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Cheap flights from Chicago Midway Airport to Los Angeles from $146

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago Midway Airport to Los Angeles departing on 5/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Chicago Midway Airport to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
3:40 pm - 9:10 pm
MDW
-
SNA
7h 30m
1 stop
Southwest Logo
9:10 pm - 5:00 am
SNA
-
MDW
5h 50m
1 stop
$301Southwest
Mon, Apr 13 - Thu, Apr 16
Multiple Airlines Logo
1:30 pm - 1:44 pm
MDW
-
SNA
26h 14m
1 stop
Multiple Airlines Logo
7:25 am - 9:55 pm
SNA
-
MDW
12h 30m
2 stops
$305Multiple Airlines
Fri, Apr 24 - Mon, Apr 27
Multiple Airlines Logo
6:20 am - 3:11 pm
MDW
-
SNA
10h 51m
1 stop
Multiple Airlines Logo
4:33 pm - 2:12 pm
SNA
-
MDW
19h 39m
2 stops
$311Multiple Airlines
Sun, May 3 - Tue, May 5
Frontier Logo
3:27 pm - 8:50 am
MDW
-
SNA
19h 23m
1 stop
Frontier Logo
5:01 pm - 10:19 pm
SNA
-
MDW
27h 18m
2 stops
$315Frontier
Thu, Apr 30 - Sun, May 3
Frontier Logo
3:27 pm - 8:50 am
MDW
-
SNA
19h 23m
1 stop
Frontier Logo
5:01 pm - 10:19 pm
SNA
-
MDW
27h 18m
2 stops
$316Frontier
Thu, Apr 30 - Sun, May 3
Southwest Logo
2:15 pm - 7:05 pm
MDW
-
SNA
6h 50m
1 stop
Southwest Logo
7:40 pm - 5:00 am
SNA
-
MDW
7h 20m
1 stop
$323Southwest
Wed, Apr 29 - Mon, May 4
Southwest Logo
6:10 am - 11:05 am
MDW
-
SNA
6h 55m
1 stop
Southwest Logo
8:30 am - 6:00 pm
SNA
-
MDW
7h 30m
2 stops
$328Southwest
Wed, Apr 29 - Mon, May 4
Southwest Logo
7:30 am - 2:00 pm
MDW
-
SNA
8h 30m
1 stop
Southwest Logo
6:10 pm - 5:40 am
SNA
-
MDW
9h 30m
1 stop
$329Southwest
Wed, May 27 - Sat, May 30
Frontier Logo
3:27 pm - 8:50 am
MDW
-
SNA
19h 23m
1 stop
Frontier Logo
5:01 pm - 3:04 pm
SNA
-
MDW
20h 03m
1 stop
$332Frontier
Thu, Apr 30 - Sun, May 3
Southwest Logo
10:10 am - 1:55 pm
MDW
-
SNA
5h 45m
1 stop
Southwest Logo
7:50 pm - 5:00 am
SNA
-
MDW
7h 10m
1 stop
$337Southwest
Tue, Apr 21 - Tue, Apr 28

Delta flights from Chicago Midway Airport to Santa Ana, California

Our best Delta deals on Chicago Midway Airport to Santa Ana, California flight tickets
Delta
May 20
MDW1:59 pmChicago Midway
8h 35m
1 stop
SNA8:34 pmSanta Ana J. Wayne/Orange Cnty
May 25
SNA8:00 amSanta Ana J. Wayne/Orange Cnty
7h 56m
1 stop
MDW5:56 pmChicago Midway
$343
Delta
May 27
MDW1:59 pmChicago Midway
8h 35m
1 stop
SNA8:34 pmSanta Ana J. Wayne/Orange Cnty
Jun 6
SNA8:00 amSanta Ana J. Wayne/Orange Cnty
7h 56m
1 stop
MDW5:56 pmChicago Midway
$374
Delta
May 20
MDW1:59 pmChicago Midway
8h 35m
1 stop
SNA8:34 pmSanta Ana J. Wayne/Orange Cnty
May 28
SNA8:00 amSanta Ana J. Wayne/Orange Cnty
7h 56m
1 stop
MDW5:56 pmChicago Midway
$408

Southwest flights from Chicago Midway Airport to Santa Ana, California

Our best Southwest deals on Chicago Midway Airport to Santa Ana, California flight tickets
Southwest
Apr 29
MDW2:15 pmChicago Midway
6h 50m
1 stop
SNA7:05 pmSanta Ana J. Wayne/Orange Cnty
May 4
SNA7:40 pmSanta Ana J. Wayne/Orange Cnty
7h 20m
1 stop
MDW5:00 amChicago Midway
$323
Southwest
Apr 29
MDW6:10 amChicago Midway
6h 55m
1 stop
SNA11:05 amSanta Ana J. Wayne/Orange Cnty
May 4
SNA8:30 amSanta Ana J. Wayne/Orange Cnty
7h 30m
2 stops
MDW6:00 pmChicago Midway
$328
Southwest
May 27
MDW7:30 amChicago Midway
8h 30m
1 stop
SNA2:00 pmSanta Ana J. Wayne/Orange Cnty
May 30
SNA6:10 pmSanta Ana J. Wayne/Orange Cnty
9h 30m
1 stop
MDW5:40 amChicago Midway
$329

momondo Fare Finder

 
Customize your flight search to find flights from Chicago Midway Airport to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 1, 2026.
Use the filters below to find and compare flights from Chicago Midway Airport to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Mon 4/13

3:40 pm-9:10 pm

1 stop7h 30m

Santa Ana J. Wayne/Orange Cnty

Thu 4/16

9:10 pm-5:00 am

1 stop5h 50m

$301

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Fri 4/24

1:30 pm-1:44 pm

1 stop26h 14m

Santa Ana J. Wayne/Orange Cnty

Mon 4/27

7:25 am-9:55 pm

2 stops12h 30m

$305

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Sun 5/3

6:20 am-3:11 pm

1 stop10h 51m

Santa Ana J. Wayne/Orange Cnty

Tue 5/5

4:33 pm-2:12 pm

2 stops19h 39m

$311

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Thu 4/30

3:27 pm-8:50 am

1 stop19h 23m

Santa Ana J. Wayne/Orange Cnty

Sun 5/3

5:01 pm-10:19 pm

2 stops27h 18m

$315

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Thu 4/30

3:27 pm-8:50 am

1 stop19h 23m

Santa Ana J. Wayne/Orange Cnty

Sun 5/3

5:01 pm-10:19 pm

2 stops27h 18m

$316

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Wed 4/29

2:15 pm-7:05 pm

1 stop6h 50m

Santa Ana J. Wayne/Orange Cnty

Mon 5/4

7:40 pm-5:00 am

1 stop7h 20m

$323

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Wed 4/29

6:10 am-11:05 am

1 stop6h 55m

Santa Ana J. Wayne/Orange Cnty

Mon 5/4

8:30 am-6:00 pm

2 stops7h 30m

$328

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Wed 5/27

7:30 am-2:00 pm

1 stop8h 30m

Santa Ana J. Wayne/Orange Cnty

Sat 5/30

6:10 pm-5:40 am

1 stop9h 30m

$329

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Thu 4/30

3:27 pm-8:50 am

1 stop19h 23m

Santa Ana J. Wayne/Orange Cnty

Sun 5/3

5:01 pm-3:04 pm

1 stop20h 03m

$332
Quickest round-trip

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Tue 4/21

10:10 am-1:55 pm

1 stop5h 45m

Santa Ana J. Wayne/Orange Cnty

Tue 4/28

7:50 pm-5:00 am

1 stop7h 10m

$337

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Chicago Midway Airport to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Chicago Midway Airport and Santa Ana, California?

What is the cheapest month to fly to Santa Ana, California?

In general, August is the cheapest month to fly from Chicago Midway Airport to Santa Ana, California. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $288. If you aren’t able to travel during the month of August, then book flights to Santa Ana, California from Chicago Midway Airport during September instead. Flights to Santa Ana, California in September, while not as cheap as those in August, still average around $288.

What is the cheapest day to depart on your flight to Santa Ana, California?

The cheapest day to depart from Chicago Midway Airport to Santa Ana, California is on a Saturday. Travelers who choose to depart for Santa Ana, California on a Saturday will often find tickets for as low as $357. The most expensive day to fly to Santa Ana, California is Sunday, with ticket prices averaging around $477.

What is the cheapest time of day to depart on your flight to Santa Ana, California?

In the morning is the cheapest time of day to fly from Chicago Midway Airport to Santa Ana, California when you can find flight prices for as low as $375. Flying to Santa Ana, California in the morning is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Santa Ana, California is in the evening when prices are around $408.

How have Chicago Midway Airport to Santa Ana, California flight prices changed over time?

When to book flights from Chicago Midway Airport to Santa Ana, California

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago Midway Airport to Santa Ana, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago Midway Airport to Santa Ana, California (MDW to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago Midway Airport to Santa Ana, California

Fastest flight time

5h 40m

Direct flights

None
The fastest flight from Chicago Midway Airport to Santa Ana, California takes 5h 40m
There are no direct flights from Chicago Midway Airport to Santa Ana, California. There are no popular flight routes from Chicago Midway Airport to Santa Ana, California.
Search flight deals

  • How far is Chicago Midway to Santa Ana J. Wayne/Orange Cnty by plane?

    Santa Ana J. Wayne/Orange Cnty is 1724.9 mi away from Chicago Midway. 5h 40m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Chicago Midway Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Chicago Midway Airport to Santa Ana J. Wayne/Orange Cnty Airport are updated daily.

  • How many operators does momondo search for flights from Chicago Midway Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Chicago Midway Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Chicago Midway Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The travel and health documents you'll need for your trip to Santa Ana J. Wayne/Orange Cnty Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santa Ana J. Wayne/Orange Cnty Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Chicago Midway Airport to Santa Ana, California?

Best airlines flying from Chicago Midway Airport to Santa Ana, California

Compare and see reviews for airlines that fly from Chicago Midway Airport to Santa Ana, California with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $288Free CancellationRating
8.0
4,335 reviews
Search Southwest flights

  • Southwest Flights From Chicago Midway Airport to Santa Ana, California

    Across 3 Southwest flights from Chicago Midway Airport to Santa Ana, California this week, the average price was $436, with the best Southwest deals starting from $288 round-trip. 4,335 users have rated Southwest on momondo, with an average score of 8.0/10.

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Santa Ana?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Santa Ana. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Santa Ana with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Chicago to Santa Ana flights to just show those with flexible booking policies.

How can momondo help me find flights from Chicago to Santa Ana?

Once you have performed a search for Chicago to Santa Ana flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Chicago to Santa Ana right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Santa Ana flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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