What is the cheapest airline that flies from Lambert-St Louis to San Diego?

Frontier, Southwest, and Alaska Airlines are the most popular carriers operating from Lambert-St Louis to San Diego

How many flights depart from St. Louis to San Diego on average per week?

The number of flights available between St. Louis and San Diego is 6 per week as of November 2025. The most frequent departure day is Mon, with 33% of weekly flights leaving on this day.

What airlines fly to San Diego?

Southwest, American Airlines and Frontier are the top three most popular airlines that fly to San Diego from St. Louis according to our data. Southwest is the first choice among our users, with 45% of people opting to fly with this airline when traveling to San Diego. Keep in mind that there are 5 different airlines that fly to San Diego on a routine basis, so you have a few additional options to choose from.

Which airport is the most popular layover for flights between St. Louis and San Diego?

Phoenix (PHX) was the most common stop: 52% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport has the shortest connection time from St. Louis to San Diego?

Chicago (ORD) has the shortest average layover time for this route: 0h 58m.

Which layover airport has the shortest travel time from St. Louis to San Diego?

Flights connecting via Las Vegas (LAS) have the shortest average one-way travel time: 6h 00m.

Which layover airport offers the lowest fares from St. Louis to San Diego?

Flights via Denver (DEN) offer the lowest average round-trip price of $273.

When did momondo last update prices for flights from Lambert-St Louis Airport to San Diego Airport?

Prices for flights from Lambert-St Louis Airport to San Diego Airport are updated daily.

How many operators does momondo search for flights from Lambert-St Louis Airport to San Diego Airport?

The number of operators available for flights from Lambert-St Louis Airport to San Diego Airport is 5 as of November 2025.

How old do you have to be to fly from Lambert-St Louis Airport to San Diego Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to San Diego Airport.

What documentation or ID do you need to fly to San Diego Airport?

The travel and health documents you'll need for your trip to San Diego Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Diego Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$61 Cheap Flights from St. Louis to San Diego in 2025/26

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Find the cheapest flights from St. Louis to San Diego

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One-way

Last minute

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Cheap round-trip flights

Enter your travel dates to find the best prices.

7:43 pm - 12:55 pmSTL-SAN

19h 12m1 stop

6:25 am - 10:02 amSAN-STL

25h 37m1 stop

$188Frontier

Find Deal

vie., ene. 16 - mar., ene. 20

7:43 pm - 10:46 pmSTL-SAN

29h 03m1 stop

4:22 pm - 10:02 amSAN-STL

15h 40m1 stop

$191Frontier

Find Deal

lun., ene. 19 - jue., ene. 22

10:10 pm - 12:11 pmSTL-SAN

16h 01m1 stop

1:43 pm - 8:53 pmSAN-STL

29h 10m2 stops

$193Frontier

Find Deal

lun., dic. 22 - mié., ene. 14

3:30 pm - 7:15 pmSTL-SAN

29h 45m2 stops

3:47 pm - 12:12 pmSAN-STL

18h 25m1 stop

$196Frontier

Find Deal

jue., dic. 4 - jue., dic. 11

2:50 pm - 8:58 pmSTL-SAN

8h 08m1 stop

8:00 am - 7:41 pmSAN-STL

9h 41m1 stop

$206Multiple Airlines

Find Deal

mar., ene. 27 - vie., ene. 30

7:43 pm - 11:59 pmSTL-SAN

6h 16m1 stop

6:15 am - 11:59 pmSAN-STL

15h 44m1 stop

$246Multiple Airlines

Find Deal

vie., dic. 12 - lun., dic. 15

7:00 am - 3:06 pmSTL-SAN

10h 06m1 stop

8:59 pm - 2:27 pmSAN-STL

15h 28m1 stop

$252Alaska Airlines

Find Deal

jue., dic. 4 - lun., dic. 8

5:00 pm - 11:48 pmSTL-SAN

8h 48m1 stop

6:15 am - 2:48 pmSAN-STL

6h 33m1 stop

$253Delta

Find Deal

lun., ene. 26 - mié., feb. 4

6:10 am - 1:50 pmSTL-SAN

9h 40m1 stop

6:50 am - 11:25 pmSAN-STL

14h 35m2 stops

$264Delta

Find Deal

mar., ene. 27 - mar., feb. 3

2:50 pm - 9:32 amSTL-SAN

20h 42m2 stops

7:03 pm - 1:54 pmSAN-STL

16h 51m1 stop

$273Alaska Airlines

Find Deal

lun., feb. 2 - jue., feb. 5

Alaska Airlines flights from St. Louis to San Diego

Our best Alaska Airlines deals on St. Louis to San Diego flight tickets

Alaska Airlines

Dec 4

STL7:00 amLambert-St Louis

10h 06m

1 stop

SAN3:06 pmSan Diego

Dec 8

SAN8:59 pmSan Diego

15h 28m

1 stop

STL2:27 pmLambert-St Louis

$252

Find similar

Alaska Airlines

Feb 2

STL2:50 pmLambert-St Louis

20h 42m

2 stops

SAN9:32 amSan Diego

Feb 5

SAN7:03 pmSan Diego

16h 51m

1 stop

STL1:54 pmLambert-St Louis

$273

Find similar

Alaska Airlines

Nov 14

STL7:00 amLambert-St Louis

11h 20m

2 stops

SAN4:20 pmSan Diego

Nov 18

SAN4:30 pmSan Diego

20h 48m

2 stops

STL3:18 pmLambert-St Louis

$721

Find similar

Delta flights from St. Louis to San Diego

Our best Delta deals on St. Louis to San Diego flight tickets

Delta

Jan 26

STL5:00 pmLambert-St Louis

8h 48m

1 stop

SAN11:48 pmSan Diego

Feb 4

SAN6:15 amSan Diego

6h 33m

1 stop

STL2:48 pmLambert-St Louis

$253

Find similar

Delta

Jan 27

STL6:10 amLambert-St Louis

9h 40m

1 stop

SAN1:50 pmSan Diego

Feb 3

SAN6:50 amSan Diego

14h 35m

2 stops

STL11:25 pmLambert-St Louis

$264

Find similar

Delta

Jan 31

STL7:00 amLambert-St Louis

11h 30m

2 stops

SAN4:30 pmSan Diego

Feb 4

SAN11:00 amSan Diego

10h 25m

2 stops

STL11:25 pmLambert-St Louis

$276

Find similar

Fly from

Fly to

Route

Depart

Return

Price

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

vie. 1/16

7:43 pm-12:55 pm

1 stop19h 12m

San Diego

mar. 1/20

6:25 am-10:02 am

1 stop25h 37m

$188

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

lun. 1/19

7:43 pm-10:46 pm

1 stop29h 03m

San Diego

jue. 1/22

4:22 pm-10:02 am

1 stop15h 40m

$191

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

lun. 12/22

10:10 pm-12:11 pm

1 stop16h 01m

San Diego

mié. 1/14

1:43 pm-8:53 pm

2 stops29h 10m

$193

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

jue. 12/4

3:30 pm-7:15 pm

2 stops29h 45m

San Diego

jue. 12/11

3:47 pm-12:12 pm

1 stop18h 25m

$196

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

mar. 1/27

2:50 pm-8:58 pm

1 stop8h 08m

San Diego

vie. 1/30

8:00 am-7:41 pm

1 stop9h 41m

$206

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

vie. 12/12

7:43 pm-11:59 pm

1 stop6h 16m

San Diego

lun. 12/15

6:15 am-11:59 pm

1 stop15h 44m

$246

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

jue. 12/4

7:00 am-3:06 pm

1 stop10h 06m

San Diego

lun. 12/8

8:59 pm-2:27 pm

1 stop15h 28m

$252

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

lun. 1/26

5:00 pm-11:48 pm

1 stop8h 48m

San Diego

mié. 2/4

6:15 am-2:48 pm

1 stop6h 33m

$253

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

mar. 1/27

6:10 am-1:50 pm

1 stop9h 40m

San Diego

mar. 2/3

6:50 am-11:25 pm

2 stops14h 35m

$264

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

lun. 2/2

2:50 pm-9:32 am

2 stops20h 42m

San Diego

jue. 2/5

7:03 pm-1:54 pm

1 stop16h 51m

$273

Flights are sorted by cheapest round-trip flights first.

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How to get the cheapest flight ticket from St. Louis to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

Other information

What is the typical price of a round-trip flight between St. Louis and San Diego?

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of January, then departing from St. Louis during the month September is also very affordable. Most momondo users find prices during this month for around $331.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from St. Louis to San Diego is on a Tuesday. Travelers who choose to depart for San Diego on a Tuesday will often find tickets for as low as $436. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $616. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is in the afternoon when flights can be purchased for as low as $455. Flights at noon are often more expensive with an average ticket price of $601.

What is the cheapest Lambert-St Louis to San Diego flight route?

Fly from Lambert-St Louis to San Diego for the best Lambert-St Louis - San Diego flight prices

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from St. Louis when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $361 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from St. Louis for as low as $315 on momondo.

What cabin class options are available on Lambert-St Louis to San Diego flights?

There is only 1 cabin class available to choose from on Lambert-St Louis to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have St. Louis to San Diego flight prices changed over time?

As of November 2025, prices for St. Louis to San Diego flights are approximately 30% cheaper when compared to flights at the same time last year.

When to book flights from St. Louis to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from St. Louis to San Diego according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap St. Louis to San Diego (STL to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to San Diego

Best Price Found	$166
Fastest flight time	3h 55m
Direct flights	Every day
Airports in San Diego	1 airport

The best one-way flight to San Diego from St. Louis in the past 72 hours is $166. The best round-trip flight deal from St. Louis to San Diego found on momondo in the last 72 hours is $362.

The fastest flight from St. Louis to San Diego takes 3h 55m

Direct flights go from St. Louis to San Diego every day.

There is 1 airport near San Diego: San Diego (SAN)

Search flight deals

How far is Lambert-St Louis to San Diego by plane?
There are 1560.0 mi between Lambert-St Louis and San Diego. By plane, this route typically takes 6h 05m.
When did momondo last update prices for flights from Lambert-St Louis Airport to San Diego Airport?
Prices for flights from Lambert-St Louis Airport to San Diego Airport are updated daily.
How many operators does momondo search for flights from Lambert-St Louis Airport to San Diego Airport?
The number of operators available for flights from Lambert-St Louis Airport to San Diego Airport is 5 as of November 2025.
How old do you have to be to fly from Lambert-St Louis Airport to San Diego Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to San Diego Airport.
What documentation or ID do you need to fly to San Diego Airport?
The travel and health documents you'll need for your trip to San Diego Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Diego Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from St. Louis to San Diego?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from St. Louis to San Diego is Boeing 737 MAX 8 (58.40% of total bookings). The next most popular plane models are Boeing 737-800 Passenger/BBJ2 (winglets) (31.20%), Airbus A319 (2.40%), and Boeing 737-700 Passenger/BBJ1 (winglets) (2.40%).
What is the most popular airline from St. Louis to San Diego?
Based on momondo bookings for flights between St. Louis and San Diego, the leading airline is Southwest, making up 42% of the total bookings. Other popular airlines include American Airlines with 26%, Frontier with 12%, and Delta with 11%.

Best airlines flying from St. Louis to San Diego

Compare and see reviews for airlines that fly from St. Louis to San Diego with momondo

Airline	Rating	Free Cancellation	Price
Frontier	PriceFrom $88	Free Cancellation	Rating 5.8 3,117 reviews	Search Frontier flights
United Airlines	PriceFrom $182	Free Cancellation	Rating 7.4 9,002 reviews	Search United Airlines flights
American Airlines	PriceFrom $226	Free Cancellation	Rating 7.2 11,040 reviews	Search American Airlines flights
Delta	PriceFrom $256	Free Cancellation	Rating 7.9 8,003 reviews	Search Delta flights
Southwest	PriceFrom $306	Free Cancellation	Rating 8.0 4,239 reviews	Search Southwest flights

Southwest Flights From St. Louis to San Diego
The lowest priced Southwest flight from St. Louis to San Diego from the last 72 hours was $306. Generally, Southwest has 6 flights on this route every week with an average price of $478. Southwest is rated 8.0/10 by our users.

Coronado

Chula Vista

El Cajon

Julian

National City

Imperial Beach

La Mesa

Poway

Borrego Springs

San Ysidro

Lemon Grove

Alpine

Santee

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to San Diego?

Finding the right flight to San Diego from St. Louis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Diego quick and easy, saving you time and money.

Can I find flights from St. Louis to San Diego with flexible booking policies on momondo?

Flights from St. Louis to San Diego with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from St. Louis to San Diego?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from St. Louis to San Diego.

I’m not ready to book a flight from St. Louis to San Diego right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Diego from St. Louis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your San Diego trip

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Cheap flights from St. Louis to San Diego from $61

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to San Diego departing on 12/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Alaska Airlines flights from St. Louis to San Diego

Our best Alaska Airlines deals on St. Louis to San Diego flight tickets

Delta flights from St. Louis to San Diego

Our best Delta deals on St. Louis to San Diego flight tickets

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How to get the cheapest flight ticket from St. Louis to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between St. Louis and San Diego?

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of January, then departing from St. Louis during the month September is also very affordable. Most momondo users find prices during this month for around $331.

What is the cheapest day to depart on your flight to San Diego?

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is in the afternoon when flights can be purchased for as low as $455. Flights at noon are often more expensive with an average ticket price of $601.

What is the cheapest Lambert-St Louis to San Diego flight route?

Fly from Lambert-St Louis to San Diego for the best Lambert-St Louis - San Diego flight prices

How far in advance should I book a flight to San Diego?

What cabin class options are available on Lambert-St Louis to San Diego flights?

There is only 1 cabin class available to choose from on Lambert-St Louis to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have St. Louis to San Diego flight prices changed over time?

As of November 2025, prices for St. Louis to San Diego flights are approximately 30% cheaper when compared to flights at the same time last year.

What is the cheapest airline that flies from Lambert-St Louis to San Diego?

Frontier, Southwest, and Alaska Airlines are the most popular carriers operating from Lambert-St Louis to San Diego

What airlines fly to San Diego?

Which airport is the most popular layover for flights between St. Louis and San Diego?

Phoenix (PHX) was the most common stop: 52% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from St. Louis to San Diego?

Flights via Denver (DEN) offer the lowest average round-trip price of $273.

Which layover airport has the shortest travel time from St. Louis to San Diego?

Flights connecting via Las Vegas (LAS) have the shortest average one-way travel time: 6h 00m.

Which layover airport has the shortest connection time from St. Louis to San Diego?

Chicago (ORD) has the shortest average layover time for this route: 0h 58m.

How many flights depart from St. Louis to San Diego on average per week?

The number of flights available between St. Louis and San Diego is 6 per week as of November 2025. The most frequent departure day is Mon, with 33% of weekly flights leaving on this day.

When to book flights from St. Louis to San Diego

Cheap St. Louis to San Diego (STL to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to San Diego

Best Price Found

Fastest flight time

Direct flights

Airports in San Diego

How far is Lambert-St Louis to San Diego by plane?

When did momondo last update prices for flights from Lambert-St Louis Airport to San Diego Airport?

How many operators does momondo search for flights from Lambert-St Louis Airport to San Diego Airport?

How old do you have to be to fly from Lambert-St Louis Airport to San Diego Airport?

What documentation or ID do you need to fly to San Diego Airport?

What is the most popular plane model from St. Louis to San Diego?

What is the most popular airline from St. Louis to San Diego?

Best airlines flying from St. Louis to San Diego

Compare and see reviews for airlines that fly from St. Louis to San Diego with momondo

Southwest Flights From St. Louis to San Diego

Traveling to a place near San Diego?

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to San Diego?

Can I find flights from St. Louis to San Diego with flexible booking policies on momondo?

How can momondo help me find flights from St. Louis to San Diego?

I’m not ready to book a flight from St. Louis to San Diego right now. Can momondo alert me if prices change?

An easier way to manage your San Diego trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing California