Cheap flights from Tampa to San Diego from $79

If you are unable to visit San Diego during the month of January, then departing from Tampa during the month April is also very affordable. Most momondo users find prices during this month for around $321.

The cheapest day to depart from Tampa to San Diego is on a Wednesday. Travelers who choose to depart for San Diego on a Wednesday will often find tickets for as low as $308. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $452. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

The cheapest time of day to fly to San Diego is in the afternoon when flights can be purchased for as low as $360. Flights in the evening are often more expensive with an average ticket price of $380.

Fly from Tampa to San Diego for the best Tampa - San Diego flight prices

You are more likely to see cheaper flights to San Diego from Tampa when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $346 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Tampa for as low as $294 on momondo.

There are 4 cabin classes available to choose from on Tampa to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 9% on your flight if you consider stops on a Tampa to San Diego flight.

As of August 2026, prices for Tampa to San Diego flights are approximately 5% more expensive when compared to flights at the same time last year.

Southwest and Alaska Airlines are the most popular carriers operating from Tampa to San Diego

Alaska Airlines, Southwest and American Airlines are the top three most popular airlines that fly to San Diego from Tampa according to our data. Alaska Airlines is the first choice among our users, with 39% of people opting to fly with this airline when traveling to San Diego. Keep in mind that there are 9 different airlines that fly to San Diego on a routine basis, so you have a few additional options to choose from.

2 flights are operational daily from Tampa to San Diego as of August 2026. The most popular departure time for this route is 5:00PM, with 41% of flights per day taking off in the afternoon.

14 flights are operational weekly from Tampa to San Diego as of August 2026. The most popular departure day for this route is Mon, with 21% of flights per week taking off on this day.