Cheap flights from San Francisco to Los Angeles from $99

The cheapest month to fly to Santa Ana from San Francisco is in April. Flight prices, which tend to average around $167, are often lower during this time because this is during the off-season. The month of May is another great option to travel to Santa Ana, with average flight prices from San Francisco averaging around $167.

On average, the least expensive day to fly to Santa Ana from San Francisco is on a Tuesday. momondo users have found tickets for Tuesday departures for as low as $183. However, this price may fluctuate depending on the airline, the season, and holidays. On the other hand, Friday is the most expensive day to depart from San Francisco because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $228.

Our data shows that the cheapest San Francisco to Santa Ana flights are usually those with departure times at noon. Our users have found flights to Santa Ana at noon for as low as $170. Try not to purchase tickets in the evening because they tend to be around $271. Of course, these prices can vary depending on the time of year and what airport you fly to.

Fly from San Francisco to Santa Ana J. Wayne/Orange Cnty for the best San Francisco - Santa Ana J. Wayne/Orange Cnty flight prices

You are more likely to see cheaper flights to Santa Ana from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Santa Ana for around $219 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santa Ana from San Francisco for as low as $166 on momondo.

There are 4 cabin classes available to choose from on San Francisco to Santa Ana J. Wayne/Orange Cnty flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

United Airlines, Alaska Airlines, and Delta are the most popular carriers operating from San Francisco to Santa Ana J. Wayne/Orange Cnty

Alaska Airlines, Frontier and Southwest are the top three most popular airlines that fly to Santa Ana from San Francisco according to our data. Alaska Airlines is the first choice among our users, with 27% of people opting to fly with this airline when traveling to Santa Ana. Keep in mind that there are 11 different airlines that fly to Santa Ana on a routine basis, so you have a few additional options to choose from.

Historically, on average around 13% of flights between San Francisco and Santa Ana have experienced a delay on any given week. The average delay length over the past 12 months has been 120 minutes.

Generally, flights departing in the morning tend to experience fewer delays. Flights at night have, in the past, seen delays more frequently in comparison.

Saturday is statistically the day of the week which experiences the fewest number of delays on this flight route. Friday has historically seen more delays on average compared to the rest of the week.

According to our data, United Airlines have had the least number of delays on this route over the last 12 months; with about 9% of their flights experiencing any sort of delay.

The number of flights available between San Francisco and Santa Ana is 41 per day as of February 2026. The most frequent departure time is 1:00PM, with 51% of daily flights leaving in the afternoon.

As of February 2026, 288 flights take off from San Francisco and land in Santa Ana each week. The most common flight departure day for this route is Thu, with 16% of weekly flights taking off on this day.