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Cheap flights from Knoxville to San Luis Obispo from $369

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to San Luis Obispo departing on 8/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to San Luis Obispo

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:03 am - 11:39 am
TYS
-
SBP
8h 36m
1 stop
American Airlines Logo
12:29 pm - 11:18 pm
SBP
-
TYS
7h 49m
1 stop
$369American Airlines
Thu, Aug 6 - Mon, Aug 10
American Airlines Logo
5:37 am - 11:43 am
TYS
-
SBP
9h 06m
1 stop
American Airlines Logo
7:02 pm - 9:43 am
SBP
-
TYS
11h 41m
2 stops
$374American Airlines
Thu, Jul 30 - Tue, Aug 4
American Airlines Logo
5:10 am - 12:12 pm
TYS
-
SBP
10h 02m
2 stops
American Airlines Logo
9:53 am - 11:52 pm
SBP
-
TYS
10h 59m
2 stops
$449American Airlines
Wed, Nov 4 - Sat, Nov 7
American Airlines Logo
5:15 am - 11:58 am
TYS
-
SBP
9h 43m
2 stops
American Airlines Logo
12:29 pm - 11:18 pm
SBP
-
TYS
7h 49m
1 stop
$451American Airlines
Thu, Aug 6 - Mon, Aug 10
American Airlines Logo
7:30 am - 11:45 am
TYS
-
SBP
7h 15m
1 stop
American Airlines Logo
12:34 pm - 11:18 pm
SBP
-
TYS
7h 44m
1 stop
$459American Airlines
Fri, Oct 23 - Tue, Oct 27
American Airlines Logo
6:00 am - 11:45 am
TYS
-
SBP
8h 45m
1 stop
American Airlines Logo
7:34 pm - 8:22 am
SBP
-
TYS
9h 48m
2 stops
$464American Airlines
Fri, Oct 23 - Tue, Oct 27
American Airlines Logo
2:17 pm - 10:02 pm
TYS
-
SBP
10h 45m
2 stops
American Airlines Logo
7:34 pm - 8:22 am
SBP
-
TYS
9h 48m
2 stops
$470American Airlines
Fri, Oct 23 - Tue, Oct 27
United Airlines Logo
4:25 pm - 9:24 pm
TYS
-
SBP
7h 59m
1 stop
United Airlines Logo
5:40 pm - 10:00 am
SBP
-
TYS
13h 20m
2 stops
$484United Airlines
Sat, Oct 31 - Tue, Nov 3
United Airlines Logo
7:00 am - 5:19 pm
TYS
-
SBP
13h 19m
2 stops
United Airlines Logo
5:40 pm - 10:00 am
SBP
-
TYS
13h 20m
2 stops
$489United Airlines
Sat, Oct 31 - Tue, Nov 3
American Airlines Logo
1:54 pm - 10:50 pm
TYS
-
SBP
11h 56m
2 stops
American Airlines Logo
7:02 pm - 10:38 am
SBP
-
TYS
12h 36m
2 stops
$500American Airlines
Fri, Jul 17 - Mon, Jul 20

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American Airlines flights from Knoxville to San Luis Obispo

Our best American Airlines deals on Knoxville to San Luis Obispo flight tickets
American Airlines
Aug 6
TYS6:03 amKnoxville McGhee Tyson
8h 36m
1 stop
SBP11:39 amSan Luis Obispo County
Aug 10
SBP12:29 pmSan Luis Obispo County
7h 49m
1 stop
TYS11:18 pmKnoxville McGhee Tyson
$369
American Airlines
Jul 30
TYS5:37 amKnoxville McGhee Tyson
9h 06m
1 stop
SBP11:43 amSan Luis Obispo County
Aug 4
SBP7:02 pmSan Luis Obispo County
11h 41m
2 stops
TYS9:43 amKnoxville McGhee Tyson
$374
American Airlines
Nov 4
TYS5:10 amKnoxville McGhee Tyson
10h 02m
2 stops
SBP12:12 pmSan Luis Obispo County
Nov 7
SBP9:53 amSan Luis Obispo County
10h 59m
2 stops
TYS11:52 pmKnoxville McGhee Tyson
$449

United Airlines flights from Knoxville to San Luis Obispo

Our best United Airlines deals on Knoxville to San Luis Obispo flight tickets
United Airlines
Oct 31
TYS4:25 pmKnoxville McGhee Tyson
7h 59m
1 stop
SBP9:24 pmSan Luis Obispo County
Nov 3
SBP5:40 pmSan Luis Obispo County
13h 20m
2 stops
TYS10:00 amKnoxville McGhee Tyson
$484
United Airlines
Oct 31
TYS8:45 amKnoxville McGhee Tyson
12h 11m
2 stops
SBP5:56 pmSan Luis Obispo County
Nov 3
SBP5:40 pmSan Luis Obispo County
13h 20m
2 stops
TYS10:00 amKnoxville McGhee Tyson
$489
United Airlines
Aug 6
TYS8:48 amKnoxville McGhee Tyson
11h 36m
2 stops
SBP5:24 pmSan Luis Obispo County
Aug 10
SBP8:28 pmSan Luis Obispo County
10h 29m
2 stops
TYS9:57 amKnoxville McGhee Tyson
$566

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to San Luis Obispo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 15, 2026.
Use the filters below to find and compare flights from Knoxville to San Luis Obispo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Thu 8/6

6:03 am-11:39 am

1 stop8h 36m

San Luis Obispo County

Mon 8/10

12:29 pm-11:18 pm

1 stop7h 49m

$369

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Thu 7/30

5:37 am-11:43 am

1 stop9h 06m

San Luis Obispo County

Tue 8/4

7:02 pm-9:43 am

2 stops11h 41m

$374

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Wed 11/4

5:10 am-12:12 pm

2 stops10h 02m

San Luis Obispo County

Sat 11/7

9:53 am-11:52 pm

2 stops10h 59m

$449

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Thu 8/6

5:15 am-11:58 am

2 stops9h 43m

San Luis Obispo County

Mon 8/10

12:29 pm-11:18 pm

1 stop7h 49m

$451
Quickest round-trip

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Fri 10/23

7:30 am-11:45 am

1 stop7h 15m

San Luis Obispo County

Tue 10/27

12:34 pm-11:18 pm

1 stop7h 44m

$459

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Fri 10/23

6:00 am-11:45 am

1 stop8h 45m

San Luis Obispo County

Tue 10/27

7:34 pm-8:22 am

2 stops9h 48m

$464

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Fri 10/23

2:17 pm-10:02 pm

2 stops10h 45m

San Luis Obispo County

Tue 10/27

7:34 pm-8:22 am

2 stops9h 48m

$470

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Sat 10/31

4:25 pm-9:24 pm

1 stop7h 59m

San Luis Obispo County

Tue 11/3

5:40 pm-10:00 am

2 stops13h 20m

$484

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Sat 10/31

7:00 am-5:19 pm

2 stops13h 19m

San Luis Obispo County

Tue 11/3

5:40 pm-10:00 am

2 stops13h 20m

$489

KnoxvilleSan Luis Obispo

TYS - SBP

TYSSBP

Knoxville McGhee Tyson

Fri 7/17

1:54 pm-10:50 pm

2 stops11h 56m

San Luis Obispo County

Mon 7/20

7:02 pm-10:38 am

2 stops12h 36m

$500

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to San Luis Obispo from

How to get the cheapest flight ticket from Knoxville to San Luis Obispo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Knoxville and San Luis Obispo?

What is the cheapest month to fly to San Luis Obispo?

In general, November is the cheapest month to fly from Knoxville to San Luis Obispo. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $0. The month of September is another great option to travel to San Luis Obispo, with average flight prices from Knoxville averaging around $0.

When to book flights from Knoxville to San Luis Obispo

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to San Luis Obispo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to San Luis Obispo (TYS to SBP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to San Luis Obispo

Fastest flight time

6h 54m

Direct flights

None
The fastest flight from Knoxville to San Luis Obispo takes 6h 54m
There are no direct flights from Knoxville to San Luis Obispo. There are no popular flight routes from Knoxville to San Luis Obispo.
Search flight deals

Frequently asked questions about flying from Knoxville to San Luis Obispo

  • How far is Knoxville McGhee Tyson to San Luis Obispo County by plane?

    San Luis Obispo County is 2050.2 mi away from Knoxville McGhee Tyson. Flights usually cover this in 6h 54m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to San Luis Obispo County Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to San Luis Obispo County Airport are updated daily.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to San Luis Obispo County Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to San Luis Obispo County Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to San Luis Obispo County Airport.

  • What documentation or ID do you need to fly to San Luis Obispo County Airport?

    The required travel and health documents for your San Luis Obispo County Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Luis Obispo County Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Knoxville to San Luis Obispo?

Best airlines flying from Knoxville to San Luis Obispo

Compare and see reviews for airlines that fly from Knoxville to San Luis Obispo with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $308Free CancellationRating
7.1
11,660 reviews
Search American Airlines flights
United AirlinesPriceFrom $402Free CancellationRating
7.4
9,830 reviews
Search United Airlines flights

Traveling to a place near San Luis Obispo?

Book flights to San Luis Obispo if you plan to visit one of these locations
Pismo Beach
Paso Robles
Morro Bay
Cambria
Avila Beach
San Simeon
Cayucos
Arroyo Grande
Atascadero
Grover Beach

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to San Luis Obispo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Luis Obispo from Knoxville.

Can I find flights from Knoxville to San Luis Obispo with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Luis Obispo from Knoxville with this policy.

How can momondo help me find flights from Knoxville to San Luis Obispo?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to San Luis Obispo from Knoxville.

I’m not ready to book a flight from Knoxville to San Luis Obispo right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Knoxville to San Luis Obispo flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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