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Cheap flights from Medford to Los Angeles from $73

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Medford to Los Angeles departing on 1/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Medford to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
4:07 pm - 6:08 pmMFR-SNA
2h 01mnonstop
Allegiant Air Logo
6:58 pm - 9:06 pmSNA-MFR
2h 08mnonstop
$135Allegiant Air
Find Deal
Sun, Dec 7 - Thu, Dec 11
Allegiant Air Logo
4:07 pm - 6:08 pmMFR-SNA
2h 01mnonstop
Allegiant Air Logo
6:58 pm - 9:06 pmSNA-MFR
2h 08mnonstop
$138Allegiant Air
Find Deal
Sun, Dec 7 - Thu, Dec 11
Multiple Airlines Logo
9:56 pm - 5:39 pmMFR-SNA
19h 43m1 stop
Multiple Airlines Logo
6:58 pm - 9:06 pmSNA-MFR
2h 08mnonstop
$161Multiple Airlines
Find Deal
Sun, Dec 7 - Thu, Dec 11
Multiple Airlines Logo
9:56 pm - 5:39 pmMFR-SNA
19h 43m1 stop
Multiple Airlines Logo
6:58 pm - 9:06 pmSNA-MFR
2h 08mnonstop
$166Multiple Airlines
Find Deal
Sun, Dec 7 - Thu, Dec 11
American Airlines Logo
5:32 am - 12:34 pmMFR-SNA
7h 02m1 stop
American Airlines Logo
12:38 pm - 7:38 pmSNA-MFR
7h 00m1 stop
$201American Airlines
Find Deal
Wed, Jan 7 - Wed, Jan 14
American Airlines Logo
2:27 pm - 9:49 pmMFR-SNA
7h 22m1 stop
American Airlines Logo
12:38 pm - 7:38 pmSNA-MFR
7h 00m1 stop
$241American Airlines
Find Deal
Thu, Jan 8 - Tue, Jan 13
Alaska Airlines Logo
1:30 pm - 9:14 pmMFR-SNA
7h 44m1 stop
Alaska Airlines Logo
2:00 pm - 7:36 pmSNA-MFR
5h 36m1 stop
$258Alaska Airlines
Find Deal
Sat, Dec 6 - Tue, Dec 9
Alaska Airlines Logo
1:30 pm - 9:14 pmMFR-SNA
7h 44m1 stop
Alaska Airlines Logo
6:45 am - 5:03 pmSNA-MFR
10h 18m2 stops
$287Alaska Airlines
Find Deal
Sat, Dec 6 - Tue, Dec 9
Delta Logo
6:00 am - 2:14 pmMFR-SNA
8h 14m1 stop
Delta Logo
3:10 pm - 11:32 pmSNA-MFR
8h 22m1 stop
$332Delta
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Thu, Nov 20 - Sat, Nov 22
Delta Logo
5:00 am - 12:17 pmMFR-SNA
7h 17m1 stop
Delta Logo
5:20 pm - 11:56 pmSNA-MFR
6h 36m1 stop
$379Delta
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Thu, Nov 20 - Mon, Nov 24

Alaska Airlines flights from Medford to Santa Ana, California

Our best Alaska Airlines deals on Medford to Santa Ana, California flight tickets
Alaska Airlines
Dec 6
MFR1:30 pmMedford
7h 44m
1 stop
SNA9:14 pmSanta Ana J. Wayne/Orange Cnty
Dec 9
SNA2:00 pmSanta Ana J. Wayne/Orange Cnty
5h 36m
1 stop
MFR7:36 pmMedford
$258
Find similar
Alaska Airlines
Dec 6
MFR1:30 pmMedford
7h 44m
1 stop
SNA9:14 pmSanta Ana J. Wayne/Orange Cnty
Dec 9
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
10h 18m
2 stops
MFR5:03 pmMedford
$287
Find similar
Alaska Airlines
Jan 2
MFR3:47 pmMedford
4h 35m
1 stop
SNA8:22 pmSanta Ana J. Wayne/Orange Cnty
Jan 7
SNA7:00 amSanta Ana J. Wayne/Orange Cnty
4h 57m
1 stop
MFR11:57 amMedford
$291
Find similar

Delta flights from Medford to Santa Ana, California

Our best Delta deals on Medford to Santa Ana, California flight tickets
Delta
Nov 20
MFR6:00 amMedford
8h 14m
1 stop
SNA2:14 pmSanta Ana J. Wayne/Orange Cnty
Nov 22
SNA3:10 pmSanta Ana J. Wayne/Orange Cnty
8h 22m
1 stop
MFR11:32 pmMedford
$332
Find similar
Delta
Nov 20
MFR5:00 amMedford
7h 17m
1 stop
SNA12:17 pmSanta Ana J. Wayne/Orange Cnty
Nov 24
SNA5:20 pmSanta Ana J. Wayne/Orange Cnty
6h 36m
1 stop
MFR11:56 pmMedford
$379
Find similar
Delta
Oct 31
MFR6:00 amMedford
8h 15m
1 stop
SNA2:15 pmSanta Ana J. Wayne/Orange Cnty
Nov 2
SNA5:10 pmSanta Ana J. Wayne/Orange Cnty
6h 39m
1 stop
MFR11:49 pmMedford
$388
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Medford to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from Medford to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MedfordSanta Ana

MFR - SNA

MFRSNA

Medford

Sun 12/7

4:07 pm-6:08 pm

Nonstop2h 01m

Santa Ana J. Wayne/Orange Cnty

Thu 12/11

6:58 pm-9:06 pm

Nonstop2h 08m

$135

MedfordSanta Ana

MFR - SNA

MFRSNA

Medford

Sun 12/7

4:07 pm-6:08 pm

Nonstop2h 01m

Santa Ana J. Wayne/Orange Cnty

Thu 12/11

6:58 pm-9:06 pm

Nonstop2h 08m

$138

MedfordSanta Ana

MFR - SNA

MFRSNA

Medford

Sun 12/7

9:56 pm-5:39 pm

1 stop19h 43m

Santa Ana J. Wayne/Orange Cnty

Thu 12/11

6:58 pm-9:06 pm

Nonstop2h 08m

$161

MedfordSanta Ana

MFR - SNA

MFRSNA

Medford

Sun 12/7

9:56 pm-5:39 pm

1 stop19h 43m

Santa Ana J. Wayne/Orange Cnty

Thu 12/11

6:58 pm-9:06 pm

Nonstop2h 08m

$166

MedfordSanta Ana

MFR - SNA

MFRSNA

Medford

Wed 1/7

5:32 am-12:34 pm

1 stop7h 02m

Santa Ana J. Wayne/Orange Cnty

Wed 1/14

12:38 pm-7:38 pm

1 stop7h 00m

$201

MedfordSanta Ana

MFR - SNA

MFRSNA

Medford

Thu 1/8

2:27 pm-9:49 pm

1 stop7h 22m

Santa Ana J. Wayne/Orange Cnty

Tue 1/13

12:38 pm-7:38 pm

1 stop7h 00m

$241

MedfordSanta Ana

MFR - SNA

MFRSNA

Medford

Sat 12/6

1:30 pm-9:14 pm

1 stop7h 44m

Santa Ana J. Wayne/Orange Cnty

Tue 12/9

2:00 pm-7:36 pm

1 stop5h 36m

$258

MedfordSanta Ana

MFR - SNA

MFRSNA

Medford

Sat 12/6

1:30 pm-9:14 pm

1 stop7h 44m

Santa Ana J. Wayne/Orange Cnty

Tue 12/9

6:45 am-5:03 pm

2 stops10h 18m

$287

MedfordSanta Ana

MFR - SNA

MFRSNA

Medford

Thu 11/20

6:00 am-2:14 pm

1 stop8h 14m

Santa Ana J. Wayne/Orange Cnty

Sat 11/22

3:10 pm-11:32 pm

1 stop8h 22m

$332

MedfordSanta Ana

MFR - SNA

MFRSNA

Medford

Thu 11/20

5:00 am-12:17 pm

1 stop7h 17m

Santa Ana J. Wayne/Orange Cnty

Mon 11/24

5:20 pm-11:56 pm

1 stop6h 36m

$379

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Medford to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana, California?

In general, May is the cheapest month to fly from Medford to Santa Ana, California. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $159. If you aren’t able to travel during the month of May, then book flights to Santa Ana, California from Medford during March instead. Flights to Santa Ana, California in March, while not as cheap as those in May, still average around $165.

What is the cheapest day to depart on your flight to Santa Ana, California?

The cheapest day to depart from Medford to Santa Ana, California is on a Saturday. Travelers who choose to depart for Santa Ana, California on a Saturday will often find tickets for as low as $155. The most expensive day to fly to Santa Ana, California is Tuesday, with ticket prices averaging around $272.

What is the cheapest time of day to depart on your flight to Santa Ana, California?

In the afternoon is the cheapest time of day to fly from Medford to Santa Ana, California when you can find flight prices for as low as $164. Flying to Santa Ana, California in the afternoon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Santa Ana, California is in the morning when prices are around $200.

What is the cheapest Medford to Santa Ana J. Wayne/Orange Cnty flight route?

Fly from Medford to Santa Ana J. Wayne/Orange Cnty for the best Medford - Santa Ana J. Wayne/Orange Cnty flight prices

How far in advance should I book a flight to Santa Ana, California?

You are more likely to see cheaper flights to Santa Ana, California from Medford when booking weeks ahead of your departure date. In general, you can expect to find flights to Santa Ana, California for around $275 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santa Ana, California from Medford for as low as $154 on momondo.

What cabin class options are available on Medford to Santa Ana J. Wayne/Orange Cnty flights?

There is only 1 cabin class available to choose from on Medford to Santa Ana J. Wayne/Orange Cnty flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Medford to Santa Ana, California flights?

No. A direct flight is the cheapest option for a flight between Medford to Santa Ana, California.

How have Medford to Santa Ana, California flight prices changed over time?

As of October 2025, prices for Medford to Santa Ana, California flights are approximately 32% more expensive when compared to flights at the same time last year.

When to book flights from Medford to Santa Ana, California

Are you open to changing your travel dates? Check out the ideal times to fly from Medford to Santa Ana, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Medford to Santa Ana, California (MFR to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Medford to Santa Ana, California

Best Price Found

$87

Fastest flight time

1h 59m

Direct flights

Mon, Wed, Fri and Sat

Airports in Santa Ana, California

1 airport
The best one-way flight to Santa Ana, California from Medford in the past 72 hours is $87. The best round-trip flight deal from Medford to Santa Ana, California found on momondo in the last 72 hours is $160.
The fastest flight from Medford to Santa Ana, California takes 1h 59m
Direct flights go from Medford to Santa Ana, California on Monday, Wednesday, Friday and Saturday. The only airline offering direct flights is Allegiant Air.
There is 1 airport near Santa Ana, California: Santa Ana J. Wayne/Orange Cnty (SNA)
Search flight deals

  • How far is Medford to Santa Ana J. Wayne/Orange Cnty by plane?

    The distance between Medford and Santa Ana J. Wayne/Orange Cnty is about 651.7 mi. 2h 01m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Medford Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Medford Airport to Santa Ana J. Wayne/Orange Cnty Airport were last updated today.

  • How many operators does momondo search for flights from Medford Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Medford Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Medford Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The necessary travel and health documents for your Santa Ana J. Wayne/Orange Cnty Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Medford to Santa Ana, California?

  • What is the most popular airline from Medford to Santa Ana, California?

Best airlines flying from Medford to Santa Ana, California

Compare and see reviews for airlines that fly from Medford to Santa Ana, California with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $94Free CancellationRating
7.2
695 reviews
Search Allegiant Air flights
DeltaPriceFrom $183Free CancellationRating
7.9
7,994 reviews
Search Delta flights
United AirlinesPriceFrom $240Free CancellationRating
7.4
9,000 reviews
Search United Airlines flights
Alaska AirlinesPriceFrom $250Free CancellationRating
8.0
11,201 reviews
Search Alaska Airlines flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from Medford to Santa Ana?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Medford to Santa Ana. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Medford to Santa Ana with flexible booking policies on momondo?

Flights from Medford to Santa Ana with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Medford to Santa Ana?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Medford to Santa Ana.

I’m not ready to book a flight from Medford to Santa Ana right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Medford to Santa Ana flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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