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Cheap flights from Des Moines to San Diego from $73

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to San Diego departing on 7/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Allegiant Air Logo
2:39 pm - 4:10 pmDSM-SAN
3h 31mnonstop
Allegiant Air Logo
5:00 pm - 10:35 pmSAN-DSM
3h 35mnonstop
$111Allegiant Air
Find Deal
vie., jul. 18 - lun., jul. 28
Allegiant Air Logo
2:39 pm - 4:10 pmDSM-SAN
3h 31mnonstop
Allegiant Air Logo
5:00 pm - 10:35 pmSAN-DSM
3h 35mnonstop
$116Allegiant Air
Find Deal
vie., jul. 18 - lun., jul. 28
Frontier Logo
3:30 pm - 11:50 pmDSM-SAN
10h 20m1 stop
Frontier Logo
6:25 am - 7:59 pmSAN-DSM
11h 34m1 stop
$265Frontier
Find Deal
mié., oct. 15 - lun., oct. 20
Frontier Logo
8:38 pm - 11:55 pmDSM-SAN
5h 17m1 stop
Frontier Logo
6:25 am - 6:48 pmSAN-DSM
10h 23m1 stop
$270Frontier
Find Deal
lun., jun. 30 - lun., jul. 7
United Airlines Logo
5:15 pm - 8:25 pmDSM-SAN
5h 10m1 stop
United Airlines Logo
2:21 pm - 11:41 pmSAN-DSM
7h 20m2 stops
$292United Airlines
Find Deal
mié., ago. 27 - mar., sep. 2
American Airlines Logo
7:47 pm - 12:09 amDSM-SAN
6h 22m1 stop
American Airlines Logo
10:45 pm - 9:33 amSAN-DSM
8h 48m1 stop
$321American Airlines
Find Deal
sáb., jul. 26 - sáb., ago. 2
American Airlines Logo
7:47 pm - 12:09 amDSM-SAN
6h 22m1 stop
American Airlines Logo
10:45 pm - 9:33 amSAN-DSM
8h 48m1 stop
$322American Airlines
Find Deal
sáb., jul. 26 - sáb., ago. 2
Southwest Logo
3:00 pm - 6:25 pmDSM-SAN
5h 25m1 stop
Southwest Logo
6:35 am - 4:00 pmSAN-DSM
7h 25m2 stops
$348Southwest
Find Deal
mié., oct. 8 - mié., oct. 15
United Airlines Logo
11:35 am - 6:20 pmDSM-SAN
8h 45m1 stop
United Airlines Logo
2:21 pm - 11:41 pmSAN-DSM
7h 20m2 stops
$372United Airlines
Find Deal
vie., ago. 22 - lun., ago. 25
Southwest Logo
6:10 am - 3:25 pmDSM-SAN
11h 15m2 stops
Southwest Logo
6:45 am - 4:50 pmSAN-DSM
8h 05m1 stop
$380Southwest
Find Deal
vie., jul. 4 - mar., jul. 8

Allegiant Air flights from Des Moines to San Diego

Our best Allegiant Air deals on Des Moines to San Diego flight tickets
Allegiant Air
Jul 18
DSM2:39 pmDes Moines
3h 31m
SAN4:10 pmSan Diego
Jul 28
SAN5:00 pmSan Diego
3h 35m
DSM10:35 pmDes Moines
Allegiant Air
Jul 18
DSM2:39 pmDes Moines
3h 31m
SAN4:10 pmSan Diego
Jul 28
SAN5:00 pmSan Diego
3h 35m
DSM10:35 pmDes Moines
Allegiant Air
Jul 25
DSM2:39 pmDes Moines
3h 31m
SAN4:10 pmSan Diego
Jul 28
SAN5:00 pmSan Diego
3h 35m
DSM10:35 pmDes Moines

Delta flights from Des Moines to San Diego

Our best Delta deals on Des Moines to San Diego flight tickets
Delta
Oct 7
DSM10:15 amDes Moines
10h 11m
1 stop
SAN6:26 pmSan Diego
Oct 13
SAN10:30 pmSan Diego
8h 52m
1 stop
DSM9:22 amDes Moines
Delta
Jul 4
DSM7:00 amDes Moines
7h 49m
1 stop
SAN12:49 pmSan Diego
Jul 12
SAN10:15 pmSan Diego
9h 23m
1 stop
DSM9:38 amDes Moines
Delta
Jul 8
DSM6:05 amDes Moines
9h 48m
1 stop
SAN1:53 pmSan Diego
Jul 9
SAN6:25 amSan Diego
8h 44m
1 stop
DSM5:09 pmDes Moines

See travel insights to San Diego from

How to get the cheapest flight ticket from Des Moines to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of June, then departing from Des Moines during the month July is also very affordable. Most momondo users find prices during this month for around $286.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Des Moines to San Diego is on a Tuesday. Travelers who choose to depart for San Diego on a Tuesday will often find tickets for as low as $179. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $468. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is at noon when flights can be purchased for as low as $196. Flights in the morning are often more expensive with an average ticket price of $433.

What is the cheapest Des Moines to San Diego flight route?

Fly from Des Moines to San Diego for the best Des Moines - San Diego flight prices

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Des Moines when booking 15 weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $385 when searching 15 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Des Moines for as low as $268 on momondo.

What cabin class options are available on Des Moines to San Diego flights?

There are 1 cabin classes available to choose from on Des Moines to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Des Moines to San Diego flights?

No. A direct flight is the cheapest option for a flight between Des Moines to San Diego.

How have Des Moines to San Diego flight prices changed over time?

As of June 2025, prices for Des Moines to San Diego flights are approximately 31% cheaper when compared to flights at the same time last year.

When to book flights from Des Moines to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to San Diego (DSM to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to San Diego

Best Price Found

$73

Fastest flight time

3h 31m

Direct flights

Tue and Sat

Airports in San Diego

1 airport
The best one-way flight to San Diego from Des Moines in the past 72 hours is $73. The best round-trip flight deal from Des Moines to San Diego found on momondo in the last 72 hours is $111.
The fastest flight from Des Moines to San Diego takes 3h 31m
Direct flights go from Des Moines to San Diego on Tuesday and Saturday. The only airline offering direct flights is Allegiant Air.
There is 1 airport near San Diego: San Diego (SAN)

  • How far is Des Moines to San Diego by plane?

    Des Moines and San Diego are 1426.2 mi apart from one another. In terms of flight time, this usually takes a little over 3h 31m.

  • When did momondo last update prices for flights from Des Moines Airport to San Diego Airport?

    Prices for flights from Des Moines Airport to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to San Diego Airport?

  • How old do you have to be to fly from Des Moines Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Des Moines to San Diego?

  • What is the most popular airline from Des Moines to San Diego?


Best airlines flying from Des Moines to San Diego

Compare and see reviews for airlines that fly from Des Moines to San Diego with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $104Free CancellationRating
7.3
725 reviews
Search Allegiant Air flights
FrontierPriceFrom $125Free CancellationRating
5.9
3,295 reviews
Search Frontier flights
American AirlinesPriceFrom $286Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $286Free CancellationRating
8.0
7,946 reviews
Search Delta flights
United AirlinesPriceFrom $313Free CancellationRating
7.4
8,790 reviews
Search United Airlines flights
SouthwestPriceFrom $359Free CancellationRating
8.0
4,287 reviews
Search Southwest flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
La Mesa
Imperial Beach
San Ysidro
Poway
Borrego Springs
Lemon Grove
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to San Diego?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Diego from Des Moines.

Can I find flights from Des Moines to San Diego with flexible booking policies on momondo?

Flights from Des Moines to San Diego with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Des Moines to San Diego?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to San Diego from Des Moines.

I’m not ready to book a flight from Des Moines to San Diego right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to San Diego flights. All you need is a valid email address and we will do the rest; it is that quick and easy.


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1 adult
mar. 6/17
mar. 6/24

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