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Cheap flights from Greenville to Los Angeles from $184

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to Los Angeles departing on 3/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Greenville to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
1:55 pm - 10:15 pm
GSP
-
SNA
11h 20m
2 stops
Southwest Logo
11:25 am - 10:40 pm
SNA
-
GSP
8h 15m
2 stops
$414Southwest
Sat, Mar 14 - Tue, Mar 17
United Airlines Logo
4:10 pm - 8:47 pm
GSP
-
SNA
7h 37m
1 stop
United Airlines Logo
6:28 pm - 9:55 am
SNA
-
GSP
12h 27m
2 stops
$425United Airlines
Fri, Apr 3 - Thu, Apr 9
Southwest Logo
6:25 am - 2:35 pm
GSP
-
SNA
11h 10m
2 stops
Southwest Logo
10:25 am - 10:15 pm
SNA
-
GSP
8h 50m
2 stops
$430Southwest
Fri, Apr 3 - Thu, Apr 9
United Airlines Logo
4:15 pm - 10:01 pm
GSP
-
SNA
8h 46m
1 stop
United Airlines Logo
9:14 pm - 10:37 am
SNA
-
GSP
10h 23m
1 stop
$447United Airlines
Mon, Jun 8 - Sat, Jun 13
Delta Logo
11:40 am - 10:38 pm
GSP
-
SNA
13h 58m
2 stops
Delta Logo
2:00 pm - 11:38 pm
SNA
-
GSP
6h 38m
1 stop
$452Delta
Sat, May 23 - Sat, May 30
Southwest Logo
6:25 am - 11:55 am
GSP
-
SNA
8h 30m
2 stops
Southwest Logo
8:35 am - 10:15 pm
SNA
-
GSP
10h 40m
2 stops
$454Southwest
Fri, May 15 - Mon, May 18
United Airlines Logo
4:10 pm - 9:58 pm
GSP
-
SNA
8h 48m
1 stop
United Airlines Logo
9:05 pm - 11:14 am
SNA
-
GSP
11h 09m
1 stop
$456United Airlines
Sun, Apr 26 - Fri, May 1
Delta Logo
11:40 am - 10:38 pm
GSP
-
SNA
13h 58m
2 stops
Delta Logo
5:11 pm - 9:02 am
SNA
-
GSP
12h 51m
2 stops
$458Delta
Wed, May 27 - Wed, Jun 3
American Airlines Logo
6:29 am - 12:05 pm
GSP
-
SNA
8h 36m
1 stop
American Airlines Logo
7:45 am - 6:12 pm
SNA
-
GSP
7h 27m
1 stop
$461American Airlines
Wed, May 27 - Wed, Jun 3
American Airlines Logo
6:29 am - 12:05 pm
GSP
-
SNA
8h 36m
1 stop
American Airlines Logo
7:45 am - 6:12 pm
SNA
-
GSP
7h 27m
1 stop
$462American Airlines
Wed, May 27 - Wed, Jun 3

American Airlines flights from Greenville to Santa Ana

Our best American Airlines deals on Greenville to Santa Ana flight tickets
American Airlines
May 27
GSP6:29 amGreenville
8h 36m
1 stop
SNA12:05 pmSanta Ana J. Wayne/Orange Cnty
Jun 3
SNA7:45 amSanta Ana J. Wayne/Orange Cnty
7h 27m
1 stop
GSP6:12 pmGreenville
$461
American Airlines
May 27
GSP6:29 amGreenville
8h 36m
1 stop
SNA12:05 pmSanta Ana J. Wayne/Orange Cnty
Jun 3
SNA7:45 amSanta Ana J. Wayne/Orange Cnty
7h 27m
1 stop
GSP6:12 pmGreenville
$462
American Airlines
May 27
GSP6:29 amGreenville
8h 36m
1 stop
SNA12:05 pmSanta Ana J. Wayne/Orange Cnty
Jun 3
SNA7:45 amSanta Ana J. Wayne/Orange Cnty
7h 27m
1 stop
GSP6:12 pmGreenville
$463

Delta flights from Greenville to Santa Ana

Our best Delta deals on Greenville to Santa Ana flight tickets
Delta
May 23
GSP11:40 amGreenville
13h 58m
2 stops
SNA10:38 pmSanta Ana J. Wayne/Orange Cnty
May 30
SNA2:00 pmSanta Ana J. Wayne/Orange Cnty
6h 38m
1 stop
GSP11:38 pmGreenville
$452
Delta
May 27
GSP11:40 amGreenville
13h 58m
2 stops
SNA10:38 pmSanta Ana J. Wayne/Orange Cnty
Jun 3
SNA5:11 pmSanta Ana J. Wayne/Orange Cnty
12h 51m
2 stops
GSP9:02 amGreenville
$458
Delta
Apr 8
GSP6:45 amGreenville
7h 59m
1 stop
SNA11:44 amSanta Ana J. Wayne/Orange Cnty
Apr 10
SNA7:05 amSanta Ana J. Wayne/Orange Cnty
11h 47m
2 stops
GSP9:52 pmGreenville
$468

momondo Fare Finder

 
Customize your flight search to find flights from Greenville to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 21, 2026.
Use the filters below to find and compare flights from Greenville to Santa Ana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Sat 3/14

1:55 pm-10:15 pm

2 stops11h 20m

Santa Ana J. Wayne/Orange Cnty

Tue 3/17

11:25 am-10:40 pm

2 stops8h 15m

$414

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Fri 4/3

4:10 pm-8:47 pm

1 stop7h 37m

Santa Ana J. Wayne/Orange Cnty

Thu 4/9

6:28 pm-9:55 am

2 stops12h 27m

$425

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Fri 4/3

6:25 am-2:35 pm

2 stops11h 10m

Santa Ana J. Wayne/Orange Cnty

Thu 4/9

10:25 am-10:15 pm

2 stops8h 50m

$430

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Mon 6/8

4:15 pm-10:01 pm

1 stop8h 46m

Santa Ana J. Wayne/Orange Cnty

Sat 6/13

9:14 pm-10:37 am

1 stop10h 23m

$447

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Sat 5/23

11:40 am-10:38 pm

2 stops13h 58m

Santa Ana J. Wayne/Orange Cnty

Sat 5/30

2:00 pm-11:38 pm

1 stop6h 38m

$452

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Fri 5/15

6:25 am-11:55 am

2 stops8h 30m

Santa Ana J. Wayne/Orange Cnty

Mon 5/18

8:35 am-10:15 pm

2 stops10h 40m

$454

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Sun 4/26

4:10 pm-9:58 pm

1 stop8h 48m

Santa Ana J. Wayne/Orange Cnty

Fri 5/1

9:05 pm-11:14 am

1 stop11h 09m

$456

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Wed 5/27

11:40 am-10:38 pm

2 stops13h 58m

Santa Ana J. Wayne/Orange Cnty

Wed 6/3

5:11 pm-9:02 am

2 stops12h 51m

$458

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Wed 5/27

6:29 am-12:05 pm

1 stop8h 36m

Santa Ana J. Wayne/Orange Cnty

Wed 6/3

7:45 am-6:12 pm

1 stop7h 27m

$461

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Wed 5/27

6:29 am-12:05 pm

1 stop8h 36m

Santa Ana J. Wayne/Orange Cnty

Wed 6/3

7:45 am-6:12 pm

1 stop7h 27m

$462

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Los Angeles from

How to get the cheapest flight ticket from Greenville to Santa Ana

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana?

The cheapest month to fly to Santa Ana from Greenville is in September. Flight prices, which tend to average around $352, are often lower during this time because this is during the off-season. The month of October is another great option to travel to Santa Ana, with average flight prices from Greenville averaging around $391.

How far in advance should I book a flight to Santa Ana?

You are more likely to see cheaper flights to Santa Ana from Greenville when booking weeks ahead of your departure date. In general, you can expect to find flights to Santa Ana for around $509 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santa Ana from Greenville for as low as $353 on momondo.

How have Greenville to Santa Ana flight prices changed over time?

As of February 2026, prices for Greenville to Santa Ana flights are approximately 69% more expensive when compared to flights at the same time last year.

When to book flights from Greenville to Santa Ana

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to Santa Ana according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to Santa Ana (GSP to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Santa Ana

Fastest flight time

6h 55m

Direct flights

None
The fastest flight from Greenville to Santa Ana takes 6h 55m
There are no direct flights from Greenville to Santa Ana. There are no popular flight routes from Greenville to Santa Ana.
Search flight deals

  • How far is Greenville to Santa Ana J. Wayne/Orange Cnty by plane?

    A flight from Greenville to Santa Ana J. Wayne/Orange Cnty will travel around 2014.2 mi. By plane, this route typically takes 6h 55m.

  • When did momondo last update prices for flights from Greenville Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Greenville Airport to Santa Ana J. Wayne/Orange Cnty Airport are updated daily.

  • How many operators does momondo search for flights from Greenville Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Greenville Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Greenville Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The travel and health documents you'll need for your trip to Santa Ana J. Wayne/Orange Cnty Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santa Ana J. Wayne/Orange Cnty Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Greenville to Santa Ana?

Best airlines flying from Greenville to Santa Ana

Compare and see reviews for airlines that fly from Greenville to Santa Ana with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $206Free CancellationRating
7.4
9,335 reviews
Search United Airlines flights
DeltaPriceFrom $296Free CancellationRating
7.9
8,228 reviews
Search Delta flights
American AirlinesPriceFrom $318Free CancellationRating
7.2
11,334 reviews
Search American Airlines flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Santa Ana?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Greenville to Santa Ana. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Greenville to Santa Ana with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santa Ana from Greenville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Greenville to Santa Ana?

momondo helps you find the best flight between Greenville and Santa Ana by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Greenville to Santa Ana right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Greenville to Santa Ana now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santa Ana and let you know when they change.

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