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Cheap flights from Des Moines to San Jose from $132

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to San Jose departing on 8/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to San Jose

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
4:20 pm - 8:24 pm
DSM
-
SJC
6h 04m
1 stop
Delta Logo
6:30 am - 2:07 pm
SJC
-
DSM
5h 37m
1 stop
$291Delta
Tue, Sep 1 - Sat, Sep 12
Southwest Logo
6:40 pm - 10:15 pm
DSM
-
SJC
5h 35m
1 stop
Southwest Logo
8:30 am - 4:10 pm
SJC
-
DSM
5h 40m
1 stop
$292Southwest
Wed, Aug 5 - Sat, Aug 8
Delta Logo
5:40 am - 4:06 pm
DSM
-
SJC
12h 26m
2 stops
Delta Logo
6:30 am - 2:07 pm
SJC
-
DSM
5h 37m
1 stop
$296Delta
Tue, Sep 1 - Sat, Sep 12
Delta Logo
6:55 am - 3:50 pm
DSM
-
SJC
10h 55m
2 stops
Delta Logo
8:25 pm - 10:15 am
SJC
-
DSM
11h 50m
2 stops
$301Delta
Tue, Sep 1 - Sat, Sep 12
American Airlines Logo
4:13 pm - 10:32 pm
DSM
-
SJC
8h 19m
1 stop
American Airlines Logo
6:00 am - 5:52 pm
SJC
-
DSM
9h 52m
2 stops
$311American Airlines
Tue, Sep 1 - Sat, Sep 12
Southwest Logo
3:50 pm - 11:20 pm
DSM
-
SJC
9h 30m
1 stop
Southwest Logo
8:40 am - 5:45 pm
SJC
-
DSM
7h 05m
1 stop
$314Southwest
Thu, Sep 3 - Tue, Sep 8
Delta Logo
2:35 pm - 8:53 pm
DSM
-
SJC
8h 18m
1 stop
Delta Logo
6:10 am - 2:01 pm
SJC
-
DSM
5h 51m
1 stop
$318Delta
Fri, Sep 11 - Wed, Sep 16
Southwest Logo
7:00 pm - 10:25 pm
DSM
-
SJC
5h 25m
1 stop
Southwest Logo
11:00 pm - 11:50 am
SJC
-
DSM
10h 50m
1 stop
$319Southwest
Wed, Jul 22 - Tue, Aug 4
Delta Logo
5:40 am - 4:06 pm
DSM
-
SJC
12h 26m
2 stops
Delta Logo
9:05 am - 9:17 pm
SJC
-
DSM
10h 12m
2 stops
$323Delta
Tue, Sep 1 - Sat, Sep 12
Delta Logo
5:40 am - 11:28 am
DSM
-
SJC
7h 48m
1 stop
Delta Logo
8:53 pm - 10:18 am
SJC
-
DSM
11h 25m
2 stops
$324Delta
Sat, Aug 22 - Mon, Aug 31

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American Airlines flights from Des Moines to San Jose, California

Our best American Airlines deals on Des Moines to San Jose, California flight tickets
American Airlines
Sep 1
DSM4:13 pmDes Moines
8h 19m
1 stop
SJC10:32 pmSan Jose
Sep 12
SJC6:00 amSan Jose
9h 52m
2 stops
DSM5:52 pmDes Moines
$311
American Airlines
Aug 28
DSM2:39 pmDes Moines
5h 51m
1 stop
SJC6:30 pmSan Jose
Aug 31
SJC12:42 pmSan Jose
6h 04m
1 stop
DSM8:46 pmDes Moines
$346
American Airlines
Jul 14
DSM7:04 amDes Moines
10h 31m
2 stops
SJC3:35 pmSan Jose
Jul 21
SJC6:01 amSan Jose
10h 32m
2 stops
DSM6:33 pmDes Moines
$407

Delta flights from Des Moines to San Jose, California

Our best Delta deals on Des Moines to San Jose, California flight tickets
Delta
Sep 1
DSM4:20 pmDes Moines
6h 04m
1 stop
SJC8:24 pmSan Jose
Sep 12
SJC6:30 amSan Jose
5h 37m
1 stop
DSM2:07 pmDes Moines
$291
Delta
Sep 1
DSM4:20 pmDes Moines
6h 04m
1 stop
SJC8:24 pmSan Jose
Sep 12
SJC8:25 pmSan Jose
11h 50m
2 stops
DSM10:15 amDes Moines
$296
Delta
Sep 1
DSM6:55 amDes Moines
10h 55m
2 stops
SJC3:50 pmSan Jose
Sep 12
SJC8:25 pmSan Jose
11h 50m
2 stops
DSM10:15 amDes Moines
$301

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to San Jose, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 13, 2026.
Use the filters below to find and compare flights from Des Moines to San Jose, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Tue 9/1

4:20 pm-8:24 pm

1 stop6h 04m

San Jose

Sat 9/12

6:30 am-2:07 pm

1 stop5h 37m

$291
Quickest round-trip

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Wed 8/5

6:40 pm-10:15 pm

1 stop5h 35m

San Jose

Sat 8/8

8:30 am-4:10 pm

1 stop5h 40m

$292

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Tue 9/1

5:40 am-4:06 pm

2 stops12h 26m

San Jose

Sat 9/12

6:30 am-2:07 pm

1 stop5h 37m

$296

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Tue 9/1

6:55 am-3:50 pm

2 stops10h 55m

San Jose

Sat 9/12

8:25 pm-10:15 am

2 stops11h 50m

$301

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Tue 9/1

4:13 pm-10:32 pm

1 stop8h 19m

San Jose

Sat 9/12

6:00 am-5:52 pm

2 stops9h 52m

$311

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Thu 9/3

3:50 pm-11:20 pm

1 stop9h 30m

San Jose

Tue 9/8

8:40 am-5:45 pm

1 stop7h 05m

$314

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Fri 9/11

2:35 pm-8:53 pm

1 stop8h 18m

San Jose

Wed 9/16

6:10 am-2:01 pm

1 stop5h 51m

$318

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Wed 7/22

7:00 pm-10:25 pm

1 stop5h 25m

San Jose

Tue 8/4

11:00 pm-11:50 am

1 stop10h 50m

$319

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Tue 9/1

5:40 am-4:06 pm

2 stops12h 26m

San Jose

Sat 9/12

9:05 am-9:17 pm

2 stops10h 12m

$323

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

Sat 8/22

5:40 am-11:28 am

1 stop7h 48m

San Jose

Mon 8/31

8:53 pm-10:18 am

2 stops11h 25m

$324

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Des Moines to San Jose, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Des Moines and San Jose, California?

What is the cheapest month to fly to San Jose, California?

The month of February is, on average, the cheapest month to fly to San Jose, California from Des Moines, with most prices found around $367. If you are unable to visit San Jose, California during the month of February, then departing from Des Moines during the month December is also very affordable. Most momondo users find prices during this month for around $392.

When to book flights from Des Moines to San Jose, California

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to San Jose, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to San Jose, California (DSM to SJC) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to San Jose, California

Fastest flight time

5h 25m

Direct flights

None
The fastest flight from Des Moines to San Jose, California takes 5h 25m
There are no direct flights from Des Moines to San Jose, California. There are no popular flight routes from Des Moines to San Jose, California.
Search flight deals

Frequently asked questions about flying from Des Moines to San Jose, California

  • How far is Des Moines to San Jose by plane?

    The straight-line distance from Des Moines to San Jose is 1527.5 mi. 5h 25m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to San Jose Airport?

    Prices for flights from Des Moines Airport to San Jose Airport are updated daily.

  • How many operators does momondo search for flights from Des Moines Airport to San Jose Airport?

  • How old do you have to be to fly from Des Moines Airport to San Jose Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to San Jose Airport.

  • What documentation or ID do you need to fly to San Jose Airport?

    The travel and health documents you'll need for your trip to San Jose Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Jose Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to San Jose, California?

Best airlines flying from Des Moines to San Jose, California

Compare and see reviews for airlines that fly from Des Moines to San Jose, California with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $179Free CancellationRating
7.9
8,406 reviews
Search Delta flights
United AirlinesPriceFrom $300Free CancellationRating
7.4
9,815 reviews
Search United Airlines flights
American AirlinesPriceFrom $332Free CancellationRating
7.1
11,649 reviews
Search American Airlines flights
SouthwestPriceFrom $344Free CancellationRating
7.9
4,235 reviews
Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to San Jose?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Des Moines to San Jose. momondo saves you time and could save you money on your trip.

Can I find flights from Des Moines to San Jose with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Jose from Des Moines with this policy.

How can momondo help me find flights from Des Moines to San Jose?

momondo provides multiple filters to help you find the best flight to San Jose from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to San Jose right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to San Jose flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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