Cheap flights from Medford to San Diego from $109

If you are unable to visit San Diego during the month of February, then departing from Medford during the month January is also very affordable. Most momondo users find prices during this month for around $227.

The cheapest day to depart from Medford to San Diego is on a Thursday. Travelers who choose to depart for San Diego on a Thursday will often find tickets for as low as $277. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $387. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

The cheapest time of day to fly to San Diego is in the afternoon when flights can be purchased for as low as $238. Flights in the morning are often more expensive with an average ticket price of $374.

Fly from Medford to San Diego for the best Medford - San Diego flight prices

You are more likely to see cheaper flights to San Diego from Medford when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $273 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Medford for as low as $183 on momondo.

There are 4 cabin classes available to choose from on Medford to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 24% on your flight if you consider stops on a Medford to San Diego flight.

As of June 2026, prices for Medford to San Diego flights are approximately 8% more expensive when compared to flights at the same time last year.

United Airlines is the most popular carrier operating from Medford to San Diego

Alaska Airlines, United Airlines and Allegiant Air are the top three most popular airlines that fly to San Diego from Medford according to our data. Alaska Airlines is the first choice among our users, with 49% of people opting to fly with this airline when traveling to San Diego. Keep in mind that there are 5 different airlines that fly to San Diego on a routine basis, so you have a few additional options to choose from.

The number of flights available between Medford and San Diego is 1 per day as of June 2026. The most frequent departure time is 7:00AM, with 100% of daily flights leaving at noon.

As of June 2026, 7 flights take off from Medford and land in San Diego each week. The most common flight departure day for this route is Mon, with 14% of weekly flights taking off on this day.