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Cheap flights from Indianapolis to Los Angeles from $80

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indianapolis to Los Angeles departing on 4/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
8:39 pm - 9:09 am
IND
-
SNA
15h 30m
1 stop
Frontier Logo
9:54 am - 7:54 pm
SNA
-
IND
7h 00m
1 stop
$185Frontier
Wed, May 13 - Mon, May 18
Frontier Logo
8:39 pm - 9:09 am
IND
-
SNA
15h 30m
1 stop
Frontier Logo
9:54 am - 7:54 pm
SNA
-
IND
7h 00m
1 stop
$196Frontier
Wed, May 13 - Mon, May 18
Frontier Logo
8:46 pm - 10:44 am
IND
-
SNA
16h 58m
1 stop
Frontier Logo
7:56 pm - 12:57 pm
SNA
-
IND
14h 01m
1 stop
$210Frontier
Thu, Apr 23 - Sun, Apr 26
Multiple Airlines Logo
8:25 am - 5:56 pm
IND
-
SNA
12h 31m
1 stop
Multiple Airlines Logo
7:56 pm - 11:17 am
SNA
-
IND
36h 21m
2 stops
$212Multiple Airlines
Mon, Apr 27 - Fri, May 1
Multiple Airlines Logo
1:52 pm - 3:33 pm
IND
-
SNA
28h 41m
1 stop
Multiple Airlines Logo
12:10 pm - 11:17 am
SNA
-
IND
20h 07m
2 stops
$214Multiple Airlines
Mon, Apr 20 - Sat, Apr 25
Multiple Airlines Logo
1:52 pm - 3:33 pm
IND
-
SNA
28h 41m
1 stop
Multiple Airlines Logo
12:10 pm - 7:56 pm
SNA
-
IND
28h 46m
1 stop
$215Multiple Airlines
Mon, Apr 20 - Sat, Apr 25
Frontier Logo
8:46 pm - 10:44 am
IND
-
SNA
16h 58m
1 stop
Frontier Logo
7:56 pm - 12:57 pm
SNA
-
IND
14h 01m
1 stop
$216Frontier
Thu, Apr 16 - Sun, Apr 19
Multiple Airlines Logo
9:00 am - 7:40 pm
IND
-
SNA
13h 40m
1 stop
Multiple Airlines Logo
11:29 am - 8:00 pm
SNA
-
IND
29h 31m
1 stop
$226Multiple Airlines
Mon, Apr 13 - Thu, Apr 16
Multiple Airlines Logo
9:00 am - 7:40 pm
IND
-
SNA
13h 40m
1 stop
Multiple Airlines Logo
11:29 am - 10:32 am
SNA
-
IND
20h 03m
2 stops
$227Multiple Airlines
Mon, Apr 13 - Thu, Apr 16
Multiple Airlines Logo
9:00 am - 7:40 pm
IND
-
SNA
13h 40m
1 stop
Multiple Airlines Logo
12:10 pm - 11:17 am
SNA
-
IND
20h 07m
2 stops
$231Multiple Airlines
Mon, Apr 13 - Sat, Apr 25

Spirit Airlines flights from Indianapolis to Santa Ana

Our best Spirit Airlines deals on Indianapolis to Santa Ana flight tickets
Spirit Airlines
May 11
IND6:39 pmIndianapolis
6h 06m
1 stop
SNA9:45 pmSanta Ana J. Wayne/Orange Cnty
May 14
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
7h 59m
1 stop
IND5:44 pmIndianapolis
$270
Spirit Airlines
Apr 16
IND6:39 pmIndianapolis
6h 06m
1 stop
SNA9:45 pmSanta Ana J. Wayne/Orange Cnty
Apr 23
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
7h 59m
1 stop
IND5:44 pmIndianapolis
$281
Spirit Airlines
Apr 30
IND6:39 pmIndianapolis
6h 06m
1 stop
SNA9:45 pmSanta Ana J. Wayne/Orange Cnty
May 8
SNA9:00 amSanta Ana J. Wayne/Orange Cnty
5h 44m
1 stop
IND5:44 pmIndianapolis
$283

Southwest flights from Indianapolis to Santa Ana

Our best Southwest deals on Indianapolis to Santa Ana flight tickets
Southwest
Apr 21
IND1:55 pmIndianapolis
8h 10m
2 stops
SNA7:05 pmSanta Ana J. Wayne/Orange Cnty
Apr 28
SNA11:10 amSanta Ana J. Wayne/Orange Cnty
8h 45m
1 stop
IND10:55 pmIndianapolis
$276
Southwest
Apr 22
IND6:50 amIndianapolis
8h 25m
2 stops
SNA12:15 pmSanta Ana J. Wayne/Orange Cnty
Apr 29
SNA12:55 pmSanta Ana J. Wayne/Orange Cnty
8h 15m
2 stops
IND12:10 amIndianapolis
$280
Southwest
Apr 9
IND3:05 pmIndianapolis
9h 05m
1 stop
SNA9:10 pmSanta Ana J. Wayne/Orange Cnty
Apr 14
SNA12:55 pmSanta Ana J. Wayne/Orange Cnty
8h 20m
1 stop
IND12:15 amIndianapolis
$433

momondo Fare Finder

 
Customize your flight search to find flights from Indianapolis to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 26, 2026.
Use the filters below to find and compare flights from Indianapolis to Santa Ana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

IndianapolisSanta Ana

IND - SNA

INDSNA

Indianapolis

Wed 5/13

8:39 pm-9:09 am

1 stop15h 30m

Santa Ana J. Wayne/Orange Cnty

Mon 5/18

9:54 am-7:54 pm

1 stop7h 00m

$185

IndianapolisSanta Ana

IND - SNA

INDSNA

Indianapolis

Wed 5/13

8:39 pm-9:09 am

1 stop15h 30m

Santa Ana J. Wayne/Orange Cnty

Mon 5/18

9:54 am-7:54 pm

1 stop7h 00m

$196

IndianapolisSanta Ana

IND - SNA

INDSNA

Indianapolis

Thu 4/23

8:46 pm-10:44 am

1 stop16h 58m

Santa Ana J. Wayne/Orange Cnty

Sun 4/26

7:56 pm-12:57 pm

1 stop14h 01m

$210

IndianapolisSanta Ana

IND - SNA

INDSNA

Indianapolis

Mon 4/27

8:25 am-5:56 pm

1 stop12h 31m

Santa Ana J. Wayne/Orange Cnty

Fri 5/1

7:56 pm-11:17 am

2 stops36h 21m

$212

IndianapolisSanta Ana

IND - SNA

INDSNA

Indianapolis

Mon 4/20

1:52 pm-3:33 pm

1 stop28h 41m

Santa Ana J. Wayne/Orange Cnty

Sat 4/25

12:10 pm-11:17 am

2 stops20h 07m

$214

IndianapolisSanta Ana

IND - SNA

INDSNA

Indianapolis

Mon 4/20

1:52 pm-3:33 pm

1 stop28h 41m

Santa Ana J. Wayne/Orange Cnty

Sat 4/25

12:10 pm-7:56 pm

1 stop28h 46m

$215

IndianapolisSanta Ana

IND - SNA

INDSNA

Indianapolis

Thu 4/16

8:46 pm-10:44 am

1 stop16h 58m

Santa Ana J. Wayne/Orange Cnty

Sun 4/19

7:56 pm-12:57 pm

1 stop14h 01m

$216

IndianapolisSanta Ana

IND - SNA

INDSNA

Indianapolis

Mon 4/13

9:00 am-7:40 pm

1 stop13h 40m

Santa Ana J. Wayne/Orange Cnty

Thu 4/16

11:29 am-8:00 pm

1 stop29h 31m

$226

IndianapolisSanta Ana

IND - SNA

INDSNA

Indianapolis

Mon 4/13

9:00 am-7:40 pm

1 stop13h 40m

Santa Ana J. Wayne/Orange Cnty

Thu 4/16

11:29 am-10:32 am

2 stops20h 03m

$227

IndianapolisSanta Ana

IND - SNA

INDSNA

Indianapolis

Mon 4/13

9:00 am-7:40 pm

1 stop13h 40m

Santa Ana J. Wayne/Orange Cnty

Sat 4/25

12:10 pm-11:17 am

2 stops20h 07m

$231

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Indianapolis to Santa Ana

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Indianapolis and Santa Ana?

What is the cheapest month to fly to Santa Ana?

The cheapest month to fly to Santa Ana from Indianapolis is in September. Flight prices, which tend to average around $343, are often lower during this time because this is during the off-season. The month of August is another great option to travel to Santa Ana, with average flight prices from Indianapolis averaging around $364.

How far in advance should I book a flight to Santa Ana?

You are more likely to see cheaper flights to Santa Ana from Indianapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to Santa Ana for around $425 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santa Ana from Indianapolis for as low as $309 on momondo.

How have Indianapolis to Santa Ana flight prices changed over time?

As of March 2026, prices for Indianapolis to Santa Ana flights are approximately 117% more expensive when compared to flights at the same time last year.

When to book flights from Indianapolis to Santa Ana

Are you open to changing your travel dates? Check out the ideal times to fly from Indianapolis to Santa Ana according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Indianapolis to Santa Ana (IND to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to Santa Ana

Fastest flight time

5h 57m

Direct flights

None
The fastest flight from Indianapolis to Santa Ana takes 5h 57m
There are no direct flights from Indianapolis to Santa Ana. There are no popular flight routes from Indianapolis to Santa Ana.
Search flight deals

  • How far is Indianapolis to Santa Ana J. Wayne/Orange Cnty by plane?

    There are 1792.7 mi between Indianapolis and Santa Ana J. Wayne/Orange Cnty. Flights usually cover this in 5h 57m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Indianapolis Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Indianapolis Airport to Santa Ana J. Wayne/Orange Cnty Airport were last updated today.

  • How many operators does momondo search for flights from Indianapolis Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Indianapolis Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Indianapolis Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The required travel and health documents for your Santa Ana J. Wayne/Orange Cnty Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santa Ana J. Wayne/Orange Cnty Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Indianapolis to Santa Ana?

Best airlines flying from Indianapolis to Santa Ana

Compare and see reviews for airlines that fly from Indianapolis to Santa Ana with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $141Free CancellationRating
6.3
8,547 reviews
Search Spirit Airlines flights
FrontierPriceFrom $190Free CancellationRating
5.7
3,015 reviews
Search Frontier flights
DeltaPriceFrom $271Free CancellationRating
7.9
8,339 reviews
Search Delta flights
United AirlinesPriceFrom $274Free CancellationRating
7.4
9,489 reviews
Search United Airlines flights
American AirlinesPriceFrom $286Free CancellationRating
7.1
11,499 reviews
Search American Airlines flights
SouthwestPriceFrom $301Free CancellationRating
8.0
4,331 reviews
Search Southwest flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to Santa Ana?

Finding the right flight to Santa Ana from Indianapolis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santa Ana quick and easy, saving you time and money.

Can I find flights from Indianapolis to Santa Ana with flexible booking policies on momondo?

Flights from Indianapolis to Santa Ana with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Indianapolis to Santa Ana?

momondo helps you find the best flight between Indianapolis and Santa Ana by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Indianapolis to Santa Ana right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Indianapolis to Santa Ana flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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