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Cheap flights from Des Moines to Sao Paulo from $738

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Sao Paulo departing on 6/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Des Moines to Sao Paulo

Cheap round-trip flights

Enter your travel dates to find the best prices.
LATAM Airlines Logo
5:00 pm - 5:05 am
DSM
-
GRU
34h 05m
2 stops
LATAM Airlines Logo
8:00 am - 5:52 pm
GRU
-
DSM
35h 52m
2 stops
$1,232LATAM Airlines
Thu, Jul 2 - Thu, Jul 9
LATAM Airlines Logo
5:00 pm - 4:10 pm
DSM
-
GRU
21h 10m
2 stops
LATAM Airlines Logo
10:50 pm - 10:45 am
GRU
-
DSM
13h 55m
1 stop
$1,264LATAM Airlines
Wed, Jul 1 - Wed, Jul 8
LATAM Airlines Logo
5:00 pm - 4:10 pm
DSM
-
GRU
21h 10m
2 stops
LATAM Airlines Logo
10:45 pm - 10:29 pm
GRU
-
DSM
25h 44m
2 stops
$1,269LATAM Airlines
Wed, Jul 1 - Wed, Jul 8
Multiple Airlines Logo
2:16 pm - 7:50 am
DSM
-
GRU
39h 34m
2 stops
Multiple Airlines Logo
11:40 am - 8:37 am
GRU
-
DSM
22h 57m
1 stop
$1,337Multiple Airlines
Wed, Jun 17 - Wed, Jun 24
Multiple Airlines Logo
7:30 am - 8:40 pm
DSM
-
GRU
35h 10m
1 stop
Multiple Airlines Logo
4:08 am - 1:50 pm
GRU
-
DSM
35h 42m
2 stops
$1,383Multiple Airlines
Sun, Jun 21 - Sun, Jun 28
LATAM Airlines Logo
5:00 pm - 1:25 pm
DSM
-
GRU
18h 25m
2 stops
LATAM Airlines Logo
10:50 pm - 1:34 pm
GRU
-
DSM
16h 44m
1 stop
$1,396LATAM Airlines
Mon, Jun 29 - Mon, Jul 6
Multiple Airlines Logo
2:16 pm - 5:30 am
DSM
-
GRU
37h 14m
2 stops
Multiple Airlines Logo
10:50 pm - 10:45 am
GRU
-
DSM
13h 55m
1 stop
$1,412Multiple Airlines
Wed, Jul 1 - Wed, Jul 8
United Airlines Logo
3:24 pm - 9:30 am
DSM
-
GRU
16h 06m
2 stops
United Airlines Logo
10:20 pm - 10:17 am
GRU
-
DSM
13h 57m
1 stop
$1,418United Airlines
Thu, Jul 2 - Thu, Jul 9
American Airlines Logo
9:41 am - 5:55 am
DSM
-
GRU
18h 14m
2 stops
American Airlines Logo
9:25 pm - 1:05 pm
GRU
-
DSM
17h 40m
2 stops
$1,430American Airlines
Tue, Jun 30 - Tue, Jul 7
LATAM Airlines Logo
5:00 pm - 3:45 pm
DSM
-
GRU
20h 45m
2 stops
LATAM Airlines Logo
11:45 pm - 5:52 pm
GRU
-
DSM
20h 07m
2 stops
$1,433LATAM Airlines
Thu, Jul 2 - Thu, Jul 9

LATAM Airlines flights from Des Moines to Sao Paulo

Our best LATAM Airlines deals on Des Moines to Sao Paulo flight tickets
LATAM Airlines
Jul 2
DSM5:00 pmDes Moines
34h 05m
2 stops
GRU5:05 amSao Paulo Guarulhos Intl
Jul 9
GRU8:00 amSao Paulo Guarulhos Intl
35h 52m
2 stops
DSM5:52 pmDes Moines
$1,232
LATAM Airlines
Jul 1
DSM5:00 pmDes Moines
21h 10m
2 stops
GRU4:10 pmSao Paulo Guarulhos Intl
Jul 8
GRU10:50 pmSao Paulo Guarulhos Intl
13h 55m
1 stop
DSM10:45 amDes Moines
$1,264
LATAM Airlines
Jul 1
DSM5:00 pmDes Moines
21h 10m
2 stops
GRU4:10 pmSao Paulo Guarulhos Intl
Jul 8
GRU10:45 pmSao Paulo Guarulhos Intl
25h 44m
2 stops
DSM10:29 pmDes Moines
$1,269

United Airlines flights from Des Moines to Sao Paulo

Our best United Airlines deals on Des Moines to Sao Paulo flight tickets
United Airlines
Sep 13
DSM6:55 pmDes Moines
33h 35m
2 stops
GRU6:30 amSao Paulo Guarulhos Intl
Sep 20
GRU10:20 pmSao Paulo Guarulhos Intl
18h 00m
1 stop
DSM2:20 pmDes Moines
$1,267
United Airlines
Sep 13
DSM6:55 pmDes Moines
33h 35m
2 stops
GRU6:30 amSao Paulo Guarulhos Intl
Sep 20
GRU9:30 pmSao Paulo Guarulhos Intl
18h 50m
2 stops
DSM2:20 pmDes Moines
$1,268
United Airlines
Jul 2
DSM6:50 pmDes Moines
12h 50m
1 stop
GRU9:40 amSao Paulo Guarulhos Intl
Jul 9
GRU10:20 pmSao Paulo Guarulhos Intl
21h 53m
1 stop
DSM6:13 pmDes Moines
$1,418

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Sao Paulo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 20, 2026.
Use the filters below to find and compare flights from Des Moines to Sao Paulo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Thu 7/2

5:00 pm-5:05 am

2 stops34h 05m

Sao Paulo Guarulhos Intl

Thu 7/9

8:00 am-5:52 pm

2 stops35h 52m

$1,232

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Wed 7/1

5:00 pm-4:10 pm

2 stops21h 10m

Sao Paulo Guarulhos Intl

Wed 7/8

10:50 pm-10:45 am

1 stop13h 55m

$1,264

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Wed 7/1

5:00 pm-4:10 pm

2 stops21h 10m

Sao Paulo Guarulhos Intl

Wed 7/8

10:45 pm-10:29 pm

2 stops25h 44m

$1,269

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Wed 6/17

2:16 pm-7:50 am

2 stops39h 34m

Sao Paulo Guarulhos Intl

Wed 6/24

11:40 am-8:37 am

1 stop22h 57m

$1,337

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sun 6/21

7:30 am-8:40 pm

1 stop35h 10m

Sao Paulo Guarulhos Intl

Sun 6/28

4:08 am-1:50 pm

2 stops35h 42m

$1,383

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Mon 6/29

5:00 pm-1:25 pm

2 stops18h 25m

Sao Paulo Guarulhos Intl

Mon 7/6

10:50 pm-1:34 pm

1 stop16h 44m

$1,396

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Wed 7/1

2:16 pm-5:30 am

2 stops37h 14m

Sao Paulo Guarulhos Intl

Wed 7/8

10:50 pm-10:45 am

1 stop13h 55m

$1,412
Quickest round-trip

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Thu 7/2

3:24 pm-9:30 am

2 stops16h 06m

Sao Paulo Guarulhos Intl

Thu 7/9

10:20 pm-10:17 am

1 stop13h 57m

$1,418

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Tue 6/30

9:41 am-5:55 am

2 stops18h 14m

Sao Paulo Guarulhos Intl

Tue 7/7

9:25 pm-1:05 pm

2 stops17h 40m

$1,430

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Thu 7/2

5:00 pm-3:45 pm

2 stops20h 45m

Sao Paulo Guarulhos Intl

Thu 7/9

11:45 pm-5:52 pm

2 stops20h 07m

$1,433

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 11 resultsSorted by cheapest first
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See travel insights to Sao Paulo from

How to get the cheapest flight ticket from Des Moines to Sao Paulo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Des Moines to Sao Paulo?

Copa Airlines, LATAM Airlines, and American Airlines are the most popular carriers operating from Des Moines to Sao Paulo

When to book flights from Des Moines to Sao Paulo

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Sao Paulo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Sao Paulo (DSM to SAO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Sao Paulo

Fastest flight time

13h 29m

Direct flights

None
The fastest flight from Des Moines to Sao Paulo takes 13h 29m
There are no direct flights from Des Moines to Sao Paulo. There are no popular flight routes from Des Moines to Sao Paulo.
Search flight deals

Frequently asked questions about flying from Des Moines to Sao Paulo

  • How far is Des Moines to Sao Paulo by plane?

    Des Moines and Sao Paulo are 5407.3 mi apart from one another. 13h 29m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to Sao Paulo?

    Prices for flights from Des Moines Airport to Sao Paulo were last updated today.

  • How old do you have to be to fly from Des Moines Airport to Sao Paulo?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Sao Paulo.

  • What documentation or ID do you need to fly to Sao Paulo?

    The necessary travel and health documents for your Sao Paulo trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Sao Paulo?

Traveling to a place near Sao Paulo?

Book flights to Sao Paulo if you plan to visit one of these locations
Santos
Guarujá

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Sao Paulo?

It is quick and easy to find Des Moines to Sao Paulo flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Sao Paulo that suits you.

Can I find flights from Des Moines to Sao Paulo with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Sao Paulo from Des Moines with this policy.

How can momondo help me find flights from Des Moines to Sao Paulo?

momondo helps you find the best flight between Des Moines and Sao Paulo by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Sao Paulo right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Sao Paulo, momondo offers a useful price alert feature which will track prices for flights to Sao Paulo from Des Moines and alert you when they change.

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Find better results for your trip to Brazil

Fly into one of these airports located in Sao Paulo

Airports listed have a maximum distance of 48.9 mi from Sao Paulo
Sao Paulo Congonhas Airport
Sao Paulo Guarulhos Intl Airport
Sao Paulo Viracopos Airport