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Cheap flights from Iowa to Sao Paulo from $349

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Iowa to Sao Paulo departing on 3/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Iowa to Sao Paulo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:56 pm - 3:50 am
DSM
-
GRU
30h 54m
2 stops
Multiple Airlines Logo
1:30 am - 6:01 pm
GRU
-
DSM
18h 31m
2 stops
$834Multiple Airlines
Sat, Mar 21 - Fri, Mar 27
Multiple Airlines Logo
6:56 pm - 3:50 am
DSM
-
GRU
30h 54m
2 stops
Multiple Airlines Logo
1:30 am - 6:01 pm
GRU
-
DSM
18h 31m
2 stops
$835Multiple Airlines
Sat, Mar 21 - Fri, Mar 27
Multiple Airlines Logo
10:20 am - 12:10 am
DSM
-
GRU
35h 50m
2 stops
Multiple Airlines Logo
10:50 pm - 10:48 am
GRU
-
DSM
13h 58m
1 stop
$980Multiple Airlines
Mon, Mar 23 - Mon, Mar 30
LATAM Airlines Logo
6:30 pm - 8:00 pm
DSM
-
GRU
23h 30m
2 stops
LATAM Airlines Logo
11:40 am - 10:14 am
GRU
-
DSM
24h 34m
2 stops
$1,059LATAM Airlines
Sun, Jun 21 - Wed, Jul 8
LATAM Airlines Logo
2:50 pm - 7:50 am
OMA
-
GRU
15h 00m
2 stops
LATAM Airlines Logo
11:45 pm - 9:15 pm
GRU
-
OMA
23h 30m
2 stops
$1,059LATAM Airlines
Mon, Jun 22 - Tue, Jul 7
Delta Logo
10:15 am - 7:50 am
DSM
-
GRU
19h 35m
2 stops
Delta Logo
7:00 pm - 5:42 pm
GRU
-
DSM
24h 42m
2 stops
$1,067Delta
Mon, Jun 22 - Mon, Jul 6
LATAM Airlines Logo
11:04 am - 5:30 am
DSM
-
GRU
16h 26m
2 stops
LATAM Airlines Logo
11:45 pm - 10:26 pm
GRU
-
DSM
24h 41m
2 stops
$1,095LATAM Airlines
Tue, Jun 23 - Fri, Jul 10
Delta Logo
7:04 am - 5:40 am
OMA
-
GRU
20h 36m
1 stop
Delta Logo
7:30 am - 12:10 am
GRU
-
OMA
18h 40m
2 stops
$1,133Delta
Wed, Apr 15 - Thu, Apr 30
Delta Logo
10:29 am - 6:45 am
OMA
-
GRU
18h 16m
2 stops
Delta Logo
7:30 am - 12:10 am
GRU
-
OMA
18h 40m
2 stops
$1,137Delta
Wed, Apr 15 - Thu, Apr 30
Multiple Airlines Logo
10:20 am - 7:50 am
DSM
-
GRU
19h 30m
1 stop
Multiple Airlines Logo
10:50 pm - 10:48 am
GRU
-
DSM
13h 58m
1 stop
$1,144Multiple Airlines
Mon, Mar 23 - Mon, Mar 30

LATAM Airlines flights from Iowa to Sao Paulo

Our best LATAM Airlines deals on Iowa to Sao Paulo flight tickets
LATAM Airlines
Jun 21
DSM6:30 pmDes Moines
23h 30m
2 stops
GRU8:00 pmSao Paulo Guarulhos Intl
Jul 8
GRU11:40 amSao Paulo Guarulhos Intl
24h 34m
2 stops
DSM10:14 amDes Moines
$1,059
LATAM Airlines
Jun 23
DSM11:04 amDes Moines
16h 26m
2 stops
GRU5:30 amSao Paulo Guarulhos Intl
Jul 10
GRU11:45 pmSao Paulo Guarulhos Intl
24h 41m
2 stops
DSM10:26 pmDes Moines
$1,095
LATAM Airlines
Jun 20
DSM6:30 pmDes Moines
23h 30m
2 stops
GRU8:00 pmSao Paulo Guarulhos Intl
Jul 7
GRU12:50 pmSao Paulo Guarulhos Intl
23h 24m
2 stops
DSM10:14 amDes Moines
$1,099

Delta flights from Iowa to Sao Paulo

Our best Delta deals on Iowa to Sao Paulo flight tickets
Delta
Jun 22
DSM10:15 amDes Moines
19h 35m
2 stops
GRU7:50 amSao Paulo Guarulhos Intl
Jul 6
GRU7:00 pmSao Paulo Guarulhos Intl
24h 42m
2 stops
DSM5:42 pmDes Moines
$1,067
Delta
Apr 15
OMA7:04 amOmaha Eppley Airfield
20h 36m
1 stop
GRU5:40 amSao Paulo Guarulhos Intl
Apr 30
GRU7:30 amSao Paulo Guarulhos Intl
18h 40m
2 stops
OMA12:10 amOmaha Eppley Airfield
$1,133
Delta
Apr 15
OMA10:29 amOmaha Eppley Airfield
18h 16m
2 stops
GRU6:45 amSao Paulo Guarulhos Intl
Apr 30
GRU7:30 amSao Paulo Guarulhos Intl
18h 40m
2 stops
OMA12:10 amOmaha Eppley Airfield
$1,137

momondo Fare Finder

 
Customize your flight search to find flights from Iowa to Sao Paulo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 7, 2026.
Use the filters below to find and compare flights from Iowa to Sao Paulo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sat 3/21

6:56 pm-3:50 am

2 stops30h 54m

Sao Paulo Guarulhos Intl

Fri 3/27

1:30 am-6:01 pm

2 stops18h 31m

$834

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sat 3/21

6:56 pm-3:50 am

2 stops30h 54m

Sao Paulo Guarulhos Intl

Fri 3/27

1:30 am-6:01 pm

2 stops18h 31m

$835

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Mon 3/23

10:20 am-12:10 am

2 stops35h 50m

Sao Paulo Guarulhos Intl

Mon 3/30

10:50 pm-10:48 am

1 stop13h 58m

$980

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sun 6/21

6:30 pm-8:00 pm

2 stops23h 30m

Sao Paulo Guarulhos Intl

Wed 7/8

11:40 am-10:14 am

2 stops24h 34m

$1,059

OmahaSao Paulo

OMA - GRU

OMAGRU

Omaha Eppley Airfield

Mon 6/22

2:50 pm-7:50 am

2 stops15h 00m

Sao Paulo Guarulhos Intl

Tue 7/7

11:45 pm-9:15 pm

2 stops23h 30m

$1,059

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Mon 6/22

10:15 am-7:50 am

2 stops19h 35m

Sao Paulo Guarulhos Intl

Mon 7/6

7:00 pm-5:42 pm

2 stops24h 42m

$1,067

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Tue 6/23

11:04 am-5:30 am

2 stops16h 26m

Sao Paulo Guarulhos Intl

Fri 7/10

11:45 pm-10:26 pm

2 stops24h 41m

$1,095

OmahaSao Paulo

OMA - GRU

OMAGRU

Omaha Eppley Airfield

Wed 4/15

7:04 am-5:40 am

1 stop20h 36m

Sao Paulo Guarulhos Intl

Thu 4/30

7:30 am-12:10 am

2 stops18h 40m

$1,133

OmahaSao Paulo

OMA - GRU

OMAGRU

Omaha Eppley Airfield

Wed 4/15

10:29 am-6:45 am

2 stops18h 16m

Sao Paulo Guarulhos Intl

Thu 4/30

7:30 am-12:10 am

2 stops18h 40m

$1,137

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Mon 3/23

10:20 am-7:50 am

1 stop19h 30m

Sao Paulo Guarulhos Intl

Mon 3/30

10:50 pm-10:48 am

1 stop13h 58m

$1,144

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Sao Paulo from

How to get the cheapest flight ticket from Iowa to Sao Paulo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Iowa to Sao Paulo?

LATAM Airlines, American Airlines, and United Airlines are the most popular carriers operating from Iowa to Sao Paulo

Cheap Iowa to Sao Paulo flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to Sao Paulo

Fastest flight time

13h 05m

Direct flights

None
The fastest flight from Iowa to Sao Paulo takes 13h 05m
There are no direct flights from Iowa to Sao Paulo. There are no popular flight routes from Iowa to Sao Paulo.
Search flight deals

  • When did momondo last update prices for flights from Iowa to Sao Paulo?

    Prices for flights from Iowa to Sao Paulo were last updated today.

  • How old do you have to be to fly from Iowa to Sao Paulo?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Iowa to Sao Paulo.

  • What documentation or ID do you need to fly to Sao Paulo?

    The required travel and health documents for your Sao Paulo trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Sao Paulo. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Sao Paulo?

Book flights to Sao Paulo if you plan to visit one of these locations
Santos
Guarujá

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to Sao Paulo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Sao Paulo from Iowa.

Can I find flights from Iowa to Sao Paulo with flexible booking policies on momondo?

momondo does allow users to show only those flights to Sao Paulo from Iowa which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Iowa to Sao Paulo?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Sao Paulo from Iowa.

I’m not ready to book a flight from Iowa to Sao Paulo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Iowa to Sao Paulo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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Mon 3/9
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Find better results for your trip to Brazil

Fly into one of these airports located in Sao Paulo

Airports listed have a maximum distance of 48.9 mi from Sao Paulo
Sao Paulo Congonhas Airport
Sao Paulo Guarulhos Intl Airport
Sao Paulo Viracopos Airport