Latest deals
Insights
When to book
FAQs
Price Alerts

Cheap flights from Mayagüez to San Diego from $1,672

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Mayagüez to San Diego departing on 5/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Mayagüez to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
1:19 pm - 9:42 am
MAZ
-
SAN
23h 23m
2 stops
United Airlines Logo
10:20 pm - 4:11 pm
SAN
-
MAZ
14h 51m
2 stops
$1,672United Airlines
Tue, May 5 - Sat, May 9
United Airlines Logo
1:19 pm - 3:33 pm
MAZ
-
SAN
29h 14m
2 stops
United Airlines Logo
10:20 pm - 4:11 pm
SAN
-
MAZ
14h 51m
2 stops
$1,692United Airlines
Tue, May 5 - Sat, May 9
United Airlines Logo
1:19 pm - 3:39 pm
MAZ
-
SAN
29h 20m
3 stops
United Airlines Logo
10:20 pm - 4:11 pm
SAN
-
MAZ
14h 51m
2 stops
$1,708United Airlines
Tue, May 5 - Sat, May 9
United Airlines Logo
1:19 pm - 8:38 pm
MAZ
-
SAN
34h 19m
3 stops
United Airlines Logo
10:55 am - 4:11 pm
SAN
-
MAZ
50h 16m
3 stops
$2,008United Airlines
Tue, May 5 - Sat, May 9
United Airlines Logo
1:19 pm - 6:51 pm
MAZ
-
SAN
32h 32m
2 stops
United Airlines Logo
10:20 pm - 4:11 pm
SAN
-
MAZ
14h 51m
2 stops
$2,111United Airlines
Tue, Apr 21 - Sat, Apr 25
United Airlines Logo
1:19 pm - 8:39 pm
MAZ
-
SAN
34h 20m
3 stops
United Airlines Logo
4:21 pm - 4:11 pm
SAN
-
MAZ
44h 50m
3 stops
$2,177United Airlines
Tue, Apr 21 - Sat, Apr 25

United Airlines flights from Mayagüez to San Diego

Our best United Airlines deals on Mayagüez to San Diego flight tickets
United Airlines
May 5
MAZ1:19 pmMayagüez Eugenio M De Hostos
29h 14m
2 stops
SAN3:33 pmSan Diego
May 9
SAN10:20 pmSan Diego
14h 51m
2 stops
MAZ4:11 pmMayagüez Eugenio M De Hostos
$1,692
United Airlines
May 5
MAZ1:19 pmMayagüez Eugenio M De Hostos
29h 20m
3 stops
SAN3:39 pmSan Diego
May 9
SAN10:20 pmSan Diego
14h 51m
2 stops
MAZ4:11 pmMayagüez Eugenio M De Hostos
$1,708
United Airlines
Apr 21
MAZ1:19 pmMayagüez Eugenio M De Hostos
25h 06m
2 stops
SAN11:25 amSan Diego
Apr 25
SAN4:21 pmSan Diego
20h 50m
3 stops
MAZ4:11 pmMayagüez Eugenio M De Hostos
$2,111

momondo Fare Finder

 
Customize your flight search to find flights from Mayagüez to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 7, 2026.
Use the filters below to find and compare flights from Mayagüez to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

MayagüezSan Diego

MAZ - SAN

MAZSAN

Mayagüez Eugenio M De Hostos

Tue 5/5

1:19 pm-9:42 am

2 stops23h 23m

San Diego

Sat 5/9

10:20 pm-4:11 pm

2 stops14h 51m

$1,672

MayagüezSan Diego

MAZ - SAN

MAZSAN

Mayagüez Eugenio M De Hostos

Tue 5/5

1:19 pm-3:33 pm

2 stops29h 14m

San Diego

Sat 5/9

10:20 pm-4:11 pm

2 stops14h 51m

$1,692

MayagüezSan Diego

MAZ - SAN

MAZSAN

Mayagüez Eugenio M De Hostos

Tue 5/5

1:19 pm-3:39 pm

3 stops29h 20m

San Diego

Sat 5/9

10:20 pm-4:11 pm

2 stops14h 51m

$1,708

MayagüezSan Diego

MAZ - SAN

MAZSAN

Mayagüez Eugenio M De Hostos

Tue 5/5

1:19 pm-8:38 pm

3 stops34h 19m

San Diego

Sat 5/9

10:55 am-4:11 pm

3 stops50h 16m

$2,008

MayagüezSan Diego

MAZ - SAN

MAZSAN

Mayagüez Eugenio M De Hostos

Tue 4/21

1:19 pm-6:51 pm

2 stops32h 32m

San Diego

Sat 4/25

10:20 pm-4:11 pm

2 stops14h 51m

$2,111

MayagüezSan Diego

MAZ - SAN

MAZSAN

Mayagüez Eugenio M De Hostos

Tue 4/21

1:19 pm-8:39 pm

3 stops34h 20m

San Diego

Sat 4/25

4:21 pm-4:11 pm

3 stops44h 50m

$2,177

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to San Diego from

How to get the cheapest flight ticket from Mayagüez to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to San Diego?

American Airlines, United Airlines and Delta are the top three most popular airlines that fly to San Diego from Mayagüez according to our data. American Airlines is the first choice among our users, with 52% of people opting to fly with this airline when traveling to San Diego. Keep in mind that there are 6 different airlines that fly to San Diego on a routine basis, so you have a few additional options to choose from.

When to book flights from Mayagüez to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Mayagüez to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Mayagüez to San Diego (MAZ to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mayagüez to San Diego

Fastest flight time

25h 06m

Direct flights

None
The fastest flight from Mayagüez to San Diego takes 25h 06m
There are no direct flights from Mayagüez to San Diego. There are no popular flight routes from Mayagüez to San Diego.
Search flight deals

Frequently asked questions about flying from Mayagüez to San Diego

  • How far is Mayagüez Eugenio M De Hostos to San Diego by plane?

    A flight from Mayagüez Eugenio M De Hostos to San Diego will travel around 3243.0 mi. 25h 06m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Mayagüez Eugenio M De Hostos Airport to San Diego Airport?

    Prices for flights from Mayagüez Eugenio M De Hostos Airport to San Diego Airport are updated daily.

  • How old do you have to be to fly from Mayagüez Eugenio M De Hostos Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Mayagüez Eugenio M De Hostos Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The travel and health documents required for your trip to San Diego Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at San Diego Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
Poway
San Ysidro
Imperial Beach
La Mesa
Lemon Grove
Borrego Springs
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Mayagüez to San Diego?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Mayagüez to San Diego. momondo saves you time and could save you money on your trip.

Can I find flights from Mayagüez to San Diego with flexible booking policies on momondo?

Flights from Mayagüez to San Diego with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Mayagüez to San Diego?

momondo helps you find the best flight between Mayagüez and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Mayagüez to San Diego right now. Can momondo alert me if prices change?

If you are simply researching potential flights to San Diego, momondo offers a useful price alert feature which will track prices for flights to San Diego from Mayagüez and alert you when they change.

An easier way to manage your San Diego trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Thu 5/7
Thu 5/14
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States