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Cheap flights from St. Louis to San Diego from $55

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to San Diego departing on 3/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from St. Louis to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
8:00 am - 2:29 pm
STL
-
SAN
8h 29m
1 stop
American Airlines Logo
10:35 pm - 10:13 am
SAN
-
STL
9h 38m
1 stop
$287American Airlines
Fri, Feb 27 - Fri, Mar 6
Frontier Logo
1:59 pm - 12:08 am
STL
-
SAN
12h 09m
1 stop
Frontier Logo
9:58 pm - 11:19 am
SAN
-
STL
11h 21m
1 stop
$289Frontier
Fri, Feb 27 - Fri, Mar 6
Frontier Logo
11:21 am - 12:11 am
STL
-
SAN
38h 50m
2 stops
Frontier Logo
12:36 pm - 7:12 pm
SAN
-
STL
28h 36m
1 stop
$290Frontier
Sun, Apr 26 - Sun, May 3
Frontier Logo
3:02 pm - 12:01 am
STL
-
SAN
10h 59m
2 stops
Frontier Logo
6:25 am - 7:12 pm
SAN
-
STL
10h 47m
1 stop
$291Frontier
Fri, Apr 17 - Mon, Apr 27
Frontier Logo
1:00 pm - 1:13 pm
STL
-
SAN
26h 13m
1 stop
Frontier Logo
9:18 pm - 9:49 am
SAN
-
STL
10h 31m
1 stop
$292Frontier
Tue, Mar 17 - Sun, Mar 22
Frontier Logo
1:54 pm - 12:08 am
STL
-
SAN
12h 14m
1 stop
Frontier Logo
3:16 pm - 9:49 am
SAN
-
STL
16h 33m
2 stops
$293Frontier
Mon, Feb 16 - Tue, Mar 10
Frontier Logo
8:12 pm - 11:08 pm
STL
-
SAN
28h 56m
1 stop
Frontier Logo
9:58 pm - 9:49 am
SAN
-
STL
9h 51m
2 stops
$297Frontier
Sat, Mar 7 - Fri, Mar 20
Frontier Logo
8:12 pm - 12:01 am
STL
-
SAN
5h 49m
1 stop
Frontier Logo
6:25 am - 7:12 pm
SAN
-
STL
10h 47m
1 stop
$300Frontier
Fri, Apr 17 - Sun, Apr 19
Frontier Logo
8:12 pm - 7:12 pm
STL
-
SAN
25h 00m
2 stops
Frontier Logo
8:39 pm - 11:19 am
SAN
-
STL
12h 40m
1 stop
$301Frontier
Sat, Mar 7 - Thu, Mar 19
Frontier Logo
1:54 pm - 12:08 am
STL
-
SAN
12h 14m
1 stop
Frontier Logo
2:08 pm - 11:19 am
SAN
-
STL
19h 11m
1 stop
$302Frontier
Mon, Feb 16 - Tue, Mar 10

Frontier flights from St. Louis to San Diego

Our best Frontier deals on St. Louis to San Diego flight tickets
Frontier
Mar 17
STL8:06 pmLambert-St Louis
19h 07m
1 stop
SAN1:13 pmSan Diego
Mar 22
SAN8:39 pmSan Diego
11h 10m
2 stops
STL9:49 amLambert-St Louis
$289
Frontier
Apr 17
STL3:02 pmLambert-St Louis
10h 59m
2 stops
SAN12:01 amSan Diego
Apr 20
SAN6:25 amSan Diego
10h 47m
1 stop
STL7:12 pmLambert-St Louis
$291
Frontier
Mar 13
STL8:12 pmLambert-St Louis
26h 21m
1 stop
SAN8:33 pmSan Diego
Mar 15
SAN9:18 pmSan Diego
10h 31m
1 stop
STL9:49 amLambert-St Louis
$292

Alaska Airlines flights from St. Louis to San Diego

Our best Alaska Airlines deals on St. Louis to San Diego flight tickets
Alaska Airlines
Mar 4
STL7:00 amLambert-St Louis
15h 39m
2 stops
SAN8:39 pmSan Diego
Mar 7
SAN8:26 pmSan Diego
14h 57m
1 stop
STL1:23 pmLambert-St Louis
$315
Alaska Airlines
Feb 28
STL2:47 pmLambert-St Louis
20h 02m
2 stops
SAN8:49 amSan Diego
Mar 2
SAN8:26 pmSan Diego
15h 25m
1 stop
STL1:51 pmLambert-St Louis
$335
Alaska Airlines
May 16
STL6:20 pmLambert-St Louis
7h 47m
1 stop
SAN12:07 amSan Diego
May 29
SAN7:00 amSan Diego
8h 06m
1 stop
STL5:06 pmLambert-St Louis
$357

momondo Fare Finder

 
Customize your flight search to find flights from St. Louis to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from St. Louis to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

Fri 2/27

8:00 am-2:29 pm

1 stop8h 29m

San Diego

Fri 3/6

10:35 pm-10:13 am

1 stop9h 38m

$287

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

Fri 2/27

1:59 pm-12:08 am

1 stop12h 09m

San Diego

Fri 3/6

9:58 pm-11:19 am

1 stop11h 21m

$289

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

Sun 4/26

11:21 am-12:11 am

2 stops38h 50m

San Diego

Sun 5/3

12:36 pm-7:12 pm

1 stop28h 36m

$290

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

Fri 4/17

3:02 pm-12:01 am

2 stops10h 59m

San Diego

Mon 4/27

6:25 am-7:12 pm

1 stop10h 47m

$291

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

Tue 3/17

1:00 pm-1:13 pm

1 stop26h 13m

San Diego

Sun 3/22

9:18 pm-9:49 am

1 stop10h 31m

$292

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

Mon 2/16

1:54 pm-12:08 am

1 stop12h 14m

San Diego

Tue 3/10

3:16 pm-9:49 am

2 stops16h 33m

$293

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

Sat 3/7

8:12 pm-11:08 pm

1 stop28h 56m

San Diego

Fri 3/20

9:58 pm-9:49 am

2 stops9h 51m

$297

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

Fri 4/17

8:12 pm-12:01 am

1 stop5h 49m

San Diego

Sun 4/19

6:25 am-7:12 pm

1 stop10h 47m

$300

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

Sat 3/7

8:12 pm-7:12 pm

2 stops25h 00m

San Diego

Thu 3/19

8:39 pm-11:19 am

1 stop12h 40m

$301

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

Mon 2/16

1:54 pm-12:08 am

1 stop12h 14m

San Diego

Tue 3/10

2:08 pm-11:19 am

1 stop19h 11m

$302

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from St. Louis to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of October, then departing from St. Louis during the month September is also very affordable. Most momondo users find prices during this month for around $331.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from St. Louis to San Diego is on a Wednesday. Travelers who choose to depart for San Diego on a Wednesday will often find tickets for as low as $414. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $567. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is in the afternoon when flights can be purchased for as low as $462. Flights at noon are often more expensive with an average ticket price of $585.

What is the cheapest Lambert-St Louis to San Diego flight route?

Fly from Lambert-St Louis to San Diego for the best Lambert-St Louis - San Diego flight prices

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from St. Louis when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $386 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from St. Louis for as low as $328 on momondo.

What cabin class options are available on Lambert-St Louis to San Diego flights?

There is only 1 cabin class available to choose from on Lambert-St Louis to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have St. Louis to San Diego flight prices changed over time?

As of February 2026, prices for St. Louis to San Diego flights are approximately 21% more expensive when compared to flights at the same time last year.

When to book flights from St. Louis to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from St. Louis to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap St. Louis to San Diego (STL to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to San Diego

Best Price Found

$179

Fastest flight time

3h 40m

Direct flights

Every day

Airports in San Diego

1 airport
The best one-way flight to San Diego from St. Louis in the past 72 hours is $179. The best round-trip flight deal from St. Louis to San Diego found on momondo in the last 72 hours is $377.
The fastest flight from St. Louis to San Diego takes 3h 40m
Direct flights go from St. Louis to San Diego every day.
There is 1 airport in San Diego. From St. Louis there are direct flights to San Diego (SAN).
Search flight deals

  • How far is Lambert-St Louis to San Diego by plane?

    There are 1560.0 mi between Lambert-St Louis and San Diego. By plane, this route typically takes 3h 40m.

  • When did momondo last update prices for flights from Lambert-St Louis Airport to San Diego Airport?

    Prices for flights from Lambert-St Louis Airport to San Diego Airport are updated daily.

  • How many operators does momondo search for flights from Lambert-St Louis Airport to San Diego Airport?

  • How old do you have to be to fly from Lambert-St Louis Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The travel and health documents you'll need for your trip to San Diego Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Diego Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from St. Louis to San Diego?

  • What is the most popular airline from St. Louis to San Diego?

Best airlines flying from St. Louis to San Diego

Compare and see reviews for airlines that fly from St. Louis to San Diego with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $88Free CancellationRating
5.7
3,051 reviews
Search Frontier flights
DeltaPriceFrom $138Free CancellationRating
7.9
8,138 reviews
Search Delta flights
United AirlinesPriceFrom $182Free CancellationRating
7.4
9,236 reviews
Search United Airlines flights
American AirlinesPriceFrom $235Free CancellationRating
7.2
11,216 reviews
Search American Airlines flights
SouthwestPriceFrom $308Free CancellationRating
8.0
4,272 reviews
Search Southwest flights

  • Southwest Flights From St. Louis to San Diego

    The lowest priced Southwest flight from St. Louis to San Diego from the last 72 hours was $308. Generally, Southwest has 4 flights on this route every week with an average price of $461. Southwest is rated 8.0/10 by our users.

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
Poway
National City
Imperial Beach
San Ysidro
Borrego Springs
La Mesa
Alpine
Lemon Grove
Santee

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to San Diego?

Finding the right flight to San Diego from St. Louis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Diego quick and easy, saving you time and money.

Can I find flights from St. Louis to San Diego with flexible booking policies on momondo?

Flights from St. Louis to San Diego with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from St. Louis to San Diego?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from St. Louis to San Diego.

I’m not ready to book a flight from St. Louis to San Diego right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Diego from St. Louis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your San Diego trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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