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Cheap flights from Chicago Midway Airport to Los Angeles from $108

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago Midway Airport to Los Angeles departing on 9/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Chicago Midway Airport to Los Angeles

Cheap round-trip flights

Logo
6:24 pm - 1:35 pmMDW-SNA
21h 11m1 stop
Logo
8:09 pm - 11:13 amSNA-MDW
13h 04m2 stops
$257
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Fri, Oct 17 - Sun, Oct 19
Frontier Logo
6:24 pm - 1:35 pmMDW-SNA
21h 11m1 stop
Frontier Logo
7:52 pm - 9:46 pmSNA-MDW
23h 54m1 stop
$258Frontier
Find Deal
Fri, Oct 17 - Sun, Oct 19
Logo
12:11 pm - 7:14 pmMDW-SNA
33h 03m2 stops
Logo
2:20 pm - 12:30 pmSNA-MDW
20h 10m1 stop
$264
Find Deal
Fri, Oct 24 - Sat, Nov 1
Frontier Logo
6:24 pm - 11:16 amMDW-SNA
18h 52m1 stop
Frontier Logo
12:01 pm - 12:24 amSNA-MDW
10h 23m1 stop
$265Frontier
Find Deal
Thu, Oct 23 - Mon, Oct 27
Delta Logo
6:00 am - 11:16 amMDW-SNA
7h 16m1 stop
Delta Logo
12:26 pm - 10:14 pmSNA-MDW
7h 48m1 stop
$269Delta
Find Deal
Wed, Oct 29 - Sat, Nov 1
Frontier Logo
4:48 pm - 12:13 pmMDW-SNA
21h 25m1 stop
Frontier Logo
11:52 am - 3:53 pmSNA-MDW
26h 01m1 stop
$271Frontier
Find Deal
Fri, Oct 3 - Sun, Oct 5
Delta Logo
1:05 pm - 6:39 pmMDW-SNA
7h 34m1 stop
Delta Logo
8:00 am - 6:07 pmSNA-MDW
8h 07m1 stop
$274Delta
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Tue, Nov 18 - Fri, Nov 28
Southwest Logo
11:15 am - 5:30 pmMDW-SNA
8h 15m1 stop
Southwest Logo
7:35 pm - 5:15 amSNA-MDW
7h 40m1 stop
$277Southwest
Find Deal
Tue, Oct 7 - Tue, Oct 14
Southwest Logo
6:40 am - 11:20 amMDW-SNA
6h 40m1 stop
Southwest Logo
7:00 am - 5:45 pmSNA-MDW
8h 45m2 stops
$282Southwest
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Wed, Sep 24 - Wed, Oct 1
Southwest Logo
5:15 pm - 9:15 pmMDW-SNA
6h 00m1 stop
Southwest Logo
6:45 am - 5:10 pmSNA-MDW
8h 25m1 stop
$283Southwest
Find Deal
Thu, Dec 4 - Wed, Dec 10

Southwest flights from Chicago Midway Airport to Santa Ana

Our best Southwest deals on Chicago Midway Airport to Santa Ana flight tickets
Southwest
Oct 7
MDW11:15 amChicago Midway
8h 15m
1 stop
SNA5:30 pmSanta Ana J. Wayne/Orange Cnty
Oct 14
SNA7:35 pmSanta Ana J. Wayne/Orange Cnty
7h 40m
1 stop
MDW5:15 amChicago Midway
$277
Find similar
Southwest
Sep 24
MDW6:40 amChicago Midway
6h 40m
1 stop
SNA11:20 amSanta Ana J. Wayne/Orange Cnty
Oct 1
SNA7:00 amSanta Ana J. Wayne/Orange Cnty
8h 45m
2 stops
MDW5:45 pmChicago Midway
$282
Find similar
Southwest
Dec 4
MDW5:15 pmChicago Midway
6h 00m
1 stop
SNA9:15 pmSanta Ana J. Wayne/Orange Cnty
Dec 10
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
8h 25m
1 stop
MDW5:10 pmChicago Midway
$283
Find similar

Delta flights from Chicago Midway Airport to Santa Ana

Our best Delta deals on Chicago Midway Airport to Santa Ana flight tickets
Delta
Oct 29
MDW6:00 amChicago Midway
7h 16m
1 stop
SNA11:16 amSanta Ana J. Wayne/Orange Cnty
Nov 1
SNA12:26 pmSanta Ana J. Wayne/Orange Cnty
7h 48m
1 stop
MDW10:14 pmChicago Midway
$269
Find similar
Delta
Nov 18
MDW1:05 pmChicago Midway
7h 34m
1 stop
SNA6:39 pmSanta Ana J. Wayne/Orange Cnty
Nov 28
SNA8:00 amSanta Ana J. Wayne/Orange Cnty
8h 07m
1 stop
MDW6:07 pmChicago Midway
$274
Find similar
Delta
Sep 4
MDW6:00 amChicago Midway
8h 42m
1 stop
SNA12:42 pmSanta Ana J. Wayne/Orange Cnty
Sep 9
SNA12:03 pmSanta Ana J. Wayne/Orange Cnty
7h 23m
1 stop
MDW9:26 pmChicago Midway
$299
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Chicago Midway Airport to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 21, 2025.
Use the filters below to find and compare flights from Chicago Midway Airport to Santa Ana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Fri 10/17

6:24 pm-1:35 pm

1 stop21h 11m

Santa Ana J. Wayne/Orange Cnty

Sun 10/19

8:09 pm-11:13 am

2 stops13h 04m

$257

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Fri 10/17

6:24 pm-1:35 pm

1 stop21h 11m

Santa Ana J. Wayne/Orange Cnty

Sun 10/19

7:52 pm-9:46 pm

1 stop23h 54m

$258

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Fri 10/24

12:11 pm-7:14 pm

2 stops33h 03m

Santa Ana J. Wayne/Orange Cnty

Sat 11/1

2:20 pm-12:30 pm

1 stop20h 10m

$264

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Thu 10/23

6:24 pm-11:16 am

1 stop18h 52m

Santa Ana J. Wayne/Orange Cnty

Mon 10/27

12:01 pm-12:24 am

1 stop10h 23m

$265

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Wed 10/29

6:00 am-11:16 am

1 stop7h 16m

Santa Ana J. Wayne/Orange Cnty

Sat 11/1

12:26 pm-10:14 pm

1 stop7h 48m

$269

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Fri 10/3

4:48 pm-12:13 pm

1 stop21h 25m

Santa Ana J. Wayne/Orange Cnty

Sun 10/5

11:52 am-3:53 pm

1 stop26h 01m

$271

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Tue 11/18

1:05 pm-6:39 pm

1 stop7h 34m

Santa Ana J. Wayne/Orange Cnty

Fri 11/28

8:00 am-6:07 pm

1 stop8h 07m

$274

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Tue 10/7

11:15 am-5:30 pm

1 stop8h 15m

Santa Ana J. Wayne/Orange Cnty

Tue 10/14

7:35 pm-5:15 am

1 stop7h 40m

$277

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Wed 9/24

6:40 am-11:20 am

1 stop6h 40m

Santa Ana J. Wayne/Orange Cnty

Wed 10/1

7:00 am-5:45 pm

2 stops8h 45m

$282

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Thu 12/4

5:15 pm-9:15 pm

1 stop6h 00m

Santa Ana J. Wayne/Orange Cnty

Wed 12/10

6:45 am-5:10 pm

1 stop8h 25m

$283

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Los Angeles from

How to get the cheapest flight ticket from Chicago Midway Airport to Santa Ana

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana?

The cheapest month to fly to Santa Ana from Chicago Midway Airport is in November. Flight prices, which tend to average around $274, are often lower during this time because this is during the off-season. The month of August is another great option to travel to Santa Ana, with average flight prices from Chicago Midway Airport averaging around $288.

What is the cheapest day to depart on your flight to Santa Ana?

On average, the least expensive day to fly to Santa Ana from Chicago Midway Airport is on a Saturday. momondo users have found tickets for Saturday departures for as low as $367. However, this price may fluctuate depending on the airline, the season, and holidays. On the other hand, Sunday is the most expensive day to depart from Chicago Midway Airport because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $473.

What is the cheapest time of day to depart on your flight to Santa Ana?

Our data shows that the cheapest Chicago Midway Airport to Santa Ana flights are usually those with departure times in the morning. Our users have found flights to Santa Ana in the morning for as low as $380. Try not to purchase tickets in the evening because they tend to be around $452. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Chicago Midway Airport to Santa Ana

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago Midway Airport to Santa Ana according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago Midway Airport to Santa Ana (MDW to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago Midway Airport to Santa Ana

Direct flights

None
There are no direct flights from Chicago Midway Airport to Santa Ana. There are no popular flight routes from Chicago Midway Airport to Santa Ana.
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  • How far is Chicago Midway to Santa Ana J. Wayne/Orange Cnty by plane?

    Santa Ana J. Wayne/Orange Cnty is 1724.9 mi away from Chicago Midway. 6h 00m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Chicago Midway Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Chicago Midway Airport to Santa Ana J. Wayne/Orange Cnty Airport are updated daily.

  • How many operators does momondo search for flights from Chicago Midway Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Chicago Midway Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Chicago Midway Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The travel and health documents you'll need for your trip to Santa Ana J. Wayne/Orange Cnty Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santa Ana J. Wayne/Orange Cnty Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Chicago Midway Airport to Santa Ana?

Best airlines flying from Chicago Midway Airport to Santa Ana

Compare and see reviews for airlines that fly from Chicago Midway Airport to Santa Ana with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $130Free CancellationRating
5.8
3,207 reviews
Search Frontier flights
SouthwestPriceFrom $288Free CancellationRating
8.0
4,245 reviews
Search Southwest flights

  • Southwest Flights From Chicago Midway Airport to Santa Ana

    Across 6 Southwest flights from Chicago Midway Airport to Santa Ana this week, the average price was $440, with the best Southwest deals starting from $288 round-trip. 4,245 users have rated Southwest on momondo, with an average score of 8.0/10.

Traveling to a place near Los Angeles?

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Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Santa Ana?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Santa Ana. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Santa Ana with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Chicago to Santa Ana flights to just show those with flexible booking policies.

How can momondo help me find flights from Chicago to Santa Ana?

Once you have performed a search for Chicago to Santa Ana flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Chicago to Santa Ana right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Santa Ana flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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