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Cheap flights from Panama City, Florida to San Diego from $189

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to San Diego departing on 3/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Panama City, Florida to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
3:00 pm - 9:43 pm
ECP
-
SAN
8h 43m
1 stop
American Airlines Logo
8:00 am - 10:30 pm
SAN
-
ECP
12h 30m
1 stop
$367American Airlines
Sun, Feb 15 - Sat, Feb 28
Southwest Logo
7:35 am - 6:15 pm
ECP
-
SAN
12h 40m
1 stop
Southwest Logo
8:40 pm - 9:20 am
SAN
-
ECP
10h 40m
2 stops
$422Southwest
Sun, Feb 15 - Sat, Feb 28
Delta Logo
2:47 pm - 9:34 pm
ECP
-
SAN
8h 47m
1 stop
Delta Logo
9:40 pm - 8:17 am
SAN
-
ECP
8h 37m
1 stop
$462Delta
Sun, Jun 7 - Mon, Jun 29
United Airlines Logo
1:01 pm - 6:33 pm
ECP
-
SAN
7h 32m
1 stop
United Airlines Logo
10:30 am - 7:51 pm
SAN
-
ECP
7h 21m
1 stop
$471United Airlines
Sat, Feb 14 - Wed, Feb 18
United Airlines Logo
1:01 pm - 8:51 pm
ECP
-
SAN
9h 50m
2 stops
United Airlines Logo
12:16 pm - 7:51 pm
SAN
-
ECP
5h 35m
1 stop
$476United Airlines
Sat, Feb 14 - Wed, Feb 18
United Airlines Logo
1:01 pm - 11:40 pm
ECP
-
SAN
12h 39m
2 stops
United Airlines Logo
11:05 am - 9:56 pm
SAN
-
ECP
8h 51m
2 stops
$478United Airlines
Sun, Feb 15 - Sat, Feb 28
United Airlines Logo
1:10 pm - 6:36 pm
ECP
-
SAN
7h 26m
1 stop
United Airlines Logo
8:00 am - 4:12 pm
SAN
-
ECP
6h 12m
1 stop
$557United Airlines
Tue, Jan 27 - Sat, Jan 31
United Airlines Logo
6:30 am - 5:29 pm
ECP
-
SAN
12h 59m
2 stops
United Airlines Logo
6:30 am - 7:51 pm
SAN
-
ECP
11h 21m
2 stops
$561United Airlines
Sat, Feb 14 - Wed, Feb 18
United Airlines Logo
1:10 pm - 12:15 am
ECP
-
SAN
13h 05m
2 stops
United Airlines Logo
8:00 am - 4:12 pm
SAN
-
ECP
6h 12m
1 stop
$562United Airlines
Tue, Jan 27 - Sat, Jan 31
United Airlines Logo
1:10 pm - 12:15 am
ECP
-
SAN
13h 05m
2 stops
United Airlines Logo
7:52 pm - 12:02 pm
SAN
-
ECP
14h 10m
2 stops
$568United Airlines
Tue, Jan 27 - Sat, Jan 31

Delta flights from Panama City, Florida to San Diego

Our best Delta deals on Panama City, Florida to San Diego flight tickets
Delta
Jun 7
ECP2:47 pmPanama City NW Florida Beaches
8h 47m
1 stop
SAN9:34 pmSan Diego
Jun 29
SAN9:40 pmSan Diego
8h 37m
1 stop
ECP8:17 amPanama City NW Florida Beaches
$462
Delta
Jun 7
ECP3:20 pmPanama City NW Florida Beaches
9h 35m
2 stops
SAN10:55 pmSan Diego
Jun 29
SAN10:30 pmSan Diego
13h 22m
2 stops
ECP1:52 pmPanama City NW Florida Beaches
$2,557

United Airlines flights from Panama City, Florida to San Diego

Our best United Airlines deals on Panama City, Florida to San Diego flight tickets
United Airlines
Feb 14
ECP1:01 pmPanama City NW Florida Beaches
7h 32m
1 stop
SAN6:33 pmSan Diego
Feb 18
SAN10:30 amSan Diego
7h 21m
1 stop
ECP7:51 pmPanama City NW Florida Beaches
$471
United Airlines
Feb 14
ECP1:01 pmPanama City NW Florida Beaches
9h 50m
2 stops
SAN8:51 pmSan Diego
Feb 18
SAN12:16 pmSan Diego
5h 35m
1 stop
ECP7:51 pmPanama City NW Florida Beaches
$476
United Airlines
Feb 15
ECP1:01 pmPanama City NW Florida Beaches
12h 39m
2 stops
SAN11:40 pmSan Diego
Feb 28
SAN11:05 amSan Diego
8h 51m
2 stops
ECP9:56 pmPanama City NW Florida Beaches
$478

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 12, 2026.
Use the filters below to find and compare flights from Panama City, Florida to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Sun 2/15

3:00 pm-9:43 pm

1 stop8h 43m

San Diego

Sat 2/28

8:00 am-10:30 pm

1 stop12h 30m

$367

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Sun 2/15

7:35 am-6:15 pm

1 stop12h 40m

San Diego

Sat 2/28

8:40 pm-9:20 am

2 stops10h 40m

$422

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Sun 6/7

2:47 pm-9:34 pm

1 stop8h 47m

San Diego

Mon 6/29

9:40 pm-8:17 am

1 stop8h 37m

$462

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Sat 2/14

1:01 pm-6:33 pm

1 stop7h 32m

San Diego

Wed 2/18

10:30 am-7:51 pm

1 stop7h 21m

$471

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Sat 2/14

1:01 pm-8:51 pm

2 stops9h 50m

San Diego

Wed 2/18

12:16 pm-7:51 pm

1 stop5h 35m

$476

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Sun 2/15

1:01 pm-11:40 pm

2 stops12h 39m

San Diego

Sat 2/28

11:05 am-9:56 pm

2 stops8h 51m

$478

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Tue 1/27

1:10 pm-6:36 pm

1 stop7h 26m

San Diego

Sat 1/31

8:00 am-4:12 pm

1 stop6h 12m

$557

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Sat 2/14

6:30 am-5:29 pm

2 stops12h 59m

San Diego

Wed 2/18

6:30 am-7:51 pm

2 stops11h 21m

$561

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Tue 1/27

1:10 pm-12:15 am

2 stops13h 05m

San Diego

Sat 1/31

8:00 am-4:12 pm

1 stop6h 12m

$562

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Tue 1/27

1:10 pm-12:15 am

2 stops13h 05m

San Diego

Sat 1/31

7:52 pm-12:02 pm

2 stops14h 10m

$568

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Panama City, Florida to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of May, then departing from Panama City, Florida during the month October is also very affordable. Most momondo users find prices during this month for around $347.

How have Panama City, Florida to San Diego flight prices changed over time?

As of January 2026, prices for Panama City, Florida to San Diego flights are approximately 3% cheaper when compared to flights at the same time last year.

When to book flights from Panama City, Florida to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City, Florida to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City, Florida to San Diego (ECP to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to San Diego

Fastest flight time

5h 55m

Direct flights

None
The fastest flight from Panama City, Florida to San Diego takes 5h 55m
There are no direct flights from Panama City, Florida to San Diego. There are no popular flight routes from Panama City, Florida to San Diego.
Search flight deals

  • How far is Panama City NW Florida Beaches to San Diego by plane?

    San Diego is 1857.1 mi away from Panama City NW Florida Beaches. By plane, this route typically takes 5h 55m.

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to San Diego Airport?

    Prices for flights from Panama City NW Florida Beaches Airport to San Diego Airport are updated daily.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to San Diego Airport?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to San Diego Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Panama City, Florida to San Diego?

Best airlines flying from Panama City, Florida to San Diego

Compare and see reviews for airlines that fly from Panama City, Florida to San Diego with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $256Free CancellationRating
7.4
9,149 reviews
Search United Airlines flights
DeltaPriceFrom $260Free CancellationRating
7.9
8,039 reviews
Search Delta flights
SouthwestPriceFrom $260Free CancellationRating
8.0
4,256 reviews
Search Southwest flights
American AirlinesPriceFrom $306Free CancellationRating
7.2
11,114 reviews
Search American Airlines flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
Poway
National City
Imperial Beach
Borrego Springs
San Ysidro
La Mesa
Alpine
Lemon Grove
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to San Diego?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Diego from Panama City.

Can I find flights from Panama City to San Diego with flexible booking policies on momondo?

Yes. All flights to San Diego from Panama City on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Panama City to San Diego?

momondo provides multiple filters to help you find the best flight to San Diego from Panama City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama City to San Diego right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to San Diego flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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