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Cheap flights from Des Moines to Fort Myers from $164

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Fort Myers departing on 12/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Des Moines to Fort Myers

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
1:56 pm - 6:00 pmDSM-RSW
3h 04mnonstop
Allegiant Air Logo
6:50 pm - 9:09 pmRSW-DSM
3h 19mnonstop
$178Allegiant Air
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Fri, Nov 21 - Mon, Nov 24
Delta Logo
2:45 pm - 11:50 pmDSM-RSW
8h 05m1 stop
Delta Logo
1:37 pm - 5:47 pmRSW-DSM
5h 10m1 stop
$237Delta
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Tue, Nov 18 - Tue, Dec 16
American Airlines Logo
2:19 pm - 11:29 pmDSM-RSW
8h 10m2 stops
American Airlines Logo
7:16 am - 2:33 pmRSW-DSM
8h 17m1 stop
$242American Airlines
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Tue, Nov 18 - Tue, Dec 16
Multiple Airlines Logo
1:56 pm - 6:00 pmDSM-RSW
3h 04mnonstop
Multiple Airlines Logo
5:45 pm - 7:01 pmRSW-DSM
26h 16m1 stop
$259Multiple Airlines
Find Deal
Fri, Nov 21 - Mon, Nov 24
American Airlines Logo
7:40 am - 2:17 pmDSM-RSW
5h 37m1 stop
American Airlines Logo
8:10 am - 1:16 pmRSW-DSM
6h 06m1 stop
$261American Airlines
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Mon, Feb 2 - Fri, Feb 13
Multiple Airlines Logo
5:21 pm - 9:56 pmDSM-RSW
27h 35m2 stops
Multiple Airlines Logo
6:50 pm - 9:09 pmRSW-DSM
3h 19mnonstop
$287Multiple Airlines
Find Deal
Wed, Nov 19 - Fri, Nov 21
Southwest Logo
5:45 am - 4:50 pmDSM-RSW
10h 05m2 stops
Southwest Logo
7:25 am - 2:55 pmRSW-DSM
8h 30m2 stops
$347Southwest
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Sat, Jan 10 - Sat, Jan 24
United Airlines Logo
3:15 pm - 10:17 pmDSM-RSW
6h 02m1 stop
United Airlines Logo
4:30 pm - 9:36 pmRSW-DSM
6h 06m1 stop
$407United Airlines
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Fri, Apr 17 - Mon, Apr 20
Southwest Logo
6:15 am - 5:10 pmDSM-RSW
9h 55m2 stops
Southwest Logo
12:30 pm - 9:35 pmRSW-DSM
10h 05m2 stops
$409Southwest
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Tue, Nov 18 - Tue, Dec 16
United Airlines Logo
9:09 am - 9:54 pmDSM-RSW
11h 45m2 stops
United Airlines Logo
9:24 am - 2:11 pmRSW-DSM
5h 47m1 stop
$412United Airlines
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Fri, Apr 17 - Mon, Apr 20

United Airlines flights from Des Moines to Fort Myers

Our best United Airlines deals on Des Moines to Fort Myers flight tickets
United Airlines
Apr 17
DSM3:15 pmDes Moines
6h 02m
1 stop
RSW10:17 pmFort Myers SW Florida Intl
Apr 20
RSW4:30 pmFort Myers SW Florida Intl
6h 06m
1 stop
DSM9:36 pmDes Moines
$407
Find similar
United Airlines
Apr 17
DSM9:09 amDes Moines
11h 45m
2 stops
RSW9:54 pmFort Myers SW Florida Intl
Apr 20
RSW9:24 amFort Myers SW Florida Intl
5h 47m
1 stop
DSM2:11 pmDes Moines
$412
Find similar
United Airlines
Nov 10
DSM9:01 amDes Moines
10h 15m
2 stops
RSW8:16 pmFort Myers SW Florida Intl
Nov 14
RSW5:08 pmFort Myers SW Florida Intl
6h 12m
1 stop
DSM10:20 pmDes Moines
$472
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Delta flights from Des Moines to Fort Myers

Our best Delta deals on Des Moines to Fort Myers flight tickets
Delta
Nov 18
DSM2:45 pmDes Moines
8h 05m
1 stop
RSW11:50 pmFort Myers SW Florida Intl
Dec 16
RSW1:37 pmFort Myers SW Florida Intl
5h 10m
1 stop
DSM5:47 pmDes Moines
$237
Find similar
Delta
Dec 18
DSM6:33 pmDes Moines
5h 05m
1 stop
RSW12:38 amFort Myers SW Florida Intl
Dec 22
RSW6:48 amFort Myers SW Florida Intl
4h 50m
1 stop
DSM10:38 amDes Moines
$327
Find similar
Delta
Nov 19
DSM7:48 amDes Moines
9h 46m
1 stop
RSW6:34 pmFort Myers SW Florida Intl
Nov 21
RSW4:12 pmFort Myers SW Florida Intl
7h 21m
1 stop
DSM10:33 pmDes Moines
$332
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momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Fort Myers that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from Des Moines to Fort Myers that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Fri 11/21

1:56 pm-6:00 pm

Nonstop3h 04m

Fort Myers SW Florida Intl

Mon 11/24

6:50 pm-9:09 pm

Nonstop3h 19m

$178

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Tue 11/18

2:45 pm-11:50 pm

1 stop8h 05m

Fort Myers SW Florida Intl

Tue 12/16

1:37 pm-5:47 pm

1 stop5h 10m

$237

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Tue 11/18

2:19 pm-11:29 pm

2 stops8h 10m

Fort Myers SW Florida Intl

Tue 12/16

7:16 am-2:33 pm

1 stop8h 17m

$242

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Fri 11/21

1:56 pm-6:00 pm

Nonstop3h 04m

Fort Myers SW Florida Intl

Mon 11/24

5:45 pm-7:01 pm

1 stop26h 16m

$259

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Mon 2/2

7:40 am-2:17 pm

1 stop5h 37m

Fort Myers SW Florida Intl

Fri 2/13

8:10 am-1:16 pm

1 stop6h 06m

$261

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Wed 11/19

5:21 pm-9:56 pm

2 stops27h 35m

Fort Myers SW Florida Intl

Fri 11/21

6:50 pm-9:09 pm

Nonstop3h 19m

$287

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Sat 1/10

5:45 am-4:50 pm

2 stops10h 05m

Fort Myers SW Florida Intl

Sat 1/24

7:25 am-2:55 pm

2 stops8h 30m

$347

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Fri 4/17

3:15 pm-10:17 pm

1 stop6h 02m

Fort Myers SW Florida Intl

Mon 4/20

4:30 pm-9:36 pm

1 stop6h 06m

$407

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Tue 11/18

6:15 am-5:10 pm

2 stops9h 55m

Fort Myers SW Florida Intl

Tue 12/16

12:30 pm-9:35 pm

2 stops10h 05m

$409

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Fri 4/17

9:09 am-9:54 pm

2 stops11h 45m

Fort Myers SW Florida Intl

Mon 4/20

9:24 am-2:11 pm

1 stop5h 47m

$412

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Fort Myers from

How to get the cheapest flight ticket from Des Moines to Fort Myers

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Fort Myers?

In general, August is the cheapest month to fly from Des Moines to Fort Myers. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $316. If you are unable to visit Fort Myers during the month of August, then departing from Des Moines during the month September is also very affordable. Most momondo users find prices during this month for around $316.

What is the cheapest day to depart on your flight to Fort Myers?

The cheapest day to depart from Des Moines to Fort Myers is on a Friday when prices can be found for as low as $282. Flights from Des Moines to Fort Myers on a Thursday will generally be more expensive and average around $406. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Fort Myers?

The cheapest time of day to fly to Fort Myers is at noon when flights can be purchased for as low as $265. Flights in the afternoon are often more expensive with an average ticket price of $386.

What is the cheapest Des Moines to Fort Myers SW Florida Intl flight route?

Fly from Des Moines to Fort Myers SW Florida Intl for the best Des Moines - Fort Myers SW Florida Intl flight prices

How far in advance should I book a flight to Fort Myers?

You are more likely to see cheaper flights to Fort Myers from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Fort Myers for around $385 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Fort Myers from Des Moines for as low as $303 on momondo.

What cabin class options are available on Des Moines to Fort Myers SW Florida Intl flights?

There is only 1 cabin class available to choose from on Des Moines to Fort Myers SW Florida Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Des Moines to Fort Myers flights?

No. A direct flight is the cheapest option for a flight between Des Moines to Fort Myers.

How have Des Moines to Fort Myers flight prices changed over time?

As of October 2025, prices for Des Moines to Fort Myers flights are approximately 15% cheaper when compared to flights at the same time last year.

When to book flights from Des Moines to Fort Myers

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Fort Myers according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Fort Myers (DSM to RSW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Fort Myers

Best Price Found

$173

Fastest flight time

3h 04m

Direct flights

Tue, Thu and Sat

Airports in Fort Myers

1 airport
The best flight deal from Des Moines to Fort Myers found on momondo in the last 72 hours is $173
The fastest flight from Des Moines to Fort Myers takes 3h 04m
Direct flights go from Des Moines to Fort Myers on Tuesday, Thursday and Saturday. The only airline offering direct flights is Allegiant Air.
There is 1 airport near Fort Myers: Fort Myers SW Florida Intl (RSW)
Search flight deals

  • How far is Des Moines to Fort Myers SW Florida Intl by plane?

    A flight from Des Moines to Fort Myers SW Florida Intl will travel around 1228.7 mi. A reasonable flight in good conditions will take 3h 04m.

  • When did momondo last update prices for flights from Des Moines Airport to Fort Myers SW Florida Intl Airport?

    Prices for flights from Des Moines Airport to Fort Myers SW Florida Intl Airport are updated daily.

  • How many operators does momondo search for flights from Des Moines Airport to Fort Myers SW Florida Intl Airport?

  • How old do you have to be to fly from Des Moines Airport to Fort Myers SW Florida Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Fort Myers SW Florida Intl Airport.

  • What documentation or ID do you need to fly to Fort Myers SW Florida Intl Airport?

    The necessary travel and health documents for your Fort Myers SW Florida Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Des Moines to Fort Myers?

  • What is the most popular airline from Des Moines to Fort Myers?

Best airlines flying from Des Moines to Fort Myers

Compare and see reviews for airlines that fly from Des Moines to Fort Myers with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $142Free CancellationRating
7.2
695 reviews
Search Allegiant Air flights
United AirlinesPriceFrom $260Free CancellationRating
7.4
8,996 reviews
Search United Airlines flights
DeltaPriceFrom $263Free CancellationRating
7.9
7,995 reviews
Search Delta flights
American AirlinesPriceFrom $276Free CancellationRating
7.2
11,033 reviews
Search American Airlines flights
SouthwestPriceFrom $310Free CancellationRating
8.0
4,235 reviews
Search Southwest flights

Traveling to a place near Fort Myers?

Book flights to Fort Myers if you plan to visit one of these locations
Fort Myers Beach
Sanibel
Cape Coral
Captiva
Estero
North Fort Myers
Boca Grande
Lehigh Acres

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Fort Myers?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Fort Myers from Des Moines.

Can I find flights from Des Moines to Fort Myers with flexible booking policies on momondo?

momondo does allow users to show only those flights to Fort Myers from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Fort Myers?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Fort Myers from Des Moines.

I’m not ready to book a flight from Des Moines to Fort Myers right now. Can momondo alert me if prices change?

Price alerts on flights to Fort Myers from Des Moines are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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