How many flights depart from St. Louis to San Diego on average per week?

The number of flights available between St. Louis and San Diego is 5 per week as of September 2025. The most frequent departure day is Mon, with 20% of weekly flights leaving on this day.

Which layover airport has the shortest travel time from St. Louis to San Diego?

Flights connecting via Las Vegas (LAS) have the shortest average one-way travel time: 6h 00m.

Which layover airport offers the lowest fares from St. Louis to San Diego?

Flights via Denver (DEN) offer the lowest average round-trip price of $292.

What is the cheapest airline that flies from Lambert-St Louis to San Diego?

Frontier, United Airlines, and Delta are the most popular carriers operating from Lambert-St Louis to San Diego

Which airport is the most popular layover for flights between St. Louis and San Diego?

Phoenix (PHX) was the most common stop: 52% of momondo users choosing 1-stop flights on this route connected there.

What airlines fly to San Diego?

Southwest, American Airlines and Frontier are the top three most popular airlines that fly to San Diego from St. Louis according to our data. Southwest is the first choice among our users, with 40% of people opting to fly with this airline when traveling to San Diego. Keep in mind that there are 5 different airlines that fly to San Diego on a routine basis, so you have a few additional options to choose from.

Which layover airport has the shortest connection time from St. Louis to San Diego?

Chicago (ORD) has the shortest average layover time for this route: 0h 58m.

When did momondo last update prices for flights from Lambert-St Louis Airport to San Diego Airport?

Prices for flights from Lambert-St Louis Airport to San Diego Airport are updated daily.

How many operators does momondo search for flights from Lambert-St Louis Airport to San Diego Airport?

The number of operators available for flights from Lambert-St Louis Airport to San Diego Airport is 5 as of September 2025.

How old do you have to be to fly from Lambert-St Louis Airport to San Diego Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to San Diego Airport.

What documentation or ID do you need to fly to San Diego Airport?

The travel and health documents you'll need for your trip to San Diego Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Diego Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$72 Cheap Flights from St. Louis to San Diego in 2025/26

Q: What is the typical price of a round-trip flight between St. Louis and San Diego?

Prices are currently low for flights on this route. Typical prices usually range from $256 to $464. The lowest price recently found on this route was $143.

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from St. Louis to San Diego

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

7:52 pm - 11:50 pmSTL-SAN

5h 58m1 stop

8:00 am - 3:56 pmSAN-STL

5h 56m1 stop

$143Frontier

Find Deal

mié., oct. 22 - sáb., oct. 25

7:52 pm - 11:50 pmSTL-SAN

5h 58m1 stop

7:23 pm - 9:32 amSAN-STL

12h 09m1 stop

$144Frontier

Find Deal

vie., oct. 24 - dom., oct. 26

9:59 pm - 8:51 pmSTL-SAN

24h 52m1 stop

4:06 pm - 9:04 pmSAN-STL

26h 58m1 stop

$145Frontier

Find Deal

vie., oct. 10 - dom., oct. 12

8:40 pm - 11:17 amSTL-SAN

16h 37m1 stop

6:41 am - 10:07 amSAN-STL

25h 26m1 stop

$146Frontier

Find Deal

mié., oct. 29 - sáb., nov. 1

7:43 pm - 8:05 amSTL-SAN

14h 22m1 stop

6:25 am - 10:02 amSAN-STL

25h 37m1 stop

$154Frontier

Find Deal

mié., dic. 3 - dom., dic. 7

10:17 am - 6:28 pmSTL-SAN

10h 11m1 stop

3:59 pm - 11:43 amSAN-STL

17h 44m1 stop

$156Frontier

Find Deal

jue., oct. 16 - jue., oct. 23

7:55 pm - 11:53 pmSTL-SAN

5h 58m1 stop

9:03 pm - 9:06 amSAN-STL

10h 03m1 stop

$157Frontier

Find Deal

vie., sep. 26 - jue., oct. 2

6:00 am - 10:48 amSTL-SAN

6h 48m1 stop

10:23 pm - 9:32 amSAN-STL

9h 09m1 stop

$183American Airlines

Find Deal

mié., dic. 3 - lun., dic. 8

1:35 pm - 5:28 pmSTL-SAN

5h 53m1 stop

11:02 am - 9:54 pmSAN-STL

8h 52m2 stops

$188United Airlines

Find Deal

mar., nov. 4 - jue., nov. 13

7:43 pm - 1:30 pmSTL-SAN

19h 47m1 stop

12:38 pm - 1:53 pmSAN-STL

23h 15m2 stops

$228Multiple Airlines

Find Deal

lun., dic. 8 - vie., dic. 12

Frontier flights from St. Louis to San Diego

Our best Frontier deals on St. Louis to San Diego flight tickets

Frontier

Oct 22

STL7:52 pmLambert-St Louis

5h 58m

1 stop

SAN11:50 pmSan Diego

Oct 25

SAN8:00 amSan Diego

5h 56m

1 stop

STL3:56 pmLambert-St Louis

$143

Find similar

Frontier

Sep 25

STL10:49 amLambert-St Louis

8h 53m

1 stop

SAN5:42 pmSan Diego

Sep 28

SAN9:03 pmSan Diego

10h 03m

1 stop

STL9:06 amLambert-St Louis

$144

Find similar

Frontier

Oct 10

STL9:59 pmLambert-St Louis

24h 52m

1 stop

SAN8:51 pmSan Diego

Oct 12

SAN4:06 pmSan Diego

26h 58m

1 stop

STL9:04 pmLambert-St Louis

$145

Find similar

Fly from

Fly to

Route

Depart

Return

Price

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

mié. 10/22

7:52 pm-11:50 pm

1 stop5h 58m

San Diego

sáb. 10/25

8:00 am-3:56 pm

1 stop5h 56m

$143

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

vie. 10/24

7:52 pm-11:50 pm

1 stop5h 58m

San Diego

dom. 10/26

7:23 pm-9:32 am

1 stop12h 09m

$144

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

vie. 10/10

9:59 pm-8:51 pm

1 stop24h 52m

San Diego

dom. 10/12

4:06 pm-9:04 pm

1 stop26h 58m

$145

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

mié. 10/29

8:40 pm-11:17 am

1 stop16h 37m

San Diego

sáb. 11/1

6:41 am-10:07 am

1 stop25h 26m

$146

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

mié. 12/3

7:43 pm-8:05 am

1 stop14h 22m

San Diego

dom. 12/7

6:25 am-10:02 am

1 stop25h 37m

$154

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

jue. 10/16

10:17 am-6:28 pm

1 stop10h 11m

San Diego

jue. 10/23

3:59 pm-11:43 am

1 stop17h 44m

$156

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

vie. 9/26

7:55 pm-11:53 pm

1 stop5h 58m

San Diego

jue. 10/2

9:03 pm-9:06 am

1 stop10h 03m

$157

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

mié. 12/3

6:00 am-10:48 am

1 stop6h 48m

San Diego

lun. 12/8

10:23 pm-9:32 am

1 stop9h 09m

$183

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

mar. 11/4

1:35 pm-5:28 pm

1 stop5h 53m

San Diego

jue. 11/13

11:02 am-9:54 pm

2 stops8h 52m

$188

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

lun. 12/8

7:43 pm-1:30 pm

1 stop19h 47m

San Diego

vie. 12/12

12:38 pm-1:53 pm

2 stops23h 15m

$228

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from St. Louis to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

Other information

What is the typical price of a round-trip flight between St. Louis and San Diego?

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of January, then departing from St. Louis during the month September is also very affordable. Most momondo users find prices during this month for around $314.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from St. Louis to San Diego is on a Tuesday. Travelers who choose to depart for San Diego on a Tuesday will often find tickets for as low as $449. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $626. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is in the afternoon when flights can be purchased for as low as $484. Flights at noon are often more expensive with an average ticket price of $601.

What is the cheapest Lambert-St Louis to San Diego flight route?

Fly from Lambert-St Louis to San Diego for the best Lambert-St Louis - San Diego flight prices

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from St. Louis when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $359 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from St. Louis for as low as $302 on momondo.

What cabin class options are available on Lambert-St Louis to San Diego flights?

There is only 1 cabin class available to choose from on Lambert-St Louis to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have St. Louis to San Diego flight prices changed over time?

As of September 2025, prices for St. Louis to San Diego flights are approximately 83% more expensive when compared to flights at the same time last year.

When to book flights from St. Louis to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from St. Louis to San Diego according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap St. Louis to San Diego (STL to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to San Diego

Best Price Found	$166
Fastest flight time	3h 45m
Direct flights	Every day
Airports in San Diego	1 airport

The best one-way flight to San Diego from St. Louis in the past 72 hours is $166. The best round-trip flight deal from St. Louis to San Diego found on momondo in the last 72 hours is $379.

The fastest flight from St. Louis to San Diego takes 3h 45m

Direct flights go from St. Louis to San Diego every day.

There is 1 airport near San Diego: San Diego (SAN)

Search flight deals

How far is Lambert-St Louis to San Diego by plane?
There are 1560.0 mi between Lambert-St Louis and San Diego. By plane, this route typically takes 5h 53m.
When did momondo last update prices for flights from Lambert-St Louis Airport to San Diego Airport?
Prices for flights from Lambert-St Louis Airport to San Diego Airport are updated daily.
How many operators does momondo search for flights from Lambert-St Louis Airport to San Diego Airport?
The number of operators available for flights from Lambert-St Louis Airport to San Diego Airport is 5 as of September 2025.
How old do you have to be to fly from Lambert-St Louis Airport to San Diego Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to San Diego Airport.
What documentation or ID do you need to fly to San Diego Airport?
The travel and health documents you'll need for your trip to San Diego Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Diego Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from St. Louis to San Diego?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from St. Louis to San Diego is Boeing 737 MAX 8 (56.16% of total bookings). The next most popular plane models are Boeing 737-800 Passenger/BBJ2 (winglets) (24.66%), Boeing 737-700 Passenger/BBJ1 (winglets) (9.59%), and Airbus A319 (4.11%).
What is the most popular airline from St. Louis to San Diego?
Based on momondo bookings for flights between St. Louis and San Diego, the leading airline is Southwest, making up 38% of the total bookings. Other popular airlines include American Airlines with 28%, Delta with 12%, and Frontier with 12%.

Best airlines flying from St. Louis to San Diego

Compare and see reviews for airlines that fly from St. Louis to San Diego with momondo

Airline	Rating	Free Cancellation	Price
Frontier	PriceFrom $108	Free Cancellation	Rating 5.8 3,173 reviews	Search Frontier flights
American Airlines	PriceFrom $234	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights
Delta	PriceFrom $256	Free Cancellation	Rating 7.9 7,961 reviews	Search Delta flights
United Airlines	PriceFrom $266	Free Cancellation	Rating 7.4 8,926 reviews	Search United Airlines flights
Southwest	PriceFrom $312	Free Cancellation	Rating 8.0 4,242 reviews	Search Southwest flights

Southwest Flights From St. Louis to San Diego
The lowest priced Southwest flight from St. Louis to San Diego from the last 72 hours was $312. Generally, Southwest has 5 flights on this route every week with an average price of $493. Southwest is rated 8.0/10 by our users.

Coronado

Chula Vista

El Cajon

Julian

La Mesa

National City

Poway

Imperial Beach

San Ysidro

Borrego Springs

Lemon Grove

Alpine

Santee

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to San Diego?

Finding the right flight to San Diego from St. Louis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Diego quick and easy, saving you time and money.

Can I find flights from St. Louis to San Diego with flexible booking policies on momondo?

Flights from St. Louis to San Diego with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from St. Louis to San Diego?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from St. Louis to San Diego.

I’m not ready to book a flight from St. Louis to San Diego right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Diego from St. Louis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your San Diego trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

1 adult

vie. 10/17

vie. 10/24

Email me momondo's favorite deals

By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States

Airports servicing California

Popular cities in the United States

Flights to New Yorkfrom $49

Flights to Los Angelesfrom $49

Flights to Miamifrom $49

Flights to Chicagofrom $49

Flights to Orlandofrom $60

Flights to Las Vegasfrom $48

Flights to San Franciscofrom $53

Flights to Washington, D.C.from $49

Flights to Bostonfrom $62

Flights to Atlantafrom $51

Flights to Dallasfrom $68

Flights to Seattlefrom $69

Cheap flights from St. Louis to San Diego from $72

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to San Diego departing on 10/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from St. Louis to San Diego

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Cheap direct flights

Frontier flights from St. Louis to San Diego

Our best Frontier deals on St. Louis to San Diego flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from St. Louis to San Diego that are best for you.

See travel insights to San Diego from

How to get the cheapest flight ticket from St. Louis to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between St. Louis and San Diego?

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of January, then departing from St. Louis during the month September is also very affordable. Most momondo users find prices during this month for around $314.

What is the cheapest day to depart on your flight to San Diego?

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is in the afternoon when flights can be purchased for as low as $484. Flights at noon are often more expensive with an average ticket price of $601.

What is the cheapest Lambert-St Louis to San Diego flight route?

Fly from Lambert-St Louis to San Diego for the best Lambert-St Louis - San Diego flight prices

How far in advance should I book a flight to San Diego?

What cabin class options are available on Lambert-St Louis to San Diego flights?

There is only 1 cabin class available to choose from on Lambert-St Louis to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have St. Louis to San Diego flight prices changed over time?

As of September 2025, prices for St. Louis to San Diego flights are approximately 83% more expensive when compared to flights at the same time last year.

What is the cheapest airline that flies from Lambert-St Louis to San Diego?

Frontier, United Airlines, and Delta are the most popular carriers operating from Lambert-St Louis to San Diego

What airlines fly to San Diego?

Which airport is the most popular layover for flights between St. Louis and San Diego?

Phoenix (PHX) was the most common stop: 52% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from St. Louis to San Diego?

Flights via Denver (DEN) offer the lowest average round-trip price of $292.

Which layover airport has the shortest travel time from St. Louis to San Diego?

Flights connecting via Las Vegas (LAS) have the shortest average one-way travel time: 6h 00m.

Which layover airport has the shortest connection time from St. Louis to San Diego?

Chicago (ORD) has the shortest average layover time for this route: 0h 58m.

How many flights depart from St. Louis to San Diego on average per week?

The number of flights available between St. Louis and San Diego is 5 per week as of September 2025. The most frequent departure day is Mon, with 20% of weekly flights leaving on this day.

When to book flights from St. Louis to San Diego

Cheap St. Louis to San Diego (STL to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to San Diego

Best Price Found

Fastest flight time

Direct flights

Airports in San Diego

How far is Lambert-St Louis to San Diego by plane?

When did momondo last update prices for flights from Lambert-St Louis Airport to San Diego Airport?

How many operators does momondo search for flights from Lambert-St Louis Airport to San Diego Airport?

How old do you have to be to fly from Lambert-St Louis Airport to San Diego Airport?

What documentation or ID do you need to fly to San Diego Airport?

What is the most popular plane model from St. Louis to San Diego?

What is the most popular airline from St. Louis to San Diego?

Best airlines flying from St. Louis to San Diego

Compare and see reviews for airlines that fly from St. Louis to San Diego with momondo

Southwest Flights From St. Louis to San Diego

Traveling to a place near San Diego?

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to San Diego?

Can I find flights from St. Louis to San Diego with flexible booking policies on momondo?

How can momondo help me find flights from St. Louis to San Diego?

I’m not ready to book a flight from St. Louis to San Diego right now. Can momondo alert me if prices change?

An easier way to manage your San Diego trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing California