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Cheap flights from Medford to San Diego from $74

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Medford to San Diego departing on 1/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

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Alaska Airlines Logo
1:20 pm - 3:21 pm
MFR
-
SAN
2h 01mnonstop
Alaska Airlines Logo
10:22 am - 12:45 pm
SAN
-
MFR
2h 23mnonstop
$96Alaska Airlines
Tue, Jan 27 - Sat, Jan 31
Alaska Airlines Logo
1:20 pm - 3:21 pm
MFR
-
SAN
2h 01mnonstop
Alaska Airlines Logo
10:22 am - 12:45 pm
SAN
-
MFR
2h 23mnonstop
$97Alaska Airlines
Sat, Jan 24 - Sat, Jan 31
Alaska Airlines Logo
1:20 pm - 3:21 pm
MFR
-
SAN
2h 01mnonstop
Alaska Airlines Logo
10:22 am - 12:45 pm
SAN
-
MFR
2h 23mnonstop
$107Alaska Airlines
Sat, Jan 24 - Mon, Jan 26
Hawaiian Airlines Logo
5:42 am - 1:19 pm
MFR
-
SAN
7h 37m1 stop
Hawaiian Airlines Logo
10:22 am - 12:45 pm
SAN
-
MFR
2h 23mnonstop
$127Hawaiian Airlines
Tue, Jan 27 - Sat, Jan 31
Alaska Airlines Logo
1:20 pm - 3:21 pm
MFR
-
SAN
2h 01mnonstop
Alaska Airlines Logo
6:15 am - 5:02 pm
SAN
-
MFR
10h 47m1 stop
$132Alaska Airlines
Sat, Jan 24 - Sat, Jan 31
Delta Logo
11:30 am - 5:50 pm
MFR
-
SAN
6h 20m1 stop
Delta Logo
7:01 pm - 11:46 pm
SAN
-
MFR
4h 45m1 stop
$137Delta
Fri, Feb 27 - Thu, Mar 5
Alaska Airlines Logo
1:10 pm - 3:17 pm
MFR
-
SAN
2h 07mnonstop
Alaska Airlines Logo
7:50 am - 5:07 pm
SAN
-
MFR
9h 17m1 stop
$142Alaska Airlines
Fri, Feb 27 - Thu, Mar 5
Alaska Airlines Logo
12:39 pm - 8:11 pm
MFR
-
SAN
7h 32m1 stop
Alaska Airlines Logo
6:15 am - 12:43 pm
SAN
-
MFR
6h 28m1 stop
$156Alaska Airlines
Tue, Jan 27 - Sat, Jan 31
Delta Logo
3:20 pm - 10:20 pm
MFR
-
SAN
7h 00m1 stop
Delta Logo
7:01 pm - 11:46 pm
SAN
-
MFR
4h 45m1 stop
$157Delta
Sat, Feb 14 - Tue, Feb 17
American Airlines Logo
5:32 am - 11:44 am
MFR
-
SAN
6h 12m1 stop
American Airlines Logo
12:46 pm - 7:38 pm
SAN
-
MFR
6h 52m1 stop
$158American Airlines
Sat, Jan 24 - Sat, Jan 31

Hawaiian Airlines flights from Medford to San Diego

Our best Hawaiian Airlines deals on Medford to San Diego flight tickets
Hawaiian Airlines
Jan 27
MFR5:42 amMedford
7h 37m
1 stop
SAN1:19 pmSan Diego
Jan 31
SAN10:22 amSan Diego
2h 23m
MFR12:45 pmMedford
$127
Find similar
Hawaiian Airlines
Jan 30
MFR1:20 pmMedford
2h 01m
SAN3:21 pmSan Diego
Feb 2
SAN10:55 amSan Diego
5h 13m
1 stop
MFR4:08 pmMedford
$237
Find similar

American Airlines flights from Medford to San Diego

Our best American Airlines deals on Medford to San Diego flight tickets
American Airlines
Jan 24
MFR5:32 amMedford
6h 12m
1 stop
SAN11:44 amSan Diego
Jan 31
SAN12:46 pmSan Diego
6h 52m
1 stop
MFR7:38 pmMedford
$158
Find similar
American Airlines
Jan 16
MFR3:00 pmMedford
6h 58m
1 stop
SAN9:58 pmSan Diego
Jan 19
SAN10:09 amSan Diego
7h 19m
1 stop
MFR5:28 pmMedford
$209
Find similar
American Airlines
Dec 12
MFR5:20 amMedford
6h 37m
1 stop
SAN11:57 amSan Diego
Dec 14
SAN12:50 pmSan Diego
7h 21m
1 stop
MFR8:11 pmMedford
$536
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Medford to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Medford to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Tue 1/27

1:20 pm-3:21 pm

Nonstop2h 01m

San Diego

Sat 1/31

10:22 am-12:45 pm

Nonstop2h 23m

$96

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Sat 1/24

1:20 pm-3:21 pm

Nonstop2h 01m

San Diego

Sat 1/31

10:22 am-12:45 pm

Nonstop2h 23m

$97

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Sat 1/24

1:20 pm-3:21 pm

Nonstop2h 01m

San Diego

Mon 1/26

10:22 am-12:45 pm

Nonstop2h 23m

$107

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Tue 1/27

5:42 am-1:19 pm

1 stop7h 37m

San Diego

Sat 1/31

10:22 am-12:45 pm

Nonstop2h 23m

$127

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Sat 1/24

1:20 pm-3:21 pm

Nonstop2h 01m

San Diego

Sat 1/31

6:15 am-5:02 pm

1 stop10h 47m

$132

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Fri 2/27

11:30 am-5:50 pm

1 stop6h 20m

San Diego

Thu 3/5

7:01 pm-11:46 pm

1 stop4h 45m

$137

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Fri 2/27

1:10 pm-3:17 pm

Nonstop2h 07m

San Diego

Thu 3/5

7:50 am-5:07 pm

1 stop9h 17m

$142

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Tue 1/27

12:39 pm-8:11 pm

1 stop7h 32m

San Diego

Sat 1/31

6:15 am-12:43 pm

1 stop6h 28m

$156

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Sat 2/14

3:20 pm-10:20 pm

1 stop7h 00m

San Diego

Tue 2/17

7:01 pm-11:46 pm

1 stop4h 45m

$157

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Sat 1/24

5:32 am-11:44 am

1 stop6h 12m

San Diego

Sat 1/31

12:46 pm-7:38 pm

1 stop6h 52m

$158

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Medford to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of June, then departing from Medford during the month July is also very affordable. Most momondo users find prices during this month for around $219.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Medford to San Diego is on a Sunday. Travelers who choose to depart for San Diego on a Sunday will often find tickets for as low as $170. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $298. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is in the afternoon when flights can be purchased for as low as $237. Flights at noon are often more expensive with an average ticket price of $367.

What is the cheapest Medford to San Diego flight route?

Fly from Medford to San Diego for the best Medford - San Diego flight prices

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Medford when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $298 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Medford for as low as $195 on momondo.

What cabin class options are available on Medford to San Diego flights?

There are 4 cabin classes available to choose from on Medford to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Medford to San Diego flight prices changed over time?

As of December 2025, prices for Medford to San Diego flights are approximately 29% cheaper when compared to flights at the same time last year.

When to book flights from Medford to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Medford to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Medford to San Diego (MFR to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Medford to San Diego

Best Price Found

$143

Fastest flight time

2h 01m

Direct flights

Every day

Airports in San Diego

1 airport
The best one-way flight to San Diego from Medford in the past 72 hours is $143. The best round-trip flight deal from Medford to San Diego found on momondo in the last 72 hours is $217.
The fastest flight from Medford to San Diego takes 2h 01m
Direct flights go from Medford to San Diego every day.
There is 1 airport near San Diego: San Diego (SAN)
Search flight deals

  • How far is Medford to San Diego by plane?

    Medford and San Diego are 733.3 mi apart from one another. Typically, this will take 2h 01m by plane in normal conditions.

  • When did momondo last update prices for flights from Medford Airport to San Diego Airport?

    Prices for flights from Medford Airport to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Medford Airport to San Diego Airport?

  • How old do you have to be to fly from Medford Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Medford Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The travel and health documents required for your trip to San Diego Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at San Diego Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Medford to San Diego?

  • What is the most popular airline from Medford to San Diego?

Best airlines flying from Medford to San Diego

Compare and see reviews for airlines that fly from Medford to San Diego with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $54Free CancellationRating
7.2
698 reviews
Search Allegiant Air flights
Hawaiian AirlinesPriceFrom $131Free CancellationRating
7.8
2,817 reviews
Search Hawaiian Airlines flights
DeltaPriceFrom $153Free CancellationRating
7.9
8,011 reviews
Search Delta flights
Alaska AirlinesPriceFrom $177Free CancellationRating
8.0
11,402 reviews
Search Alaska Airlines flights
United AirlinesPriceFrom $224Free CancellationRating
7.4
9,066 reviews
Search United Airlines flights

  • Alaska Airlines Flights From Medford to San Diego

    Alaska Airlines operates around 7 flights from Medford to San Diego every week. The average price of these flights found in the last 72 hours has been $296, but momondo users have found Alaska Airlines deals from Medford to San Diego from as low as $177 round-trip. Alaska Airlines has been scored 8.0/10 in 11,402 reviews.

  • Hawaiian Airlines Flights From Medford to San Diego

    $131 is the best Hawaiian Airlines flight deal from Medford to San Diego found on momondo over the last 72 hours. The average Hawaiian Airlines ticket price found was closer to $257, however, with flight time and availability significantly affecting the price. Hawaiian Airlines (7.8/10 from 2,817 user reviews) flies into San Diego from Medford 7 times in an average week so prices can vary.

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
Imperial Beach
Poway
La Mesa
Borrego Springs
San Ysidro
Lemon Grove
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Medford to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Medford to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Medford to San Diego with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Medford to San Diego flights to just show those with flexible booking policies.

How can momondo help me find flights from Medford to San Diego?

momondo provides multiple filters to help you find the best flight to San Diego from Medford. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Medford to San Diego right now. Can momondo alert me if prices change?

If you are simply researching potential flights to San Diego, momondo offers a useful price alert feature which will track prices for flights to San Diego from Medford and alert you when they change.

An easier way to manage your San Diego trip

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