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Cheap flights from Islip, New York to San Diego from $142

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Islip, New York to San Diego departing on 1/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Islip, New York to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
3:45 pm - 9:00 pm
ISP
-
SAN
8h 15m1 stop
Southwest Logo
6:50 am - 4:35 pm
SAN
-
ISP
6h 45m1 stop
$410Southwest
Wed, Jan 14 - Sun, Jan 25
Southwest Logo
3:45 pm - 9:00 pm
ISP
-
SAN
8h 15m1 stop
Southwest Logo
7:05 am - 10:20 pm
SAN
-
ISP
12h 15m2 stops
$415Southwest
Wed, Jan 14 - Sun, Jan 25
Southwest Logo
3:45 pm - 11:05 pm
ISP
-
SAN
10h 20m2 stops
Southwest Logo
7:05 am - 10:20 pm
SAN
-
ISP
12h 15m2 stops
$420Southwest
Wed, Jan 14 - Sun, Jan 25
Southwest Logo
5:30 am - 2:10 pm
ISP
-
SAN
11h 40m2 stops
Southwest Logo
10:50 am - 11:55 pm
SAN
-
ISP
10h 05m1 stop
$992Southwest
Sat, Dec 27 - Sun, Dec 28
Southwest Logo
5:30 am - 2:10 pm
ISP
-
SAN
11h 40m2 stops
Southwest Logo
9:45 am - 11:55 pm
SAN
-
ISP
11h 10m2 stops
$997Southwest
Sat, Dec 27 - Sun, Dec 28
Breeze Airways Logo
10:38 am - 12:27 pm
ISP
-
SAN
28h 49m1 stop
Breeze Airways Logo
1:12 pm - 11:10 am
SAN
-
ISP
42h 58m3 stops
$1,056Breeze Airways
Thu, Jan 1 - Mon, Jan 5
Multiple Airlines Logo
7:25 am - 7:53 pm
ISP
-
SAN
15h 28m2 stops
Multiple Airlines Logo
8:44 pm - 11:05 am
SAN
-
ISP
11h 21m1 stop
$1,248Multiple Airlines
Thu, Jan 1 - Mon, Jan 5
Breeze Airways Logo
11:40 am - 12:27 pm
ISP
-
SAN
27h 47m3 stops
Breeze Airways Logo
1:12 pm - 11:10 am
SAN
-
ISP
42h 58m3 stops
$1,294Breeze Airways
Thu, Jan 1 - Mon, Jan 5
Multiple Airlines Logo
9:59 am - 7:19 pm
ISP
-
SAN
12h 20m1 stop
Multiple Airlines Logo
8:44 pm - 11:05 am
SAN
-
ISP
11h 21m1 stop
$1,322Multiple Airlines
Thu, Jan 1 - Mon, Jan 5
Southwest Logo
12:20 pm - 8:40 pm
ISP
-
SAN
11h 20m1 stop
Southwest Logo
6:20 am - 5:15 pm
SAN
-
ISP
7h 55m1 stop
$1,377Southwest
Sat, Dec 27 - Sun, Dec 28

Southwest flights from Islip, New York to San Diego

Our best Southwest deals on Islip, New York to San Diego flight tickets
Southwest
Jan 14
ISP3:45 pmIslip Long Island
8h 15m
1 stop
SAN9:00 pmSan Diego
Jan 25
SAN6:50 amSan Diego
6h 45m
1 stop
ISP4:35 pmIslip Long Island
$410
Find similar
Southwest
Jan 14
ISP3:45 pmIslip Long Island
8h 15m
1 stop
SAN9:00 pmSan Diego
Jan 25
SAN7:05 amSan Diego
12h 15m
2 stops
ISP10:20 pmIslip Long Island
$415
Find similar
Southwest
Jan 14
ISP3:45 pmIslip Long Island
10h 20m
2 stops
SAN11:05 pmSan Diego
Jan 25
SAN7:05 amSan Diego
12h 15m
2 stops
ISP10:20 pmIslip Long Island
$420
Find similar

Breeze Airways flights from Islip, New York to San Diego

Our best Breeze Airways deals on Islip, New York to San Diego flight tickets
Breeze Airways
Jan 1
ISP10:38 amIslip Long Island
28h 49m
1 stop
SAN12:27 pmSan Diego
Jan 5
SAN1:12 pmSan Diego
42h 58m
3 stops
ISP11:10 amIslip Long Island
$1,056
Find similar
Breeze Airways
Jan 1
ISP11:40 amIslip Long Island
27h 47m
3 stops
SAN12:27 pmSan Diego
Jan 5
SAN1:12 pmSan Diego
42h 58m
3 stops
ISP11:10 amIslip Long Island
$1,294
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Islip, New York to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Islip, New York to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

IslipSan Diego

ISP - SAN

ISPSAN

Islip Long Island

Wed 1/14

3:45 pm-9:00 pm

1 stop8h 15m

San Diego

Sun 1/25

6:50 am-4:35 pm

1 stop6h 45m

$410

IslipSan Diego

ISP - SAN

ISPSAN

Islip Long Island

Wed 1/14

3:45 pm-9:00 pm

1 stop8h 15m

San Diego

Sun 1/25

7:05 am-10:20 pm

2 stops12h 15m

$415

IslipSan Diego

ISP - SAN

ISPSAN

Islip Long Island

Wed 1/14

3:45 pm-11:05 pm

2 stops10h 20m

San Diego

Sun 1/25

7:05 am-10:20 pm

2 stops12h 15m

$420

IslipSan Diego

ISP - SAN

ISPSAN

Islip Long Island

Sat 12/27

5:30 am-2:10 pm

2 stops11h 40m

San Diego

Sun 12/28

10:50 am-11:55 pm

1 stop10h 05m

$992

IslipSan Diego

ISP - SAN

ISPSAN

Islip Long Island

Sat 12/27

5:30 am-2:10 pm

2 stops11h 40m

San Diego

Sun 12/28

9:45 am-11:55 pm

2 stops11h 10m

$997

IslipSan Diego

ISP - SAN

ISPSAN

Islip Long Island

Thu 1/1

10:38 am-12:27 pm

1 stop28h 49m

San Diego

Mon 1/5

1:12 pm-11:10 am

3 stops42h 58m

$1,056

IslipSan Diego

ISP - SAN

ISPSAN

Islip Long Island

Thu 1/1

7:25 am-7:53 pm

2 stops15h 28m

San Diego

Mon 1/5

8:44 pm-11:05 am

1 stop11h 21m

$1,248

IslipSan Diego

ISP - SAN

ISPSAN

Islip Long Island

Thu 1/1

11:40 am-12:27 pm

3 stops27h 47m

San Diego

Mon 1/5

1:12 pm-11:10 am

3 stops42h 58m

$1,294

IslipSan Diego

ISP - SAN

ISPSAN

Islip Long Island

Thu 1/1

9:59 am-7:19 pm

1 stop12h 20m

San Diego

Mon 1/5

8:44 pm-11:05 am

1 stop11h 21m

$1,322

IslipSan Diego

ISP - SAN

ISPSAN

Islip Long Island

Sat 12/27

12:20 pm-8:40 pm

1 stop11h 20m

San Diego

Sun 12/28

6:20 am-5:15 pm

1 stop7h 55m

$1,377

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Islip, New York to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Islip, New York to San Diego is on a Tuesday. Travelers who choose to depart for San Diego on a Tuesday will often find tickets for as low as $373. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $474. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is at noon when flights can be purchased for as low as $357. Flights in the morning are often more expensive with an average ticket price of $410.

Can stopping save me money on Islip, New York to San Diego flights?

You could potentially save up to 37% on your flight if you consider stops on a Islip, New York to San Diego flight.

When to book flights from Islip, New York to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Islip, New York to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Islip, New York to San Diego (ISP to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Islip, New York to San Diego

Fastest flight time

11h 20m

Direct flights

None
The fastest flight from Islip, New York to San Diego takes 11h 20m
There are no direct flights from Islip, New York to San Diego. There are no popular flight routes from Islip, New York to San Diego.
Search flight deals

  • How far is Islip Long Island to San Diego by plane?

    Islip Long Island and San Diego are 2467.5 mi apart from one another. Flights usually cover this in 11h 20m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Islip Long Island Airport to San Diego Airport?

    Prices for flights from Islip Long Island Airport to San Diego Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Islip Long Island Airport to San Diego Airport?

  • How old do you have to be to fly from Islip Long Island Airport to San Diego Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Islip Long Island Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Islip, New York to San Diego?

Best airlines flying from Islip, New York to San Diego

Compare and see reviews for airlines that fly from Islip, New York to San Diego with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $350Free CancellationRating
7.9
4,250 reviews
Search Southwest flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
Poway
Imperial Beach
Borrego Springs
La Mesa
San Ysidro
Alpine
Lemon Grove
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Islip to San Diego?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Diego from Islip.

Can I find flights from Islip to San Diego with flexible booking policies on momondo?

Yes. All flights to San Diego from Islip on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Islip to San Diego?

momondo provides multiple filters to help you find the best flight to San Diego from Islip. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Islip to San Diego right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Islip to San Diego flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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