Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Knoxville to Los Angeles from $121

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Los Angeles departing on 10/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
12:57 pm - 12:29 amTYS  Knoxville McGhee Tyson-LAX Los Angeles
38h 32m2 stops Philadelphia Denver Intl
Multiple Airlines Logo
2:39 pm - 2:11 pmLAX  Los Angeles-TYS Knoxville McGhee Tyson
20h 32m1 stop Denver Intl
$223Multiple Airlines
Fri, Oct 23 - Sat, Oct 31
Multiple Airlines Logo
1:04 pm - 10:51 pmTYS  Knoxville McGhee Tyson-LAX Los Angeles
12h 47m1 stop Chicago Midway
Multiple Airlines Logo
2:39 pm - 2:11 pmLAX  Los Angeles-TYS Knoxville McGhee Tyson
20h 32m1 stop Denver Intl
$228Multiple Airlines
Fri, Oct 23 - Sat, Oct 31
American Airlines Logo
6:06 pm - 10:36 pmTYS  Knoxville McGhee Tyson-LAX Los Angeles
7h 30m1 stop Charlotte Douglas
American Airlines Logo
11:40 am - 11:18 pmLAX  Los Angeles-TYS Knoxville McGhee Tyson
8h 38m1 stop Dallas/Fort Worth
$277American Airlines
Wed, Oct 7 - Wed, Oct 21
American Airlines Logo
6:06 pm - 10:36 pmTYS  Knoxville McGhee Tyson-LAX Los Angeles
7h 30m1 stop Charlotte Douglas
American Airlines Logo
11:40 am - 11:18 pmLAX  Los Angeles-TYS Knoxville McGhee Tyson
8h 38m1 stop Dallas/Fort Worth
$277American Airlines
Wed, Oct 7 - Wed, Oct 21
United Airlines Logo
10:51 am - 4:40 pmTYS  Knoxville McGhee Tyson-LAX Los Angeles
8h 49m1 stop Chicago O'Hare Intl
United Airlines Logo
10:42 pm - 11:50 amLAX  Los Angeles-TYS Knoxville McGhee Tyson
10h 08m1 stop Washington, D.C. Dulles Intl
$277United Airlines
Sat, Oct 31 - Sat, Oct 31
Delta Logo
6:20 pm - 11:52 pmTYS  Knoxville McGhee Tyson-LAX Los Angeles
8h 32m1 stop Minneapolis St Paul
Delta Logo
9:45 pm - 9:29 amLAX  Los Angeles-TYS Knoxville McGhee Tyson
8h 44m1 stop Atlanta Hartsfield-Jackson
$288Delta
Wed, Sep 9 - Tue, Sep 15
Delta Logo
6:30 am - 1:15 pmTYS  Knoxville McGhee Tyson-LAX Los Angeles
9h 45m1 stop Minneapolis St Paul
Delta Logo
9:45 pm - 9:29 amLAX  Los Angeles-TYS Knoxville McGhee Tyson
8h 44m1 stop Atlanta Hartsfield-Jackson
$288Delta
Thu, Sep 10 - Tue, Sep 15
United Airlines Logo
4:53 pm - 9:17 pmTYS  Knoxville McGhee Tyson-LAX Los Angeles
7h 24m1 stop Denver Intl
United Airlines Logo
11:17 pm - 9:53 amLAX  Los Angeles-TYS Knoxville McGhee Tyson
7h 36m1 stop Chicago O'Hare Intl
$317United Airlines
Sat, Oct 24 - Thu, Oct 29
Southwest Logo
4:20 pm - 8:00 pmTYS  Knoxville McGhee Tyson-LAX Los Angeles
6h 40m1 stop Dallas Love Field
Southwest Logo
5:05 am - 7:35 pmLAX  Los Angeles-TYS Knoxville McGhee Tyson
11h 30m1 stop Baltimore/Washington
$319Southwest
Sat, Oct 3 - Sat, Oct 17
Southwest Logo
4:55 pm - 8:10 pmTYS  Knoxville McGhee Tyson-LAX Los Angeles
6h 15m1 stop Nashville Intl
Southwest Logo
5:05 am - 8:00 pmLAX  Los Angeles-TYS Knoxville McGhee Tyson
11h 55m1 stop Baltimore/Washington
$322Southwest
Sat, Sep 5 - Fri, Sep 11

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

American Airlines flights from Knoxville to Los Angeles

Our best American Airlines deals on Knoxville to Los Angeles flight tickets
American Airlines
Oct 7
TYS6:06 pmKnoxville McGhee Tyson
7h 30m
1 stop
LAX10:36 pmLos Angeles
Oct 21
LAX11:40 amLos Angeles
8h 38m
1 stop
TYS11:18 pmKnoxville McGhee Tyson
$277
American Airlines
Dec 15
TYS2:55 pmKnoxville McGhee Tyson
7h 10m
1 stop
LAX7:05 pmLos Angeles
Jan 8
LAX11:45 pmLos Angeles
8h 23m
1 stop
TYS11:08 amKnoxville McGhee Tyson
$305
American Airlines
Sep 9
TYS7:30 amKnoxville McGhee Tyson
9h 33m
1 stop
LAX2:03 pmLos Angeles
Sep 11
LAX12:30 amLos Angeles
7h 47m
1 stop
TYS11:17 amKnoxville McGhee Tyson
$306

Southwest flights from Knoxville to Los Angeles

Our best Southwest deals on Knoxville to Los Angeles flight tickets
Southwest
Oct 3
TYS4:20 pmKnoxville McGhee Tyson
6h 40m
1 stop
LAX8:00 pmLos Angeles
Oct 17
LAX5:05 amLos Angeles
11h 30m
1 stop
TYS7:35 pmKnoxville McGhee Tyson
$319
Southwest
Sep 5
TYS4:55 pmKnoxville McGhee Tyson
6h 15m
1 stop
LAX8:10 pmLos Angeles
Sep 11
LAX5:05 amLos Angeles
11h 55m
1 stop
TYS8:00 pmKnoxville McGhee Tyson
$322
Southwest
Oct 3
TYS2:55 pmKnoxville McGhee Tyson
8h 05m
2 stops
LAX8:00 pmLos Angeles
Oct 17
LAX5:05 amLos Angeles
11h 30m
1 stop
TYS7:35 pmKnoxville McGhee Tyson
$325

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Los Angeles that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 16, 2026.
Use the filters below to find and compare flights from Knoxville to Los Angeles that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleLos Angeles

TYS Knoxville McGhee Tyson - LAX Los Angeles

TYSLAX

Knoxville McGhee Tyson

Fri 10/23

12:57 pm-12:29 am

2 stops38h 32m

Los Angeles

Sat 10/31

2:39 pm-2:11 pm

1 stop20h 32m

$223

KnoxvilleLos Angeles

TYS Knoxville McGhee Tyson - LAX Los Angeles

TYSLAX

Knoxville McGhee Tyson

Fri 10/23

1:04 pm-10:51 pm

1 stop12h 47m

Los Angeles

Sat 10/31

2:39 pm-2:11 pm

1 stop20h 32m

$228

KnoxvilleLos Angeles

TYS Knoxville McGhee Tyson - LAX Los Angeles

TYSLAX

Knoxville McGhee Tyson

Wed 10/7

6:06 pm-10:36 pm

1 stop7h 30m

Los Angeles

Wed 10/21

11:40 am-11:18 pm

1 stop8h 38m

$277

KnoxvilleLos Angeles

TYS Knoxville McGhee Tyson - LAX Los Angeles

TYSLAX

Knoxville McGhee Tyson

Wed 10/7

6:06 pm-10:36 pm

1 stop7h 30m

Los Angeles

Wed 10/21

11:40 am-11:18 pm

1 stop8h 38m

$277

KnoxvilleLos Angeles

TYS Knoxville McGhee Tyson - LAX Los Angeles

TYSLAX

Knoxville McGhee Tyson

Sat 10/31

10:51 am-4:40 pm

1 stop8h 49m

Los Angeles

Sat 10/31

10:42 pm-11:50 am

1 stop10h 08m

$277

KnoxvilleLos Angeles

TYS Knoxville McGhee Tyson - LAX Los Angeles

TYSLAX

Knoxville McGhee Tyson

Wed 9/9

6:20 pm-11:52 pm

1 stop8h 32m

Los Angeles

Tue 9/15

9:45 pm-9:29 am

1 stop8h 44m

$288

KnoxvilleLos Angeles

TYS Knoxville McGhee Tyson - LAX Los Angeles

TYSLAX

Knoxville McGhee Tyson

Thu 9/10

6:30 am-1:15 pm

1 stop9h 45m

Los Angeles

Tue 9/15

9:45 pm-9:29 am

1 stop8h 44m

$288
Quickest round-trip

KnoxvilleLos Angeles

TYS Knoxville McGhee Tyson - LAX Los Angeles

TYSLAX

Knoxville McGhee Tyson

Sat 10/24

4:53 pm-9:17 pm

1 stop7h 24m

Los Angeles

Thu 10/29

11:17 pm-9:53 am

1 stop7h 36m

$317

KnoxvilleLos Angeles

TYS Knoxville McGhee Tyson - LAX Los Angeles

TYSLAX

Knoxville McGhee Tyson

Sat 10/3

4:20 pm-8:00 pm

1 stop6h 40m

Los Angeles

Sat 10/17

5:05 am-7:35 pm

1 stop11h 30m

$319

KnoxvilleLos Angeles

TYS Knoxville McGhee Tyson - LAX Los Angeles

TYSLAX

Knoxville McGhee Tyson

Sat 9/5

4:55 pm-8:10 pm

1 stop6h 15m

Los Angeles

Fri 9/11

5:05 am-8:00 pm

1 stop11h 55m

$322

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Los Angeles from

How to get the cheapest flight ticket from Knoxville to Los Angeles

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Knoxville and Los Angeles?

Prices are currently low for flights on this route.

Typical prices usually range from $323 to $448.
The lowest price recently found on this route was $223.

What is the cheapest month to fly to Los Angeles?

The month of February is, on average, the cheapest month to fly to Los Angeles from Knoxville, with most prices found around $367. If you aren’t able to travel during the month of February, then book flights to Los Angeles from Knoxville during August instead. Flights to Los Angeles in August, while not as cheap as those in February, still average around $396.

How far in advance should I book a flight from Knoxville to Los Angeles?

You are more likely to see cheaper flights to Los Angeles from Knoxville when booking weeks ahead of your departure date. In general, you can expect to find flights to Los Angeles for around $439 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Los Angeles from Knoxville for as low as $370 on momondo.

How have Knoxville to Los Angeles flight prices changed over time?

As of August 2026, prices for Knoxville to Los Angeles flights are approximately 67% more expensive when compared to flights at the same time last year.

When to book flights from Knoxville to Los Angeles

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Los Angeles according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Los Angeles (TYS to LAX) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Los Angeles

Fastest flight time

6h 15m

Direct flights

None
The fastest flight from Knoxville to Los Angeles takes 6h 15m
There are no direct flights from Knoxville to Los Angeles. There are no popular flight routes from Knoxville to Los Angeles.
Search flight deals

Frequently asked questions about flying from Knoxville to Los Angeles

  • How far is Knoxville McGhee Tyson to Los Angeles by plane?

    Knoxville McGhee Tyson and Los Angeles are 1939.6 mi apart from one another. 6h 15m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Los Angeles Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Los Angeles Airport are updated daily.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Los Angeles Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Los Angeles Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Los Angeles Airport.

  • What documentation or ID do you need to fly to Los Angeles Airport?

    The required travel and health documents for your Los Angeles Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Los Angeles Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Knoxville to Los Angeles?

Best airlines flying from Knoxville to Los Angeles

Compare and see reviews for airlines that fly from Knoxville to Los Angeles with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $142Free CancellationRating
5.6
2,686 reviews
Search Frontier flights
DeltaPriceFrom $276Free CancellationRating
7.8
8,505 reviews
Search Delta flights
American AirlinesPriceFrom $288Free CancellationRating
7.1
11,947 reviews
Search American Airlines flights
United AirlinesPriceFrom $298Free CancellationRating
7.4
10,106 reviews
Search United Airlines flights
SouthwestPriceFrom $354Free CancellationRating
8.0
4,218 reviews
Search Southwest flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Avalon
Laguna Beach
Big Bear Lake
Carlsbad
Temecula
Riverside
Oceanside
Inglewood
Big Bear
San Clemente
Newport Beach
Pasadena
Malibu
Orange
Ventura
Huntington Beach
Buena Park
West Hollywood
Irvine
Downey

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Los Angeles?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to Los Angeles. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Knoxville to Los Angeles with flexible booking policies on momondo?

Yes. All flights to Los Angeles from Knoxville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Knoxville to Los Angeles?

Once all potential Knoxville to Los Angeles flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Knoxville to Los Angeles right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Knoxville to Los Angeles now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Los Angeles and let you know when they change.

An easier way to manage your Los Angeles trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Tue 9/15
Tue 9/22
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States