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Cheap flights from Chicago Midway Airport to Los Angeles from $145

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago Midway Airport to Los Angeles departing on 5/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Chicago Midway Airport to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
12:25 pm - 6:55 pm
MDW
-
SNA
8h 30m
1 stop
Southwest Logo
7:30 pm - 5:00 am
SNA
-
MDW
7h 30m
1 stop
$269Southwest
Tue, Mar 10 - Tue, Mar 17
Frontier Logo
6:15 am - 6:11 pm
MDW
-
SNA
13h 56m
2 stops
Frontier Logo
5:27 pm - 2:49 pm
SNA
-
MDW
19h 22m
1 stop
$270Frontier
Fri, Apr 24 - Sun, Apr 26
Frontier Logo
6:15 am - 8:50 am
MDW
-
SNA
28h 35m
1 stop
Frontier Logo
5:27 pm - 2:49 pm
SNA
-
MDW
19h 22m
1 stop
$273Frontier
Thu, Apr 23 - Sun, Apr 26
Southwest Logo
5:55 am - 12:10 pm
MDW
-
SNA
8h 15m
2 stops
Southwest Logo
8:00 pm - 5:00 am
SNA
-
MDW
7h 00m
1 stop
$274Southwest
Tue, Mar 10 - Tue, Mar 17
Frontier Logo
3:21 pm - 4:25 pm
MDW
-
SNA
27h 04m
1 stop
Frontier Logo
8:50 am - 8:21 pm
SNA
-
MDW
9h 31m
2 stops
$278Frontier
Sun, Mar 1 - Sat, Mar 7
Southwest Logo
10:05 am - 8:55 pm
MDW
-
SNA
12h 50m
2 stops
Southwest Logo
6:45 am - 5:40 pm
SNA
-
MDW
8h 55m
2 stops
$279Southwest
Tue, Apr 14 - Thu, Apr 16
Southwest Logo
10:10 am - 8:55 pm
MDW
-
SNA
12h 45m
3 stops
Southwest Logo
6:45 am - 5:40 pm
SNA
-
MDW
8h 55m
2 stops
$285Southwest
Tue, Apr 14 - Thu, Apr 16
Southwest Logo
8:05 am - 2:50 pm
MDW
-
SNA
8h 45m
1 stop
Southwest Logo
8:10 pm - 5:00 am
SNA
-
MDW
6h 50m
1 stop
$289Southwest
Mon, Mar 2 - Fri, Mar 6
Southwest Logo
5:00 am - 9:50 am
MDW
-
SNA
6h 50m
1 stop
Southwest Logo
8:45 pm - 5:45 am
SNA
-
MDW
7h 00m
1 stop
$293Southwest
Thu, Apr 2 - Mon, Apr 6
Southwest Logo
1:30 pm - 8:10 pm
MDW
-
SNA
8h 40m
1 stop
Southwest Logo
9:05 pm - 5:45 am
SNA
-
MDW
6h 40m
1 stop
$294Southwest
Sat, Feb 28 - Sun, Mar 8

Frontier flights from Chicago Midway Airport to Santa Ana

Our best Frontier deals on Chicago Midway Airport to Santa Ana flight tickets
Frontier
Apr 24
MDW6:15 amChicago Midway
13h 56m
2 stops
SNA6:11 pmSanta Ana J. Wayne/Orange Cnty
Apr 26
SNA5:27 pmSanta Ana J. Wayne/Orange Cnty
19h 22m
1 stop
MDW2:49 pmChicago Midway
$270
Frontier
Apr 23
MDW6:15 amChicago Midway
28h 35m
1 stop
SNA8:50 amSanta Ana J. Wayne/Orange Cnty
Apr 26
SNA5:27 pmSanta Ana J. Wayne/Orange Cnty
19h 22m
1 stop
MDW2:49 pmChicago Midway
$273
Frontier
Mar 1
MDW3:21 pmChicago Midway
27h 04m
1 stop
SNA4:25 pmSanta Ana J. Wayne/Orange Cnty
Mar 7
SNA8:50 amSanta Ana J. Wayne/Orange Cnty
9h 31m
2 stops
MDW8:21 pmChicago Midway
$278

Delta flights from Chicago Midway Airport to Santa Ana

Our best Delta deals on Chicago Midway Airport to Santa Ana flight tickets
Delta
Apr 13
MDW2:12 pmChicago Midway
8h 45m
1 stop
SNA8:57 pmSanta Ana J. Wayne/Orange Cnty
Apr 23
SNA8:00 amSanta Ana J. Wayne/Orange Cnty
8h 36m
1 stop
MDW6:36 pmChicago Midway
$334
Delta
Mar 24
MDW12:47 pmChicago Midway
8h 55m
1 stop
SNA7:42 pmSanta Ana J. Wayne/Orange Cnty
Mar 28
SNA8:00 amSanta Ana J. Wayne/Orange Cnty
8h 40m
1 stop
MDW6:40 pmChicago Midway
$354
Delta
Feb 20
MDW6:00 amChicago Midway
7h 49m
1 stop
SNA11:49 amSanta Ana J. Wayne/Orange Cnty
Feb 25
SNA12:04 pmSanta Ana J. Wayne/Orange Cnty
8h 27m
1 stop
MDW10:31 pmChicago Midway
$419

momondo Fare Finder

 
Customize your flight search to find flights from Chicago Midway Airport to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 10, 2026.
Use the filters below to find and compare flights from Chicago Midway Airport to Santa Ana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Tue 3/10

12:25 pm-6:55 pm

1 stop8h 30m

Santa Ana J. Wayne/Orange Cnty

Tue 3/17

7:30 pm-5:00 am

1 stop7h 30m

$269

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Fri 4/24

6:15 am-6:11 pm

2 stops13h 56m

Santa Ana J. Wayne/Orange Cnty

Sun 4/26

5:27 pm-2:49 pm

1 stop19h 22m

$270

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Thu 4/23

6:15 am-8:50 am

1 stop28h 35m

Santa Ana J. Wayne/Orange Cnty

Sun 4/26

5:27 pm-2:49 pm

1 stop19h 22m

$273

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Tue 3/10

5:55 am-12:10 pm

2 stops8h 15m

Santa Ana J. Wayne/Orange Cnty

Tue 3/17

8:00 pm-5:00 am

1 stop7h 00m

$274

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Sun 3/1

3:21 pm-4:25 pm

1 stop27h 04m

Santa Ana J. Wayne/Orange Cnty

Sat 3/7

8:50 am-8:21 pm

2 stops9h 31m

$278

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Tue 4/14

10:05 am-8:55 pm

2 stops12h 50m

Santa Ana J. Wayne/Orange Cnty

Thu 4/16

6:45 am-5:40 pm

2 stops8h 55m

$279

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Tue 4/14

10:10 am-8:55 pm

3 stops12h 45m

Santa Ana J. Wayne/Orange Cnty

Thu 4/16

6:45 am-5:40 pm

2 stops8h 55m

$285

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Mon 3/2

8:05 am-2:50 pm

1 stop8h 45m

Santa Ana J. Wayne/Orange Cnty

Fri 3/6

8:10 pm-5:00 am

1 stop6h 50m

$289

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Thu 4/2

5:00 am-9:50 am

1 stop6h 50m

Santa Ana J. Wayne/Orange Cnty

Mon 4/6

8:45 pm-5:45 am

1 stop7h 00m

$293

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Sat 2/28

1:30 pm-8:10 pm

1 stop8h 40m

Santa Ana J. Wayne/Orange Cnty

Sun 3/8

9:05 pm-5:45 am

1 stop6h 40m

$294

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Los Angeles from

How to get the cheapest flight ticket from Chicago Midway Airport to Santa Ana

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana?

The cheapest month to fly to Santa Ana from Chicago Midway Airport is in September. Flight prices, which tend to average around $279, are often lower during this time because this is during the off-season. The month of August is another great option to travel to Santa Ana, with average flight prices from Chicago Midway Airport averaging around $288.

What is the cheapest day to depart on your flight to Santa Ana?

On average, the least expensive day to fly to Santa Ana from Chicago Midway Airport is on a Saturday. momondo users have found tickets for Saturday departures for as low as $355. However, this price may fluctuate depending on the airline, the season, and holidays. On the other hand, Sunday is the most expensive day to depart from Chicago Midway Airport because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $456.

What is the cheapest time of day to depart on your flight to Santa Ana?

Our data shows that the cheapest Chicago Midway Airport to Santa Ana flights are usually those with departure times in the morning. Our users have found flights to Santa Ana in the morning for as low as $371. Try not to purchase tickets in the afternoon because they tend to be around $396. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Chicago Midway Airport to Santa Ana

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago Midway Airport to Santa Ana according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago Midway Airport to Santa Ana (MDW to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago Midway Airport to Santa Ana

Fastest flight time

6h 15m

Direct flights

None
The fastest flight from Chicago Midway Airport to Santa Ana takes 6h 15m
There are no direct flights from Chicago Midway Airport to Santa Ana. There are no popular flight routes from Chicago Midway Airport to Santa Ana.
Search flight deals

  • How far is Chicago Midway to Santa Ana J. Wayne/Orange Cnty by plane?

    Santa Ana J. Wayne/Orange Cnty is 1724.9 mi away from Chicago Midway. 6h 15m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Chicago Midway Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Chicago Midway Airport to Santa Ana J. Wayne/Orange Cnty Airport are updated daily.

  • How many operators does momondo search for flights from Chicago Midway Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Chicago Midway Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Chicago Midway Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The travel and health documents you'll need for your trip to Santa Ana J. Wayne/Orange Cnty Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santa Ana J. Wayne/Orange Cnty Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Chicago Midway Airport to Santa Ana?

Best airlines flying from Chicago Midway Airport to Santa Ana

Compare and see reviews for airlines that fly from Chicago Midway Airport to Santa Ana with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $288Free CancellationRating
8.0
4,280 reviews
Search Southwest flights

  • Southwest Flights From Chicago Midway Airport to Santa Ana

    Across 2 Southwest flights from Chicago Midway Airport to Santa Ana this week, the average price was $433, with the best Southwest deals starting from $288 round-trip. 4,280 users have rated Southwest on momondo, with an average score of 8.0/10.

Traveling to a place near Los Angeles?

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Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Santa Ana?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Santa Ana. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Santa Ana with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Chicago to Santa Ana flights to just show those with flexible booking policies.

How can momondo help me find flights from Chicago to Santa Ana?

Once you have performed a search for Chicago to Santa Ana flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Chicago to Santa Ana right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Santa Ana flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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