Cheap flights from Portland to San Diego from $80

If you are unable to visit San Diego during the month of January, then departing from Portland during the month September is also very affordable. Most momondo users find prices during this month for around $257.

The cheapest day to depart from Portland to San Diego is on a Tuesday. Travelers who choose to depart for San Diego on a Tuesday will often find tickets for as low as $266. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $334. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

The cheapest time of day to fly to San Diego is in the evening when flights can be purchased for as low as $290. Flights in the morning are often more expensive with an average ticket price of $318.

Fly from Portland to San Diego for the best Portland - San Diego flight prices

You are more likely to see cheaper flights to San Diego from Portland when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $280 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Portland for as low as $240 on momondo.

There are 4 cabin classes available to choose from on Portland to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Southwest is the most popular carrier operating from Portland to San Diego

Alaska Airlines, Southwest and Hawaiian Airlines are the top three most popular airlines that fly to San Diego from Portland according to our data. Alaska Airlines is the first choice among our users, with 72% of people opting to fly with this airline when traveling to San Diego. Keep in mind that there are 8 different airlines that fly to San Diego on a routine basis, so you have a few additional options to choose from.

Historically, on average around 12% of flights between Portland and San Diego have experienced a delay on any given week. The average delay length over the past 12 months has been 107 minutes.

Generally, flights departing in the early afternoon tend to experience fewer delays. Flights in the evening have, in the past, seen delays more frequently in comparison.

Saturday is statistically the day of the week which experiences the fewest number of delays on this flight route. Thursday has historically seen more delays on average compared to the rest of the week.

According to our data, Alaska Airlines have had the least number of delays on this route over the last 12 months; with about 12% of their flights experiencing any sort of delay.

Las Vegas (LAS) was the most common stop: 83% of momondo users choosing 1-stop flights on this route connected there.

Flights via Phoenix (PHX) offer the lowest average round-trip price of $145.

Flights connecting via Las Vegas (LAS) have the shortest average one-way travel time: 4h 59m.

San Jose (SJC) has the shortest average layover time for this route: 1h 40m.

9 flights are operational daily from Portland to San Diego as of February 2026. The most popular departure time for this route is 2:00PM, with 58% of flights per day taking off in the afternoon.

The number of flights available between Portland and San Diego is 68 per week as of February 2026. The most frequent departure day is Fri, with 22% of weekly flights leaving on this day.