Cheap flights from Indiana to San Francisco from $118

If you aren’t able to travel to San Francisco during the month of April, then flying in August is also cheap. Prices for this month can be found on momondo for an average of $107.

The cheapest day to depart from Indiana to San Francisco is on a Friday when prices can be found for as low as $464. The most expensive day to fly to San Francisco is Monday, with ticket prices averaging around $728.

Our data shows that the cheapest Indiana to San Francisco flights are usually those with departure times in the morning. Our users have found flights to San Francisco in the morning for as low as $504. Flights in the evening are often more expensive with an average ticket price of $1,057.

Fly from Indianapolis to San Francisco for the best Indiana - San Francisco flight prices

You are more likely to see cheaper flights to San Francisco from Indiana when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $388 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Indiana for as low as $307 on momondo.

Delta, Southwest, and Breeze Airways are the most popular carriers operating from Indiana to San Francisco

United Airlines, Southwest and Delta are the top three most popular airlines that fly to San Francisco from Indiana according to our data. United Airlines is the first choice among our users, with 58% of people opting to fly with this airline when traveling to San Francisco. Keep in mind that there are 6 different airlines that fly to San Francisco on a routine basis, so you have a few additional options to choose from.

As of May 2026, there are 65 flights per day flying from Indiana to San Francisco. The most common time of day flights depart is 9:00AM, with 58% of flights taking off at noon.

456 flights are operational weekly from Indiana to San Francisco as of May 2026. The most popular departure day for this route is Sat, with 20% of flights per week taking off on this day.