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Cheap flights from Des Moines to Sao Paulo from $393

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Sao Paulo departing on 8/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Des Moines to Sao Paulo

Cheap round-trip flights

Enter your travel dates to find the best prices.
LATAM Airlines Logo
6:35 pm - 5:00 am
DSM
-
GRU
32h 25m
2 stops
LATAM Airlines Logo
5:45 pm - 5:50 pm
GRU
-
DSM
26h 05m
2 stops
$1,003LATAM Airlines
Mon, Aug 17 - Mon, Aug 24
LATAM Airlines Logo
6:35 pm - 5:40 am
DSM
-
GRU
33h 05m
1 stop
LATAM Airlines Logo
8:45 pm - 10:43 am
GRU
-
DSM
39h 58m
2 stops
$1,030LATAM Airlines
Wed, Aug 12 - Wed, Aug 19
LATAM Airlines Logo
6:35 pm - 5:00 am
DSM
-
GRU
32h 25m
2 stops
LATAM Airlines Logo
1:05 pm - 5:50 pm
GRU
-
DSM
30h 45m
2 stops
$1,046LATAM Airlines
Wed, Aug 19 - Wed, Aug 26
LATAM Airlines Logo
6:35 pm - 5:00 am
DSM
-
GRU
32h 25m
2 stops
LATAM Airlines Logo
8:45 pm - 10:43 am
GRU
-
DSM
39h 58m
2 stops
$1,047LATAM Airlines
Wed, Aug 12 - Wed, Aug 19
LATAM Airlines Logo
2:54 pm - 5:30 am
DSM
-
GRU
36h 36m
2 stops
LATAM Airlines Logo
5:45 pm - 2:05 pm
GRU
-
DSM
22h 20m
2 stops
$1,048LATAM Airlines
Mon, Aug 17 - Mon, Aug 24
LATAM Airlines Logo
6:35 pm - 5:40 am
DSM
-
GRU
33h 05m
1 stop
LATAM Airlines Logo
5:45 pm - 10:43 am
GRU
-
DSM
18h 58m
2 stops
$1,060LATAM Airlines
Mon, Aug 17 - Mon, Aug 24
LATAM Airlines Logo
6:35 pm - 5:40 am
DSM
-
GRU
33h 05m
1 stop
LATAM Airlines Logo
5:45 pm - 10:43 am
GRU
-
DSM
18h 58m
2 stops
$1,118LATAM Airlines
Mon, Aug 17 - Mon, Aug 24
Multiple Airlines Logo
9:33 am - 4:20 am
DSM
-
GRU
16h 47m
2 stops
Multiple Airlines Logo
10:50 pm - 2:05 pm
GRU
-
DSM
17h 15m
1 stop
$1,130Multiple Airlines
Sun, Aug 16 - Sun, Aug 23
LATAM Airlines Logo
6:54 pm - 5:30 am
DSM
-
GRU
32h 36m
2 stops
LATAM Airlines Logo
8:45 pm - 10:46 am
GRU
-
DSM
40h 01m
2 stops
$1,260LATAM Airlines
Sun, Sep 13 - Sun, Sep 20
LATAM Airlines Logo
6:54 pm - 5:40 am
DSM
-
GRU
32h 46m
1 stop
LATAM Airlines Logo
8:45 pm - 10:46 am
GRU
-
DSM
40h 01m
2 stops
$1,267LATAM Airlines
Sun, Sep 13 - Sun, Sep 20

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LATAM Airlines flights from Des Moines to Sao Paulo

Our best LATAM Airlines deals on Des Moines to Sao Paulo flight tickets
LATAM Airlines
Aug 17
DSM6:35 pmDes Moines
32h 25m
2 stops
GRU5:00 amSao Paulo Guarulhos Intl
Aug 24
GRU5:45 pmSao Paulo Guarulhos Intl
26h 05m
2 stops
DSM5:50 pmDes Moines
$1,003
LATAM Airlines
Aug 12
DSM6:35 pmDes Moines
33h 05m
1 stop
GRU5:40 amSao Paulo Guarulhos Intl
Aug 19
GRU8:45 pmSao Paulo Guarulhos Intl
39h 58m
2 stops
DSM10:43 amDes Moines
$1,030
LATAM Airlines
Aug 19
DSM6:35 pmDes Moines
32h 25m
2 stops
GRU5:00 amSao Paulo Guarulhos Intl
Aug 26
GRU1:05 pmSao Paulo Guarulhos Intl
30h 45m
2 stops
DSM5:50 pmDes Moines
$1,046

United Airlines flights from Des Moines to Sao Paulo

Our best United Airlines deals on Des Moines to Sao Paulo flight tickets
United Airlines
Nov 26
DSM8:00 amDes Moines
22h 30m
1 stop
GRU9:30 amSao Paulo Guarulhos Intl
Nov 29
GRU9:30 pmSao Paulo Guarulhos Intl
18h 06m
1 stop
DSM12:36 pmDes Moines
$1,363
United Airlines
Dec 13
DSM8:15 pmDes Moines
31h 55m
2 stops
GRU7:10 amSao Paulo Guarulhos Intl
Dec 19
GRU10:25 pmSao Paulo Guarulhos Intl
22h 08m
2 stops
DSM5:33 pmDes Moines
$1,367
United Airlines
Aug 19
DSM3:02 pmDes Moines
13h 28m
1 stop
GRU6:30 amSao Paulo Guarulhos Intl
Aug 26
GRU9:00 pmSao Paulo Guarulhos Intl
17h 20m
2 stops
DSM12:20 pmDes Moines
$1,437

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Sao Paulo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 7, 2026.
Use the filters below to find and compare flights from Des Moines to Sao Paulo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Mon 8/17

6:35 pm-5:00 am

2 stops32h 25m

Sao Paulo Guarulhos Intl

Mon 8/24

5:45 pm-5:50 pm

2 stops26h 05m

$1,003

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Wed 8/12

6:35 pm-5:40 am

1 stop33h 05m

Sao Paulo Guarulhos Intl

Wed 8/19

8:45 pm-10:43 am

2 stops39h 58m

$1,030

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Wed 8/19

6:35 pm-5:00 am

2 stops32h 25m

Sao Paulo Guarulhos Intl

Wed 8/26

1:05 pm-5:50 pm

2 stops30h 45m

$1,046

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Wed 8/12

6:35 pm-5:00 am

2 stops32h 25m

Sao Paulo Guarulhos Intl

Wed 8/19

8:45 pm-10:43 am

2 stops39h 58m

$1,047

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Mon 8/17

2:54 pm-5:30 am

2 stops36h 36m

Sao Paulo Guarulhos Intl

Mon 8/24

5:45 pm-2:05 pm

2 stops22h 20m

$1,048

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Mon 8/17

6:35 pm-5:40 am

1 stop33h 05m

Sao Paulo Guarulhos Intl

Mon 8/24

5:45 pm-10:43 am

2 stops18h 58m

$1,060

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Mon 8/17

6:35 pm-5:40 am

1 stop33h 05m

Sao Paulo Guarulhos Intl

Mon 8/24

5:45 pm-10:43 am

2 stops18h 58m

$1,118
Quickest round-trip

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sun 8/16

9:33 am-4:20 am

2 stops16h 47m

Sao Paulo Guarulhos Intl

Sun 8/23

10:50 pm-2:05 pm

1 stop17h 15m

$1,130

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sun 9/13

6:54 pm-5:30 am

2 stops32h 36m

Sao Paulo Guarulhos Intl

Sun 9/20

8:45 pm-10:46 am

2 stops40h 01m

$1,260

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sun 9/13

6:54 pm-5:40 am

1 stop32h 46m

Sao Paulo Guarulhos Intl

Sun 9/20

8:45 pm-10:46 am

2 stops40h 01m

$1,267

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Sao Paulo from

How to get the cheapest flight ticket from Des Moines to Sao Paulo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Des Moines to Sao Paulo?

American Airlines, LATAM Airlines, and Copa Airlines are the most popular carriers operating from Des Moines to Sao Paulo

When to book flights from Des Moines to Sao Paulo

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Sao Paulo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Sao Paulo (DSM to SAO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Sao Paulo

Fastest flight time

15h 36m

Direct flights

None
The fastest flight from Des Moines to Sao Paulo takes 15h 36m
There are no direct flights from Des Moines to Sao Paulo. There are no popular flight routes from Des Moines to Sao Paulo.
Search flight deals

Frequently asked questions about flying from Des Moines to Sao Paulo

  • How far is Des Moines to Sao Paulo by plane?

    Des Moines and Sao Paulo are 5407.3 mi apart from one another. 15h 36m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to Sao Paulo?

    Prices for flights from Des Moines Airport to Sao Paulo were last updated today.

  • How old do you have to be to fly from Des Moines Airport to Sao Paulo?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Sao Paulo.

  • What documentation or ID do you need to fly to Sao Paulo?

    The necessary travel and health documents for your Sao Paulo trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Sao Paulo?

Book flights to Sao Paulo if you plan to visit one of these locations
Santos
Guarujá

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Sao Paulo?

It is quick and easy to find Des Moines to Sao Paulo flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Sao Paulo that suits you.

Can I find flights from Des Moines to Sao Paulo with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Sao Paulo from Des Moines with this policy.

How can momondo help me find flights from Des Moines to Sao Paulo?

momondo helps you find the best flight between Des Moines and Sao Paulo by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Sao Paulo right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Sao Paulo, momondo offers a useful price alert feature which will track prices for flights to Sao Paulo from Des Moines and alert you when they change.

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Find better results for your trip to Brazil

Fly into one of these airports located in Sao Paulo

Airports listed have a maximum distance of 48.9 mi from Sao Paulo
Sao Paulo Congonhas Airport
Sao Paulo Guarulhos Intl Airport
Sao Paulo Viracopos Airport