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Cheap flights from Des Moines to San Jose from $284

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to San Jose departing on 11/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Des Moines to San Jose

Cheap round-trip flights

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American Airlines Logo
6:17 pm - 10:49 pmDSM-SJC
6h 32m1 stop
American Airlines Logo
9:55 am - 8:04 pmSJC-DSM
8h 09m1 stop
$353American Airlines
Find Deal
Thu, Jan 15 - Tue, Jan 20
Delta Logo
10:54 am - 9:20 pmDSM-SJC
12h 26m2 stops
Delta Logo
10:30 pm - 10:41 amSJC-DSM
10h 11m1 stop
$358Delta
Find Deal
Thu, Jan 15 - Tue, Jan 20
Delta Logo
10:54 am - 9:20 pmDSM-SJC
12h 26m2 stops
Delta Logo
8:05 pm - 10:51 amSJC-DSM
12h 46m2 stops
$363Delta
Find Deal
Thu, Jan 15 - Tue, Jan 20
United Airlines Logo
9:00 am - 1:32 pmDSM-SJC
6h 32m1 stop
United Airlines Logo
8:45 am - 9:37 pmSJC-DSM
10h 52m2 stops
$423United Airlines
Find Deal
Fri, Dec 5 - Mon, Dec 8
United Airlines Logo
9:03 am - 1:39 pmDSM-SJC
6h 36m1 stop
United Airlines Logo
4:00 pm - 11:44 pmSJC-DSM
5h 44m1 stop
$447United Airlines
Find Deal
Fri, Jan 9 - Fri, Jan 16
Multiple Airlines Logo
2:17 pm - 5:34 pmDSM-SJC
29h 17m1 stop
Multiple Airlines Logo
12:42 pm - 7:24 pmSJC-DSM
28h 42m2 stops
$475Multiple Airlines
Find Deal
Sun, Nov 9 - Sat, Nov 22
Multiple Airlines Logo
8:19 pm - 3:55 pmDSM-SJC
21h 36m2 stops
Multiple Airlines Logo
4:20 pm - 11:26 amSJC-DSM
17h 06m1 stop
$482Multiple Airlines
Find Deal
Sun, Nov 23 - Sun, Nov 30
Alaska Airlines Logo
5:10 am - 12:16 pmDSM-SJC
9h 06m1 stop
Alaska Airlines Logo
9:57 am - 8:06 pmSJC-DSM
8h 09m1 stop
$595Alaska Airlines
Find Deal
Tue, Nov 25 - Tue, Dec 2
Southwest Logo
6:35 am - 2:10 pmDSM-SJC
9h 35m2 stops
Southwest Logo
4:10 pm - 11:10 pmSJC-DSM
5h 00m1 stop
$602Southwest
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Fri, Dec 26 - Tue, Dec 30
Southwest Logo
6:35 am - 2:10 pmDSM-SJC
9h 35m2 stops
Southwest Logo
1:50 pm - 12:05 amSJC-DSM
8h 15m2 stops
$657Southwest
Find Deal
Fri, Dec 26 - Tue, Dec 30

American Airlines flights from Des Moines to San Jose, California

Our best American Airlines deals on Des Moines to San Jose, California flight tickets
American Airlines
Jan 15
DSM6:17 pmDes Moines
6h 32m
1 stop
SJC10:49 pmSan Jose
Jan 20
SJC9:55 amSan Jose
8h 09m
1 stop
DSM8:04 pmDes Moines
$353
Find similar
American Airlines
Jan 15
DSM6:17 pmDes Moines
6h 32m
1 stop
SJC10:49 pmSan Jose
Jan 18
SJC2:18 pmSan Jose
7h 40m
1 stop
DSM11:58 pmDes Moines
$374
Find similar
American Airlines
Jan 15
DSM4:00 pmDes Moines
8h 49m
2 stops
SJC10:49 pmSan Jose
Jan 18
SJC2:32 pmSan Jose
6h 51m
1 stop
DSM11:23 pmDes Moines
$379
Find similar

Delta flights from Des Moines to San Jose, California

Our best Delta deals on Des Moines to San Jose, California flight tickets
Delta
Jan 15
DSM10:54 amDes Moines
12h 26m
2 stops
SJC9:20 pmSan Jose
Jan 20
SJC10:30 pmSan Jose
10h 11m
1 stop
DSM10:41 amDes Moines
$358
Find similar
Delta
Jan 15
DSM10:54 amDes Moines
12h 26m
2 stops
SJC9:20 pmSan Jose
Jan 20
SJC8:05 pmSan Jose
12h 46m
2 stops
DSM10:51 amDes Moines
$363
Find similar
Delta
Dec 5
DSM2:59 pmDes Moines
10h 54m
2 stops
SJC11:53 pmSan Jose
Dec 8
SJC10:25 pmSan Jose
13h 54m
2 stops
DSM2:19 pmDes Moines
$428
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to San Jose, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Des Moines to San Jose, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Thu 1/15

6:17 pm-10:49 pm

1 stop6h 32m

San Jose

Tue 1/20

9:55 am-8:04 pm

1 stop8h 09m

$353

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Thu 1/15

10:54 am-9:20 pm

2 stops12h 26m

San Jose

Tue 1/20

10:30 pm-10:41 am

1 stop10h 11m

$358

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Thu 1/15

10:54 am-9:20 pm

2 stops12h 26m

San Jose

Tue 1/20

8:05 pm-10:51 am

2 stops12h 46m

$363

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Fri 12/5

9:00 am-1:32 pm

1 stop6h 32m

San Jose

Mon 12/8

8:45 am-9:37 pm

2 stops10h 52m

$423

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Fri 1/9

9:03 am-1:39 pm

1 stop6h 36m

San Jose

Fri 1/16

4:00 pm-11:44 pm

1 stop5h 44m

$447

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Sun 11/9

2:17 pm-5:34 pm

1 stop29h 17m

San Jose

Sat 11/22

12:42 pm-7:24 pm

2 stops28h 42m

$475

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Sun 11/23

8:19 pm-3:55 pm

2 stops21h 36m

San Jose

Sun 11/30

4:20 pm-11:26 am

1 stop17h 06m

$482

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Tue 11/25

5:10 am-12:16 pm

1 stop9h 06m

San Jose

Tue 12/2

9:57 am-8:06 pm

1 stop8h 09m

$595

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Fri 12/26

6:35 am-2:10 pm

2 stops9h 35m

San Jose

Tue 12/30

4:10 pm-11:10 pm

1 stop5h 00m

$602

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Fri 12/26

6:35 am-2:10 pm

2 stops9h 35m

San Jose

Tue 12/30

1:50 pm-12:05 am

2 stops8h 15m

$657

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Jose from

How to get the cheapest flight ticket from Des Moines to San Jose, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Jose, California?

The month of August is, on average, the cheapest month to fly to San Jose, California from Des Moines, with most prices found around $367. If you are unable to visit San Jose, California during the month of August, then departing from Des Moines during the month April is also very affordable. Most momondo users find prices during this month for around $374.

What is the cheapest day to depart on your flight to San Jose, California?

On average, the least expensive day to fly to San Jose, California from Des Moines is on a Friday. momondo users have found tickets for Friday departures for as low as $407. However, this price may fluctuate depending on the airline, the season, and holidays. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from Des Moines to San Jose, California for around $546.

What is the cheapest time of day to depart on your flight to San Jose, California?

The cheapest time of day to fly to San Jose, California is in the morning when flights can be purchased for as low as $436. In the afternoon is when there is more demand to fly to San Jose, California, so prices are often more expensive at around $482 per ticket.

When to book flights from Des Moines to San Jose, California

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to San Jose, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to San Jose, California (DSM to SJC) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to San Jose, California

Direct flights

None
There are no direct flights from Des Moines to San Jose, California. There are no popular flight routes from Des Moines to San Jose, California.
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  • How far is Des Moines to San Jose by plane?

    The straight-line distance from Des Moines to San Jose is 1527.5 mi. 6h 03m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to San Jose Airport?

    Prices for flights from Des Moines Airport to San Jose Airport are updated daily.

  • How many operators does momondo search for flights from Des Moines Airport to San Jose Airport?

  • How old do you have to be to fly from Des Moines Airport to San Jose Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to San Jose Airport.

  • What documentation or ID do you need to fly to San Jose Airport?

    The travel and health documents you'll need for your trip to San Jose Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Jose Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to San Jose, California?

Best airlines flying from Des Moines to San Jose, California

Compare and see reviews for airlines that fly from Des Moines to San Jose, California with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $296Free CancellationRating
7.2
11,040 reviews
Search American Airlines flights
United AirlinesPriceFrom $296Free CancellationRating
7.4
9,007 reviews
Search United Airlines flights
DeltaPriceFrom $302Free CancellationRating
7.9
8,001 reviews
Search Delta flights
SouthwestPriceFrom $367Free CancellationRating
8.0
4,241 reviews
Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to San Jose?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Des Moines to San Jose. momondo saves you time and could save you money on your trip.

Can I find flights from Des Moines to San Jose with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Jose from Des Moines with this policy.

How can momondo help me find flights from Des Moines to San Jose?

momondo provides multiple filters to help you find the best flight to San Jose from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to San Jose right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to San Jose flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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