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Cheap flights from Knoxville to San Luis Obispo from $505

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to San Luis Obispo departing on 5/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Knoxville to San Luis Obispo

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
4:56 pm - 11:44 pm
TYS
-
SBP
9h 48m
2 stops
United Airlines Logo
5:00 am - 3:53 pm
SBP
-
TYS
7h 53m
1 stop
$505United Airlines
Thu, May 28 - Mon, Jun 8
United Airlines Logo
4:56 pm - 11:44 pm
TYS
-
SBP
9h 48m
2 stops
United Airlines Logo
6:05 pm - 10:05 am
SBP
-
TYS
13h 00m
2 stops
$510United Airlines
Thu, May 28 - Mon, Jun 8
United Airlines Logo
4:56 pm - 8:50 pm
TYS
-
SBP
6h 54m
1 stop
United Airlines Logo
5:00 am - 3:53 pm
SBP
-
TYS
7h 53m
1 stop
$520United Airlines
Fri, May 29 - Mon, Jun 8
United Airlines Logo
8:48 am - 11:44 pm
TYS
-
SBP
17h 56m
2 stops
United Airlines Logo
7:04 pm - 10:08 am
SBP
-
TYS
12h 04m
2 stops
$523United Airlines
Thu, Aug 6 - Mon, Aug 10
United Airlines Logo
4:18 pm - 11:44 pm
TYS
-
SBP
10h 26m
2 stops
United Airlines Logo
6:00 pm - 10:19 am
SBP
-
TYS
13h 19m
2 stops
$540United Airlines
Thu, Mar 12 - Mon, Mar 16
American Airlines Logo
5:05 am - 12:05 pm
TYS
-
SBP
10h 00m
1 stop
American Airlines Logo
12:45 pm - 11:51 pm
SBP
-
TYS
8h 06m
1 stop
$544American Airlines
Tue, Mar 24 - Sun, Mar 29
American Airlines Logo
5:05 am - 12:05 pm
TYS
-
SBP
10h 00m
1 stop
American Airlines Logo
12:45 pm - 11:51 pm
SBP
-
TYS
8h 06m
1 stop
$548American Airlines
Tue, Mar 24 - Sun, Mar 29
United Airlines Logo
4:56 pm - 8:50 pm
TYS
-
SBP
6h 54m
1 stop
United Airlines Logo
5:00 am - 3:53 pm
SBP
-
TYS
7h 53m
1 stop
$552United Airlines
Thu, May 28 - Mon, Jun 8
United Airlines Logo
8:48 am - 1:09 pm
TYS
-
SBP
7h 21m
1 stop
United Airlines Logo
5:00 am - 3:53 pm
SBP
-
TYS
7h 53m
1 stop
$562United Airlines
Thu, Aug 6 - Mon, Aug 10
United Airlines Logo
4:18 pm - 9:04 pm
TYS
-
SBP
7h 46m
1 stop
United Airlines Logo
6:00 pm - 10:19 am
SBP
-
TYS
13h 19m
2 stops
$584United Airlines
Thu, Mar 12 - Mon, Mar 16

United Airlines flights from Knoxville to San Luis Obispo

Our best United Airlines deals on Knoxville to San Luis Obispo flight tickets
United Airlines
May 28
TYS4:56 pmKnoxville McGhee Tyson
9h 48m
2 stops
SBP11:44 pmSan Luis Obispo County
Jun 8
SBP5:00 amSan Luis Obispo County
7h 53m
1 stop
TYS3:53 pmKnoxville McGhee Tyson
$505
United Airlines
May 28
TYS4:56 pmKnoxville McGhee Tyson
9h 48m
2 stops
SBP11:44 pmSan Luis Obispo County
Jun 8
SBP6:05 pmSan Luis Obispo County
13h 00m
2 stops
TYS10:05 amKnoxville McGhee Tyson
$510
United Airlines
May 29
TYS4:56 pmKnoxville McGhee Tyson
6h 54m
1 stop
SBP8:50 pmSan Luis Obispo County
Jun 8
SBP5:00 amSan Luis Obispo County
7h 53m
1 stop
TYS3:53 pmKnoxville McGhee Tyson
$520

American Airlines flights from Knoxville to San Luis Obispo

Our best American Airlines deals on Knoxville to San Luis Obispo flight tickets
American Airlines
Mar 24
TYS5:05 amKnoxville McGhee Tyson
10h 00m
1 stop
SBP12:05 pmSan Luis Obispo County
Mar 29
SBP12:45 pmSan Luis Obispo County
8h 06m
1 stop
TYS11:51 pmKnoxville McGhee Tyson
$544
American Airlines
Mar 24
TYS5:05 amKnoxville McGhee Tyson
10h 00m
1 stop
SBP12:05 pmSan Luis Obispo County
Mar 29
SBP12:45 pmSan Luis Obispo County
8h 06m
1 stop
TYS11:51 pmKnoxville McGhee Tyson
$548
American Airlines
Mar 24
TYS5:05 amKnoxville McGhee Tyson
10h 00m
1 stop
SBP12:05 pmSan Luis Obispo County
Mar 29
SBP7:10 pmSan Luis Obispo County
10h 32m
2 stops
TYS8:42 amKnoxville McGhee Tyson
$586

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to San Luis Obispo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 1, 2026.
Use the filters below to find and compare flights from Knoxville to San Luis Obispo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Thu 5/28

4:56 pm-11:44 pm

2 stops9h 48m

San Luis Obispo County

Mon 6/8

5:00 am-3:53 pm

1 stop7h 53m

$505

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Thu 5/28

4:56 pm-11:44 pm

2 stops9h 48m

San Luis Obispo County

Mon 6/8

6:05 pm-10:05 am

2 stops13h 00m

$510

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Fri 5/29

4:56 pm-8:50 pm

1 stop6h 54m

San Luis Obispo County

Mon 6/8

5:00 am-3:53 pm

1 stop7h 53m

$520

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Thu 8/6

8:48 am-11:44 pm

2 stops17h 56m

San Luis Obispo County

Mon 8/10

7:04 pm-10:08 am

2 stops12h 04m

$523

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Thu 3/12

4:18 pm-11:44 pm

2 stops10h 26m

San Luis Obispo County

Mon 3/16

6:00 pm-10:19 am

2 stops13h 19m

$540

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Tue 3/24

5:05 am-12:05 pm

1 stop10h 00m

San Luis Obispo County

Sun 3/29

12:45 pm-11:51 pm

1 stop8h 06m

$544

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Tue 3/24

5:05 am-12:05 pm

1 stop10h 00m

San Luis Obispo County

Sun 3/29

12:45 pm-11:51 pm

1 stop8h 06m

$548

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Thu 5/28

4:56 pm-8:50 pm

1 stop6h 54m

San Luis Obispo County

Mon 6/8

5:00 am-3:53 pm

1 stop7h 53m

$552

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Thu 8/6

8:48 am-1:09 pm

1 stop7h 21m

San Luis Obispo County

Mon 8/10

5:00 am-3:53 pm

1 stop7h 53m

$562

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Thu 3/12

4:18 pm-9:04 pm

1 stop7h 46m

San Luis Obispo County

Mon 3/16

6:00 pm-10:19 am

2 stops13h 19m

$584

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
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See travel insights to San Luis Obispo from

How to get the cheapest flight ticket from Knoxville to San Luis Obispo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Knoxville McGhee Tyson to San Luis Obispo County?

United Airlines and American Airlines are the most popular carriers operating from Knoxville McGhee Tyson to San Luis Obispo County

What airlines fly to San Luis Obispo?

American Airlines, United Airlines and Delta are the top three most popular airlines that fly to San Luis Obispo from Knoxville according to our data. American Airlines is the first choice among our users, with 74% of people opting to fly with this airline when traveling to San Luis Obispo. Keep in mind that there are 3 different airlines that fly to San Luis Obispo on a routine basis, so you have a few additional options to choose from.

When to book flights from Knoxville to San Luis Obispo

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to San Luis Obispo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to San Luis Obispo (TYS to SBP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to San Luis Obispo

Fastest flight time

7h 46m

Direct flights

None
The fastest flight from Knoxville to San Luis Obispo takes 7h 46m
There are no direct flights from Knoxville to San Luis Obispo. There are no popular flight routes from Knoxville to San Luis Obispo.
Search flight deals

  • How far is Knoxville McGhee Tyson to San Luis Obispo County by plane?

    San Luis Obispo County is 2050.2 mi away from Knoxville McGhee Tyson. Flights usually cover this in 7h 46m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to San Luis Obispo County Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to San Luis Obispo County Airport are updated daily.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to San Luis Obispo County Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to San Luis Obispo County Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to San Luis Obispo County Airport.

  • What documentation or ID do you need to fly to San Luis Obispo County Airport?

    The required travel and health documents for your San Luis Obispo County Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Luis Obispo County Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Knoxville to San Luis Obispo?

Best airlines flying from Knoxville to San Luis Obispo

Compare and see reviews for airlines that fly from Knoxville to San Luis Obispo with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $308Free CancellationRating
7.1
11,370 reviews
Search American Airlines flights

Traveling to a place near San Luis Obispo?

Book flights to San Luis Obispo if you plan to visit one of these locations
Pismo Beach
Morro Bay
Paso Robles
Cambria
Avila Beach
San Simeon
Cayucos
Arroyo Grande
Atascadero
Grover Beach

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to San Luis Obispo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Luis Obispo from Knoxville.

Can I find flights from Knoxville to San Luis Obispo with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Luis Obispo from Knoxville with this policy.

How can momondo help me find flights from Knoxville to San Luis Obispo?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to San Luis Obispo from Knoxville.

I’m not ready to book a flight from Knoxville to San Luis Obispo right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Knoxville to San Luis Obispo flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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