Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Des Moines to Los Angeles from $74

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Los Angeles departing on 6/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Des Moines to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
7:00 am - 8:42 am
DSM
-
SNA
3h 42mnonstop
Allegiant Air Logo
12:26 pm - 5:43 pm
SNA
-
DSM
3h 17mnonstop
$180Allegiant Air
Thu, Aug 13 - Thu, Aug 20
Allegiant Air Logo
10:00 am - 11:37 am
DSM
-
SNA
3h 37mnonstop
Allegiant Air Logo
12:27 pm - 5:44 pm
SNA
-
DSM
3h 17mnonstop
$197Allegiant Air
Thu, Sep 17 - Sun, Sep 20
Allegiant Air Logo
8:00 am - 9:42 am
DSM
-
SNA
3h 42mnonstop
Allegiant Air Logo
10:32 am - 3:51 pm
SNA
-
DSM
3h 19mnonstop
$216Allegiant Air
Thu, May 28 - Sun, May 31
Allegiant Air Logo
9:30 am - 11:08 am
DSM
-
SNA
3h 38mnonstop
Allegiant Air Logo
11:58 am - 5:12 pm
SNA
-
DSM
3h 14mnonstop
$221Allegiant Air
Sat, Jun 20 - Sat, Jun 27
Multiple Airlines Logo
7:00 am - 8:42 am
DSM
-
SNA
3h 42mnonstop
Multiple Airlines Logo
8:10 pm - 6:48 pm
SNA
-
DSM
20h 38m
1 stop
$222Multiple Airlines
Thu, Aug 13 - Thu, Aug 20
Allegiant Air Logo
8:00 am - 9:42 am
DSM
-
SNA
3h 42mnonstop
Allegiant Air Logo
10:32 am - 3:51 pm
SNA
-
DSM
3h 19mnonstop
$225Allegiant Air
Thu, May 28 - Sun, May 31
Allegiant Air Logo
8:00 am - 9:42 am
DSM
-
SNA
3h 42mnonstop
Allegiant Air Logo
10:32 am - 3:51 pm
SNA
-
DSM
3h 19mnonstop
$235Allegiant Air
Thu, May 28 - Sun, May 31
Allegiant Air Logo
7:00 am - 8:38 am
DSM
-
SNA
3h 38mnonstop
Allegiant Air Logo
9:28 am - 2:42 pm
SNA
-
DSM
3h 14mnonstop
$255Allegiant Air
Sun, Jun 21 - Thu, Jun 25
Allegiant Air Logo
8:00 am - 9:42 am
DSM
-
SNA
3h 42mnonstop
Allegiant Air Logo
11:58 am - 5:12 pm
SNA
-
DSM
3h 14mnonstop
$256Allegiant Air
Thu, May 28 - Sat, Jun 27
Allegiant Air Logo
7:00 am - 8:38 am
DSM
-
SNA
3h 38mnonstop
Allegiant Air Logo
9:28 am - 2:42 pm
SNA
-
DSM
3h 14mnonstop
$259Allegiant Air
Sun, Jun 21 - Thu, Jun 25

Allegiant Air flights from Des Moines to Santa Ana, California

Our best Allegiant Air deals on Des Moines to Santa Ana, California flight tickets
Allegiant Air
Aug 13
DSM7:00 amDes Moines
3h 42m
SNA8:42 amSanta Ana J. Wayne/Orange Cnty
Aug 20
SNA12:26 pmSanta Ana J. Wayne/Orange Cnty
3h 17m
DSM5:43 pmDes Moines
$180
Allegiant Air
Sep 17
DSM10:00 amDes Moines
3h 37m
SNA11:37 amSanta Ana J. Wayne/Orange Cnty
Sep 20
SNA12:27 pmSanta Ana J. Wayne/Orange Cnty
3h 17m
DSM5:44 pmDes Moines
$197
Allegiant Air
May 28
DSM8:00 amDes Moines
3h 42m
SNA9:42 amSanta Ana J. Wayne/Orange Cnty
May 31
SNA10:32 amSanta Ana J. Wayne/Orange Cnty
3h 19m
DSM3:51 pmDes Moines
$216

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 16, 2026.
Use the filters below to find and compare flights from Des Moines to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Thu 8/13

7:00 am-8:42 am

Nonstop3h 42m

Santa Ana J. Wayne/Orange Cnty

Thu 8/20

12:26 pm-5:43 pm

Nonstop3h 17m

$180

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Thu 9/17

10:00 am-11:37 am

Nonstop3h 37m

Santa Ana J. Wayne/Orange Cnty

Sun 9/20

12:27 pm-5:44 pm

Nonstop3h 17m

$197

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Thu 5/28

8:00 am-9:42 am

Nonstop3h 42m

Santa Ana J. Wayne/Orange Cnty

Sun 5/31

10:32 am-3:51 pm

Nonstop3h 19m

$216
Quickest round-trip

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Sat 6/20

9:30 am-11:08 am

Nonstop3h 38m

Santa Ana J. Wayne/Orange Cnty

Sat 6/27

11:58 am-5:12 pm

Nonstop3h 14m

$221

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Thu 8/13

7:00 am-8:42 am

Nonstop3h 42m

Santa Ana J. Wayne/Orange Cnty

Thu 8/20

8:10 pm-6:48 pm

1 stop20h 38m

$222

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Thu 5/28

8:00 am-9:42 am

Nonstop3h 42m

Santa Ana J. Wayne/Orange Cnty

Sun 5/31

10:32 am-3:51 pm

Nonstop3h 19m

$225

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Thu 5/28

8:00 am-9:42 am

Nonstop3h 42m

Santa Ana J. Wayne/Orange Cnty

Sun 5/31

10:32 am-3:51 pm

Nonstop3h 19m

$235

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Sun 6/21

7:00 am-8:38 am

Nonstop3h 38m

Santa Ana J. Wayne/Orange Cnty

Thu 6/25

9:28 am-2:42 pm

Nonstop3h 14m

$255

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Thu 5/28

8:00 am-9:42 am

Nonstop3h 42m

Santa Ana J. Wayne/Orange Cnty

Sat 6/27

11:58 am-5:12 pm

Nonstop3h 14m

$256

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Sun 6/21

7:00 am-8:38 am

Nonstop3h 38m

Santa Ana J. Wayne/Orange Cnty

Thu 6/25

9:28 am-2:42 pm

Nonstop3h 14m

$259

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Los Angeles from

How to get the cheapest flight ticket from Des Moines to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Des Moines and Santa Ana, California?

What is the cheapest month to fly to Santa Ana, California?

In general, January is the cheapest month to fly from Des Moines to Santa Ana, California. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $158. If you aren’t able to travel during the month of January, then book flights to Santa Ana, California from Des Moines during September instead. Flights to Santa Ana, California in September, while not as cheap as those in January, still average around $164.

What is the cheapest day to depart on your flight to Santa Ana, California?

The cheapest day to depart from Des Moines to Santa Ana, California is on a Thursday. Travelers who choose to depart for Santa Ana, California on a Thursday will often find tickets for as low as $188. The most expensive day to fly to Santa Ana, California is Tuesday, with ticket prices averaging around $450.

What is the cheapest time of day to depart on your flight to Santa Ana, California?

In the afternoon is the cheapest time of day to fly from Des Moines to Santa Ana, California when you can find flight prices for as low as $163. Flying to Santa Ana, California in the afternoon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Santa Ana, California is in the morning when prices are around $209.

What is the cheapest Des Moines to Santa Ana J. Wayne/Orange Cnty flight route?

Fly from Des Moines to Santa Ana J. Wayne/Orange Cnty for the best Des Moines - Santa Ana J. Wayne/Orange Cnty flight prices

How far in advance should I book a flight from Des Moines to Santa Ana, California?

You are more likely to see cheaper flights to Santa Ana, California from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Santa Ana, California for around $320 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santa Ana, California from Des Moines for as low as $165 on momondo.

Can stopping save me money on Des Moines to Santa Ana, California flights?

No. A direct flight is the cheapest option for a flight between Des Moines to Santa Ana, California.

How have Des Moines to Santa Ana, California flight prices changed over time?

As of May 2026, prices for Des Moines to Santa Ana, California flights are approximately 10% cheaper when compared to flights at the same time last year.

When to book flights from Des Moines to Santa Ana, California

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Santa Ana, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Santa Ana, California (DSM to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Santa Ana, California

Best Price Found

$73

Fastest flight time

3h 33m

Direct flights

Mon, Fri and Sun

Airports in Santa Ana, California

1 airport
The best one-way flight to Santa Ana, California from Des Moines in the past 72 hours is $73. The best round-trip flight deal from Des Moines to Santa Ana, California found on momondo in the last 72 hours is $186.
The fastest flight from Des Moines to Santa Ana, California takes 3h 33m
Direct flights go from Des Moines to Santa Ana, California on Monday, Friday and Sunday. The only airline offering direct flights is Allegiant Air.
There is 1 airport in Santa Ana, California. From Des Moines there are direct flights to Santa Ana J. Wayne/Orange Cnty (SNA).
Search flight deals

Frequently asked questions about flying from Des Moines to Santa Ana, California

  • How far is Des Moines to Santa Ana J. Wayne/Orange Cnty by plane?

    The straight-line distance from Des Moines to Santa Ana J. Wayne/Orange Cnty is 1425.0 mi. Flights usually cover this in 3h 33m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Des Moines Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Des Moines Airport to Santa Ana J. Wayne/Orange Cnty Airport refresh daily.

  • How many operators does momondo search for flights from Des Moines Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Des Moines Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The travel and health documents you'll need for your trip to Santa Ana J. Wayne/Orange Cnty Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santa Ana J. Wayne/Orange Cnty Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Des Moines to Santa Ana, California?

  • What is the most popular airline from Des Moines to Santa Ana, California?

Best airlines flying from Des Moines to Santa Ana, California

Compare and see reviews for airlines that fly from Des Moines to Santa Ana, California with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $108Free CancellationRating
7.3
709 reviews
Search Allegiant Air flights
United AirlinesPriceFrom $268Free CancellationRating
7.4
9,729 reviews
Search United Airlines flights
American AirlinesPriceFrom $286Free CancellationRating
7.1
11,662 reviews
Search American Airlines flights
SouthwestPriceFrom $340Free CancellationRating
8.0
4,294 reviews
Search Southwest flights

  • Allegiant Air Flights From Des Moines to Santa Ana, California

    Across 2 Allegiant Air flights from Des Moines to Santa Ana, California this week, the average price was $201, with the best Allegiant Air deals starting from $108 round-trip. 709 users have rated Allegiant Air on momondo, with an average score of 7.3/10.

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Santa Ana?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Des Moines to Santa Ana for you.

Can I find flights from Des Moines to Santa Ana with flexible booking policies on momondo?

Yes. All flights to Santa Ana from Des Moines on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Des Moines to Santa Ana?

momondo helps you find the best flight between Des Moines and Santa Ana by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Santa Ana right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Santa Ana flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Santa Ana, California trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Mon 6/15
Mon 6/22
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States