Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Des Moines to Jacksonville from $119

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Jacksonville departing on 12/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Des Moines to Jacksonville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:54 am - 1:33 pm
DSM
-
JAX
5h 39m1 stop
Delta Logo
3:15 pm - 9:24 pm
JAX
-
DSM
7h 09m1 stop
$287Delta
Sat, Jan 17 - Sat, Jan 24
American Airlines Logo
1:16 pm - 11:26 pm
DSM
-
JAX
9h 10m2 stops
American Airlines Logo
11:53 am - 4:24 pm
JAX
-
DSM
5h 31m1 stop
$292American Airlines
Sat, Jan 17 - Sat, Jan 24
American Airlines Logo
6:00 am - 3:41 pm
DSM
-
JAX
8h 41m2 stops
American Airlines Logo
6:00 am - 12:46 pm
JAX
-
DSM
7h 46m2 stops
$297American Airlines
Sat, Jan 17 - Sat, Jan 24
American Airlines Logo
4:25 pm - 10:09 pm
DSM
-
JAX
4h 44m1 stop
American Airlines Logo
6:00 am - 12:46 pm
JAX
-
DSM
7h 46m2 stops
$303American Airlines
Thu, Jan 15 - Sun, Jan 18
American Airlines Logo
6:00 am - 1:49 pm
DSM
-
JAX
6h 49m2 stops
American Airlines Logo
6:00 am - 12:46 pm
JAX
-
DSM
7h 46m2 stops
$308American Airlines
Thu, Jan 15 - Sun, Jan 18
United Airlines Logo
3:04 pm - 9:47 pm
DSM
-
JAX
5h 43m1 stop
United Airlines Logo
2:40 pm - 9:50 pm
JAX
-
DSM
8h 10m1 stop
$317United Airlines
Sat, Jan 17 - Tue, Jan 20
United Airlines Logo
11:30 am - 10:52 pm
DSM
-
JAX
10h 22m2 stops
United Airlines Logo
4:23 pm - 9:50 pm
JAX
-
DSM
6h 27m1 stop
$322United Airlines
Sat, Jan 17 - Tue, Jan 20
United Airlines Logo
7:50 am - 8:10 pm
DSM
-
JAX
11h 20m2 stops
United Airlines Logo
1:45 pm - 9:50 pm
JAX
-
DSM
9h 05m2 stops
$327United Airlines
Sat, Jan 17 - Tue, Jan 20
Delta Logo
11:26 am - 6:52 pm
DSM
-
JAX
6h 26m1 stop
Delta Logo
6:30 am - 10:41 am
JAX
-
DSM
5h 11m1 stop
$335Delta
Tue, Feb 3 - Tue, Feb 10
Delta Logo
1:03 pm - 9:08 pm
DSM
-
JAX
7h 05m1 stop
Delta Logo
5:30 am - 10:38 am
JAX
-
DSM
6h 08m1 stop
$336Delta
Sat, Jan 10 - Tue, Jan 13

Delta flights from Des Moines to Jacksonville

Our best Delta deals on Des Moines to Jacksonville flight tickets
Delta
Jan 17
DSM6:54 amDes Moines
5h 39m
1 stop
JAX1:33 pmJacksonville
Jan 24
JAX3:15 pmJacksonville
7h 09m
1 stop
DSM9:24 pmDes Moines
$287
Find similar
Delta
Feb 3
DSM11:26 amDes Moines
6h 26m
1 stop
JAX6:52 pmJacksonville
Feb 10
JAX6:30 amJacksonville
5h 11m
1 stop
DSM10:41 amDes Moines
$335
Find similar
Delta
Jan 10
DSM6:54 amDes Moines
5h 39m
1 stop
JAX1:33 pmJacksonville
Jan 14
JAX1:16 pmJacksonville
4h 12m
1 stop
DSM4:28 pmDes Moines
$336
Find similar

American Airlines flights from Des Moines to Jacksonville

Our best American Airlines deals on Des Moines to Jacksonville flight tickets
American Airlines
Jan 17
DSM1:16 pmDes Moines
9h 10m
2 stops
JAX11:26 pmJacksonville
Jan 24
JAX11:53 amJacksonville
5h 31m
1 stop
DSM4:24 pmDes Moines
$292
Find similar
American Airlines
Jan 17
DSM6:00 amDes Moines
8h 41m
2 stops
JAX3:41 pmJacksonville
Jan 24
JAX6:00 amJacksonville
7h 46m
2 stops
DSM12:46 pmDes Moines
$297
Find similar
American Airlines
Jan 15
DSM4:25 pmDes Moines
4h 44m
1 stop
JAX10:09 pmJacksonville
Jan 18
JAX6:00 amJacksonville
7h 46m
2 stops
DSM12:46 pmDes Moines
$303
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Jacksonville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 21, 2025.
Use the filters below to find and compare flights from Des Moines to Jacksonville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

Sat 1/17

6:54 am-1:33 pm

1 stop5h 39m

Jacksonville

Sat 1/24

3:15 pm-9:24 pm

1 stop7h 09m

$287

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

Sat 1/17

1:16 pm-11:26 pm

2 stops9h 10m

Jacksonville

Sat 1/24

11:53 am-4:24 pm

1 stop5h 31m

$292

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

Sat 1/17

6:00 am-3:41 pm

2 stops8h 41m

Jacksonville

Sat 1/24

6:00 am-12:46 pm

2 stops7h 46m

$297

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

Thu 1/15

4:25 pm-10:09 pm

1 stop4h 44m

Jacksonville

Sun 1/18

6:00 am-12:46 pm

2 stops7h 46m

$303

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

Thu 1/15

6:00 am-1:49 pm

2 stops6h 49m

Jacksonville

Sun 1/18

6:00 am-12:46 pm

2 stops7h 46m

$308

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

Sat 1/17

3:04 pm-9:47 pm

1 stop5h 43m

Jacksonville

Tue 1/20

2:40 pm-9:50 pm

1 stop8h 10m

$317

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

Sat 1/17

11:30 am-10:52 pm

2 stops10h 22m

Jacksonville

Tue 1/20

4:23 pm-9:50 pm

1 stop6h 27m

$322

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

Sat 1/17

7:50 am-8:10 pm

2 stops11h 20m

Jacksonville

Tue 1/20

1:45 pm-9:50 pm

2 stops9h 05m

$327

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

Tue 2/3

11:26 am-6:52 pm

1 stop6h 26m

Jacksonville

Tue 2/10

6:30 am-10:41 am

1 stop5h 11m

$335

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

Sat 1/10

1:03 pm-9:08 pm

1 stop7h 05m

Jacksonville

Tue 1/13

5:30 am-10:38 am

1 stop6h 08m

$336

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
1
2

See travel insights to Jacksonville from

How to get the cheapest flight ticket from Des Moines to Jacksonville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Jacksonville?

If you are unable to visit Jacksonville during the month of October, then departing from Des Moines during the month August is also very affordable. Most momondo users find prices during this month for around $98.

What is the cheapest day to depart on your flight to Jacksonville?

According to our data, Thursday is the cheapest day to fly to Jacksonville from Des Moines. The lowest ticket price found for a Thursday departure recently was $93. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. On the other hand, Monday is the most expensive day to depart from Des Moines because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $513.

What is the cheapest time of day to depart on your flight to Jacksonville?

Flying to Jacksonville from Des Moines in the morning is the least expensive time of day to depart. momondo users have found prices as low as $93 when looking at flights departing in the morning. Flights to Jacksonville are more costly in the afternoon, with an average ticket price of $397. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Des Moines to Jacksonville flight route?

Fly from Des Moines to Jacksonville for the best Des Moines - Jacksonville flight prices

How far in advance should I book a flight to Jacksonville?

You are more likely to see cheaper flights to Jacksonville from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Jacksonville for around $262 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Jacksonville from Des Moines for as low as $103 on momondo.

What cabin class options are available on Des Moines to Jacksonville flights?

There is only 1 cabin class available to choose from on Des Moines to Jacksonville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Des Moines to Jacksonville flights?

No. A direct flight is the cheapest option for a flight between Des Moines to Jacksonville.

How have Des Moines to Jacksonville flight prices changed over time?

As of December 2025, prices for Des Moines to Jacksonville flights are approximately 8% more expensive when compared to flights at the same time last year.

When to book flights from Des Moines to Jacksonville

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Jacksonville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Jacksonville (DSM to JAX) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Jacksonville

Fastest flight time

4h 35m

Direct flights

None
The fastest flight from Des Moines to Jacksonville takes 4h 35m
There are no direct flights from Des Moines to Jacksonville. There are no popular flight routes from Des Moines to Jacksonville.
Search flight deals

  • How far is Des Moines to Jacksonville by plane?

    There are 1023.3 mi between Des Moines and Jacksonville. In terms of flight time, this usually takes a little over 4h 35m.

  • When did momondo last update prices for flights from Des Moines Airport to Jacksonville Airport?

    Prices for flights from Des Moines Airport to Jacksonville Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Jacksonville Airport?

  • How old do you have to be to fly from Des Moines Airport to Jacksonville Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Jacksonville Airport.

  • What documentation or ID do you need to fly to Jacksonville Airport?

    The travel and health documents required for your trip to Jacksonville Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Jacksonville Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Des Moines to Jacksonville?

  • What is the most popular airline from Des Moines to Jacksonville?

Best airlines flying from Des Moines to Jacksonville

Compare and see reviews for airlines that fly from Des Moines to Jacksonville with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $78Free CancellationRating
7.2
702 reviews
Search Allegiant Air flights
American AirlinesPriceFrom $216Free CancellationRating
7.2
11,051 reviews
Search American Airlines flights
DeltaPriceFrom $231Free CancellationRating
7.9
8,017 reviews
Search Delta flights
SouthwestPriceFrom $308Free CancellationRating
8.0
4,254 reviews
Search Southwest flights

Traveling to a place near Jacksonville?

Book flights to Jacksonville if you plan to visit one of these locations
Fernandina Beach
Jacksonville Beach
Orange Park
Ponte Vedra Beach
Kingsland
Waycross
Atlantic Beach
Neptune Beach
St Johns
Yulee
Cumberland Island

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Jacksonville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Des Moines to Jacksonville. momondo saves you time and could save you money on your trip.

Can I find flights from Des Moines to Jacksonville with flexible booking policies on momondo?

All flight searches from Des Moines to Jacksonville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Des Moines to Jacksonville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Des Moines to Jacksonville.

I’m not ready to book a flight from Des Moines to Jacksonville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Des Moines to Jacksonville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Jacksonville and let you know when they change.

An easier way to manage your Jacksonville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Tue 1/20
Tue 1/27
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States