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Cheap flights from Des Moines to Fort Myers from $129

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Fort Myers departing on 11/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Des Moines to Fort Myers

Cheap round-trip flights

Allegiant Air Logo
1:56 pm - 6:00 pmDSM-RSW
3h 04mnonstop
Allegiant Air Logo
6:50 pm - 9:09 pmRSW-DSM
3h 19mnonstop
$161Allegiant Air
Find Deal
Sun, Nov 30 - Fri, Dec 5
Allegiant Air Logo
1:56 pm - 6:00 pmDSM-RSW
3h 04mnonstop
Allegiant Air Logo
6:54 pm - 9:13 pmRSW-DSM
3h 19mnonstop
$215Allegiant Air
Find Deal
Sun, Nov 30 - Mon, Dec 8
Delta Logo
6:33 pm - 12:35 amDSM-RSW
5h 02m1 stop
Delta Logo
6:58 am - 10:43 amRSW-DSM
4h 45m1 stop
$257Delta
Find Deal
Tue, Dec 2 - Wed, Dec 3
American Airlines Logo
2:10 pm - 8:06 pmDSM-RSW
4h 56m1 stop
American Airlines Logo
8:28 am - 4:14 pmRSW-DSM
8h 46m2 stops
$262American Airlines
Find Deal
Tue, Jan 20 - Tue, Jan 27
Delta Logo
6:33 pm - 12:35 amDSM-RSW
5h 02m1 stop
Delta Logo
5:38 pm - 10:33 pmRSW-DSM
5h 55m1 stop
$267Delta
Find Deal
Tue, Dec 2 - Mon, Dec 8
American Airlines Logo
2:10 pm - 8:06 pmDSM-RSW
4h 56m1 stop
American Airlines Logo
8:28 am - 4:14 pmRSW-DSM
8h 46m2 stops
$272American Airlines
Find Deal
Sat, Jan 17 - Wed, Jan 21
Southwest Logo
8:35 am - 5:00 pmDSM-RSW
7h 25m1 stop
Southwest Logo
8:00 am - 2:55 pmRSW-DSM
7h 55m1 stop
$277Southwest
Find Deal
Thu, Jan 22 - Sat, Jan 31
Southwest Logo
3:20 pm - 9:35 pmDSM-RSW
5h 15m1 stop
Southwest Logo
7:25 am - 2:55 pmRSW-DSM
8h 30m2 stops
$282Southwest
Find Deal
Thu, Jan 22 - Sat, Jan 31
United Airlines Logo
8:00 am - 2:53 pmDSM-RSW
5h 53m1 stop
United Airlines Logo
5:02 pm - 10:30 pmRSW-DSM
6h 28m1 stop
$284United Airlines
Find Deal
Fri, Jan 23 - Tue, Jan 27
United Airlines Logo
8:00 am - 2:53 pmDSM-RSW
5h 53m1 stop
United Airlines Logo
7:00 am - 4:28 pmRSW-DSM
10h 28m2 stops
$289United Airlines
Find Deal
Fri, Jan 23 - Tue, Jan 27

Allegiant Air flights from Des Moines to Fort Myers

Our best Allegiant Air deals on Des Moines to Fort Myers flight tickets
Allegiant Air
Nov 30
DSM1:56 pmDes Moines
3h 04m
RSW6:00 pmFort Myers SW Florida Intl
Dec 5
RSW6:50 pmFort Myers SW Florida Intl
3h 19m
DSM9:09 pmDes Moines
$161
Find similar
Allegiant Air
Nov 30
DSM1:56 pmDes Moines
3h 04m
RSW6:00 pmFort Myers SW Florida Intl
Dec 8
RSW6:54 pmFort Myers SW Florida Intl
3h 19m
DSM9:13 pmDes Moines
$215
Find similar
Allegiant Air
Dec 19
DSM1:56 pmDes Moines
3h 04m
RSW6:00 pmFort Myers SW Florida Intl
Dec 26
RSW6:54 pmFort Myers SW Florida Intl
3h 19m
DSM9:13 pmDes Moines
$270
Find similar

Delta flights from Des Moines to Fort Myers

Our best Delta deals on Des Moines to Fort Myers flight tickets
Delta
Dec 2
DSM6:33 pmDes Moines
5h 02m
1 stop
RSW12:35 amFort Myers SW Florida Intl
Dec 3
RSW6:58 amFort Myers SW Florida Intl
4h 45m
1 stop
DSM10:43 amDes Moines
$257
Find similar
Delta
Dec 2
DSM6:33 pmDes Moines
5h 02m
1 stop
RSW12:35 amFort Myers SW Florida Intl
Dec 8
RSW5:38 pmFort Myers SW Florida Intl
5h 55m
1 stop
DSM10:33 pmDes Moines
$267
Find similar
Delta
Nov 28
DSM5:15 pmDes Moines
6h 22m
1 stop
RSW12:37 amFort Myers SW Florida Intl
Dec 9
RSW6:58 amFort Myers SW Florida Intl
4h 45m
1 stop
DSM10:43 amDes Moines
$332
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Fort Myers that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Des Moines to Fort Myers that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Sun 11/30

1:56 pm-6:00 pm

Nonstop3h 04m

Fort Myers SW Florida Intl

Fri 12/5

6:50 pm-9:09 pm

Nonstop3h 19m

$161

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Sun 11/30

1:56 pm-6:00 pm

Nonstop3h 04m

Fort Myers SW Florida Intl

Mon 12/8

6:54 pm-9:13 pm

Nonstop3h 19m

$215

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Tue 12/2

6:33 pm-12:35 am

1 stop5h 02m

Fort Myers SW Florida Intl

Wed 12/3

6:58 am-10:43 am

1 stop4h 45m

$257

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Tue 1/20

2:10 pm-8:06 pm

1 stop4h 56m

Fort Myers SW Florida Intl

Tue 1/27

8:28 am-4:14 pm

2 stops8h 46m

$262

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Tue 12/2

6:33 pm-12:35 am

1 stop5h 02m

Fort Myers SW Florida Intl

Mon 12/8

5:38 pm-10:33 pm

1 stop5h 55m

$267

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Sat 1/17

2:10 pm-8:06 pm

1 stop4h 56m

Fort Myers SW Florida Intl

Wed 1/21

8:28 am-4:14 pm

2 stops8h 46m

$272

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Thu 1/22

8:35 am-5:00 pm

1 stop7h 25m

Fort Myers SW Florida Intl

Sat 1/31

8:00 am-2:55 pm

1 stop7h 55m

$277

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Thu 1/22

3:20 pm-9:35 pm

1 stop5h 15m

Fort Myers SW Florida Intl

Sat 1/31

7:25 am-2:55 pm

2 stops8h 30m

$282

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Fri 1/23

8:00 am-2:53 pm

1 stop5h 53m

Fort Myers SW Florida Intl

Tue 1/27

5:02 pm-10:30 pm

1 stop6h 28m

$284

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Fri 1/23

8:00 am-2:53 pm

1 stop5h 53m

Fort Myers SW Florida Intl

Tue 1/27

7:00 am-4:28 pm

2 stops10h 28m

$289

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Fort Myers from

How to get the cheapest flight ticket from Des Moines to Fort Myers

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Fort Myers?

In general, August is the cheapest month to fly from Des Moines to Fort Myers. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $316. If you are unable to visit Fort Myers during the month of August, then departing from Des Moines during the month October is also very affordable. Most momondo users find prices during this month for around $318.

What is the cheapest day to depart on your flight to Fort Myers?

The cheapest day to depart from Des Moines to Fort Myers is on a Tuesday when prices can be found for as low as $376. Flights from Des Moines to Fort Myers on a Sunday will generally be more expensive and average around $461. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Fort Myers?

The cheapest time of day to fly to Fort Myers is at noon when flights can be purchased for as low as $213. Flights in the morning are often more expensive with an average ticket price of $442.

What is the cheapest Des Moines to Fort Myers SW Florida Intl flight route?

Fly from Des Moines to Fort Myers SW Florida Intl for the best Des Moines - Fort Myers SW Florida Intl flight prices

How far in advance should I book a flight to Fort Myers?

You are more likely to see cheaper flights to Fort Myers from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Fort Myers for around $396 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Fort Myers from Des Moines for as low as $312 on momondo.

What cabin class options are available on Des Moines to Fort Myers SW Florida Intl flights?

There is only 1 cabin class available to choose from on Des Moines to Fort Myers SW Florida Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Des Moines to Fort Myers flights?

No. A direct flight is the cheapest option for a flight between Des Moines to Fort Myers.

How have Des Moines to Fort Myers flight prices changed over time?

As of September 2025, prices for Des Moines to Fort Myers flights are approximately 62% cheaper when compared to flights at the same time last year.

When to book flights from Des Moines to Fort Myers

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Fort Myers according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Fort Myers (DSM to RSW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Fort Myers

Fastest flight time

3h 04m

Direct flights

Mon, Tue, Thu and Sat

Airports in Fort Myers

1 airport
The fastest flight from Des Moines to Fort Myers takes 3h 04m
Direct flights go from Des Moines to Fort Myers on Monday, Tuesday, Thursday and Saturday. There are no airlines offering direct flights.
There is 1 airport near Fort Myers: Fort Myers SW Florida Intl (RSW)
Search flight deals

  • How far is Des Moines to Fort Myers SW Florida Intl by plane?

    A flight from Des Moines to Fort Myers SW Florida Intl will travel around 1228.7 mi. A reasonable flight in good conditions will take 3h 04m.

  • When did momondo last update prices for flights from Des Moines Airport to Fort Myers SW Florida Intl Airport?

    Prices for flights from Des Moines Airport to Fort Myers SW Florida Intl Airport are updated daily.

  • How many operators does momondo search for flights from Des Moines Airport to Fort Myers SW Florida Intl Airport?

  • How old do you have to be to fly from Des Moines Airport to Fort Myers SW Florida Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Fort Myers SW Florida Intl Airport.

  • What documentation or ID do you need to fly to Fort Myers SW Florida Intl Airport?

    The necessary travel and health documents for your Fort Myers SW Florida Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Des Moines to Fort Myers?

  • What is the most popular airline from Des Moines to Fort Myers?

Best airlines flying from Des Moines to Fort Myers

Compare and see reviews for airlines that fly from Des Moines to Fort Myers with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $142Free CancellationRating
7.2
699 reviews
Search Allegiant Air flights
DeltaPriceFrom $263Free CancellationRating
7.9
7,961 reviews
Search Delta flights
United AirlinesPriceFrom $284Free CancellationRating
7.4
8,926 reviews
Search United Airlines flights
American AirlinesPriceFrom $296Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
SouthwestPriceFrom $310Free CancellationRating
8.0
4,242 reviews
Search Southwest flights

Traveling to a place near Fort Myers?

Book flights to Fort Myers if you plan to visit one of these locations
Sanibel
Fort Myers Beach
Cape Coral
Captiva
Estero
North Fort Myers
Boca Grande
Lehigh Acres

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Fort Myers?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Fort Myers from Des Moines.

Can I find flights from Des Moines to Fort Myers with flexible booking policies on momondo?

momondo does allow users to show only those flights to Fort Myers from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Fort Myers?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Fort Myers from Des Moines.

I’m not ready to book a flight from Des Moines to Fort Myers right now. Can momondo alert me if prices change?

Price alerts on flights to Fort Myers from Des Moines are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Fort Myers trip

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