Cheap flights from Spain to San Francisco from $375

If you aren’t able to travel to San Francisco during the month of October, then flying in March is also cheap. Prices for this month can be found on momondo for an average of $256.

The cheapest day to depart from Spain to San Francisco is on a Monday when prices can be found for as low as $763. The most expensive day to fly to San Francisco is Thursday, with ticket prices averaging around $1,382.

Fly from Madrid Barajas to San Francisco for the best Spain - San Francisco flight prices

You are more likely to see cheaper flights to San Francisco from Spain when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $708 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Spain for as low as $605 on momondo.

There are 3 cabin classes available to choose from on Spain to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 14% on your flight if you consider stops on a Spain to San Francisco flight.

British Airways, Finnair, and Iberia are the most popular carriers operating from Spain to San Francisco

Lufthansa, United Airlines and Iberia are the top three most popular airlines that fly to San Francisco from Spain according to our data. Lufthansa is the first choice among our users, with 28% of people opting to fly with this airline when traveling to San Francisco. Keep in mind that there are 11 different airlines that fly to San Francisco on a routine basis, so you have a few additional options to choose from.

Historically, on average around 17% of flights between Spain and San Francisco have experienced a delay on any given week. The average delay length over the past 12 months has been 171 minutes.

Generally, flights departing in the early afternoon tend to experience fewer delays. Flights in the morning have, in the past, seen delays more frequently in comparison.

Friday is statistically the day of the week which experiences the fewest number of delays on this flight route. Wednesday has historically seen more delays on average compared to the rest of the week.

According to our data, LEVEL have had the least number of delays on this route over the last 12 months; with about 14% of their flights experiencing any sort of delay.

As of June 2026, there are 5 flights per day flying from Spain to San Francisco. The most common time of day flights depart is 4:00PM, with 100% of flights taking off in the afternoon.

As of June 2026, there are 39 flights per week flying from Spain to San Francisco. The most common day of the week flights depart is Tue, with 23% of flights taking off on this day.