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Cheap flights from Knoxville to Medford from $238

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Medford departing on 7/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Knoxville to Medford

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
4:30 pm - 9:37 pm
TYS
-
MFR
8h 07m
1 stop
United Airlines Logo
5:00 am - 3:06 pm
MFR
-
TYS
7h 06m
1 stop
$377United Airlines
Tue, Apr 21 - Tue, Apr 28
United Airlines Logo
4:30 pm - 9:37 pm
TYS
-
MFR
8h 07m
1 stop
United Airlines Logo
6:31 pm - 10:50 am
MFR
-
TYS
13h 19m
2 stops
$382United Airlines
Tue, Apr 21 - Tue, Apr 28
United Airlines Logo
2:25 pm - 11:14 pm
TYS
-
MFR
11h 49m
2 stops
United Airlines Logo
6:31 pm - 10:08 am
MFR
-
TYS
12h 37m
2 stops
$387United Airlines
Tue, Apr 21 - Tue, Apr 28
United Airlines Logo
4:20 pm - 9:31 pm
TYS
-
MFR
8h 11m
1 stop
United Airlines Logo
5:00 am - 4:51 pm
MFR
-
TYS
8h 51m
2 stops
$458United Airlines
Wed, May 6 - Sat, May 30
Delta Logo
6:15 pm - 11:41 pm
TYS
-
MFR
8h 26m
2 stops
Delta Logo
5:21 pm - 10:10 am
MFR
-
TYS
13h 49m
2 stops
$463Delta
Wed, Aug 12 - Thu, Aug 20
United Airlines Logo
4:56 pm - 9:16 pm
TYS
-
MFR
7h 20m
1 stop
United Airlines Logo
1:08 pm - 10:38 pm
MFR
-
TYS
6h 30m
1 stop
$473United Airlines
Wed, Aug 12 - Thu, Aug 20
Delta Logo
11:02 am - 11:20 pm
TYS
-
MFR
15h 18m
2 stops
Delta Logo
5:25 pm - 11:09 am
MFR
-
TYS
14h 44m
2 stops
$478Delta
Fri, May 1 - Fri, May 8
Delta Logo
6:15 pm - 11:41 pm
TYS
-
MFR
8h 26m
2 stops
Delta Logo
5:21 pm - 10:10 am
MFR
-
TYS
13h 49m
2 stops
$482Delta
Wed, Aug 12 - Thu, Aug 20
United Airlines Logo
4:56 pm - 9:16 pm
TYS
-
MFR
7h 20m
1 stop
United Airlines Logo
1:08 pm - 10:38 pm
MFR
-
TYS
6h 30m
1 stop
$483United Airlines
Wed, Aug 12 - Thu, Aug 20
Delta Logo
5:54 pm - 11:52 pm
TYS
-
MFR
8h 58m
2 stops
Delta Logo
5:25 pm - 9:34 am
MFR
-
TYS
13h 09m
2 stops
$488Delta
Fri, May 1 - Fri, May 8

Delta flights from Knoxville to Medford

Our best Delta deals on Knoxville to Medford flight tickets
Delta
Aug 12
TYS6:15 pmKnoxville McGhee Tyson
8h 26m
2 stops
MFR11:41 pmMedford
Aug 20
MFR5:21 pmMedford
13h 49m
2 stops
TYS10:10 amKnoxville McGhee Tyson
$463
Delta
May 1
TYS11:02 amKnoxville McGhee Tyson
15h 18m
2 stops
MFR11:20 pmMedford
May 8
MFR5:25 pmMedford
14h 44m
2 stops
TYS11:09 amKnoxville McGhee Tyson
$478
Delta
Aug 12
TYS6:15 pmKnoxville McGhee Tyson
8h 26m
2 stops
MFR11:41 pmMedford
Aug 20
MFR5:21 pmMedford
13h 49m
2 stops
TYS10:10 amKnoxville McGhee Tyson
$482

United Airlines flights from Knoxville to Medford

Our best United Airlines deals on Knoxville to Medford flight tickets
United Airlines
Apr 21
TYS4:30 pmKnoxville McGhee Tyson
8h 07m
1 stop
MFR9:37 pmMedford
Apr 28
MFR5:00 amMedford
7h 06m
1 stop
TYS3:06 pmKnoxville McGhee Tyson
$377
United Airlines
Apr 21
TYS4:30 pmKnoxville McGhee Tyson
8h 07m
1 stop
MFR9:37 pmMedford
Apr 28
MFR6:31 pmMedford
13h 19m
2 stops
TYS10:50 amKnoxville McGhee Tyson
$382
United Airlines
Apr 21
TYS2:25 pmKnoxville McGhee Tyson
11h 49m
2 stops
MFR11:14 pmMedford
Apr 28
MFR6:31 pmMedford
12h 37m
2 stops
TYS10:08 amKnoxville McGhee Tyson
$387

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Medford that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 20, 2026.
Use the filters below to find and compare flights from Knoxville to Medford that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Tue 4/21

4:30 pm-9:37 pm

1 stop8h 07m

Medford

Tue 4/28

5:00 am-3:06 pm

1 stop7h 06m

$377

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Tue 4/21

4:30 pm-9:37 pm

1 stop8h 07m

Medford

Tue 4/28

6:31 pm-10:50 am

2 stops13h 19m

$382

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Tue 4/21

2:25 pm-11:14 pm

2 stops11h 49m

Medford

Tue 4/28

6:31 pm-10:08 am

2 stops12h 37m

$387

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Wed 5/6

4:20 pm-9:31 pm

1 stop8h 11m

Medford

Sat 5/30

5:00 am-4:51 pm

2 stops8h 51m

$458

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Wed 8/12

6:15 pm-11:41 pm

2 stops8h 26m

Medford

Thu 8/20

5:21 pm-10:10 am

2 stops13h 49m

$463
Quickest round-trip

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Wed 8/12

4:56 pm-9:16 pm

1 stop7h 20m

Medford

Thu 8/20

1:08 pm-10:38 pm

1 stop6h 30m

$473

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Fri 5/1

11:02 am-11:20 pm

2 stops15h 18m

Medford

Fri 5/8

5:25 pm-11:09 am

2 stops14h 44m

$478

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Wed 8/12

6:15 pm-11:41 pm

2 stops8h 26m

Medford

Thu 8/20

5:21 pm-10:10 am

2 stops13h 49m

$482

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Wed 8/12

4:56 pm-9:16 pm

1 stop7h 20m

Medford

Thu 8/20

1:08 pm-10:38 pm

1 stop6h 30m

$483

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Fri 5/1

5:54 pm-11:52 pm

2 stops8h 58m

Medford

Fri 5/8

5:25 pm-9:34 am

2 stops13h 09m

$488

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
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See travel insights to Medford from

How to get the cheapest flight ticket from Knoxville to Medford

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Knoxville to Medford flights?

You could potentially save up to 15% on your flight if you consider stops on a Knoxville to Medford flight.

When to book flights from Knoxville to Medford

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Medford according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Medford (TYS to MFR) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Medford

Fastest flight time

8h 26m

Direct flights

None
The fastest flight from Knoxville to Medford takes 8h 26m
There are no direct flights from Knoxville to Medford. There are no popular flight routes from Knoxville to Medford.
Search flight deals

  • How far is Knoxville McGhee Tyson to Medford by plane?

    Medford is 2112.6 mi away from Knoxville McGhee Tyson. In terms of flight time, this usually takes a little over 8h 26m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Medford Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Medford Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Medford Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Medford Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Medford Airport.

  • What documentation or ID do you need to fly to Medford Airport?

    The travel and health documents you'll need for your trip to Medford Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Medford Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Knoxville to Medford?

Best airlines flying from Knoxville to Medford

Compare and see reviews for airlines that fly from Knoxville to Medford with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $323Free CancellationRating
7.4
9,452 reviews
Search United Airlines flights

Traveling to a place near Medford?

Book flights to Medford if you plan to visit one of these locations
Grants Pass
Ashland
Yreka
Canyonville

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Medford?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to Medford. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Knoxville to Medford with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Knoxville to Medford flights to just show those with flexible booking policies.

How can momondo help me find flights from Knoxville to Medford?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Knoxville to Medford.

I’m not ready to book a flight from Knoxville to Medford right now. Can momondo alert me if prices change?

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