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Cheap flights from Des Moines to San Jose from $112

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to San Jose departing on 12/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

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American Airlines Logo
5:00 am - 10:23 amDSM-SJC
7h 23m1 stop
American Airlines Logo
3:30 pm - 11:59 pmSJC-DSM
6h 29m1 stop
$317American Airlines
Find Deal
Tue, Dec 9 - Tue, Dec 16
Delta Logo
4:21 pm - 9:28 pmDSM-SJC
7h 07m1 stop
Delta Logo
7:15 am - 9:24 pmSJC-DSM
12h 09m2 stops
$322Delta
Find Deal
Tue, Feb 3 - Tue, Feb 10
Delta Logo
12:06 pm - 11:58 pmDSM-SJC
13h 52m2 stops
Delta Logo
7:15 am - 9:24 pmSJC-DSM
12h 09m2 stops
$327Delta
Find Deal
Tue, Feb 3 - Tue, Feb 10
United Airlines Logo
9:03 am - 1:39 pmDSM-SJC
6h 36m1 stop
United Airlines Logo
4:00 pm - 11:44 pmSJC-DSM
5h 44m1 stop
$341United Airlines
Find Deal
Tue, Feb 3 - Tue, Feb 10
United Airlines Logo
11:30 am - 8:56 pmDSM-SJC
11h 26m2 stops
United Airlines Logo
4:00 pm - 11:44 pmSJC-DSM
5h 44m1 stop
$346United Airlines
Find Deal
Tue, Feb 3 - Tue, Feb 10
American Airlines Logo
5:21 am - 10:57 amDSM-SJC
7h 36m1 stop
American Airlines Logo
6:00 am - 5:06 pmSJC-DSM
9h 06m1 stop
$355American Airlines
Find Deal
Thu, Jan 15 - Tue, Jan 20
Delta Logo
10:54 am - 7:12 pmDSM-SJC
10h 18m2 stops
Delta Logo
10:30 pm - 10:41 amSJC-DSM
10h 11m1 stop
$360Delta
Find Deal
Thu, Jan 15 - Tue, Jan 20
Delta Logo
10:54 am - 9:56 pmDSM-SJC
13h 02m2 stops
Delta Logo
8:05 pm - 10:51 amSJC-DSM
12h 46m2 stops
$365Delta
Find Deal
Thu, Jan 15 - Tue, Jan 20
American Airlines Logo
4:00 pm - 10:15 pmDSM-SJC
8h 15m1 stop
American Airlines Logo
6:00 am - 5:06 pmSJC-DSM
9h 06m1 stop
$376American Airlines
Find Deal
Thu, Jan 15 - Sun, Jan 18
American Airlines Logo
4:00 pm - 10:49 pmDSM-SJC
8h 49m2 stops
American Airlines Logo
6:00 am - 5:06 pmSJC-DSM
9h 06m1 stop
$381American Airlines
Find Deal
Thu, Jan 15 - Sun, Jan 18

American Airlines flights from Des Moines to San Jose, California

Our best American Airlines deals on Des Moines to San Jose, California flight tickets
American Airlines
Dec 9
DSM5:00 amDes Moines
7h 23m
1 stop
SJC10:23 amSan Jose
Dec 16
SJC3:30 pmSan Jose
6h 29m
1 stop
DSM11:59 pmDes Moines
$317
Find similar
American Airlines
Jan 15
DSM5:21 amDes Moines
7h 36m
1 stop
SJC10:57 amSan Jose
Jan 20
SJC6:00 amSan Jose
9h 06m
1 stop
DSM5:06 pmDes Moines
$355
Find similar
American Airlines
Jan 15
DSM4:00 pmDes Moines
8h 15m
1 stop
SJC10:15 pmSan Jose
Jan 18
SJC6:00 amSan Jose
9h 06m
1 stop
DSM5:06 pmDes Moines
$376
Find similar

Delta flights from Des Moines to San Jose, California

Our best Delta deals on Des Moines to San Jose, California flight tickets
Delta
Feb 3
DSM4:21 pmDes Moines
7h 07m
1 stop
SJC9:28 pmSan Jose
Feb 10
SJC7:15 amSan Jose
12h 09m
2 stops
DSM9:24 pmDes Moines
$322
Find similar
Delta
Feb 3
DSM12:06 pmDes Moines
13h 52m
2 stops
SJC11:58 pmSan Jose
Feb 10
SJC7:15 amSan Jose
12h 09m
2 stops
DSM9:24 pmDes Moines
$327
Find similar
Delta
Jan 15
DSM10:54 amDes Moines
10h 18m
2 stops
SJC7:12 pmSan Jose
Jan 20
SJC10:30 pmSan Jose
10h 11m
1 stop
DSM10:41 amDes Moines
$360
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to San Jose, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Des Moines to San Jose, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Tue 12/9

5:00 am-10:23 am

1 stop7h 23m

San Jose

Tue 12/16

3:30 pm-11:59 pm

1 stop6h 29m

$317

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Tue 2/3

4:21 pm-9:28 pm

1 stop7h 07m

San Jose

Tue 2/10

7:15 am-9:24 pm

2 stops12h 09m

$322

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Tue 2/3

12:06 pm-11:58 pm

2 stops13h 52m

San Jose

Tue 2/10

7:15 am-9:24 pm

2 stops12h 09m

$327

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Tue 2/3

9:03 am-1:39 pm

1 stop6h 36m

San Jose

Tue 2/10

4:00 pm-11:44 pm

1 stop5h 44m

$341

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Tue 2/3

11:30 am-8:56 pm

2 stops11h 26m

San Jose

Tue 2/10

4:00 pm-11:44 pm

1 stop5h 44m

$346

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Thu 1/15

5:21 am-10:57 am

1 stop7h 36m

San Jose

Tue 1/20

6:00 am-5:06 pm

1 stop9h 06m

$355

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Thu 1/15

10:54 am-7:12 pm

2 stops10h 18m

San Jose

Tue 1/20

10:30 pm-10:41 am

1 stop10h 11m

$360

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Thu 1/15

10:54 am-9:56 pm

2 stops13h 02m

San Jose

Tue 1/20

8:05 pm-10:51 am

2 stops12h 46m

$365

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Thu 1/15

4:00 pm-10:15 pm

1 stop8h 15m

San Jose

Sun 1/18

6:00 am-5:06 pm

1 stop9h 06m

$376

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Thu 1/15

4:00 pm-10:49 pm

2 stops8h 49m

San Jose

Sun 1/18

6:00 am-5:06 pm

1 stop9h 06m

$381

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Des Moines to San Jose, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Jose, California?

The month of April is, on average, the cheapest month to fly to San Jose, California from Des Moines, with most prices found around $356. If you are unable to visit San Jose, California during the month of April, then departing from Des Moines during the month August is also very affordable. Most momondo users find prices during this month for around $367.

What is the cheapest day to depart on your flight to San Jose, California?

On average, the least expensive day to fly to San Jose, California from Des Moines is on a Friday. momondo users have found tickets for Friday departures for as low as $407. However, this price may fluctuate depending on the airline, the season, and holidays. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from Des Moines to San Jose, California for around $546.

What is the cheapest time of day to depart on your flight to San Jose, California?

The cheapest time of day to fly to San Jose, California is in the morning when flights can be purchased for as low as $436. In the afternoon is when there is more demand to fly to San Jose, California, so prices are often more expensive at around $482 per ticket.

When to book flights from Des Moines to San Jose, California

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to San Jose, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to San Jose, California (DSM to SJC) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to San Jose, California

Direct flights

None
There are no direct flights from Des Moines to San Jose, California. There are no popular flight routes from Des Moines to San Jose, California.
Search flight deals

  • How far is Des Moines to San Jose by plane?

    The straight-line distance from Des Moines to San Jose is 1527.5 mi. 5h 45m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to San Jose Airport?

    Prices for flights from Des Moines Airport to San Jose Airport are updated daily.

  • How many operators does momondo search for flights from Des Moines Airport to San Jose Airport?

  • How old do you have to be to fly from Des Moines Airport to San Jose Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to San Jose Airport.

  • What documentation or ID do you need to fly to San Jose Airport?

    The travel and health documents you'll need for your trip to San Jose Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Jose Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to San Jose, California?

Best airlines flying from Des Moines to San Jose, California

Compare and see reviews for airlines that fly from Des Moines to San Jose, California with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $296Free CancellationRating
7.2
11,051 reviews
Search American Airlines flights
United AirlinesPriceFrom $296Free CancellationRating
7.4
9,017 reviews
Search United Airlines flights
DeltaPriceFrom $302Free CancellationRating
7.9
8,007 reviews
Search Delta flights
SouthwestPriceFrom $367Free CancellationRating
8.0
4,242 reviews
Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to San Jose?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Des Moines to San Jose. momondo saves you time and could save you money on your trip.

Can I find flights from Des Moines to San Jose with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Jose from Des Moines with this policy.

How can momondo help me find flights from Des Moines to San Jose?

momondo provides multiple filters to help you find the best flight to San Jose from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to San Jose right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to San Jose flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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