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Cheap flights from Knoxville to McAllen from $324

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to McAllen departing on 12/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Knoxville to McAllen

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:45 am - 4:07 pm
TYS
-
MFE
10h 22m2 stops
United Airlines Logo
5:25 pm - 11:44 pm
MFE
-
TYS
5h 19m1 stop
$443United Airlines
lun., ene. 12 - mié., ene. 14
United Airlines Logo
6:45 am - 4:07 pm
TYS
-
MFE
10h 22m2 stops
United Airlines Logo
7:00 am - 8:52 pm
MFE
-
TYS
12h 52m2 stops
$448United Airlines
lun., ene. 12 - mié., ene. 14
United Airlines Logo
11:40 am - 4:07 pm
TYS
-
MFE
5h 27m1 stop
United Airlines Logo
7:00 am - 1:50 pm
MFE
-
TYS
5h 50m1 stop
$477United Airlines
lun., ene. 12 - mié., ene. 14
United Airlines Logo
6:45 am - 4:07 pm
TYS
-
MFE
10h 22m2 stops
United Airlines Logo
5:25 pm - 11:44 pm
MFE
-
TYS
5h 19m1 stop
$482United Airlines
lun., ene. 12 - mié., ene. 14
United Airlines Logo
6:45 am - 4:07 pm
TYS
-
MFE
10h 22m2 stops
United Airlines Logo
7:00 am - 8:52 pm
MFE
-
TYS
12h 52m2 stops
$487United Airlines
lun., ene. 12 - mié., ene. 14

United Airlines flights from Knoxville to McAllen

Our best United Airlines deals on Knoxville to McAllen flight tickets
United Airlines
Jan 17
TYS4:55 pmKnoxville McGhee Tyson
6h 02m
1 stop
MFE9:57 pmMcAllen Miller Intl
Jan 24
MFE5:25 pmMcAllen Miller Intl
5h 19m
1 stop
TYS11:44 pmKnoxville McGhee Tyson
$319
Find similar
United Airlines
Jan 17
TYS4:55 pmKnoxville McGhee Tyson
6h 02m
1 stop
MFE9:57 pmMcAllen Miller Intl
Jan 24
MFE9:30 amMcAllen Miller Intl
10h 22m
2 stops
TYS8:52 pmKnoxville McGhee Tyson
$324
Find similar
United Airlines
Jan 12
TYS6:45 amKnoxville McGhee Tyson
10h 22m
2 stops
MFE4:07 pmMcAllen Miller Intl
Jan 14
MFE5:25 pmMcAllen Miller Intl
5h 19m
1 stop
TYS11:44 pmKnoxville McGhee Tyson
$443
Find similar

Delta flights from Knoxville to McAllen

Our best Delta deals on Knoxville to McAllen flight tickets
Delta
Jan 17
TYS5:40 amKnoxville McGhee Tyson
7h 40m
2 stops
MFE12:20 pmMcAllen Miller Intl
Jan 24
MFE5:25 amMcAllen Miller Intl
8h 54m
2 stops
TYS3:19 pmKnoxville McGhee Tyson
$294
Find similar
Delta
Dec 21
TYS6:00 amKnoxville McGhee Tyson
11h 35m
2 stops
MFE4:35 pmMcAllen Miller Intl
Dec 29
MFE5:25 amMcAllen Miller Intl
9h 26m
2 stops
TYS3:51 pmKnoxville McGhee Tyson
$698
Find similar
Delta
Dec 21
TYS6:00 amKnoxville McGhee Tyson
11h 35m
2 stops
MFE4:35 pmMcAllen Miller Intl
Dec 27
MFE5:25 amMcAllen Miller Intl
9h 26m
2 stops
TYS3:51 pmKnoxville McGhee Tyson
$878
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to McAllen that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated diciembre 16, 2025.
Use the filters below to find and compare flights from Knoxville to McAllen that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleMcAllen

TYS - MFE

TYSMFE

Knoxville McGhee Tyson

lun. 1/12

6:45 am-4:07 pm

2 stops10h 22m

McAllen Miller Intl

mié. 1/14

5:25 pm-11:44 pm

1 stop5h 19m

$443

KnoxvilleMcAllen

TYS - MFE

TYSMFE

Knoxville McGhee Tyson

lun. 1/12

6:45 am-4:07 pm

2 stops10h 22m

McAllen Miller Intl

mié. 1/14

7:00 am-8:52 pm

2 stops12h 52m

$448

KnoxvilleMcAllen

TYS - MFE

TYSMFE

Knoxville McGhee Tyson

lun. 1/12

11:40 am-4:07 pm

1 stop5h 27m

McAllen Miller Intl

mié. 1/14

7:00 am-1:50 pm

1 stop5h 50m

$477

KnoxvilleMcAllen

TYS - MFE

TYSMFE

Knoxville McGhee Tyson

lun. 1/12

6:45 am-4:07 pm

2 stops10h 22m

McAllen Miller Intl

mié. 1/14

5:25 pm-11:44 pm

1 stop5h 19m

$482

KnoxvilleMcAllen

TYS - MFE

TYSMFE

Knoxville McGhee Tyson

lun. 1/12

6:45 am-4:07 pm

2 stops10h 22m

McAllen Miller Intl

mié. 1/14

7:00 am-8:52 pm

2 stops12h 52m

$487

KnoxvilleMcAllen

TYS - MFE

TYSMFE

Knoxville McGhee Tyson

lun. 12/22

4:29 pm-10:59 pm

1 stop7h 30m

$324

KnoxvilleMcAllen

TYS - MFE

TYSMFE

Knoxville McGhee Tyson

lun. 12/22

6:45 am-5:50 pm

2 stops12h 05m

$329

KnoxvilleMcAllen

TYS - MFE

TYSMFE

Knoxville McGhee Tyson

sáb. 12/20

5:15 pm-11:25 pm

1 stop7h 10m

$352

KnoxvilleMcAllen

TYS - MFE

TYSMFE

Knoxville McGhee Tyson

sáb. 12/20

4:31 pm-11:58 pm

2 stops8h 27m

$422

KnoxvilleMcAllen

TYS - MFE

TYSMFE

Knoxville McGhee Tyson

lun. 12/22

5:38 pm-7:22 pm

3 stops50h 44m

$426

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 11 resultsSorted by cheapest first
1
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See travel insights to McAllen from

How to get the cheapest flight ticket from Knoxville to McAllen

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to McAllen?

On average, the least expensive day to fly to McAllen from Knoxville is on a Wednesday. momondo users have found tickets for Wednesday departures for as low as $258. However, this price may fluctuate depending on the airline, the season, and holidays. When flying out on a Thursday, the most expensive travel day of the week, you can expect to see flight prices from Knoxville to McAllen for around $317.

What is the cheapest time of day to depart on your flight to McAllen?

Flying to McAllen from Knoxville in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $265 when looking at flights departing in the afternoon. In contrast, the most expensive time of day to depart to McAllen is in the morning when prices are around $353.

Can stopping save me money on Knoxville to McAllen flights?

You could potentially save up to 8% on your flight if you consider stops on a Knoxville to McAllen flight.

When to book flights from Knoxville to McAllen

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to McAllen according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to McAllen (TYS to MFE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to McAllen

Fastest flight time

5h 27m

Direct flights

None
The fastest flight from Knoxville to McAllen takes 5h 27m
There are no direct flights from Knoxville to McAllen. There are no popular flight routes from Knoxville to McAllen.
Search flight deals

  • How far is Knoxville McGhee Tyson to McAllen Miller Intl by plane?

    Knoxville McGhee Tyson and McAllen Miller Intl are 1079.4 mi apart from one another. A reasonable flight in good conditions will take 5h 27m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to McAllen Miller Intl Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to McAllen Miller Intl Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to McAllen Miller Intl Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to McAllen Miller Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to McAllen Miller Intl Airport.

  • What documentation or ID do you need to fly to McAllen Miller Intl Airport?

    The travel and health documents you'll need for your trip to McAllen Miller Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at McAllen Miller Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Knoxville to McAllen?

Best airlines flying from Knoxville to McAllen

Compare and see reviews for airlines that fly from Knoxville to McAllen with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $253Free CancellationRating
7.2
11,049 reviews
Search American Airlines flights

Traveling to a place near McAllen?

Book flights to McAllen if you plan to visit one of these locations
Weslaco
Pharr
Mission
Edinburg

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to McAllen?

It is quick and easy to find Knoxville to McAllen flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to McAllen that suits you.

Can I find flights from Knoxville to McAllen with flexible booking policies on momondo?

momondo does allow users to show only those flights to McAllen from Knoxville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Knoxville to McAllen?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to McAllen from Knoxville.

I’m not ready to book a flight from Knoxville to McAllen right now. Can momondo alert me if prices change?

If you are simply researching potential flights to McAllen, momondo offers a useful price alert feature which will track prices for flights to McAllen from Knoxville and alert you when they change.

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