Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Des Moines to Fort Myers from $61

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Fort Myers departing on 1/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Des Moines to Fort Myers

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
1:56 pm - 6:00 pmDSM-RSW
3h 04mnonstop
Allegiant Air Logo
6:54 pm - 9:13 pmRSW-DSM
3h 19mnonstop
$118Allegiant Air
Find Deal
Fri, Dec 5 - Mon, Dec 8
Allegiant Air Logo
2:08 pm - 6:12 pmDSM-RSW
3h 04mnonstop
Allegiant Air Logo
7:02 pm - 9:21 pmRSW-DSM
3h 19mnonstop
$176Allegiant Air
Find Deal
Fri, Jan 16 - Mon, Jan 19
Delta Logo
5:34 am - 12:32 pmDSM-RSW
5h 58m1 stop
Delta Logo
7:15 am - 2:19 pmRSW-DSM
8h 04m1 stop
$237Delta
Find Deal
Tue, Dec 9 - Tue, Dec 16
American Airlines Logo
1:17 pm - 11:29 pmDSM-RSW
9h 12m2 stops
American Airlines Logo
6:10 am - 11:42 amRSW-DSM
6h 32m1 stop
$242American Airlines
Find Deal
Tue, Dec 9 - Tue, Dec 16
Delta Logo
1:03 pm - 9:38 pmDSM-RSW
7h 35m1 stop
Delta Logo
11:18 am - 7:34 pmRSW-DSM
9h 16m1 stop
$249Delta
Find Deal
Sat, Jan 17 - Thu, Jan 22
Allegiant Air Logo
2:08 pm - 6:12 pmDSM-RSW
3h 04mnonstop
Allegiant Air Logo
7:02 pm - 9:21 pmRSW-DSM
3h 19mnonstop
$252Allegiant Air
Find Deal
Fri, Feb 6 - Mon, Feb 9
American Airlines Logo
1:16 pm - 11:58 pmDSM-RSW
9h 42m2 stops
American Airlines Logo
8:36 am - 3:15 pmRSW-DSM
7h 39m1 stop
$254American Airlines
Find Deal
Sat, Jan 17 - Thu, Jan 22
Southwest Logo
6:15 am - 5:00 pmDSM-RSW
9h 45m2 stops
Southwest Logo
12:30 pm - 9:35 pmRSW-DSM
10h 05m2 stops
$381Southwest
Find Deal
Tue, Dec 9 - Tue, Dec 16
United Airlines Logo
5:45 am - 3:27 pmDSM-RSW
8h 42m1 stop
United Airlines Logo
9:20 am - 2:20 pmRSW-DSM
6h 00m1 stop
$427United Airlines
Find Deal
Tue, Dec 9 - Mon, Dec 15
United Airlines Logo
8:00 am - 9:41 pmDSM-RSW
12h 41m2 stops
United Airlines Logo
3:55 pm - 11:44 pmRSW-DSM
8h 49m1 stop
$432United Airlines
Find Deal
Tue, Dec 9 - Mon, Dec 15

Allegiant Air flights from Des Moines to Fort Myers

Our best Allegiant Air deals on Des Moines to Fort Myers flight tickets
Allegiant Air
Dec 5
DSM1:56 pmDes Moines
3h 04m
RSW6:00 pmFort Myers SW Florida Intl
Dec 8
RSW6:54 pmFort Myers SW Florida Intl
3h 19m
DSM9:13 pmDes Moines
$118
Find similar
Allegiant Air
Jan 16
DSM2:08 pmDes Moines
3h 04m
RSW6:12 pmFort Myers SW Florida Intl
Jan 19
RSW7:02 pmFort Myers SW Florida Intl
3h 19m
DSM9:21 pmDes Moines
$176
Find similar
Allegiant Air
Feb 6
DSM2:08 pmDes Moines
3h 04m
RSW6:12 pmFort Myers SW Florida Intl
Feb 9
RSW7:02 pmFort Myers SW Florida Intl
3h 19m
DSM9:21 pmDes Moines
$252
Find similar

Delta flights from Des Moines to Fort Myers

Our best Delta deals on Des Moines to Fort Myers flight tickets
Delta
Dec 9
DSM5:34 amDes Moines
5h 58m
1 stop
RSW12:32 pmFort Myers SW Florida Intl
Dec 16
RSW7:15 amFort Myers SW Florida Intl
8h 04m
1 stop
DSM2:19 pmDes Moines
$237
Find similar
Delta
Jan 17
DSM1:03 pmDes Moines
7h 35m
1 stop
RSW9:38 pmFort Myers SW Florida Intl
Jan 22
RSW11:18 amFort Myers SW Florida Intl
9h 16m
1 stop
DSM7:34 pmDes Moines
$249
Find similar
Delta
Jan 8
DSM7:34 amDes Moines
9h 58m
1 stop
RSW6:32 pmFort Myers SW Florida Intl
Jan 14
RSW5:35 amFort Myers SW Florida Intl
6h 06m
1 stop
DSM10:41 amDes Moines
$310
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Fort Myers that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 10, 2025.
Use the filters below to find and compare flights from Des Moines to Fort Myers that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Fri 12/5

1:56 pm-6:00 pm

Nonstop3h 04m

Fort Myers SW Florida Intl

Mon 12/8

6:54 pm-9:13 pm

Nonstop3h 19m

$118

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Fri 1/16

2:08 pm-6:12 pm

Nonstop3h 04m

Fort Myers SW Florida Intl

Mon 1/19

7:02 pm-9:21 pm

Nonstop3h 19m

$176

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Tue 12/9

5:34 am-12:32 pm

1 stop5h 58m

Fort Myers SW Florida Intl

Tue 12/16

7:15 am-2:19 pm

1 stop8h 04m

$237

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Tue 12/9

1:17 pm-11:29 pm

2 stops9h 12m

Fort Myers SW Florida Intl

Tue 12/16

6:10 am-11:42 am

1 stop6h 32m

$242

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Sat 1/17

1:03 pm-9:38 pm

1 stop7h 35m

Fort Myers SW Florida Intl

Thu 1/22

11:18 am-7:34 pm

1 stop9h 16m

$249

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Fri 2/6

2:08 pm-6:12 pm

Nonstop3h 04m

Fort Myers SW Florida Intl

Mon 2/9

7:02 pm-9:21 pm

Nonstop3h 19m

$252

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Sat 1/17

1:16 pm-11:58 pm

2 stops9h 42m

Fort Myers SW Florida Intl

Thu 1/22

8:36 am-3:15 pm

1 stop7h 39m

$254

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Tue 12/9

6:15 am-5:00 pm

2 stops9h 45m

Fort Myers SW Florida Intl

Tue 12/16

12:30 pm-9:35 pm

2 stops10h 05m

$381

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Tue 12/9

5:45 am-3:27 pm

1 stop8h 42m

Fort Myers SW Florida Intl

Mon 12/15

9:20 am-2:20 pm

1 stop6h 00m

$427

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Tue 12/9

8:00 am-9:41 pm

2 stops12h 41m

Fort Myers SW Florida Intl

Mon 12/15

3:55 pm-11:44 pm

1 stop8h 49m

$432

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Fort Myers from

How to get the cheapest flight ticket from Des Moines to Fort Myers

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Fort Myers?

In general, October is the cheapest month to fly from Des Moines to Fort Myers. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $314. If you are unable to visit Fort Myers during the month of October, then departing from Des Moines during the month August is also very affordable. Most momondo users find prices during this month for around $316.

What is the cheapest day to depart on your flight to Fort Myers?

The cheapest day to depart from Des Moines to Fort Myers is on a Monday when prices can be found for as low as $264. Flights from Des Moines to Fort Myers on a Thursday will generally be more expensive and average around $406. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Fort Myers?

The cheapest time of day to fly to Fort Myers is at noon when flights can be purchased for as low as $265. Flights in the afternoon are often more expensive with an average ticket price of $386.

What is the cheapest Des Moines to Fort Myers SW Florida Intl flight route?

Fly from Des Moines to Fort Myers SW Florida Intl for the best Des Moines - Fort Myers SW Florida Intl flight prices

How far in advance should I book a flight to Fort Myers?

You are more likely to see cheaper flights to Fort Myers from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Fort Myers for around $385 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Fort Myers from Des Moines for as low as $321 on momondo.

What cabin class options are available on Des Moines to Fort Myers SW Florida Intl flights?

There is only 1 cabin class available to choose from on Des Moines to Fort Myers SW Florida Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Des Moines to Fort Myers flights?

No. A direct flight is the cheapest option for a flight between Des Moines to Fort Myers.

How have Des Moines to Fort Myers flight prices changed over time?

As of November 2025, prices for Des Moines to Fort Myers flights are approximately 11% cheaper when compared to flights at the same time last year.

When to book flights from Des Moines to Fort Myers

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Fort Myers according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Fort Myers (DSM to RSW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Fort Myers

Best Price Found

$230

Fastest flight time

3h 04m

Direct flights

Tue, Thu and Sat

Airports in Fort Myers

1 airport
The best one-way flight to Fort Myers from Des Moines in the past 72 hours is $230. The best round-trip flight deal from Des Moines to Fort Myers found on momondo in the last 72 hours is $175.
The fastest flight from Des Moines to Fort Myers takes 3h 04m
Direct flights go from Des Moines to Fort Myers on Tuesday, Thursday and Saturday. The only airline offering direct flights is Allegiant Air.
There is 1 airport near Fort Myers: Fort Myers SW Florida Intl (RSW)
Search flight deals

  • How far is Des Moines to Fort Myers SW Florida Intl by plane?

    A flight from Des Moines to Fort Myers SW Florida Intl will travel around 1228.7 mi. A reasonable flight in good conditions will take 3h 04m.

  • When did momondo last update prices for flights from Des Moines Airport to Fort Myers SW Florida Intl Airport?

    Prices for flights from Des Moines Airport to Fort Myers SW Florida Intl Airport are updated daily.

  • How many operators does momondo search for flights from Des Moines Airport to Fort Myers SW Florida Intl Airport?

  • How old do you have to be to fly from Des Moines Airport to Fort Myers SW Florida Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Fort Myers SW Florida Intl Airport.

  • What documentation or ID do you need to fly to Fort Myers SW Florida Intl Airport?

    The necessary travel and health documents for your Fort Myers SW Florida Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Des Moines to Fort Myers?

  • What is the most popular airline from Des Moines to Fort Myers?

Best airlines flying from Des Moines to Fort Myers

Compare and see reviews for airlines that fly from Des Moines to Fort Myers with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $142Free CancellationRating
7.2
697 reviews
Search Allegiant Air flights
United AirlinesPriceFrom $260Free CancellationRating
7.4
9,012 reviews
Search United Airlines flights
DeltaPriceFrom $263Free CancellationRating
7.9
8,007 reviews
Search Delta flights
American AirlinesPriceFrom $276Free CancellationRating
7.2
11,045 reviews
Search American Airlines flights
SouthwestPriceFrom $301Free CancellationRating
8.0
4,235 reviews
Search Southwest flights

Traveling to a place near Fort Myers?

Book flights to Fort Myers if you plan to visit one of these locations
Fort Myers Beach
Sanibel
Cape Coral
Captiva
Estero
North Fort Myers
Boca Grande
Lehigh Acres

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Fort Myers?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Fort Myers from Des Moines.

Can I find flights from Des Moines to Fort Myers with flexible booking policies on momondo?

momondo does allow users to show only those flights to Fort Myers from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Fort Myers?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Fort Myers from Des Moines.

I’m not ready to book a flight from Des Moines to Fort Myers right now. Can momondo alert me if prices change?

Price alerts on flights to Fort Myers from Des Moines are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Fort Myers trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 12/10
Wed 12/17
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States