Cheap flights from Indianapolis to San Diego from $74

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indianapolis to San Diego departing on 4/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
8:27 pm - 12:02 am
IND
-
SAN
6h 35m
1 stop
Frontier Logo
6:25 am - 7:35 pm
SAN
-
IND
10h 10m
1 stop
$250Frontier
Sa, Apr 4 - Mo, Apr 6
Frontier Logo
8:27 pm - 12:05 am
IND
-
SAN
6h 38m
1 stop
Frontier Logo
12:00 pm - 7:32 pm
SAN
-
IND
28h 32m
1 stop
$251Frontier
Do, Apr 2 - Mi, Apr 8
Frontier Logo
8:33 pm - 12:08 am
IND
-
SAN
6h 35m
1 stop
Frontier Logo
2:08 pm - 12:54 pm
SAN
-
IND
19h 46m
1 stop
$252Frontier
Fr, Mrz 20 - Mi, Mrz 25
Frontier Logo
8:30 pm - 12:02 am
IND
-
SAN
30h 32m
1 stop
Frontier Logo
9:28 pm - 11:23 am
SAN
-
IND
34h 55m
2 stops
$253Frontier
Fr, Apr 3 - Sa, Apr 11
Frontier Logo
8:38 pm - 2:46 pm
IND
-
SAN
21h 08m
2 stops
Frontier Logo
6:25 am - 7:32 pm
SAN
-
IND
10h 07m
1 stop
$254Frontier
Mo, Mrz 30 - Sa, Apr 11
Frontier Logo
3:00 pm - 1:13 pm
IND
-
SAN
25h 13m
2 stops
Frontier Logo
6:25 am - 7:35 pm
SAN
-
IND
10h 10m
1 stop
$256Frontier
Mo, Mrz 30 - Mo, Apr 6
American Airlines Logo
7:43 pm - 11:33 pm
IND
-
SAN
6h 50m
1 stop
American Airlines Logo
10:40 pm - 10:19 am
SAN
-
IND
8h 39m
1 stop
$257American Airlines
Di, Apr 7 - So, Apr 12
Frontier Logo
8:30 pm - 12:02 am
IND
-
SAN
30h 32m
1 stop
Frontier Logo
6:25 am - 7:32 pm
SAN
-
IND
10h 07m
1 stop
$258Frontier
Fr, Apr 3 - Sa, Apr 11
Frontier Logo
8:38 pm - 2:46 pm
IND
-
SAN
21h 08m
2 stops
Frontier Logo
6:25 am - 7:32 pm
SAN
-
IND
10h 07m
1 stop
$259Frontier
Mo, Mrz 30 - Do, Apr 9
Frontier Logo
8:33 pm - 12:08 am
IND
-
SAN
6h 35m
1 stop
Frontier Logo
6:25 am - 7:42 pm
SAN
-
IND
10h 17m
1 stop
$260Frontier
Fr, Mrz 27 - Di, Apr 7

Frontier flights from Indianapolis to San Diego

Our best Frontier deals on Indianapolis to San Diego flight tickets
Frontier
Apr 4
IND8:27 pmIndianapolis
6h 35m
1 stop
SAN12:02 amSan Diego
Apr 6
SAN6:25 amSan Diego
10h 10m
1 stop
IND7:35 pmIndianapolis
$250
Frontier
Apr 2
IND8:27 pmIndianapolis
6h 38m
1 stop
SAN12:05 amSan Diego
Apr 8
SAN12:00 pmSan Diego
28h 32m
1 stop
IND7:32 pmIndianapolis
$251
Frontier
Mar 20
IND8:33 pmIndianapolis
6h 35m
1 stop
SAN12:08 amSan Diego
Mar 25
SAN2:08 pmSan Diego
19h 46m
1 stop
IND12:54 pmIndianapolis
$252

American Airlines flights from Indianapolis to San Diego

Our best American Airlines deals on Indianapolis to San Diego flight tickets
American Airlines
Apr 7
IND7:43 pmIndianapolis
6h 50m
1 stop
SAN11:33 pmSan Diego
Apr 12
SAN10:40 pmSan Diego
8h 39m
1 stop
IND10:19 amIndianapolis
$257
American Airlines
Apr 7
IND5:33 pmIndianapolis
9h 00m
1 stop
SAN11:33 pmSan Diego
Apr 12
SAN10:40 pmSan Diego
8h 39m
1 stop
IND10:19 amIndianapolis
$307
American Airlines
Mar 12
IND9:21 amIndianapolis
8h 02m
1 stop
SAN2:23 pmSan Diego
Mar 15
SAN10:35 pmSan Diego
7h 16m
1 stop
IND8:51 amIndianapolis
$368

momondo Fare Finder

 
Customize your flight search to find flights from Indianapolis to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated März 2, 2026.
Use the filters below to find and compare flights from Indianapolis to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Sa 4/4

8:27 pm-12:02 am

1 stop6h 35m

San Diego

Mo 4/6

6:25 am-7:35 pm

1 stop10h 10m

$250

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Do 4/2

8:27 pm-12:05 am

1 stop6h 38m

San Diego

Mi 4/8

12:00 pm-7:32 pm

1 stop28h 32m

$251

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Fr 3/20

8:33 pm-12:08 am

1 stop6h 35m

San Diego

Mi 3/25

2:08 pm-12:54 pm

1 stop19h 46m

$252

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Fr 4/3

8:30 pm-12:02 am

1 stop30h 32m

San Diego

Sa 4/11

9:28 pm-11:23 am

2 stops34h 55m

$253

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Mo 3/30

8:38 pm-2:46 pm

2 stops21h 08m

San Diego

Sa 4/11

6:25 am-7:32 pm

1 stop10h 07m

$254

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Mo 3/30

3:00 pm-1:13 pm

2 stops25h 13m

San Diego

Mo 4/6

6:25 am-7:35 pm

1 stop10h 10m

$256

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Di 4/7

7:43 pm-11:33 pm

1 stop6h 50m

San Diego

So 4/12

10:40 pm-10:19 am

1 stop8h 39m

$257

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Fr 4/3

8:30 pm-12:02 am

1 stop30h 32m

San Diego

Sa 4/11

6:25 am-7:32 pm

1 stop10h 07m

$258

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Mo 3/30

8:38 pm-2:46 pm

2 stops21h 08m

San Diego

Do 4/9

6:25 am-7:32 pm

1 stop10h 07m

$259

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Fr 3/27

8:33 pm-12:08 am

1 stop6h 35m

San Diego

Di 4/7

6:25 am-7:42 pm

1 stop10h 17m

$260

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Indianapolis to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of May, then departing from Indianapolis during the month September is also very affordable. Most momondo users find prices during this month for around $315.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Indianapolis to San Diego is on a Tuesday. Travelers who choose to depart for San Diego on a Tuesday will often find tickets for as low as $413. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $589. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is in the morning when flights can be purchased for as low as $449. Flights in the evening are often more expensive with an average ticket price of $593.

What is the cheapest Indianapolis to San Diego flight route?

Fly from Indianapolis to San Diego for the best Indianapolis - San Diego flight prices

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Indianapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $358 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Indianapolis for as low as $311 on momondo.

What cabin class options are available on Indianapolis to San Diego flights?

There is only 1 cabin class available to choose from on Indianapolis to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Indianapolis to San Diego flight prices changed over time?

As of March 2026, prices for Indianapolis to San Diego flights are approximately 47% more expensive when compared to flights at the same time last year.

When to book flights from Indianapolis to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Indianapolis to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Indianapolis to San Diego (IND to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to San Diego

Best Price Found

$232

Fastest flight time

4h 10m

Direct flights

Mon, Tue, Fri, Sat and Sun

Airports in San Diego

1 airport
The best one-way flight to San Diego from Indianapolis in the past 72 hours is $232. The best round-trip flight deal from Indianapolis to San Diego found on momondo in the last 72 hours is $402.
The fastest flight from Indianapolis to San Diego takes 4h 10m
Direct flights go from Indianapolis to San Diego on Monday, Tuesday, Friday, Saturday and Sunday. The only airline offering direct flights is Southwest.
There is 1 airport in San Diego. From Indianapolis there are direct flights to San Diego (SAN).
  • How far is Indianapolis to San Diego by plane?

    The distance between Indianapolis and San Diego is about 1783.7 mi. By plane, this route typically takes 4h 10m.

  • When did momondo last update prices for flights from Indianapolis Airport to San Diego Airport?

    Prices for flights from Indianapolis Airport to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Indianapolis Airport to San Diego Airport?

  • How old do you have to be to fly from Indianapolis Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Indianapolis Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Indianapolis to San Diego?

  • What is the most popular airline from Indianapolis to San Diego?

Best airlines flying from Indianapolis to San Diego

Compare and see reviews for airlines that fly from Indianapolis to San Diego with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $86Free CancellationRating
5.7
3,040 reviews
Search Frontier flights
Spirit AirlinesPriceFrom $99Free CancellationRating
6.3
8,487 reviews
Search Spirit Airlines flights
DeltaPriceFrom $203Free CancellationRating
7.9
8,237 reviews
Search Delta flights
United AirlinesPriceFrom $204Free CancellationRating
7.4
9,376 reviews
Search United Airlines flights
American AirlinesPriceFrom $208Free CancellationRating
7.1
11,369 reviews
Search American Airlines flights
SouthwestPriceFrom $275Free CancellationRating
8.0
4,306 reviews
Search Southwest flights
  • Southwest Flights From Indianapolis to San Diego

    Southwest operates around 1 flight from Indianapolis to San Diego every week. The average price of these flights found in the last 72 hours has been $425, but momondo users have found Southwest deals from Indianapolis to San Diego from as low as $275 round-trip. Southwest has been scored 8.0/10 in 4,306 reviews.

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
Poway
National City
Imperial Beach
San Ysidro
Borrego Springs
La Mesa
Alpine
Lemon Grove
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to San Diego?

It is quick and easy to find Indianapolis to San Diego flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to San Diego that suits you.

Can I find flights from Indianapolis to San Diego with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Indianapolis to San Diego flights to just show those with flexible booking policies.

How can momondo help me find flights from Indianapolis to San Diego?

momondo helps you find the best flight between Indianapolis and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Indianapolis to San Diego right now. Can momondo alert me if prices change?

Price alerts on flights to San Diego from Indianapolis are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your San Diego trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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1 adult
Mi 4/1
Mi 4/8

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