 stop
DSM10:43 pmDes Moines
$372
Find similar
Delta
Sep 5
DSM2:49 pmDes Moines
8h 10m
2 stops
JAX11:59 pmJacksonville
Sep 7
JAX6:44 pmJacksonville
4h 59m
1 stop
DSM10:43 pmDes Moines
$377
Find similar
Delta
Sep 4
DSM2:49 pmDes Moines
8h 10m
2 stops
JAX11:59 pmJacksonville
Sep 7
JAX5:20 amJacksonville
9h 49m
2 stops
DSM2:09 pmDes Moines
$382
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Jacksonville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated julio 29, 2025.
Use the filters below to find and compare flights from Des Moines to Jacksonville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

jue. 9/4

6:30 am-10:13 am

Nonstop2h 43m

Jacksonville

dom. 9/7

11:03 am-1:01 pm

Nonstop2h 58m

$82

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

dom. 8/24

6:30 am-10:07 am

Nonstop2h 37m

Jacksonville

dom. 8/31

10:57 am-12:49 pm

Nonstop2h 52m

$86

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

vie. 9/5

7:15 am-2:22 pm

1 stop6h 07m

Jacksonville

dom. 9/7

6:44 pm-10:43 pm

1 stop4h 59m

$372

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

vie. 9/5

2:49 pm-11:59 pm

2 stops8h 10m

Jacksonville

dom. 9/7

6:44 pm-10:43 pm

1 stop4h 59m

$377

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

vie. 9/26

6:00 am-12:51 pm

1 stop5h 51m

Jacksonville

lun. 9/29

7:22 am-1:51 pm

1 stop7h 29m

$387

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

vie. 9/26

5:00 am-2:55 pm

2 stops8h 55m

Jacksonville

lun. 9/29

7:05 pm-11:45 pm

1 stop5h 40m

$392

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

dom. 8/24

6:10 am-11:25 am

1 stop4h 15m

Jacksonville

dom. 8/31

12:05 pm-9:45 pm

2 stops10h 40m

$402

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

dom. 8/24

6:10 am-2:35 pm

2 stops7h 25m

Jacksonville

dom. 8/31

12:05 pm-9:45 pm

2 stops10h 40m

$407

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

jue. 8/14

1:45 pm-11:40 pm

2 stops8h 55m

Jacksonville

dom. 8/17

7:25 am-2:16 pm

1 stop7h 51m

$684

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

vie. 8/15

2:57 pm-11:40 pm

1 stop7h 43m

Jacksonville

sáb. 8/16

2:00 pm-9:47 pm

2 stops8h 47m

$687

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Jacksonville from

How to get the cheapest flight ticket from Des Moines to Jacksonville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Jacksonville?

If you are unable to visit Jacksonville during the month of July, then departing from Des Moines during the month August is also very affordable. Most momondo users find prices during this month for around $286.

What is the cheapest day to depart on your flight to Jacksonville?

According to our data, Sunday is the cheapest day to fly to Jacksonville from Des Moines. The lowest ticket price found for a Sunday departure recently was $90. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. On the other hand, Monday is the most expensive day to depart from Des Moines because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $513.

What is the cheapest time of day to depart on your flight to Jacksonville?

Flying to Jacksonville from Des Moines in the morning is the least expensive time of day to depart. momondo users have found prices as low as $90 when looking at flights departing in the morning. Flights to Jacksonville are more costly in the afternoon, with an average ticket price of $397. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Des Moines to Jacksonville flight route?

Fly from Des Moines to Jacksonville for the best Des Moines - Jacksonville flight prices

How far in advance should I book a flight to Jacksonville?

You are more likely to see cheaper flights to Jacksonville from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Jacksonville for around $347 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Jacksonville from Des Moines for as low as $226 on momondo.

What cabin class options are available on Des Moines to Jacksonville flights?

There are 1 cabin classes available to choose from on Des Moines to Jacksonville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Des Moines to Jacksonville flight prices changed over time?

As of July 2025, prices for Des Moines to Jacksonville flights are approximately 185% more expensive when compared to flights at the same time last year.

When to book flights from Des Moines to Jacksonville

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Jacksonville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Jacksonville (DSM to JAX) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Jacksonville

Best Price Found

$59

Fastest flight time

2h 37m

Direct flights

Mon and Fri

Airports in Jacksonville

1 airport
The best one-way flight to Jacksonville from Des Moines in the past 72 hours is $59. The best round-trip flight deal from Des Moines to Jacksonville found on momondo in the last 72 hours is $82.
The fastest flight from Des Moines to Jacksonville takes 2h 37m
Direct flights go from Des Moines to Jacksonville on Monday and Friday. The only airline offering direct flights is Allegiant Air.
There is 1 airport near Jacksonville: Jacksonville (JAX)
Search flight deals

  • How far is Des Moines to Jacksonville by plane?

    There are 1023.3 mi between Des Moines and Jacksonville. In terms of flight time, this usually takes a little over 2h 37m.

  • When did momondo last update prices for flights from Des Moines Airport to Jacksonville Airport?

    Prices for flights from Des Moines Airport to Jacksonville Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Jacksonville Airport?

  • How old do you have to be to fly from Des Moines Airport to Jacksonville Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Jacksonville Airport.

  • What documentation or ID do you need to fly to Jacksonville Airport?

    The travel and health documents required for your trip to Jacksonville Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Jacksonville Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Des Moines to Jacksonville?

  • What is the most popular airline from Des Moines to Jacksonville?

Best airlines flying from Des Moines to Jacksonville

Compare and see reviews for airlines that fly from Des Moines to Jacksonville with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $81Free CancellationRating
7.2
703 reviews
Search Allegiant Air flights
DeltaPriceFrom $276Free CancellationRating
8.0
7,977 reviews
Search Delta flights
American AirlinesPriceFrom $301Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
SouthwestPriceFrom $308Free CancellationRating
8.0
4,238 reviews
Search Southwest flights
United AirlinesPriceFrom $316Free CancellationRating
7.4
8,899 reviews
Search United Airlines flights

Traveling to a place near Jacksonville?

Book flights to Jacksonville if you plan to visit one of these locations
Fernandina Beach
Jacksonville Beach
Orange Park
Ponte Vedra Beach
Kingsland
Waycross
Atlantic Beach
Neptune Beach
St Johns
Yulee
Cumberland Island

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Jacksonville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Des Moines to Jacksonville. momondo saves you time and could save you money on your trip.

Can I find flights from Des Moines to Jacksonville with flexible booking policies on momondo?

All flight searches from Des Moines to Jacksonville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Des Moines to Jacksonville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Des Moines to Jacksonville.

I’m not ready to book a flight from Des Moines to Jacksonville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Des Moines to Jacksonville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Jacksonville and let you know when they change.

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