Cheap flights from Pennsylvania to San Diego from $85

If you are unable to visit San Diego during the month of November, then departing from Pennsylvania during the month September is also very affordable. Most momondo users find prices during this month for around $103.

The cheapest day to depart from Pennsylvania to San Diego is on a Tuesday. Travelers who choose to depart for San Diego on a Tuesday will often find tickets for as low as $422. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $584. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

The cheapest time of day to fly to San Diego is in the evening when flights can be purchased for as low as $433. Flights in the morning are often more expensive with an average ticket price of $476.

Fly from Pittsburgh to San Diego for the best Pennsylvania - San Diego flight prices

You are more likely to see cheaper flights to San Diego from Pennsylvania when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $448 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Pennsylvania for as low as $401 on momondo.

United Airlines, Delta, and American Airlines are the most popular carriers operating from Pennsylvania to San Diego

American Airlines, United Airlines and Southwest are the top three most popular airlines that fly to San Diego from Pennsylvania according to our data. American Airlines is the first choice among our users, with 68% of people opting to fly with this airline when traveling to San Diego. Keep in mind that there are 8 different airlines that fly to San Diego on a routine basis, so you have a few additional options to choose from.

As of May 2026, there are 45 flights per day flying from Pennsylvania to San Diego. The most common time of day flights depart is 3:00PM, with 42% of flights taking off in the afternoon.

The number of flights available between Pennsylvania and San Diego is 318 per week as of May 2026. The most frequent departure day is Fri, with 18% of weekly flights leaving on this day.