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Cheap flights from Des Moines to Fort Myers from $159

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Fort Myers departing on 10/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Des Moines to Fort Myers

Cheap round-trip flights

Delta Logo
6:40 pm - 12:45 amDSM-RSW
5h 05m1 stop
Delta Logo
6:15 pm - 10:39 pmRSW-DSM
5h 24m1 stop
$317Delta
Find Deal
Tue, Aug 5 - Mon, Aug 11
American Airlines Logo
5:12 am - 5:38 pmDSM-RSW
11h 26m2 stops
American Airlines Logo
4:34 pm - 10:58 pmRSW-DSM
7h 24m1 stop
$322American Airlines
Find Deal
Tue, Aug 26 - Tue, Sep 2
American Airlines Logo
5:12 am - 1:42 pmDSM-RSW
7h 30m1 stop
American Airlines Logo
4:14 pm - 11:24 pmRSW-DSM
8h 10m2 stops
$323American Airlines
Find Deal
Thu, Aug 14 - Thu, Aug 21
 Logo
1:13 pm - 10:18 amDSM-RSW
20h 05m2 stops
 Logo
7:20 pm - 6:05 pmRSW-DSM
23h 45m2 stops
Sat, Jul 26 - Thu, Jul 31
American Airlines Logo
9:28 am - 10:27 pmDSM-RSW
11h 59m2 stops
American Airlines Logo
9:14 am - 7:20 pmRSW-DSM
11h 06m2 stops
$327American Airlines
Find Deal
Tue, Aug 26 - Tue, Sep 2
Delta Logo
5:59 pm - 12:45 amDSM-RSW
5h 46m1 stop
Delta Logo
6:40 am - 1:59 pmRSW-DSM
8h 19m1 stop
$337Delta
Find Deal
Sat, Aug 2 - Sun, Aug 10
United Airlines Logo
6:24 am - 3:02 pmDSM-RSW
7h 38m1 stop
United Airlines Logo
5:30 pm - 10:17 pmRSW-DSM
5h 47m1 stop
$397United Airlines
Find Deal
Tue, Aug 5 - Thu, Aug 7
United Airlines Logo
11:25 am - 8:32 pmDSM-RSW
8h 07m1 stop
United Airlines Logo
1:45 pm - 9:47 pmRSW-DSM
9h 02m2 stops
$402United Airlines
Find Deal
Tue, Aug 5 - Thu, Aug 7
Southwest Logo
6:50 pm - 12:20 amDSM-RSW
4h 30m1 stop
Southwest Logo
12:30 pm - 7:55 pmRSW-DSM
8h 25m1 stop
$416Southwest
Find Deal
Sun, Nov 30 - Mon, Dec 8
Southwest Logo
6:50 pm - 12:05 amDSM-RSW
4h 15m1 stop
Southwest Logo
12:15 pm - 11:35 pmRSW-DSM
12h 20m2 stops
$418Southwest
Find Deal
Mon, Dec 29 - Mon, Jan 5

Southwest flights from Des Moines to Fort Myers

Our best Southwest deals on Des Moines to Fort Myers flight tickets
Southwest
Nov 30
DSM6:50 pmDes Moines
4h 30m
1 stop
RSW12:20 amFort Myers SW Florida Intl
Dec 8
RSW12:30 pmFort Myers SW Florida Intl
8h 25m
1 stop
DSM7:55 pmDes Moines
Southwest
Dec 29
DSM6:50 pmDes Moines
4h 15m
1 stop
RSW12:05 amFort Myers SW Florida Intl
Jan 5
RSW12:15 pmFort Myers SW Florida Intl
12h 20m
2 stops
DSM11:35 pmDes Moines
Southwest
Jul 4
DSM8:35 amDes Moines
10h 10m
2 stops
RSW7:45 pmFort Myers SW Florida Intl
Jul 6
RSW7:20 amFort Myers SW Florida Intl
4h 55m
1 stop
DSM11:15 amDes Moines

American Airlines flights from Des Moines to Fort Myers

Our best American Airlines deals on Des Moines to Fort Myers flight tickets
American Airlines
Aug 26
DSM5:12 amDes Moines
11h 26m
2 stops
RSW5:38 pmFort Myers SW Florida Intl
Sep 2
RSW4:34 pmFort Myers SW Florida Intl
7h 24m
1 stop
DSM10:58 pmDes Moines
American Airlines
Aug 14
DSM5:12 amDes Moines
7h 30m
1 stop
RSW1:42 pmFort Myers SW Florida Intl
Aug 21
RSW4:14 pmFort Myers SW Florida Intl
8h 10m
2 stops
DSM11:24 pmDes Moines
American Airlines
Aug 26
DSM9:28 amDes Moines
11h 59m
2 stops
RSW10:27 pmFort Myers SW Florida Intl
Sep 2
RSW9:14 amFort Myers SW Florida Intl
11h 06m
2 stops
DSM7:20 pmDes Moines

See travel insights to Fort Myers from

How to get the cheapest flight ticket from Des Moines to Fort Myers

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Fort Myers?

In general, August is the cheapest month to fly from Des Moines to Fort Myers. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $316. If you are unable to visit Fort Myers during the month of August, then departing from Des Moines during the month September is also very affordable. Most momondo users find prices during this month for around $347.

What is the cheapest day to depart on your flight to Fort Myers?

The cheapest day to depart from Des Moines to Fort Myers is on a Tuesday when prices can be found for as low as $376. Flights from Des Moines to Fort Myers on a Sunday will generally be more expensive and average around $461. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Fort Myers?

The cheapest time of day to fly to Fort Myers is at noon when flights can be purchased for as low as $361. Flights in the morning are often more expensive with an average ticket price of $442.

How far in advance should I book a flight to Fort Myers?

You are more likely to see cheaper flights to Fort Myers from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Fort Myers for around $402 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Fort Myers from Des Moines for as low as $316 on momondo.

How have Des Moines to Fort Myers flight prices changed over time?

As of July 2025, prices for Des Moines to Fort Myers flights are approximately 12% cheaper when compared to flights at the same time last year.

When to book flights from Des Moines to Fort Myers

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Fort Myers according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Fort Myers (DSM to RSW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Fort Myers

Best Price Found

$159

Fastest flight time

4h 15m

Direct flights

None

Airports in Fort Myers

1 airport
The best one-way flight to Fort Myers from Des Moines in the past 72 hours is $159. The best round-trip flight deal from Des Moines to Fort Myers found on momondo in the last 72 hours is $317.
The fastest flight from Des Moines to Fort Myers takes 4h 15m
There are no direct flights from Des Moines to Fort Myers. Popular non-direct route for this connection is Des Moines Airport - Fort Myers SW Florida Intl Airport.
There is 1 airport near Fort Myers: Fort Myers SW Florida Intl (RSW)

  • How far is Des Moines to Fort Myers SW Florida Intl by plane?

    A flight from Des Moines to Fort Myers SW Florida Intl will travel around 1228.7 mi. A reasonable flight in good conditions will take 4h 15m.

  • When did momondo last update prices for flights from Des Moines Airport to Fort Myers SW Florida Intl Airport?

    Prices for flights from Des Moines Airport to Fort Myers SW Florida Intl Airport are updated daily.

  • How many operators does momondo search for flights from Des Moines Airport to Fort Myers SW Florida Intl Airport?

  • How old do you have to be to fly from Des Moines Airport to Fort Myers SW Florida Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Fort Myers SW Florida Intl Airport.

  • What documentation or ID do you need to fly to Fort Myers SW Florida Intl Airport?

    The necessary travel and health documents for your Fort Myers SW Florida Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Fort Myers?


Best airlines flying from Des Moines to Fort Myers

Compare and see reviews for airlines that fly from Des Moines to Fort Myers with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $107Free CancellationRating
7.2
709 reviews
Search Allegiant Air flights
United AirlinesPriceFrom $276Free CancellationRating
7.4
8,858 reviews
Search United Airlines flights
DeltaPriceFrom $284Free CancellationRating
8.0
7,975 reviews
Search Delta flights
American AirlinesPriceFrom $306Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
SouthwestPriceFrom $316Free CancellationRating
8.0
4,272 reviews
Search Southwest flights

Traveling to a place near Fort Myers?

Book flights to Fort Myers if you plan to visit one of these locations
Sanibel
Fort Myers Beach
Cape Coral
Captiva
Estero
North Fort Myers
Boca Grande
Lehigh Acres

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Fort Myers?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Fort Myers from Des Moines.

Can I find flights from Des Moines to Fort Myers with flexible booking policies on momondo?

momondo does allow users to show only those flights to Fort Myers from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Fort Myers?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Fort Myers from Des Moines.

I’m not ready to book a flight from Des Moines to Fort Myers right now. Can momondo alert me if prices change?

Price alerts on flights to Fort Myers from Des Moines are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.


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