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Cheap flights from Knoxville to Medford from $216

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Medford departing on 6/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Knoxville to Medford

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:15 pm - 11:55 pm
TYS
-
MFR
8h 40m
2 stops
Delta Logo
5:21 pm - 9:11 am
MFR
-
TYS
12h 50m
2 stops
$450Delta
Fri, Aug 28 - Sat, Sep 5
Allegiant Air Logo
5:56 pm - 8:41 pm
TYS
-
MFR
29h 45m
2 stops
Allegiant Air Logo
9:33 pm - 1:57 pm
MFR
-
TYS
13h 24m
1 stop
$485Allegiant Air
Sat, Jun 13 - Thu, Jul 16
Allegiant Air Logo
5:56 pm - 8:41 pm
TYS
-
MFR
29h 45m
2 stops
Allegiant Air Logo
9:33 pm - 1:57 pm
MFR
-
TYS
13h 24m
1 stop
$486Allegiant Air
Sat, Jun 13 - Sun, Jul 19
Delta Logo
6:15 pm - 11:55 pm
TYS
-
MFR
8h 40m
2 stops
Delta Logo
6:01 am - 8:10 pm
MFR
-
TYS
11h 09m
2 stops
$488Delta
Wed, Aug 12 - Thu, Aug 20
Multiple Airlines Logo
7:01 pm - 2:49 pm
TYS
-
MFR
22h 48m
2 stops
Multiple Airlines Logo
9:33 pm - 1:57 pm
MFR
-
TYS
13h 24m
1 stop
$509Multiple Airlines
Sun, Jun 14 - Thu, Jul 16
Multiple Airlines Logo
8:32 pm - 8:41 pm
TYS
-
MFR
27h 09m
2 stops
Multiple Airlines Logo
9:33 pm - 1:57 pm
MFR
-
TYS
13h 24m
1 stop
$510Multiple Airlines
Wed, Jun 17 - Thu, Jul 16
Multiple Airlines Logo
8:32 pm - 8:41 pm
TYS
-
MFR
27h 09m
2 stops
Multiple Airlines Logo
9:33 pm - 1:57 pm
MFR
-
TYS
13h 24m
1 stop
$511Multiple Airlines
Wed, Jun 17 - Sun, Jul 19
Delta Logo
5:45 am - 12:58 pm
TYS
-
MFR
10h 13m
2 stops
Delta Logo
6:01 am - 8:10 pm
MFR
-
TYS
11h 09m
2 stops
$521Delta
Wed, Aug 12 - Thu, Aug 20
Delta Logo
6:45 am - 4:44 pm
TYS
-
MFR
12h 59m
2 stops
Delta Logo
5:29 pm - 9:36 am
MFR
-
TYS
13h 07m
2 stops
$531Delta
Wed, Jun 17 - Thu, Jul 16
United Airlines Logo
4:56 pm - 9:16 pm
TYS
-
MFR
7h 20m
1 stop
United Airlines Logo
1:08 pm - 10:38 pm
MFR
-
TYS
6h 30m
1 stop
$559United Airlines
Wed, Aug 12 - Thu, Aug 20

Delta flights from Knoxville to Medford

Our best Delta deals on Knoxville to Medford flight tickets
Delta
Aug 28
TYS6:15 pmKnoxville McGhee Tyson
8h 40m
2 stops
MFR11:55 pmMedford
Sep 5
MFR5:21 pmMedford
12h 50m
2 stops
TYS9:11 amKnoxville McGhee Tyson
$450
Delta
Aug 12
TYS6:15 pmKnoxville McGhee Tyson
8h 40m
2 stops
MFR11:55 pmMedford
Aug 20
MFR6:01 amMedford
11h 09m
2 stops
TYS8:10 pmKnoxville McGhee Tyson
$488
Delta
Aug 12
TYS5:45 amKnoxville McGhee Tyson
10h 13m
2 stops
MFR12:58 pmMedford
Aug 20
MFR6:01 amMedford
11h 09m
2 stops
TYS8:10 pmKnoxville McGhee Tyson
$521

Alaska Airlines flights from Knoxville to Medford

Our best Alaska Airlines deals on Knoxville to Medford flight tickets
Alaska Airlines
Aug 12
TYS1:46 pmKnoxville McGhee Tyson
12h 13m
2 stops
MFR10:59 pmMedford
Aug 20
MFR6:00 amMedford
14h 18m
2 stops
TYS11:18 pmKnoxville McGhee Tyson
$569
Alaska Airlines
Jun 9
TYS1:13 pmKnoxville McGhee Tyson
13h 46m
2 stops
MFR11:59 pmMedford
Jun 29
MFR7:35 pmMedford
12h 23m
2 stops
TYS10:58 amKnoxville McGhee Tyson
$601
Alaska Airlines
Jun 9
TYS1:13 pmKnoxville McGhee Tyson
13h 46m
2 stops
MFR11:59 pmMedford
Jul 2
MFR7:50 pmMedford
12h 23m
2 stops
TYS11:13 amKnoxville McGhee Tyson
$631

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Medford that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 7, 2026.
Use the filters below to find and compare flights from Knoxville to Medford that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Fri 8/28

6:15 pm-11:55 pm

2 stops8h 40m

Medford

Sat 9/5

5:21 pm-9:11 am

2 stops12h 50m

$450

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Sat 6/13

5:56 pm-8:41 pm

2 stops29h 45m

Medford

Thu 7/16

9:33 pm-1:57 pm

1 stop13h 24m

$485

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Sat 6/13

5:56 pm-8:41 pm

2 stops29h 45m

Medford

Sun 7/19

9:33 pm-1:57 pm

1 stop13h 24m

$486

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Wed 8/12

6:15 pm-11:55 pm

2 stops8h 40m

Medford

Thu 8/20

6:01 am-8:10 pm

2 stops11h 09m

$488

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Sun 6/14

7:01 pm-2:49 pm

2 stops22h 48m

Medford

Thu 7/16

9:33 pm-1:57 pm

1 stop13h 24m

$509

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Wed 6/17

8:32 pm-8:41 pm

2 stops27h 09m

Medford

Thu 7/16

9:33 pm-1:57 pm

1 stop13h 24m

$510

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Wed 6/17

8:32 pm-8:41 pm

2 stops27h 09m

Medford

Sun 7/19

9:33 pm-1:57 pm

1 stop13h 24m

$511

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Wed 8/12

5:45 am-12:58 pm

2 stops10h 13m

Medford

Thu 8/20

6:01 am-8:10 pm

2 stops11h 09m

$521

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Wed 6/17

6:45 am-4:44 pm

2 stops12h 59m

Medford

Thu 7/16

5:29 pm-9:36 am

2 stops13h 07m

$531
Quickest round-trip

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Wed 8/12

4:56 pm-9:16 pm

1 stop7h 20m

Medford

Thu 8/20

1:08 pm-10:38 pm

1 stop6h 30m

$559

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Knoxville to Medford

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Knoxville to Medford flights?

You could potentially save up to 15% on your flight if you consider stops on a Knoxville to Medford flight.

When to book flights from Knoxville to Medford

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Medford according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Medford (TYS to MFR) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Medford

Fastest flight time

8h 40m

Direct flights

None
The fastest flight from Knoxville to Medford takes 8h 40m
There are no direct flights from Knoxville to Medford. There are no popular flight routes from Knoxville to Medford.
Search flight deals

Frequently asked questions about flying from Knoxville to Medford

  • How far is Knoxville McGhee Tyson to Medford by plane?

    Medford is 2112.6 mi away from Knoxville McGhee Tyson. In terms of flight time, this usually takes a little over 8h 40m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Medford Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Medford Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Medford Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Medford Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Medford Airport.

  • What documentation or ID do you need to fly to Medford Airport?

    The travel and health documents you'll need for your trip to Medford Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Medford Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Knoxville to Medford?

Best airlines flying from Knoxville to Medford

Compare and see reviews for airlines that fly from Knoxville to Medford with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $323Free CancellationRating
7.4
9,690 reviews
Search United Airlines flights

Traveling to a place near Medford?

Book flights to Medford if you plan to visit one of these locations
Grants Pass
Ashland
Yreka
Canyonville

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Medford?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to Medford. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Knoxville to Medford with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Knoxville to Medford flights to just show those with flexible booking policies.

How can momondo help me find flights from Knoxville to Medford?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Knoxville to Medford.

I’m not ready to book a flight from Knoxville to Medford right now. Can momondo alert me if prices change?

Price alerts on flights to Medford from Knoxville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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