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Cheap flights from Louisville to San Antonio from $128

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to San Antonio departing on 9/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Louisville to San Antonio

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
2:55 pm - 8:20 pmSDF  Louisville Intl-SAT San Antonio
6h 25m1 stop Denver Intl
Southwest Logo
3:25 pm - 8:35 pmSAT  San Antonio-SDF Louisville Intl
4h 10m1 stop Nashville Intl
$227Southwest
Sat, Sep 5 - Fri, Sep 11
Southwest Logo
2:55 pm - 8:20 pmSDF  Louisville Intl-SAT San Antonio
6h 25m1 stop Denver Intl
Southwest Logo
6:00 am - 1:05 pmSAT  San Antonio-SDF Louisville Intl
6h 05m2 stops Houston Hobby Nashville Intl
$232Southwest
Sat, Sep 5 - Fri, Sep 11
American Airlines Logo
5:59 pm - 9:59 pmSDF  Louisville Intl-SAT San Antonio
5h 00m1 stop Dallas/Fort Worth
American Airlines Logo
7:00 am - 3:28 pmSAT  San Antonio-SDF Louisville Intl
7h 28m1 stop Dallas/Fort Worth
$255American Airlines
Sat, Sep 26 - Sat, Oct 3
American Airlines Logo
3:36 pm - 10:56 pmSDF  Louisville Intl-SAT San Antonio
8h 20m1 stop Charlotte Douglas
American Airlines Logo
6:00 pm - 12:08 amSAT  San Antonio-SDF Louisville Intl
5h 08m1 stop Charlotte Douglas
$255American Airlines
Wed, Oct 21 - Mon, Oct 26
Delta Logo
5:55 pm - 12:08 amSDF  Louisville Intl-SAT San Antonio
7h 13m1 stop Atlanta Hartsfield-Jackson
Delta Logo
4:29 pm - 11:59 pmSAT  San Antonio-SDF Louisville Intl
6h 30m1 stop Atlanta Hartsfield-Jackson
$255Delta
Tue, Sep 29 - Wed, Oct 7
Delta Logo
3:25 pm - 9:04 pmSDF  Louisville Intl-SAT San Antonio
6h 39m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:10 pm - 11:59 pmSAT  San Antonio-SDF Louisville Intl
4h 49m1 stop Atlanta Hartsfield-Jackson
$255Delta
Sat, Sep 5 - Wed, Sep 9
United Airlines Logo
6:00 am - 11:04 amSDF  Louisville Intl-SAT San Antonio
6h 04m1 stop Washington, D.C. Dulles Intl
United Airlines Logo
5:30 pm - 11:59 pmSAT  San Antonio-SDF Louisville Intl
5h 29m1 stop Chicago O'Hare Intl
$289United Airlines
Wed, Oct 21 - Fri, Oct 23
United Airlines Logo
3:25 pm - 8:52 pmSDF  Louisville Intl-SAT San Antonio
6h 27m1 stop Denver Intl
United Airlines Logo
1:00 pm - 8:32 pmSAT  San Antonio-SDF Louisville Intl
6h 32m1 stop Chicago O'Hare Intl
$293United Airlines
Tue, Sep 8 - Thu, Sep 10
Multiple Airlines Logo
10:56 am - 8:45 amSDF  Louisville Intl-SAT San Antonio
22h 49m1 stop Raleigh-Durham
Multiple Airlines Logo
10:05 am - 10:11 amSAT  San Antonio-SDF Louisville Intl
23h 06m2 stops Orlando Raleigh-Durham
$301Multiple Airlines
Wed, Sep 9 - Fri, Sep 11
Multiple Airlines Logo
8:46 pm - 9:15 amSDF  Louisville Intl-SAT San Antonio
13h 29m1 stop Raleigh-Durham
Multiple Airlines Logo
10:05 am - 10:11 amSAT  San Antonio-SDF Louisville Intl
23h 06m2 stops Orlando Raleigh-Durham
$318Multiple Airlines
Sat, Sep 5 - Fri, Sep 11

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Southwest flights from Louisville to San Antonio

Our best Southwest deals on Louisville to San Antonio flight tickets
Southwest
Sep 5
SDF2:55 pmLouisville Intl
6h 25m
1 stop
SAT8:20 pmSan Antonio
Sep 11
SAT3:25 pmSan Antonio
4h 10m
1 stop
SDF8:35 pmLouisville Intl
$227
Southwest
Sep 5
SDF2:55 pmLouisville Intl
6h 25m
1 stop
SAT8:20 pmSan Antonio
Sep 11
SAT6:00 amSan Antonio
6h 05m
2 stops
SDF1:05 pmLouisville Intl
$232
Southwest
Sep 11
SDF7:10 pmLouisville Intl
5h 10m
1 stop
SAT11:20 pmSan Antonio
Sep 14
SAT2:55 pmSan Antonio
6h 45m
1 stop
SDF10:40 pmLouisville Intl
$241

Delta flights from Louisville to San Antonio

Our best Delta deals on Louisville to San Antonio flight tickets
Delta
Oct 7
SDF6:00 amLouisville Intl
4h 43m
1 stop
SAT9:43 amSan Antonio
Oct 10
SAT5:00 pmSan Antonio
5h 59m
1 stop
SDF11:59 pmLouisville Intl
$255
Delta
Oct 5
SDF7:55 pmLouisville Intl
5h 13m
1 stop
SAT12:08 amSan Antonio
Oct 13
SAT4:29 pmSan Antonio
6h 30m
1 stop
SDF11:59 pmLouisville Intl
$262
Delta
Sep 6
SDF5:50 pmLouisville Intl
5h 53m
1 stop
SAT10:43 pmSan Antonio
Sep 12
SAT5:00 pmSan Antonio
5h 59m
1 stop
SDF11:59 pmLouisville Intl
$263

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 14, 2026.
Use the filters below to find and compare flights from Louisville to San Antonio that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

LouisvilleSan Antonio

SDF Louisville Intl - SAT San Antonio

SDFSAT

Louisville Intl

Sat 9/5

2:55 pm-8:20 pm

1 stop6h 25m

San Antonio

Fri 9/11

3:25 pm-8:35 pm

1 stop4h 10m

$227

LouisvilleSan Antonio

SDF Louisville Intl - SAT San Antonio

SDFSAT

Louisville Intl

Sat 9/5

2:55 pm-8:20 pm

1 stop6h 25m

San Antonio

Fri 9/11

6:00 am-1:05 pm

2 stops6h 05m

$232

LouisvilleSan Antonio

SDF Louisville Intl - SAT San Antonio

SDFSAT

Louisville Intl

Sat 9/26

5:59 pm-9:59 pm

1 stop5h 00m

San Antonio

Sat 10/3

7:00 am-3:28 pm

1 stop7h 28m

$255

LouisvilleSan Antonio

SDF Louisville Intl - SAT San Antonio

SDFSAT

Louisville Intl

Wed 10/21

3:36 pm-10:56 pm

1 stop8h 20m

San Antonio

Mon 10/26

6:00 pm-12:08 am

1 stop5h 08m

$255

LouisvilleSan Antonio

SDF Louisville Intl - SAT San Antonio

SDFSAT

Louisville Intl

Tue 9/29

5:55 pm-12:08 am

1 stop7h 13m

San Antonio

Wed 10/7

4:29 pm-11:59 pm

1 stop6h 30m

$255

LouisvilleSan Antonio

SDF Louisville Intl - SAT San Antonio

SDFSAT

Louisville Intl

Sat 9/5

3:25 pm-9:04 pm

1 stop6h 39m

San Antonio

Wed 9/9

6:10 pm-11:59 pm

1 stop4h 49m

$255

LouisvilleSan Antonio

SDF Louisville Intl - SAT San Antonio

SDFSAT

Louisville Intl

Wed 10/21

6:00 am-11:04 am

1 stop6h 04m

San Antonio

Fri 10/23

5:30 pm-11:59 pm

1 stop5h 29m

$289

LouisvilleSan Antonio

SDF Louisville Intl - SAT San Antonio

SDFSAT

Louisville Intl

Tue 9/8

3:25 pm-8:52 pm

1 stop6h 27m

San Antonio

Thu 9/10

1:00 pm-8:32 pm

1 stop6h 32m

$293

LouisvilleSan Antonio

SDF Louisville Intl - SAT San Antonio

SDFSAT

Louisville Intl

Wed 9/9

10:56 am-8:45 am

1 stop22h 49m

San Antonio

Fri 9/11

10:05 am-10:11 am

2 stops23h 06m

$301

LouisvilleSan Antonio

SDF Louisville Intl - SAT San Antonio

SDFSAT

Louisville Intl

Sat 9/5

8:46 pm-9:15 am

1 stop13h 29m

San Antonio

Fri 9/11

10:05 am-10:11 am

2 stops23h 06m

$318

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Antonio from

How to get the cheapest flight ticket from Louisville to San Antonio

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Louisville and San Antonio?

Prices are currently low for flights on this route.

Typical prices usually range from $356 to $466.
The lowest price recently found on this route was $227.

What is the cheapest month to fly to San Antonio?

If you aren’t able to travel during the month of February, then book flights to San Antonio from Louisville during December instead. Flights to San Antonio in December, while not as cheap as those in February, still average around $367.

How far in advance should I book a flight from Louisville to San Antonio?

You are more likely to see cheaper flights to San Antonio from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Antonio for around $416 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Antonio from Louisville for as low as $335 on momondo.

How have Louisville to San Antonio flight prices changed over time?

As of August 2026, prices for Louisville to San Antonio flights are approximately 72% more expensive when compared to flights at the same time last year.

When to book flights from Louisville to San Antonio

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to San Antonio according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to San Antonio (SDF to SAT) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to San Antonio

Fastest flight time

4h 20m

Direct flights

None
The fastest flight from Louisville to San Antonio takes 4h 20m
There are no direct flights from Louisville to San Antonio. There are no popular flight routes from Louisville to San Antonio.
Search flight deals

Frequently asked questions about flying from Louisville to San Antonio

  • How far is Louisville Intl to San Antonio by plane?

    A flight from Louisville Intl to San Antonio will travel around 949.7 mi. 4h 20m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Louisville Intl Airport to San Antonio Airport?

    Prices for flights from Louisville Intl Airport to San Antonio Airport were last updated today.

  • How many operators does momondo search for flights from Louisville Intl Airport to San Antonio Airport?

  • How old do you have to be to fly from Louisville Intl Airport to San Antonio Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to San Antonio Airport.

  • What documentation or ID do you need to fly to San Antonio Airport?

    The required travel and health documents for your San Antonio Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Antonio Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Louisville to San Antonio?

Best airlines flying from Louisville to San Antonio

Compare and see reviews for airlines that fly from Louisville to San Antonio with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $127Free CancellationRating
7.8
8,502 reviews
Search Delta flights
American AirlinesPriceFrom $283Free CancellationRating
7.1
11,929 reviews
Search American Airlines flights
SouthwestPriceFrom $296Free CancellationRating
8.0
4,218 reviews
Search Southwest flights
United AirlinesPriceFrom $319Free CancellationRating
7.4
10,108 reviews
Search United Airlines flights

Traveling to a place near San Antonio?

Book flights to San Antonio if you plan to visit one of these locations
New Braunfels
Pleasanton
Kerrville
Boerne
Schertz

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to San Antonio?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Louisville to San Antonio for you.

Can I find flights from Louisville to San Antonio with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Antonio from Louisville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Louisville to San Antonio?

momondo helps you find the best flight between Louisville and San Antonio by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Louisville to San Antonio right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Louisville to San Antonio flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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