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Cheap flights from Des Moines to San Jose from $185

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to San Jose departing on 9/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to San Jose

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
9:56 pm - 12:43 pmDSM  Des Moines-SJC San Jose
16h 47m1 stop Las Vegas Harry Reid Intl
Multiple Airlines Logo
10:47 pm - 7:33 pmSJC  San Jose-DSM Des Moines
18h 46m2 stops Las Vegas Harry Reid Intl Denver Intl
$278Multiple Airlines
Sun, Sep 20 - Sun, Sep 27
Delta Logo
10:59 am - 5:34 pmDSM  Des Moines-SJC San Jose
8h 35m1 stop Minneapolis St Paul
Delta Logo
6:10 am - 2:04 pmSJC  San Jose-DSM Des Moines
5h 54m1 stop Minneapolis St Paul
$369Delta
Sat, Sep 5 - Sun, Sep 6
Frontier Logo
11:29 am - 12:43 pmDSM  Des Moines-SJC San Jose
27h 14m2 stops Denver Intl Las Vegas Harry Reid Intl
Frontier Logo
10:47 pm - 7:33 pmSJC  San Jose-DSM Des Moines
18h 46m2 stops Las Vegas Harry Reid Intl Denver Intl
$370Frontier
Sun, Sep 20 - Sun, Sep 27
American Airlines Logo
5:30 am - 11:57 amDSM  Des Moines-SJC San Jose
8h 27m1 stop Phoenix Sky Harbor Intl
American Airlines Logo
12:42 pm - 8:46 pmSJC  San Jose-DSM Des Moines
6h 04m1 stop Phoenix Sky Harbor Intl
$379American Airlines
Thu, Sep 3 - Sat, Sep 5
American Airlines Logo
5:30 am - 11:57 amDSM  Des Moines-SJC San Jose
8h 27m1 stop Phoenix Sky Harbor Intl
American Airlines Logo
4:00 pm - 11:59 pmSJC  San Jose-DSM Des Moines
5h 59m1 stop Phoenix Sky Harbor Intl
$381American Airlines
Tue, Sep 1 - Sat, Sep 12
United Airlines Logo
11:33 am - 5:31 pmDSM  Des Moines-SJC San Jose
7h 58m1 stop Denver Intl
United Airlines Logo
8:45 am - 9:23 pmSJC  San Jose-DSM Des Moines
10h 38m2 stops Denver Intl Chicago O'Hare Intl
$384United Airlines
Thu, Sep 3 - Sat, Sep 5
American Airlines Logo
5:30 am - 11:57 amDSM  Des Moines-SJC San Jose
8h 27m1 stop Phoenix Sky Harbor Intl
American Airlines Logo
12:42 pm - 11:16 pmSJC  San Jose-DSM Des Moines
8h 34m2 stops Phoenix Sky Harbor Intl Dallas/Fort Worth
$384American Airlines
Thu, Sep 3 - Sat, Sep 5
Southwest Logo
7:00 am - 10:35 amDSM  Des Moines-SJC San Jose
5h 35m1 stop Denver Intl
Southwest Logo
8:40 am - 5:45 pmSJC  San Jose-DSM Des Moines
7h 05m1 stop Las Vegas Harry Reid Intl
$389Southwest
Mon, Aug 31 - Wed, Sep 9
Southwest Logo
6:40 pm - 10:20 pmDSM  Des Moines-SJC San Jose
5h 40m1 stop Denver Intl
Southwest Logo
8:40 am - 5:45 pmSJC  San Jose-DSM Des Moines
7h 05m1 stop Las Vegas Harry Reid Intl
$389Southwest
Tue, Sep 29 - Wed, Sep 30
United Airlines Logo
5:21 pm - 8:57 pmDSM  Des Moines-SJC San Jose
5h 36m1 stop Denver Intl
United Airlines Logo
8:45 am - 4:19 pmSJC  San Jose-DSM Des Moines
5h 34m1 stop Denver Intl
$473United Airlines
Wed, Sep 9 - Sat, Sep 12

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American Airlines flights from Des Moines to San Jose, California

Our best American Airlines deals on Des Moines to San Jose, California flight tickets
American Airlines
Sep 3
DSM5:30 amDes Moines
8h 27m
1 stop
SJC11:57 amSan Jose
Sep 8
SJC6:00 amSan Jose
5h 29m
1 stop
DSM1:29 pmDes Moines
$397
American Airlines
Sep 10
DSM5:39 pmDes Moines
6h 52m
1 stop
SJC10:31 pmSan Jose
Sep 13
SJC6:00 amSan Jose
5h 47m
1 stop
DSM1:47 pmDes Moines
$425
American Airlines
Sep 24
DSM2:44 pmDes Moines
9h 47m
2 stops
SJC10:31 pmSan Jose
Sep 29
SJC6:00 amSan Jose
9h 52m
2 stops
DSM5:52 pmDes Moines
$427

United Airlines flights from Des Moines to San Jose, California

Our best United Airlines deals on Des Moines to San Jose, California flight tickets
United Airlines
Aug 20
DSM6:00 amDes Moines
7h 46m
1 stop
SJC11:46 amSan Jose
Aug 24
SJC8:45 amSan Jose
5h 34m
1 stop
DSM4:19 pmDes Moines
$493
United Airlines
Aug 13
DSM6:00 amDes Moines
13h 31m
2 stops
SJC5:31 pmSan Jose
Aug 16
SJC6:37 pmSan Jose
13h 49m
3 stops
DSM10:26 amDes Moines
$2,106

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to San Jose, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 7, 2026.
Use the filters below to find and compare flights from Des Moines to San Jose, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesSan Jose

DSM Des Moines - SJC San Jose

DSMSJC

Des Moines

Sun 9/20

9:56 pm-12:43 pm

1 stop16h 47m

San Jose

Sun 9/27

10:47 pm-7:33 pm

2 stops18h 46m

$278

Des MoinesSan Jose

DSM Des Moines - SJC San Jose

DSMSJC

Des Moines

Sat 9/5

10:59 am-5:34 pm

1 stop8h 35m

San Jose

Sun 9/6

6:10 am-2:04 pm

1 stop5h 54m

$369

Des MoinesSan Jose

DSM Des Moines - SJC San Jose

DSMSJC

Des Moines

Sun 9/20

11:29 am-12:43 pm

2 stops27h 14m

San Jose

Sun 9/27

10:47 pm-7:33 pm

2 stops18h 46m

$370

Des MoinesSan Jose

DSM Des Moines - SJC San Jose

DSMSJC

Des Moines

Thu 9/3

5:30 am-11:57 am

1 stop8h 27m

San Jose

Sat 9/5

12:42 pm-8:46 pm

1 stop6h 04m

$379

Des MoinesSan Jose

DSM Des Moines - SJC San Jose

DSMSJC

Des Moines

Tue 9/1

5:30 am-11:57 am

1 stop8h 27m

San Jose

Sat 9/12

4:00 pm-11:59 pm

1 stop5h 59m

$381

Des MoinesSan Jose

DSM Des Moines - SJC San Jose

DSMSJC

Des Moines

Thu 9/3

11:33 am-5:31 pm

1 stop7h 58m

San Jose

Sat 9/5

8:45 am-9:23 pm

2 stops10h 38m

$384

Des MoinesSan Jose

DSM Des Moines - SJC San Jose

DSMSJC

Des Moines

Thu 9/3

5:30 am-11:57 am

1 stop8h 27m

San Jose

Sat 9/5

12:42 pm-11:16 pm

2 stops8h 34m

$384

Des MoinesSan Jose

DSM Des Moines - SJC San Jose

DSMSJC

Des Moines

Mon 8/31

7:00 am-10:35 am

1 stop5h 35m

San Jose

Wed 9/9

8:40 am-5:45 pm

1 stop7h 05m

$389

Des MoinesSan Jose

DSM Des Moines - SJC San Jose

DSMSJC

Des Moines

Tue 9/29

6:40 pm-10:20 pm

1 stop5h 40m

San Jose

Wed 9/30

8:40 am-5:45 pm

1 stop7h 05m

$389
Quickest round-trip

Des MoinesSan Jose

DSM Des Moines - SJC San Jose

DSMSJC

Des Moines

Wed 9/9

5:21 pm-8:57 pm

1 stop5h 36m

San Jose

Sat 9/12

8:45 am-4:19 pm

1 stop5h 34m

$473

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Des Moines to San Jose, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Des Moines and San Jose, California?

Prices are currently low for flights on this route.

Typical prices usually range from $465 to $518.
The lowest price recently found on this route was $278.

What is the cheapest month to fly to San Jose, California?

The month of February is, on average, the cheapest month to fly to San Jose, California from Des Moines, with most prices found around $367. If you are unable to visit San Jose, California during the month of February, then departing from Des Moines during the month December is also very affordable. Most momondo users find prices during this month for around $392.

When to book flights from Des Moines to San Jose, California

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to San Jose, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to San Jose, California (DSM to SJC) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to San Jose, California

Fastest flight time

5h 40m

Direct flights

None
The fastest flight from Des Moines to San Jose, California takes 5h 40m
There are no direct flights from Des Moines to San Jose, California. There are no popular flight routes from Des Moines to San Jose, California.
Search flight deals

Frequently asked questions about flying from Des Moines to San Jose, California

  • How far is Des Moines to San Jose by plane?

    The straight-line distance from Des Moines to San Jose is 1527.5 mi. 5h 40m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to San Jose Airport?

    Prices for flights from Des Moines Airport to San Jose Airport are updated daily.

  • How many operators does momondo search for flights from Des Moines Airport to San Jose Airport?

  • How old do you have to be to fly from Des Moines Airport to San Jose Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to San Jose Airport.

  • What documentation or ID do you need to fly to San Jose Airport?

    The travel and health documents you'll need for your trip to San Jose Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Jose Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to San Jose, California?

Best airlines flying from Des Moines to San Jose, California

Compare and see reviews for airlines that fly from Des Moines to San Jose, California with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $332Free CancellationRating
7.1
11,877 reviews
Search American Airlines flights
United AirlinesPriceFrom $361Free CancellationRating
7.4
10,081 reviews
Search United Airlines flights
SouthwestPriceFrom $379Free CancellationRating
8.0
4,217 reviews
Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to San Jose?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Des Moines to San Jose. momondo saves you time and could save you money on your trip.

Can I find flights from Des Moines to San Jose with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Jose from Des Moines with this policy.

How can momondo help me find flights from Des Moines to San Jose?

momondo provides multiple filters to help you find the best flight to San Jose from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to San Jose right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to San Jose flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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