Cheap flights from Chicago Midway Airport to Knoxville from $57
This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago Midway Airport to Knoxville departing on 11/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Not ready to book? to track prices.Southwest flights from Chicago Midway Airport to Knoxville
Our best Southwest deals on Chicago Midway Airport to Knoxville flight tickets
Allegiant Air flights from Chicago Midway Airport to Knoxville
Our best Allegiant Air deals on Chicago Midway Airport to Knoxville flight tickets
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Fly from
Fly to
Route
Depart
Return
ChicagoKnoxville
MDW Chicago Midway - TYS Knoxville McGhee Tyson
MDWTYS
Chicago Midway
Fri 11/13
3:16 pm-5:46 pm
Nonstop1h 30m
Knoxville McGhee Tyson
Thu 11/19
6:30 am-11:47 pm
2 stops18h 17m
ChicagoKnoxville
MDW Chicago Midway - TYS Knoxville McGhee Tyson
MDWTYS
Chicago Midway
Fri 11/13
12:45 pm-9:45 pm
2 stops8h 00m
Knoxville McGhee Tyson
Mon 11/16
5:15 pm-10:45 pm
1 stop6h 30m
ChicagoKnoxville
MDW Chicago Midway - TYS Knoxville McGhee Tyson
MDWTYS
Chicago Midway
Mon 10/19
1:26 pm-3:51 pm
Nonstop1h 25m
Knoxville McGhee Tyson
Mon 10/26
12:04 pm-12:36 pm
Nonstop1h 32m
ChicagoKnoxville
MDW Chicago Midway - TYS Knoxville McGhee Tyson
MDWTYS
Chicago Midway
Mon 11/16
6:08 am-12:35 pm
2 stops29h 27m
Knoxville McGhee Tyson
Mon 11/23
8:00 am-8:39 am
Nonstop1h 39m
ChicagoKnoxville
MDW Chicago Midway - TYS Knoxville McGhee Tyson
MDWTYS
Chicago Midway
Fri 11/13
3:16 pm-5:46 pm
Nonstop1h 30m
Knoxville McGhee Tyson
Wed 11/18
12:56 pm-5:07 pm
1 stop29h 11m
ChicagoKnoxville
MDW Chicago Midway - TYS Knoxville McGhee Tyson
MDWTYS
Chicago Midway
Fri 11/13
3:16 pm-5:46 pm
Nonstop1h 30m
Knoxville McGhee Tyson
Sat 11/21
2:50 pm-5:07 pm
1 stop27h 17m
ChicagoKnoxville
MDW Chicago Midway - TYS Knoxville McGhee Tyson
MDWTYS
Chicago Midway
Fri 11/13
3:16 pm-5:46 pm
Nonstop1h 30m
Knoxville McGhee Tyson
Thu 11/19
3:42 pm-11:55 am
2 stops21h 13m
ChicagoKnoxville
MDW Chicago Midway - TYS Knoxville McGhee Tyson
MDWTYS
Chicago Midway
Fri 11/13
6:00 am-11:28 am
1 stop4h 28m
Knoxville McGhee Tyson
Mon 11/16
7:22 pm-10:54 pm
1 stop4h 32m
ChicagoKnoxville
MDW Chicago Midway - TYS Knoxville McGhee Tyson
MDWTYS
Chicago Midway
Sat 12/12
1:25 pm-7:45 pm
1 stop5h 20m
Knoxville McGhee Tyson
Sun 12/13
7:25 pm-12:05 am
1 stop5h 40m
ChicagoKnoxville
MDW Chicago Midway - TYS Knoxville McGhee Tyson
MDWTYS
Chicago Midway
Wed 11/4
8:00 am-12:20 pm
1 stop3h 20m
Knoxville McGhee Tyson
Wed 11/11
5:15 pm-10:45 pm
1 stop6h 30m
See travel insights to Knoxville from
How to get the cheapest flight ticket from Chicago Midway Airport to Knoxville
Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip
What is the typical price of a round-trip flight between Chicago Midway Airport and Knoxville?
Prices are currently high for flights on this route.
Typical prices usually range from $151 to $217.The lowest price recently found on this route was $254.
What is the cheapest month to fly to Knoxville?
The month of December is, on average, the cheapest month to fly to Knoxville from Chicago Midway Airport, with most prices found around $0. If you aren’t able to travel during the month of December, then book flights to Knoxville from Chicago Midway Airport during January instead. Flights to Knoxville in January, while not as cheap as those in December, still average around $0.
What is the cheapest day to depart on your flight to Knoxville?
The cheapest day to depart from Chicago Midway Airport to Knoxville is on a Thursday. Travelers who choose to depart for Knoxville on a Thursday will often find tickets for as low as $274. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from Chicago Midway Airport to Knoxville for around $404.
What is the cheapest time of day to depart on your flight to Knoxville?
At noon is the cheapest time of day to fly from Chicago Midway Airport to Knoxville when you can find flight prices for as low as $239. Flying to Knoxville at noon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the afternoon when prices are around $350.
What is the cheapest Chicago Midway to Knoxville McGhee Tyson flight route?
Fly from Chicago Midway to Knoxville McGhee Tyson for the best Chicago Midway - Knoxville McGhee Tyson flight prices
What cabin class options are available on Chicago Midway Airport to Knoxville flights?
There is only 1 cabin class available to choose from on Chicago Midway Airport to Knoxville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.
Can stopping save me money on Chicago Midway Airport to Knoxville flights?
No. A direct flight is the cheapest option for a flight between Chicago Midway Airport to Knoxville.
What is the cheapest airline that flies from Chicago Midway to Knoxville McGhee Tyson?
Southwest and Allegiant Air are the most popular carriers operating from Chicago Midway to Knoxville McGhee Tyson
What airlines fly to Knoxville?
Allegiant Air, Delta and Southwest are the top three most popular airlines that fly to Knoxville from Chicago Midway Airport according to our data. Allegiant Air is the first choice among our users, with 77% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 3 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.
When to book flights from Chicago Midway Airport to Knoxville
Cheap Chicago Midway Airport to Knoxville (MDW to TYS) flight deals and tips
Find info about flight duration, direct flights, and airports for your flight from Chicago Midway Airport to Knoxville
Frequently asked questions about flying from Chicago Midway Airport to Knoxville
How far is Chicago Midway to Knoxville McGhee Tyson by plane?
There are 451.6 mi between Chicago Midway and Knoxville McGhee Tyson. Flights usually cover this in 1h 25m, depending on flying conditions and air traffic around both airports.
When did momondo last update prices for flights from Chicago Midway Airport to Knoxville McGhee Tyson Airport?
Prices for flights from Chicago Midway Airport to Knoxville McGhee Tyson Airport refresh daily.
How many operators does momondo search for flights from Chicago Midway Airport to Knoxville McGhee Tyson Airport?
There are 2 operators available for flights from Chicago Midway Airport to Knoxville McGhee Tyson Airport as of October 2026.
How old do you have to be to fly from Chicago Midway Airport to Knoxville McGhee Tyson Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago Midway Airport to Knoxville McGhee Tyson Airport.
What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?
The necessary travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Chicago Midway Airport to Knoxville?
Based on momondo bookings for flights between Chicago Midway Airport and Knoxville, the leading plane model is Airbus A320-100/200, making up 27.49% of the total bookings. Other popular models include Canadair (Bombardier) Regional Jet CRJ-550 with 14.62%, Embraer 170 with 11.70%, and Canadair (Bombardier) Regional Jet 700 with 9.94%.
What is the most popular airline from Chicago Midway Airport to Knoxville?
momondo data reveals that the most frequently booked airline on the route from Chicago Midway Airport to Knoxville is Allegiant Air, representing 83% of all bookings. The subsequent popular airline is Southwest at 17%.
Best airlines flying from Chicago Midway Airport to Knoxville
Compare and see reviews for airlines that fly from Chicago Midway Airport to Knoxville with momondo
| Airline | Rating | Free Cancellation | Price | ||
|---|---|---|---|---|---|
| PriceFrom $82 | Free Cancellation | Rating 7.3 678 reviews | |||
| PriceFrom $161 | Free Cancellation | Rating 7.9 4,225 reviews |
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsWhy use momondo?
Why should I use momondo to find a flight deal from Chicago to Knoxville?
To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Knoxville from Chicago.
Can I find flights from Chicago to Knoxville with flexible booking policies on momondo?
Yes. All flights to Knoxville from Chicago on momondo can be compared and filtered by various policies on offer, including flexible booking.
How can momondo help me find flights from Chicago to Knoxville?
Once you have performed a search for Chicago to Knoxville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.
I’m not ready to book a flight from Chicago to Knoxville right now. Can momondo alert me if prices change?
Price alerts on flights to Knoxville from Chicago are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.