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Cheap flights from Greenville to Los Angeles from $171

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to Los Angeles departing on 11/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

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Multiple Airlines Logo
3:00 pm - 10:23 pmGSP-SNA
10h 23m2 stops
Multiple Airlines Logo
8:19 pm - 4:48 pmSNA-GSP
17h 29m3 stops
$281Multiple Airlines
Find Deal
Fri, Dec 12 - Mon, Dec 15
United Airlines Logo
6:49 am - 11:21 amGSP-SNA
7h 32m1 stop
United Airlines Logo
10:51 am - 8:47 pmSNA-GSP
6h 56m1 stop
$363United Airlines
Find Deal
Wed, Jan 14 - Sat, Jan 17
Delta Logo
6:45 am - 11:35 amGSP-SNA
7h 50m1 stop
Delta Logo
11:46 am - 9:42 pmSNA-GSP
6h 56m1 stop
$367Delta
Find Deal
Tue, Dec 9 - Tue, Dec 16
United Airlines Logo
4:50 pm - 9:52 pmGSP-SNA
8h 02m1 stop
United Airlines Logo
9:00 am - 8:47 pmSNA-GSP
8h 47m2 stops
$368United Airlines
Find Deal
Wed, Jan 14 - Sat, Jan 17
Delta Logo
5:35 am - 11:35 amGSP-SNA
9h 00m1 stop
Delta Logo
5:20 pm - 9:02 amSNA-GSP
12h 42m2 stops
$372Delta
Find Deal
Tue, Dec 9 - Tue, Dec 16
United Airlines Logo
2:55 pm - 10:24 pmGSP-SNA
10h 29m2 stops
United Airlines Logo
9:00 am - 8:47 pmSNA-GSP
8h 47m2 stops
$373United Airlines
Find Deal
Wed, Jan 14 - Sat, Jan 17
Delta Logo
10:08 am - 10:21 pmGSP-SNA
15h 13m2 stops
Delta Logo
6:45 am - 9:42 pmSNA-GSP
11h 57m2 stops
$377Delta
Find Deal
Tue, Dec 9 - Tue, Dec 16
Delta Logo
5:35 am - 2:15 pmGSP-SNA
11h 40m2 stops
Delta Logo
12:45 pm - 11:41 pmSNA-GSP
7h 56m1 stop
$382Delta
Find Deal
Sat, Dec 6 - Sat, Dec 13
American Airlines Logo
6:50 am - 2:09 pmGSP-SNA
10h 19m2 stops
American Airlines Logo
12:28 pm - 12:18 amSNA-GSP
8h 50m2 stops
$387American Airlines
Find Deal
Sat, Dec 6 - Sat, Dec 13
Multiple Airlines Logo
3:00 pm - 10:23 pmGSP-SNA
10h 23m2 stops
Multiple Airlines Logo
11:39 am - 2:10 pmSNA-GSP
23h 31m3 stops
$390Multiple Airlines
Find Deal
Fri, Dec 12 - Sun, Dec 14

United Airlines flights from Greenville to Santa Ana, California

Our best United Airlines deals on Greenville to Santa Ana, California flight tickets
United Airlines
Jan 14
GSP6:49 amGreenville
7h 32m
1 stop
SNA11:21 amSanta Ana J. Wayne/Orange Cnty
Jan 17
SNA10:51 amSanta Ana J. Wayne/Orange Cnty
6h 56m
1 stop
GSP8:47 pmGreenville
$363
Find similar
United Airlines
Jan 14
GSP4:50 pmGreenville
8h 02m
1 stop
SNA9:52 pmSanta Ana J. Wayne/Orange Cnty
Jan 17
SNA9:00 amSanta Ana J. Wayne/Orange Cnty
8h 47m
2 stops
GSP8:47 pmGreenville
$368
Find similar
United Airlines
Jan 14
GSP2:55 pmGreenville
10h 29m
2 stops
SNA10:24 pmSanta Ana J. Wayne/Orange Cnty
Jan 17
SNA9:00 amSanta Ana J. Wayne/Orange Cnty
8h 47m
2 stops
GSP8:47 pmGreenville
$373
Find similar

Southwest flights from Greenville to Santa Ana, California

Our best Southwest deals on Greenville to Santa Ana, California flight tickets
Southwest
Feb 4
GSP11:15 amGreenville
8h 25m
2 stops
SNA4:40 pmSanta Ana J. Wayne/Orange Cnty
Feb 6
SNA5:25 pmSanta Ana J. Wayne/Orange Cnty
13h 45m
2 stops
GSP10:10 amGreenville
$417
Find similar
Southwest
Dec 11
GSP3:05 pmGreenville
9h 10m
2 stops
SNA9:15 pmSanta Ana J. Wayne/Orange Cnty
Dec 20
SNA8:25 pmSanta Ana J. Wayne/Orange Cnty
10h 40m
2 stops
GSP10:05 amGreenville
$492
Find similar
Southwest
Dec 11
GSP3:05 pmGreenville
9h 10m
2 stops
SNA9:15 pmSanta Ana J. Wayne/Orange Cnty
Dec 20
SNA8:25 pmSanta Ana J. Wayne/Orange Cnty
10h 40m
2 stops
GSP10:05 amGreenville
$519
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Greenville to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Greenville to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Fri 12/12

3:00 pm-10:23 pm

2 stops10h 23m

Santa Ana J. Wayne/Orange Cnty

Mon 12/15

8:19 pm-4:48 pm

3 stops17h 29m

$281

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Wed 1/14

6:49 am-11:21 am

1 stop7h 32m

Santa Ana J. Wayne/Orange Cnty

Sat 1/17

10:51 am-8:47 pm

1 stop6h 56m

$363

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Tue 12/9

6:45 am-11:35 am

1 stop7h 50m

Santa Ana J. Wayne/Orange Cnty

Tue 12/16

11:46 am-9:42 pm

1 stop6h 56m

$367

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Wed 1/14

4:50 pm-9:52 pm

1 stop8h 02m

Santa Ana J. Wayne/Orange Cnty

Sat 1/17

9:00 am-8:47 pm

2 stops8h 47m

$368

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Tue 12/9

5:35 am-11:35 am

1 stop9h 00m

Santa Ana J. Wayne/Orange Cnty

Tue 12/16

5:20 pm-9:02 am

2 stops12h 42m

$372

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Wed 1/14

2:55 pm-10:24 pm

2 stops10h 29m

Santa Ana J. Wayne/Orange Cnty

Sat 1/17

9:00 am-8:47 pm

2 stops8h 47m

$373

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Tue 12/9

10:08 am-10:21 pm

2 stops15h 13m

Santa Ana J. Wayne/Orange Cnty

Tue 12/16

6:45 am-9:42 pm

2 stops11h 57m

$377

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Sat 12/6

5:35 am-2:15 pm

2 stops11h 40m

Santa Ana J. Wayne/Orange Cnty

Sat 12/13

12:45 pm-11:41 pm

1 stop7h 56m

$382

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Sat 12/6

6:50 am-2:09 pm

2 stops10h 19m

Santa Ana J. Wayne/Orange Cnty

Sat 12/13

12:28 pm-12:18 am

2 stops8h 50m

$387

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Fri 12/12

3:00 pm-10:23 pm

2 stops10h 23m

Santa Ana J. Wayne/Orange Cnty

Sun 12/14

11:39 am-2:10 pm

3 stops23h 31m

$390

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Greenville to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana, California?

In general, September is the cheapest month to fly from Greenville to Santa Ana, California. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $352. If you aren’t able to travel during the month of September, then book flights to Santa Ana, California from Greenville during October instead. Flights to Santa Ana, California in October, while not as cheap as those in September, still average around $387.

What is the cheapest day to depart on your flight to Santa Ana, California?

The cheapest day to depart from Greenville to Santa Ana, California is on a Tuesday. Travelers who choose to depart for Santa Ana, California on a Tuesday will often find tickets for as low as $446. The most expensive day to fly to Santa Ana, California is Monday, with ticket prices averaging around $634.

What is the cheapest time of day to depart on your flight to Santa Ana, California?

At noon is the cheapest time of day to fly from Greenville to Santa Ana, California when you can find flight prices for as low as $481. Flying to Santa Ana, California at noon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Santa Ana, California is in the afternoon when prices are around $508.

How far in advance should I book a flight to Santa Ana, California?

You are more likely to see cheaper flights to Santa Ana, California from Greenville when booking weeks ahead of your departure date. In general, you can expect to find flights to Santa Ana, California for around $462 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santa Ana, California from Greenville for as low as $367 on momondo.

How have Greenville to Santa Ana, California flight prices changed over time?

When to book flights from Greenville to Santa Ana, California

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to Santa Ana, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to Santa Ana, California (GSP to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Santa Ana, California

Direct flights

None
There are no direct flights from Greenville to Santa Ana, California. There are no popular flight routes from Greenville to Santa Ana, California.
Search flight deals

  • How far is Greenville to Santa Ana J. Wayne/Orange Cnty by plane?

    A flight from Greenville to Santa Ana J. Wayne/Orange Cnty will travel around 2014.2 mi. By plane, this route typically takes 7h 23m.

  • When did momondo last update prices for flights from Greenville Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Greenville Airport to Santa Ana J. Wayne/Orange Cnty Airport are updated daily.

  • How many operators does momondo search for flights from Greenville Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Greenville Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Greenville Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The travel and health documents you'll need for your trip to Santa Ana J. Wayne/Orange Cnty Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santa Ana J. Wayne/Orange Cnty Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Greenville to Santa Ana, California?

Best airlines flying from Greenville to Santa Ana, California

Compare and see reviews for airlines that fly from Greenville to Santa Ana, California with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $296Free CancellationRating
7.9
8,007 reviews
Search Delta flights
American AirlinesPriceFrom $318Free CancellationRating
7.2
11,051 reviews
Search American Airlines flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Santa Ana?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Greenville to Santa Ana. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Greenville to Santa Ana with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santa Ana from Greenville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Greenville to Santa Ana?

momondo helps you find the best flight between Greenville and Santa Ana by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Greenville to Santa Ana right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Greenville to Santa Ana now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santa Ana and let you know when they change.

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