Cheap flights from Pittsburgh to San Diego from $108

If you are unable to visit San Diego during the month of August, then departing from Pittsburgh during the month September is also very affordable. Most momondo users find prices during this month for around $276.

The cheapest day to depart from Pittsburgh to San Diego is on a Friday. Travelers who choose to depart for San Diego on a Friday will often find tickets for as low as $278. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $418. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

The cheapest time of day to fly to San Diego is in the morning when flights can be purchased for as low as $291. Flights in the afternoon are often more expensive with an average ticket price of $457.

Fly from Pittsburgh to San Diego for the best Pittsburgh - San Diego flight prices

You are more likely to see cheaper flights to San Diego from Pittsburgh when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $328 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Pittsburgh for as low as $265 on momondo.

There is only 1 cabin class available to choose from on Pittsburgh to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

No. A direct flight is the cheapest option for a flight between Pittsburgh to San Diego.

As of February 2026, prices for Pittsburgh to San Diego flights are approximately 53% more expensive when compared to flights at the same time last year.

American Airlines and United Airlines are the most popular carriers operating from Pittsburgh to San Diego

American Airlines, Southwest and United Airlines are the top three most popular airlines that fly to San Diego from Pittsburgh according to our data. American Airlines is the first choice among our users, with 34% of people opting to fly with this airline when traveling to San Diego. Keep in mind that there are 6 different airlines that fly to San Diego on a routine basis, so you have a few additional options to choose from.

Chicago (ORD) was the most common stop: 33% of momondo users choosing 1-stop flights on this route connected there.

Flights via Charlotte (CLT) offer the lowest average round-trip price of $208.

Flights connecting via Charlotte (CLT) have the shortest average one-way travel time: 7h 04m.

Dallas (DFW) has the shortest average layover time for this route: 0h 40m.