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Cheap flights from Panama City, Florida to San Diego from $174

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to San Diego departing on 9/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Panama City, Florida to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
5:15 pm - 9:05 pmECP  Panama City NW Florida Beaches-SAN San Diego
5h 50m1 stop Houston Hobby
Southwest Logo
6:20 am - 3:20 pmSAN  San Diego-ECP Panama City NW Florida Beaches
7h 00m1 stop Houston Hobby
$259Southwest
Sat, Sep 5 - Fri, Sep 11
Southwest Logo
3:40 pm - 11:15 pmECP  Panama City NW Florida Beaches-SAN San Diego
9h 35m2 stops Nashville Intl Denver Intl
Southwest Logo
6:20 am - 3:20 pmSAN  San Diego-ECP Panama City NW Florida Beaches
7h 00m1 stop Houston Hobby
$264Southwest
Sat, Sep 5 - Fri, Sep 11
Southwest Logo
3:40 pm - 11:15 pmECP  Panama City NW Florida Beaches-SAN San Diego
9h 35m2 stops Nashville Intl Denver Intl
Southwest Logo
10:40 pm - 1:55 pmSAN  San Diego-ECP Panama City NW Florida Beaches
13h 15m2 stops Chicago Midway Baltimore/Washington
$275Southwest
Sat, Sep 5 - Fri, Sep 11
Delta Logo
5:02 pm - 11:00 pmECP  Panama City NW Florida Beaches-SAN San Diego
7h 58m1 stop Atlanta Hartsfield-Jackson
Delta Logo
12:52 pm - 11:05 pmSAN  San Diego-ECP Panama City NW Florida Beaches
8h 13m1 stop Atlanta Hartsfield-Jackson
$311Delta
Sat, Sep 5 - Fri, Sep 11
Delta Logo
11:31 am - 3:51 pmECP  Panama City NW Florida Beaches-SAN San Diego
6h 20m1 stop Atlanta Hartsfield-Jackson
Delta Logo
2:00 pm - 11:05 pmSAN  San Diego-ECP Panama City NW Florida Beaches
7h 05m1 stop Atlanta Hartsfield-Jackson
$311Delta
Sat, Sep 5 - Fri, Sep 11
United Airlines Logo
6:30 am - 10:55 amECP  Panama City NW Florida Beaches-SAN San Diego
6h 25m1 stop Houston George Bush Intcntl
United Airlines Logo
7:41 pm - 11:04 amSAN  San Diego-ECP Panama City NW Florida Beaches
13h 23m2 stops San Francisco Houston George Bush Intcntl
$334United Airlines
Sun, Sep 6 - Sat, Sep 12
Delta Logo
5:26 pm - 11:00 pmECP  Panama City NW Florida Beaches-SAN San Diego
7h 34m1 stop Atlanta Hartsfield-Jackson
Delta Logo
2:00 pm - 11:05 pmSAN  San Diego-ECP Panama City NW Florida Beaches
7h 05m1 stop Atlanta Hartsfield-Jackson
$347Delta
Thu, Sep 3 - Thu, Sep 10
American Airlines Logo
3:00 pm - 9:03 pmECP  Panama City NW Florida Beaches-SAN San Diego
8h 03m1 stop Dallas/Fort Worth
American Airlines Logo
11:15 am - 9:07 pmSAN  San Diego-ECP Panama City NW Florida Beaches
7h 52m1 stop Dallas/Fort Worth
$359American Airlines
Fri, Sep 4 - Fri, Sep 11
American Airlines Logo
3:17 pm - 9:48 pmECP  Panama City NW Florida Beaches-SAN San Diego
8h 31m1 stop Dallas/Fort Worth
American Airlines Logo
10:27 pm - 10:24 amSAN  San Diego-ECP Panama City NW Florida Beaches
9h 57m1 stop Charlotte Douglas
$373American Airlines
Tue, Sep 15 - Sat, Sep 19
United Airlines Logo
6:30 am - 3:54 pmECP  Panama City NW Florida Beaches-SAN San Diego
11h 24m2 stops Houston George Bush Intcntl San Francisco
United Airlines Logo
6:20 am - 4:38 pmSAN  San Diego-ECP Panama City NW Florida Beaches
8h 18m2 stops Los Angeles Los Angeles Houston George Bush Intcntl
$447United Airlines
Mon, Aug 24 - Fri, Aug 28

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American Airlines flights from Panama City, Florida to San Diego

Our best American Airlines deals on Panama City, Florida to San Diego flight tickets
American Airlines
Sep 15
ECP3:17 pmPanama City NW Florida Beaches
8h 31m
1 stop
SAN9:48 pmSan Diego
Sep 19
SAN10:27 pmSan Diego
9h 57m
1 stop
ECP10:24 amPanama City NW Florida Beaches
$373
American Airlines
Dec 4
ECP11:11 amPanama City NW Florida Beaches
9h 39m
1 stop
SAN6:50 pmSan Diego
Dec 7
SAN6:15 amSan Diego
6h 30m
1 stop
ECP2:45 pmPanama City NW Florida Beaches
$377
American Airlines
Sep 3
ECP6:03 pmPanama City NW Florida Beaches
6h 27m
1 stop
SAN10:30 pmSan Diego
Sep 7
SAN10:45 pmSan Diego
13h 45m
1 stop
ECP2:30 pmPanama City NW Florida Beaches
$414

Southwest flights from Panama City, Florida to San Diego

Our best Southwest deals on Panama City, Florida to San Diego flight tickets
Southwest
Sep 5
ECP5:15 pmPanama City NW Florida Beaches
5h 50m
1 stop
SAN9:05 pmSan Diego
Sep 11
SAN6:20 amSan Diego
7h 00m
1 stop
ECP3:20 pmPanama City NW Florida Beaches
$259
Southwest
Sep 5
ECP3:40 pmPanama City NW Florida Beaches
9h 35m
2 stops
SAN11:15 pmSan Diego
Sep 11
SAN6:20 amSan Diego
7h 00m
1 stop
ECP3:20 pmPanama City NW Florida Beaches
$264
Southwest
Sep 5
ECP3:40 pmPanama City NW Florida Beaches
9h 35m
2 stops
SAN11:15 pmSan Diego
Sep 11
SAN10:40 pmSan Diego
13h 15m
2 stops
ECP1:55 pmPanama City NW Florida Beaches
$275

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 10, 2026.
Use the filters below to find and compare flights from Panama City, Florida to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Panama CitySan Diego

ECP Panama City NW Florida Beaches - SAN San Diego

ECPSAN

Panama City NW Florida Beaches

Sat 9/5

5:15 pm-9:05 pm

1 stop5h 50m

San Diego

Fri 9/11

6:20 am-3:20 pm

1 stop7h 00m

$259

Panama CitySan Diego

ECP Panama City NW Florida Beaches - SAN San Diego

ECPSAN

Panama City NW Florida Beaches

Sat 9/5

3:40 pm-11:15 pm

2 stops9h 35m

San Diego

Fri 9/11

6:20 am-3:20 pm

1 stop7h 00m

$264

Panama CitySan Diego

ECP Panama City NW Florida Beaches - SAN San Diego

ECPSAN

Panama City NW Florida Beaches

Sat 9/5

3:40 pm-11:15 pm

2 stops9h 35m

San Diego

Fri 9/11

10:40 pm-1:55 pm

2 stops13h 15m

$275

Panama CitySan Diego

ECP Panama City NW Florida Beaches - SAN San Diego

ECPSAN

Panama City NW Florida Beaches

Sat 9/5

5:02 pm-11:00 pm

1 stop7h 58m

San Diego

Fri 9/11

12:52 pm-11:05 pm

1 stop8h 13m

$311

Panama CitySan Diego

ECP Panama City NW Florida Beaches - SAN San Diego

ECPSAN

Panama City NW Florida Beaches

Sat 9/5

11:31 am-3:51 pm

1 stop6h 20m

San Diego

Fri 9/11

2:00 pm-11:05 pm

1 stop7h 05m

$311

Panama CitySan Diego

ECP Panama City NW Florida Beaches - SAN San Diego

ECPSAN

Panama City NW Florida Beaches

Sun 9/6

6:30 am-10:55 am

1 stop6h 25m

San Diego

Sat 9/12

7:41 pm-11:04 am

2 stops13h 23m

$334

Panama CitySan Diego

ECP Panama City NW Florida Beaches - SAN San Diego

ECPSAN

Panama City NW Florida Beaches

Thu 9/3

5:26 pm-11:00 pm

1 stop7h 34m

San Diego

Thu 9/10

2:00 pm-11:05 pm

1 stop7h 05m

$347

Panama CitySan Diego

ECP Panama City NW Florida Beaches - SAN San Diego

ECPSAN

Panama City NW Florida Beaches

Fri 9/4

3:00 pm-9:03 pm

1 stop8h 03m

San Diego

Fri 9/11

11:15 am-9:07 pm

1 stop7h 52m

$359

Panama CitySan Diego

ECP Panama City NW Florida Beaches - SAN San Diego

ECPSAN

Panama City NW Florida Beaches

Tue 9/15

3:17 pm-9:48 pm

1 stop8h 31m

San Diego

Sat 9/19

10:27 pm-10:24 am

1 stop9h 57m

$373

Panama CitySan Diego

ECP Panama City NW Florida Beaches - SAN San Diego

ECPSAN

Panama City NW Florida Beaches

Mon 8/24

6:30 am-3:54 pm

2 stops11h 24m

San Diego

Fri 8/28

6:20 am-4:38 pm

2 stops8h 18m

$447

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Panama City, Florida to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City, Florida and San Diego?

Prices are currently low for flights on this route.

Typical prices usually range from $457 to $733.
The lowest price recently found on this route was $259.

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of October, then departing from Panama City, Florida during the month September is also very affordable. Most momondo users find prices during this month for around $366.

How have Panama City, Florida to San Diego flight prices changed over time?

When to book flights from Panama City, Florida to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City, Florida to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City, Florida to San Diego (ECP to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to San Diego

Fastest flight time

5h 50m

Direct flights

None
The fastest flight from Panama City, Florida to San Diego takes 5h 50m
There are no direct flights from Panama City, Florida to San Diego. There are no popular flight routes from Panama City, Florida to San Diego.
Search flight deals

Frequently asked questions about flying from Panama City, Florida to San Diego

  • How far is Panama City NW Florida Beaches to San Diego by plane?

    San Diego is 1857.1 mi away from Panama City NW Florida Beaches. By plane, this route typically takes 5h 50m.

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to San Diego Airport?

    Prices for flights from Panama City NW Florida Beaches Airport to San Diego Airport are updated daily.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to San Diego Airport?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to San Diego Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Panama City, Florida to San Diego?

Best airlines flying from Panama City, Florida to San Diego

Compare and see reviews for airlines that fly from Panama City, Florida to San Diego with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $256Free CancellationRating
7.4
10,095 reviews
Search United Airlines flights
DeltaPriceFrom $260Free CancellationRating
7.8
8,497 reviews
Search Delta flights
American AirlinesPriceFrom $326Free CancellationRating
7.1
11,897 reviews
Search American Airlines flights
SouthwestPriceFrom $384Free CancellationRating
8.0
4,218 reviews
Search Southwest flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Chula Vista
Coronado
El Cajon
National City
Julian
La Mesa
Poway
San Ysidro
Imperial Beach
Santee
Borrego Springs
Lemon Grove
Alpine

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to San Diego?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Diego from Panama City.

Can I find flights from Panama City to San Diego with flexible booking policies on momondo?

Yes. All flights to San Diego from Panama City on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Panama City to San Diego?

momondo provides multiple filters to help you find the best flight to San Diego from Panama City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama City to San Diego right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to San Diego flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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