Cheap flights from Indianapolis to San Diego from $80

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indianapolis to San Diego departing on 9/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Indianapolis to San Diego (IND-SAN)

Cheap round-trip flights

Frontier Logo
5:01 pm - 4:42 pmIND-SAN
26h 41m2 stops
Frontier Logo
5:37 pm - 6:25 pmSAN-IND
21h 48m1 stop
$223Frontier
Find Deal
Sat, Sep 20 - Sun, Oct 5
 Logo
12:20 pm - 11:34 pmIND-SAN
14h 14m2 stops
 Logo
10:20 am - 4:14 pmSAN-IND
26h 54m1 stop
Sat, Sep 20 - Fri, Oct 3
Frontier Logo
8:39 pm - 11:50 pmIND-SAN
6h 11m1 stop
Frontier Logo
5:25 pm - 7:44 pmSAN-IND
47h 19m2 stops
$225Frontier
Find Deal
Thu, Nov 13 - Fri, Nov 14
Frontier Logo
4:20 pm - 7:34 pmIND-SAN
30h 14m2 stops
Frontier Logo
8:08 pm - 12:57 pmSAN-IND
13h 49m1 stop
$226Frontier
Find Deal
Sat, Nov 1 - Sun, Nov 9
Frontier Logo
8:39 pm - 4:57 pmIND-SAN
23h 18m2 stops
Frontier Logo
6:41 am - 7:44 pmSAN-IND
10h 03m1 stop
$228Frontier
Find Deal
Thu, Nov 13 - Mon, Nov 17
 Logo
11:24 am - 12:19 pmIND-SAN
27h 55m2 stops
 Logo
5:57 pm - 3:35 pmSAN-IND
18h 38m1 stop
Mon, Nov 3 - Fri, Nov 7
Spirit Airlines Logo
8:33 pm - 7:29 amIND-SAN
13h 56m1 stop
Spirit Airlines Logo
6:15 am - 6:57 pmSAN-IND
9h 42m1 stop
$234Spirit Airlines
Find Deal
Thu, Oct 2 - Thu, Oct 9
Spirit Airlines Logo
4:43 pm - 11:34 pmIND-SAN
9h 51m1 stop
Spirit Airlines Logo
6:15 am - 10:15 amSAN-IND
25h 00m2 stops
$244Spirit Airlines
Find Deal
Sat, Sep 20 - Wed, Sep 24
Spirit Airlines Logo
8:33 pm - 11:34 pmIND-SAN
6h 01m1 stop
Spirit Airlines Logo
10:05 am - 5:35 pmSAN-IND
28h 30m3 stops
$248Spirit Airlines
Find Deal
Thu, Oct 2 - Wed, Oct 8
Spirit Airlines Logo
6:23 pm - 11:17 pmIND-SAN
7h 54m1 stop
Spirit Airlines Logo
6:15 am - 6:57 pmSAN-IND
9h 42m1 stop
$257Spirit Airlines
Find Deal
Sat, Oct 11 - Thu, Oct 16

Frontier flights from Indianapolis to San Diego

Our best Frontier deals on Indianapolis to San Diego flight tickets
Frontier
Sep 20
IND5:01 pmIndianapolis
26h 41m
2 stops
SAN4:42 pmSan Diego
Oct 5
SAN5:37 pmSan Diego
21h 48m
1 stop
IND6:25 pmIndianapolis
Frontier
Sep 12
IND8:54 pmIndianapolis
28h 30m
1 stop
SAN10:24 pmSan Diego
Sep 15
SAN10:20 amSan Diego
6h 44m
1 stop
IND8:04 pmIndianapolis
Frontier
Nov 13
IND8:39 pmIndianapolis
6h 11m
1 stop
SAN11:50 pmSan Diego
Nov 14
SAN5:25 pmSan Diego
47h 19m
2 stops
IND7:44 pmIndianapolis

Spirit Airlines flights from Indianapolis to San Diego

Our best Spirit Airlines deals on Indianapolis to San Diego flight tickets
Spirit Airlines
Oct 2
IND8:33 pmIndianapolis
13h 56m
1 stop
SAN7:29 amSan Diego
Oct 9
SAN6:15 amSan Diego
9h 42m
1 stop
IND6:57 pmIndianapolis
Spirit Airlines
Sep 20
IND4:43 pmIndianapolis
9h 51m
1 stop
SAN11:34 pmSan Diego
Sep 24
SAN6:15 amSan Diego
25h 00m
2 stops
IND10:15 amIndianapolis
Spirit Airlines
Oct 2
IND8:33 pmIndianapolis
6h 01m
1 stop
SAN11:34 pmSan Diego
Oct 8
SAN10:05 amSan Diego
28h 30m
3 stops
IND5:35 pmIndianapolis

momondo Fare Finder

 
Customize your flight search to find flights from Indianapolis to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 3, 2025.
Use the filters below to find and compare flights from Indianapolis to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Sat 9/20

5:01 pm-4:42 pm

2 stops26h 41m

San Diego

Sun 10/5

5:37 pm-6:25 pm

1 stop21h 48m

$223

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Sat 9/20

12:20 pm-11:34 pm

2 stops14h 14m

San Diego

Fri 10/3

10:20 am-4:14 pm

1 stop26h 54m

$224

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Thu 11/13

8:39 pm-11:50 pm

1 stop6h 11m

San Diego

Fri 11/14

5:25 pm-7:44 pm

2 stops47h 19m

$225

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Sat 11/1

4:20 pm-7:34 pm

2 stops30h 14m

San Diego

Sun 11/9

8:08 pm-12:57 pm

1 stop13h 49m

$226

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Thu 11/13

8:39 pm-4:57 pm

2 stops23h 18m

San Diego

Mon 11/17

6:41 am-7:44 pm

1 stop10h 03m

$228

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Mon 11/3

11:24 am-12:19 pm

2 stops27h 55m

San Diego

Fri 11/7

5:57 pm-3:35 pm

1 stop18h 38m

$233

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Thu 10/2

8:33 pm-7:29 am

1 stop13h 56m

San Diego

Thu 10/9

6:15 am-6:57 pm

1 stop9h 42m

$234

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Sat 9/20

4:43 pm-11:34 pm

1 stop9h 51m

San Diego

Wed 9/24

6:15 am-10:15 am

2 stops25h 00m

$244

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Thu 10/2

8:33 pm-11:34 pm

1 stop6h 01m

San Diego

Wed 10/8

10:05 am-5:35 pm

3 stops28h 30m

$248

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Sat 10/11

6:23 pm-11:17 pm

1 stop7h 54m

San Diego

Thu 10/16

6:15 am-6:57 pm

1 stop9h 42m

$257

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Indianapolis to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of May, then departing from Indianapolis during the month January is also very affordable. Most momondo users find prices during this month for around $312.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Indianapolis to San Diego is on a Tuesday. Travelers who choose to depart for San Diego on a Tuesday will often find tickets for as low as $375. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $542. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is in the evening when flights can be purchased for as low as $337. Flights at noon are often more expensive with an average ticket price of $547.

What is the cheapest Indianapolis to San Diego flight route?

Fly from Indianapolis to San Diego for the best Indianapolis - San Diego flight prices

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Indianapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $351 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Indianapolis for as low as $295 on momondo.

What cabin class options are available on Indianapolis to San Diego flights?

There is only 1 cabin class available to choose from on Indianapolis to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Indianapolis to San Diego flight prices changed over time?

As of September 2025, prices for Indianapolis to San Diego flights are approximately 10% cheaper when compared to flights at the same time last year.

When to book flights from Indianapolis to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Indianapolis to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Indianapolis to San Diego (IND to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to San Diego

Best Price Found

$147

Fastest flight time

4h 10m

Direct flights

Every day

Airports in San Diego

1 airport
The best one-way flight to San Diego from Indianapolis in the past 72 hours is $147. The best round-trip flight deal from Indianapolis to San Diego found on momondo in the last 72 hours is $315.
The fastest flight from Indianapolis to San Diego takes 4h 10m
Direct flights go from Indianapolis to San Diego every day.
There is 1 airport near San Diego: San Diego (SAN)
  • How far is Indianapolis to San Diego by plane?

    The distance between Indianapolis and San Diego is about 1783.7 mi. By plane, this route typically takes 5h 59m.

  • When did momondo last update prices for flights from Indianapolis Airport to San Diego Airport?

    Prices for flights from Indianapolis Airport to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Indianapolis Airport to San Diego Airport?

  • How old do you have to be to fly from Indianapolis Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Indianapolis Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Indianapolis to San Diego?

  • What is the most popular airline from Indianapolis to San Diego?

Best airlines flying from Indianapolis to San Diego

Compare and see reviews for airlines that fly from Indianapolis to San Diego with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $120Free CancellationRating
6.3
8,012 reviews
Search Spirit Airlines flights
FrontierPriceFrom $128Free CancellationRating
5.8
3,196 reviews
Search Frontier flights
DeltaPriceFrom $203Free CancellationRating
7.9
7,972 reviews
Search Delta flights
American AirlinesPriceFrom $220Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $231Free CancellationRating
7.4
8,937 reviews
Search United Airlines flights
SouthwestPriceFrom $269Free CancellationRating
8.0
4,238 reviews
Search Southwest flights
  • Southwest Flights From Indianapolis to San Diego

    Southwest operates around 5 flights from Indianapolis to San Diego every week. The average price of these flights found in the last 72 hours has been $430, but momondo users have found Southwest deals from Indianapolis to San Diego from as low as $269 round-trip. Southwest has been scored 8.0/10 in 4,238 reviews.

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
La Mesa
National City
Imperial Beach
Poway
San Ysidro
Borrego Springs
Alpine
Lemon Grove
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to San Diego?

It is quick and easy to find Indianapolis to San Diego flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to San Diego that suits you.

Can I find flights from Indianapolis to San Diego with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Indianapolis to San Diego flights to just show those with flexible booking policies.

How can momondo help me find flights from Indianapolis to San Diego?

momondo helps you find the best flight between Indianapolis and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Indianapolis to San Diego right now. Can momondo alert me if prices change?

Price alerts on flights to San Diego from Indianapolis are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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1 adult
Mon 9/8
Mon 9/15

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