Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Chicago Midway Airport to Knoxville from $51

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago Midway Airport to Knoxville departing on 9/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Chicago Midway Airport to Knoxville

Cheap round-trip flights

Allegiant Air Logo
7:50 pm - 10:21 pmMDW-TYS
1h 31mnonstop
Allegiant Air Logo
1:50 pm - 2:26 pmTYS-MDW
1h 36mnonstop
$131Allegiant Air
Find Deal
Fri, Sep 26 - Mon, Sep 29
Allegiant Air Logo
3:27 pm - 5:52 pmMDW-TYS
1h 25mnonstop
Allegiant Air Logo
2:47 pm - 3:22 pmTYS-MDW
1h 35mnonstop
$132Allegiant Air
Find Deal
Fri, Nov 14 - Mon, Nov 17
Allegiant Air Logo
7:50 pm - 10:21 pmMDW-TYS
1h 31mnonstop
Allegiant Air Logo
1:50 pm - 2:26 pmTYS-MDW
1h 36mnonstop
$134Allegiant Air
Find Deal
Fri, Sep 26 - Mon, Sep 29
Allegiant Air Logo
12:08 pm - 2:32 pmMDW-TYS
1h 24mnonstop
Allegiant Air Logo
10:44 am - 11:16 amTYS-MDW
1h 32mnonstop
$140Allegiant Air
Find Deal
Mon, Oct 13 - Fri, Oct 17
Allegiant Air Logo
2:45 pm - 5:09 pmMDW-TYS
1h 24mnonstop
Allegiant Air Logo
5:44 pm - 6:16 pmTYS-MDW
1h 32mnonstop
$159Allegiant Air
Find Deal
Fri, Oct 24 - Fri, Oct 31
Allegiant Air Logo
12:08 pm - 2:32 pmMDW-TYS
1h 24mnonstop
Allegiant Air Logo
10:44 am - 11:16 amTYS-MDW
1h 32mnonstop
$160Allegiant Air
Find Deal
Mon, Oct 6 - Fri, Oct 10
Logo
7:50 pm - 10:21 pmMDW-TYS
1h 31mnonstop
Logo
6:19 pm - 8:53 amTYS-MDW
15h 34m1 stop
$170
Find Deal
Mon, Sep 15 - Thu, Sep 18
Delta Logo
6:00 am - 10:46 amMDW-TYS
3h 46m1 stop
Delta Logo
7:45 am - 12:28 pmTYS-MDW
5h 43m1 stop
$209Delta
Find Deal
Tue, Oct 7 - Thu, Oct 16
Delta Logo
1:08 pm - 6:23 pmMDW-TYS
4h 15m1 stop
Delta Logo
7:49 am - 12:28 pmTYS-MDW
5h 39m1 stop
$219Delta
Find Deal
Sat, Sep 13 - Tue, Sep 16
Delta Logo
6:00 am - 10:56 amMDW-TYS
3h 56m1 stop
Delta Logo
5:45 am - 9:48 amTYS-MDW
5h 03m1 stop
$234Delta
Find Deal
Tue, Sep 23 - Sat, Sep 27

Delta flights from Chicago Midway Airport to Knoxville

Our best Delta deals on Chicago Midway Airport to Knoxville flight tickets
Delta
Oct 7
MDW6:00 amChicago Midway
3h 46m
1 stop
TYS10:46 amKnoxville McGhee Tyson
Oct 16
TYS7:45 amKnoxville McGhee Tyson
5h 43m
1 stop
MDW12:28 pmChicago Midway
$209
Find similar
Delta
Sep 13
MDW1:08 pmChicago Midway
4h 15m
1 stop
TYS6:23 pmKnoxville McGhee Tyson
Sep 16
TYS7:49 amKnoxville McGhee Tyson
5h 39m
1 stop
MDW12:28 pmChicago Midway
$219
Find similar
Delta
Sep 23
MDW6:00 amChicago Midway
3h 56m
1 stop
TYS10:56 amKnoxville McGhee Tyson
Sep 27
TYS5:45 amKnoxville McGhee Tyson
5h 03m
1 stop
MDW9:48 amChicago Midway
$234
Find similar

Allegiant Air flights from Chicago Midway Airport to Knoxville

Our best Allegiant Air deals on Chicago Midway Airport to Knoxville flight tickets
Allegiant Air
Sep 26
MDW7:50 pmChicago Midway
1h 31m
TYS10:21 pmKnoxville McGhee Tyson
Sep 29
TYS1:50 pmKnoxville McGhee Tyson
1h 36m
MDW2:26 pmChicago Midway
$131
Find similar
Allegiant Air
Nov 14
MDW3:27 pmChicago Midway
1h 25m
TYS5:52 pmKnoxville McGhee Tyson
Nov 17
TYS2:47 pmKnoxville McGhee Tyson
1h 35m
MDW3:22 pmChicago Midway
$132
Find similar
Allegiant Air
Sep 26
MDW7:50 pmChicago Midway
1h 31m
TYS10:21 pmKnoxville McGhee Tyson
Sep 29
TYS1:50 pmKnoxville McGhee Tyson
1h 36m
MDW2:26 pmChicago Midway
$134
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Chicago Midway Airport to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 29, 2025.
Use the filters below to find and compare flights from Chicago Midway Airport to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Fri 9/26

7:50 pm-10:21 pm

Nonstop1h 31m

Knoxville McGhee Tyson

Mon 9/29

1:50 pm-2:26 pm

Nonstop1h 36m

$131

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Fri 11/14

3:27 pm-5:52 pm

Nonstop1h 25m

Knoxville McGhee Tyson

Mon 11/17

2:47 pm-3:22 pm

Nonstop1h 35m

$132

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Fri 9/26

7:50 pm-10:21 pm

Nonstop1h 31m

Knoxville McGhee Tyson

Mon 9/29

1:50 pm-2:26 pm

Nonstop1h 36m

$134

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Mon 10/13

12:08 pm-2:32 pm

Nonstop1h 24m

Knoxville McGhee Tyson

Fri 10/17

10:44 am-11:16 am

Nonstop1h 32m

$140

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Fri 10/24

2:45 pm-5:09 pm

Nonstop1h 24m

Knoxville McGhee Tyson

Fri 10/31

5:44 pm-6:16 pm

Nonstop1h 32m

$159

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Mon 10/6

12:08 pm-2:32 pm

Nonstop1h 24m

Knoxville McGhee Tyson

Fri 10/10

10:44 am-11:16 am

Nonstop1h 32m

$160

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Mon 9/15

7:50 pm-10:21 pm

Nonstop1h 31m

Knoxville McGhee Tyson

Thu 9/18

6:19 pm-8:53 am

1 stop15h 34m

$170

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Tue 10/7

6:00 am-10:46 am

1 stop3h 46m

Knoxville McGhee Tyson

Thu 10/16

7:45 am-12:28 pm

1 stop5h 43m

$209

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Sat 9/13

1:08 pm-6:23 pm

1 stop4h 15m

Knoxville McGhee Tyson

Tue 9/16

7:49 am-12:28 pm

1 stop5h 39m

$219

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Tue 9/23

6:00 am-10:56 am

1 stop3h 56m

Knoxville McGhee Tyson

Sat 9/27

5:45 am-9:48 am

1 stop5h 03m

$234

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Knoxville from

How to get the cheapest flight ticket from Chicago Midway Airport to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Chicago Midway Airport to Knoxville is on a Wednesday. Travelers who choose to depart for Knoxville on a Wednesday will often find tickets for as low as $268. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Chicago Midway Airport to Knoxville for around $313.

What is the cheapest time of day to depart on your flight to Knoxville?

At noon is the cheapest time of day to fly from Chicago Midway Airport to Knoxville when you can find flight prices for as low as $263. Flying to Knoxville at noon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the morning when prices are around $291.

What is the cheapest Chicago Midway to Knoxville McGhee Tyson flight route?

Fly from Chicago Midway to Knoxville McGhee Tyson for the best Chicago Midway - Knoxville McGhee Tyson flight prices

What cabin class options are available on Chicago Midway to Knoxville McGhee Tyson flights?

There is only 1 cabin class available to choose from on Chicago Midway to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

When to book flights from Chicago Midway Airport to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago Midway Airport to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago Midway Airport to Knoxville (MDW to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago Midway Airport to Knoxville

Best Price Found

$52

Fastest flight time

1h 24m

Direct flights

Tue, Thu and Sat

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from Chicago Midway Airport in the past 72 hours is $52. The best round-trip flight deal from Chicago Midway Airport to Knoxville found on momondo in the last 72 hours is $88.
The fastest flight from Chicago Midway Airport to Knoxville takes 1h 24m
Direct flights go from Chicago Midway Airport to Knoxville on Tuesday, Thursday and Saturday. The only airline offering direct flights is Allegiant Air.
There is 1 airport near Knoxville: Knoxville McGhee Tyson (TYS)
Search flight deals

  • How far is Chicago Midway to Knoxville McGhee Tyson by plane?

    There are 451.6 mi between Chicago Midway and Knoxville McGhee Tyson. Flights usually cover this in 1h 24m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Chicago Midway Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Chicago Midway Airport to Knoxville McGhee Tyson Airport refresh daily.

  • How many operators does momondo search for flights from Chicago Midway Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Chicago Midway Airport to Knoxville McGhee Tyson Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago Midway Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The necessary travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Chicago Midway Airport to Knoxville?

  • What is the most popular airline from Chicago Midway Airport to Knoxville?

Best airlines flying from Chicago Midway Airport to Knoxville

Compare and see reviews for airlines that fly from Chicago Midway Airport to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $77Free CancellationRating
7.2
701 reviews
Search Allegiant Air flights
DeltaPriceFrom $188Free CancellationRating
7.9
7,979 reviews
Search Delta flights

  • Allegiant Air Flights From Chicago Midway Airport to Knoxville

    Allegiant Air flight deals from Chicago Midway Airport to Knoxville start from $77 round-trip. Over the 1 Allegiant Air flight for this route in a normal week, average airfare is usually $115 round-trip - but some users have found much cheaper deals with momondo.

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Crossville
Maryville
Murphy
Newport
Alcoa
Lenoir City
Oak Ridge
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Knoxville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Knoxville from Chicago.

Can I find flights from Chicago to Knoxville with flexible booking policies on momondo?

Yes. All flights to Knoxville from Chicago on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Chicago to Knoxville?

Once you have performed a search for Chicago to Knoxville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Chicago to Knoxville right now. Can momondo alert me if prices change?

Price alerts on flights to Knoxville from Chicago are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Knoxville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 9/3
Wed 9/10
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States