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Cheap flights from Knoxville to San Luis Obispo from $309

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to San Luis Obispo departing on 10/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Knoxville to San Luis Obispo

Cheap round-trip flights

American Airlines Logo
6:00 am - 11:37 amTYS-SBP
8h 37m1 stop
American Airlines Logo
12:28 pm - 11:59 pmSBP-TYS
8h 31m1 stop
$309American Airlines
Find Deal
Sat, Oct 25 - Sat, Dec 6
American Airlines Logo
6:00 am - 11:37 amTYS-SBP
8h 37m1 stop
American Airlines Logo
9:55 am - 11:57 pmSBP-TYS
11h 02m2 stops
$314American Airlines
Find Deal
Sat, Oct 25 - Sat, Dec 6
American Airlines Logo
6:00 am - 11:57 amTYS-SBP
8h 57m2 stops
American Airlines Logo
9:55 am - 11:57 pmSBP-TYS
11h 02m2 stops
$319American Airlines
Find Deal
Sat, Oct 25 - Sat, Dec 6
American Airlines Logo
5:10 am - 11:43 amTYS-SBP
9h 33m1 stop
American Airlines Logo
12:28 pm - 12:08 amSBP-TYS
8h 40m1 stop
$339American Airlines
Find Deal
Fri, Nov 7 - Tue, Nov 11
American Airlines Logo
6:00 am - 11:37 amTYS-SBP
8h 37m1 stop
American Airlines Logo
12:57 pm - 12:08 amSBP-TYS
8h 11m2 stops
$344American Airlines
Find Deal
Thu, Oct 30 - Mon, Nov 3
American Airlines Logo
5:00 am - 11:37 amTYS-SBP
9h 37m2 stops
American Airlines Logo
12:57 pm - 12:08 amSBP-TYS
8h 11m2 stops
$379American Airlines
Find Deal
Thu, Oct 30 - Mon, Nov 3
American Airlines Logo
5:10 am - 11:43 amTYS-SBP
9h 33m1 stop
American Airlines Logo
12:28 pm - 11:59 pmSBP-TYS
8h 31m1 stop
$380American Airlines
Find Deal
Wed, Nov 26 - Wed, Dec 3
American Airlines Logo
5:10 am - 11:43 amTYS-SBP
9h 33m1 stop
American Airlines Logo
1:03 pm - 11:59 pmSBP-TYS
7h 56m2 stops
$385American Airlines
Find Deal
Wed, Nov 26 - Wed, Dec 3
United Airlines Logo
4:40 pm - 8:52 pmTYS-SBP
7h 12m1 stop
United Airlines Logo
6:07 pm - 10:05 amSBP-TYS
12h 58m2 stops
$444United Airlines
Find Deal
Sat, Oct 25 - Sat, Nov 22
United Airlines Logo
1:52 pm - 9:34 pmTYS-SBP
10h 42m2 stops
United Airlines Logo
5:02 am - 7:29 pmSBP-TYS
11h 27m2 stops
$464United Airlines
Find Deal
Wed, Nov 26 - Wed, Dec 3

American Airlines flights from Knoxville to San Luis Obispo

Our best American Airlines deals on Knoxville to San Luis Obispo flight tickets
American Airlines
Oct 25
TYS6:00 amKnoxville McGhee Tyson
8h 37m
1 stop
SBP11:37 amSan Luis Obispo County
Dec 6
SBP12:28 pmSan Luis Obispo County
8h 31m
1 stop
TYS11:59 pmKnoxville McGhee Tyson
$309
Find similar
American Airlines
Oct 25
TYS6:00 amKnoxville McGhee Tyson
8h 37m
1 stop
SBP11:37 amSan Luis Obispo County
Dec 6
SBP9:55 amSan Luis Obispo County
11h 02m
2 stops
TYS11:57 pmKnoxville McGhee Tyson
$314
Find similar
American Airlines
Oct 25
TYS6:00 amKnoxville McGhee Tyson
8h 57m
2 stops
SBP11:57 amSan Luis Obispo County
Dec 6
SBP9:55 amSan Luis Obispo County
11h 02m
2 stops
TYS11:57 pmKnoxville McGhee Tyson
$319
Find similar

United Airlines flights from Knoxville to San Luis Obispo

Our best United Airlines deals on Knoxville to San Luis Obispo flight tickets
United Airlines
Oct 25
TYS4:40 pmKnoxville McGhee Tyson
7h 12m
1 stop
SBP8:52 pmSan Luis Obispo County
Nov 22
SBP6:07 pmSan Luis Obispo County
12h 58m
2 stops
TYS10:05 amKnoxville McGhee Tyson
$444
Find similar
United Airlines
Nov 26
TYS1:52 pmKnoxville McGhee Tyson
10h 42m
2 stops
SBP9:34 pmSan Luis Obispo County
Dec 3
SBP5:02 amSan Luis Obispo County
11h 27m
2 stops
TYS7:29 pmKnoxville McGhee Tyson
$464
Find similar
United Airlines
Oct 17
TYS4:40 pmKnoxville McGhee Tyson
7h 12m
1 stop
SBP8:52 pmSan Luis Obispo County
Oct 18
SBP8:00 amSan Luis Obispo County
11h 50m
2 stops
TYS10:50 pmKnoxville McGhee Tyson
$529
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to San Luis Obispo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Knoxville to San Luis Obispo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Sat 10/25

6:00 am-11:37 am

1 stop8h 37m

San Luis Obispo County

Sat 12/6

12:28 pm-11:59 pm

1 stop8h 31m

$309

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Sat 10/25

6:00 am-11:37 am

1 stop8h 37m

San Luis Obispo County

Sat 12/6

9:55 am-11:57 pm

2 stops11h 02m

$314

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Sat 10/25

6:00 am-11:57 am

2 stops8h 57m

San Luis Obispo County

Sat 12/6

9:55 am-11:57 pm

2 stops11h 02m

$319

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Fri 11/7

5:10 am-11:43 am

1 stop9h 33m

San Luis Obispo County

Tue 11/11

12:28 pm-12:08 am

1 stop8h 40m

$339

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Thu 10/30

6:00 am-11:37 am

1 stop8h 37m

San Luis Obispo County

Mon 11/3

12:57 pm-12:08 am

2 stops8h 11m

$344

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Thu 10/30

5:00 am-11:37 am

2 stops9h 37m

San Luis Obispo County

Mon 11/3

12:57 pm-12:08 am

2 stops8h 11m

$379

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Wed 11/26

5:10 am-11:43 am

1 stop9h 33m

San Luis Obispo County

Wed 12/3

12:28 pm-11:59 pm

1 stop8h 31m

$380

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Wed 11/26

5:10 am-11:43 am

1 stop9h 33m

San Luis Obispo County

Wed 12/3

1:03 pm-11:59 pm

2 stops7h 56m

$385

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Sat 10/25

4:40 pm-8:52 pm

1 stop7h 12m

San Luis Obispo County

Sat 11/22

6:07 pm-10:05 am

2 stops12h 58m

$444

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Wed 11/26

1:52 pm-9:34 pm

2 stops10h 42m

San Luis Obispo County

Wed 12/3

5:02 am-7:29 pm

2 stops11h 27m

$464

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to San Luis Obispo from

How to get the cheapest flight ticket from Knoxville to San Luis Obispo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to San Luis Obispo?

On average, the least expensive day to fly to San Luis Obispo from Knoxville is on a Saturday. momondo users have found tickets for Saturday departures for as low as $308. However, this price may fluctuate depending on the airline, the season, and holidays. When flying out on a Thursday, the most expensive travel day of the week, you can expect to see flight prices from Knoxville to San Luis Obispo for around $658.

What is the cheapest time of day to depart on your flight to San Luis Obispo?

Flying to San Luis Obispo from Knoxville in the morning is the least expensive time of day to depart. momondo users have found prices as low as $474 when looking at flights departing in the morning. If you have a flexible travel schedule, then try to avoid flying in the afternoon when prices are $628 on average. Flights to San Luis Obispo from Knoxville in the afternoon are generally more expensive because this time of day is more convenient for travelers’ schedules.

When to book flights from Knoxville to San Luis Obispo

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to San Luis Obispo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to San Luis Obispo (TYS to SBP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to San Luis Obispo

Direct flights

None
There are no direct flights from Knoxville to San Luis Obispo. There are no popular flight routes from Knoxville to San Luis Obispo.
Search flight deals

  • How far is Knoxville McGhee Tyson to San Luis Obispo County by plane?

    San Luis Obispo County is 2050.2 mi away from Knoxville McGhee Tyson. Flights usually cover this in 7h 06m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to San Luis Obispo County Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to San Luis Obispo County Airport are updated daily.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to San Luis Obispo County Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to San Luis Obispo County Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to San Luis Obispo County Airport.

  • What documentation or ID do you need to fly to San Luis Obispo County Airport?

    The required travel and health documents for your San Luis Obispo County Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Luis Obispo County Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Knoxville to San Luis Obispo?

Best airlines flying from Knoxville to San Luis Obispo

Compare and see reviews for airlines that fly from Knoxville to San Luis Obispo with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $308Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near San Luis Obispo?

Book flights to San Luis Obispo if you plan to visit one of these locations
Pismo Beach
Morro Bay
Cambria
Paso Robles
Avila Beach
San Simeon
Cayucos
Arroyo Grande
Atascadero
Grover Beach

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to San Luis Obispo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Luis Obispo from Knoxville.

Can I find flights from Knoxville to San Luis Obispo with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Luis Obispo from Knoxville with this policy.

How can momondo help me find flights from Knoxville to San Luis Obispo?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to San Luis Obispo from Knoxville.

I’m not ready to book a flight from Knoxville to San Luis Obispo right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Knoxville to San Luis Obispo flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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