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Cheap flights from Iowa to San Diego from $60

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Iowa to San Diego departing on 4/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Iowa to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
8:21 pm - 9:14 pm
DSM
-
SAN
26h 53m
1 stop
Frontier Logo
6:25 am - 7:14 pm
SAN
-
DSM
10h 49m
1 stop
$184Frontier
Mon, Mar 30 - Fri, Apr 10
Frontier Logo
2:46 pm - 12:02 am
CID
-
SAN
11h 16m
1 stop
Frontier Logo
6:25 am - 1:51 pm
SAN
-
CID
5h 26m
1 stop
$190Frontier
Mon, Apr 13 - Fri, Apr 17
Frontier Logo
8:14 pm - 12:02 am
DSM
-
SAN
5h 48m
1 stop
Frontier Logo
9:28 pm - 7:14 pm
SAN
-
DSM
19h 46m
1 stop
$197Frontier
Fri, Apr 10 - Sun, Apr 12
Multiple Airlines Logo
3:02 pm - 1:13 pm
DSM
-
SAN
24h 11m
1 stop
Multiple Airlines Logo
9:28 pm - 7:14 pm
SAN
-
DSM
19h 46m
1 stop
$205Multiple Airlines
Mon, Mar 30 - Sun, Apr 5
Delta Logo
2:00 pm - 9:44 pm
OMA
-
SAN
9h 44m
1 stop
Delta Logo
12:50 pm - 11:55 pm
SAN
-
OMA
9h 05m
1 stop
$217Delta
Thu, Jul 2 - Tue, Jul 7
Multiple Airlines Logo
3:02 pm - 1:13 pm
DSM
-
SAN
24h 11m
1 stop
Multiple Airlines Logo
8:06 am - 7:14 pm
SAN
-
DSM
33h 08m
2 stops
$219Multiple Airlines
Mon, Mar 30 - Thu, Apr 2
United Airlines Logo
1:50 pm - 8:02 pm
OMA
-
SAN
8h 12m
2 stops
United Airlines Logo
4:04 pm - 11:42 pm
SAN
-
OMA
5h 38m
1 stop
$222United Airlines
Fri, May 8 - Mon, May 11
Southwest Logo
6:55 pm - 10:35 pm
OMA
-
SAN
5h 40m
1 stop
Southwest Logo
9:35 pm - 12:15 pm
SAN
-
OMA
12h 40m
2 stops
$228Southwest
Tue, Mar 31 - Tue, Apr 7
Delta Logo
5:45 pm - 11:43 pm
OMA
-
SAN
7h 58m
1 stop
Delta Logo
5:01 pm - 11:59 pm
SAN
-
OMA
4h 58m
1 stop
$229Delta
Tue, May 12 - Fri, May 15
United Airlines Logo
8:54 am - 2:57 pm
MLI
-
SAN
8h 03m
1 stop
United Airlines Logo
2:10 pm - 11:02 pm
SAN
-
MLI
6h 52m
1 stop
$251United Airlines
Wed, Apr 1 - Wed, Apr 8

Frontier flights from Iowa to San Diego

Our best Frontier deals on Iowa to San Diego flight tickets
Frontier
Mar 30
DSM8:21 pmDes Moines
26h 53m
1 stop
SAN9:14 pmSan Diego
Apr 10
SAN6:25 amSan Diego
10h 49m
1 stop
DSM7:14 pmDes Moines
$184
Frontier
Apr 13
CID2:46 pmCedar Rapids
11h 16m
1 stop
SAN12:02 amSan Diego
Apr 17
SAN6:25 amSan Diego
5h 26m
1 stop
CID1:51 pmCedar Rapids
$190
Frontier
Apr 10
DSM8:14 pmDes Moines
5h 48m
1 stop
SAN12:02 amSan Diego
Apr 12
SAN9:28 pmSan Diego
19h 46m
1 stop
DSM7:14 pmDes Moines
$197

United Airlines flights from Iowa to San Diego

Our best United Airlines deals on Iowa to San Diego flight tickets
United Airlines
May 8
OMA1:50 pmOmaha Eppley Airfield
8h 12m
2 stops
SAN8:02 pmSan Diego
May 11
SAN4:04 pmSan Diego
5h 38m
1 stop
OMA11:42 pmOmaha Eppley Airfield
$222
United Airlines
Mar 30
OMA3:01 pmOmaha Eppley Airfield
7h 04m
1 stop
SAN8:05 pmSan Diego
Apr 14
SAN12:40 pmSan Diego
5h 47m
1 stop
OMA8:27 pmOmaha Eppley Airfield
$245
United Airlines
Mar 7
OMA5:25 pmOmaha Eppley Airfield
5h 38m
1 stop
SAN9:03 pmSan Diego
Mar 31
SAN8:45 amSan Diego
5h 35m
1 stop
OMA4:20 pmOmaha Eppley Airfield
$248

momondo Fare Finder

 
Customize your flight search to find flights from Iowa to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 2, 2026.
Use the filters below to find and compare flights from Iowa to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSan Diego

DSM - SAN

DSMSAN

Des Moines

Mon 3/30

8:21 pm-9:14 pm

1 stop26h 53m

San Diego

Fri 4/10

6:25 am-7:14 pm

1 stop10h 49m

$184

Cedar RapidsSan Diego

CID - SAN

CIDSAN

Cedar Rapids

Mon 4/13

2:46 pm-12:02 am

1 stop11h 16m

San Diego

Fri 4/17

6:25 am-1:51 pm

1 stop5h 26m

$190

Des MoinesSan Diego

DSM - SAN

DSMSAN

Des Moines

Fri 4/10

8:14 pm-12:02 am

1 stop5h 48m

San Diego

Sun 4/12

9:28 pm-7:14 pm

1 stop19h 46m

$197

Des MoinesSan Diego

DSM - SAN

DSMSAN

Des Moines

Mon 3/30

3:02 pm-1:13 pm

1 stop24h 11m

San Diego

Sun 4/5

9:28 pm-7:14 pm

1 stop19h 46m

$205

OmahaSan Diego

OMA - SAN

OMASAN

Omaha Eppley Airfield

Thu 7/2

2:00 pm-9:44 pm

1 stop9h 44m

San Diego

Tue 7/7

12:50 pm-11:55 pm

1 stop9h 05m

$217

Des MoinesSan Diego

DSM - SAN

DSMSAN

Des Moines

Mon 3/30

3:02 pm-1:13 pm

1 stop24h 11m

San Diego

Thu 4/2

8:06 am-7:14 pm

2 stops33h 08m

$219

OmahaSan Diego

OMA - SAN

OMASAN

Omaha Eppley Airfield

Fri 5/8

1:50 pm-8:02 pm

2 stops8h 12m

San Diego

Mon 5/11

4:04 pm-11:42 pm

1 stop5h 38m

$222

OmahaSan Diego

OMA - SAN

OMASAN

Omaha Eppley Airfield

Tue 3/31

6:55 pm-10:35 pm

1 stop5h 40m

San Diego

Tue 4/7

9:35 pm-12:15 pm

2 stops12h 40m

$228

OmahaSan Diego

OMA - SAN

OMASAN

Omaha Eppley Airfield

Tue 5/12

5:45 pm-11:43 pm

1 stop7h 58m

San Diego

Fri 5/15

5:01 pm-11:59 pm

1 stop4h 58m

$229

MolineSan Diego

MLI - SAN

MLISAN

Moline Quad-City

Wed 4/1

8:54 am-2:57 pm

1 stop8h 03m

San Diego

Wed 4/8

2:10 pm-11:02 pm

1 stop6h 52m

$251

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Iowa to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of August, then departing from Iowa during the month July is also very affordable. Most momondo users find prices during this month for around $292.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Iowa to San Diego is on a Monday. Travelers who choose to depart for San Diego on a Monday will often find tickets for as low as $161. If your travel schedule is flexible, try to avoid departing on a Tuesday because tickets tend to average around $179. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest Iowa to San Diego flight route?

Fly from Des Moines to San Diego for the best Iowa - San Diego flight prices

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Iowa when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $370 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Iowa for as low as $261 on momondo.

What cabin class options are available on Iowa to San Diego flights?

There is only 1 cabin class available to choose from on Iowa to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Iowa to San Diego flights?

No. A direct flight is the cheapest option for a flight between Iowa to San Diego.

Cheap Iowa to San Diego flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to San Diego

Fastest flight time

3h 10m

Direct flights

Mon, Tue, Thu, Fri, Sat and Sun

Airports in San Diego

1 airport
The fastest flight from Iowa to San Diego takes 3h 10m
Direct flights go from Iowa to San Diego on Monday, Tuesday, Thursday, Friday, Saturday and Sunday. There are no airlines offering direct flights.
There is 1 airport in San Diego. From Iowa there are direct flights to San Diego (SAN).
Search flight deals

  • When did momondo last update prices for flights from Iowa to San Diego Airport?

    Prices for flights from Iowa to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Iowa to San Diego Airport?

  • How old do you have to be to fly from Iowa to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Iowa to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Iowa to San Diego?

Best airlines flying from Iowa to San Diego

Compare and see reviews for airlines that fly from Iowa to San Diego with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $100Free CancellationRating
5.7
3,039 reviews
Search Frontier flights
Allegiant AirPriceFrom $101Free CancellationRating
7.3
714 reviews
Search Allegiant Air flights
DeltaPriceFrom $118Free CancellationRating
7.9
8,237 reviews
Search Delta flights
American AirlinesPriceFrom $228Free CancellationRating
7.1
11,369 reviews
Search American Airlines flights
United AirlinesPriceFrom $253Free CancellationRating
7.4
9,375 reviews
Search United Airlines flights
SouthwestPriceFrom $303Free CancellationRating
8.0
4,307 reviews
Search Southwest flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
Poway
National City
Imperial Beach
San Ysidro
Borrego Springs
La Mesa
Alpine
Lemon Grove
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to San Diego?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Iowa to San Diego for you.

Can I find flights from Iowa to San Diego with flexible booking policies on momondo?

Yes. All flights to San Diego from Iowa on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Iowa to San Diego?

momondo provides multiple filters to help you find the best flight to San Diego from Iowa. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Iowa to San Diego right now. Can momondo alert me if prices change?

If you are simply researching potential flights to San Diego, momondo offers a useful price alert feature which will track prices for flights to San Diego from Iowa and alert you when they change.

An easier way to manage your San Diego trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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