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Cheap flights from Des Moines to San Jose from $179

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to San Jose departing on 5/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Des Moines to San Jose

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
6:55 am - 10:35 am
DSM
-
SJC
5h 40m
1 stop
Southwest Logo
1:15 pm - 8:55 pm
SJC
-
DSM
5h 40m
1 stop
$337Southwest
Wed, Apr 15 - Sat, Apr 18
Southwest Logo
6:55 am - 10:35 am
DSM
-
SJC
5h 40m
1 stop
Southwest Logo
7:45 am - 5:55 pm
SJC
-
DSM
8h 10m
1 stop
$352Southwest
Tue, Apr 7 - Tue, Apr 14
Southwest Logo
6:40 am - 10:20 am
DSM
-
SJC
5h 40m
1 stop
Southwest Logo
6:30 am - 1:30 pm
SJC
-
DSM
5h 00m
1 stop
$357Southwest
Sat, Apr 25 - Sat, May 2
Southwest Logo
2:10 pm - 8:50 pm
DSM
-
SJC
8h 40m
2 stops
Southwest Logo
1:15 pm - 8:55 pm
SJC
-
DSM
5h 40m
1 stop
$362Southwest
Sat, Apr 25 - Sat, May 2
Southwest Logo
2:10 pm - 8:50 pm
DSM
-
SJC
8h 40m
2 stops
Southwest Logo
9:50 am - 8:55 pm
SJC
-
DSM
9h 05m
2 stops
$367Southwest
Sat, Apr 25 - Sat, May 2
American Airlines Logo
12:03 pm - 10:59 pm
DSM
-
SJC
12h 56m
2 stops
American Airlines Logo
7:09 pm - 8:26 am
SJC
-
DSM
11h 17m
2 stops
$368American Airlines
Sat, Apr 25 - Sat, May 16
Delta Logo
2:33 pm - 11:41 pm
DSM
-
SJC
11h 08m
2 stops
Delta Logo
10:55 pm - 9:46 am
SJC
-
DSM
8h 51m
1 stop
$377Delta
Wed, May 20 - Tue, May 26
American Airlines Logo
5:19 am - 12:06 pm
DSM
-
SJC
8h 47m
1 stop
American Airlines Logo
4:25 pm - 11:46 pm
SJC
-
DSM
5h 21m
1 stop
$378American Airlines
Wed, May 20 - Tue, May 26
Delta Logo
2:33 pm - 11:41 pm
DSM
-
SJC
11h 08m
2 stops
Delta Logo
6:15 am - 8:36 pm
SJC
-
DSM
12h 21m
2 stops
$383Delta
Wed, May 20 - Tue, May 26
Southwest Logo
6:25 am - 12:25 pm
DSM
-
SJC
8h 00m
1 stop
Southwest Logo
6:00 am - 3:05 pm
SJC
-
DSM
7h 05m
1 stop
$387Southwest
Tue, Jun 23 - Tue, Jul 7

American Airlines flights from Des Moines to San Jose, California

Our best American Airlines deals on Des Moines to San Jose, California flight tickets
American Airlines
Apr 25
DSM12:03 pmDes Moines
12h 56m
2 stops
SJC10:59 pmSan Jose
May 16
SJC7:09 pmSan Jose
11h 17m
2 stops
DSM8:26 amDes Moines
$368
American Airlines
May 20
DSM5:19 amDes Moines
8h 47m
1 stop
SJC12:06 pmSan Jose
May 26
SJC4:25 pmSan Jose
5h 21m
1 stop
DSM11:46 pmDes Moines
$378
American Airlines
Apr 11
DSM5:00 amDes Moines
7h 07m
1 stop
SJC10:07 amSan Jose
Apr 18
SJC6:10 amSan Jose
5h 37m
1 stop
DSM1:47 pmDes Moines
$390

Delta flights from Des Moines to San Jose, California

Our best Delta deals on Des Moines to San Jose, California flight tickets
Delta
May 20
DSM2:33 pmDes Moines
11h 08m
2 stops
SJC11:41 pmSan Jose
May 26
SJC10:55 pmSan Jose
8h 51m
1 stop
DSM9:46 amDes Moines
$377
Delta
May 20
DSM2:33 pmDes Moines
11h 08m
2 stops
SJC11:41 pmSan Jose
May 26
SJC6:15 amSan Jose
12h 21m
2 stops
DSM8:36 pmDes Moines
$383
Delta
Apr 15
DSM2:44 pmDes Moines
10h 58m
2 stops
SJC11:42 pmSan Jose
Apr 18
SJC9:37 amSan Jose
9h 35m
2 stops
DSM9:12 pmDes Moines
$409

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to San Jose, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 15, 2026.
Use the filters below to find and compare flights from Des Moines to San Jose, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Wed 4/15

6:55 am-10:35 am

1 stop5h 40m

San Jose

Sat 4/18

1:15 pm-8:55 pm

1 stop5h 40m

$337

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Tue 4/7

6:55 am-10:35 am

1 stop5h 40m

San Jose

Tue 4/14

7:45 am-5:55 pm

1 stop8h 10m

$352
Quickest round-trip

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Sat 4/25

6:40 am-10:20 am

1 stop5h 40m

San Jose

Sat 5/2

6:30 am-1:30 pm

1 stop5h 00m

$357

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Sat 4/25

2:10 pm-8:50 pm

2 stops8h 40m

San Jose

Sat 5/2

1:15 pm-8:55 pm

1 stop5h 40m

$362

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Sat 4/25

2:10 pm-8:50 pm

2 stops8h 40m

San Jose

Sat 5/2

9:50 am-8:55 pm

2 stops9h 05m

$367

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Sat 4/25

12:03 pm-10:59 pm

2 stops12h 56m

San Jose

Sat 5/16

7:09 pm-8:26 am

2 stops11h 17m

$368

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Wed 5/20

2:33 pm-11:41 pm

2 stops11h 08m

San Jose

Tue 5/26

10:55 pm-9:46 am

1 stop8h 51m

$377

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Wed 5/20

5:19 am-12:06 pm

1 stop8h 47m

San Jose

Tue 5/26

4:25 pm-11:46 pm

1 stop5h 21m

$378

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Wed 5/20

2:33 pm-11:41 pm

2 stops11h 08m

San Jose

Tue 5/26

6:15 am-8:36 pm

2 stops12h 21m

$383

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Tue 6/23

6:25 am-12:25 pm

1 stop8h 00m

San Jose

Tue 7/7

6:00 am-3:05 pm

1 stop7h 05m

$387

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Jose from

How to get the cheapest flight ticket from Des Moines to San Jose, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Jose, California?

The month of February is, on average, the cheapest month to fly to San Jose, California from Des Moines, with most prices found around $367. If you are unable to visit San Jose, California during the month of February, then departing from Des Moines during the month August is also very affordable. Most momondo users find prices during this month for around $367.

When to book flights from Des Moines to San Jose, California

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to San Jose, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to San Jose, California (DSM to SJC) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to San Jose, California

Fastest flight time

6h 12m

Direct flights

None
The fastest flight from Des Moines to San Jose, California takes 6h 12m
There are no direct flights from Des Moines to San Jose, California. There are no popular flight routes from Des Moines to San Jose, California.
Search flight deals

  • How far is Des Moines to San Jose by plane?

    The straight-line distance from Des Moines to San Jose is 1527.5 mi. 6h 12m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to San Jose Airport?

    Prices for flights from Des Moines Airport to San Jose Airport are updated daily.

  • How many operators does momondo search for flights from Des Moines Airport to San Jose Airport?

  • How old do you have to be to fly from Des Moines Airport to San Jose Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to San Jose Airport.

  • What documentation or ID do you need to fly to San Jose Airport?

    The travel and health documents you'll need for your trip to San Jose Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Jose Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to San Jose, California?

Best airlines flying from Des Moines to San Jose, California

Compare and see reviews for airlines that fly from Des Moines to San Jose, California with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $179Free CancellationRating
7.9
8,293 reviews
Search Delta flights
American AirlinesPriceFrom $290Free CancellationRating
7.1
11,472 reviews
Search American Airlines flights
United AirlinesPriceFrom $296Free CancellationRating
7.4
9,427 reviews
Search United Airlines flights
SouthwestPriceFrom $356Free CancellationRating
8.0
4,318 reviews
Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to San Jose?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Des Moines to San Jose. momondo saves you time and could save you money on your trip.

Can I find flights from Des Moines to San Jose with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Jose from Des Moines with this policy.

How can momondo help me find flights from Des Moines to San Jose?

momondo provides multiple filters to help you find the best flight to San Jose from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to San Jose right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to San Jose flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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