Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Knoxville to San Luis Obispo from $389

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to San Luis Obispo departing on 5/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to San Luis Obispo

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:36 am - 12:01 pm
TYS
-
SBP
9h 25m
1 stop
American Airlines Logo
12:52 pm - 11:55 pm
SBP
-
TYS
8h 03m
1 stop
$389American Airlines
Sat, May 30 - Fri, Jun 12
American Airlines Logo
6:00 am - 12:05 pm
TYS
-
SBP
9h 05m
1 stop
American Airlines Logo
12:55 pm - 11:56 pm
SBP
-
TYS
8h 01m
1 stop
$449American Airlines
Tue, May 12 - Sat, May 16
United Airlines Logo
4:20 pm - 9:16 pm
TYS
-
SBP
7h 56m
1 stop
United Airlines Logo
6:05 am - 10:23 pm
SBP
-
TYS
13h 18m
2 stops
$454United Airlines
Tue, May 12 - Sat, May 16
American Airlines Logo
5:00 am - 12:01 pm
TYS
-
SBP
10h 01m
2 stops
American Airlines Logo
12:52 pm - 11:55 pm
SBP
-
TYS
8h 03m
1 stop
$486American Airlines
Sat, May 30 - Fri, Jun 12
American Airlines Logo
6:00 am - 11:39 am
TYS
-
SBP
8h 39m
1 stop
American Airlines Logo
12:29 pm - 11:18 pm
SBP
-
TYS
7h 49m
1 stop
$503American Airlines
Thu, Aug 6 - Mon, Aug 10
United Airlines Logo
8:48 am - 5:24 pm
TYS
-
SBP
11h 36m
2 stops
United Airlines Logo
7:04 pm - 10:08 am
SBP
-
TYS
12h 04m
2 stops
$509United Airlines
Thu, Aug 6 - Mon, Aug 10
American Airlines Logo
5:36 am - 12:01 pm
TYS
-
SBP
9h 25m
1 stop
American Airlines Logo
12:52 pm - 11:55 pm
SBP
-
TYS
8h 03m
1 stop
$520American Airlines
Sat, May 30 - Mon, Jun 8
United Airlines Logo
4:56 pm - 8:50 pm
TYS
-
SBP
6h 54m
1 stop
United Airlines Logo
6:05 pm - 10:36 am
SBP
-
TYS
13h 31m
2 stops
$534United Airlines
Thu, Aug 6 - Mon, Aug 10
United Airlines Logo
9:50 am - 5:11 pm
TYS
-
SBP
10h 21m
2 stops
United Airlines Logo
7:16 am - 8:47 pm
SBP
-
TYS
10h 31m
2 stops
$539United Airlines
Tue, May 12 - Sat, May 16
American Airlines Logo
5:36 am - 12:01 pm
TYS
-
SBP
9h 25m
1 stop
American Airlines Logo
6:52 pm - 10:36 am
SBP
-
TYS
12h 44m
2 stops
$584American Airlines
Sat, May 30 - Mon, Jun 8

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

American Airlines flights from Knoxville to San Luis Obispo

Our best American Airlines deals on Knoxville to San Luis Obispo flight tickets
American Airlines
May 30
TYS5:36 amKnoxville McGhee Tyson
9h 25m
1 stop
SBP12:01 pmSan Luis Obispo County
Jun 12
SBP12:52 pmSan Luis Obispo County
8h 03m
1 stop
TYS11:55 pmKnoxville McGhee Tyson
$389
American Airlines
May 12
TYS6:00 amKnoxville McGhee Tyson
9h 05m
1 stop
SBP12:05 pmSan Luis Obispo County
May 16
SBP12:55 pmSan Luis Obispo County
8h 01m
1 stop
TYS11:56 pmKnoxville McGhee Tyson
$449
American Airlines
May 30
TYS5:00 amKnoxville McGhee Tyson
10h 01m
2 stops
SBP12:01 pmSan Luis Obispo County
Jun 12
SBP12:52 pmSan Luis Obispo County
8h 03m
1 stop
TYS11:55 pmKnoxville McGhee Tyson
$486

United Airlines flights from Knoxville to San Luis Obispo

Our best United Airlines deals on Knoxville to San Luis Obispo flight tickets
United Airlines
May 12
TYS4:20 pmKnoxville McGhee Tyson
7h 56m
1 stop
SBP9:16 pmSan Luis Obispo County
May 16
SBP6:05 amSan Luis Obispo County
13h 18m
2 stops
TYS10:23 pmKnoxville McGhee Tyson
$454
United Airlines
Aug 6
TYS8:48 amKnoxville McGhee Tyson
11h 36m
2 stops
SBP5:24 pmSan Luis Obispo County
Aug 10
SBP7:04 pmSan Luis Obispo County
12h 04m
2 stops
TYS10:08 amKnoxville McGhee Tyson
$509
United Airlines
Aug 6
TYS4:56 pmKnoxville McGhee Tyson
6h 54m
1 stop
SBP8:50 pmSan Luis Obispo County
Aug 10
SBP6:05 pmSan Luis Obispo County
13h 31m
2 stops
TYS10:36 amKnoxville McGhee Tyson
$534

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to San Luis Obispo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 29, 2026.
Use the filters below to find and compare flights from Knoxville to San Luis Obispo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Sat 5/30

5:36 am-12:01 pm

1 stop9h 25m

San Luis Obispo County

Fri 6/12

12:52 pm-11:55 pm

1 stop8h 03m

$389

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Tue 5/12

6:00 am-12:05 pm

1 stop9h 05m

San Luis Obispo County

Sat 5/16

12:55 pm-11:56 pm

1 stop8h 01m

$449

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Tue 5/12

4:20 pm-9:16 pm

1 stop7h 56m

San Luis Obispo County

Sat 5/16

6:05 am-10:23 pm

2 stops13h 18m

$454

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Sat 5/30

5:00 am-12:01 pm

2 stops10h 01m

San Luis Obispo County

Fri 6/12

12:52 pm-11:55 pm

1 stop8h 03m

$486
Quickest round-trip

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Thu 8/6

6:00 am-11:39 am

1 stop8h 39m

San Luis Obispo County

Mon 8/10

12:29 pm-11:18 pm

1 stop7h 49m

$503

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Thu 8/6

8:48 am-5:24 pm

2 stops11h 36m

San Luis Obispo County

Mon 8/10

7:04 pm-10:08 am

2 stops12h 04m

$509

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Sat 5/30

5:36 am-12:01 pm

1 stop9h 25m

San Luis Obispo County

Mon 6/8

12:52 pm-11:55 pm

1 stop8h 03m

$520

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Thu 8/6

4:56 pm-8:50 pm

1 stop6h 54m

San Luis Obispo County

Mon 8/10

6:05 pm-10:36 am

2 stops13h 31m

$534

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Tue 5/12

9:50 am-5:11 pm

2 stops10h 21m

San Luis Obispo County

Sat 5/16

7:16 am-8:47 pm

2 stops10h 31m

$539

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Sat 5/30

5:36 am-12:01 pm

1 stop9h 25m

San Luis Obispo County

Mon 6/8

6:52 pm-10:36 am

2 stops12h 44m

$584

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to San Luis Obispo from

How to get the cheapest flight ticket from Knoxville to San Luis Obispo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Knoxville and San Luis Obispo?

What is the cheapest month to fly to San Luis Obispo?

In general, November is the cheapest month to fly from Knoxville to San Luis Obispo. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $0. The month of September is another great option to travel to San Luis Obispo, with average flight prices from Knoxville averaging around $0.

When to book flights from Knoxville to San Luis Obispo

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to San Luis Obispo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to San Luis Obispo (TYS to SBP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to San Luis Obispo

Fastest flight time

6h 54m

Direct flights

None
The fastest flight from Knoxville to San Luis Obispo takes 6h 54m
There are no direct flights from Knoxville to San Luis Obispo. There are no popular flight routes from Knoxville to San Luis Obispo.
Search flight deals

Frequently asked questions about flying from Knoxville to San Luis Obispo

  • How far is Knoxville McGhee Tyson to San Luis Obispo County by plane?

    San Luis Obispo County is 2050.2 mi away from Knoxville McGhee Tyson. Flights usually cover this in 6h 54m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to San Luis Obispo County Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to San Luis Obispo County Airport are updated daily.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to San Luis Obispo County Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to San Luis Obispo County Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to San Luis Obispo County Airport.

  • What documentation or ID do you need to fly to San Luis Obispo County Airport?

    The required travel and health documents for your San Luis Obispo County Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Luis Obispo County Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Knoxville to San Luis Obispo?

Best airlines flying from Knoxville to San Luis Obispo

Compare and see reviews for airlines that fly from Knoxville to San Luis Obispo with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $308Free CancellationRating
7.1
11,678 reviews
Search American Airlines flights
United AirlinesPriceFrom $402Free CancellationRating
7.4
9,680 reviews
Search United Airlines flights

Traveling to a place near San Luis Obispo?

Book flights to San Luis Obispo if you plan to visit one of these locations
Pismo Beach
Paso Robles
Morro Bay
Cambria
Avila Beach
Cayucos
San Simeon
Arroyo Grande
Atascadero
Grover Beach

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to San Luis Obispo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Luis Obispo from Knoxville.

Can I find flights from Knoxville to San Luis Obispo with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Luis Obispo from Knoxville with this policy.

How can momondo help me find flights from Knoxville to San Luis Obispo?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to San Luis Obispo from Knoxville.

I’m not ready to book a flight from Knoxville to San Luis Obispo right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Knoxville to San Luis Obispo flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your San Luis Obispo trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Fri 5/29
Fri 6/5
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States