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Cheap flights from Panama City, Florida to San Diego from $180

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to San Diego departing on 12/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Panama City, Florida to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
1:32 pm - 9:18 pmECP-SAN
9h 46m1 stop
Delta Logo
10:30 pm - 9:14 amSAN-ECP
8h 44m1 stop
$359Delta
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Tue, Dec 9 - Tue, Dec 16
Delta Logo
4:26 pm - 9:18 pmECP-SAN
6h 52m1 stop
Delta Logo
12:24 pm - 10:37 pmSAN-ECP
8h 13m1 stop
$369Delta
Find Deal
Mon, Dec 8 - Tue, Dec 16
United Airlines Logo
11:05 am - 8:48 pmECP-SAN
11h 43m2 stops
United Airlines Logo
1:53 pm - 9:49 pmSAN-ECP
5h 56m1 stop
$374United Airlines
Find Deal
Wed, Dec 10 - Mon, Dec 15
Delta Logo
7:30 am - 3:21 pmECP-SAN
9h 51m1 stop
Delta Logo
4:04 pm - 1:05 pmSAN-ECP
19h 01m2 stops
$376Delta
Find Deal
Tue, Dec 9 - Tue, Dec 16
Delta Logo
4:26 pm - 9:18 pmECP-SAN
6h 52m1 stop
Delta Logo
10:30 pm - 9:14 amSAN-ECP
8h 44m1 stop
$379Delta
Find Deal
Mon, Dec 8 - Sat, Dec 13
United Airlines Logo
5:00 pm - 11:42 pmECP-SAN
8h 42m2 stops
United Airlines Logo
1:53 pm - 9:49 pmSAN-ECP
5h 56m1 stop
$403United Airlines
Find Deal
Thu, Dec 4 - Sun, Dec 7
Southwest Logo
10:00 am - 5:05 pmECP-SAN
9h 05m2 stops
Southwest Logo
7:45 am - 5:35 pmSAN-ECP
7h 50m2 stops
$418Southwest
Find Deal
Thu, Dec 4 - Sun, Dec 7
American Airlines Logo
8:21 am - 4:10 pmECP-SAN
9h 49m1 stop
American Airlines Logo
9:54 pm - 7:52 amSAN-ECP
7h 58m1 stop
$424American Airlines
Find Deal
Mon, Nov 24 - Fri, Nov 28
Southwest Logo
9:50 am - 5:20 pmECP-SAN
9h 30m2 stops
Southwest Logo
6:20 am - 2:40 pmSAN-ECP
6h 20m1 stop
$433Southwest
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Wed, Nov 26 - Wed, Dec 3
American Airlines Logo
2:37 pm - 9:52 pmECP-SAN
9h 15m2 stops
American Airlines Logo
10:47 am - 11:10 pmSAN-ECP
10h 23m2 stops
$438American Airlines
Find Deal
Wed, Nov 26 - Wed, Dec 3

Delta flights from Panama City, Florida to San Diego

Our best Delta deals on Panama City, Florida to San Diego flight tickets
Delta
Dec 9
ECP1:32 pmPanama City NW Florida Beaches
9h 46m
1 stop
SAN9:18 pmSan Diego
Dec 16
SAN10:30 pmSan Diego
8h 44m
1 stop
ECP9:14 amPanama City NW Florida Beaches
$359
Find similar
Delta
Dec 8
ECP4:26 pmPanama City NW Florida Beaches
6h 52m
1 stop
SAN9:18 pmSan Diego
Dec 16
SAN12:24 pmSan Diego
8h 13m
1 stop
ECP10:37 pmPanama City NW Florida Beaches
$369
Find similar
Delta
Dec 9
ECP7:30 amPanama City NW Florida Beaches
9h 51m
1 stop
SAN3:21 pmSan Diego
Dec 16
SAN4:04 pmSan Diego
19h 01m
2 stops
ECP1:05 pmPanama City NW Florida Beaches
$376
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United Airlines flights from Panama City, Florida to San Diego

Our best United Airlines deals on Panama City, Florida to San Diego flight tickets
United Airlines
Dec 10
ECP11:05 amPanama City NW Florida Beaches
11h 43m
2 stops
SAN8:48 pmSan Diego
Dec 15
SAN1:53 pmSan Diego
5h 56m
1 stop
ECP9:49 pmPanama City NW Florida Beaches
$374
Find similar
United Airlines
Dec 4
ECP5:00 pmPanama City NW Florida Beaches
8h 42m
2 stops
SAN11:42 pmSan Diego
Dec 7
SAN1:53 pmSan Diego
5h 56m
1 stop
ECP9:49 pmPanama City NW Florida Beaches
$403
Find similar
United Airlines
Nov 24
ECP5:00 pmPanama City NW Florida Beaches
6h 53m
1 stop
SAN9:53 pmSan Diego
Nov 28
SAN8:40 pmSan Diego
10h 39m
2 stops
ECP9:19 amPanama City NW Florida Beaches
$429
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 4, 2025.
Use the filters below to find and compare flights from Panama City, Florida to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Tue 12/9

1:32 pm-9:18 pm

1 stop9h 46m

San Diego

Tue 12/16

10:30 pm-9:14 am

1 stop8h 44m

$359

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Mon 12/8

4:26 pm-9:18 pm

1 stop6h 52m

San Diego

Tue 12/16

12:24 pm-10:37 pm

1 stop8h 13m

$369

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Wed 12/10

11:05 am-8:48 pm

2 stops11h 43m

San Diego

Mon 12/15

1:53 pm-9:49 pm

1 stop5h 56m

$374

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Tue 12/9

7:30 am-3:21 pm

1 stop9h 51m

San Diego

Tue 12/16

4:04 pm-1:05 pm

2 stops19h 01m

$376

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Mon 12/8

4:26 pm-9:18 pm

1 stop6h 52m

San Diego

Sat 12/13

10:30 pm-9:14 am

1 stop8h 44m

$379

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Thu 12/4

5:00 pm-11:42 pm

2 stops8h 42m

San Diego

Sun 12/7

1:53 pm-9:49 pm

1 stop5h 56m

$403

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Thu 12/4

10:00 am-5:05 pm

2 stops9h 05m

San Diego

Sun 12/7

7:45 am-5:35 pm

2 stops7h 50m

$418

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Mon 11/24

8:21 am-4:10 pm

1 stop9h 49m

San Diego

Fri 11/28

9:54 pm-7:52 am

1 stop7h 58m

$424

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Wed 11/26

9:50 am-5:20 pm

2 stops9h 30m

San Diego

Wed 12/3

6:20 am-2:40 pm

1 stop6h 20m

$433

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Wed 11/26

2:37 pm-9:52 pm

2 stops9h 15m

San Diego

Wed 12/3

10:47 am-11:10 pm

2 stops10h 23m

$438

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Panama City, Florida to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City, Florida and San Diego?

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of May, then departing from Panama City, Florida during the month October is also very affordable. Most momondo users find prices during this month for around $358.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Panama City, Florida to San Diego is on a Wednesday. Travelers who choose to depart for San Diego on a Wednesday will often find tickets for as low as $395. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $793. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

How have Panama City, Florida to San Diego flight prices changed over time?

As of November 2025, prices for Panama City, Florida to San Diego flights are approximately 28% more expensive when compared to flights at the same time last year.

When to book flights from Panama City, Florida to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City, Florida to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City, Florida to San Diego (ECP to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to San Diego

Direct flights

None
There are no direct flights from Panama City, Florida to San Diego. There are no popular flight routes from Panama City, Florida to San Diego.
Search flight deals

  • How far is Panama City NW Florida Beaches to San Diego by plane?

    San Diego is 1857.1 mi away from Panama City NW Florida Beaches. By plane, this route typically takes 6h 46m.

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to San Diego Airport?

    Prices for flights from Panama City NW Florida Beaches Airport to San Diego Airport are updated daily.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to San Diego Airport?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to San Diego Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Panama City, Florida to San Diego?

Best airlines flying from Panama City, Florida to San Diego

Compare and see reviews for airlines that fly from Panama City, Florida to San Diego with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $296Free CancellationRating
7.9
8,003 reviews
Search Delta flights
SouthwestPriceFrom $316Free CancellationRating
8.0
4,239 reviews
Search Southwest flights
American AirlinesPriceFrom $326Free CancellationRating
7.2
11,040 reviews
Search American Airlines flights
United AirlinesPriceFrom $354Free CancellationRating
7.4
9,002 reviews
Search United Airlines flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
Imperial Beach
La Mesa
Poway
Borrego Springs
San Ysidro
Lemon Grove
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to San Diego?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Diego from Panama City.

Can I find flights from Panama City to San Diego with flexible booking policies on momondo?

Yes. All flights to San Diego from Panama City on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Panama City to San Diego?

momondo provides multiple filters to help you find the best flight to San Diego from Panama City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama City to San Diego right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to San Diego flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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