Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Des Moines to Fort Myers from $42

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Fort Myers departing on 1/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Des Moines to Fort Myers

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
2:08 pm - 6:12 pmDSM-RSW
3h 04mnonstop
Allegiant Air Logo
7:02 pm - 9:21 pmRSW-DSM
3h 19mnonstop
$96Allegiant Air
Find Deal
Mon, Jan 12 - Fri, Jan 16
Allegiant Air Logo
1:56 pm - 6:00 pmDSM-RSW
3h 04mnonstop
Allegiant Air Logo
6:50 pm - 9:09 pmRSW-DSM
3h 19mnonstop
$166Allegiant Air
Find Deal
Fri, Nov 21 - Mon, Nov 24
American Airlines Logo
4:00 pm - 10:50 pmDSM-RSW
5h 50m1 stop
American Airlines Logo
3:04 pm - 10:11 pmRSW-DSM
8h 07m1 stop
$249American Airlines
Find Deal
Sun, Jan 11 - Sat, Jan 17
American Airlines Logo
4:00 pm - 10:50 pmDSM-RSW
5h 50m1 stop
American Airlines Logo
1:12 pm - 10:11 pmRSW-DSM
9h 59m2 stops
$254American Airlines
Find Deal
Sun, Jan 11 - Sat, Jan 17
Delta Logo
4:59 pm - 11:50 pmDSM-RSW
5h 51m1 stop
Delta Logo
7:15 am - 2:26 pmRSW-DSM
8h 11m1 stop
$297Delta
Find Deal
Mon, Dec 1 - Sat, Dec 6
Southwest Logo
4:15 pm - 9:45 pmDSM-RSW
4h 30m1 stop
Southwest Logo
6:15 pm - 11:55 pmRSW-DSM
6h 40m1 stop
$322Southwest
Find Deal
Wed, Dec 10 - Sat, Dec 20
Southwest Logo
8:35 am - 5:00 pmDSM-RSW
7h 25m1 stop
Southwest Logo
6:35 am - 10:50 amRSW-DSM
5h 15m1 stop
$323Southwest
Find Deal
Thu, Jan 29 - Thu, Feb 5
Delta Logo
5:16 pm - 11:03 pmDSM-RSW
4h 47m1 stop
Delta Logo
6:02 pm - 10:31 pmRSW-DSM
5h 29m1 stop
$361Delta
Find Deal
Thu, Jan 22 - Sat, Jan 31
United Airlines Logo
11:26 am - 11:38 pmDSM-RSW
11h 12m2 stops
United Airlines Logo
7:00 am - 4:12 pmRSW-DSM
10h 12m2 stops
$382United Airlines
Find Deal
Mon, Dec 1 - Sat, Dec 6
United Airlines Logo
8:08 am - 3:43 pmDSM-RSW
6h 35m1 stop
United Airlines Logo
4:57 pm - 10:20 pmRSW-DSM
6h 23m1 stop
$394United Airlines
Find Deal
Thu, Feb 12 - Tue, Feb 17

Southwest flights from Des Moines to Fort Myers

Our best Southwest deals on Des Moines to Fort Myers flight tickets
Southwest
Dec 10
DSM4:15 pmDes Moines
4h 30m
1 stop
RSW9:45 pmFort Myers SW Florida Intl
Dec 20
RSW6:15 pmFort Myers SW Florida Intl
6h 40m
1 stop
DSM11:55 pmDes Moines
$322
Find similar
Southwest
Jan 29
DSM8:35 amDes Moines
7h 25m
1 stop
RSW5:00 pmFort Myers SW Florida Intl
Feb 5
RSW6:35 amFort Myers SW Florida Intl
5h 15m
1 stop
DSM10:50 amDes Moines
$323
Find similar
Southwest
Jan 29
DSM8:35 amDes Moines
11h 25m
2 stops
RSW9:00 pmFort Myers SW Florida Intl
Feb 5
RSW6:35 amFort Myers SW Florida Intl
5h 15m
1 stop
DSM10:50 amDes Moines
$328
Find similar

United Airlines flights from Des Moines to Fort Myers

Our best United Airlines deals on Des Moines to Fort Myers flight tickets
United Airlines
Dec 1
DSM11:26 amDes Moines
11h 12m
2 stops
RSW11:38 pmFort Myers SW Florida Intl
Dec 6
RSW7:00 amFort Myers SW Florida Intl
10h 12m
2 stops
DSM4:12 pmDes Moines
$382
Find similar
United Airlines
Feb 12
DSM8:08 amDes Moines
6h 35m
1 stop
RSW3:43 pmFort Myers SW Florida Intl
Feb 17
RSW4:57 pmFort Myers SW Florida Intl
6h 23m
1 stop
DSM10:20 pmDes Moines
$394
Find similar
United Airlines
Mar 2
DSM8:00 amDes Moines
11h 09m
2 stops
RSW8:09 pmFort Myers SW Florida Intl
Mar 8
RSW4:45 pmFort Myers SW Florida Intl
6h 51m
1 stop
DSM10:36 pmDes Moines
$401
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Fort Myers that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Des Moines to Fort Myers that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Mon 1/12

2:08 pm-6:12 pm

Nonstop3h 04m

Fort Myers SW Florida Intl

Fri 1/16

7:02 pm-9:21 pm

Nonstop3h 19m

$96

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Fri 11/21

1:56 pm-6:00 pm

Nonstop3h 04m

Fort Myers SW Florida Intl

Mon 11/24

6:50 pm-9:09 pm

Nonstop3h 19m

$166

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Sun 1/11

4:00 pm-10:50 pm

1 stop5h 50m

Fort Myers SW Florida Intl

Sat 1/17

3:04 pm-10:11 pm

1 stop8h 07m

$249

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Sun 1/11

4:00 pm-10:50 pm

1 stop5h 50m

Fort Myers SW Florida Intl

Sat 1/17

1:12 pm-10:11 pm

2 stops9h 59m

$254

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Mon 12/1

4:59 pm-11:50 pm

1 stop5h 51m

Fort Myers SW Florida Intl

Sat 12/6

7:15 am-2:26 pm

1 stop8h 11m

$297

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Wed 12/10

4:15 pm-9:45 pm

1 stop4h 30m

Fort Myers SW Florida Intl

Sat 12/20

6:15 pm-11:55 pm

1 stop6h 40m

$322

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Thu 1/29

8:35 am-5:00 pm

1 stop7h 25m

Fort Myers SW Florida Intl

Thu 2/5

6:35 am-10:50 am

1 stop5h 15m

$323

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Thu 1/22

5:16 pm-11:03 pm

1 stop4h 47m

Fort Myers SW Florida Intl

Sat 1/31

6:02 pm-10:31 pm

1 stop5h 29m

$361

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Mon 12/1

11:26 am-11:38 pm

2 stops11h 12m

Fort Myers SW Florida Intl

Sat 12/6

7:00 am-4:12 pm

2 stops10h 12m

$382

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Thu 2/12

8:08 am-3:43 pm

1 stop6h 35m

Fort Myers SW Florida Intl

Tue 2/17

4:57 pm-10:20 pm

1 stop6h 23m

$394

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Fort Myers from

How to get the cheapest flight ticket from Des Moines to Fort Myers

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Des Moines and Fort Myers?

What is the cheapest month to fly to Fort Myers?

In general, August is the cheapest month to fly from Des Moines to Fort Myers. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $316. If you are unable to visit Fort Myers during the month of August, then departing from Des Moines during the month September is also very affordable. Most momondo users find prices during this month for around $316.

What is the cheapest day to depart on your flight to Fort Myers?

The cheapest day to depart from Des Moines to Fort Myers is on a Friday when prices can be found for as low as $282. Flights from Des Moines to Fort Myers on a Thursday will generally be more expensive and average around $406. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Fort Myers?

The cheapest time of day to fly to Fort Myers is at noon when flights can be purchased for as low as $265. Flights in the afternoon are often more expensive with an average ticket price of $386.

What is the cheapest Des Moines to Fort Myers SW Florida Intl flight route?

Fly from Des Moines to Fort Myers SW Florida Intl for the best Des Moines - Fort Myers SW Florida Intl flight prices

How far in advance should I book a flight to Fort Myers?

You are more likely to see cheaper flights to Fort Myers from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Fort Myers for around $384 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Fort Myers from Des Moines for as low as $303 on momondo.

What cabin class options are available on Des Moines to Fort Myers SW Florida Intl flights?

There is only 1 cabin class available to choose from on Des Moines to Fort Myers SW Florida Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Des Moines to Fort Myers flights?

No. A direct flight is the cheapest option for a flight between Des Moines to Fort Myers.

How have Des Moines to Fort Myers flight prices changed over time?

As of November 2025, prices for Des Moines to Fort Myers flights are approximately 9% cheaper when compared to flights at the same time last year.

When to book flights from Des Moines to Fort Myers

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Fort Myers according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Fort Myers (DSM to RSW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Fort Myers

Best Price Found

$230

Fastest flight time

3h 04m

Direct flights

Tue and Sat

Airports in Fort Myers

1 airport
The best one-way flight to Fort Myers from Des Moines in the past 72 hours is $230. The best round-trip flight deal from Des Moines to Fort Myers found on momondo in the last 72 hours is $175.
The fastest flight from Des Moines to Fort Myers takes 3h 04m
Direct flights go from Des Moines to Fort Myers on Tuesday and Saturday. The only airline offering direct flights is Allegiant Air.
There is 1 airport near Fort Myers: Fort Myers SW Florida Intl (RSW)
Search flight deals

  • How far is Des Moines to Fort Myers SW Florida Intl by plane?

    A flight from Des Moines to Fort Myers SW Florida Intl will travel around 1228.7 mi. A reasonable flight in good conditions will take 3h 04m.

  • When did momondo last update prices for flights from Des Moines Airport to Fort Myers SW Florida Intl Airport?

    Prices for flights from Des Moines Airport to Fort Myers SW Florida Intl Airport are updated daily.

  • How many operators does momondo search for flights from Des Moines Airport to Fort Myers SW Florida Intl Airport?

  • How old do you have to be to fly from Des Moines Airport to Fort Myers SW Florida Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Fort Myers SW Florida Intl Airport.

  • What documentation or ID do you need to fly to Fort Myers SW Florida Intl Airport?

    The necessary travel and health documents for your Fort Myers SW Florida Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Des Moines to Fort Myers?

  • What is the most popular airline from Des Moines to Fort Myers?

Best airlines flying from Des Moines to Fort Myers

Compare and see reviews for airlines that fly from Des Moines to Fort Myers with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $142Free CancellationRating
7.2
694 reviews
Search Allegiant Air flights
United AirlinesPriceFrom $260Free CancellationRating
7.4
8,997 reviews
Search United Airlines flights
DeltaPriceFrom $263Free CancellationRating
7.9
8,002 reviews
Search Delta flights
American AirlinesPriceFrom $276Free CancellationRating
7.2
11,038 reviews
Search American Airlines flights
SouthwestPriceFrom $301Free CancellationRating
8.0
4,238 reviews
Search Southwest flights

Traveling to a place near Fort Myers?

Book flights to Fort Myers if you plan to visit one of these locations
Fort Myers Beach
Sanibel
Cape Coral
Captiva
Estero
North Fort Myers
Boca Grande
Lehigh Acres

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Fort Myers?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Fort Myers from Des Moines.

Can I find flights from Des Moines to Fort Myers with flexible booking policies on momondo?

momondo does allow users to show only those flights to Fort Myers from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Fort Myers?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Fort Myers from Des Moines.

I’m not ready to book a flight from Des Moines to Fort Myers right now. Can momondo alert me if prices change?

Price alerts on flights to Fort Myers from Des Moines are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Fort Myers trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 12/3
Wed 12/10
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States