Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Chicago Midway Airport to Knoxville from $52

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago Midway Airport to Knoxville departing on 8/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Chicago Midway Airport to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
2:48 pm - 5:18 pm
MDW
-
TYS
1h 30mnonstop
Allegiant Air Logo
1:22 pm - 1:58 pm
TYS
-
MDW
1h 36mnonstop
$137Allegiant Air
Thu, Jul 16 - Sun, Jul 19
Allegiant Air Logo
2:24 pm - 4:49 pm
MDW
-
TYS
1h 25mnonstop
Allegiant Air Logo
11:14 am - 11:46 am
TYS
-
MDW
1h 32mnonstop
$139Allegiant Air
Fri, Oct 2 - Fri, Oct 9
Allegiant Air Logo
2:48 pm - 5:18 pm
MDW
-
TYS
1h 30mnonstop
Allegiant Air Logo
1:22 pm - 1:58 pm
TYS
-
MDW
1h 36mnonstop
$140Allegiant Air
Thu, Jul 9 - Sun, Jul 12
Allegiant Air Logo
1:26 pm - 3:51 pm
MDW
-
TYS
1h 25mnonstop
Allegiant Air Logo
3:08 pm - 3:40 pm
TYS
-
MDW
1h 32mnonstop
$147Allegiant Air
Mon, Oct 12 - Fri, Oct 16
Allegiant Air Logo
2:47 pm - 5:13 pm
MDW
-
TYS
1h 26mnonstop
Allegiant Air Logo
1:22 pm - 1:57 pm
TYS
-
MDW
1h 35mnonstop
$148Allegiant Air
Thu, May 21 - Sun, May 24
Allegiant Air Logo
2:46 pm - 5:14 pm
MDW
-
TYS
1h 28mnonstop
Allegiant Air Logo
1:22 pm - 1:56 pm
TYS
-
MDW
1h 34mnonstop
$163Allegiant Air
Thu, Jun 18 - Sun, Jun 21
Multiple Airlines Logo
2:47 pm - 5:13 pm
MDW
-
TYS
1h 26mnonstop
Multiple Airlines Logo
12:55 pm - 11:12 am
TYS
-
MDW
23h 17m
2 stops
$171Multiple Airlines
Thu, May 28 - Mon, Jun 1
Allegiant Air Logo
9:30 pm - 7:31 pm
MDW
-
TYS
21h 01m
1 stop
Allegiant Air Logo
1:22 pm - 1:57 pm
TYS
-
MDW
1h 35mnonstop
$172Allegiant Air
Mon, May 25 - Thu, May 28
Allegiant Air Logo
2:46 pm - 5:14 pm
MDW
-
TYS
1h 28mnonstop
Allegiant Air Logo
1:22 pm - 1:56 pm
TYS
-
MDW
1h 34mnonstop
$174Allegiant Air
Sun, Jun 14 - Sun, Jun 21
Multiple Airlines Logo
12:27 pm - 4:40 pm
MDW
-
TYS
27h 13m
2 stops
Multiple Airlines Logo
1:22 pm - 1:57 pm
TYS
-
MDW
1h 35mnonstop
$176Multiple Airlines
Thu, May 28 - Sun, May 31

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Southwest flights from Chicago Midway Airport to Knoxville

Our best Southwest deals on Chicago Midway Airport to Knoxville flight tickets
Southwest
May 18
MDW3:50 pmChicago Midway
3h 30m
1 stop
TYS8:20 pmKnoxville McGhee Tyson
May 21
TYS6:45 pmKnoxville McGhee Tyson
5h 45m
1 stop
MDW11:30 pmChicago Midway
$299
Southwest
May 18
MDW5:30 amChicago Midway
5h 10m
1 stop
TYS11:40 amKnoxville McGhee Tyson
May 20
TYS12:50 pmKnoxville McGhee Tyson
7h 55m
2 stops
MDW7:45 pmChicago Midway
$334
Southwest
May 18
MDW9:30 amChicago Midway
7h 40m
1 stop
TYS6:10 pmKnoxville McGhee Tyson
May 25
TYS6:45 pmKnoxville McGhee Tyson
5h 00m
2 stops
MDW10:45 pmChicago Midway
$353

Allegiant Air flights from Chicago Midway Airport to Knoxville

Our best Allegiant Air deals on Chicago Midway Airport to Knoxville flight tickets
Allegiant Air
Jul 16
MDW2:48 pmChicago Midway
1h 30m
TYS5:18 pmKnoxville McGhee Tyson
Jul 19
TYS1:22 pmKnoxville McGhee Tyson
1h 36m
MDW1:58 pmChicago Midway
$137
Allegiant Air
Jul 9
MDW2:48 pmChicago Midway
1h 30m
TYS5:18 pmKnoxville McGhee Tyson
Jul 12
TYS1:22 pmKnoxville McGhee Tyson
1h 36m
MDW1:58 pmChicago Midway
$140
Allegiant Air
May 21
MDW2:47 pmChicago Midway
1h 26m
TYS5:13 pmKnoxville McGhee Tyson
May 24
TYS1:22 pmKnoxville McGhee Tyson
1h 35m
MDW1:57 pmChicago Midway
$148

momondo Fare Finder

 
Customize your flight search to find flights from Chicago Midway Airport to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 4, 2026.
Use the filters below to find and compare flights from Chicago Midway Airport to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Thu 7/16

2:48 pm-5:18 pm

Nonstop1h 30m

Knoxville McGhee Tyson

Sun 7/19

1:22 pm-1:58 pm

Nonstop1h 36m

$137
Quickest round-trip

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Fri 10/2

2:24 pm-4:49 pm

Nonstop1h 25m

Knoxville McGhee Tyson

Fri 10/9

11:14 am-11:46 am

Nonstop1h 32m

$139

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Thu 7/9

2:48 pm-5:18 pm

Nonstop1h 30m

Knoxville McGhee Tyson

Sun 7/12

1:22 pm-1:58 pm

Nonstop1h 36m

$140

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Mon 10/12

1:26 pm-3:51 pm

Nonstop1h 25m

Knoxville McGhee Tyson

Fri 10/16

3:08 pm-3:40 pm

Nonstop1h 32m

$147

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Thu 5/21

2:47 pm-5:13 pm

Nonstop1h 26m

Knoxville McGhee Tyson

Sun 5/24

1:22 pm-1:57 pm

Nonstop1h 35m

$148

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Thu 6/18

2:46 pm-5:14 pm

Nonstop1h 28m

Knoxville McGhee Tyson

Sun 6/21

1:22 pm-1:56 pm

Nonstop1h 34m

$163

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Thu 5/28

2:47 pm-5:13 pm

Nonstop1h 26m

Knoxville McGhee Tyson

Mon 6/1

12:55 pm-11:12 am

2 stops23h 17m

$171

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Mon 5/25

9:30 pm-7:31 pm

1 stop21h 01m

Knoxville McGhee Tyson

Thu 5/28

1:22 pm-1:57 pm

Nonstop1h 35m

$172

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Sun 6/14

2:46 pm-5:14 pm

Nonstop1h 28m

Knoxville McGhee Tyson

Sun 6/21

1:22 pm-1:56 pm

Nonstop1h 34m

$174

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Thu 5/28

12:27 pm-4:40 pm

2 stops27h 13m

Knoxville McGhee Tyson

Sun 5/31

1:22 pm-1:57 pm

Nonstop1h 35m

$176

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Knoxville from

How to get the cheapest flight ticket from Chicago Midway Airport to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Chicago Midway Airport and Knoxville?

What is the cheapest month to fly to Knoxville?

The month of December is, on average, the cheapest month to fly to Knoxville from Chicago Midway Airport, with most prices found around $0. If you aren’t able to travel during the month of December, then book flights to Knoxville from Chicago Midway Airport during January instead. Flights to Knoxville in January, while not as cheap as those in December, still average around $0.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Chicago Midway Airport to Knoxville is on a Wednesday. Travelers who choose to depart for Knoxville on a Wednesday will often find tickets for as low as $274. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Chicago Midway Airport to Knoxville for around $318.

What is the cheapest time of day to depart on your flight to Knoxville?

At noon is the cheapest time of day to fly from Chicago Midway Airport to Knoxville when you can find flight prices for as low as $253. Flying to Knoxville at noon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the afternoon when prices are around $322.

What is the cheapest Chicago Midway to Knoxville McGhee Tyson flight route?

Fly from Chicago Midway to Knoxville McGhee Tyson for the best Chicago Midway - Knoxville McGhee Tyson flight prices

When to book flights from Chicago Midway Airport to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago Midway Airport to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago Midway Airport to Knoxville (MDW to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago Midway Airport to Knoxville

Best Price Found

$73

Fastest flight time

1h 25m

Direct flights

Mon, Tue, Fri and Sat

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from Chicago Midway Airport in the past 72 hours is $73. The best round-trip flight deal from Chicago Midway Airport to Knoxville found on momondo in the last 72 hours is $119.
The fastest flight from Chicago Midway Airport to Knoxville takes 1h 25m
Direct flights go from Chicago Midway Airport to Knoxville on Monday, Tuesday, Friday and Saturday. The only airline offering direct flights is Allegiant Air.
There is 1 airport in Knoxville. From Chicago Midway Airport there are direct flights to Knoxville McGhee Tyson (TYS).
Search flight deals

Frequently asked questions about flying from Chicago Midway Airport to Knoxville

  • How far is Chicago Midway to Knoxville McGhee Tyson by plane?

    There are 451.6 mi between Chicago Midway and Knoxville McGhee Tyson. Flights usually cover this in 1h 25m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Chicago Midway Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Chicago Midway Airport to Knoxville McGhee Tyson Airport refresh daily.

  • How many operators does momondo search for flights from Chicago Midway Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Chicago Midway Airport to Knoxville McGhee Tyson Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago Midway Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The necessary travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Chicago Midway Airport to Knoxville?

  • What is the most popular airline from Chicago Midway Airport to Knoxville?

Best airlines flying from Chicago Midway Airport to Knoxville

Compare and see reviews for airlines that fly from Chicago Midway Airport to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $61Free CancellationRating
7.3
707 reviews
Search Allegiant Air flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Alcoa
Crossville
Maryville
Murphy
Oak Ridge
Lenoir City
Newport
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Knoxville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Knoxville from Chicago.

Can I find flights from Chicago to Knoxville with flexible booking policies on momondo?

Yes. All flights to Knoxville from Chicago on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Chicago to Knoxville?

Once you have performed a search for Chicago to Knoxville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Chicago to Knoxville right now. Can momondo alert me if prices change?

Price alerts on flights to Knoxville from Chicago are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Knoxville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 6/3
Wed 6/10
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States