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Cheap flights from Southampton to San Francisco from $581

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Southampton to San Francisco departing on 5/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Southampton to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
Aer Lingus Logo
9:20 am - 3:50 pm
SOU
-
SFO
14h 30m
1 stop
Aer Lingus Logo
5:35 pm - 7:30 pm
SFO
-
SOU
17h 55m
1 stop
$826Aer Lingus
Thu, Apr 30 - Thu, May 7
Aer Lingus Logo
8:00 pm - 3:55 pm
SOU
-
SFO
27h 55m
1 stop
Aer Lingus Logo
5:35 pm - 7:30 pm
SFO
-
SOU
17h 55m
1 stop
$844Aer Lingus
Mon, May 4 - Mon, May 11
Aer Lingus Logo
8:00 pm - 3:55 pm
SOU
-
SFO
27h 55m
1 stop
Aer Lingus Logo
5:35 pm - 8:35 am
SFO
-
SOU
31h 00m
1 stop
$854Aer Lingus
Fri, May 1 - Fri, May 8
KLM Logo
9:05 am - 8:51 pm
SOU
-
SFO
19h 46m
2 stops
KLM Logo
1:45 pm - 8:35 am
SFO
-
SOU
34h 50m
1 stop
$864KLM
Mon, May 4 - Mon, May 11
Multiple Airlines Logo
9:20 am - 3:50 pm
SOU
-
SFO
14h 30m
1 stop
Multiple Airlines Logo
5:35 pm - 5:40 pm
SFO
-
SOU
16h 05m
2 stops
$876Multiple Airlines
Thu, Apr 30 - Thu, May 7
Delta Logo
9:05 am - 11:18 pm
SOU
-
SFO
22h 13m
2 stops
Delta Logo
10:30 pm - 8:35 am
SFO
-
SOU
26h 05m
2 stops
$889Delta
Mon, May 4 - Mon, May 11
Delta Logo
9:05 am - 12:27 am
SOU
-
SFO
23h 22m
2 stops
Delta Logo
5:50 am - 8:35 am
SFO
-
SOU
18h 45m
2 stops
$895Delta
Thu, Apr 30 - Thu, May 7
KLM Logo
5:20 pm - 11:45 am
SOU
-
SFO
26h 25m
1 stop
KLM Logo
1:45 pm - 8:45 am
SFO
-
SOU
35h 00m
2 stops
$934KLM
Fri, May 1 - Fri, May 8
KLM Logo
5:20 pm - 6:22 pm
SOU
-
SFO
33h 02m
2 stops
KLM Logo
11:55 pm - 8:45 am
SFO
-
SOU
24h 50m
2 stops
$940KLM
Fri, May 1 - Fri, May 8
British Airways Logo
9:20 am - 3:55 pm
SOU
-
SFO
14h 35m
1 stop
British Airways Logo
5:40 pm - 7:30 pm
SFO
-
SOU
17h 50m
1 stop
$950British Airways
Wed, Sep 9 - Tue, Sep 22

Aer Lingus flights from Southampton to San Francisco

Our best Aer Lingus deals on Southampton to San Francisco flight tickets
Aer Lingus
May 5
SOU9:20 amSouthampton Eastleigh
14h 35m
1 stop
SFO3:55 pmSan Francisco
May 12
SFO5:40 pmSan Francisco
17h 50m
1 stop
SOU7:30 pmSouthampton Eastleigh
$800
Aer Lingus
Apr 30
SOU9:20 amSouthampton Eastleigh
14h 30m
1 stop
SFO3:50 pmSan Francisco
May 7
SFO5:35 pmSan Francisco
17h 55m
1 stop
SOU7:30 pmSouthampton Eastleigh
$826
Aer Lingus
May 4
SOU8:00 pmSouthampton Eastleigh
27h 55m
1 stop
SFO3:55 pmSan Francisco
May 11
SFO5:35 pmSan Francisco
17h 55m
1 stop
SOU7:30 pmSouthampton Eastleigh
$844

Delta flights from Southampton to San Francisco

Our best Delta deals on Southampton to San Francisco flight tickets
Delta
May 5
SOU5:20 pmSouthampton Eastleigh
26h 25m
1 stop
SFO11:45 amSan Francisco
May 12
SFO11:55 amSan Francisco
20h 55m
2 stops
SOU4:50 pmSouthampton Eastleigh
$887
Delta
May 4
SOU9:05 amSouthampton Eastleigh
22h 13m
2 stops
SFO11:18 pmSan Francisco
May 11
SFO10:30 pmSan Francisco
26h 05m
2 stops
SOU8:35 amSouthampton Eastleigh
$889
Delta
May 5
SOU9:05 amSouthampton Eastleigh
18h 51m
2 stops
SFO7:56 pmSan Francisco
May 12
SFO11:55 amSan Francisco
20h 55m
2 stops
SOU4:50 pmSouthampton Eastleigh
$892

momondo Fare Finder

 
Customize your flight search to find flights from Southampton to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 21, 2026.
Use the filters below to find and compare flights from Southampton to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Thu 4/30

9:20 am-3:50 pm

1 stop14h 30m

San Francisco

Thu 5/7

5:35 pm-7:30 pm

1 stop17h 55m

$826

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Mon 5/4

8:00 pm-3:55 pm

1 stop27h 55m

San Francisco

Mon 5/11

5:35 pm-7:30 pm

1 stop17h 55m

$844

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Fri 5/1

8:00 pm-3:55 pm

1 stop27h 55m

San Francisco

Fri 5/8

5:35 pm-8:35 am

1 stop31h 00m

$854

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Mon 5/4

9:05 am-8:51 pm

2 stops19h 46m

San Francisco

Mon 5/11

1:45 pm-8:35 am

1 stop34h 50m

$864
Quickest round-trip

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Thu 4/30

9:20 am-3:50 pm

1 stop14h 30m

San Francisco

Thu 5/7

5:35 pm-5:40 pm

2 stops16h 05m

$876

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Mon 5/4

9:05 am-11:18 pm

2 stops22h 13m

San Francisco

Mon 5/11

10:30 pm-8:35 am

2 stops26h 05m

$889

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Thu 4/30

9:05 am-12:27 am

2 stops23h 22m

San Francisco

Thu 5/7

5:50 am-8:35 am

2 stops18h 45m

$895

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Fri 5/1

5:20 pm-11:45 am

1 stop26h 25m

San Francisco

Fri 5/8

1:45 pm-8:45 am

2 stops35h 00m

$934

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Fri 5/1

5:20 pm-6:22 pm

2 stops33h 02m

San Francisco

Fri 5/8

11:55 pm-8:45 am

2 stops24h 50m

$940

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Wed 9/9

9:20 am-3:55 pm

1 stop14h 35m

San Francisco

Tue 9/22

5:40 pm-7:30 pm

1 stop17h 50m

$950

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Southampton to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Southampton to San Francisco is on a Thursday when prices can be found for as low as $680. The most expensive day to fly to San Francisco is Monday, with ticket prices averaging around $761.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Southampton to San Francisco flights are usually those with departure times at noon. Our users have found flights to San Francisco at noon for as low as $706. Flights in the morning are often more expensive with an average ticket price of $752.

When to book flights from Southampton to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Southampton to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Southampton to San Francisco (SOU to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Southampton to San Francisco

Fastest flight time

14h 35m

Direct flights

None
The fastest flight from Southampton to San Francisco takes 14h 35m
There are no direct flights from Southampton to San Francisco. There are no popular flight routes from Southampton to San Francisco.
Search flight deals

  • How far is Southampton Eastleigh to San Francisco by plane?

    A flight from Southampton Eastleigh to San Francisco will travel around 5341.1 mi. A reasonable flight in good conditions will take 14h 35m.

  • When did momondo last update prices for flights from Southampton Eastleigh Airport to San Francisco Airport?

    Prices for flights from Southampton Eastleigh Airport to San Francisco Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Southampton Eastleigh Airport to San Francisco Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Southampton Eastleigh Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The travel and health documents required for your trip to San Francisco Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at San Francisco Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Walnut Creek
Roseville
Hayward
Berkeley
Santa Clara
Big Sur
Fremont
Calistoga
Vallejo
Salinas
Half Moon Bay
Daly City
Milpitas
Pacific Grove
South San Francisco

Why use momondo?

Why should I use momondo to find a flight deal from Southampton to San Francisco?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Southampton to San Francisco. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Southampton to San Francisco with flexible booking policies on momondo?

All flight searches from Southampton to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Southampton to San Francisco?

Once all potential Southampton to San Francisco flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Southampton to San Francisco right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Southampton to San Francisco flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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