Cheap flights from Pittsburgh to San Diego from $109

If you are unable to visit San Diego during the month of January, then departing from Pittsburgh during the month May is also very affordable. Most momondo users find prices during this month for around $341.

The cheapest day to depart from Pittsburgh to San Diego is on a Saturday. Travelers who choose to depart for San Diego on a Saturday will often find tickets for as low as $246. If your travel schedule is flexible, try to avoid departing on a Wednesday because tickets tend to average around $573. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

The cheapest time of day to fly to San Diego is in the morning when flights can be purchased for as low as $343. Flights at noon are often more expensive with an average ticket price of $511.

Fly from Pittsburgh to San Diego for the best Pittsburgh - San Diego flight prices

You are more likely to see cheaper flights to San Diego from Pittsburgh when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $373 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Pittsburgh for as low as $297 on momondo.

There are 2 cabin classes available to choose from on Pittsburgh to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 10% on your flight if you consider stops on a Pittsburgh to San Diego flight.

As of November 2026, prices for Pittsburgh to San Diego flights are approximately 43% more expensive when compared to flights at the same time last year.

United Airlines, Southwest, and Delta are the most popular carriers operating from Pittsburgh to San Diego

Southwest, American Airlines and United Airlines are the top three most popular airlines that fly to San Diego from Pittsburgh according to our data. Southwest is the first choice among our users, with 38% of people opting to fly with this airline when traveling to San Diego. Keep in mind that there are 6 different airlines that fly to San Diego on a routine basis, so you have a few additional options to choose from.

Chicago (ORD) was the most common stop: 25% of momondo users choosing 1-stop flights on this route connected there.

Flights via Charlotte (CLT) offer the lowest average round-trip price of $310.

Flights connecting via Detroit (DTW) have the shortest average one-way travel time: 6h 49m.

Las Vegas (LAS) has the shortest average layover time for this route: 0h 45m.