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Cheap flights from Des Moines to San Jose from $185

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to San Jose departing on 9/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to San Jose

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
11:29 am - 7:53 pm
DSM
-
SJC
34h 24m
2 stops
Multiple Airlines Logo
1:38 pm - 8:41 pm
SJC
-
DSM
29h 03m
1 stop
$316Multiple Airlines
Sun, Sep 13 - Sun, Sep 20
Multiple Airlines Logo
11:29 am - 7:53 pm
DSM
-
SJC
34h 24m
2 stops
Multiple Airlines Logo
1:38 pm - 8:41 pm
SJC
-
DSM
29h 03m
1 stop
$320Multiple Airlines
Sun, Sep 13 - Sun, Sep 20
Multiple Airlines Logo
9:50 pm - 1:22 pm
DSM
-
SJC
17h 32m
1 stop
Multiple Airlines Logo
1:02 pm - 11:10 am
SJC
-
DSM
20h 08m
1 stop
$363Multiple Airlines
Thu, Aug 27 - Thu, Sep 3
Southwest Logo
4:50 pm - 9:20 pm
DSM
-
SJC
6h 30m
1 stop
Southwest Logo
6:15 am - 4:10 pm
SJC
-
DSM
7h 55m
1 stop
$369Southwest
Sat, Sep 12 - Sat, Sep 19
United Airlines Logo
5:21 pm - 8:54 pm
DSM
-
SJC
5h 33m
1 stop
United Airlines Logo
8:45 am - 4:19 pm
SJC
-
DSM
5h 34m
1 stop
$369United Airlines
Sat, Sep 12 - Sat, Sep 19
American Airlines Logo
5:30 am - 11:57 am
DSM
-
SJC
8h 27m
1 stop
American Airlines Logo
4:00 pm - 11:59 pm
SJC
-
DSM
5h 59m
1 stop
$369American Airlines
Tue, Sep 1 - Sat, Sep 12
American Airlines Logo
5:06 am - 12:08 pm
DSM
-
SJC
9h 02m
1 stop
American Airlines Logo
12:58 pm - 11:40 pm
SJC
-
DSM
8h 42m
1 stop
$369American Airlines
Thu, Oct 15 - Thu, Oct 22
American Airlines Logo
5:30 am - 11:57 am
DSM
-
SJC
8h 27m
1 stop
American Airlines Logo
12:03 pm - 11:25 pm
SJC
-
DSM
9h 22m
1 stop
$369American Airlines
Thu, Aug 20 - Wed, Aug 26
United Airlines Logo
9:13 am - 1:08 pm
DSM
-
SJC
5h 55m
1 stop
United Airlines Logo
2:10 pm - 10:55 pm
SJC
-
DSM
6h 45m
1 stop
$373United Airlines
Wed, Sep 9 - Sat, Sep 12
Southwest Logo
7:10 pm - 10:30 pm
DSM
-
SJC
5h 20m
1 stop
Southwest Logo
11:00 pm - 11:30 am
SJC
-
DSM
10h 30m
1 stop
$374Southwest
Thu, Oct 8 - Mon, Oct 12

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Delta flights from Des Moines to San Jose, California

Our best Delta deals on Des Moines to San Jose, California flight tickets
Delta
Sep 1
DSM5:40 amDes Moines
7h 42m
1 stop
SJC11:22 amSan Jose
Sep 12
SJC7:00 amSan Jose
12h 11m
2 stops
DSM9:11 pmDes Moines
$374
Delta
Sep 1
DSM6:55 amDes Moines
9h 19m
2 stops
SJC2:14 pmSan Jose
Sep 12
SJC7:00 amSan Jose
12h 11m
2 stops
DSM9:11 pmDes Moines
$380
Delta
Sep 1
DSM5:40 amDes Moines
7h 42m
1 stop
SJC11:22 amSan Jose
Sep 12
SJC7:00 amSan Jose
12h 11m
2 stops
DSM9:11 pmDes Moines
$386

Southwest flights from Des Moines to San Jose, California

Our best Southwest deals on Des Moines to San Jose, California flight tickets
Southwest
Sep 9
DSM7:15 amDes Moines
7h 50m
2 stops
SJC1:05 pmSan Jose
Sep 12
SJC6:15 amSan Jose
7h 55m
1 stop
DSM4:10 pmDes Moines
$378
Southwest
Sep 12
DSM7:20 amDes Moines
9h 25m
2 stops
SJC2:45 pmSan Jose
Sep 19
SJC10:45 amSan Jose
8h 05m
2 stops
DSM8:50 pmDes Moines
$379
Southwest
Sep 9
DSM12:30 pmDes Moines
8h 45m
2 stops
SJC7:15 pmSan Jose
Sep 12
SJC6:30 amSan Jose
7h 40m
2 stops
DSM4:10 pmDes Moines
$383

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to San Jose, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 2, 2026.
Use the filters below to find and compare flights from Des Moines to San Jose, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Sun 9/13

11:29 am-7:53 pm

2 stops34h 24m

San Jose

Sun 9/20

1:38 pm-8:41 pm

1 stop29h 03m

$316

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Sun 9/13

11:29 am-7:53 pm

2 stops34h 24m

San Jose

Sun 9/20

1:38 pm-8:41 pm

1 stop29h 03m

$320

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Thu 8/27

9:50 pm-1:22 pm

1 stop17h 32m

San Jose

Thu 9/3

1:02 pm-11:10 am

1 stop20h 08m

$363

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Sat 9/12

4:50 pm-9:20 pm

1 stop6h 30m

San Jose

Sat 9/19

6:15 am-4:10 pm

1 stop7h 55m

$369
Quickest round-trip

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Sat 9/12

5:21 pm-8:54 pm

1 stop5h 33m

San Jose

Sat 9/19

8:45 am-4:19 pm

1 stop5h 34m

$369

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Tue 9/1

5:30 am-11:57 am

1 stop8h 27m

San Jose

Sat 9/12

4:00 pm-11:59 pm

1 stop5h 59m

$369

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Thu 10/15

5:06 am-12:08 pm

1 stop9h 02m

San Jose

Thu 10/22

12:58 pm-11:40 pm

1 stop8h 42m

$369

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Thu 8/20

5:30 am-11:57 am

1 stop8h 27m

San Jose

Wed 8/26

12:03 pm-11:25 pm

1 stop9h 22m

$369

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Wed 9/9

9:13 am-1:08 pm

1 stop5h 55m

San Jose

Sat 9/12

2:10 pm-10:55 pm

1 stop6h 45m

$373

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Thu 10/8

7:10 pm-10:30 pm

1 stop5h 20m

San Jose

Mon 10/12

11:00 pm-11:30 am

1 stop10h 30m

$374

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Jose from

How to get the cheapest flight ticket from Des Moines to San Jose, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Des Moines and San Jose, California?

Prices are currently low for flights on this route.

Typical prices usually range from $465 to $518.
The lowest price recently found on this route was $316.

What is the cheapest month to fly to San Jose, California?

The month of February is, on average, the cheapest month to fly to San Jose, California from Des Moines, with most prices found around $367. If you are unable to visit San Jose, California during the month of February, then departing from Des Moines during the month December is also very affordable. Most momondo users find prices during this month for around $392.

When to book flights from Des Moines to San Jose, California

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to San Jose, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to San Jose, California (DSM to SJC) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to San Jose, California

Fastest flight time

5h 26m

Direct flights

None
The fastest flight from Des Moines to San Jose, California takes 5h 26m
There are no direct flights from Des Moines to San Jose, California. There are no popular flight routes from Des Moines to San Jose, California.
Search flight deals

Frequently asked questions about flying from Des Moines to San Jose, California

  • How far is Des Moines to San Jose by plane?

    The straight-line distance from Des Moines to San Jose is 1527.5 mi. 5h 26m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to San Jose Airport?

    Prices for flights from Des Moines Airport to San Jose Airport are updated daily.

  • How many operators does momondo search for flights from Des Moines Airport to San Jose Airport?

  • How old do you have to be to fly from Des Moines Airport to San Jose Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to San Jose Airport.

  • What documentation or ID do you need to fly to San Jose Airport?

    The travel and health documents you'll need for your trip to San Jose Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Jose Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to San Jose, California?

Best airlines flying from Des Moines to San Jose, California

Compare and see reviews for airlines that fly from Des Moines to San Jose, California with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $332Free CancellationRating
7.1
11,845 reviews
Search American Airlines flights
United AirlinesPriceFrom $361Free CancellationRating
7.4
10,062 reviews
Search United Airlines flights
SouthwestPriceFrom $379Free CancellationRating
8.0
4,229 reviews
Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to San Jose?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Des Moines to San Jose. momondo saves you time and could save you money on your trip.

Can I find flights from Des Moines to San Jose with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Jose from Des Moines with this policy.

How can momondo help me find flights from Des Moines to San Jose?

momondo provides multiple filters to help you find the best flight to San Jose from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to San Jose right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to San Jose flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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