Cheap flights from Indianapolis to San Diego from $69

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indianapolis to San Diego departing on 2/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
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Frontier Logo
1:29 pm - 11:59 pmIND-SAN
13h 30m1 stop
Frontier Logo
4:47 pm - 10:40 amSAN-IND
14h 53m2 stops
$251Frontier
Find Deal
Fri, Dec 12 - Thu, Dec 18
Frontier Logo
1:29 pm - 11:59 pmIND-SAN
13h 30m1 stop
Frontier Logo
4:47 pm - 10:40 amSAN-IND
14h 53m2 stops
$252Frontier
Find Deal
Fri, Dec 12 - Thu, Dec 18
Frontier Logo
1:29 pm - 11:59 pmIND-SAN
13h 30m1 stop
Frontier Logo
4:47 pm - 10:40 amSAN-IND
14h 53m2 stops
$253Frontier
Find Deal
Fri, Dec 12 - Thu, Dec 18
Frontier Logo
7:19 pm - 7:15 pmIND-SAN
26h 56m1 stop
Frontier Logo
4:47 pm - 7:53 pmSAN-IND
24h 06m1 stop
$254Frontier
Find Deal
Thu, Dec 11 - Sat, Dec 13
Frontier Logo
7:19 pm - 11:59 pmIND-SAN
7h 40m1 stop
Frontier Logo
6:25 am - 8:26 pmSAN-IND
11h 01m1 stop
$255Frontier
Find Deal
Thu, Dec 11 - Mon, Dec 15
Frontier Logo
7:19 pm - 11:59 pmIND-SAN
7h 40m1 stop
Frontier Logo
6:25 am - 8:26 pmSAN-IND
11h 01m1 stop
$256Frontier
Find Deal
Thu, Dec 11 - Mon, Dec 15
Multiple Airlines Logo
1:29 pm - 11:59 pmIND-SAN
13h 30m1 stop
Multiple Airlines Logo
6:34 am - 7:38 pmSAN-IND
34h 04m2 stops
$257Multiple Airlines
Find Deal
Fri, Dec 12 - Tue, Dec 16
Frontier Logo
7:19 pm - 11:59 pmIND-SAN
7h 40m1 stop
Frontier Logo
6:34 am - 7:53 pmSAN-IND
10h 19m1 stop
$258Frontier
Find Deal
Thu, Dec 11 - Sun, Dec 14
Frontier Logo
7:19 pm - 11:59 pmIND-SAN
7h 40m1 stop
Frontier Logo
6:34 am - 7:53 pmSAN-IND
10h 19m1 stop
$259Frontier
Find Deal
Thu, Dec 11 - Fri, Dec 12
Frontier Logo
7:19 pm - 11:59 pmIND-SAN
7h 40m1 stop
Frontier Logo
6:34 am - 7:53 pmSAN-IND
10h 19m1 stop
$260Frontier
Find Deal
Thu, Dec 11 - Sun, Dec 14

Frontier flights from Indianapolis to San Diego

Our best Frontier deals on Indianapolis to San Diego flight tickets
Frontier
Dec 12
IND1:29 pmIndianapolis
13h 30m
1 stop
SAN11:59 pmSan Diego
Dec 18
SAN4:47 pmSan Diego
14h 53m
2 stops
IND10:40 amIndianapolis
Frontier
Dec 12
IND1:29 pmIndianapolis
13h 30m
1 stop
SAN11:59 pmSan Diego
Dec 18
SAN4:47 pmSan Diego
14h 53m
2 stops
IND10:40 amIndianapolis
Frontier
Dec 12
IND1:29 pmIndianapolis
13h 30m
1 stop
SAN11:59 pmSan Diego
Dec 18
SAN4:47 pmSan Diego
14h 53m
2 stops
IND10:40 amIndianapolis

American Airlines flights from Indianapolis to San Diego

Our best American Airlines deals on Indianapolis to San Diego flight tickets
American Airlines
Feb 19
IND5:43 amIndianapolis
11h 25m
1 stop
SAN2:08 pmSan Diego
Feb 24
SAN12:05 pmSan Diego
8h 45m
1 stop
IND11:50 pmIndianapolis
American Airlines
Jan 16
IND6:18 pmIndianapolis
7h 08m
1 stop
SAN10:26 pmSan Diego
Jan 18
SAN9:21 amSan Diego
10h 33m
1 stop
IND10:54 pmIndianapolis

momondo Fare Finder

 
Customize your flight search to find flights from Indianapolis to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 26, 2025.
Use the filters below to find and compare flights from Indianapolis to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Fri 12/12

1:29 pm-11:59 pm

1 stop13h 30m

San Diego

Thu 12/18

4:47 pm-10:40 am

2 stops14h 53m

$251

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Fri 12/12

1:29 pm-11:59 pm

1 stop13h 30m

San Diego

Thu 12/18

4:47 pm-10:40 am

2 stops14h 53m

$252

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Fri 12/12

1:29 pm-11:59 pm

1 stop13h 30m

San Diego

Thu 12/18

4:47 pm-10:40 am

2 stops14h 53m

$253

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Thu 12/11

7:19 pm-7:15 pm

1 stop26h 56m

San Diego

Sat 12/13

4:47 pm-7:53 pm

1 stop24h 06m

$254

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Thu 12/11

7:19 pm-11:59 pm

1 stop7h 40m

San Diego

Mon 12/15

6:25 am-8:26 pm

1 stop11h 01m

$255

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Thu 12/11

7:19 pm-11:59 pm

1 stop7h 40m

San Diego

Mon 12/15

6:25 am-8:26 pm

1 stop11h 01m

$256

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Fri 12/12

1:29 pm-11:59 pm

1 stop13h 30m

San Diego

Tue 12/16

6:34 am-7:38 pm

2 stops34h 04m

$257

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Thu 12/11

7:19 pm-11:59 pm

1 stop7h 40m

San Diego

Sun 12/14

6:34 am-7:53 pm

1 stop10h 19m

$258

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Thu 12/11

7:19 pm-11:59 pm

1 stop7h 40m

San Diego

Fri 12/12

6:34 am-7:53 pm

1 stop10h 19m

$259

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Thu 12/11

7:19 pm-11:59 pm

1 stop7h 40m

San Diego

Sun 12/14

6:34 am-7:53 pm

1 stop10h 19m

$260

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Indianapolis to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of May, then departing from Indianapolis during the month September is also very affordable. Most momondo users find prices during this month for around $297.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Indianapolis to San Diego is on a Tuesday. Travelers who choose to depart for San Diego on a Tuesday will often find tickets for as low as $398. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $562. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is in the evening when flights can be purchased for as low as $337. Flights at noon are often more expensive with an average ticket price of $572.

What is the cheapest Indianapolis to San Diego flight route?

Fly from Indianapolis to San Diego for the best Indianapolis - San Diego flight prices

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Indianapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $349 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Indianapolis for as low as $309 on momondo.

What cabin class options are available on Indianapolis to San Diego flights?

There is only 1 cabin class available to choose from on Indianapolis to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Indianapolis to San Diego flight prices changed over time?

As of November 2025, prices for Indianapolis to San Diego flights are approximately 54% more expensive when compared to flights at the same time last year.

When to book flights from Indianapolis to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Indianapolis to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Indianapolis to San Diego (IND to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to San Diego

Best Price Found

$218

Fastest flight time

4h 30m

Direct flights

Mon, Tue, Wed, Fri, Sat and Sun

Airports in San Diego

1 airport
The best one-way flight to San Diego from Indianapolis in the past 72 hours is $218. The best round-trip flight deal from Indianapolis to San Diego found on momondo in the last 72 hours is $367.
The fastest flight from Indianapolis to San Diego takes 4h 30m
Direct flights go from Indianapolis to San Diego on Monday, Tuesday, Wednesday, Friday, Saturday and Sunday. The only airline offering direct flights is Southwest.
There is 1 airport near San Diego: San Diego (SAN)
  • How far is Indianapolis to San Diego by plane?

    The distance between Indianapolis and San Diego is about 1783.7 mi. By plane, this route typically takes 6h 04m.

  • When did momondo last update prices for flights from Indianapolis Airport to San Diego Airport?

    Prices for flights from Indianapolis Airport to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Indianapolis Airport to San Diego Airport?

  • How old do you have to be to fly from Indianapolis Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Indianapolis Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Indianapolis to San Diego?

  • What is the most popular airline from Indianapolis to San Diego?

Best airlines flying from Indianapolis to San Diego

Compare and see reviews for airlines that fly from Indianapolis to San Diego with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $130Free CancellationRating
5.8
3,099 reviews
Search Frontier flights
Spirit AirlinesPriceFrom $138Free CancellationRating
6.3
8,158 reviews
Search Spirit Airlines flights
DeltaPriceFrom $203Free CancellationRating
7.9
7,998 reviews
Search Delta flights
American AirlinesPriceFrom $216Free CancellationRating
7.2
11,038 reviews
Search American Airlines flights
United AirlinesPriceFrom $228Free CancellationRating
7.4
9,046 reviews
Search United Airlines flights
SouthwestPriceFrom $272Free CancellationRating
8.0
4,254 reviews
Search Southwest flights
  • Southwest Flights From Indianapolis to San Diego

    Southwest operates around 5 flights from Indianapolis to San Diego every week. The average price of these flights found in the last 72 hours has been $423, but momondo users have found Southwest deals from Indianapolis to San Diego from as low as $272 round-trip. Southwest has been scored 8.0/10 in 4,254 reviews.

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
Imperial Beach
La Mesa
Poway
Borrego Springs
San Ysidro
Lemon Grove
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to San Diego?

It is quick and easy to find Indianapolis to San Diego flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to San Diego that suits you.

Can I find flights from Indianapolis to San Diego with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Indianapolis to San Diego flights to just show those with flexible booking policies.

How can momondo help me find flights from Indianapolis to San Diego?

momondo helps you find the best flight between Indianapolis and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Indianapolis to San Diego right now. Can momondo alert me if prices change?

Price alerts on flights to San Diego from Indianapolis are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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1 adult
Fri 12/26
Fri 1/2

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