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Cheap flights from Des Moines to Sao Paulo from $459

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Sao Paulo departing on 3/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
10:20 am - 12:10 am
DSM
-
GRU
35h 50m
2 stops
Multiple Airlines Logo
10:50 pm - 10:48 am
GRU
-
DSM
13h 58m
1 stop
$980Multiple Airlines
Mon, Mar 23 - Mon, Mar 30
LATAM Airlines Logo
2:33 pm - 4:15 pm
DSM
-
GRU
23h 42m
2 stops
LATAM Airlines Logo
8:30 am - 10:26 pm
GRU
-
DSM
15h 56m
2 stops
$1,124LATAM Airlines
Tue, Jun 2 - Tue, Jun 16
LATAM Airlines Logo
2:33 pm - 5:40 am
DSM
-
GRU
13h 07m
1 stop
LATAM Airlines Logo
2:55 pm - 10:14 am
GRU
-
DSM
21h 19m
2 stops
$1,128LATAM Airlines
Tue, Jun 2 - Tue, Jun 16
United Airlines Logo
8:15 pm - 9:30 am
DSM
-
GRU
35h 15m
1 stop
United Airlines Logo
9:50 pm - 2:13 pm
GRU
-
DSM
18h 23m
1 stop
$1,135United Airlines
Tue, Jun 2 - Tue, Jun 16
Multiple Airlines Logo
10:20 am - 7:50 am
DSM
-
GRU
19h 30m
1 stop
Multiple Airlines Logo
10:50 pm - 10:48 am
GRU
-
DSM
13h 58m
1 stop
$1,144Multiple Airlines
Mon, Mar 23 - Mon, Mar 30
Multiple Airlines Logo
8:21 pm - 5:20 am
DSM
-
GRU
30h 59m
2 stops
Multiple Airlines Logo
10:45 pm - 1:46 pm
GRU
-
DSM
17h 01m
1 stop
$1,183Multiple Airlines
Wed, Mar 25 - Wed, Apr 1
LATAM Airlines Logo
5:35 am - 5:40 am
DSM
-
GRU
22h 05m
1 stop
LATAM Airlines Logo
10:50 pm - 10:48 am
GRU
-
DSM
13h 58m
1 stop
$1,270LATAM Airlines
Thu, Mar 26 - Thu, Apr 2
American Airlines Logo
3:26 pm - 8:10 am
DSM
-
GRU
14h 44m
1 stop
American Airlines Logo
10:00 pm - 10:34 am
GRU
-
DSM
14h 34m
1 stop
$1,281American Airlines
Mon, Mar 23 - Mon, Mar 30
American Airlines Logo
3:26 pm - 8:10 am
DSM
-
GRU
14h 44m
1 stop
American Airlines Logo
10:00 pm - 10:34 am
GRU
-
DSM
14h 34m
1 stop
$1,282American Airlines
Mon, Mar 23 - Mon, Mar 30
United Airlines Logo
11:26 am - 7:15 am
DSM
-
GRU
17h 49m
1 stop
United Airlines Logo
10:20 pm - 2:25 pm
GRU
-
DSM
18h 05m
1 stop
$1,283United Airlines
Tue, Mar 24 - Tue, Mar 31

LATAM Airlines flights from Des Moines to Sao Paulo

Our best LATAM Airlines deals on Des Moines to Sao Paulo flight tickets
LATAM Airlines
Jun 2
DSM2:33 pmDes Moines
23h 42m
2 stops
GRU4:15 pmSao Paulo Guarulhos Intl
Jun 16
GRU8:30 amSao Paulo Guarulhos Intl
15h 56m
2 stops
DSM10:26 pmDes Moines
$1,124
LATAM Airlines
Jun 2
DSM2:33 pmDes Moines
13h 07m
1 stop
GRU5:40 amSao Paulo Guarulhos Intl
Jun 16
GRU2:55 pmSao Paulo Guarulhos Intl
21h 19m
2 stops
DSM10:14 amDes Moines
$1,128
LATAM Airlines
Mar 26
DSM5:35 amDes Moines
22h 05m
1 stop
GRU5:40 amSao Paulo Guarulhos Intl
Apr 2
GRU10:50 pmSao Paulo Guarulhos Intl
13h 58m
1 stop
DSM10:48 amDes Moines
$1,270

United Airlines flights from Des Moines to Sao Paulo

Our best United Airlines deals on Des Moines to Sao Paulo flight tickets
United Airlines
Jun 2
DSM8:15 pmDes Moines
35h 15m
1 stop
GRU9:30 amSao Paulo Guarulhos Intl
Jun 16
GRU9:50 pmSao Paulo Guarulhos Intl
18h 23m
1 stop
DSM2:13 pmDes Moines
$1,135
United Airlines
Mar 24
DSM2:04 pmDes Moines
15h 46m
2 stops
GRU7:50 amSao Paulo Guarulhos Intl
Mar 31
GRU10:20 pmSao Paulo Guarulhos Intl
16h 09m
1 stop
DSM12:29 pmDes Moines
$1,283
United Airlines
Mar 23
DSM3:28 pmDes Moines
16h 52m
2 stops
GRU10:20 amSao Paulo Guarulhos Intl
Mar 30
GRU10:20 pmSao Paulo Guarulhos Intl
14h 24m
1 stop
DSM10:44 amDes Moines
$1,293

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Sao Paulo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 9, 2026.
Use the filters below to find and compare flights from Des Moines to Sao Paulo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Mon 3/23

10:20 am-12:10 am

2 stops35h 50m

Sao Paulo Guarulhos Intl

Mon 3/30

10:50 pm-10:48 am

1 stop13h 58m

$980

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Tue 6/2

2:33 pm-4:15 pm

2 stops23h 42m

Sao Paulo Guarulhos Intl

Tue 6/16

8:30 am-10:26 pm

2 stops15h 56m

$1,124

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Tue 6/2

2:33 pm-5:40 am

1 stop13h 07m

Sao Paulo Guarulhos Intl

Tue 6/16

2:55 pm-10:14 am

2 stops21h 19m

$1,128

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Tue 6/2

8:15 pm-9:30 am

1 stop35h 15m

Sao Paulo Guarulhos Intl

Tue 6/16

9:50 pm-2:13 pm

1 stop18h 23m

$1,135

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Mon 3/23

10:20 am-7:50 am

1 stop19h 30m

Sao Paulo Guarulhos Intl

Mon 3/30

10:50 pm-10:48 am

1 stop13h 58m

$1,144

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Wed 3/25

8:21 pm-5:20 am

2 stops30h 59m

Sao Paulo Guarulhos Intl

Wed 4/1

10:45 pm-1:46 pm

1 stop17h 01m

$1,183

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Thu 3/26

5:35 am-5:40 am

1 stop22h 05m

Sao Paulo Guarulhos Intl

Thu 4/2

10:50 pm-10:48 am

1 stop13h 58m

$1,270

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Mon 3/23

3:26 pm-8:10 am

1 stop14h 44m

Sao Paulo Guarulhos Intl

Mon 3/30

10:00 pm-10:34 am

1 stop14h 34m

$1,281

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Mon 3/23

3:26 pm-8:10 am

1 stop14h 44m

Sao Paulo Guarulhos Intl

Mon 3/30

10:00 pm-10:34 am

1 stop14h 34m

$1,282

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Tue 3/24

11:26 am-7:15 am

1 stop17h 49m

Sao Paulo Guarulhos Intl

Tue 3/31

10:20 pm-2:25 pm

1 stop18h 05m

$1,283

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Sao Paulo from

How to get the cheapest flight ticket from Des Moines to Sao Paulo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Des Moines to Sao Paulo?

LATAM Airlines, United Airlines, and American Airlines are the most popular carriers operating from Des Moines to Sao Paulo

When to book flights from Des Moines to Sao Paulo

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Sao Paulo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Sao Paulo (DSM to SAO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Sao Paulo

Fastest flight time

19h 01m

Direct flights

None
The fastest flight from Des Moines to Sao Paulo takes 19h 01m
There are no direct flights from Des Moines to Sao Paulo. There are no popular flight routes from Des Moines to Sao Paulo.
Search flight deals

  • How far is Des Moines to Sao Paulo by plane?

    Des Moines and Sao Paulo are 5407.3 mi apart from one another. 19h 01m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to Sao Paulo?

    Prices for flights from Des Moines Airport to Sao Paulo were last updated today.

  • How old do you have to be to fly from Des Moines Airport to Sao Paulo?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Sao Paulo.

  • What documentation or ID do you need to fly to Sao Paulo?

    The necessary travel and health documents for your Sao Paulo trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Sao Paulo?

Book flights to Sao Paulo if you plan to visit one of these locations
Santos
Guarujá

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Sao Paulo?

It is quick and easy to find Des Moines to Sao Paulo flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Sao Paulo that suits you.

Can I find flights from Des Moines to Sao Paulo with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Sao Paulo from Des Moines with this policy.

How can momondo help me find flights from Des Moines to Sao Paulo?

momondo helps you find the best flight between Des Moines and Sao Paulo by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Sao Paulo right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Sao Paulo, momondo offers a useful price alert feature which will track prices for flights to Sao Paulo from Des Moines and alert you when they change.

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Find better results for your trip to Brazil

Fly into one of these airports located in Sao Paulo

Airports listed have a maximum distance of 48.9 mi from Sao Paulo
Sao Paulo Congonhas Airport
Sao Paulo Guarulhos Intl Airport
Sao Paulo Viracopos Airport