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Cheap flights from Southampton to San Francisco from $473

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Southampton to San Francisco departing on 1/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

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Virgin Atlantic Logo
6:05 pm - 11:50 amSOU-SFO
25h 45m1 stop
Virgin Atlantic Logo
1:55 pm - 5:00 pmSFO-SOU
19h 05m1 stop
$636Virgin Atlantic
Find Deal
Thu, Dec 4 - Mon, Dec 8
KLM Logo
6:05 pm - 11:50 amSOU-SFO
25h 45m1 stop
KLM Logo
2:00 pm - 5:00 pmSFO-SOU
19h 00m2 stops
$654KLM
Find Deal
Thu, Dec 4 - Mon, Dec 8
KLM Logo
8:50 am - 6:04 pmSOU-SFO
17h 14m2 stops
KLM Logo
7:00 am - 8:10 amSFO-SOU
17h 10m2 stops
$660KLM
Find Deal
Thu, Dec 4 - Mon, Dec 8
Delta Logo
5:30 pm - 12:50 pmSOU-SFO
26h 20m1 stop
Delta Logo
1:45 pm - 5:00 pmSFO-SOU
19h 15m1 stop
$661Delta
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Fri, Mar 27 - Tue, Mar 31
Delta Logo
5:30 pm - 5:52 pmSOU-SFO
31h 22m2 stops
Delta Logo
2:00 pm - 5:00 pmSFO-SOU
19h 00m2 stops
$666Delta
Find Deal
Fri, Mar 27 - Tue, Mar 31
Delta Logo
5:30 pm - 5:52 pmSOU-SFO
31h 22m2 stops
Delta Logo
12:00 pm - 5:00 pmSFO-SOU
21h 00m2 stops
$667Delta
Find Deal
Fri, Mar 27 - Tue, Mar 31
British Airways Logo
9:30 am - 3:35 pmSOU-SFO
14h 05m1 stop
British Airways Logo
5:20 pm - 7:40 pmSFO-SOU
18h 20m1 stop
$1,235British Airways
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Sat, Nov 29 - Sat, Feb 14
British Airways Logo
7:55 pm - 3:00 pmSOU-SFO
27h 05m2 stops
British Airways Logo
6:30 pm - 8:20 pmSFO-SOU
18h 50m2 stops
$1,238British Airways
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Wed, Nov 19 - Tue, Mar 10
Multiple Airlines Logo
9:30 am - 1:25 pmSOU-SFO
35h 55m3 stops
Multiple Airlines Logo
1:55 pm - 7:40 pmSFO-SOU
21h 45m2 stops
$1,240Multiple Airlines
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Thu, Dec 4 - Mon, Dec 8
Multiple Airlines Logo
12:20 pm - 11:50 amSOU-SFO
31h 30m3 stops
Multiple Airlines Logo
8:25 am - 2:05 pmSFO-SOU
21h 40m3 stops
$1,508Multiple Airlines
Find Deal
Thu, Dec 4 - Mon, Dec 8

Virgin Atlantic flights from Southampton to San Francisco

Our best Virgin Atlantic deals on Southampton to San Francisco flight tickets
Virgin Atlantic
Dec 4
SOU6:05 pmSouthampton Eastleigh
25h 45m
1 stop
SFO11:50 amSan Francisco
Dec 8
SFO1:55 pmSan Francisco
19h 05m
1 stop
SOU5:00 pmSouthampton Eastleigh
$636
Find similar
Virgin Atlantic
Dec 16
SOU5:30 pmSouthampton Eastleigh
26h 20m
1 stop
SFO11:50 amSan Francisco
Dec 23
SFO5:50 amSan Francisco
27h 10m
2 stops
SOU5:00 pmSouthampton Eastleigh
$881
Find similar
Virgin Atlantic
Dec 22
SOU6:05 pmSouthampton Eastleigh
25h 45m
1 stop
SFO11:50 amSan Francisco
Jan 2
SFO1:55 pmSan Francisco
19h 05m
1 stop
SOU5:00 pmSouthampton Eastleigh
$1,041
Find similar

KLM flights from Southampton to San Francisco

Our best KLM deals on Southampton to San Francisco flight tickets
KLM
Dec 4
SOU6:05 pmSouthampton Eastleigh
25h 45m
1 stop
SFO11:50 amSan Francisco
Dec 8
SFO2:00 pmSan Francisco
19h 00m
2 stops
SOU5:00 pmSouthampton Eastleigh
$654
Find similar
KLM
Dec 4
SOU8:50 amSouthampton Eastleigh
17h 14m
2 stops
SFO6:04 pmSan Francisco
Dec 8
SFO7:00 amSan Francisco
17h 10m
2 stops
SOU8:10 amSouthampton Eastleigh
$660
Find similar
KLM
Dec 18
SOU6:05 pmSouthampton Eastleigh
27h 20m
2 stops
SFO1:25 pmSan Francisco
Dec 25
SFO1:55 pmSan Francisco
34h 55m
1 stop
SOU8:50 amSouthampton Eastleigh
$848
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Southampton to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Southampton to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Thu 12/4

6:05 pm-11:50 am

1 stop25h 45m

San Francisco

Mon 12/8

1:55 pm-5:00 pm

1 stop19h 05m

$636

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Thu 12/4

6:05 pm-11:50 am

1 stop25h 45m

San Francisco

Mon 12/8

2:00 pm-5:00 pm

2 stops19h 00m

$654

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Thu 12/4

8:50 am-6:04 pm

2 stops17h 14m

San Francisco

Mon 12/8

7:00 am-8:10 am

2 stops17h 10m

$660

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Fri 3/27

5:30 pm-12:50 pm

1 stop26h 20m

San Francisco

Tue 3/31

1:45 pm-5:00 pm

1 stop19h 15m

$661

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Fri 3/27

5:30 pm-5:52 pm

2 stops31h 22m

San Francisco

Tue 3/31

2:00 pm-5:00 pm

2 stops19h 00m

$666

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Fri 3/27

5:30 pm-5:52 pm

2 stops31h 22m

San Francisco

Tue 3/31

12:00 pm-5:00 pm

2 stops21h 00m

$667

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Sat 11/29

9:30 am-3:35 pm

1 stop14h 05m

San Francisco

Sat 2/14

5:20 pm-7:40 pm

1 stop18h 20m

$1,235

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Wed 11/19

7:55 pm-3:00 pm

2 stops27h 05m

San Francisco

Tue 3/10

6:30 pm-8:20 pm

2 stops18h 50m

$1,238

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Thu 12/4

9:30 am-1:25 pm

3 stops35h 55m

San Francisco

Mon 12/8

1:55 pm-7:40 pm

2 stops21h 45m

$1,240

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Thu 12/4

12:20 pm-11:50 am

3 stops31h 30m

San Francisco

Mon 12/8

8:25 am-2:05 pm

3 stops21h 40m

$1,508

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Southampton to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Southampton to San Francisco is on a Thursday when prices can be found for as low as $680. The most expensive day to fly to San Francisco is Sunday, with ticket prices averaging around $750.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Southampton to San Francisco flights are usually those with departure times in the evening. Our users have found flights to San Francisco in the evening for as low as $682. Flights in the afternoon are often more expensive with an average ticket price of $727.

When to book flights from Southampton to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Southampton to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Southampton to San Francisco (SOU to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Southampton to San Francisco

Direct flights

None
There are no direct flights from Southampton to San Francisco. There are no popular flight routes from Southampton to San Francisco.
Search flight deals

  • How far is Southampton Eastleigh to San Francisco by plane?

    A flight from Southampton Eastleigh to San Francisco will travel around 5341.1 mi. A reasonable flight in good conditions will take 14h 05m.

  • When did momondo last update prices for flights from Southampton Eastleigh Airport to San Francisco Airport?

    Prices for flights from Southampton Eastleigh Airport to San Francisco Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Southampton Eastleigh Airport to San Francisco Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Southampton Eastleigh Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The travel and health documents required for your trip to San Francisco Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at San Francisco Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Roseville
Calistoga
Hayward
Big Sur
Santa Clara
Daly City
Fremont
Berkeley
Vallejo
Walnut Creek
Half Moon Bay
Salinas
Turlock
Livermore
Pacific Grove

Why use momondo?

Why should I use momondo to find a flight deal from Southampton to San Francisco?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Southampton to San Francisco. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Southampton to San Francisco with flexible booking policies on momondo?

All flight searches from Southampton to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Southampton to San Francisco?

Once all potential Southampton to San Francisco flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Southampton to San Francisco right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Southampton to San Francisco flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your San Francisco trip

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