Cheap flights from Portland to Los Angeles from $73

In general, January is the cheapest month to fly from Portland to Santa Ana, California. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $294. If you aren’t able to travel during the month of January, then book flights to Santa Ana, California from Portland during February instead. Flights to Santa Ana, California in February, while not as cheap as those in January, still average around $315.

The cheapest day to depart from Portland to Santa Ana, California is on a Thursday. Travelers who choose to depart for Santa Ana, California on a Thursday will often find tickets for as low as $330. The most expensive day to fly to Santa Ana, California is Sunday, with ticket prices averaging around $386.

In the evening is the cheapest time of day to fly from Portland to Santa Ana, California when you can find flight prices for as low as $317. Flying to Santa Ana, California in the evening is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Santa Ana, California is at noon when prices are around $354.

Fly from Portland to Santa Ana J. Wayne/Orange Cnty for the best Portland - Santa Ana J. Wayne/Orange Cnty flight prices

You are more likely to see cheaper flights to Santa Ana, California from Portland when booking weeks ahead of your departure date. In general, you can expect to find flights to Santa Ana, California for around $338 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santa Ana, California from Portland for as low as $288 on momondo.

There are 4 cabin classes available to choose from on Portland to Santa Ana, California flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 40% on your flight if you consider stops on a Portland to Santa Ana, California flight.

As of October 2026, prices for Portland to Santa Ana, California flights are approximately 16% more expensive when compared to flights at the same time last year.

Southwest and Alaska Airlines are the most popular carriers operating from Portland to Santa Ana J. Wayne/Orange Cnty

Alaska Airlines, Delta and Frontier are the top three most popular airlines that fly to Santa Ana, California from Portland according to our data. Alaska Airlines is the first choice among our users, with 56% of people opting to fly with this airline when traveling to Santa Ana, California. Keep in mind that there are 8 different airlines that fly to Santa Ana, California on a routine basis, so you have a few additional options to choose from.

San Jose (SJC) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

Flights via Seattle (SEA) offer the lowest average round-trip price of $266.

Flights connecting via Seattle (SEA) have the shortest average one-way travel time: 4h 40m.

Seattle (SEA) has the shortest average layover time for this route: 0h 46m.

3 flights are operational daily from Portland to Santa Ana, California as of October 2026. The most popular departure time for this route is 2:00PM, with 64% of flights per day taking off in the afternoon.

The number of flights available between Portland and Santa Ana, California is 25 per week as of October 2026. The most frequent departure day is Mon, with 24% of weekly flights leaving on this day.