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Cheap flights from St. Louis to San Diego from $52

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to San Diego departing on 2/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from St. Louis to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
3:46 pm - 11:31 pm
STL
-
SAN
9h 45m1 stop
Frontier Logo
8:16 pm - 2:46 pm
SAN
-
STL
16h 30m1 stop
$109Frontier
Sat, Jan 31 - Fri, Feb 6
Frontier Logo
1:40 pm - 12:08 am
STL
-
SAN
12h 28m1 stop
Frontier Logo
8:16 pm - 2:46 pm
SAN
-
STL
16h 30m1 stop
$110Frontier
Mon, Feb 2 - Fri, Feb 6
Frontier Logo
1:40 pm - 12:08 am
STL
-
SAN
12h 28m1 stop
Frontier Logo
6:30 am - 6:44 pm
SAN
-
STL
10h 14m1 stop
$114Frontier
Mon, Jan 26 - Fri, Jan 30
Frontier Logo
4:51 pm - 9:41 pm
STL
-
SAN
6h 50m1 stop
Frontier Logo
9:09 am - 1:09 pm
SAN
-
STL
26h 00m1 stop
$115Frontier
Wed, Feb 25 - Sun, Mar 1
Frontier Logo
3:46 pm - 11:31 pm
STL
-
SAN
9h 45m1 stop
Frontier Logo
7:00 am - 2:46 pm
SAN
-
STL
5h 46m1 stop
$120Frontier
Wed, Jan 21 - Wed, Jan 28
Frontier Logo
3:46 pm - 11:31 pm
STL
-
SAN
9h 45m1 stop
Frontier Logo
8:16 pm - 12:50 pm
SAN
-
STL
14h 34m1 stop
$131Frontier
Sat, Jan 24 - Sun, Jan 25
Frontier Logo
3:46 pm - 11:31 pm
STL
-
SAN
9h 45m1 stop
Frontier Logo
6:25 am - 1:09 pm
SAN
-
STL
28h 44m1 stop
$135Frontier
Sat, Feb 7 - Thu, Feb 12
Frontier Logo
1:54 pm - 12:08 am
STL
-
SAN
12h 14m1 stop
Frontier Logo
9:58 pm - 7:11 pm
SAN
-
STL
19h 13m1 stop
$137Frontier
Mon, Mar 2 - Mon, Mar 9
Frontier Logo
3:46 pm - 3:11 pm
STL
-
SAN
25h 25m2 stops
Frontier Logo
8:16 pm - 2:46 pm
SAN
-
STL
16h 30m1 stop
$139Frontier
Sat, Jan 31 - Fri, Feb 6
Frontier Logo
1:40 pm - 12:08 am
STL
-
SAN
12h 28m1 stop
Frontier Logo
7:00 am - 9:06 pm
SAN
-
STL
36h 06m2 stops
$145Frontier
Mon, Feb 2 - Wed, Feb 4

Frontier flights from St. Louis to San Diego

Our best Frontier deals on St. Louis to San Diego flight tickets
Frontier
Jan 31
STL3:46 pmLambert-St Louis
9h 45m
1 stop
SAN11:31 pmSan Diego
Feb 6
SAN8:16 pmSan Diego
16h 30m
1 stop
STL2:46 pmLambert-St Louis
$109
Frontier
Feb 2
STL1:40 pmLambert-St Louis
12h 28m
1 stop
SAN12:08 amSan Diego
Feb 6
SAN8:16 pmSan Diego
16h 30m
1 stop
STL2:46 pmLambert-St Louis
$110
Frontier
Jan 26
STL1:40 pmLambert-St Louis
12h 28m
1 stop
SAN12:08 amSan Diego
Jan 30
SAN6:30 amSan Diego
10h 14m
1 stop
STL6:44 pmLambert-St Louis
$114

United Airlines flights from St. Louis to San Diego

Our best United Airlines deals on St. Louis to San Diego flight tickets
United Airlines
Jan 17
STL8:45 amLambert-St Louis
8h 19m
1 stop
SAN3:04 pmSan Diego
Jan 20
SAN1:00 pmSan Diego
5h 58m
1 stop
STL8:58 pmLambert-St Louis
$451
United Airlines
Jan 14
STL6:00 pmLambert-St Louis
6h 37m
1 stop
SAN10:37 pmSan Diego
Jan 17
SAN6:15 amSan Diego
12h 43m
2 stops
STL8:58 pmLambert-St Louis
$456
United Airlines
Jan 17
STL4:15 pmLambert-St Louis
9h 27m
2 stops
SAN11:42 pmSan Diego
Jan 20
SAN11:08 amSan Diego
7h 50m
2 stops
STL8:58 pmLambert-St Louis
$462

momondo Fare Finder

 
Customize your flight search to find flights from St. Louis to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 8, 2026.
Use the filters below to find and compare flights from St. Louis to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

Sat 1/31

3:46 pm-11:31 pm

1 stop9h 45m

San Diego

Fri 2/6

8:16 pm-2:46 pm

1 stop16h 30m

$109

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

Mon 2/2

1:40 pm-12:08 am

1 stop12h 28m

San Diego

Fri 2/6

8:16 pm-2:46 pm

1 stop16h 30m

$110

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

Mon 1/26

1:40 pm-12:08 am

1 stop12h 28m

San Diego

Fri 1/30

6:30 am-6:44 pm

1 stop10h 14m

$114

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

Wed 2/25

4:51 pm-9:41 pm

1 stop6h 50m

San Diego

Sun 3/1

9:09 am-1:09 pm

1 stop26h 00m

$115

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

Wed 1/21

3:46 pm-11:31 pm

1 stop9h 45m

San Diego

Wed 1/28

7:00 am-2:46 pm

1 stop5h 46m

$120

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

Sat 1/24

3:46 pm-11:31 pm

1 stop9h 45m

San Diego

Sun 1/25

8:16 pm-12:50 pm

1 stop14h 34m

$131

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

Sat 2/7

3:46 pm-11:31 pm

1 stop9h 45m

San Diego

Thu 2/12

6:25 am-1:09 pm

1 stop28h 44m

$135

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

Mon 3/2

1:54 pm-12:08 am

1 stop12h 14m

San Diego

Mon 3/9

9:58 pm-7:11 pm

1 stop19h 13m

$137

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

Sat 1/31

3:46 pm-3:11 pm

2 stops25h 25m

San Diego

Fri 2/6

8:16 pm-2:46 pm

1 stop16h 30m

$139

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

Mon 2/2

1:40 pm-12:08 am

1 stop12h 28m

San Diego

Wed 2/4

7:00 am-9:06 pm

2 stops36h 06m

$145

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from St. Louis to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of October, then departing from St. Louis during the month September is also very affordable. Most momondo users find prices during this month for around $324.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from St. Louis to San Diego is on a Wednesday. Travelers who choose to depart for San Diego on a Wednesday will often find tickets for as low as $427. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $542. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is in the afternoon when flights can be purchased for as low as $461. Flights at noon are often more expensive with an average ticket price of $601.

What is the cheapest Lambert-St Louis to San Diego flight route?

Fly from Lambert-St Louis to San Diego for the best Lambert-St Louis - San Diego flight prices

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from St. Louis when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $381 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from St. Louis for as low as $330 on momondo.

What cabin class options are available on Lambert-St Louis to San Diego flights?

There is only 1 cabin class available to choose from on Lambert-St Louis to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have St. Louis to San Diego flight prices changed over time?

As of January 2026, prices for St. Louis to San Diego flights are approximately 13% more expensive when compared to flights at the same time last year.

When to book flights from St. Louis to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from St. Louis to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap St. Louis to San Diego (STL to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to San Diego

Best Price Found

$398

Fastest flight time

3h 40m

Direct flights

Every day

Airports in San Diego

1 airport
The best flight deal from St. Louis to San Diego found on momondo in the last 72 hours is $398
The fastest flight from St. Louis to San Diego takes 3h 40m
Direct flights go from St. Louis to San Diego every day.
There is 1 airport in San Diego. From St. Louis there are direct flights to San Diego (SAN).
Search flight deals

  • How far is Lambert-St Louis to San Diego by plane?

    There are 1560.0 mi between Lambert-St Louis and San Diego. By plane, this route typically takes 3h 40m.

  • When did momondo last update prices for flights from Lambert-St Louis Airport to San Diego Airport?

    Prices for flights from Lambert-St Louis Airport to San Diego Airport are updated daily.

  • How many operators does momondo search for flights from Lambert-St Louis Airport to San Diego Airport?

  • How old do you have to be to fly from Lambert-St Louis Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The travel and health documents you'll need for your trip to San Diego Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Diego Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from St. Louis to San Diego?

  • What is the most popular airline from St. Louis to San Diego?

Best airlines flying from St. Louis to San Diego

Compare and see reviews for airlines that fly from St. Louis to San Diego with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $109Free CancellationRating
5.7
3,062 reviews
Search Frontier flights
United AirlinesPriceFrom $182Free CancellationRating
7.4
9,139 reviews
Search United Airlines flights
American AirlinesPriceFrom $237Free CancellationRating
7.2
11,095 reviews
Search American Airlines flights
DeltaPriceFrom $256Free CancellationRating
7.9
8,025 reviews
Search Delta flights
SouthwestPriceFrom $305Free CancellationRating
8.0
4,250 reviews
Search Southwest flights

  • Southwest Flights From St. Louis to San Diego

    The lowest priced Southwest flight from St. Louis to San Diego from the last 72 hours was $305. Generally, Southwest has 5 flights on this route every week with an average price of $472. Southwest is rated 8.0/10 by our users.

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
Poway
National City
Imperial Beach
Borrego Springs
La Mesa
San Ysidro
Alpine
Lemon Grove
Santee

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to San Diego?

Finding the right flight to San Diego from St. Louis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Diego quick and easy, saving you time and money.

Can I find flights from St. Louis to San Diego with flexible booking policies on momondo?

Flights from St. Louis to San Diego with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from St. Louis to San Diego?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from St. Louis to San Diego.

I’m not ready to book a flight from St. Louis to San Diego right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Diego from St. Louis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your San Diego trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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