Cheap flights from Madrid to San Francisco from $372

If you aren’t able to travel to San Francisco during the month of February, then flying in October is also cheap. Prices for this month can be found on momondo for an average of $568.

The cheapest day to depart from Madrid to San Francisco is on a Tuesday when prices can be found for as low as $686. The most expensive day to fly to San Francisco is Thursday, with ticket prices averaging around $1,382.

Fly from Madrid Barajas to San Francisco for the best Madrid Barajas - San Francisco flight prices

You are more likely to see cheaper flights to San Francisco from Madrid when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $686 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Madrid for as low as $602 on momondo.

There are 3 cabin classes available to choose from on Madrid to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

No. A direct flight is the cheapest option for a flight between Madrid to San Francisco.

British Airways is the most popular carrier operating from Madrid Barajas to San Francisco

Iberia, British Airways and TAP AIR PORTUGAL are the top three most popular airlines that fly to San Francisco from Madrid according to our data. Iberia is the first choice among our users, with 46% of people opting to fly with this airline when traveling to San Francisco. Keep in mind that there are 10 different airlines that fly to San Francisco on a routine basis, so you have a few additional options to choose from.

Historically, on average around 12% of flights between Madrid and San Francisco have experienced a delay on any given week. The average delay length over the past 12 months has been 192 minutes.

Generally, flights departing in the morning tend to experience fewer delays. Flights in the early afternoon have, in the past, seen delays more frequently in comparison.

Wednesday is statistically the day of the week which experiences the fewest number of delays on this flight route. Saturday has historically seen more delays on average compared to the rest of the week.

According to our data, Iberia have had the least number of delays on this route over the last 12 months; with about 12% of their flights experiencing any sort of delay.

Zurich (ZRH) was the most common stop: 20% of momondo users choosing 1-stop flights on this route connected there.

Flights via Paris (CDG) offer the lowest average round-trip price of $516.

Flights connecting via Amsterdam (AMS) have the shortest average one-way travel time: 14h 50m.

Zurich (ZRH) has the shortest average layover time for this route: 0h 50m.

As of April 2026, 2 flights take off from Madrid and land in San Francisco each day. The most common flight departure time for this route is 12:00PM, with 100% of daily flights taking off in the afternoon.

As of April 2026, there are 18 flights per week flying from Madrid to San Francisco. The most common day of the week flights depart is Tue, with 33% of flights taking off on this day.