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Cheap flights from Panama City, Florida to San Diego from $156

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to San Diego departing on 4/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Panama City, Florida to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
2:14 pm - 10:34 pm
ECP
-
SAN
10h 20m
1 stop
United Airlines Logo
10:40 pm - 9:53 am
SAN
-
ECP
9h 13m
1 stop
$295United Airlines
Tue, May 5 - Sat, May 9
United Airlines Logo
2:14 pm - 11:59 pm
ECP
-
SAN
11h 45m
2 stops
United Airlines Logo
12:10 pm - 10:05 pm
SAN
-
ECP
7h 55m
1 stop
$300United Airlines
Thu, Apr 30 - Tue, May 5
United Airlines Logo
2:14 pm - 11:59 pm
ECP
-
SAN
11h 45m
2 stops
United Airlines Logo
11:00 am - 10:05 pm
SAN
-
ECP
9h 05m
2 stops
$305United Airlines
Thu, Apr 30 - Tue, May 5
Southwest Logo
5:00 pm - 11:10 pm
ECP
-
SAN
8h 10m
1 stop
Southwest Logo
9:35 am - 5:45 pm
SAN
-
ECP
6h 10m
1 stop
$319Southwest
Thu, Apr 30 - Tue, May 5
Southwest Logo
7:55 am - 2:20 pm
ECP
-
SAN
8h 25m
2 stops
Southwest Logo
8:40 am - 8:25 pm
SAN
-
ECP
9h 45m
2 stops
$330Southwest
Tue, May 5 - Sat, May 9
United Airlines Logo
6:30 am - 2:57 pm
ECP
-
SAN
10h 27m
2 stops
United Airlines Logo
10:30 pm - 9:48 am
SAN
-
ECP
9h 18m
1 stop
$358United Airlines
Sat, Apr 11 - Mon, Apr 13
United Airlines Logo
6:30 am - 1:51 pm
ECP
-
SAN
9h 21m
1 stop
United Airlines Logo
10:30 pm - 9:48 am
SAN
-
ECP
9h 18m
1 stop
$365United Airlines
Sat, Apr 11 - Mon, Apr 13
United Airlines Logo
4:57 pm - 9:26 pm
ECP
-
SAN
6h 29m
1 stop
United Airlines Logo
10:30 pm - 9:38 am
SAN
-
ECP
9h 08m
1 stop
$385United Airlines
Thu, Apr 9 - Wed, Apr 22
United Airlines Logo
4:57 pm - 9:26 pm
ECP
-
SAN
6h 29m
1 stop
United Airlines Logo
7:40 pm - 9:38 am
SAN
-
ECP
11h 58m
2 stops
$390United Airlines
Thu, Apr 9 - Wed, Apr 22
United Airlines Logo
6:30 am - 2:57 pm
ECP
-
SAN
10h 27m
2 stops
United Airlines Logo
11:01 am - 9:59 pm
SAN
-
ECP
8h 58m
2 stops
$406United Airlines
Sat, Apr 11 - Mon, Apr 13

United Airlines flights from Panama City, Florida to San Diego

Our best United Airlines deals on Panama City, Florida to San Diego flight tickets
United Airlines
May 5
ECP2:14 pmPanama City NW Florida Beaches
10h 20m
1 stop
SAN10:34 pmSan Diego
May 9
SAN10:40 pmSan Diego
9h 13m
1 stop
ECP9:53 amPanama City NW Florida Beaches
$295
United Airlines
Apr 30
ECP2:14 pmPanama City NW Florida Beaches
11h 45m
2 stops
SAN11:59 pmSan Diego
May 5
SAN12:10 pmSan Diego
7h 55m
1 stop
ECP10:05 pmPanama City NW Florida Beaches
$300
United Airlines
Apr 30
ECP2:14 pmPanama City NW Florida Beaches
11h 45m
2 stops
SAN11:59 pmSan Diego
May 5
SAN11:00 amSan Diego
9h 05m
2 stops
ECP10:05 pmPanama City NW Florida Beaches
$305

Southwest flights from Panama City, Florida to San Diego

Our best Southwest deals on Panama City, Florida to San Diego flight tickets
Southwest
Apr 30
ECP5:00 pmPanama City NW Florida Beaches
8h 10m
1 stop
SAN11:10 pmSan Diego
May 5
SAN9:35 amSan Diego
6h 10m
1 stop
ECP5:45 pmPanama City NW Florida Beaches
$319
Southwest
May 5
ECP7:55 amPanama City NW Florida Beaches
8h 25m
2 stops
SAN2:20 pmSan Diego
May 9
SAN8:40 amSan Diego
9h 45m
2 stops
ECP8:25 pmPanama City NW Florida Beaches
$330
Southwest
Jul 31
ECP12:00 pmPanama City NW Florida Beaches
9h 15m
1 stop
SAN7:15 pmSan Diego
Aug 4
SAN7:30 amSan Diego
8h 40m
1 stop
ECP6:10 pmPanama City NW Florida Beaches
$407

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 27, 2026.
Use the filters below to find and compare flights from Panama City, Florida to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Tue 5/5

2:14 pm-10:34 pm

1 stop10h 20m

San Diego

Sat 5/9

10:40 pm-9:53 am

1 stop9h 13m

$295

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Thu 4/30

2:14 pm-11:59 pm

2 stops11h 45m

San Diego

Tue 5/5

12:10 pm-10:05 pm

1 stop7h 55m

$300

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Thu 4/30

2:14 pm-11:59 pm

2 stops11h 45m

San Diego

Tue 5/5

11:00 am-10:05 pm

2 stops9h 05m

$305

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Thu 4/30

5:00 pm-11:10 pm

1 stop8h 10m

San Diego

Tue 5/5

9:35 am-5:45 pm

1 stop6h 10m

$319

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Tue 5/5

7:55 am-2:20 pm

2 stops8h 25m

San Diego

Sat 5/9

8:40 am-8:25 pm

2 stops9h 45m

$330

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Sat 4/11

6:30 am-2:57 pm

2 stops10h 27m

San Diego

Mon 4/13

10:30 pm-9:48 am

1 stop9h 18m

$358

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Sat 4/11

6:30 am-1:51 pm

1 stop9h 21m

San Diego

Mon 4/13

10:30 pm-9:48 am

1 stop9h 18m

$365

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Thu 4/9

4:57 pm-9:26 pm

1 stop6h 29m

San Diego

Wed 4/22

10:30 pm-9:38 am

1 stop9h 08m

$385

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Thu 4/9

4:57 pm-9:26 pm

1 stop6h 29m

San Diego

Wed 4/22

7:40 pm-9:38 am

2 stops11h 58m

$390

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Sat 4/11

6:30 am-2:57 pm

2 stops10h 27m

San Diego

Mon 4/13

11:01 am-9:59 pm

2 stops8h 58m

$406

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Panama City, Florida to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of May, then departing from Panama City, Florida during the month October is also very affordable. Most momondo users find prices during this month for around $347.

How have Panama City, Florida to San Diego flight prices changed over time?

As of February 2026, prices for Panama City, Florida to San Diego flights are approximately 8% cheaper when compared to flights at the same time last year.

When to book flights from Panama City, Florida to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City, Florida to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City, Florida to San Diego (ECP to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to San Diego

Fastest flight time

6h 29m

Direct flights

None
The fastest flight from Panama City, Florida to San Diego takes 6h 29m
There are no direct flights from Panama City, Florida to San Diego. There are no popular flight routes from Panama City, Florida to San Diego.
Search flight deals

  • How far is Panama City NW Florida Beaches to San Diego by plane?

    San Diego is 1857.1 mi away from Panama City NW Florida Beaches. By plane, this route typically takes 6h 29m.

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to San Diego Airport?

    Prices for flights from Panama City NW Florida Beaches Airport to San Diego Airport are updated daily.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to San Diego Airport?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to San Diego Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Panama City, Florida to San Diego?

Best airlines flying from Panama City, Florida to San Diego

Compare and see reviews for airlines that fly from Panama City, Florida to San Diego with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $209Free CancellationRating
7.9
8,242 reviews
Search Delta flights
United AirlinesPriceFrom $256Free CancellationRating
7.4
9,349 reviews
Search United Airlines flights
SouthwestPriceFrom $260Free CancellationRating
8.0
4,301 reviews
Search Southwest flights
American AirlinesPriceFrom $306Free CancellationRating
7.2
11,357 reviews
Search American Airlines flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
Poway
National City
Imperial Beach
San Ysidro
Borrego Springs
La Mesa
Alpine
Lemon Grove
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to San Diego?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Diego from Panama City.

Can I find flights from Panama City to San Diego with flexible booking policies on momondo?

Yes. All flights to San Diego from Panama City on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Panama City to San Diego?

momondo provides multiple filters to help you find the best flight to San Diego from Panama City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama City to San Diego right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to San Diego flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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