Cheap flights from Pennsylvania to San Francisco from $135

If you aren’t able to travel to San Francisco during the month of September, then flying in October is also cheap. Prices for this month can be found on momondo for an average of $394.

The cheapest day to depart from Pennsylvania to San Francisco is on a Wednesday when prices can be found for as low as $451. The most expensive day to fly to San Francisco is Monday, with ticket prices averaging around $702.

Our data shows that the cheapest Pennsylvania to San Francisco flights are usually those with departure times in the evening. Our users have found flights to San Francisco in the evening for as low as $387. Flights in the morning are often more expensive with an average ticket price of $515.

Fly from Pittsburgh to San Francisco for the best Pennsylvania - San Francisco flight prices

You are more likely to see cheaper flights to San Francisco from Pennsylvania when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $418 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Pennsylvania for as low as $355 on momondo.

There are 4 cabin classes available to choose from on Pennsylvania to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Delta, Alaska Airlines, and Southwest are the most popular carriers operating from Pennsylvania to San Francisco

American Airlines, United Airlines and Southwest are the top three most popular airlines that fly to San Francisco from Pennsylvania according to our data. American Airlines is the first choice among our users, with 49% of people opting to fly with this airline when traveling to San Francisco. Keep in mind that there are 6 different airlines that fly to San Francisco on a routine basis, so you have a few additional options to choose from.

As of July 2026, there are 197 flights per day flying from Pennsylvania to San Francisco. The most common time of day flights depart is 6:00AM, with 43% of flights taking off at noon.

The number of flights available between Pennsylvania and San Francisco is 1,379 per week as of July 2026. The most frequent departure day is Sun, with 16% of weekly flights leaving on this day.