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Cheap flights from Iowa to San Diego from $96

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Iowa to San Diego departing on 12/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Iowa to San Diego

Cheap round-trip flights

Logo
7:30 am - 6:42 pmDSM-SAN
13h 12m1 stop
Logo
6:15 am - 2:27 pmSAN-DSM
6h 12m1 stop
$170
Find Deal
Wed, Oct 8 - Wed, Oct 15
Logo
1:20 pm - 6:42 pmOMA-SAN
7h 22m1 stop
Logo
7:47 pm - 10:55 amSAN-OMA
13h 08m1 stop
$181
Find Deal
Mon, Oct 6 - Thu, Oct 9
Frontier Logo
2:25 pm - 8:07 pmDSM-SAN
7h 42m1 stop
Frontier Logo
6:35 am - 1:40 pmSAN-DSM
5h 05m1 stop
$200Frontier
Find Deal
Thu, Sep 4 - Mon, Sep 8
Frontier Logo
7:48 pm - 11:53 pmOMA-SAN
6h 05m1 stop
Frontier Logo
6:35 am - 1:21 pmSAN-OMA
4h 46m1 stop
$205Frontier
Find Deal
Thu, Oct 2 - Mon, Oct 6
American Airlines Logo
2:22 pm - 7:24 pmOMA-SAN
7h 02m1 stop
American Airlines Logo
6:15 am - 3:15 pmSAN-OMA
7h 00m1 stop
$233American Airlines
Find Deal
Tue, Sep 9 - Sat, Sep 13
Southwest Logo
3:00 pm - 9:50 pmOMA-SAN
8h 50m2 stops
Southwest Logo
2:05 pm - 10:45 pmSAN-OMA
6h 40m1 stop
$238Southwest
Find Deal
Mon, Sep 8 - Tue, Sep 9
American Airlines Logo
12:04 pm - 7:27 pmOMA-SAN
9h 23m1 stop
American Airlines Logo
1:41 pm - 10:59 pmSAN-OMA
7h 18m1 stop
$245American Airlines
Find Deal
Sat, Oct 4 - Tue, Oct 7
Delta Logo
7:04 am - 12:35 pmOMA-SAN
7h 31m1 stop
Delta Logo
12:50 pm - 11:56 pmSAN-OMA
9h 06m1 stop
$257Delta
Find Deal
Sat, Nov 8 - Sat, Nov 15
Southwest Logo
11:20 am - 9:50 pmOMA-SAN
12h 30m2 stops
Southwest Logo
5:05 pm - 11:55 pmSAN-OMA
4h 50m1 stop
$265Southwest
Find Deal
Tue, Sep 30 - Fri, Oct 3
Delta Logo
7:00 am - 10:57 amDSM-SAN
5h 57m1 stop
Delta Logo
10:30 pm - 10:30 amSAN-DSM
10h 00m1 stop
$272Delta
Find Deal
Thu, Sep 25 - Tue, Sep 30

Delta flights from Iowa to San Diego

Our best Delta deals on Iowa to San Diego flight tickets
Delta
Nov 8
OMA7:04 amOmaha Eppley Airfield
7h 31m
1 stop
SAN12:35 pmSan Diego
Nov 15
SAN12:50 pmSan Diego
9h 06m
1 stop
OMA11:56 pmOmaha Eppley Airfield
$257
Find similar
Delta
Sep 25
DSM7:00 amDes Moines
5h 57m
1 stop
SAN10:57 amSan Diego
Sep 30
SAN10:30 pmSan Diego
10h 00m
1 stop
DSM10:30 amDes Moines
$272
Find similar
Delta
Jan 14
CID7:00 amCedar Rapids
8h 07m
1 stop
SAN1:07 pmSan Diego
Jan 20
SAN12:05 pmSan Diego
8h 31m
1 stop
CID10:36 pmCedar Rapids
$277
Find similar

Frontier flights from Iowa to San Diego

Our best Frontier deals on Iowa to San Diego flight tickets
Frontier
Sep 4
DSM2:25 pmDes Moines
7h 42m
1 stop
SAN8:07 pmSan Diego
Sep 8
SAN6:35 amSan Diego
5h 05m
1 stop
DSM1:40 pmDes Moines
$200
Find similar
Frontier
Aug 16
OMA7:51 pmOmaha Eppley Airfield
5h 11m
1 stop
SAN11:02 pmSan Diego
Aug 23
SAN6:25 amSan Diego
5h 53m
1 stop
OMA2:18 pmOmaha Eppley Airfield
$203
Find similar
Frontier
Oct 2
OMA7:48 pmOmaha Eppley Airfield
6h 05m
1 stop
SAN11:53 pmSan Diego
Oct 6
SAN6:35 amSan Diego
4h 46m
1 stop
OMA1:21 pmOmaha Eppley Airfield
$205
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Iowa to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 11, 2025.
Use the filters below to find and compare flights from Iowa to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSan Diego

DSM - SAN

DSMSAN

Des Moines

Wed 10/8

7:30 am-6:42 pm

1 stop13h 12m

San Diego

Wed 10/15

6:15 am-2:27 pm

1 stop6h 12m

$170

OmahaSan Diego

OMA - SAN

OMASAN

Omaha Eppley Airfield

Mon 10/6

1:20 pm-6:42 pm

1 stop7h 22m

San Diego

Thu 10/9

7:47 pm-10:55 am

1 stop13h 08m

$181

Des MoinesSan Diego

DSM - SAN

DSMSAN

Des Moines

Thu 9/4

2:25 pm-8:07 pm

1 stop7h 42m

San Diego

Mon 9/8

6:35 am-1:40 pm

1 stop5h 05m

$200

OmahaSan Diego

OMA - SAN

OMASAN

Omaha Eppley Airfield

Thu 10/2

7:48 pm-11:53 pm

1 stop6h 05m

San Diego

Mon 10/6

6:35 am-1:21 pm

1 stop4h 46m

$205

OmahaSan Diego

OMA - SAN

OMASAN

Omaha Eppley Airfield

Tue 9/9

2:22 pm-7:24 pm

1 stop7h 02m

San Diego

Sat 9/13

6:15 am-3:15 pm

1 stop7h 00m

$233

OmahaSan Diego

OMA - SAN

OMASAN

Omaha Eppley Airfield

Mon 9/8

3:00 pm-9:50 pm

2 stops8h 50m

San Diego

Tue 9/9

2:05 pm-10:45 pm

1 stop6h 40m

$238

OmahaSan Diego

OMA - SAN

OMASAN

Omaha Eppley Airfield

Sat 10/4

12:04 pm-7:27 pm

1 stop9h 23m

San Diego

Tue 10/7

1:41 pm-10:59 pm

1 stop7h 18m

$245

OmahaSan Diego

OMA - SAN

OMASAN

Omaha Eppley Airfield

Sat 11/8

7:04 am-12:35 pm

1 stop7h 31m

San Diego

Sat 11/15

12:50 pm-11:56 pm

1 stop9h 06m

$257

OmahaSan Diego

OMA - SAN

OMASAN

Omaha Eppley Airfield

Tue 9/30

11:20 am-9:50 pm

2 stops12h 30m

San Diego

Fri 10/3

5:05 pm-11:55 pm

1 stop4h 50m

$265

Des MoinesSan Diego

DSM - SAN

DSMSAN

Des Moines

Thu 9/25

7:00 am-10:57 am

1 stop5h 57m

San Diego

Tue 9/30

10:30 pm-10:30 am

1 stop10h 00m

$272

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Iowa to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of June, then departing from Iowa during the month July is also very affordable. Most momondo users find prices during this month for around $292.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Iowa to San Diego is on a Monday. Travelers who choose to depart for San Diego on a Monday will often find tickets for as low as $166. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $468. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is at noon when flights can be purchased for as low as $170. Flights in the morning are often more expensive with an average ticket price of $433.

What is the cheapest Iowa to San Diego flight route?

Fly from Des Moines to San Diego for the best Iowa - San Diego flight prices

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Iowa when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $383 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Iowa for as low as $273 on momondo.

What cabin class options are available on Iowa to San Diego flights?

There are 1 cabin classes available to choose from on Iowa to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Iowa to San Diego flights?

You could potentially save up to 25% on your flight if you consider stops on a Iowa to San Diego flight.

Cheap Iowa to San Diego flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to San Diego

Best Price Found

$96

Fastest flight time

4h 51m

Direct flights

Mon, Wed, Thu, Sat and Sun

Airports in San Diego

1 airport
The best one-way flight to San Diego from Iowa in the past 72 hours is $96. The best round-trip flight deal from Iowa to San Diego found on momondo in the last 72 hours is $170.
The fastest flight from Iowa to San Diego takes 4h 51m
Direct flights go from Iowa to San Diego on Monday, Wednesday, Thursday, Saturday and Sunday. The only airline offering direct flights is Southwest.
There is 1 airport near San Diego: San Diego (SAN)
Search flight deals

  • When did momondo last update prices for flights from Iowa to San Diego Airport?

    Prices for flights from Iowa to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Iowa to San Diego Airport?

  • How old do you have to be to fly from Iowa to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Iowa to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Iowa to San Diego?

Best airlines flying from Iowa to San Diego

Compare and see reviews for airlines that fly from Iowa to San Diego with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $110Free CancellationRating
5.8
3,221 reviews
Search Frontier flights
Allegiant AirPriceFrom $111Free CancellationRating
7.2
702 reviews
Search Allegiant Air flights
American AirlinesPriceFrom $244Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $263Free CancellationRating
7.4
8,920 reviews
Search United Airlines flights
DeltaPriceFrom $276Free CancellationRating
8.0
7,979 reviews
Search Delta flights
SouthwestPriceFrom $356Free CancellationRating
8.0
4,248 reviews
Search Southwest flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
La Mesa
Imperial Beach
Poway
San Ysidro
Borrego Springs
Alpine
Lemon Grove
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to San Diego?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Iowa to San Diego for you.

Can I find flights from Iowa to San Diego with flexible booking policies on momondo?

Yes. All flights to San Diego from Iowa on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Iowa to San Diego?

momondo provides multiple filters to help you find the best flight to San Diego from Iowa. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Iowa to San Diego right now. Can momondo alert me if prices change?

If you are simply researching potential flights to San Diego, momondo offers a useful price alert feature which will track prices for flights to San Diego from Iowa and alert you when they change.

An easier way to manage your San Diego trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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