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Cheap flights from Des Moines to Los Angeles from $84

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Los Angeles departing on 11/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

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Allegiant Air Logo
9:00 am - 10:47 amDSM-SNA
3h 47mnonstop
Allegiant Air Logo
9:37 am - 2:54 pmSNA-DSM
3h 17mnonstop
$154Allegiant Air
Find Deal
dim., nov. 16 - jeu., nov. 20
Multiple Airlines Logo
7:58 pm - 12:42 pmDSM-SNA
18h 44m1 stop
Multiple Airlines Logo
9:36 am - 2:54 pmSNA-DSM
3h 18mnonstop
$177Multiple Airlines
Find Deal
ven., déc. 5 - dim., déc. 7
Multiple Airlines Logo
9:00 am - 10:47 amDSM-SNA
3h 47mnonstop
Multiple Airlines Logo
12:01 pm - 1:49 pmSNA-DSM
23h 48m1 stop
$180Multiple Airlines
Find Deal
dim., nov. 9 - jeu., nov. 13
Frontier Logo
7:58 pm - 12:42 pmDSM-SNA
18h 44m1 stop
Frontier Logo
11:53 am - 7:44 pmSNA-DSM
5h 51m1 stop
$181Frontier
Find Deal
lun., déc. 15 - ven., déc. 19
Allegiant Air Logo
9:00 am - 10:47 amDSM-SNA
3h 47mnonstop
Allegiant Air Logo
11:37 am - 4:59 pmSNA-DSM
3h 22mnonstop
$182Allegiant Air
Find Deal
dim., nov. 9 - jeu., nov. 13
Frontier Logo
7:58 pm - 12:42 pmDSM-SNA
18h 44m1 stop
Frontier Logo
11:53 am - 7:44 pmSNA-DSM
5h 51m1 stop
$184Frontier
Find Deal
lun., déc. 15 - ven., déc. 19
Frontier Logo
7:58 pm - 12:42 pmDSM-SNA
18h 44m1 stop
Frontier Logo
7:57 pm - 7:44 pmSNA-DSM
21h 47m2 stops
$186Frontier
Find Deal
lun., déc. 15 - dim., déc. 21
Frontier Logo
7:58 pm - 12:42 pmDSM-SNA
18h 44m1 stop
Frontier Logo
7:16 pm - 7:44 pmSNA-DSM
22h 28m2 stops
$188Frontier
Find Deal
lun., déc. 15 - ven., déc. 19
Multiple Airlines Logo
7:58 pm - 12:42 pmDSM-SNA
18h 44m1 stop
Multiple Airlines Logo
11:39 am - 3:31 pmSNA-DSM
25h 52m1 stop
$193Multiple Airlines
Find Deal
lun., déc. 15 - mer., déc. 17
Allegiant Air Logo
9:00 am - 10:47 amDSM-SNA
3h 47mnonstop
Allegiant Air Logo
11:37 am - 4:59 pmSNA-DSM
3h 22mnonstop
$199Allegiant Air
Find Deal
dim., nov. 9 - jeu., nov. 13

Allegiant Air flights from Des Moines to Santa Ana, California

Our best Allegiant Air deals on Des Moines to Santa Ana, California flight tickets
Allegiant Air
Nov 16
DSM9:00 amDes Moines
3h 47m
SNA10:47 amSanta Ana J. Wayne/Orange Cnty
Nov 20
SNA9:37 amSanta Ana J. Wayne/Orange Cnty
3h 17m
DSM2:54 pmDes Moines
$154
Find similar
Allegiant Air
Nov 9
DSM9:00 amDes Moines
3h 47m
SNA10:47 amSanta Ana J. Wayne/Orange Cnty
Nov 13
SNA11:37 amSanta Ana J. Wayne/Orange Cnty
3h 22m
DSM4:59 pmDes Moines
$182
Find similar
Allegiant Air
Nov 9
DSM9:00 amDes Moines
3h 47m
SNA10:47 amSanta Ana J. Wayne/Orange Cnty
Nov 13
SNA11:37 amSanta Ana J. Wayne/Orange Cnty
3h 22m
DSM4:59 pmDes Moines
$190
Find similar

Frontier flights from Des Moines to Santa Ana, California

Our best Frontier deals on Des Moines to Santa Ana, California flight tickets
Frontier
Dec 15
DSM7:58 pmDes Moines
18h 44m
1 stop
SNA12:42 pmSanta Ana J. Wayne/Orange Cnty
Dec 19
SNA11:53 amSanta Ana J. Wayne/Orange Cnty
5h 51m
1 stop
DSM7:44 pmDes Moines
$181
Find similar
Frontier
Dec 15
DSM7:58 pmDes Moines
18h 44m
1 stop
SNA12:42 pmSanta Ana J. Wayne/Orange Cnty
Dec 19
SNA11:53 amSanta Ana J. Wayne/Orange Cnty
5h 51m
1 stop
DSM7:44 pmDes Moines
$184
Find similar
Frontier
Dec 15
DSM7:58 pmDes Moines
18h 44m
1 stop
SNA12:42 pmSanta Ana J. Wayne/Orange Cnty
Dec 21
SNA7:57 pmSanta Ana J. Wayne/Orange Cnty
21h 47m
2 stops
DSM7:44 pmDes Moines
$186
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated octobre 29, 2025.
Use the filters below to find and compare flights from Des Moines to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

dim. 11/16

9:00 am-10:47 am

Nonstop3h 47m

Santa Ana J. Wayne/Orange Cnty

jeu. 11/20

9:37 am-2:54 pm

Nonstop3h 17m

$154

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

ven. 12/5

7:58 pm-12:42 pm

1 stop18h 44m

Santa Ana J. Wayne/Orange Cnty

dim. 12/7

9:36 am-2:54 pm

Nonstop3h 18m

$177

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

dim. 11/9

9:00 am-10:47 am

Nonstop3h 47m

Santa Ana J. Wayne/Orange Cnty

jeu. 11/13

12:01 pm-1:49 pm

1 stop23h 48m

$180

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

lun. 12/15

7:58 pm-12:42 pm

1 stop18h 44m

Santa Ana J. Wayne/Orange Cnty

ven. 12/19

11:53 am-7:44 pm

1 stop5h 51m

$181

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

dim. 11/9

9:00 am-10:47 am

Nonstop3h 47m

Santa Ana J. Wayne/Orange Cnty

jeu. 11/13

11:37 am-4:59 pm

Nonstop3h 22m

$182

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

lun. 12/15

7:58 pm-12:42 pm

1 stop18h 44m

Santa Ana J. Wayne/Orange Cnty

ven. 12/19

11:53 am-7:44 pm

1 stop5h 51m

$184

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

lun. 12/15

7:58 pm-12:42 pm

1 stop18h 44m

Santa Ana J. Wayne/Orange Cnty

dim. 12/21

7:57 pm-7:44 pm

2 stops21h 47m

$186

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

lun. 12/15

7:58 pm-12:42 pm

1 stop18h 44m

Santa Ana J. Wayne/Orange Cnty

ven. 12/19

7:16 pm-7:44 pm

2 stops22h 28m

$188

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

lun. 12/15

7:58 pm-12:42 pm

1 stop18h 44m

Santa Ana J. Wayne/Orange Cnty

mer. 12/17

11:39 am-3:31 pm

1 stop25h 52m

$193

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

dim. 11/9

9:00 am-10:47 am

Nonstop3h 47m

Santa Ana J. Wayne/Orange Cnty

jeu. 11/13

11:37 am-4:59 pm

Nonstop3h 22m

$199

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Des Moines to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana, California?

In general, September is the cheapest month to fly from Des Moines to Santa Ana, California. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $131. If you aren’t able to travel during the month of September, then book flights to Santa Ana, California from Des Moines during April instead. Flights to Santa Ana, California in April, while not as cheap as those in September, still average around $243.

What is the cheapest day to depart on your flight to Santa Ana, California?

The cheapest day to depart from Des Moines to Santa Ana, California is on a Sunday. Travelers who choose to depart for Santa Ana, California on a Sunday will often find tickets for as low as $140. The most expensive day to fly to Santa Ana, California is Tuesday, with ticket prices averaging around $349.

What is the cheapest time of day to depart on your flight to Santa Ana, California?

In the afternoon is the cheapest time of day to fly from Des Moines to Santa Ana, California when you can find flight prices for as low as $135. Flying to Santa Ana, California in the afternoon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Santa Ana, California is in the morning when prices are around $216.

What is the cheapest Des Moines to Santa Ana J. Wayne/Orange Cnty flight route?

Fly from Des Moines to Santa Ana J. Wayne/Orange Cnty for the best Des Moines - Santa Ana J. Wayne/Orange Cnty flight prices

How far in advance should I book a flight to Santa Ana, California?

You are more likely to see cheaper flights to Santa Ana, California from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Santa Ana, California for around $318 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santa Ana, California from Des Moines for as low as $134 on momondo.

What cabin class options are available on Des Moines to Santa Ana J. Wayne/Orange Cnty flights?

There is only 1 cabin class available to choose from on Des Moines to Santa Ana J. Wayne/Orange Cnty flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Des Moines to Santa Ana, California flights?

No. A direct flight is the cheapest option for a flight between Des Moines to Santa Ana, California.

How have Des Moines to Santa Ana, California flight prices changed over time?

As of October 2025, prices for Des Moines to Santa Ana, California flights are approximately 22% cheaper when compared to flights at the same time last year.

When to book flights from Des Moines to Santa Ana, California

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Santa Ana, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Santa Ana, California (DSM to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Santa Ana, California

Best Price Found

$178

Fastest flight time

3h 46m

Direct flights

Mon, Wed, Fri and Sat

Airports in Santa Ana, California

1 airport
The best flight deal from Des Moines to Santa Ana, California found on momondo in the last 72 hours is $178
The fastest flight from Des Moines to Santa Ana, California takes 3h 46m
Direct flights go from Des Moines to Santa Ana, California on Monday, Wednesday, Friday and Saturday. The only airline offering direct flights is Allegiant Air.
There is 1 airport near Santa Ana, California: Santa Ana J. Wayne/Orange Cnty (SNA)
Search flight deals

  • How far is Des Moines to Santa Ana J. Wayne/Orange Cnty by plane?

    The straight-line distance from Des Moines to Santa Ana J. Wayne/Orange Cnty is 1425.0 mi. Flights usually cover this in 3h 46m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Des Moines Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Des Moines Airport to Santa Ana J. Wayne/Orange Cnty Airport refresh daily.

  • How many operators does momondo search for flights from Des Moines Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Des Moines Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The travel and health documents you'll need for your trip to Santa Ana J. Wayne/Orange Cnty Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santa Ana J. Wayne/Orange Cnty Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Des Moines to Santa Ana, California?

  • What is the most popular airline from Des Moines to Santa Ana, California?

Best airlines flying from Des Moines to Santa Ana, California

Compare and see reviews for airlines that fly from Des Moines to Santa Ana, California with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $108Free CancellationRating
7.2
695 reviews
Search Allegiant Air flights
DeltaPriceFrom $130Free CancellationRating
7.9
7,992 reviews
Search Delta flights
United AirlinesPriceFrom $260Free CancellationRating
7.4
8,999 reviews
Search United Airlines flights
American AirlinesPriceFrom $286Free CancellationRating
7.2
11,032 reviews
Search American Airlines flights
SouthwestPriceFrom $340Free CancellationRating
8.0
4,241 reviews
Search Southwest flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
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Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Santa Ana?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Des Moines to Santa Ana for you.

Can I find flights from Des Moines to Santa Ana with flexible booking policies on momondo?

Yes. All flights to Santa Ana from Des Moines on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Des Moines to Santa Ana?

momondo helps you find the best flight between Des Moines and Santa Ana by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Santa Ana right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Santa Ana flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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