Cheap flights from Indiana to San Francisco from $191

If you aren’t able to travel to San Francisco during the month of April, then flying in September is also cheap. Prices for this month can be found on momondo for an average of $392.

The cheapest day to depart from Indiana to San Francisco is on a Thursday when prices can be found for as low as $448. The most expensive day to fly to San Francisco is Monday, with ticket prices averaging around $776.

Our data shows that the cheapest Indiana to San Francisco flights are usually those with departure times in the afternoon. Our users have found flights to San Francisco in the afternoon for as low as $475. Flights in the evening are often more expensive with an average ticket price of $1,010.

Fly from South Bend/Michiana to San Francisco for the best Indiana - San Francisco flight prices

You are more likely to see cheaper flights to San Francisco from Indiana when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $416 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Indiana for as low as $308 on momondo.

There are 4 cabin classes available to choose from on Indiana to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Frontier, Southwest, and American Airlines are the most popular carriers operating from Indiana to San Francisco

United Airlines, Southwest and American Airlines are the top three most popular airlines that fly to San Francisco from Indiana according to our data. United Airlines is the first choice among our users, with 60% of people opting to fly with this airline when traveling to San Francisco. Keep in mind that there are 6 different airlines that fly to San Francisco on a routine basis, so you have a few additional options to choose from.

As of October 2026, there are 2 flights per day flying from Indiana to San Francisco. The most common time of day flights depart is 6:00AM, with 89% of flights taking off at noon.

18 flights are operational weekly from Indiana to San Francisco as of October 2026. The most popular departure day for this route is Wed, with 39% of flights per week taking off on this day.