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Cheap flights from Des Moines to San Jose from $204

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to San Jose departing on 1/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Des Moines to San Jose

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
3:30 pm - 8:35 pmDSM-SJC
7h 05m1 stop
Delta Logo
6:15 am - 2:08 pmSJC-DSM
5h 53m1 stop
$285Delta
Find Deal
Mon, Nov 24 - Thu, Nov 27
Delta Logo
3:30 pm - 8:35 pmDSM-SJC
7h 05m1 stop
Delta Logo
7:45 pm - 10:20 amSJC-DSM
12h 35m2 stops
$290Delta
Find Deal
Mon, Nov 24 - Thu, Nov 27
Delta Logo
11:00 am - 6:19 pmDSM-SJC
9h 19m2 stops
Delta Logo
7:45 pm - 10:20 amSJC-DSM
12h 35m2 stops
$295Delta
Find Deal
Mon, Nov 24 - Thu, Nov 27
Southwest Logo
6:25 am - 9:50 amDSM-SJC
5h 25m1 stop
Southwest Logo
12:25 pm - 7:55 pmSJC-DSM
5h 30m1 stop
$301Southwest
Find Deal
Fri, Oct 31 - Tue, Nov 4
Delta Logo
3:30 pm - 9:31 pmDSM-SJC
8h 01m2 stops
Delta Logo
1:20 pm - 9:03 pmSJC-DSM
5h 43m1 stop
$306Delta
Find Deal
Fri, Oct 31 - Tue, Nov 4
Delta Logo
11:06 am - 9:31 pmDSM-SJC
12h 25m2 stops
Delta Logo
8:10 pm - 10:26 amSJC-DSM
12h 16m2 stops
$311Delta
Find Deal
Fri, Oct 31 - Tue, Nov 4
American Airlines Logo
6:17 pm - 10:49 pmDSM-SJC
6h 32m1 stop
American Airlines Logo
6:00 am - 1:38 pmSJC-DSM
5h 38m1 stop
$322American Airlines
Find Deal
Thu, Jan 15 - Sun, Jan 18
American Airlines Logo
6:17 pm - 10:49 pmDSM-SJC
6h 32m1 stop
American Airlines Logo
6:00 am - 5:06 pmSJC-DSM
9h 06m2 stops
$327American Airlines
Find Deal
Thu, Jan 15 - Tue, Jan 20
United Airlines Logo
3:15 pm - 10:28 pmDSM-SJC
9h 13m1 stop
United Airlines Logo
4:00 pm - 11:44 pmSJC-DSM
5h 44m1 stop
$442United Airlines
Find Deal
Wed, Nov 26 - Wed, Dec 3
United Airlines Logo
8:02 am - 3:33 pmDSM-SJC
9h 31m1 stop
United Airlines Logo
8:45 am - 9:37 pmSJC-DSM
10h 52m2 stops
$454United Airlines
Find Deal
Thu, Nov 27 - Thu, Dec 4

Delta flights from Des Moines to San Jose, California

Our best Delta deals on Des Moines to San Jose, California flight tickets
Delta
Nov 24
DSM3:30 pmDes Moines
7h 05m
1 stop
SJC8:35 pmSan Jose
Nov 27
SJC6:15 amSan Jose
5h 53m
1 stop
DSM2:08 pmDes Moines
$285
Find similar
Delta
Nov 24
DSM3:30 pmDes Moines
7h 05m
1 stop
SJC8:35 pmSan Jose
Nov 27
SJC7:45 pmSan Jose
12h 35m
2 stops
DSM10:20 amDes Moines
$290
Find similar
Delta
Nov 24
DSM11:00 amDes Moines
9h 19m
2 stops
SJC6:19 pmSan Jose
Nov 27
SJC7:45 pmSan Jose
12h 35m
2 stops
DSM10:20 amDes Moines
$295
Find similar

American Airlines flights from Des Moines to San Jose, California

Our best American Airlines deals on Des Moines to San Jose, California flight tickets
American Airlines
Jan 15
DSM6:17 pmDes Moines
6h 32m
1 stop
SJC10:49 pmSan Jose
Jan 18
SJC6:00 amSan Jose
5h 38m
1 stop
DSM1:38 pmDes Moines
$322
Find similar
American Airlines
Jan 15
DSM6:17 pmDes Moines
6h 32m
1 stop
SJC10:49 pmSan Jose
Jan 20
SJC6:00 amSan Jose
9h 06m
2 stops
DSM5:06 pmDes Moines
$327
Find similar
American Airlines
Jan 22
DSM5:21 amDes Moines
7h 36m
1 stop
SJC10:57 amSan Jose
Jan 27
SJC2:37 pmSan Jose
6h 46m
1 stop
DSM11:23 pmDes Moines
$338
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to San Jose, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 14, 2025.
Use the filters below to find and compare flights from Des Moines to San Jose, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Mon 11/24

3:30 pm-8:35 pm

1 stop7h 05m

San Jose

Thu 11/27

6:15 am-2:08 pm

1 stop5h 53m

$285

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Mon 11/24

3:30 pm-8:35 pm

1 stop7h 05m

San Jose

Thu 11/27

7:45 pm-10:20 am

2 stops12h 35m

$290

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Mon 11/24

11:00 am-6:19 pm

2 stops9h 19m

San Jose

Thu 11/27

7:45 pm-10:20 am

2 stops12h 35m

$295

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Fri 10/31

6:25 am-9:50 am

1 stop5h 25m

San Jose

Tue 11/4

12:25 pm-7:55 pm

1 stop5h 30m

$301

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Fri 10/31

3:30 pm-9:31 pm

2 stops8h 01m

San Jose

Tue 11/4

1:20 pm-9:03 pm

1 stop5h 43m

$306

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Fri 10/31

11:06 am-9:31 pm

2 stops12h 25m

San Jose

Tue 11/4

8:10 pm-10:26 am

2 stops12h 16m

$311

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Thu 1/15

6:17 pm-10:49 pm

1 stop6h 32m

San Jose

Sun 1/18

6:00 am-1:38 pm

1 stop5h 38m

$322

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Thu 1/15

6:17 pm-10:49 pm

1 stop6h 32m

San Jose

Tue 1/20

6:00 am-5:06 pm

2 stops9h 06m

$327

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Wed 11/26

3:15 pm-10:28 pm

1 stop9h 13m

San Jose

Wed 12/3

4:00 pm-11:44 pm

1 stop5h 44m

$442

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Thu 11/27

8:02 am-3:33 pm

1 stop9h 31m

San Jose

Thu 12/4

8:45 am-9:37 pm

2 stops10h 52m

$454

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
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See travel insights to San Jose from

How to get the cheapest flight ticket from Des Moines to San Jose, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Jose, California?

The month of August is, on average, the cheapest month to fly to San Jose, California from Des Moines, with most prices found around $367. If you are unable to visit San Jose, California during the month of August, then departing from Des Moines during the month April is also very affordable. Most momondo users find prices during this month for around $374.

What is the cheapest day to depart on your flight to San Jose, California?

On average, the least expensive day to fly to San Jose, California from Des Moines is on a Friday. momondo users have found tickets for Friday departures for as low as $407. However, this price may fluctuate depending on the airline, the season, and holidays. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from Des Moines to San Jose, California for around $546.

What is the cheapest time of day to depart on your flight to San Jose, California?

The cheapest time of day to fly to San Jose, California is in the morning when flights can be purchased for as low as $436. In the afternoon is when there is more demand to fly to San Jose, California, so prices are often more expensive at around $482 per ticket.

When to book flights from Des Moines to San Jose, California

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to San Jose, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to San Jose, California (DSM to SJC) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to San Jose, California

Direct flights

None
There are no direct flights from Des Moines to San Jose, California. There are no popular flight routes from Des Moines to San Jose, California.
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  • How far is Des Moines to San Jose by plane?

    The straight-line distance from Des Moines to San Jose is 1527.5 mi. 5h 25m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to San Jose Airport?

    Prices for flights from Des Moines Airport to San Jose Airport are updated daily.

  • How many operators does momondo search for flights from Des Moines Airport to San Jose Airport?

  • How old do you have to be to fly from Des Moines Airport to San Jose Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to San Jose Airport.

  • What documentation or ID do you need to fly to San Jose Airport?

    The travel and health documents you'll need for your trip to San Jose Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Jose Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to San Jose, California?

Best airlines flying from Des Moines to San Jose, California

Compare and see reviews for airlines that fly from Des Moines to San Jose, California with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $296Free CancellationRating
7.2
11,042 reviews
Search American Airlines flights
United AirlinesPriceFrom $296Free CancellationRating
7.4
8,976 reviews
Search United Airlines flights
DeltaPriceFrom $302Free CancellationRating
7.9
7,975 reviews
Search Delta flights
SouthwestPriceFrom $367Free CancellationRating
8.0
4,238 reviews
Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to San Jose?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Des Moines to San Jose. momondo saves you time and could save you money on your trip.

Can I find flights from Des Moines to San Jose with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Jose from Des Moines with this policy.

How can momondo help me find flights from Des Moines to San Jose?

momondo provides multiple filters to help you find the best flight to San Jose from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to San Jose right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to San Jose flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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