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Cheap flights from Chicago Midway Airport to Los Angeles from $160

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago Midway Airport to Los Angeles departing on 8/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Chicago Midway Airport to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
5:00 pm - 9:55 pm
MDW
-
SNA
6h 55m
2 stops
Southwest Logo
8:30 am - 5:10 pm
SNA
-
MDW
6h 40m
2 stops
$323Southwest
Fri, Aug 28 - Wed, Sep 2
Southwest Logo
10:10 am - 3:00 pm
MDW
-
SNA
6h 50m
2 stops
Southwest Logo
6:35 pm - 5:00 am
SNA
-
MDW
8h 25m
1 stop
$329Southwest
Wed, Aug 5 - Tue, Aug 11
Multiple Airlines Logo
8:20 pm - 12:12 pm
MDW
-
SNA
17h 52m
1 stop
Multiple Airlines Logo
2:27 pm - 9:51 am
SNA
-
MDW
17h 24m
2 stops
$336Multiple Airlines
Thu, Aug 6 - Mon, Aug 10
Southwest Logo
3:45 pm - 9:35 pm
MDW
-
SNA
7h 50m
2 stops
Southwest Logo
6:45 am - 4:05 pm
SNA
-
MDW
7h 20m
2 stops
$337Southwest
Fri, Oct 2 - Tue, Oct 6
Southwest Logo
5:00 pm - 9:55 pm
MDW
-
SNA
6h 55m
2 stops
Southwest Logo
8:30 am - 5:10 pm
SNA
-
MDW
6h 40m
2 stops
$341Southwest
Fri, Aug 21 - Wed, Aug 26
Multiple Airlines Logo
8:20 pm - 12:12 pm
MDW
-
SNA
17h 52m
1 stop
Multiple Airlines Logo
1:16 pm - 9:51 am
SNA
-
MDW
18h 35m
2 stops
$343Multiple Airlines
Thu, Aug 13 - Sat, Aug 15
Southwest Logo
7:10 am - 10:50 am
MDW
-
SNA
5h 40m
1 stop
Southwest Logo
8:45 pm - 5:45 am
SNA
-
MDW
7h 00m
1 stop
$344Southwest
Thu, Aug 13 - Sun, Aug 16
Southwest Logo
6:05 am - 11:35 am
MDW
-
SNA
7h 30m
1 stop
Southwest Logo
6:45 am - 4:20 pm
SNA
-
MDW
7h 35m
2 stops
$346Southwest
Fri, Oct 16 - Wed, Oct 21
Southwest Logo
6:50 am - 10:30 am
MDW
-
SNA
5h 40m
1 stop
Southwest Logo
8:45 pm - 5:40 am
SNA
-
MDW
6h 55m
1 stop
$347Southwest
Sat, Aug 29 - Thu, Sep 3
Southwest Logo
5:40 am - 10:50 am
MDW
-
SNA
7h 10m
1 stop
Southwest Logo
8:55 pm - 5:00 am
SNA
-
MDW
6h 05m
1 stop
$349Southwest
Thu, Aug 6 - Sun, Aug 9

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Southwest flights from Chicago Midway Airport to Santa Ana, California

Our best Southwest deals on Chicago Midway Airport to Santa Ana, California flight tickets
Southwest
Aug 28
MDW5:00 pmChicago Midway
6h 55m
2 stops
SNA9:55 pmSanta Ana J. Wayne/Orange Cnty
Sep 2
SNA8:30 amSanta Ana J. Wayne/Orange Cnty
6h 40m
2 stops
MDW5:10 pmChicago Midway
$323
Southwest
Aug 5
MDW10:10 amChicago Midway
6h 50m
2 stops
SNA3:00 pmSanta Ana J. Wayne/Orange Cnty
Aug 11
SNA6:35 pmSanta Ana J. Wayne/Orange Cnty
8h 25m
1 stop
MDW5:00 amChicago Midway
$329
Southwest
Oct 2
MDW3:45 pmChicago Midway
7h 50m
2 stops
SNA9:35 pmSanta Ana J. Wayne/Orange Cnty
Oct 6
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
7h 20m
2 stops
MDW4:05 pmChicago Midway
$337

Delta flights from Chicago Midway Airport to Santa Ana, California

Our best Delta deals on Chicago Midway Airport to Santa Ana, California flight tickets
Delta
Sep 18
MDW2:00 pmChicago Midway
8h 23m
1 stop
SNA8:23 pmSanta Ana J. Wayne/Orange Cnty
Sep 21
SNA7:09 pmSanta Ana J. Wayne/Orange Cnty
12h 41m
2 stops
MDW9:50 amChicago Midway
$354
Delta
Sep 4
MDW9:59 amChicago Midway
8h 15m
2 stops
SNA4:14 pmSanta Ana J. Wayne/Orange Cnty
Sep 8
SNA6:10 pmSanta Ana J. Wayne/Orange Cnty
12h 38m
2 stops
MDW8:48 amChicago Midway
$370
Delta
Nov 2
MDW1:28 pmChicago Midway
10h 37m
2 stops
SNA10:05 pmSanta Ana J. Wayne/Orange Cnty
Nov 11
SNA8:00 amSanta Ana J. Wayne/Orange Cnty
6h 50m
1 stop
MDW4:50 pmChicago Midway
$409

momondo Fare Finder

 
Customize your flight search to find flights from Chicago Midway Airport to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 9, 2026.
Use the filters below to find and compare flights from Chicago Midway Airport to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Fri 8/28

5:00 pm-9:55 pm

2 stops6h 55m

Santa Ana J. Wayne/Orange Cnty

Wed 9/2

8:30 am-5:10 pm

2 stops6h 40m

$323

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Wed 8/5

10:10 am-3:00 pm

2 stops6h 50m

Santa Ana J. Wayne/Orange Cnty

Tue 8/11

6:35 pm-5:00 am

1 stop8h 25m

$329

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Thu 8/6

8:20 pm-12:12 pm

1 stop17h 52m

Santa Ana J. Wayne/Orange Cnty

Mon 8/10

2:27 pm-9:51 am

2 stops17h 24m

$336

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Fri 10/2

3:45 pm-9:35 pm

2 stops7h 50m

Santa Ana J. Wayne/Orange Cnty

Tue 10/6

6:45 am-4:05 pm

2 stops7h 20m

$337

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Fri 8/21

5:00 pm-9:55 pm

2 stops6h 55m

Santa Ana J. Wayne/Orange Cnty

Wed 8/26

8:30 am-5:10 pm

2 stops6h 40m

$341

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Thu 8/13

8:20 pm-12:12 pm

1 stop17h 52m

Santa Ana J. Wayne/Orange Cnty

Sat 8/15

1:16 pm-9:51 am

2 stops18h 35m

$343

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Thu 8/13

7:10 am-10:50 am

1 stop5h 40m

Santa Ana J. Wayne/Orange Cnty

Sun 8/16

8:45 pm-5:45 am

1 stop7h 00m

$344

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Fri 10/16

6:05 am-11:35 am

1 stop7h 30m

Santa Ana J. Wayne/Orange Cnty

Wed 10/21

6:45 am-4:20 pm

2 stops7h 35m

$346
Quickest round-trip

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Sat 8/29

6:50 am-10:30 am

1 stop5h 40m

Santa Ana J. Wayne/Orange Cnty

Thu 9/3

8:45 pm-5:40 am

1 stop6h 55m

$347

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Thu 8/6

5:40 am-10:50 am

1 stop7h 10m

Santa Ana J. Wayne/Orange Cnty

Sun 8/9

8:55 pm-5:00 am

1 stop6h 05m

$349

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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2

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How to get the cheapest flight ticket from Chicago Midway Airport to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana, California?

In general, September is the cheapest month to fly from Chicago Midway Airport to Santa Ana, California. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $288. If you aren’t able to travel during the month of September, then book flights to Santa Ana, California from Chicago Midway Airport during August instead. Flights to Santa Ana, California in August, while not as cheap as those in September, still average around $288.

What is the cheapest day to depart on your flight to Santa Ana, California?

The cheapest day to depart from Chicago Midway Airport to Santa Ana, California is on a Saturday. Travelers who choose to depart for Santa Ana, California on a Saturday will often find tickets for as low as $387. The most expensive day to fly to Santa Ana, California is Sunday, with ticket prices averaging around $535.

What is the cheapest time of day to depart on your flight to Santa Ana, California?

In the morning is the cheapest time of day to fly from Chicago Midway Airport to Santa Ana, California when you can find flight prices for as low as $402. Flying to Santa Ana, California in the morning is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Santa Ana, California is in the evening when prices are around $439.

How have Chicago Midway Airport to Santa Ana, California flight prices changed over time?

When to book flights from Chicago Midway Airport to Santa Ana, California

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago Midway Airport to Santa Ana, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago Midway Airport to Santa Ana, California (MDW to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago Midway Airport to Santa Ana, California

Fastest flight time

5h 40m

Direct flights

None
The fastest flight from Chicago Midway Airport to Santa Ana, California takes 5h 40m
There are no direct flights from Chicago Midway Airport to Santa Ana, California. There are no popular flight routes from Chicago Midway Airport to Santa Ana, California.
Search flight deals

Frequently asked questions about flying from Chicago Midway Airport to Santa Ana, California

  • How far is Chicago Midway to Santa Ana J. Wayne/Orange Cnty by plane?

    Santa Ana J. Wayne/Orange Cnty is 1724.9 mi away from Chicago Midway. 5h 40m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Chicago Midway Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Chicago Midway Airport to Santa Ana J. Wayne/Orange Cnty Airport are updated daily.

  • How many operators does momondo search for flights from Chicago Midway Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Chicago Midway Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Chicago Midway Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The travel and health documents you'll need for your trip to Santa Ana J. Wayne/Orange Cnty Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santa Ana J. Wayne/Orange Cnty Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Chicago Midway Airport to Santa Ana, California?

Best airlines flying from Chicago Midway Airport to Santa Ana, California

Compare and see reviews for airlines that fly from Chicago Midway Airport to Santa Ana, California with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $288Free CancellationRating
7.9
4,248 reviews
Search Southwest flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Santa Ana?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Santa Ana. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Santa Ana with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Chicago to Santa Ana flights to just show those with flexible booking policies.

How can momondo help me find flights from Chicago to Santa Ana?

Once you have performed a search for Chicago to Santa Ana flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Chicago to Santa Ana right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Santa Ana flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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