Cheap flights from Ohio to San Diego from $107

If you are unable to visit San Diego during the month of January, then departing from Ohio during the month April is also very affordable. Most momondo users find prices during this month for around $371.

Fly from Cincinnati Cinci./N. Kentucky to San Diego for the best Ohio - San Diego flight prices

You are more likely to see cheaper flights to San Diego from Ohio when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $428 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Ohio for as low as $375 on momondo.

There are 2 cabin classes available to choose from on Ohio to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Frontier, Breeze Airways, and Delta are the most popular carriers operating from Ohio to San Diego

American Airlines, United Airlines and Southwest are the top three most popular airlines that fly to San Diego from Ohio according to our data. American Airlines is the first choice among our users, with 37% of people opting to fly with this airline when traveling to San Diego. Keep in mind that there are 8 different airlines that fly to San Diego on a routine basis, so you have a few additional options to choose from.

The number of flights available between Ohio and San Diego is 1 per day as of November 2026. The most frequent departure time is 10:00AM, with 75% of daily flights leaving at noon.

As of November 2026, 8 flights take off from Ohio and land in San Diego each week. The most common flight departure day for this route is Mon, with 38% of weekly flights taking off on this day.