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Cheap flights from Knoxville to San Luis Obispo from $309

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to San Luis Obispo departing on 11/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Knoxville to San Luis Obispo

Cheap round-trip flights

American Airlines Logo
5:10 am - 11:43 amTYS-SBP
9h 33m1 stop
American Airlines Logo
12:28 pm - 12:16 amSBP-TYS
8h 48m1 stop
$309American Airlines
Find Deal
Fri, Nov 7 - Tue, Nov 11
American Airlines Logo
7:05 am - 11:36 amTYS-SBP
7h 31m1 stop
American Airlines Logo
7:11 pm - 8:34 amSBP-TYS
10h 23m2 stops
$314American Airlines
Find Deal
Sat, Oct 25 - Sat, Nov 22
American Airlines Logo
7:00 am - 4:06 pmTYS-SBP
12h 06m2 stops
American Airlines Logo
7:11 pm - 8:34 amSBP-TYS
10h 23m2 stops
$319American Airlines
Find Deal
Sat, Oct 25 - Sat, Nov 22
American Airlines Logo
5:10 am - 11:43 amTYS-SBP
9h 33m1 stop
American Airlines Logo
12:28 pm - 12:16 amSBP-TYS
8h 48m1 stop
$339American Airlines
Find Deal
Fri, Nov 7 - Mon, Nov 10
American Airlines Logo
5:10 am - 12:12 pmTYS-SBP
10h 02m2 stops
American Airlines Logo
9:53 am - 11:45 pmSBP-TYS
10h 52m2 stops
$349American Airlines
Find Deal
Fri, Nov 7 - Tue, Nov 11
American Airlines Logo
5:10 am - 12:12 pmTYS-SBP
10h 02m2 stops
American Airlines Logo
12:28 pm - 12:16 amSBP-TYS
8h 48m1 stop
$374American Airlines
Find Deal
Fri, Nov 7 - Mon, Nov 10
United Airlines Logo
4:55 pm - 9:08 pmTYS-SBP
7h 13m1 stop
United Airlines Logo
6:25 pm - 10:05 amSBP-TYS
12h 40m2 stops
$414United Airlines
Find Deal
Thu, Oct 30 - Mon, Nov 3
United Airlines Logo
10:50 am - 9:34 pmTYS-SBP
13h 44m2 stops
United Airlines Logo
6:25 pm - 10:05 amSBP-TYS
12h 40m2 stops
$419United Airlines
Find Deal
Thu, Oct 30 - Mon, Nov 3
United Airlines Logo
2:00 pm - 11:43 pmTYS-SBP
12h 43m2 stops
United Airlines Logo
6:22 pm - 10:10 amSBP-TYS
12h 48m2 stops
$490United Airlines
Find Deal
Sat, Oct 4 - Mon, Oct 6
Alaska Airlines Logo
5:30 am - 6:58 pmTYS-SBP
16h 28m2 stops
Alaska Airlines Logo
7:50 pm - 11:44 amSBP-TYS
12h 54m2 stops
$597Alaska Airlines
Find Deal
Sun, Oct 5 - Wed, Oct 15

American Airlines flights from Knoxville to San Luis Obispo

Our best American Airlines deals on Knoxville to San Luis Obispo flight tickets
American Airlines
Nov 7
TYS5:10 amKnoxville McGhee Tyson
9h 33m
1 stop
SBP11:43 amSan Luis Obispo County
Nov 11
SBP12:28 pmSan Luis Obispo County
8h 48m
1 stop
TYS12:16 amKnoxville McGhee Tyson
$309
Find similar
American Airlines
Oct 25
TYS7:05 amKnoxville McGhee Tyson
7h 31m
1 stop
SBP11:36 amSan Luis Obispo County
Nov 22
SBP7:11 pmSan Luis Obispo County
10h 23m
2 stops
TYS8:34 amKnoxville McGhee Tyson
$314
Find similar
American Airlines
Oct 25
TYS7:00 amKnoxville McGhee Tyson
12h 06m
2 stops
SBP4:06 pmSan Luis Obispo County
Nov 22
SBP7:11 pmSan Luis Obispo County
10h 23m
2 stops
TYS8:34 amKnoxville McGhee Tyson
$319
Find similar

United Airlines flights from Knoxville to San Luis Obispo

Our best United Airlines deals on Knoxville to San Luis Obispo flight tickets
United Airlines
Oct 30
TYS4:55 pmKnoxville McGhee Tyson
7h 13m
1 stop
SBP9:08 pmSan Luis Obispo County
Nov 3
SBP6:25 pmSan Luis Obispo County
12h 40m
2 stops
TYS10:05 amKnoxville McGhee Tyson
$414
Find similar
United Airlines
Oct 30
TYS10:50 amKnoxville McGhee Tyson
13h 44m
2 stops
SBP9:34 pmSan Luis Obispo County
Nov 3
SBP6:25 pmSan Luis Obispo County
12h 40m
2 stops
TYS10:05 amKnoxville McGhee Tyson
$419
Find similar
United Airlines
Oct 4
TYS2:00 pmKnoxville McGhee Tyson
12h 43m
2 stops
SBP11:43 pmSan Luis Obispo County
Oct 6
SBP6:22 pmSan Luis Obispo County
12h 48m
2 stops
TYS10:10 amKnoxville McGhee Tyson
$490
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to San Luis Obispo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Knoxville to San Luis Obispo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Fri 11/7

5:10 am-11:43 am

1 stop9h 33m

San Luis Obispo County

Tue 11/11

12:28 pm-12:16 am

1 stop8h 48m

$309

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Sat 10/25

7:05 am-11:36 am

1 stop7h 31m

San Luis Obispo County

Sat 11/22

7:11 pm-8:34 am

2 stops10h 23m

$314

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Sat 10/25

7:00 am-4:06 pm

2 stops12h 06m

San Luis Obispo County

Sat 11/22

7:11 pm-8:34 am

2 stops10h 23m

$319

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Fri 11/7

5:10 am-11:43 am

1 stop9h 33m

San Luis Obispo County

Mon 11/10

12:28 pm-12:16 am

1 stop8h 48m

$339

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Fri 11/7

5:10 am-12:12 pm

2 stops10h 02m

San Luis Obispo County

Tue 11/11

9:53 am-11:45 pm

2 stops10h 52m

$349

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Fri 11/7

5:10 am-12:12 pm

2 stops10h 02m

San Luis Obispo County

Mon 11/10

12:28 pm-12:16 am

1 stop8h 48m

$374

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Thu 10/30

4:55 pm-9:08 pm

1 stop7h 13m

San Luis Obispo County

Mon 11/3

6:25 pm-10:05 am

2 stops12h 40m

$414

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Thu 10/30

10:50 am-9:34 pm

2 stops13h 44m

San Luis Obispo County

Mon 11/3

6:25 pm-10:05 am

2 stops12h 40m

$419

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Sat 10/4

2:00 pm-11:43 pm

2 stops12h 43m

San Luis Obispo County

Mon 10/6

6:22 pm-10:10 am

2 stops12h 48m

$490

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Sun 10/5

5:30 am-6:58 pm

2 stops16h 28m

San Luis Obispo County

Wed 10/15

7:50 pm-11:44 am

2 stops12h 54m

$597

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Luis Obispo from

How to get the cheapest flight ticket from Knoxville to San Luis Obispo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to San Luis Obispo?

On average, the least expensive day to fly to San Luis Obispo from Knoxville is on a Saturday. momondo users have found tickets for Saturday departures for as low as $308. However, this price may fluctuate depending on the airline, the season, and holidays. When flying out on a Thursday, the most expensive travel day of the week, you can expect to see flight prices from Knoxville to San Luis Obispo for around $658.

What is the cheapest time of day to depart on your flight to San Luis Obispo?

Flying to San Luis Obispo from Knoxville in the morning is the least expensive time of day to depart. momondo users have found prices as low as $474 when looking at flights departing in the morning. If you have a flexible travel schedule, then try to avoid flying in the afternoon when prices are $628 on average. Flights to San Luis Obispo from Knoxville in the afternoon are generally more expensive because this time of day is more convenient for travelers’ schedules.

When to book flights from Knoxville to San Luis Obispo

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to San Luis Obispo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to San Luis Obispo (TYS to SBP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to San Luis Obispo

Best Price Found

$312

Fastest flight time

7h 04m

Direct flights

None

Airports in San Luis Obispo

1 airport
The best one-way flight to San Luis Obispo from Knoxville in the past 72 hours is $312. The best round-trip flight deal from Knoxville to San Luis Obispo found on momondo in the last 72 hours is $309.
The fastest flight from Knoxville to San Luis Obispo takes 7h 04m
There are no direct flights from Knoxville to San Luis Obispo. Popular non-direct route for this connection is Knoxville McGhee Tyson Airport - San Luis Obispo County Airport.
There is 1 airport near San Luis Obispo: San Luis Obispo County (SBP)
Search flight deals

  • How far is Knoxville McGhee Tyson to San Luis Obispo County by plane?

    San Luis Obispo County is 2050.2 mi away from Knoxville McGhee Tyson. Flights usually cover this in 7h 13m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to San Luis Obispo County Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to San Luis Obispo County Airport are updated daily.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to San Luis Obispo County Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to San Luis Obispo County Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to San Luis Obispo County Airport.

  • What documentation or ID do you need to fly to San Luis Obispo County Airport?

    The required travel and health documents for your San Luis Obispo County Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Luis Obispo County Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Knoxville to San Luis Obispo?

Best airlines flying from Knoxville to San Luis Obispo

Compare and see reviews for airlines that fly from Knoxville to San Luis Obispo with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $308Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near San Luis Obispo?

Book flights to San Luis Obispo if you plan to visit one of these locations
Pismo Beach
Morro Bay
Cambria
Paso Robles
Avila Beach
San Simeon
Cayucos
Atascadero
Arroyo Grande
Grover Beach

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to San Luis Obispo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Luis Obispo from Knoxville.

Can I find flights from Knoxville to San Luis Obispo with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Luis Obispo from Knoxville with this policy.

How can momondo help me find flights from Knoxville to San Luis Obispo?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to San Luis Obispo from Knoxville.

I’m not ready to book a flight from Knoxville to San Luis Obispo right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Knoxville to San Luis Obispo flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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