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Cheap flights from Southampton to San Francisco from $599

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Southampton to San Francisco departing on 11/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

KLM Logo
6:05 pm - 12:50 pmSOU-SFO
25h 45m1 stop
KLM Logo
1:55 pm - 5:00 pmSFO-SOU
19h 05m1 stop
$650KLM
Find Deal
Thu, Oct 30 - Thu, Nov 6
Delta Logo
6:05 pm - 12:50 pmSOU-SFO
25h 45m1 stop
Delta Logo
12:35 am - 8:05 amSFO-SOU
23h 30m2 stops
$651Delta
Find Deal
Thu, Oct 30 - Wed, Nov 5
Delta Logo
8:50 am - 10:35 pmSOU-SFO
20h 45m2 stops
Delta Logo
12:35 am - 8:05 amSFO-SOU
23h 30m2 stops
$657Delta
Find Deal
Thu, Oct 30 - Wed, Nov 5
Delta Logo
9:25 am - 10:30 pmSOU-SFO
20h 05m2 stops
Delta Logo
12:35 am - 8:50 amSFO-SOU
24h 15m2 stops
$660Delta
Find Deal
Sat, Nov 1 - Fri, Nov 7
KLM Logo
9:25 am - 10:30 pmSOU-SFO
20h 05m2 stops
KLM Logo
1:55 pm - 8:10 amSFO-SOU
34h 15m1 stop
$673KLM
Find Deal
Sat, Nov 1 - Sat, Nov 8
Aer Lingus Logo
9:30 am - 4:35 pmSOU-SFO
14h 05m1 stop
Aer Lingus Logo
5:20 pm - 7:40 pmSFO-SOU
18h 20m1 stop
$687Aer Lingus
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Sat, Nov 1 - Sat, Nov 8
British Airways Logo
9:30 am - 3:35 pmSOU-SFO
14h 05m1 stop
British Airways Logo
5:20 pm - 7:40 pmSFO-SOU
18h 20m1 stop
$798British Airways
Find Deal
Fri, Nov 7 - Tue, Nov 11
British Airways Logo
9:30 am - 3:35 pmSOU-SFO
14h 05m1 stop
British Airways Logo
5:30 pm - 7:25 pmSFO-SOU
17h 55m2 stops
$841British Airways
Find Deal
Fri, Nov 7 - Tue, Nov 11
Multiple Airlines Logo
2:45 pm - 4:00 pmSOU-SFO
32h 15m3 stops
Multiple Airlines Logo
3:28 pm - 7:40 pmSFO-SOU
20h 12m2 stops
$1,072Multiple Airlines
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Thu, Oct 30 - Thu, Nov 6
Multiple Airlines Logo
5:30 pm - 3:35 pmSOU-SFO
29h 05m3 stops
Multiple Airlines Logo
4:40 pm - 8:10 amSFO-SOU
31h 30m3 stops
$1,183Multiple Airlines
Find Deal
Sat, Nov 1 - Sat, Nov 8

British Airways flights from Southampton to San Francisco

Our best British Airways deals on Southampton to San Francisco flight tickets
British Airways
Nov 7
SOU9:30 amSouthampton Eastleigh
14h 05m
1 stop
SFO3:35 pmSan Francisco
Nov 11
SFO5:20 pmSan Francisco
18h 20m
1 stop
SOU7:40 pmSouthampton Eastleigh
$798
Find similar
British Airways
Nov 7
SOU9:30 amSouthampton Eastleigh
14h 05m
1 stop
SFO3:35 pmSan Francisco
Nov 11
SFO5:30 pmSan Francisco
17h 55m
2 stops
SOU7:25 pmSouthampton Eastleigh
$841
Find similar
British Airways
Sep 30
SOU7:55 pmSouthampton Eastleigh
29h 30m
2 stops
SFO5:25 pmSan Francisco
Oct 7
SFO5:40 pmSan Francisco
17h 50m
1 stop
SOU7:30 pmSouthampton Eastleigh
$1,020
Find similar

KLM flights from Southampton to San Francisco

Our best KLM deals on Southampton to San Francisco flight tickets
KLM
Oct 30
SOU6:05 pmSouthampton Eastleigh
25h 45m
1 stop
SFO12:50 pmSan Francisco
Nov 6
SFO1:55 pmSan Francisco
19h 05m
1 stop
SOU5:00 pmSouthampton Eastleigh
$650
Find similar
KLM
Nov 1
SOU9:25 amSouthampton Eastleigh
20h 05m
2 stops
SFO10:30 pmSan Francisco
Nov 8
SFO1:55 pmSan Francisco
34h 15m
1 stop
SOU8:10 amSouthampton Eastleigh
$673
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Southampton to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Southampton to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Thu 10/30

6:05 pm-12:50 pm

1 stop25h 45m

San Francisco

Thu 11/6

1:55 pm-5:00 pm

1 stop19h 05m

$650

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Thu 10/30

6:05 pm-12:50 pm

1 stop25h 45m

San Francisco

Wed 11/5

12:35 am-8:05 am

2 stops23h 30m

$651

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Thu 10/30

8:50 am-10:35 pm

2 stops20h 45m

San Francisco

Wed 11/5

12:35 am-8:05 am

2 stops23h 30m

$657

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Sat 11/1

9:25 am-10:30 pm

2 stops20h 05m

San Francisco

Fri 11/7

12:35 am-8:50 am

2 stops24h 15m

$660

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Sat 11/1

9:25 am-10:30 pm

2 stops20h 05m

San Francisco

Sat 11/8

1:55 pm-8:10 am

1 stop34h 15m

$673

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Sat 11/1

9:30 am-4:35 pm

1 stop14h 05m

San Francisco

Sat 11/8

5:20 pm-7:40 pm

1 stop18h 20m

$687

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Fri 11/7

9:30 am-3:35 pm

1 stop14h 05m

San Francisco

Tue 11/11

5:20 pm-7:40 pm

1 stop18h 20m

$798

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Fri 11/7

9:30 am-3:35 pm

1 stop14h 05m

San Francisco

Tue 11/11

5:30 pm-7:25 pm

2 stops17h 55m

$841

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Thu 10/30

2:45 pm-4:00 pm

3 stops32h 15m

San Francisco

Thu 11/6

3:28 pm-7:40 pm

2 stops20h 12m

$1,072

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Sat 11/1

5:30 pm-3:35 pm

3 stops29h 05m

San Francisco

Sat 11/8

4:40 pm-8:10 am

3 stops31h 30m

$1,183

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Southampton to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Southampton to San Francisco is on a Thursday when prices can be found for as low as $646. The most expensive day to fly to San Francisco is Sunday, with ticket prices averaging around $750.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Southampton to San Francisco flights are usually those with departure times in the evening. Our users have found flights to San Francisco in the evening for as low as $682. Flights in the morning are often more expensive with an average ticket price of $718.

When to book flights from Southampton to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Southampton to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Southampton to San Francisco (SOU to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Southampton to San Francisco

Direct flights

None
There are no direct flights from Southampton to San Francisco. There are no popular flight routes from Southampton to San Francisco.
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  • How far is Southampton Eastleigh to San Francisco by plane?

    A flight from Southampton Eastleigh to San Francisco will travel around 5341.1 mi. A reasonable flight in good conditions will take 14h 05m.

  • When did momondo last update prices for flights from Southampton Eastleigh Airport to San Francisco Airport?

    Prices for flights from Southampton Eastleigh Airport to San Francisco Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Southampton Eastleigh Airport to San Francisco Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Southampton Eastleigh Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The travel and health documents required for your trip to San Francisco Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at San Francisco Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Calistoga
Bodega Bay
Roseville
Hayward
Big Sur
Santa Clara
Daly City
Fremont
Berkeley
Half Moon Bay
Walnut Creek
Vallejo
Redwood City
Salinas
South San Francisco
Fairfield

Why use momondo?

Why should I use momondo to find a flight deal from Southampton to San Francisco?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Southampton to San Francisco. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Southampton to San Francisco with flexible booking policies on momondo?

All flight searches from Southampton to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Southampton to San Francisco?

Once all potential Southampton to San Francisco flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Southampton to San Francisco right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Southampton to San Francisco flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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