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Cheap flights from Knoxville to Medford from $319

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Medford departing on 9/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Knoxville to Medford

Cheap round-trip flights

Delta Logo
5:45 am - 12:00 pmTYS-MFR
9h 15m2 stops
Delta Logo
5:24 pm - 9:00 amMFR-TYS
12h 36m2 stops
$319Delta
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Tue, Sep 30 - Tue, Oct 7
American Airlines Logo
11:18 am - 7:16 pmTYS-MFR
10h 58m2 stops
American Airlines Logo
5:30 am - 6:50 pmMFR-TYS
10h 20m2 stops
$387American Airlines
Find Deal
Wed, Sep 17 - Wed, Sep 24
United Airlines Logo
4:40 pm - 9:04 pmTYS-MFR
7h 24m1 stop
United Airlines Logo
5:00 am - 3:10 pmMFR-TYS
7h 10m1 stop
$409United Airlines
Find Deal
Wed, Sep 17 - Wed, Sep 24
United Airlines Logo
2:30 pm - 10:19 pmTYS-MFR
10h 49m2 stops
United Airlines Logo
5:00 am - 2:50 pmMFR-TYS
6h 50m1 stop
$412United Airlines
Find Deal
Wed, Sep 10 - Sun, Sep 14
United Airlines Logo
7:00 am - 5:51 pmTYS-MFR
13h 51m2 stops
United Airlines Logo
5:00 am - 3:10 pmMFR-TYS
7h 10m1 stop
$414United Airlines
Find Deal
Wed, Sep 17 - Wed, Sep 24
United Airlines Logo
7:00 am - 10:19 pmTYS-MFR
18h 19m3 stops
United Airlines Logo
6:35 pm - 11:21 amMFR-TYS
13h 46m2 stops
$424United Airlines
Find Deal
Wed, Sep 17 - Wed, Sep 24
United Airlines Logo
7:00 am - 10:19 pmTYS-MFR
18h 19m3 stops
United Airlines Logo
5:00 am - 2:50 pmMFR-TYS
6h 50m1 stop
$479United Airlines
Find Deal
Wed, Sep 10 - Sun, Sep 14
United Airlines Logo
12:00 pm - 8:29 pmTYS-MFR
11h 29m2 stops
United Airlines Logo
6:37 pm - 10:29 amMFR-TYS
12h 52m2 stops
$546United Airlines
Find Deal
Sat, Oct 4 - Sun, Oct 12
United Airlines Logo
10:51 am - 8:29 pmTYS-MFR
12h 38m2 stops
United Airlines Logo
2:13 pm - 10:10 amMFR-TYS
16h 57m3 stops
$552United Airlines
Find Deal
Tue, Sep 30 - Tue, Oct 7
Logo
4:26 pm - 3:16 pmTYS-MFR
25h 50m3 stops
Logo
9:42 pm - 4:36 pmMFR-TYS
15h 54m3 stops
$834
Find Deal
Sat, Oct 4 - Sun, Oct 12

Delta flights from Knoxville to Medford

Our best Delta deals on Knoxville to Medford flight tickets
Delta
Sep 30
TYS5:45 amKnoxville McGhee Tyson
9h 15m
2 stops
MFR12:00 pmMedford
Oct 7
MFR5:24 pmMedford
12h 36m
2 stops
TYS9:00 amKnoxville McGhee Tyson
$319
Find similar
Delta
Oct 4
TYS11:32 amKnoxville McGhee Tyson
12h 56m
2 stops
MFR9:28 pmMedford
Oct 11
MFR5:24 pmMedford
12h 56m
2 stops
TYS9:20 amKnoxville McGhee Tyson
$967
Find similar

United Airlines flights from Knoxville to Medford

Our best United Airlines deals on Knoxville to Medford flight tickets
United Airlines
Sep 17
TYS4:40 pmKnoxville McGhee Tyson
7h 24m
1 stop
MFR9:04 pmMedford
Sep 24
MFR5:00 amMedford
7h 10m
1 stop
TYS3:10 pmKnoxville McGhee Tyson
$409
Find similar
United Airlines
Sep 10
TYS2:30 pmKnoxville McGhee Tyson
10h 49m
2 stops
MFR10:19 pmMedford
Sep 14
MFR5:00 amMedford
6h 50m
1 stop
TYS2:50 pmKnoxville McGhee Tyson
$412
Find similar
United Airlines
Sep 17
TYS7:00 amKnoxville McGhee Tyson
13h 51m
2 stops
MFR5:51 pmMedford
Sep 24
MFR5:00 amMedford
7h 10m
1 stop
TYS3:10 pmKnoxville McGhee Tyson
$414
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Medford that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 27, 2025.
Use the filters below to find and compare flights from Knoxville to Medford that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Tue 9/30

5:45 am-12:00 pm

2 stops9h 15m

Medford

Tue 10/7

5:24 pm-9:00 am

2 stops12h 36m

$319

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Wed 9/17

11:18 am-7:16 pm

2 stops10h 58m

Medford

Wed 9/24

5:30 am-6:50 pm

2 stops10h 20m

$387

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Wed 9/17

4:40 pm-9:04 pm

1 stop7h 24m

Medford

Wed 9/24

5:00 am-3:10 pm

1 stop7h 10m

$409

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Wed 9/10

2:30 pm-10:19 pm

2 stops10h 49m

Medford

Sun 9/14

5:00 am-2:50 pm

1 stop6h 50m

$412

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Wed 9/17

7:00 am-5:51 pm

2 stops13h 51m

Medford

Wed 9/24

5:00 am-3:10 pm

1 stop7h 10m

$414

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Wed 9/17

7:00 am-10:19 pm

3 stops18h 19m

Medford

Wed 9/24

6:35 pm-11:21 am

2 stops13h 46m

$424

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Wed 9/10

7:00 am-10:19 pm

3 stops18h 19m

Medford

Sun 9/14

5:00 am-2:50 pm

1 stop6h 50m

$479

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Sat 10/4

12:00 pm-8:29 pm

2 stops11h 29m

Medford

Sun 10/12

6:37 pm-10:29 am

2 stops12h 52m

$546

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Tue 9/30

10:51 am-8:29 pm

2 stops12h 38m

Medford

Tue 10/7

2:13 pm-10:10 am

3 stops16h 57m

$552

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Sat 10/4

4:26 pm-3:16 pm

3 stops25h 50m

Medford

Sun 10/12

9:42 pm-4:36 pm

3 stops15h 54m

$834

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Medford from

How to get the cheapest flight ticket from Knoxville to Medford

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Medford?

The month of March is, on average, the cheapest month to fly to Medford from Knoxville, with most prices found around $462. If you don’t want to visit Medford in March, then you should wait until January to fly from Knoxville, when ticket prices are also cheap, with an average price of $463.

What is the cheapest day to depart on your flight to Medford?

The cheapest day to depart from Knoxville to Medford is on a Tuesday when prices can be found for as low as $482. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $920. These prices are subject to change though, so be sure to set up a Price Alert for flights to Medford.

What is the cheapest time of day to depart on your flight to Medford?

In the afternoon is the cheapest time of day to fly from Knoxville to Medford when you can find flight prices for as low as $513. Flying to Medford in the afternoon is an ideal time because this is during off-peak travel hours. Flights in the morning are often more expensive with an average ticket price of $788.

Can stopping save me money on Knoxville to Medford flights?

You could potentially save up to 45% on your flight if you consider stops on a Knoxville to Medford flight.

When to book flights from Knoxville to Medford

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Medford according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Medford (TYS to MFR) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Medford

Direct flights

None
There are no direct flights from Knoxville to Medford. There are no popular flight routes from Knoxville to Medford.
Search flight deals

  • How far is Knoxville McGhee Tyson to Medford by plane?

    Medford is 2112.6 mi away from Knoxville McGhee Tyson. In terms of flight time, this usually takes a little over 7h 24m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Medford Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Medford Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Medford Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Medford Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Medford Airport.

  • What documentation or ID do you need to fly to Medford Airport?

    The travel and health documents you'll need for your trip to Medford Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Medford Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Knoxville to Medford?

Best airlines flying from Knoxville to Medford

Compare and see reviews for airlines that fly from Knoxville to Medford with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $453Free CancellationRating
7.4
8,945 reviews
Search United Airlines flights

Traveling to a place near Medford?

Book flights to Medford if you plan to visit one of these locations
Grants Pass
Ashland
Yreka
Canyonville

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Medford?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to Medford. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Knoxville to Medford with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Knoxville to Medford flights to just show those with flexible booking policies.

How can momondo help me find flights from Knoxville to Medford?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Knoxville to Medford.

I’m not ready to book a flight from Knoxville to Medford right now. Can momondo alert me if prices change?

Price alerts on flights to Medford from Knoxville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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