Cheap flights from Michigan to San Diego from $115

If you are unable to visit San Diego during the month of October, then departing from Michigan during the month March is also very affordable. Most momondo users find prices during this month for around $69.

The cheapest day to depart from Michigan to San Diego is on a Friday. Travelers who choose to depart for San Diego on a Friday will often find tickets for as low as $499. If your travel schedule is flexible, try to avoid departing on a Wednesday because tickets tend to average around $572. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

The cheapest time of day to fly to San Diego is in the morning when flights can be purchased for as low as $500. Flights in the evening are often more expensive with an average ticket price of $578.

Fly from Detroit Metropolitan Wayne County to San Diego for the best Michigan - San Diego flight prices

You are more likely to see cheaper flights to San Diego from Michigan when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $444 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Michigan for as low as $354 on momondo.

United Airlines, Frontier, and Alaska Airlines are the most popular carriers operating from Michigan to San Diego

Delta, American Airlines and United Airlines are the top three most popular airlines that fly to San Diego from Michigan according to our data. Delta is the first choice among our users, with 40% of people opting to fly with this airline when traveling to San Diego. Keep in mind that there are 9 different airlines that fly to San Diego on a routine basis, so you have a few additional options to choose from.

The number of flights available between Michigan and San Diego is 42 per day as of May 2026. The most frequent departure time is 4:00PM, with 67% of daily flights leaving in the afternoon.

294 flights are operational weekly from Michigan to San Diego as of May 2026. The most popular departure day for this route is Sun, with 20% of flights per week taking off on this day.