Cheap flights from Spain to San Francisco from $376

If you aren’t able to travel to San Francisco during the month of October, then flying in March is also cheap. Prices for this month can be found on momondo for an average of $256.

The cheapest day to depart from Spain to San Francisco is on a Thursday when prices can be found for as low as $690. The most expensive day to fly to San Francisco is Friday, with ticket prices averaging around $919.

Our data shows that the cheapest Spain to San Francisco flights are usually those with departure times at noon. Our users have found flights to San Francisco at noon for as low as $690. Flights in the afternoon are often more expensive with an average ticket price of $837.

Fly from Madrid Barajas to San Francisco for the best Spain - San Francisco flight prices

You are more likely to see cheaper flights to San Francisco from Spain when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $676 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Spain for as low as $592 on momondo.

British Airways, TAP AIR PORTUGAL, and Finnair are the most popular carriers operating from Spain to San Francisco

Iberia, Lufthansa and United Airlines are the top three most popular airlines that fly to San Francisco from Spain according to our data. Iberia is the first choice among our users, with 30% of people opting to fly with this airline when traveling to San Francisco. Keep in mind that there are 12 different airlines that fly to San Francisco on a routine basis, so you have a few additional options to choose from.

Historically, on average around 16% of flights between Spain and San Francisco have experienced a delay on any given week. The average delay length over the past 12 months has been 174 minutes.

Generally, flights departing in the early afternoon tend to experience fewer delays. Flights in the morning have, in the past, seen delays more frequently in comparison.

Friday is statistically the day of the week which experiences the fewest number of delays on this flight route. Wednesday has historically seen more delays on average compared to the rest of the week.

According to our data, LEVEL have had the least number of delays on this route over the last 12 months; with about 13% of their flights experiencing any sort of delay.

As of May 2026, there are 6 flights per day flying from Spain to San Francisco. The most common time of day flights depart is 12:00PM, with 100% of flights taking off in the afternoon.

As of May 2026, there are 42 flights per week flying from Spain to San Francisco. The most common day of the week flights depart is Mon, with 21% of flights taking off on this day.