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Cheap flights from Greenville to Los Angeles from $149

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to Los Angeles departing on 9/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Greenville to Los Angeles

Cheap round-trip flights

Southwest Logo
9:30 am - 6:30 pmGSP-SNA
12h 00m2 stops
Southwest Logo
6:55 pm - 9:50 amSNA-GSP
11h 55m2 stops
$245Southwest
Find Deal
Tue, Sep 9 - Tue, Sep 23
American Airlines Logo
7:15 am - 11:57 amGSP-SNA
7h 42m1 stop
American Airlines Logo
6:45 am - 4:57 pmSNA-GSP
7h 12m1 stop
$275American Airlines
Find Deal
Wed, Sep 17 - Sat, Sep 20
American Airlines Logo
8:05 am - 3:45 pmGSP-SNA
10h 40m2 stops
American Airlines Logo
12:47 pm - 10:30 pmSNA-GSP
6h 43m1 stop
$280American Airlines
Find Deal
Wed, Sep 17 - Sat, Sep 20
American Airlines Logo
8:05 am - 3:45 pmGSP-SNA
10h 40m2 stops
American Airlines Logo
9:15 am - 10:58 pmSNA-GSP
10h 43m2 stops
$285American Airlines
Find Deal
Wed, Sep 17 - Sat, Sep 20
Delta Logo
5:30 am - 4:03 pmGSP-SNA
13h 33m2 stops
Delta Logo
8:00 am - 11:34 pmSNA-GSP
12h 34m2 stops
$307Delta
Find Deal
Thu, Sep 4 - Sat, Sep 13
Delta Logo
7:05 am - 6:05 pmGSP-SNA
14h 00m2 stops
Delta Logo
9:20 pm - 9:21 amSNA-GSP
9h 01m1 stop
$329Delta
Find Deal
Wed, Sep 3 - Sun, Sep 7
Southwest Logo
10:20 am - 7:35 pmGSP-SNA
12h 15m2 stops
Southwest Logo
7:45 pm - 9:45 amSNA-GSP
11h 00m2 stops
$341Southwest
Find Deal
Mon, Nov 10 - Sat, Nov 15
United Airlines Logo
12:34 pm - 8:42 pmGSP-SNA
11h 08m2 stops
United Airlines Logo
6:35 pm - 8:51 amSNA-GSP
11h 16m2 stops
$349United Airlines
Find Deal
Wed, Sep 3 - Sun, Sep 7
United Airlines Logo
6:08 am - 8:28 pmGSP-SNA
17h 20m3 stops
United Airlines Logo
8:40 am - 10:46 pmSNA-GSP
11h 06m2 stops
$390United Airlines
Find Deal
Tue, Sep 9 - Tue, Sep 23
Alaska Airlines Logo
11:26 am - 9:42 pmGSP-SNA
13h 16m2 stops
Alaska Airlines Logo
6:45 am - 9:59 pmSNA-GSP
12h 14m2 stops
$567Alaska Airlines
Find Deal
Wed, Sep 24 - Sat, Sep 27

American Airlines flights from Greenville to Santa Ana

Our best American Airlines deals on Greenville to Santa Ana flight tickets
American Airlines
Sep 17
GSP7:15 amGreenville
7h 42m
1 stop
SNA11:57 amSanta Ana J. Wayne/Orange Cnty
Sep 20
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
7h 12m
1 stop
GSP4:57 pmGreenville
$275
Find similar
American Airlines
Sep 17
GSP8:05 amGreenville
10h 40m
2 stops
SNA3:45 pmSanta Ana J. Wayne/Orange Cnty
Sep 20
SNA12:47 pmSanta Ana J. Wayne/Orange Cnty
6h 43m
1 stop
GSP10:30 pmGreenville
$280
Find similar
American Airlines
Sep 17
GSP8:05 amGreenville
10h 40m
2 stops
SNA3:45 pmSanta Ana J. Wayne/Orange Cnty
Sep 20
SNA9:15 amSanta Ana J. Wayne/Orange Cnty
10h 43m
2 stops
GSP10:58 pmGreenville
$285
Find similar

Southwest flights from Greenville to Santa Ana

Our best Southwest deals on Greenville to Santa Ana flight tickets
Southwest
Sep 9
GSP9:30 amGreenville
12h 00m
2 stops
SNA6:30 pmSanta Ana J. Wayne/Orange Cnty
Sep 23
SNA6:55 pmSanta Ana J. Wayne/Orange Cnty
11h 55m
2 stops
GSP9:50 amGreenville
$245
Find similar
Southwest
Nov 10
GSP10:20 amGreenville
12h 15m
2 stops
SNA7:35 pmSanta Ana J. Wayne/Orange Cnty
Nov 15
SNA7:45 pmSanta Ana J. Wayne/Orange Cnty
11h 00m
2 stops
GSP9:45 amGreenville
$341
Find similar
Southwest
Sep 3
GSP9:30 amGreenville
12h 00m
2 stops
SNA6:30 pmSanta Ana J. Wayne/Orange Cnty
Sep 7
SNA7:40 pmSanta Ana J. Wayne/Orange Cnty
11h 15m
2 stops
GSP9:55 amGreenville
$385
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Greenville to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 6, 2025.
Use the filters below to find and compare flights from Greenville to Santa Ana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Tue 9/9

9:30 am-6:30 pm

2 stops12h 00m

Santa Ana J. Wayne/Orange Cnty

Tue 9/23

6:55 pm-9:50 am

2 stops11h 55m

$245

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Wed 9/17

7:15 am-11:57 am

1 stop7h 42m

Santa Ana J. Wayne/Orange Cnty

Sat 9/20

6:45 am-4:57 pm

1 stop7h 12m

$275

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Wed 9/17

8:05 am-3:45 pm

2 stops10h 40m

Santa Ana J. Wayne/Orange Cnty

Sat 9/20

12:47 pm-10:30 pm

1 stop6h 43m

$280

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Wed 9/17

8:05 am-3:45 pm

2 stops10h 40m

Santa Ana J. Wayne/Orange Cnty

Sat 9/20

9:15 am-10:58 pm

2 stops10h 43m

$285

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Thu 9/4

5:30 am-4:03 pm

2 stops13h 33m

Santa Ana J. Wayne/Orange Cnty

Sat 9/13

8:00 am-11:34 pm

2 stops12h 34m

$307

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Wed 9/3

7:05 am-6:05 pm

2 stops14h 00m

Santa Ana J. Wayne/Orange Cnty

Sun 9/7

9:20 pm-9:21 am

1 stop9h 01m

$329

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Mon 11/10

10:20 am-7:35 pm

2 stops12h 15m

Santa Ana J. Wayne/Orange Cnty

Sat 11/15

7:45 pm-9:45 am

2 stops11h 00m

$341

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Wed 9/3

12:34 pm-8:42 pm

2 stops11h 08m

Santa Ana J. Wayne/Orange Cnty

Sun 9/7

6:35 pm-8:51 am

2 stops11h 16m

$349

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Tue 9/9

6:08 am-8:28 pm

3 stops17h 20m

Santa Ana J. Wayne/Orange Cnty

Tue 9/23

8:40 am-10:46 pm

2 stops11h 06m

$390

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Wed 9/24

11:26 am-9:42 pm

2 stops13h 16m

Santa Ana J. Wayne/Orange Cnty

Sat 9/27

6:45 am-9:59 pm

2 stops12h 14m

$567

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Los Angeles from

How to get the cheapest flight ticket from Greenville to Santa Ana

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana?

The cheapest month to fly to Santa Ana from Greenville is in November. Flight prices, which tend to average around $391, are often lower during this time because this is during the off-season. The month of October is another great option to travel to Santa Ana, with average flight prices from Greenville averaging around $431.

What is the cheapest day to depart on your flight to Santa Ana?

On average, the least expensive day to fly to Santa Ana from Greenville is on a Tuesday. momondo users have found tickets for Tuesday departures for as low as $446. However, this price may fluctuate depending on the airline, the season, and holidays. On the other hand, Monday is the most expensive day to depart from Greenville because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $634.

What is the cheapest time of day to depart on your flight to Santa Ana?

Our data shows that the cheapest Greenville to Santa Ana flights are usually those with departure times at noon. Our users have found flights to Santa Ana at noon for as low as $481. Try not to purchase tickets in the afternoon because they tend to be around $508. Of course, these prices can vary depending on the time of year and what airport you fly to.

How far in advance should I book a flight to Santa Ana?

You are more likely to see cheaper flights to Santa Ana from Greenville when booking weeks ahead of your departure date. In general, you can expect to find flights to Santa Ana for around $504 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santa Ana from Greenville for as low as $354 on momondo.

How have Greenville to Santa Ana flight prices changed over time?

When to book flights from Greenville to Santa Ana

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to Santa Ana according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to Santa Ana (GSP to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Santa Ana

Best Price Found

$149

Fastest flight time

6h 28m

Direct flights

None

Airports in Santa Ana

1 airport
The best one-way flight to Santa Ana from Greenville in the past 72 hours is $149. The best round-trip flight deal from Greenville to Santa Ana found on momondo in the last 72 hours is $245.
The fastest flight from Greenville to Santa Ana takes 6h 28m
There are no direct flights from Greenville to Santa Ana. Popular non-direct route for this connection is Greenville Airport - Santa Ana J. Wayne/Orange Cnty Airport.
There is 1 airport near Santa Ana: Santa Ana J. Wayne/Orange Cnty (SNA)
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  • How far is Greenville to Santa Ana J. Wayne/Orange Cnty by plane?

    A flight from Greenville to Santa Ana J. Wayne/Orange Cnty will travel around 2014.2 mi. By plane, this route typically takes 6h 28m.

  • When did momondo last update prices for flights from Greenville Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Greenville Airport to Santa Ana J. Wayne/Orange Cnty Airport are updated daily.

  • How many operators does momondo search for flights from Greenville Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Greenville Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Greenville Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The travel and health documents you'll need for your trip to Santa Ana J. Wayne/Orange Cnty Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santa Ana J. Wayne/Orange Cnty Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Greenville to Santa Ana?

Best airlines flying from Greenville to Santa Ana

Compare and see reviews for airlines that fly from Greenville to Santa Ana with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $296Free CancellationRating
8.0
7,985 reviews
Search Delta flights
American AirlinesPriceFrom $321Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
SouthwestPriceFrom $437Free CancellationRating
8.0
4,244 reviews
Search Southwest flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Santa Ana?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Greenville to Santa Ana. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Greenville to Santa Ana with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santa Ana from Greenville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Greenville to Santa Ana?

momondo helps you find the best flight between Greenville and Santa Ana by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Greenville to Santa Ana right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Greenville to Santa Ana now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santa Ana and let you know when they change.

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