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Cheap flights from Chicago Midway Airport to Knoxville from $59

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago Midway Airport to Knoxville departing on 5/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Chicago Midway Airport to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
2:47 pm - 5:13 pm
MDW
-
TYS
1h 26mnonstop
Allegiant Air Logo
1:22 pm - 1:57 pm
TYS
-
MDW
1h 35mnonstop
$140Allegiant Air
Thu, May 28 - Sun, May 31
Allegiant Air Logo
2:46 pm - 5:14 pm
MDW
-
TYS
1h 28mnonstop
Allegiant Air Logo
1:22 pm - 1:56 pm
TYS
-
MDW
1h 34mnonstop
$150Allegiant Air
Thu, Jun 4 - Thu, Jun 11
Allegiant Air Logo
2:46 pm - 5:14 pm
MDW
-
TYS
1h 28mnonstop
Allegiant Air Logo
1:22 pm - 1:56 pm
TYS
-
MDW
1h 34mnonstop
$154Allegiant Air
Thu, Jun 4 - Thu, Jun 11
Allegiant Air Logo
2:46 pm - 5:14 pm
MDW
-
TYS
1h 28mnonstop
Allegiant Air Logo
1:22 pm - 1:56 pm
TYS
-
MDW
1h 34mnonstop
$159Allegiant Air
Thu, Jun 25 - Sun, Jun 28
Allegiant Air Logo
2:47 pm - 5:13 pm
MDW
-
TYS
1h 26mnonstop
Allegiant Air Logo
1:22 pm - 1:56 pm
TYS
-
MDW
1h 34mnonstop
$160Allegiant Air
Thu, May 28 - Thu, Jun 4
Allegiant Air Logo
2:46 pm - 5:14 pm
MDW
-
TYS
1h 28mnonstop
Allegiant Air Logo
1:22 pm - 1:56 pm
TYS
-
MDW
1h 34mnonstop
$162Allegiant Air
Thu, Jun 11 - Sun, Jun 21
Allegiant Air Logo
2:47 pm - 5:13 pm
MDW
-
TYS
1h 26mnonstop
Allegiant Air Logo
1:22 pm - 1:57 pm
TYS
-
MDW
1h 35mnonstop
$166Allegiant Air
Thu, May 28 - Sun, May 31
Multiple Airlines Logo
2:47 pm - 5:13 pm
MDW
-
TYS
1h 26mnonstop
Multiple Airlines Logo
12:55 pm - 10:02 pm
TYS
-
MDW
34h 07m
2 stops
$167Multiple Airlines
Sun, May 31 - Mon, Jun 1
Allegiant Air Logo
2:47 pm - 5:13 pm
MDW
-
TYS
1h 26mnonstop
Allegiant Air Logo
1:22 pm - 1:56 pm
TYS
-
MDW
1h 34mnonstop
$169Allegiant Air
Sun, May 31 - Thu, Jun 4
Multiple Airlines Logo
6:00 am - 4:40 pm
MDW
-
TYS
33h 40m
2 stops
Multiple Airlines Logo
1:22 pm - 1:56 pm
TYS
-
MDW
1h 34mnonstop
$171Multiple Airlines
Thu, Jun 4 - Thu, Jun 25

Allegiant Air flights from Chicago Midway Airport to Knoxville

Our best Allegiant Air deals on Chicago Midway Airport to Knoxville flight tickets
Allegiant Air
May 28
MDW2:47 pmChicago Midway
1h 26m
TYS5:13 pmKnoxville McGhee Tyson
May 31
TYS1:22 pmKnoxville McGhee Tyson
1h 35m
MDW1:57 pmChicago Midway
$140
Allegiant Air
Jun 4
MDW2:46 pmChicago Midway
1h 28m
TYS5:14 pmKnoxville McGhee Tyson
Jun 11
TYS1:22 pmKnoxville McGhee Tyson
1h 34m
MDW1:56 pmChicago Midway
$150
Allegiant Air
Jun 4
MDW2:46 pmChicago Midway
1h 28m
TYS5:14 pmKnoxville McGhee Tyson
Jun 11
TYS1:22 pmKnoxville McGhee Tyson
1h 34m
MDW1:56 pmChicago Midway
$154

Southwest flights from Chicago Midway Airport to Knoxville

Our best Southwest deals on Chicago Midway Airport to Knoxville flight tickets
Southwest
May 24
MDW9:00 amChicago Midway
8h 45m
2 stops
TYS6:45 pmKnoxville McGhee Tyson
May 30
TYS7:45 amKnoxville McGhee Tyson
11h 30m
1 stop
MDW6:15 pmChicago Midway
$303
Southwest
May 24
MDW9:00 amChicago Midway
8h 45m
2 stops
TYS6:45 pmKnoxville McGhee Tyson
May 30
TYS6:40 amKnoxville McGhee Tyson
11h 30m
2 stops
MDW5:10 pmChicago Midway
$308
Southwest
May 24
MDW9:00 amChicago Midway
4h 45m
1 stop
TYS2:45 pmKnoxville McGhee Tyson
May 28
TYS6:35 amKnoxville McGhee Tyson
9h 05m
1 stop
MDW2:40 pmChicago Midway
$314

momondo Fare Finder

 
Customize your flight search to find flights from Chicago Midway Airport to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 10, 2026.
Use the filters below to find and compare flights from Chicago Midway Airport to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Thu 5/28

2:47 pm-5:13 pm

Nonstop1h 26m

Knoxville McGhee Tyson

Sun 5/31

1:22 pm-1:57 pm

Nonstop1h 35m

$140

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Thu 6/4

2:46 pm-5:14 pm

Nonstop1h 28m

Knoxville McGhee Tyson

Thu 6/11

1:22 pm-1:56 pm

Nonstop1h 34m

$150

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Thu 6/4

2:46 pm-5:14 pm

Nonstop1h 28m

Knoxville McGhee Tyson

Thu 6/11

1:22 pm-1:56 pm

Nonstop1h 34m

$154

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Thu 6/25

2:46 pm-5:14 pm

Nonstop1h 28m

Knoxville McGhee Tyson

Sun 6/28

1:22 pm-1:56 pm

Nonstop1h 34m

$159
Quickest round-trip

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Thu 5/28

2:47 pm-5:13 pm

Nonstop1h 26m

Knoxville McGhee Tyson

Thu 6/4

1:22 pm-1:56 pm

Nonstop1h 34m

$160

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Thu 6/11

2:46 pm-5:14 pm

Nonstop1h 28m

Knoxville McGhee Tyson

Sun 6/21

1:22 pm-1:56 pm

Nonstop1h 34m

$162

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Thu 5/28

2:47 pm-5:13 pm

Nonstop1h 26m

Knoxville McGhee Tyson

Sun 5/31

1:22 pm-1:57 pm

Nonstop1h 35m

$166

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Sun 5/31

2:47 pm-5:13 pm

Nonstop1h 26m

Knoxville McGhee Tyson

Mon 6/1

12:55 pm-10:02 pm

2 stops34h 07m

$167

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Sun 5/31

2:47 pm-5:13 pm

Nonstop1h 26m

Knoxville McGhee Tyson

Thu 6/4

1:22 pm-1:56 pm

Nonstop1h 34m

$169

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Thu 6/4

6:00 am-4:40 pm

2 stops33h 40m

Knoxville McGhee Tyson

Thu 6/25

1:22 pm-1:56 pm

Nonstop1h 34m

$171

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Chicago Midway Airport to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Chicago Midway Airport and Knoxville?

What is the cheapest month to fly to Knoxville?

The month of December is, on average, the cheapest month to fly to Knoxville from Chicago Midway Airport, with most prices found around $0. If you aren’t able to travel during the month of December, then book flights to Knoxville from Chicago Midway Airport during January instead. Flights to Knoxville in January, while not as cheap as those in December, still average around $0.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Chicago Midway Airport to Knoxville is on a Wednesday. Travelers who choose to depart for Knoxville on a Wednesday will often find tickets for as low as $274. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Chicago Midway Airport to Knoxville for around $325.

What is the cheapest time of day to depart on your flight to Knoxville?

At noon is the cheapest time of day to fly from Chicago Midway Airport to Knoxville when you can find flight prices for as low as $253. Flying to Knoxville at noon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the afternoon when prices are around $326.

What is the cheapest Chicago Midway to Knoxville McGhee Tyson flight route?

Fly from Chicago Midway to Knoxville McGhee Tyson for the best Chicago Midway - Knoxville McGhee Tyson flight prices

When to book flights from Chicago Midway Airport to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago Midway Airport to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago Midway Airport to Knoxville (MDW to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago Midway Airport to Knoxville

Best Price Found

$72

Fastest flight time

1h 25m

Direct flights

Mon, Tue, Fri and Sat

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from Chicago Midway Airport in the past 72 hours is $72. The best round-trip flight deal from Chicago Midway Airport to Knoxville found on momondo in the last 72 hours is $120.
The fastest flight from Chicago Midway Airport to Knoxville takes 1h 25m
Direct flights go from Chicago Midway Airport to Knoxville on Monday, Tuesday, Friday and Saturday. The only airline offering direct flights is Allegiant Air.
There is 1 airport in Knoxville. From Chicago Midway Airport there are direct flights to Knoxville McGhee Tyson (TYS).
Search flight deals

Frequently asked questions about flying from Chicago Midway Airport to Knoxville

  • How far is Chicago Midway to Knoxville McGhee Tyson by plane?

    There are 451.6 mi between Chicago Midway and Knoxville McGhee Tyson. Flights usually cover this in 1h 25m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Chicago Midway Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Chicago Midway Airport to Knoxville McGhee Tyson Airport refresh daily.

  • How many operators does momondo search for flights from Chicago Midway Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Chicago Midway Airport to Knoxville McGhee Tyson Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago Midway Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The necessary travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Chicago Midway Airport to Knoxville?

  • What is the most popular airline from Chicago Midway Airport to Knoxville?

Best airlines flying from Chicago Midway Airport to Knoxville

Compare and see reviews for airlines that fly from Chicago Midway Airport to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $61Free CancellationRating
7.3
709 reviews
Search Allegiant Air flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Alcoa
Corbin
Crossville
Maryville
Murphy
Oak Ridge
Newport
Lenoir City
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Knoxville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Knoxville from Chicago.

Can I find flights from Chicago to Knoxville with flexible booking policies on momondo?

Yes. All flights to Knoxville from Chicago on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Chicago to Knoxville?

Once you have performed a search for Chicago to Knoxville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Chicago to Knoxville right now. Can momondo alert me if prices change?

Price alerts on flights to Knoxville from Chicago are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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