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Cheap flights from Des Moines to San Jose from $197

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to San Jose departing on 3/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Des Moines to San Jose

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
11:49 am - 7:02 pm
DSM
-
SJC
9h 13m
1 stop
Delta Logo
6:15 am - 5:06 pm
SJC
-
DSM
8h 51m
1 stop
$317Delta
Wed, May 13 - Tue, May 19
Delta Logo
10:56 am - 10:14 pm
DSM
-
SJC
13h 18m
2 stops
Delta Logo
6:15 am - 5:06 pm
SJC
-
DSM
8h 51m
1 stop
$322Delta
Wed, May 13 - Wed, May 20
Delta Logo
10:56 am - 10:14 pm
DSM
-
SJC
13h 18m
2 stops
Delta Logo
7:00 am - 8:58 pm
SJC
-
DSM
11h 58m
2 stops
$327Delta
Wed, May 13 - Wed, May 20
Delta Logo
4:23 pm - 8:37 pm
DSM
-
SJC
6h 14m
1 stop
Delta Logo
8:05 pm - 10:18 am
SJC
-
DSM
12h 13m
2 stops
$332Delta
Wed, Apr 15 - Tue, Apr 21
Delta Logo
2:33 pm - 10:55 pm
DSM
-
SJC
10h 22m
1 stop
Delta Logo
1:13 pm - 8:58 pm
SJC
-
DSM
5h 45m
1 stop
$352Delta
Wed, May 20 - Tue, May 26
Delta Logo
5:35 am - 12:08 pm
DSM
-
SJC
8h 33m
1 stop
Delta Logo
6:20 am - 3:42 pm
SJC
-
DSM
7h 22m
1 stop
$355Delta
Sat, Mar 28 - Wed, Apr 1
Delta Logo
2:33 pm - 10:55 pm
DSM
-
SJC
10h 22m
1 stop
Delta Logo
7:00 am - 8:58 pm
SJC
-
DSM
11h 58m
2 stops
$357Delta
Wed, May 20 - Tue, May 26
Delta Logo
2:39 pm - 8:38 pm
DSM
-
SJC
7h 59m
1 stop
Delta Logo
6:11 pm - 10:16 am
SJC
-
DSM
14h 05m
2 stops
$359Delta
Wed, May 13 - Mon, May 18
Delta Logo
4:25 pm - 11:58 pm
DSM
-
SJC
9h 33m
2 stops
Delta Logo
6:20 am - 3:42 pm
SJC
-
DSM
7h 22m
1 stop
$360Delta
Mon, Mar 30 - Tue, Apr 7
Delta Logo
2:33 pm - 10:55 pm
DSM
-
SJC
10h 22m
1 stop
Delta Logo
7:59 pm - 10:16 am
SJC
-
DSM
12h 17m
2 stops
$362Delta
Wed, May 20 - Tue, May 26

Delta flights from Des Moines to San Jose, California

Our best Delta deals on Des Moines to San Jose, California flight tickets
Delta
May 13
DSM11:49 amDes Moines
9h 13m
1 stop
SJC7:02 pmSan Jose
May 19
SJC6:15 amSan Jose
8h 51m
1 stop
DSM5:06 pmDes Moines
$317
Delta
May 13
DSM10:56 amDes Moines
13h 18m
2 stops
SJC10:14 pmSan Jose
May 20
SJC6:15 amSan Jose
8h 51m
1 stop
DSM5:06 pmDes Moines
$322
Delta
May 13
DSM10:56 amDes Moines
13h 18m
2 stops
SJC10:14 pmSan Jose
May 20
SJC7:00 amSan Jose
11h 58m
2 stops
DSM8:58 pmDes Moines
$327

Southwest flights from Des Moines to San Jose, California

Our best Southwest deals on Des Moines to San Jose, California flight tickets
Southwest
Apr 10
DSM1:55 pmDes Moines
8h 35m
2 stops
SJC8:30 pmSan Jose
Apr 14
SJC11:15 amSan Jose
8h 00m
2 stops
DSM9:15 pmDes Moines
$417
Southwest
Apr 2
DSM6:50 amDes Moines
5h 30m
1 stop
SJC10:20 amSan Jose
Apr 5
SJC10:55 pmSan Jose
11h 15m
1 stop
DSM12:10 pmDes Moines
$425
Southwest
Apr 2
DSM6:50 amDes Moines
8h 40m
2 stops
SJC1:30 pmSan Jose
Apr 5
SJC10:55 pmSan Jose
11h 15m
1 stop
DSM12:10 pmDes Moines
$431

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to San Jose, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 13, 2026.
Use the filters below to find and compare flights from Des Moines to San Jose, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Wed 5/13

11:49 am-7:02 pm

1 stop9h 13m

San Jose

Tue 5/19

6:15 am-5:06 pm

1 stop8h 51m

$317

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Wed 5/13

10:56 am-10:14 pm

2 stops13h 18m

San Jose

Wed 5/20

6:15 am-5:06 pm

1 stop8h 51m

$322

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Wed 5/13

10:56 am-10:14 pm

2 stops13h 18m

San Jose

Wed 5/20

7:00 am-8:58 pm

2 stops11h 58m

$327

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Wed 4/15

4:23 pm-8:37 pm

1 stop6h 14m

San Jose

Tue 4/21

8:05 pm-10:18 am

2 stops12h 13m

$332

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Wed 5/20

2:33 pm-10:55 pm

1 stop10h 22m

San Jose

Tue 5/26

1:13 pm-8:58 pm

1 stop5h 45m

$352

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Sat 3/28

5:35 am-12:08 pm

1 stop8h 33m

San Jose

Wed 4/1

6:20 am-3:42 pm

1 stop7h 22m

$355

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Wed 5/20

2:33 pm-10:55 pm

1 stop10h 22m

San Jose

Tue 5/26

7:00 am-8:58 pm

2 stops11h 58m

$357

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Wed 5/13

2:39 pm-8:38 pm

1 stop7h 59m

San Jose

Mon 5/18

6:11 pm-10:16 am

2 stops14h 05m

$359

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Mon 3/30

4:25 pm-11:58 pm

2 stops9h 33m

San Jose

Tue 4/7

6:20 am-3:42 pm

1 stop7h 22m

$360

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Wed 5/20

2:33 pm-10:55 pm

1 stop10h 22m

San Jose

Tue 5/26

7:59 pm-10:16 am

2 stops12h 17m

$362

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Jose from

How to get the cheapest flight ticket from Des Moines to San Jose, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Jose, California?

The month of April is, on average, the cheapest month to fly to San Jose, California from Des Moines, with most prices found around $356. If you are unable to visit San Jose, California during the month of April, then departing from Des Moines during the month August is also very affordable. Most momondo users find prices during this month for around $367.

When to book flights from Des Moines to San Jose, California

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to San Jose, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to San Jose, California (DSM to SJC) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to San Jose, California

Fastest flight time

5h 30m

Direct flights

None
The fastest flight from Des Moines to San Jose, California takes 5h 30m
There are no direct flights from Des Moines to San Jose, California. There are no popular flight routes from Des Moines to San Jose, California.
Search flight deals

  • How far is Des Moines to San Jose by plane?

    The straight-line distance from Des Moines to San Jose is 1527.5 mi. 5h 30m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to San Jose Airport?

    Prices for flights from Des Moines Airport to San Jose Airport are updated daily.

  • How many operators does momondo search for flights from Des Moines Airport to San Jose Airport?

  • How old do you have to be to fly from Des Moines Airport to San Jose Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to San Jose Airport.

  • What documentation or ID do you need to fly to San Jose Airport?

    The travel and health documents you'll need for your trip to San Jose Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Jose Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to San Jose, California?

Best airlines flying from Des Moines to San Jose, California

Compare and see reviews for airlines that fly from Des Moines to San Jose, California with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $179Free CancellationRating
7.9
8,191 reviews
Search Delta flights
American AirlinesPriceFrom $290Free CancellationRating
7.2
11,277 reviews
Search American Airlines flights
United AirlinesPriceFrom $296Free CancellationRating
7.4
9,286 reviews
Search United Airlines flights
SouthwestPriceFrom $356Free CancellationRating
8.0
4,283 reviews
Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to San Jose?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Des Moines to San Jose. momondo saves you time and could save you money on your trip.

Can I find flights from Des Moines to San Jose with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Jose from Des Moines with this policy.

How can momondo help me find flights from Des Moines to San Jose?

momondo provides multiple filters to help you find the best flight to San Jose from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to San Jose right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to San Jose flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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