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Cheap flights from Knoxville to McAllen from $367

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to McAllen departing on 6/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Knoxville to McAllen

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:36 am - 9:59 am
TYS
-
MFE
5h 23m
1 stop
American Airlines Logo
5:00 am - 1:03 pm
MFE
-
TYS
7h 03m
1 stop
$367American Airlines
Wed, Jun 3 - Wed, Jun 10
Delta Logo
5:30 am - 12:23 pm
TYS
-
MFE
7h 53m
2 stops
Delta Logo
12:48 pm - 11:46 pm
MFE
-
TYS
9h 58m
2 stops
$379Delta
Thu, Jun 11 - Mon, Jun 15
United Airlines Logo
7:15 am - 11:23 am
TYS
-
MFE
5h 08m
1 stop
United Airlines Logo
5:00 am - 11:17 am
MFE
-
TYS
5h 17m
1 stop
$391United Airlines
Wed, Aug 26 - Sat, Aug 29
United Airlines Logo
6:30 am - 3:59 pm
TYS
-
MFE
10h 29m
2 stops
United Airlines Logo
12:07 pm - 6:05 pm
MFE
-
TYS
4h 58m
1 stop
$396United Airlines
Wed, Aug 26 - Sat, Aug 29
United Airlines Logo
6:30 am - 3:59 pm
TYS
-
MFE
10h 29m
2 stops
United Airlines Logo
5:00 am - 4:59 pm
MFE
-
TYS
10h 59m
2 stops
$401United Airlines
Wed, Aug 26 - Sat, Aug 29
United Airlines Logo
7:15 am - 11:23 am
TYS
-
MFE
5h 08m
1 stop
United Airlines Logo
5:00 am - 4:59 pm
MFE
-
TYS
10h 59m
2 stops
$406United Airlines
Wed, Aug 26 - Sat, Aug 29
United Airlines Logo
7:15 am - 11:23 am
TYS
-
MFE
5h 08m
1 stop
United Airlines Logo
2:05 pm - 9:30 pm
MFE
-
TYS
6h 25m
1 stop
$411United Airlines
Wed, Aug 26 - Sat, Aug 29
United Airlines Logo
7:15 am - 11:23 am
TYS
-
MFE
5h 08m
1 stop
United Airlines Logo
5:00 am - 4:59 pm
MFE
-
TYS
10h 59m
2 stops
$416United Airlines
Wed, Aug 26 - Sat, Aug 29
American Airlines Logo
1:20 pm - 6:42 pm
TYS
-
MFE
6h 22m
1 stop
American Airlines Logo
3:45 pm - 11:56 pm
MFE
-
TYS
7h 11m
1 stop
$417American Airlines
Tue, Apr 7 - Wed, Apr 8
United Airlines Logo
6:30 am - 3:59 pm
TYS
-
MFE
10h 29m
2 stops
United Airlines Logo
9:38 am - 8:48 pm
MFE
-
TYS
10h 10m
2 stops
$421United Airlines
Wed, Aug 26 - Sat, Aug 29

American Airlines flights from Knoxville to McAllen

Our best American Airlines deals on Knoxville to McAllen flight tickets
American Airlines
Jun 3
TYS5:36 amKnoxville McGhee Tyson
5h 23m
1 stop
MFE9:59 amMcAllen Miller Intl
Jun 10
MFE5:00 amMcAllen Miller Intl
7h 03m
1 stop
TYS1:03 pmKnoxville McGhee Tyson
$367
American Airlines
Apr 7
TYS1:20 pmKnoxville McGhee Tyson
6h 22m
1 stop
MFE6:42 pmMcAllen Miller Intl
Apr 8
MFE3:45 pmMcAllen Miller Intl
7h 11m
1 stop
TYS11:56 pmKnoxville McGhee Tyson
$417
American Airlines
Apr 7
TYS8:16 amKnoxville McGhee Tyson
11h 26m
2 stops
MFE6:42 pmMcAllen Miller Intl
Apr 8
MFE3:45 pmMcAllen Miller Intl
7h 11m
1 stop
TYS11:56 pmKnoxville McGhee Tyson
$542

United Airlines flights from Knoxville to McAllen

Our best United Airlines deals on Knoxville to McAllen flight tickets
United Airlines
Aug 26
TYS7:15 amKnoxville McGhee Tyson
5h 08m
1 stop
MFE11:23 amMcAllen Miller Intl
Aug 29
MFE5:00 amMcAllen Miller Intl
5h 17m
1 stop
TYS11:17 amKnoxville McGhee Tyson
$391
United Airlines
Aug 26
TYS6:30 amKnoxville McGhee Tyson
10h 29m
2 stops
MFE3:59 pmMcAllen Miller Intl
Aug 29
MFE12:07 pmMcAllen Miller Intl
4h 58m
1 stop
TYS6:05 pmKnoxville McGhee Tyson
$396
United Airlines
Aug 26
TYS6:30 amKnoxville McGhee Tyson
10h 29m
2 stops
MFE3:59 pmMcAllen Miller Intl
Aug 29
MFE5:00 amMcAllen Miller Intl
10h 59m
2 stops
TYS4:59 pmKnoxville McGhee Tyson
$401

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to McAllen that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 20, 2026.
Use the filters below to find and compare flights from Knoxville to McAllen that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleMcAllen

TYS - MFE

TYSMFE

Knoxville McGhee Tyson

Wed 6/3

5:36 am-9:59 am

1 stop5h 23m

McAllen Miller Intl

Wed 6/10

5:00 am-1:03 pm

1 stop7h 03m

$367

KnoxvilleMcAllen

TYS - MFE

TYSMFE

Knoxville McGhee Tyson

Thu 6/11

5:30 am-12:23 pm

2 stops7h 53m

McAllen Miller Intl

Mon 6/15

12:48 pm-11:46 pm

2 stops9h 58m

$379
Quickest round-trip

KnoxvilleMcAllen

TYS - MFE

TYSMFE

Knoxville McGhee Tyson

Wed 8/26

7:15 am-11:23 am

1 stop5h 08m

McAllen Miller Intl

Sat 8/29

5:00 am-11:17 am

1 stop5h 17m

$391

KnoxvilleMcAllen

TYS - MFE

TYSMFE

Knoxville McGhee Tyson

Wed 8/26

6:30 am-3:59 pm

2 stops10h 29m

McAllen Miller Intl

Sat 8/29

12:07 pm-6:05 pm

1 stop4h 58m

$396

KnoxvilleMcAllen

TYS - MFE

TYSMFE

Knoxville McGhee Tyson

Wed 8/26

6:30 am-3:59 pm

2 stops10h 29m

McAllen Miller Intl

Sat 8/29

5:00 am-4:59 pm

2 stops10h 59m

$401

KnoxvilleMcAllen

TYS - MFE

TYSMFE

Knoxville McGhee Tyson

Wed 8/26

7:15 am-11:23 am

1 stop5h 08m

McAllen Miller Intl

Sat 8/29

5:00 am-4:59 pm

2 stops10h 59m

$406

KnoxvilleMcAllen

TYS - MFE

TYSMFE

Knoxville McGhee Tyson

Wed 8/26

7:15 am-11:23 am

1 stop5h 08m

McAllen Miller Intl

Sat 8/29

2:05 pm-9:30 pm

1 stop6h 25m

$411

KnoxvilleMcAllen

TYS - MFE

TYSMFE

Knoxville McGhee Tyson

Wed 8/26

7:15 am-11:23 am

1 stop5h 08m

McAllen Miller Intl

Sat 8/29

5:00 am-4:59 pm

2 stops10h 59m

$416

KnoxvilleMcAllen

TYS - MFE

TYSMFE

Knoxville McGhee Tyson

Tue 4/7

1:20 pm-6:42 pm

1 stop6h 22m

McAllen Miller Intl

Wed 4/8

3:45 pm-11:56 pm

1 stop7h 11m

$417

KnoxvilleMcAllen

TYS - MFE

TYSMFE

Knoxville McGhee Tyson

Wed 8/26

6:30 am-3:59 pm

2 stops10h 29m

McAllen Miller Intl

Sat 8/29

9:38 am-8:48 pm

2 stops10h 10m

$421

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to McAllen from

How to get the cheapest flight ticket from Knoxville to McAllen

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Knoxville to McAllen flights?

You could potentially save up to 49% on your flight if you consider stops on a Knoxville to McAllen flight.

When to book flights from Knoxville to McAllen

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to McAllen according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to McAllen (TYS to MFE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to McAllen

Fastest flight time

5h 33m

Direct flights

None
The fastest flight from Knoxville to McAllen takes 5h 33m
There are no direct flights from Knoxville to McAllen. There are no popular flight routes from Knoxville to McAllen.
Search flight deals

  • How far is Knoxville McGhee Tyson to McAllen Miller Intl by plane?

    Knoxville McGhee Tyson and McAllen Miller Intl are 1079.4 mi apart from one another. A reasonable flight in good conditions will take 5h 33m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to McAllen Miller Intl Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to McAllen Miller Intl Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to McAllen Miller Intl Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to McAllen Miller Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to McAllen Miller Intl Airport.

  • What documentation or ID do you need to fly to McAllen Miller Intl Airport?

    The travel and health documents you'll need for your trip to McAllen Miller Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at McAllen Miller Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Knoxville to McAllen?

Best airlines flying from Knoxville to McAllen

Compare and see reviews for airlines that fly from Knoxville to McAllen with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $278Free CancellationRating
7.1
11,481 reviews
Search American Airlines flights

Traveling to a place near McAllen?

Book flights to McAllen if you plan to visit one of these locations
Weslaco
Pharr
Mission
Edinburg

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to McAllen?

It is quick and easy to find Knoxville to McAllen flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to McAllen that suits you.

Can I find flights from Knoxville to McAllen with flexible booking policies on momondo?

momondo does allow users to show only those flights to McAllen from Knoxville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Knoxville to McAllen?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to McAllen from Knoxville.

I’m not ready to book a flight from Knoxville to McAllen right now. Can momondo alert me if prices change?

If you are simply researching potential flights to McAllen, momondo offers a useful price alert feature which will track prices for flights to McAllen from Knoxville and alert you when they change.

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