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Cheap flights from Knoxville to Medford from $365

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Medford departing on 5/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Knoxville to Medford

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
5:24 pm - 11:52 pm
TYS
-
MFR
9h 28m
2 stops
Delta Logo
5:21 pm - 9:11 am
MFR
-
TYS
12h 50m
2 stops
$365Delta
Fri, May 1 - Fri, May 8
Delta Logo
5:24 pm - 11:52 pm
TYS
-
MFR
9h 28m
2 stops
Delta Logo
5:21 pm - 9:11 am
MFR
-
TYS
12h 50m
2 stops
$400Delta
Fri, May 1 - Fri, May 8
Delta Logo
11:02 am - 11:30 pm
TYS
-
MFR
15h 28m
2 stops
Delta Logo
5:21 pm - 9:11 am
MFR
-
TYS
12h 50m
2 stops
$413Delta
Tue, May 5 - Wed, May 13
United Airlines Logo
8:45 am - 1:01 pm
TYS
-
MFR
7h 16m
1 stop
United Airlines Logo
6:36 pm - 10:06 am
MFR
-
TYS
12h 30m
2 stops
$434United Airlines
Fri, May 1 - Fri, May 8
United Airlines Logo
4:20 pm - 9:31 pm
TYS
-
MFR
8h 11m
1 stop
United Airlines Logo
6:36 pm - 10:06 am
MFR
-
TYS
12h 30m
2 stops
$464United Airlines
Fri, May 1 - Fri, May 8
United Airlines Logo
8:45 am - 1:01 pm
TYS
-
MFR
7h 16m
1 stop
United Airlines Logo
5:00 am - 10:23 pm
MFR
-
TYS
14h 23m
1 stop
$513United Airlines
Fri, May 1 - Fri, May 8
United Airlines Logo
4:20 pm - 9:31 pm
TYS
-
MFR
8h 11m
1 stop
United Airlines Logo
5:00 am - 10:23 pm
MFR
-
TYS
14h 23m
1 stop
$543United Airlines
Fri, May 1 - Fri, May 8
United Airlines Logo
9:40 am - 11:47 am
TYS
-
MFR
29h 07m
2 stops
United Airlines Logo
12:52 pm - 10:23 pm
MFR
-
TYS
6h 31m
1 stop
$632United Airlines
Tue, May 5 - Wed, May 13
United Airlines Logo
7:00 am - 5:55 pm
TYS
-
MFR
13h 55m
2 stops
United Airlines Logo
2:07 pm - 6:11 pm
MFR
-
TYS
25h 04m
3 stops
$640United Airlines
Fri, May 1 - Fri, May 8
United Airlines Logo
4:20 pm - 9:31 pm
TYS
-
MFR
8h 11m
1 stop
United Airlines Logo
12:52 pm - 10:23 pm
MFR
-
TYS
6h 31m
1 stop
$648United Airlines
Tue, May 5 - Wed, May 13

Delta flights from Knoxville to Medford

Our best Delta deals on Knoxville to Medford flight tickets
Delta
May 1
TYS5:24 pmKnoxville McGhee Tyson
9h 28m
2 stops
MFR11:52 pmMedford
May 8
MFR5:21 pmMedford
12h 50m
2 stops
TYS9:11 amKnoxville McGhee Tyson
$365
Delta
May 1
TYS5:24 pmKnoxville McGhee Tyson
9h 28m
2 stops
MFR11:52 pmMedford
May 8
MFR5:21 pmMedford
12h 50m
2 stops
TYS9:11 amKnoxville McGhee Tyson
$400
Delta
May 5
TYS11:02 amKnoxville McGhee Tyson
15h 28m
2 stops
MFR11:30 pmMedford
May 13
MFR5:21 pmMedford
12h 50m
2 stops
TYS9:11 amKnoxville McGhee Tyson
$413

United Airlines flights from Knoxville to Medford

Our best United Airlines deals on Knoxville to Medford flight tickets
United Airlines
May 1
TYS8:45 amKnoxville McGhee Tyson
7h 16m
1 stop
MFR1:01 pmMedford
May 8
MFR6:36 pmMedford
12h 30m
2 stops
TYS10:06 amKnoxville McGhee Tyson
$434
United Airlines
May 1
TYS4:20 pmKnoxville McGhee Tyson
8h 11m
1 stop
MFR9:31 pmMedford
May 8
MFR6:36 pmMedford
12h 30m
2 stops
TYS10:06 amKnoxville McGhee Tyson
$464
United Airlines
Feb 6
TYS4:25 pmKnoxville McGhee Tyson
7h 37m
1 stop
MFR9:02 pmMedford
Feb 8
MFR5:00 amMedford
7h 14m
1 stop
TYS3:14 pmKnoxville McGhee Tyson
$489

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Medford that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Knoxville to Medford that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Fri 5/1

5:24 pm-11:52 pm

2 stops9h 28m

Medford

Fri 5/8

5:21 pm-9:11 am

2 stops12h 50m

$365

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Fri 5/1

5:24 pm-11:52 pm

2 stops9h 28m

Medford

Fri 5/8

5:21 pm-9:11 am

2 stops12h 50m

$400

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Tue 5/5

11:02 am-11:30 pm

2 stops15h 28m

Medford

Wed 5/13

5:21 pm-9:11 am

2 stops12h 50m

$413

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Fri 5/1

8:45 am-1:01 pm

1 stop7h 16m

Medford

Fri 5/8

6:36 pm-10:06 am

2 stops12h 30m

$434

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Fri 5/1

4:20 pm-9:31 pm

1 stop8h 11m

Medford

Fri 5/8

6:36 pm-10:06 am

2 stops12h 30m

$464

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Fri 5/1

8:45 am-1:01 pm

1 stop7h 16m

Medford

Fri 5/8

5:00 am-10:23 pm

1 stop14h 23m

$513

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Fri 5/1

4:20 pm-9:31 pm

1 stop8h 11m

Medford

Fri 5/8

5:00 am-10:23 pm

1 stop14h 23m

$543

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Tue 5/5

9:40 am-11:47 am

2 stops29h 07m

Medford

Wed 5/13

12:52 pm-10:23 pm

1 stop6h 31m

$632

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Fri 5/1

7:00 am-5:55 pm

2 stops13h 55m

Medford

Fri 5/8

2:07 pm-6:11 pm

3 stops25h 04m

$640

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Tue 5/5

4:20 pm-9:31 pm

1 stop8h 11m

Medford

Wed 5/13

12:52 pm-10:23 pm

1 stop6h 31m

$648

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Medford from

How to get the cheapest flight ticket from Knoxville to Medford

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Knoxville to Medford flights?

You could potentially save up to 15% on your flight if you consider stops on a Knoxville to Medford flight.

When to book flights from Knoxville to Medford

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Medford according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Medford (TYS to MFR) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Medford

Fastest flight time

7h 34m

Direct flights

None
The fastest flight from Knoxville to Medford takes 7h 34m
There are no direct flights from Knoxville to Medford. There are no popular flight routes from Knoxville to Medford.
Search flight deals

  • How far is Knoxville McGhee Tyson to Medford by plane?

    Medford is 2112.6 mi away from Knoxville McGhee Tyson. In terms of flight time, this usually takes a little over 7h 34m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Medford Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Medford Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Medford Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Medford Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Medford Airport.

  • What documentation or ID do you need to fly to Medford Airport?

    The travel and health documents you'll need for your trip to Medford Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Medford Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Knoxville to Medford?

Best airlines flying from Knoxville to Medford

Compare and see reviews for airlines that fly from Knoxville to Medford with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $354Free CancellationRating
7.4
9,215 reviews
Search United Airlines flights

Traveling to a place near Medford?

Book flights to Medford if you plan to visit one of these locations
Grants Pass
Ashland
Yreka
Canyonville

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Medford?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to Medford. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Knoxville to Medford with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Knoxville to Medford flights to just show those with flexible booking policies.

How can momondo help me find flights from Knoxville to Medford?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Knoxville to Medford.

I’m not ready to book a flight from Knoxville to Medford right now. Can momondo alert me if prices change?

Price alerts on flights to Medford from Knoxville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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