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Cheap flights from Knoxville to San Jose from $134

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to San Jose departing on 10/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to San Jose

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:30 am - 1:29 pmTYS  Knoxville McGhee Tyson-SJC San Jose
33h 59m2 stops Denver Intl Las Vegas Harry Reid Intl
Multiple Airlines Logo
2:24 pm - 10:35 pmSJC  San Jose-TYS Knoxville McGhee Tyson
29h 11m1 stop Las Vegas Harry Reid Intl
$267Multiple Airlines
Thu, Oct 29 - Thu, Nov 12
Multiple Airlines Logo
9:29 pm - 1:29 pmTYS  Knoxville McGhee Tyson-SJC San Jose
19h 00m1 stop Las Vegas Harry Reid Intl
Multiple Airlines Logo
2:24 pm - 10:35 pmSJC  San Jose-TYS Knoxville McGhee Tyson
29h 11m1 stop Las Vegas Harry Reid Intl
$295Multiple Airlines
Thu, Oct 29 - Thu, Nov 12
American Airlines Logo
6:00 am - 10:53 amTYS  Knoxville McGhee Tyson-SJC San Jose
7h 53m1 stop Dallas/Fort Worth
American Airlines Logo
12:02 pm - 11:22 pmSJC  San Jose-TYS Knoxville McGhee Tyson
8h 20m1 stop Dallas/Fort Worth
$318American Airlines
Tue, Sep 22 - Sat, Sep 26
American Airlines Logo
6:00 am - 11:04 amTYS  Knoxville McGhee Tyson-SJC San Jose
8h 04m1 stop Dallas/Fort Worth
American Airlines Logo
12:02 pm - 9:45 pmSJC  San Jose-TYS Knoxville McGhee Tyson
6h 43m1 stop Dallas/Fort Worth
$318American Airlines
Wed, Oct 7 - Sat, Oct 17
Southwest Logo
8:05 am - 6:20 pmTYS  Knoxville McGhee Tyson-SJC San Jose
13h 15m1 stop Baltimore/Washington
Southwest Logo
7:30 pm - 10:55 amSJC  San Jose-TYS Knoxville McGhee Tyson
12h 25m2 stops Las Vegas Harry Reid Intl Nashville Intl
$350Southwest
Tue, Sep 22 - Sat, Sep 26
American Airlines Logo
6:00 am - 11:04 amTYS  Knoxville McGhee Tyson-SJC San Jose
8h 04m1 stop Dallas/Fort Worth
American Airlines Logo
12:02 pm - 9:45 pmSJC  San Jose-TYS Knoxville McGhee Tyson
6h 43m1 stop Dallas/Fort Worth
$369American Airlines
Wed, Oct 7 - Sat, Oct 17
Southwest Logo
3:00 pm - 9:30 pmTYS  Knoxville McGhee Tyson-SJC San Jose
9h 30m2 stops Denver Intl Las Vegas Harry Reid Intl
Southwest Logo
8:40 am - 7:00 pmSJC  San Jose-TYS Knoxville McGhee Tyson
7h 20m1 stop Nashville Intl
$372Southwest
Wed, Sep 9 - Wed, Sep 16
Delta Logo
6:35 am - 12:27 pmTYS  Knoxville McGhee Tyson-SJC San Jose
8h 52m1 stop Minneapolis St Paul
Delta Logo
12:51 pm - 10:27 pmSJC  San Jose-TYS Knoxville McGhee Tyson
6h 36m1 stop Atlanta Hartsfield-Jackson
$387Delta
Wed, Sep 2 - Tue, Sep 8
Delta Logo
5:40 am - 11:44 amTYS  Knoxville McGhee Tyson-SJC San Jose
9h 04m1 stop Atlanta Hartsfield-Jackson
Delta Logo
5:42 pm - 10:16 amSJC  San Jose-TYS Knoxville McGhee Tyson
13h 34m2 stops Seattle/Tacoma Intl Detroit Metropolitan Wayne County
$395Delta
Wed, Oct 7 - Sat, Oct 17
Delta Logo
6:35 am - 12:27 pmTYS  Knoxville McGhee Tyson-SJC San Jose
8h 52m1 stop Minneapolis St Paul
Delta Logo
2:20 pm - 9:36 amSJC  San Jose-TYS Knoxville McGhee Tyson
16h 16m2 stops Los Angeles Atlanta Hartsfield-Jackson
$411Delta
Wed, Sep 2 - Sun, Sep 6

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Southwest flights from Knoxville to San Jose, California

Our best Southwest deals on Knoxville to San Jose, California flight tickets
Southwest
Sep 22
TYS8:05 amKnoxville McGhee Tyson
13h 15m
1 stop
SJC6:20 pmSan Jose
Sep 26
SJC7:30 pmSan Jose
12h 25m
2 stops
TYS10:55 amKnoxville McGhee Tyson
$350
Southwest
Sep 9
TYS3:00 pmKnoxville McGhee Tyson
9h 30m
2 stops
SJC9:30 pmSan Jose
Sep 16
SJC8:40 amSan Jose
7h 20m
1 stop
TYS7:00 pmKnoxville McGhee Tyson
$372
Southwest
Sep 9
TYS3:00 pmKnoxville McGhee Tyson
9h 45m
2 stops
SJC9:45 pmSan Jose
Sep 16
SJC6:40 amSan Jose
9h 20m
2 stops
TYS7:00 pmKnoxville McGhee Tyson
$377

Delta flights from Knoxville to San Jose, California

Our best Delta deals on Knoxville to San Jose, California flight tickets
Delta
Sep 2
TYS6:35 amKnoxville McGhee Tyson
8h 52m
1 stop
SJC12:27 pmSan Jose
Sep 8
SJC12:51 pmSan Jose
6h 36m
1 stop
TYS10:27 pmKnoxville McGhee Tyson
$387
Delta
Oct 7
TYS5:40 amKnoxville McGhee Tyson
9h 04m
1 stop
SJC11:44 amSan Jose
Oct 17
SJC5:42 pmSan Jose
13h 34m
2 stops
TYS10:16 amKnoxville McGhee Tyson
$395
Delta
Sep 2
TYS6:35 amKnoxville McGhee Tyson
8h 52m
1 stop
SJC12:27 pmSan Jose
Sep 6
SJC2:20 pmSan Jose
16h 16m
2 stops
TYS9:36 amKnoxville McGhee Tyson
$411

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to San Jose, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 12, 2026.
Use the filters below to find and compare flights from Knoxville to San Jose, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleSan Jose

TYS Knoxville McGhee Tyson - SJC San Jose

TYSSJC

Knoxville McGhee Tyson

Thu 10/29

6:30 am-1:29 pm

2 stops33h 59m

San Jose

Thu 11/12

2:24 pm-10:35 pm

1 stop29h 11m

$267

KnoxvilleSan Jose

TYS Knoxville McGhee Tyson - SJC San Jose

TYSSJC

Knoxville McGhee Tyson

Thu 10/29

9:29 pm-1:29 pm

1 stop19h 00m

San Jose

Thu 11/12

2:24 pm-10:35 pm

1 stop29h 11m

$295

KnoxvilleSan Jose

TYS Knoxville McGhee Tyson - SJC San Jose

TYSSJC

Knoxville McGhee Tyson

Tue 9/22

6:00 am-10:53 am

1 stop7h 53m

San Jose

Sat 9/26

12:02 pm-11:22 pm

1 stop8h 20m

$318
Quickest round-trip

KnoxvilleSan Jose

TYS Knoxville McGhee Tyson - SJC San Jose

TYSSJC

Knoxville McGhee Tyson

Wed 10/7

6:00 am-11:04 am

1 stop8h 04m

San Jose

Sat 10/17

12:02 pm-9:45 pm

1 stop6h 43m

$318

KnoxvilleSan Jose

TYS Knoxville McGhee Tyson - SJC San Jose

TYSSJC

Knoxville McGhee Tyson

Tue 9/22

8:05 am-6:20 pm

1 stop13h 15m

San Jose

Sat 9/26

7:30 pm-10:55 am

2 stops12h 25m

$350

KnoxvilleSan Jose

TYS Knoxville McGhee Tyson - SJC San Jose

TYSSJC

Knoxville McGhee Tyson

Wed 10/7

6:00 am-11:04 am

1 stop8h 04m

San Jose

Sat 10/17

12:02 pm-9:45 pm

1 stop6h 43m

$369

KnoxvilleSan Jose

TYS Knoxville McGhee Tyson - SJC San Jose

TYSSJC

Knoxville McGhee Tyson

Wed 9/9

3:00 pm-9:30 pm

2 stops9h 30m

San Jose

Wed 9/16

8:40 am-7:00 pm

1 stop7h 20m

$372

KnoxvilleSan Jose

TYS Knoxville McGhee Tyson - SJC San Jose

TYSSJC

Knoxville McGhee Tyson

Wed 9/2

6:35 am-12:27 pm

1 stop8h 52m

San Jose

Tue 9/8

12:51 pm-10:27 pm

1 stop6h 36m

$387

KnoxvilleSan Jose

TYS Knoxville McGhee Tyson - SJC San Jose

TYSSJC

Knoxville McGhee Tyson

Wed 10/7

5:40 am-11:44 am

1 stop9h 04m

San Jose

Sat 10/17

5:42 pm-10:16 am

2 stops13h 34m

$395

KnoxvilleSan Jose

TYS Knoxville McGhee Tyson - SJC San Jose

TYSSJC

Knoxville McGhee Tyson

Wed 9/2

6:35 am-12:27 pm

1 stop8h 52m

San Jose

Sun 9/6

2:20 pm-9:36 am

2 stops16h 16m

$411

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Jose from

How to get the cheapest flight ticket from Knoxville to San Jose, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Jose, California?

The month of September is, on average, the cheapest month to fly to San Jose, California from Knoxville, with most prices found around $414. If you are unable to visit San Jose, California during the month of September, then departing from Knoxville during the month August is also very affordable. Most momondo users find prices during this month for around $426.

Can stopping save me money on Knoxville to San Jose, California flights?

You could potentially save up to 48% on your flight if you consider stops on a Knoxville to San Jose, California flight.

How have Knoxville to San Jose, California flight prices changed over time?

When to book flights from Knoxville to San Jose, California

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to San Jose, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to San Jose, California (TYS to SJC) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to San Jose, California

Fastest flight time

7h 07m

Direct flights

None
The fastest flight from Knoxville to San Jose, California takes 7h 07m
There are no direct flights from Knoxville to San Jose, California. There are no popular flight routes from Knoxville to San Jose, California.
Search flight deals

Frequently asked questions about flying from Knoxville to San Jose, California

  • How far is Knoxville McGhee Tyson to San Jose by plane?

    Knoxville McGhee Tyson and San Jose are 2091.1 mi apart from one another. Flights usually cover this in 7h 07m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to San Jose Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to San Jose Airport are updated daily.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to San Jose Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to San Jose Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to San Jose Airport.

  • What documentation or ID do you need to fly to San Jose Airport?

    The required travel and health documents for your San Jose Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Jose Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Knoxville to San Jose, California?

Best airlines flying from Knoxville to San Jose, California

Compare and see reviews for airlines that fly from Knoxville to San Jose, California with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $260Free CancellationRating
7.1
11,911 reviews
Search American Airlines flights
DeltaPriceFrom $277Free CancellationRating
7.8
8,505 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to San Jose?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Knoxville to San Jose. momondo saves you time and could save you money on your trip.

Can I find flights from Knoxville to San Jose with flexible booking policies on momondo?

All flight searches from Knoxville to San Jose on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Knoxville to San Jose?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to San Jose from Knoxville.

I’m not ready to book a flight from Knoxville to San Jose right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Jose from Knoxville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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