Cheap flights from Philadelphia to Knoxville from $34

The month of August is, on average, the cheapest month to fly to Knoxville from Philadelphia, with most prices found around $138. If you aren’t able to travel during the month of August, then book flights to Knoxville from Philadelphia during July instead. Flights to Knoxville in July, while not as cheap as those in August, still average around $160.

The cheapest day to depart from Philadelphia to Knoxville is on a Thursday. Travelers who choose to depart for Knoxville on a Thursday will often find tickets for as low as $270. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from Philadelphia to Knoxville for around $471.

In the afternoon is the cheapest time of day to fly from Philadelphia to Knoxville when you can find flight prices for as low as $150. Flying to Knoxville in the afternoon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the evening when prices are around $497.

Fly from Philadelphia to Knoxville McGhee Tyson for the best Philadelphia - Knoxville McGhee Tyson flight prices

You are more likely to see cheaper flights to Knoxville from Philadelphia when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $407 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Philadelphia for as low as $305 on momondo.

There are 3 cabin classes available to choose from on Philadelphia to Knoxville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

No. A direct flight is the cheapest option for a flight between Philadelphia to Knoxville.

Southwest and Delta are the most popular carriers operating from Philadelphia to Knoxville McGhee Tyson

American Airlines, Allegiant Air and Delta are the top three most popular airlines that fly to Knoxville from Philadelphia according to our data. American Airlines is the first choice among our users, with 38% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 5 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.

As of August 2026, there are 6 flights per day flying from Philadelphia to Knoxville. The most common time of day flights depart is 5:00PM, with 72% of flights taking off in the afternoon.

48 flights are operational weekly from Philadelphia to Knoxville as of August 2026. The most popular departure day for this route is Sat, with 17% of flights per week taking off on this day.