Cheap flights from Indianapolis to San Diego from $78

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indianapolis to San Diego departing on 3/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Delta Logo
5:14 pm - 11:04 pm
IND
-
SAN
8h 50m
1 stop
Delta Logo
6:25 am - 4:34 pm
SAN
-
IND
7h 09m
1 stop
$257Delta
Wed, Mar 4 - Wed, Apr 29
Frontier Logo
8:32 pm - 12:08 am
IND
-
SAN
6h 36m
1 stop
Frontier Logo
9:07 pm - 12:57 pm
SAN
-
IND
12h 50m
1 stop
$260Frontier
Fri, Feb 27 - Sun, May 3
Multiple Airlines Logo
7:27 pm - 10:26 am
IND
-
SAN
17h 59m
2 stops
Multiple Airlines Logo
6:25 am - 7:42 pm
SAN
-
IND
10h 17m
1 stop
$261Multiple Airlines
Fri, Feb 27 - Mon, Apr 27
Multiple Airlines Logo
8:47 pm - 11:28 am
IND
-
SAN
17h 41m
1 stop
Multiple Airlines Logo
9:50 am - 8:32 am
SAN
-
IND
19h 42m
2 stops
$262Multiple Airlines
Fri, Feb 20 - Mon, Feb 23
Frontier Logo
8:32 pm - 11:28 am
IND
-
SAN
17h 56m
1 stop
Frontier Logo
6:55 am - 5:16 pm
SAN
-
IND
7h 21m
1 stop
$263Frontier
Fri, Feb 27 - Fri, May 1
Frontier Logo
8:33 pm - 12:08 am
IND
-
SAN
30h 35m
1 stop
Frontier Logo
8:39 pm - 7:38 pm
SAN
-
IND
43h 59m
2 stops
$264Frontier
Sun, Mar 15 - Sun, Mar 22
Frontier Logo
11:15 am - 8:50 am
IND
-
SAN
24h 35m
1 stop
Frontier Logo
6:55 am - 5:16 pm
SAN
-
IND
7h 21m
1 stop
$265Frontier
Thu, Feb 26 - Fri, May 1
Frontier Logo
8:33 pm - 12:08 am
IND
-
SAN
30h 35m
1 stop
Frontier Logo
10:13 pm - 7:38 pm
SAN
-
IND
18h 25m
2 stops
$266Frontier
Wed, Mar 11 - Mon, Mar 23
Alaska Airlines Logo
7:00 am - 1:41 pm
IND
-
SAN
9h 41m
1 stop
Alaska Airlines Logo
6:34 pm - 5:50 am
SAN
-
IND
8h 16m
1 stop
$267Alaska Airlines
Tue, Apr 21 - Wed, May 6
Frontier Logo
8:33 pm - 12:08 am
IND
-
SAN
6h 35m
1 stop
Frontier Logo
9:00 am - 7:57 pm
SAN
-
IND
7h 57m
1 stop
$268Frontier
Fri, Mar 6 - Mon, Mar 9

American Airlines flights from Indianapolis to San Diego

Our best American Airlines deals on Indianapolis to San Diego flight tickets
American Airlines
Feb 21
IND1:57 pmIndianapolis
9h 23m
1 stop
SAN8:20 pmSan Diego
Feb 24
SAN3:19 pmSan Diego
5h 59m
1 stop
IND12:18 amIndianapolis
$271
American Airlines
Feb 21
IND3:50 pmIndianapolis
9h 44m
1 stop
SAN10:34 pmSan Diego
Feb 22
SAN9:57 pmSan Diego
8h 35m
1 stop
IND9:32 amIndianapolis
$292
American Airlines
Feb 17
IND11:21 amIndianapolis
10h 06m
1 stop
SAN6:27 pmSan Diego
Feb 24
SAN6:20 amSan Diego
9h 12m
1 stop
IND6:32 pmIndianapolis
$298

Frontier flights from Indianapolis to San Diego

Our best Frontier deals on Indianapolis to San Diego flight tickets
Frontier
Feb 27
IND8:32 pmIndianapolis
6h 36m
1 stop
SAN12:08 amSan Diego
May 3
SAN9:07 pmSan Diego
12h 50m
1 stop
IND12:57 pmIndianapolis
$260
Frontier
Feb 27
IND8:32 pmIndianapolis
17h 56m
1 stop
SAN11:28 amSan Diego
May 1
SAN6:55 amSan Diego
7h 21m
1 stop
IND5:16 pmIndianapolis
$263
Frontier
Mar 16
IND4:05 pmIndianapolis
10h 19m
1 stop
SAN11:24 pmSan Diego
Mar 22
SAN8:39 pmSan Diego
43h 59m
2 stops
IND7:38 pmIndianapolis
$264

momondo Fare Finder

 
Customize your flight search to find flights from Indianapolis to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Indianapolis to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Wed 3/4

5:14 pm-11:04 pm

1 stop8h 50m

San Diego

Wed 4/29

6:25 am-4:34 pm

1 stop7h 09m

$257

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Fri 2/27

8:32 pm-12:08 am

1 stop6h 36m

San Diego

Sun 5/3

9:07 pm-12:57 pm

1 stop12h 50m

$260

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Fri 2/27

7:27 pm-10:26 am

2 stops17h 59m

San Diego

Mon 4/27

6:25 am-7:42 pm

1 stop10h 17m

$261

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Fri 2/20

8:47 pm-11:28 am

1 stop17h 41m

San Diego

Mon 2/23

9:50 am-8:32 am

2 stops19h 42m

$262

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Fri 2/27

8:32 pm-11:28 am

1 stop17h 56m

San Diego

Fri 5/1

6:55 am-5:16 pm

1 stop7h 21m

$263

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Sun 3/15

8:33 pm-12:08 am

1 stop30h 35m

San Diego

Sun 3/22

8:39 pm-7:38 pm

2 stops43h 59m

$264

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Thu 2/26

11:15 am-8:50 am

1 stop24h 35m

San Diego

Fri 5/1

6:55 am-5:16 pm

1 stop7h 21m

$265

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Wed 3/11

8:33 pm-12:08 am

1 stop30h 35m

San Diego

Mon 3/23

10:13 pm-7:38 pm

2 stops18h 25m

$266

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Tue 4/21

7:00 am-1:41 pm

1 stop9h 41m

San Diego

Wed 5/6

6:34 pm-5:50 am

1 stop8h 16m

$267

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Fri 3/6

8:33 pm-12:08 am

1 stop6h 35m

San Diego

Mon 3/9

9:00 am-7:57 pm

1 stop7h 57m

$268

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Indianapolis to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of September, then departing from Indianapolis during the month May is also very affordable. Most momondo users find prices during this month for around $304.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Indianapolis to San Diego is on a Wednesday. Travelers who choose to depart for San Diego on a Wednesday will often find tickets for as low as $403. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $562. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is in the morning when flights can be purchased for as low as $438. Flights at noon are often more expensive with an average ticket price of $544.

What is the cheapest Indianapolis to San Diego flight route?

Fly from Indianapolis to San Diego for the best Indianapolis - San Diego flight prices

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Indianapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $359 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Indianapolis for as low as $309 on momondo.

What cabin class options are available on Indianapolis to San Diego flights?

There is only 1 cabin class available to choose from on Indianapolis to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Indianapolis to San Diego flight prices changed over time?

As of February 2026, prices for Indianapolis to San Diego flights are approximately 14% cheaper when compared to flights at the same time last year.

When to book flights from Indianapolis to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Indianapolis to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Indianapolis to San Diego (IND to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to San Diego

Best Price Found

$232

Fastest flight time

4h 10m

Direct flights

Mon, Tue, Wed, Fri, Sat and Sun

Airports in San Diego

1 airport
The best one-way flight to San Diego from Indianapolis in the past 72 hours is $232. The best round-trip flight deal from Indianapolis to San Diego found on momondo in the last 72 hours is $421.
The fastest flight from Indianapolis to San Diego takes 4h 10m
Direct flights go from Indianapolis to San Diego on Monday, Tuesday, Wednesday, Friday, Saturday and Sunday. The only airline offering direct flights is Southwest.
There is 1 airport in San Diego. From Indianapolis there are direct flights to San Diego (SAN).
  • How far is Indianapolis to San Diego by plane?

    The distance between Indianapolis and San Diego is about 1783.7 mi. By plane, this route typically takes 4h 10m.

  • When did momondo last update prices for flights from Indianapolis Airport to San Diego Airport?

    Prices for flights from Indianapolis Airport to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Indianapolis Airport to San Diego Airport?

  • How old do you have to be to fly from Indianapolis Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Indianapolis Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Indianapolis to San Diego?

  • What is the most popular airline from Indianapolis to San Diego?

Best airlines flying from Indianapolis to San Diego

Compare and see reviews for airlines that fly from Indianapolis to San Diego with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $86Free CancellationRating
5.7
3,051 reviews
Search Frontier flights
Spirit AirlinesPriceFrom $124Free CancellationRating
6.3
8,396 reviews
Search Spirit Airlines flights
DeltaPriceFrom $203Free CancellationRating
7.9
8,132 reviews
Search Delta flights
American AirlinesPriceFrom $210Free CancellationRating
7.2
11,212 reviews
Search American Airlines flights
United AirlinesPriceFrom $220Free CancellationRating
7.4
9,229 reviews
Search United Airlines flights
SouthwestPriceFrom $274Free CancellationRating
8.0
4,271 reviews
Search Southwest flights
  • Southwest Flights From Indianapolis to San Diego

    Southwest operates around 4 flights from Indianapolis to San Diego every week. The average price of these flights found in the last 72 hours has been $424, but momondo users have found Southwest deals from Indianapolis to San Diego from as low as $274 round-trip. Southwest has been scored 8.0/10 in 4,272 reviews.

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
Poway
National City
Imperial Beach
San Ysidro
Borrego Springs
La Mesa
Alpine
Lemon Grove
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to San Diego?

It is quick and easy to find Indianapolis to San Diego flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to San Diego that suits you.

Can I find flights from Indianapolis to San Diego with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Indianapolis to San Diego flights to just show those with flexible booking policies.

How can momondo help me find flights from Indianapolis to San Diego?

momondo helps you find the best flight between Indianapolis and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Indianapolis to San Diego right now. Can momondo alert me if prices change?

Price alerts on flights to San Diego from Indianapolis are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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1 adult
Thu 3/5
Thu 3/12

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