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Cheap flights from Medford to San Diego from $84

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Medford to San Diego departing on 2/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Medford to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
Alaska Airlines Logo
1:20 pm - 3:21 pm
MFR
-
SAN
2h 01mnonstop
Alaska Airlines Logo
10:22 am - 12:45 pm
SAN
-
MFR
2h 23mnonstop
$137Alaska Airlines
Sat, Feb 7 - Tue, Feb 10
Delta Logo
3:00 pm - 8:43 pm
MFR
-
SAN
5h 43m
1 stop
Delta Logo
7:03 pm - 11:48 pm
SAN
-
MFR
4h 45m
1 stop
$147Delta
Sat, Feb 7 - Tue, Feb 10
Alaska Airlines Logo
7:40 am - 9:54 am
MFR
-
SAN
2h 14mnonstop
Alaska Airlines Logo
6:45 pm - 9:02 pm
SAN
-
MFR
2h 17mnonstop
$157Alaska Airlines
Thu, Apr 9 - Sat, Apr 11
Delta Logo
5:20 pm - 10:42 pm
MFR
-
SAN
5h 22m
1 stop
Delta Logo
3:25 pm - 11:12 pm
SAN
-
MFR
7h 47m
1 stop
$167Delta
Tue, Feb 10 - Tue, Feb 17
Alaska Airlines Logo
1:22 pm - 8:58 pm
MFR
-
SAN
7h 36m
1 stop
Alaska Airlines Logo
10:29 am - 12:43 pm
SAN
-
MFR
2h 14mnonstop
$177Alaska Airlines
Tue, Feb 10 - Tue, Feb 17
Delta Logo
11:30 am - 5:50 pm
MFR
-
SAN
6h 20m
1 stop
Delta Logo
3:25 pm - 11:12 pm
SAN
-
MFR
7h 47m
1 stop
$187Delta
Fri, Feb 27 - Thu, Mar 5
United Airlines Logo
5:02 am - 5:29 pm
MFR
-
SAN
12h 27m
2 stops
United Airlines Logo
6:15 am - 10:56 am
SAN
-
MFR
4h 41m
1 stop
$192United Airlines
Tue, Feb 24 - Thu, Feb 26
United Airlines Logo
2:00 pm - 11:42 pm
MFR
-
SAN
9h 42m
2 stops
United Airlines Logo
11:08 am - 9:02 pm
SAN
-
MFR
9h 54m
2 stops
$193United Airlines
Tue, Feb 10 - Wed, Feb 11
Alaska Airlines Logo
5:44 pm - 11:03 pm
MFR
-
SAN
5h 19m
1 stop
Alaska Airlines Logo
10:19 am - 12:33 pm
SAN
-
MFR
2h 14mnonstop
$197Alaska Airlines
Tue, Feb 24 - Thu, Feb 26
United Airlines Logo
5:02 am - 5:29 pm
MFR
-
SAN
12h 27m
2 stops
United Airlines Logo
11:05 am - 9:18 pm
SAN
-
MFR
10h 13m
2 stops
$198United Airlines
Tue, Feb 24 - Thu, Feb 26

Delta flights from Medford to San Diego

Our best Delta deals on Medford to San Diego flight tickets
Delta
Feb 24
MFR11:30 amMedford
6h 20m
1 stop
SAN5:50 pmSan Diego
Feb 28
SAN5:20 pmSan Diego
5h 52m
1 stop
MFR11:12 pmMedford
$147
Delta
Feb 10
MFR5:20 pmMedford
5h 22m
1 stop
SAN10:42 pmSan Diego
Feb 17
SAN3:25 pmSan Diego
7h 47m
1 stop
MFR11:12 pmMedford
$167
Delta
Feb 27
MFR11:30 amMedford
6h 20m
1 stop
SAN5:50 pmSan Diego
Mar 5
SAN3:25 pmSan Diego
7h 47m
1 stop
MFR11:12 pmMedford
$187

Alaska Airlines flights from Medford to San Diego

Our best Alaska Airlines deals on Medford to San Diego flight tickets
Alaska Airlines
Feb 7
MFR1:20 pmMedford
2h 01m
SAN3:21 pmSan Diego
Feb 10
SAN10:22 amSan Diego
2h 23m
MFR12:45 pmMedford
$137
Alaska Airlines
Apr 9
MFR7:40 amMedford
2h 14m
SAN9:54 amSan Diego
Apr 11
SAN6:45 pmSan Diego
2h 17m
MFR9:02 pmMedford
$157
Alaska Airlines
Feb 10
MFR1:22 pmMedford
7h 36m
1 stop
SAN8:58 pmSan Diego
Feb 11
SAN10:22 amSan Diego
2h 23m
MFR12:45 pmMedford
$177

momondo Fare Finder

 
Customize your flight search to find flights from Medford to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 18, 2026.
Use the filters below to find and compare flights from Medford to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Sat 2/7

1:20 pm-3:21 pm

Nonstop2h 01m

San Diego

Tue 2/10

10:22 am-12:45 pm

Nonstop2h 23m

$137

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Sat 2/7

3:00 pm-8:43 pm

1 stop5h 43m

San Diego

Tue 2/10

7:03 pm-11:48 pm

1 stop4h 45m

$147

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Thu 4/9

7:40 am-9:54 am

Nonstop2h 14m

San Diego

Sat 4/11

6:45 pm-9:02 pm

Nonstop2h 17m

$157

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Tue 2/10

5:20 pm-10:42 pm

1 stop5h 22m

San Diego

Tue 2/17

3:25 pm-11:12 pm

1 stop7h 47m

$167

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Tue 2/10

1:22 pm-8:58 pm

1 stop7h 36m

San Diego

Tue 2/17

10:29 am-12:43 pm

Nonstop2h 14m

$177

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Fri 2/27

11:30 am-5:50 pm

1 stop6h 20m

San Diego

Thu 3/5

3:25 pm-11:12 pm

1 stop7h 47m

$187

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Tue 2/24

5:02 am-5:29 pm

2 stops12h 27m

San Diego

Thu 2/26

6:15 am-10:56 am

1 stop4h 41m

$192

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Tue 2/10

2:00 pm-11:42 pm

2 stops9h 42m

San Diego

Wed 2/11

11:08 am-9:02 pm

2 stops9h 54m

$193

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Tue 2/24

5:44 pm-11:03 pm

1 stop5h 19m

San Diego

Thu 2/26

10:19 am-12:33 pm

Nonstop2h 14m

$197

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Tue 2/24

5:02 am-5:29 pm

2 stops12h 27m

San Diego

Thu 2/26

11:05 am-9:18 pm

2 stops10h 13m

$198

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Medford to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Medford and San Diego?

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of June, then departing from Medford during the month July is also very affordable. Most momondo users find prices during this month for around $217.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Medford to San Diego is on a Sunday. Travelers who choose to depart for San Diego on a Sunday will often find tickets for as low as $170. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $317. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is in the afternoon when flights can be purchased for as low as $237. Flights at noon are often more expensive with an average ticket price of $366.

What is the cheapest Medford to San Diego flight route?

Fly from Medford to San Diego for the best Medford - San Diego flight prices

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Medford when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $285 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Medford for as low as $219 on momondo.

What cabin class options are available on Medford to San Diego flights?

There are 4 cabin classes available to choose from on Medford to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Medford to San Diego flights?

You could potentially save up to 32% on your flight if you consider stops on a Medford to San Diego flight.

How have Medford to San Diego flight prices changed over time?

As of January 2026, prices for Medford to San Diego flights are approximately 43% cheaper when compared to flights at the same time last year.

When to book flights from Medford to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Medford to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Medford to San Diego (MFR to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Medford to San Diego

Best Price Found

$114

Fastest flight time

2h 07m

Direct flights

Every day

Airports in San Diego

1 airport
The best one-way flight to San Diego from Medford in the past 72 hours is $114. The best round-trip flight deal from Medford to San Diego found on momondo in the last 72 hours is $157.
The fastest flight from Medford to San Diego takes 2h 07m
Direct flights go from Medford to San Diego every day.
There is 1 airport in San Diego. From Medford there are direct flights to San Diego (SAN).
Search flight deals

  • How far is Medford to San Diego by plane?

    Medford and San Diego are 733.3 mi apart from one another. Typically, this will take 2h 07m by plane in normal conditions.

  • When did momondo last update prices for flights from Medford Airport to San Diego Airport?

    Prices for flights from Medford Airport to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Medford Airport to San Diego Airport?

  • How old do you have to be to fly from Medford Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Medford Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The travel and health documents required for your trip to San Diego Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at San Diego Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Medford to San Diego?

  • What is the most popular airline from Medford to San Diego?

Best airlines flying from Medford to San Diego

Compare and see reviews for airlines that fly from Medford to San Diego with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $52Free CancellationRating
7.2
704 reviews
Search Allegiant Air flights
Hawaiian AirlinesPriceFrom $118Free CancellationRating
7.8
2,829 reviews
Search Hawaiian Airlines flights
DeltaPriceFrom $153Free CancellationRating
7.9
8,075 reviews
Search Delta flights
Alaska AirlinesPriceFrom $161Free CancellationRating
8.0
11,746 reviews
Search Alaska Airlines flights
United AirlinesPriceFrom $216Free CancellationRating
7.4
9,177 reviews
Search United Airlines flights

  • Alaska Airlines Flights From Medford to San Diego

    Alaska Airlines operates around 7 flights from Medford to San Diego every week. The average price of these flights found in the last 72 hours has been $289, but momondo users have found Alaska Airlines deals from Medford to San Diego from as low as $161 round-trip. Alaska Airlines has been scored 8.0/10 in 11,746 reviews.

  • Hawaiian Airlines Flights From Medford to San Diego

    $118 is the best Hawaiian Airlines flight deal from Medford to San Diego found on momondo over the last 72 hours. The average Hawaiian Airlines ticket price found was closer to $252, however, with flight time and availability significantly affecting the price. Hawaiian Airlines (7.8/10 from 2,829 user reviews) flies into San Diego from Medford 7 times in an average week so prices can vary.

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
Poway
National City
Imperial Beach
Borrego Springs
San Ysidro
La Mesa
Alpine
Lemon Grove
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Medford to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Medford to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Medford to San Diego with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Medford to San Diego flights to just show those with flexible booking policies.

How can momondo help me find flights from Medford to San Diego?

momondo provides multiple filters to help you find the best flight to San Diego from Medford. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Medford to San Diego right now. Can momondo alert me if prices change?

If you are simply researching potential flights to San Diego, momondo offers a useful price alert feature which will track prices for flights to San Diego from Medford and alert you when they change.

An easier way to manage your San Diego trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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