Cheap flights from Washington, D.C. Reagan-National Airport to San Diego from $149

If you are unable to visit San Diego during the month of January, then departing from Washington, D.C. Reagan-National Airport during the month September is also very affordable. Most momondo users find prices during this month for around $347.

The cheapest day to depart from Washington, D.C. Reagan-National Airport to San Diego is on a Thursday. Travelers who choose to depart for San Diego on a Thursday will often find tickets for as low as $387. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $470. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

The cheapest time of day to fly to San Diego is in the evening when flights can be purchased for as low as $387. Flights at noon are often more expensive with an average ticket price of $542.

Fly from Washington, D.C. Reagan-National to San Diego for the best Washington, D.C. Reagan-National - San Diego flight prices

You are more likely to see cheaper flights to San Diego from Washington, D.C. Reagan-National Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $380 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Washington, D.C. Reagan-National Airport for as low as $280 on momondo.

There are 4 cabin classes available to choose from on Washington, D.C. Reagan-National to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 6% on your flight if you consider stops on a Washington, D.C. Reagan-National Airport to San Diego flight.

As of April 2026, prices for Washington, D.C. Reagan-National Airport to San Diego flights are approximately 13% more expensive when compared to flights at the same time last year.

Southwest, United Airlines, and Delta are the most popular carriers operating from Washington, D.C. Reagan-National to San Diego

Alaska Airlines, American Airlines and Frontier are the top three most popular airlines that fly to San Diego from Washington, D.C. Reagan-National Airport according to our data. Alaska Airlines is the first choice among our users, with 42% of people opting to fly with this airline when traveling to San Diego. Keep in mind that there are 7 different airlines that fly to San Diego on a routine basis, so you have a few additional options to choose from.

Denver (DEN) was the most common stop: 83% of momondo users choosing 1-stop flights on this route connected there.

Flights via Chicago (ORD) offer the lowest average round-trip price of $296.

Flights connecting via Chicago (ORD) have the shortest average one-way travel time: 7h 20m.

Chicago (ORD) has the shortest average layover time for this route: 1h 05m.

The number of flights available between Washington, D.C. Reagan-National Airport and San Diego is 1 per day as of April 2026. The most frequent departure time is 8:00AM, with 78% of daily flights leaving at noon.

As of April 2026, there are 11 flights per week flying from Washington, D.C. Reagan-National Airport to San Diego. The most common day of the week flights depart is Mon, with 27% of flights taking off on this day.