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Cheap flights from Des Moines to Sao Paulo from $739

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Sao Paulo departing on 4/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:30 am - 8:40 pm
DSM
-
GRU
35h 10m
1 stop
Multiple Airlines Logo
5:20 am - 3:24 pm
GRU
-
DSM
36h 04m
2 stops
$1,063Multiple Airlines
Sun, Jun 21 - Mon, Aug 3
Multiple Airlines Logo
7:30 am - 8:40 pm
DSM
-
GRU
35h 10m
1 stop
Multiple Airlines Logo
5:15 pm - 3:50 pm
GRU
-
DSM
48h 35m
2 stops
$1,146Multiple Airlines
Sun, Jun 21 - Sat, Aug 1
LATAM Airlines Logo
6:30 pm - 8:00 pm
DSM
-
GRU
23h 30m
2 stops
LATAM Airlines Logo
11:45 pm - 5:42 pm
GRU
-
DSM
19h 57m
2 stops
$1,159LATAM Airlines
Sun, Sep 13 - Sun, Sep 20
LATAM Airlines Logo
2:15 pm - 5:40 am
DSM
-
GRU
13h 25m
1 stop
LATAM Airlines Logo
9:30 pm - 1:22 pm
GRU
-
DSM
41h 52m
2 stops
$1,192LATAM Airlines
Sat, Sep 19 - Sat, Sep 26
LATAM Airlines Logo
6:30 pm - 8:00 pm
DSM
-
GRU
23h 30m
2 stops
LATAM Airlines Logo
10:50 pm - 10:14 am
GRU
-
DSM
13h 24m
1 stop
$1,197LATAM Airlines
Sun, Sep 13 - Sun, Sep 20
LATAM Airlines Logo
6:30 pm - 8:00 pm
DSM
-
GRU
23h 30m
2 stops
LATAM Airlines Logo
11:45 pm - 5:42 pm
GRU
-
DSM
19h 57m
2 stops
$1,199LATAM Airlines
Sun, Sep 13 - Sun, Sep 20
LATAM Airlines Logo
11:04 am - 5:40 am
DSM
-
GRU
16h 36m
1 stop
LATAM Airlines Logo
11:45 pm - 5:42 pm
GRU
-
DSM
19h 57m
2 stops
$1,205LATAM Airlines
Sun, Sep 13 - Sun, Sep 20
United Airlines Logo
3:24 pm - 9:35 am
DSM
-
GRU
16h 11m
1 stop
United Airlines Logo
9:50 pm - 2:05 pm
GRU
-
DSM
18h 15m
2 stops
$1,208United Airlines
Sat, Aug 29 - Mon, Sep 7
United Airlines Logo
8:30 pm - 9:40 am
DSM
-
GRU
35h 10m
1 stop
United Airlines Logo
9:50 pm - 2:17 pm
GRU
-
DSM
18h 27m
1 stop
$1,220United Airlines
Sun, Sep 13 - Sun, Sep 20
United Airlines Logo
8:30 pm - 9:40 am
DSM
-
GRU
35h 10m
1 stop
United Airlines Logo
9:50 pm - 5:02 pm
GRU
-
DSM
21h 12m
2 stops
$1,225United Airlines
Sun, Sep 13 - Sun, Sep 20

United Airlines flights from Des Moines to Sao Paulo

Our best United Airlines deals on Des Moines to Sao Paulo flight tickets
United Airlines
Aug 29
DSM3:24 pmDes Moines
16h 11m
1 stop
GRU9:35 amSao Paulo Guarulhos Intl
Sep 7
GRU9:50 pmSao Paulo Guarulhos Intl
18h 15m
2 stops
DSM2:05 pmDes Moines
$1,208
United Airlines
Sep 13
DSM8:30 pmDes Moines
35h 10m
1 stop
GRU9:40 amSao Paulo Guarulhos Intl
Sep 20
GRU9:50 pmSao Paulo Guarulhos Intl
18h 27m
1 stop
DSM2:17 pmDes Moines
$1,220
United Airlines
Sep 13
DSM8:30 pmDes Moines
35h 10m
1 stop
GRU9:40 amSao Paulo Guarulhos Intl
Sep 20
GRU9:50 pmSao Paulo Guarulhos Intl
21h 12m
2 stops
DSM5:02 pmDes Moines
$1,225

LATAM Airlines flights from Des Moines to Sao Paulo

Our best LATAM Airlines deals on Des Moines to Sao Paulo flight tickets
LATAM Airlines
Sep 13
DSM6:30 pmDes Moines
23h 30m
2 stops
GRU8:00 pmSao Paulo Guarulhos Intl
Sep 20
GRU11:45 pmSao Paulo Guarulhos Intl
19h 57m
2 stops
DSM5:42 pmDes Moines
$1,159
LATAM Airlines
Sep 19
DSM2:15 pmDes Moines
13h 25m
1 stop
GRU5:40 amSao Paulo Guarulhos Intl
Sep 26
GRU9:30 pmSao Paulo Guarulhos Intl
41h 52m
2 stops
DSM1:22 pmDes Moines
$1,192
LATAM Airlines
Sep 13
DSM6:30 pmDes Moines
23h 30m
2 stops
GRU8:00 pmSao Paulo Guarulhos Intl
Sep 20
GRU10:50 pmSao Paulo Guarulhos Intl
13h 24m
1 stop
DSM10:14 amDes Moines
$1,197

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Sao Paulo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 26, 2026.
Use the filters below to find and compare flights from Des Moines to Sao Paulo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sun 6/21

7:30 am-8:40 pm

1 stop35h 10m

Sao Paulo Guarulhos Intl

Mon 8/3

5:20 am-3:24 pm

2 stops36h 04m

$1,063

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sun 6/21

7:30 am-8:40 pm

1 stop35h 10m

Sao Paulo Guarulhos Intl

Sat 8/1

5:15 pm-3:50 pm

2 stops48h 35m

$1,146

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sun 9/13

6:30 pm-8:00 pm

2 stops23h 30m

Sao Paulo Guarulhos Intl

Sun 9/20

11:45 pm-5:42 pm

2 stops19h 57m

$1,159

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sat 9/19

2:15 pm-5:40 am

1 stop13h 25m

Sao Paulo Guarulhos Intl

Sat 9/26

9:30 pm-1:22 pm

2 stops41h 52m

$1,192

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sun 9/13

6:30 pm-8:00 pm

2 stops23h 30m

Sao Paulo Guarulhos Intl

Sun 9/20

10:50 pm-10:14 am

1 stop13h 24m

$1,197

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sun 9/13

6:30 pm-8:00 pm

2 stops23h 30m

Sao Paulo Guarulhos Intl

Sun 9/20

11:45 pm-5:42 pm

2 stops19h 57m

$1,199

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sun 9/13

11:04 am-5:40 am

1 stop16h 36m

Sao Paulo Guarulhos Intl

Sun 9/20

11:45 pm-5:42 pm

2 stops19h 57m

$1,205
Quickest round-trip

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sat 8/29

3:24 pm-9:35 am

1 stop16h 11m

Sao Paulo Guarulhos Intl

Mon 9/7

9:50 pm-2:05 pm

2 stops18h 15m

$1,208

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sun 9/13

8:30 pm-9:40 am

1 stop35h 10m

Sao Paulo Guarulhos Intl

Sun 9/20

9:50 pm-2:17 pm

1 stop18h 27m

$1,220

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sun 9/13

8:30 pm-9:40 am

1 stop35h 10m

Sao Paulo Guarulhos Intl

Sun 9/20

9:50 pm-5:02 pm

2 stops21h 12m

$1,225

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Sao Paulo from

How to get the cheapest flight ticket from Des Moines to Sao Paulo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Des Moines to Sao Paulo?

Avianca, LATAM Airlines, and United Airlines are the most popular carriers operating from Des Moines to Sao Paulo

When to book flights from Des Moines to Sao Paulo

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Sao Paulo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Sao Paulo (DSM to SAO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Sao Paulo

Fastest flight time

27h 44m

Direct flights

None
The fastest flight from Des Moines to Sao Paulo takes 27h 44m
There are no direct flights from Des Moines to Sao Paulo. There are no popular flight routes from Des Moines to Sao Paulo.
Search flight deals

  • How far is Des Moines to Sao Paulo by plane?

    Des Moines and Sao Paulo are 5407.3 mi apart from one another. 27h 44m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to Sao Paulo?

    Prices for flights from Des Moines Airport to Sao Paulo were last updated today.

  • How old do you have to be to fly from Des Moines Airport to Sao Paulo?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Sao Paulo.

  • What documentation or ID do you need to fly to Sao Paulo?

    The necessary travel and health documents for your Sao Paulo trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Sao Paulo?

Book flights to Sao Paulo if you plan to visit one of these locations
Santos
Guarujá

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Sao Paulo?

It is quick and easy to find Des Moines to Sao Paulo flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Sao Paulo that suits you.

Can I find flights from Des Moines to Sao Paulo with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Sao Paulo from Des Moines with this policy.

How can momondo help me find flights from Des Moines to Sao Paulo?

momondo helps you find the best flight between Des Moines and Sao Paulo by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Sao Paulo right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Sao Paulo, momondo offers a useful price alert feature which will track prices for flights to Sao Paulo from Des Moines and alert you when they change.

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Find better results for your trip to Brazil

Fly into one of these airports located in Sao Paulo

Airports listed have a maximum distance of 48.9 mi from Sao Paulo
Sao Paulo Congonhas Airport
Sao Paulo Guarulhos Intl Airport
Sao Paulo Viracopos Airport