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Cheap flights from Panama City, Florida to San Diego from $163

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to San Diego departing on 8/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Panama City, Florida to San Diego

Cheap round-trip flights

American Airlines Logo
6:32 am - 12:03 pmECP-SAN
7h 31m1 stop
American Airlines Logo
11:30 am - 9:12 pmSAN-ECP
7h 42m1 stop
$325American Airlines
Find Deal
Tue, Sep 9 - Sat, Sep 13
American Airlines Logo
6:32 am - 3:21 pmECP-SAN
10h 49m2 stops
American Airlines Logo
10:32 pm - 9:42 amSAN-ECP
9h 10m1 stop
$330American Airlines
Find Deal
Tue, Sep 9 - Sat, Sep 13
American Airlines Logo
5:25 pm - 11:52 pmECP-SAN
8h 27m1 stop
American Airlines Logo
7:15 am - 6:14 pmSAN-ECP
8h 59m1 stop
$332American Airlines
Find Deal
Fri, Aug 29 - Sun, Aug 31
American Airlines Logo
6:32 am - 3:21 pmECP-SAN
10h 49m2 stops
American Airlines Logo
9:45 am - 9:12 pmSAN-ECP
9h 27m2 stops
$335American Airlines
Find Deal
Tue, Sep 9 - Sat, Sep 13
Delta Logo
1:53 pm - 7:26 pmECP-SAN
7h 33m1 stop
Delta Logo
10:47 am - 7:48 pmSAN-ECP
7h 01m1 stop
$351Delta
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Tue, Aug 19 - Fri, Aug 22
Delta Logo
6:54 pm - 11:24 pmECP-SAN
6h 30m1 stop
Delta Logo
10:55 am - 7:30 pmSAN-ECP
6h 35m1 stop
$371Delta
Find Deal
Sun, Sep 28 - Wed, Oct 1
Southwest Logo
10:40 am - 7:50 pmECP-SAN
11h 10m2 stops
Southwest Logo
9:05 am - 7:55 pmSAN-ECP
8h 50m2 stops
$423Southwest
Find Deal
Fri, Aug 29 - Sun, Aug 31
United Airlines Logo
5:02 pm - 11:44 pmECP-SAN
8h 42m2 stops
United Airlines Logo
8:00 am - 8:16 pmSAN-ECP
10h 16m2 stops
$435United Airlines
Find Deal
Fri, Aug 15 - Tue, Aug 19
United Airlines Logo
6:30 am - 1:40 pmECP-SAN
9h 10m2 stops
United Airlines Logo
6:15 am - 4:20 pmSAN-ECP
8h 05m1 stop
$438United Airlines
Find Deal
Thu, Aug 28 - Mon, Sep 1
Southwest Logo
6:15 pm - 9:55 pmECP-SAN
5h 40m1 stop
Southwest Logo
8:30 am - 8:05 pmSAN-ECP
9h 35m2 stops
$463Southwest
Find Deal
Sun, Sep 28 - Wed, Oct 1

Southwest flights from Panama City, Florida to San Diego

Our best Southwest deals on Panama City, Florida to San Diego flight tickets
Southwest
Aug 29
ECP10:40 amPanama City NW Florida Beaches
11h 10m
2 stops
SAN7:50 pmSan Diego
Aug 31
SAN9:05 amSan Diego
8h 50m
2 stops
ECP7:55 pmPanama City NW Florida Beaches
$423
Find similar
Southwest
Sep 28
ECP6:15 pmPanama City NW Florida Beaches
5h 40m
1 stop
SAN9:55 pmSan Diego
Oct 1
SAN8:30 amSan Diego
9h 35m
2 stops
ECP8:05 pmPanama City NW Florida Beaches
$463
Find similar
Southwest
Sep 28
ECP4:35 pmPanama City NW Florida Beaches
8h 30m
2 stops
SAN11:05 pmSan Diego
Oct 1
SAN8:30 amSan Diego
9h 35m
2 stops
ECP8:05 pmPanama City NW Florida Beaches
$557
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Delta flights from Panama City, Florida to San Diego

Our best Delta deals on Panama City, Florida to San Diego flight tickets
Delta
Aug 19
ECP1:53 pmPanama City NW Florida Beaches
7h 33m
1 stop
SAN7:26 pmSan Diego
Aug 22
SAN10:47 amSan Diego
7h 01m
1 stop
ECP7:48 pmPanama City NW Florida Beaches
$351
Find similar
Delta
Sep 28
ECP6:54 pmPanama City NW Florida Beaches
6h 30m
1 stop
SAN11:24 pmSan Diego
Oct 1
SAN10:55 amSan Diego
6h 35m
1 stop
ECP7:30 pmPanama City NW Florida Beaches
$371
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momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Panama City, Florida to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Tue 9/9

6:32 am-12:03 pm

1 stop7h 31m

San Diego

Sat 9/13

11:30 am-9:12 pm

1 stop7h 42m

$325

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Tue 9/9

6:32 am-3:21 pm

2 stops10h 49m

San Diego

Sat 9/13

10:32 pm-9:42 am

1 stop9h 10m

$330

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Fri 8/29

5:25 pm-11:52 pm

1 stop8h 27m

San Diego

Sun 8/31

7:15 am-6:14 pm

1 stop8h 59m

$332

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Tue 9/9

6:32 am-3:21 pm

2 stops10h 49m

San Diego

Sat 9/13

9:45 am-9:12 pm

2 stops9h 27m

$335

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Tue 8/19

1:53 pm-7:26 pm

1 stop7h 33m

San Diego

Fri 8/22

10:47 am-7:48 pm

1 stop7h 01m

$351

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Sun 9/28

6:54 pm-11:24 pm

1 stop6h 30m

San Diego

Wed 10/1

10:55 am-7:30 pm

1 stop6h 35m

$371

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Fri 8/29

10:40 am-7:50 pm

2 stops11h 10m

San Diego

Sun 8/31

9:05 am-7:55 pm

2 stops8h 50m

$423

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Fri 8/15

5:02 pm-11:44 pm

2 stops8h 42m

San Diego

Tue 8/19

8:00 am-8:16 pm

2 stops10h 16m

$435

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Thu 8/28

6:30 am-1:40 pm

2 stops9h 10m

San Diego

Mon 9/1

6:15 am-4:20 pm

1 stop8h 05m

$438

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Sun 9/28

6:15 pm-9:55 pm

1 stop5h 40m

San Diego

Wed 10/1

8:30 am-8:05 pm

2 stops9h 35m

$463

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Panama City, Florida to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of September, then departing from Panama City, Florida during the month May is also very affordable. Most momondo users find prices during this month for around $358.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Panama City, Florida to San Diego is on a Wednesday. Travelers who choose to depart for San Diego on a Wednesday will often find tickets for as low as $395. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $793. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

How have Panama City, Florida to San Diego flight prices changed over time?

As of July 2025, prices for Panama City, Florida to San Diego flights are approximately 22% cheaper when compared to flights at the same time last year.

When to book flights from Panama City, Florida to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City, Florida to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City, Florida to San Diego (ECP to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to San Diego

Best Price Found

$163

Fastest flight time

5h 40m

Direct flights

None

Airports in San Diego

1 airport
The best one-way flight to San Diego from Panama City, Florida in the past 72 hours is $163. The best round-trip flight deal from Panama City, Florida to San Diego found on momondo in the last 72 hours is $325.
The fastest flight from Panama City, Florida to San Diego takes 5h 40m
There are no direct flights from Panama City, Florida to San Diego. Popular non-direct route for this connection is Panama City NW Florida Beaches Airport - San Diego Airport.
There is 1 airport near San Diego: San Diego (SAN)
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  • How far is Panama City NW Florida Beaches to San Diego by plane?

    San Diego is 1857.1 mi away from Panama City NW Florida Beaches. By plane, this route typically takes 5h 40m.

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to San Diego Airport?

    Prices for flights from Panama City NW Florida Beaches Airport to San Diego Airport are updated daily.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to San Diego Airport?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to San Diego Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Panama City, Florida to San Diego?

Best airlines flying from Panama City, Florida to San Diego

Compare and see reviews for airlines that fly from Panama City, Florida to San Diego with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $296Free CancellationRating
8.0
7,981 reviews
Search Delta flights
SouthwestPriceFrom $326Free CancellationRating
8.0
4,246 reviews
Search Southwest flights
American AirlinesPriceFrom $348Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $386Free CancellationRating
7.4
8,900 reviews
Search United Airlines flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
La Mesa
Imperial Beach
San Ysidro
Poway
Borrego Springs
Lemon Grove
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to San Diego?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Diego from Panama City.

Can I find flights from Panama City to San Diego with flexible booking policies on momondo?

Yes. All flights to San Diego from Panama City on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Panama City to San Diego?

momondo provides multiple filters to help you find the best flight to San Diego from Panama City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama City to San Diego right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to San Diego flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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