Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Des Moines to San Jose from $106

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to San Jose departing on 9/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Des Moines to San Jose

Cheap round-trip flights

Delta Logo
2:15 pm - 11:01 pmDSM-SJC
10h 46m1 stop
Delta Logo
6:10 am - 2:14 pmSJC-DSM
6h 04m1 stop
$257Delta
Find Deal
Tue, Dec 9 - Sat, Dec 13
Delta Logo
2:54 pm - 11:59 pmDSM-SJC
11h 05m2 stops
Delta Logo
6:10 am - 2:14 pmSJC-DSM
6h 04m1 stop
$262Delta
Find Deal
Tue, Dec 9 - Sat, Dec 13
American Airlines Logo
5:55 pm - 10:47 pmDSM-SJC
6h 52m1 stop
American Airlines Logo
6:00 am - 2:58 pmSJC-DSM
6h 58m1 stop
$287American Airlines
Find Deal
Thu, Oct 2 - Tue, Oct 7
Logo
7:00 am - 3:21 pmDSM-SJC
34h 21m2 stops
Logo
11:40 am - 10:40 pmSJC-DSM
9h 00m1 stop
$303
Find Deal
Sun, Sep 28 - Thu, Oct 2
American Airlines Logo
5:30 am - 9:21 amDSM-SJC
5h 51m1 stop
American Airlines Logo
6:00 am - 3:03 pmSJC-DSM
7h 03m1 stop
$309American Airlines
Find Deal
Thu, Oct 16 - Wed, Oct 22
Logo
3:42 pm - 3:21 pmDSM-SJC
25h 39m1 stop
Logo
11:40 am - 10:40 pmSJC-DSM
9h 00m1 stop
$333
Find Deal
Sun, Sep 28 - Thu, Oct 2
Southwest Logo
1:05 pm - 4:50 pmDSM-SJC
5h 45m1 stop
Southwest Logo
4:10 pm - 11:10 pmSJC-DSM
5h 00m1 stop
$477Southwest
Find Deal
Wed, Nov 26 - Mon, Dec 1
Southwest Logo
1:05 pm - 4:50 pmDSM-SJC
5h 45m1 stop
Southwest Logo
6:30 am - 11:10 pmSJC-DSM
14h 40m2 stops
$498Southwest
Find Deal
Wed, Nov 26 - Mon, Dec 1
United Airlines Logo
5:45 am - 10:05 amDSM-SJC
6h 20m1 stop
United Airlines Logo
6:30 am - 1:42 amSJC-DSM
17h 12m1 stop
$546United Airlines
Find Deal
Thu, Nov 27 - Sat, Nov 29
United Airlines Logo
5:45 am - 10:05 amDSM-SJC
6h 20m1 stop
United Airlines Logo
6:30 am - 1:42 amSJC-DSM
17h 12m1 stop
$596United Airlines
Find Deal
Tue, Nov 25 - Sat, Nov 29

Delta flights from Des Moines to San Jose

Our best Delta deals on Des Moines to San Jose flight tickets
Delta
Dec 9
DSM2:15 pmDes Moines
10h 46m
1 stop
SJC11:01 pmSan Jose
Dec 13
SJC6:10 amSan Jose
6h 04m
1 stop
DSM2:14 pmDes Moines
$257
Find similar
Delta
Dec 9
DSM2:54 pmDes Moines
11h 05m
2 stops
SJC11:59 pmSan Jose
Dec 13
SJC6:10 amSan Jose
6h 04m
1 stop
DSM2:14 pmDes Moines
$262
Find similar
Delta
Dec 11
DSM2:15 pmDes Moines
10h 46m
1 stop
SJC11:01 pmSan Jose
Dec 13
SJC6:10 amSan Jose
6h 04m
1 stop
DSM2:14 pmDes Moines
$272
Find similar

American Airlines flights from Des Moines to San Jose

Our best American Airlines deals on Des Moines to San Jose flight tickets
American Airlines
Oct 2
DSM5:55 pmDes Moines
6h 52m
1 stop
SJC10:47 pmSan Jose
Oct 7
SJC6:00 amSan Jose
6h 58m
1 stop
DSM2:58 pmDes Moines
$287
Find similar
American Airlines
Oct 16
DSM5:30 amDes Moines
5h 51m
1 stop
SJC9:21 amSan Jose
Oct 22
SJC6:00 amSan Jose
7h 03m
1 stop
DSM3:03 pmDes Moines
$309
Find similar
American Airlines
Dec 9
DSM5:00 amDes Moines
7h 23m
1 stop
SJC10:23 amSan Jose
Dec 12
SJC3:30 pmSan Jose
6h 29m
1 stop
DSM11:59 pmDes Moines
$360
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to San Jose that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Des Moines to San Jose that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Tue 12/9

2:15 pm-11:01 pm

1 stop10h 46m

San Jose

Sat 12/13

6:10 am-2:14 pm

1 stop6h 04m

$257

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Tue 12/9

2:54 pm-11:59 pm

2 stops11h 05m

San Jose

Sat 12/13

6:10 am-2:14 pm

1 stop6h 04m

$262

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Thu 10/2

5:55 pm-10:47 pm

1 stop6h 52m

San Jose

Tue 10/7

6:00 am-2:58 pm

1 stop6h 58m

$287

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Sun 9/28

7:00 am-3:21 pm

2 stops34h 21m

San Jose

Thu 10/2

11:40 am-10:40 pm

1 stop9h 00m

$303

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Thu 10/16

5:30 am-9:21 am

1 stop5h 51m

San Jose

Wed 10/22

6:00 am-3:03 pm

1 stop7h 03m

$309

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Sun 9/28

3:42 pm-3:21 pm

1 stop25h 39m

San Jose

Thu 10/2

11:40 am-10:40 pm

1 stop9h 00m

$333

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Wed 11/26

1:05 pm-4:50 pm

1 stop5h 45m

San Jose

Mon 12/1

4:10 pm-11:10 pm

1 stop5h 00m

$477

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Wed 11/26

1:05 pm-4:50 pm

1 stop5h 45m

San Jose

Mon 12/1

6:30 am-11:10 pm

2 stops14h 40m

$498

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Thu 11/27

5:45 am-10:05 am

1 stop6h 20m

San Jose

Sat 11/29

6:30 am-1:42 am

1 stop17h 12m

$546

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Tue 11/25

5:45 am-10:05 am

1 stop6h 20m

San Jose

Sat 11/29

6:30 am-1:42 am

1 stop17h 12m

$596

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to San Jose from

How to get the cheapest flight ticket from Des Moines to San Jose

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Jose?

In general, November is the cheapest month to fly from Des Moines to San Jose. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $332. If you aren’t able to travel to San Jose during the month of November, then flying in October is also cheap. Prices for this month can be found on momondo for an average of $366.

What is the cheapest day to depart on your flight to San Jose?

The cheapest day to depart on your flight to San Jose is on a Friday when prices can be found for as low as $407. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Monday as prices are generally higher than usual. According to our data, the average ticket price to San Jose on Monday is $546.

What is the cheapest time of day to depart on your flight to San Jose?

Our most recent data shows that the best time of day to fly to San Jose is in the morning. Flights from Des Moines to San Jose during this time can be as low as $436. In contrast, the most expensive time of day to depart to San Jose is in the afternoon when prices are around $482.

When to book flights from Des Moines to San Jose

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to San Jose according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to San Jose (DSM to SJC) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to San Jose

Direct flights

None
There are no direct flights from Des Moines to San Jose. There are no popular flight routes from Des Moines to San Jose.
Search flight deals

  • When did momondo last update prices for flights from Des Moines Airport to San Jose Airport?

    Prices for flights from Des Moines Airport to San Jose Airport are updated daily.

  • How many operators does momondo search for flights from Des Moines Airport to San Jose Airport?

  • How old do you have to be to fly from Des Moines Airport to San Jose Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to San Jose Airport.

  • What documentation or ID do you need to fly to San Jose Airport?

    The travel and health documents you'll need for your trip to San Jose Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Jose Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to San Jose?

Best airlines flying from Des Moines to San Jose

Compare and see reviews for airlines that fly from Des Moines to San Jose with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $296Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $296Free CancellationRating
7.4
8,931 reviews
Search United Airlines flights
DeltaPriceFrom $302Free CancellationRating
7.9
7,956 reviews
Search Delta flights
SouthwestPriceFrom $367Free CancellationRating
8.0
4,245 reviews
Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to San Jose?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Des Moines to San Jose. momondo saves you time and could save you money on your trip.

Can I find flights from Des Moines to San Jose with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Jose from Des Moines with this policy.

How can momondo help me find flights from Des Moines to San Jose?

momondo provides multiple filters to help you find the best flight to San Jose from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to San Jose right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to San Jose flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your San Jose trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 10/15
Wed 10/22
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States