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Cheap flights from Chicago Midway Airport to Knoxville from $57

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago Midway Airport to Knoxville departing on 7/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Chicago Midway Airport to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
2:48 pm - 5:18 pm
MDW
-
TYS
1h 30mnonstop
Allegiant Air Logo
9:00 am - 8:18 am
TYS
-
MDW
24h 18m
1 stop
$204Allegiant Air
Thu, Jul 2 - Sat, Jul 4
Allegiant Air Logo
2:46 pm - 5:14 pm
MDW
-
TYS
1h 28mnonstop
Allegiant Air Logo
1:22 pm - 1:56 pm
TYS
-
MDW
1h 34mnonstop
$206Allegiant Air
Sun, Jun 14 - Thu, Jun 18
Multiple Airlines Logo
2:48 pm - 5:18 pm
MDW
-
TYS
1h 30mnonstop
Multiple Airlines Logo
10:05 pm - 10:11 pm
TYS
-
MDW
25h 06m
2 stops
$214Multiple Airlines
Thu, Jul 2 - Fri, Jul 3
Allegiant Air Logo
2:46 pm - 5:14 pm
MDW
-
TYS
1h 28mnonstop
Allegiant Air Logo
1:22 pm - 1:56 pm
TYS
-
MDW
1h 34mnonstop
$220Allegiant Air
Sun, Jun 14 - Thu, Jun 18
Multiple Airlines Logo
6:00 am - 3:55 pm
MDW
-
TYS
32h 55m
2 stops
Multiple Airlines Logo
1:22 pm - 1:58 pm
TYS
-
MDW
1h 36mnonstop
$221Multiple Airlines
Mon, Jun 29 - Sun, Jul 5
Multiple Airlines Logo
8:41 am - 10:24 pm
MDW
-
TYS
12h 43m
1 stop
Multiple Airlines Logo
5:39 pm - 10:02 pm
TYS
-
MDW
29h 23m
2 stops
$223Multiple Airlines
Mon, May 4 - Mon, May 11
Allegiant Air Logo
2:48 pm - 5:18 pm
MDW
-
TYS
1h 30mnonstop
Allegiant Air Logo
9:00 am - 8:18 am
TYS
-
MDW
24h 18m
1 stop
$226Allegiant Air
Thu, Jul 2 - Wed, Jul 8
Allegiant Air Logo
2:46 pm - 5:14 pm
MDW
-
TYS
1h 28mnonstop
Allegiant Air Logo
1:22 pm - 1:56 pm
TYS
-
MDW
1h 34mnonstop
$227Allegiant Air
Thu, Jun 11 - Thu, Jun 18
Multiple Airlines Logo
2:48 pm - 5:18 pm
MDW
-
TYS
1h 30mnonstop
Multiple Airlines Logo
10:05 pm - 10:11 pm
TYS
-
MDW
25h 06m
2 stops
$230Multiple Airlines
Thu, Jul 2 - Mon, Jul 6
Multiple Airlines Logo
2:47 pm - 5:13 pm
MDW
-
TYS
1h 26mnonstop
Multiple Airlines Logo
7:24 pm - 11:12 am
TYS
-
MDW
16h 48m
2 stops
$231Multiple Airlines
Thu, May 28 - Mon, Jun 1

Delta flights from Chicago Midway Airport to Knoxville

Our best Delta deals on Chicago Midway Airport to Knoxville flight tickets
Delta
Jun 30
MDW5:41 pmChicago Midway
5h 13m
1 stop
TYS11:54 pmKnoxville McGhee Tyson
Jul 3
TYS3:36 pmKnoxville McGhee Tyson
3h 55m
1 stop
MDW6:31 pmChicago Midway
$264
Delta
Jun 29
MDW5:41 pmChicago Midway
5h 13m
1 stop
TYS11:54 pmKnoxville McGhee Tyson
Jul 1
TYS3:36 pmKnoxville McGhee Tyson
3h 55m
1 stop
MDW6:31 pmChicago Midway
$269
Delta
Jul 1
MDW6:05 amChicago Midway
4h 04m
1 stop
TYS11:09 amKnoxville McGhee Tyson
Jul 7
TYS6:05 pmKnoxville McGhee Tyson
5h 10m
1 stop
MDW10:15 pmChicago Midway
$294

Allegiant Air flights from Chicago Midway Airport to Knoxville

Our best Allegiant Air deals on Chicago Midway Airport to Knoxville flight tickets
Allegiant Air
Jul 2
MDW2:48 pmChicago Midway
1h 30m
TYS5:18 pmKnoxville McGhee Tyson
Jul 4
TYS9:00 amKnoxville McGhee Tyson
24h 18m
1 stop
MDW8:18 amChicago Midway
$204
Allegiant Air
Jun 14
MDW2:46 pmChicago Midway
1h 28m
TYS5:14 pmKnoxville McGhee Tyson
Jun 18
TYS1:22 pmKnoxville McGhee Tyson
1h 34m
MDW1:56 pmChicago Midway
$206
Allegiant Air
Jun 14
MDW2:46 pmChicago Midway
1h 28m
TYS5:14 pmKnoxville McGhee Tyson
Jun 18
TYS1:22 pmKnoxville McGhee Tyson
1h 34m
MDW1:56 pmChicago Midway
$220

momondo Fare Finder

 
Customize your flight search to find flights from Chicago Midway Airport to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 7, 2026.
Use the filters below to find and compare flights from Chicago Midway Airport to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Thu 7/2

2:48 pm-5:18 pm

Nonstop1h 30m

Knoxville McGhee Tyson

Sat 7/4

9:00 am-8:18 am

1 stop24h 18m

$204
Quickest round-trip

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Sun 6/14

2:46 pm-5:14 pm

Nonstop1h 28m

Knoxville McGhee Tyson

Thu 6/18

1:22 pm-1:56 pm

Nonstop1h 34m

$206

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Thu 7/2

2:48 pm-5:18 pm

Nonstop1h 30m

Knoxville McGhee Tyson

Fri 7/3

10:05 pm-10:11 pm

2 stops25h 06m

$214

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Sun 6/14

2:46 pm-5:14 pm

Nonstop1h 28m

Knoxville McGhee Tyson

Thu 6/18

1:22 pm-1:56 pm

Nonstop1h 34m

$220

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Mon 6/29

6:00 am-3:55 pm

2 stops32h 55m

Knoxville McGhee Tyson

Sun 7/5

1:22 pm-1:58 pm

Nonstop1h 36m

$221

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Mon 5/4

8:41 am-10:24 pm

1 stop12h 43m

Knoxville McGhee Tyson

Mon 5/11

5:39 pm-10:02 pm

2 stops29h 23m

$223

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Thu 7/2

2:48 pm-5:18 pm

Nonstop1h 30m

Knoxville McGhee Tyson

Wed 7/8

9:00 am-8:18 am

1 stop24h 18m

$226

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Thu 6/11

2:46 pm-5:14 pm

Nonstop1h 28m

Knoxville McGhee Tyson

Thu 6/18

1:22 pm-1:56 pm

Nonstop1h 34m

$227

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Thu 7/2

2:48 pm-5:18 pm

Nonstop1h 30m

Knoxville McGhee Tyson

Mon 7/6

10:05 pm-10:11 pm

2 stops25h 06m

$230

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Thu 5/28

2:47 pm-5:13 pm

Nonstop1h 26m

Knoxville McGhee Tyson

Mon 6/1

7:24 pm-11:12 am

2 stops16h 48m

$231

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Chicago Midway Airport to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Chicago Midway Airport and Knoxville?

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Chicago Midway Airport to Knoxville is on a Saturday. Travelers who choose to depart for Knoxville on a Saturday will often find tickets for as low as $268. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Chicago Midway Airport to Knoxville for around $318.

What is the cheapest time of day to depart on your flight to Knoxville?

At noon is the cheapest time of day to fly from Chicago Midway Airport to Knoxville when you can find flight prices for as low as $262. Flying to Knoxville at noon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the afternoon when prices are around $315.

What is the cheapest Chicago Midway to Knoxville McGhee Tyson flight route?

Fly from Chicago Midway to Knoxville McGhee Tyson for the best Chicago Midway - Knoxville McGhee Tyson flight prices

What cabin class options are available on Chicago Midway to Knoxville McGhee Tyson flights?

There is only 1 cabin class available to choose from on Chicago Midway to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

When to book flights from Chicago Midway Airport to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago Midway Airport to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago Midway Airport to Knoxville (MDW to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago Midway Airport to Knoxville

Best Price Found

$106

Fastest flight time

1h 25m

Direct flights

Mon and Fri

Airports in Knoxville

1 airport
The best flight deal from Chicago Midway Airport to Knoxville found on momondo in the last 72 hours is $106
The fastest flight from Chicago Midway Airport to Knoxville takes 1h 25m
Direct flights go from Chicago Midway Airport to Knoxville on Monday and Friday. The only airline offering direct flights is Allegiant Air.
There is 1 airport in Knoxville. From Chicago Midway Airport there are direct flights to Knoxville McGhee Tyson (TYS).
Search flight deals

Frequently asked questions about flying from Chicago Midway Airport to Knoxville

  • How far is Chicago Midway to Knoxville McGhee Tyson by plane?

    There are 451.6 mi between Chicago Midway and Knoxville McGhee Tyson. Flights usually cover this in 1h 25m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Chicago Midway Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Chicago Midway Airport to Knoxville McGhee Tyson Airport refresh daily.

  • How many operators does momondo search for flights from Chicago Midway Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Chicago Midway Airport to Knoxville McGhee Tyson Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago Midway Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The necessary travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Chicago Midway Airport to Knoxville?

  • What is the most popular airline from Chicago Midway Airport to Knoxville?

Best airlines flying from Chicago Midway Airport to Knoxville

Compare and see reviews for airlines that fly from Chicago Midway Airport to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $61Free CancellationRating
7.3
706 reviews
Search Allegiant Air flights
DeltaPriceFrom $138Free CancellationRating
7.9
8,387 reviews
Search Delta flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Maryville
Crossville
Alcoa
Murphy
Oak Ridge
Newport
Lenoir City
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Knoxville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Knoxville from Chicago.

Can I find flights from Chicago to Knoxville with flexible booking policies on momondo?

Yes. All flights to Knoxville from Chicago on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Chicago to Knoxville?

Once you have performed a search for Chicago to Knoxville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Chicago to Knoxville right now. Can momondo alert me if prices change?

Price alerts on flights to Knoxville from Chicago are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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