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Cheap flights from Florence, South Carolina to San Antonio from $503

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Florence, South Carolina to San Antonio departing on 9/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Florence, South Carolina to San Antonio

Cheap round-trip flights

American Airlines Logo
4:57 pm - 10:00 pmFLO-SAT
6h 03m1 stop
American Airlines Logo
8:10 am - 4:32 pmSAT-FLO
7h 22m1 stop
$503American Airlines
Find Deal
Thu, Sep 11 - Sun, Sep 14
American Airlines Logo
11:18 am - 4:30 pmFLO-SAT
6h 12m1 stop
American Airlines Logo
5:00 am - 4:32 pmSAT-FLO
10h 32m2 stops
$508American Airlines
Find Deal
Thu, Sep 11 - Sun, Sep 14
American Airlines Logo
11:18 am - 8:51 pmFLO-SAT
10h 33m2 stops
American Airlines Logo
6:00 am - 4:32 pmSAT-FLO
9h 32m2 stops
$513American Airlines
Find Deal
Thu, Sep 11 - Sun, Sep 14
American Airlines Logo
6:33 pm - 10:44 pmFLO-SAT
5h 11m1 stop
American Airlines Logo
8:43 am - 2:08 pmSAT-FLO
4h 25m1 stop
$579American Airlines
Find Deal
Mon, Dec 1 - Wed, Dec 3
American Airlines Logo
6:33 pm - 10:44 pmFLO-SAT
5h 11m1 stop
American Airlines Logo
12:31 pm - 11:40 pmSAT-FLO
10h 09m2 stops
$584American Airlines
Find Deal
Mon, Dec 1 - Wed, Dec 3
American Airlines Logo
11:11 am - 9:59 pmFLO-SAT
11h 48m2 stops
American Airlines Logo
5:04 am - 2:08 pmSAT-FLO
8h 04m2 stops
$843American Airlines
Find Deal
Mon, Dec 1 - Wed, Dec 3

American Airlines flights from Florence, South Carolina to San Antonio

Our best American Airlines deals on Florence, South Carolina to San Antonio flight tickets
American Airlines
Sep 11
FLO4:57 pmFlorence
6h 03m
1 stop
SAT10:00 pmSan Antonio
Sep 14
SAT8:10 amSan Antonio
7h 22m
1 stop
FLO4:32 pmFlorence
$503
Find similar
American Airlines
Sep 11
FLO11:18 amFlorence
6h 12m
1 stop
SAT4:30 pmSan Antonio
Sep 14
SAT5:00 amSan Antonio
10h 32m
2 stops
FLO4:32 pmFlorence
$508
Find similar
American Airlines
Sep 11
FLO11:18 amFlorence
10h 33m
2 stops
SAT8:51 pmSan Antonio
Sep 14
SAT6:00 amSan Antonio
9h 32m
2 stops
FLO4:32 pmFlorence
$513
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Florence, South Carolina to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 25, 2025.
Use the filters below to find and compare flights from Florence, South Carolina to San Antonio that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

FlorenceSan Antonio

FLO - SAT

FLOSAT

Florence

Thu 9/11

4:57 pm-10:00 pm

1 stop6h 03m

San Antonio

Sun 9/14

8:10 am-4:32 pm

1 stop7h 22m

$503

FlorenceSan Antonio

FLO - SAT

FLOSAT

Florence

Thu 9/11

11:18 am-4:30 pm

1 stop6h 12m

San Antonio

Sun 9/14

5:00 am-4:32 pm

2 stops10h 32m

$508

FlorenceSan Antonio

FLO - SAT

FLOSAT

Florence

Thu 9/11

11:18 am-8:51 pm

2 stops10h 33m

San Antonio

Sun 9/14

6:00 am-4:32 pm

2 stops9h 32m

$513

FlorenceSan Antonio

FLO - SAT

FLOSAT

Florence

Mon 12/1

6:33 pm-10:44 pm

1 stop5h 11m

San Antonio

Wed 12/3

8:43 am-2:08 pm

1 stop4h 25m

$579

FlorenceSan Antonio

FLO - SAT

FLOSAT

Florence

Mon 12/1

6:33 pm-10:44 pm

1 stop5h 11m

San Antonio

Wed 12/3

12:31 pm-11:40 pm

2 stops10h 09m

$584

FlorenceSan Antonio

FLO - SAT

FLOSAT

Florence

Mon 12/1

11:11 am-9:59 pm

2 stops11h 48m

San Antonio

Wed 12/3

5:04 am-2:08 pm

2 stops8h 04m

$843

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to San Antonio from

How to get the cheapest flight ticket from Florence, South Carolina to San Antonio

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to San Antonio?

American Airlines, Delta and Southwest are the top three most popular airlines that fly to San Antonio from Florence, South Carolina according to our data. American Airlines is the first choice among our users, with 66% of people opting to fly with this airline when traveling to San Antonio. Keep in mind that there are 6 different airlines that fly to San Antonio on a routine basis, so you have a few additional options to choose from.

When to book flights from Florence, South Carolina to San Antonio

Are you open to changing your travel dates? Check out the ideal times to fly from Florence, South Carolina to San Antonio according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Florence, South Carolina to San Antonio (FLO to SAT) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Florence, South Carolina to San Antonio

Direct flights

None
There are no direct flights from Florence, South Carolina to San Antonio. There are no popular flight routes from Florence, South Carolina to San Antonio.
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  • How far is Florence to San Antonio by plane?

    San Antonio is 1145.4 mi away from Florence. In terms of flight time, this usually takes a little over 5h 11m.

  • When did momondo last update prices for flights from Florence Airport to San Antonio Airport?

    Prices for flights from Florence Airport to San Antonio Airport refresh daily.

  • How old do you have to be to fly from Florence Airport to San Antonio Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Florence Airport to San Antonio Airport.

  • What documentation or ID do you need to fly to San Antonio Airport?

    The travel and health documents required for your trip to San Antonio Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at San Antonio Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near San Antonio?

Book flights to San Antonio if you plan to visit one of these locations
New Braunfels
Kerrville
Boerne
Schertz
Pleasanton

Why use momondo?

Why should I use momondo to find a flight deal from Florence to San Antonio?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Florence to San Antonio for you.

Can I find flights from Florence to San Antonio with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Antonio from Florence which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Florence to San Antonio?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to San Antonio from Florence.

I’m not ready to book a flight from Florence to San Antonio right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Florence to San Antonio flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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