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Cheap flights from Des Moines to McAllen from $164

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to McAllen departing on 3/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Des Moines to McAllen

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:08 pm - 11:06 pm
DSM
-
MFE
4h 58m
1 stop
American Airlines Logo
5:28 am - 10:34 am
MFE
-
DSM
5h 06m
1 stop
$271American Airlines
Wed, Feb 18 - Tue, Feb 24
American Airlines Logo
6:08 pm - 11:06 pm
DSM
-
MFE
4h 58m
1 stop
American Airlines Logo
5:28 am - 10:34 am
MFE
-
DSM
5h 06m
1 stop
$275American Airlines
Wed, Feb 18 - Mon, Feb 23
American Airlines Logo
6:08 pm - 11:06 pm
DSM
-
MFE
4h 58m
1 stop
American Airlines Logo
5:28 am - 1:04 pm
MFE
-
DSM
7h 36m
2 stops
$276American Airlines
Wed, Feb 18 - Tue, Feb 24
American Airlines Logo
6:08 pm - 11:06 pm
DSM
-
MFE
4h 58m
1 stop
American Airlines Logo
5:28 am - 10:34 am
MFE
-
DSM
5h 06m
1 stop
$279American Airlines
Wed, Feb 18 - Mon, Feb 23
American Airlines Logo
6:08 pm - 11:06 pm
DSM
-
MFE
4h 58m
1 stop
American Airlines Logo
5:28 am - 1:04 pm
MFE
-
DSM
7h 36m
2 stops
$280American Airlines
Wed, Feb 18 - Tue, Feb 24
Delta Logo
12:25 pm - 11:57 pm
DSM
-
MFE
11h 32m
2 stops
Delta Logo
5:25 am - 3:42 pm
MFE
-
DSM
10h 17m
2 stops
$282Delta
Tue, Mar 3 - Tue, Mar 10
Delta Logo
10:36 am - 11:57 pm
DSM
-
MFE
13h 21m
2 stops
Delta Logo
5:25 am - 3:42 pm
MFE
-
DSM
10h 17m
2 stops
$286Delta
Fri, Mar 6 - Tue, Mar 10
American Airlines Logo
5:05 am - 10:15 am
DSM
-
MFE
5h 10m
1 stop
American Airlines Logo
5:28 am - 10:44 am
MFE
-
DSM
5h 16m
1 stop
$306American Airlines
Tue, Mar 24 - Sat, Mar 28
United Airlines Logo
8:20 am - 4:07 pm
DSM
-
MFE
7h 47m
1 stop
United Airlines Logo
5:25 pm - 10:30 pm
MFE
-
DSM
5h 05m
1 stop
$309United Airlines
Wed, Feb 4 - Sun, Feb 8
United Airlines Logo
8:00 am - 4:07 pm
DSM
-
MFE
8h 07m
2 stops
United Airlines Logo
5:25 pm - 10:30 pm
MFE
-
DSM
5h 05m
1 stop
$314United Airlines
Wed, Feb 4 - Sun, Feb 8

American Airlines flights from Des Moines to McAllen

Our best American Airlines deals on Des Moines to McAllen flight tickets
American Airlines
Feb 18
DSM6:08 pmDes Moines
4h 58m
1 stop
MFE11:06 pmMcAllen Miller Intl
Feb 24
MFE5:28 amMcAllen Miller Intl
5h 06m
1 stop
DSM10:34 amDes Moines
$271
American Airlines
Feb 18
DSM6:08 pmDes Moines
4h 58m
1 stop
MFE11:06 pmMcAllen Miller Intl
Feb 23
MFE5:28 amMcAllen Miller Intl
5h 06m
1 stop
DSM10:34 amDes Moines
$275
American Airlines
Feb 18
DSM6:08 pmDes Moines
4h 58m
1 stop
MFE11:06 pmMcAllen Miller Intl
Feb 24
MFE5:28 amMcAllen Miller Intl
7h 36m
2 stops
DSM1:04 pmDes Moines
$276

Delta flights from Des Moines to McAllen

Our best Delta deals on Des Moines to McAllen flight tickets
Delta
Mar 3
DSM12:25 pmDes Moines
11h 32m
2 stops
MFE11:57 pmMcAllen Miller Intl
Mar 10
MFE5:25 amMcAllen Miller Intl
10h 17m
2 stops
DSM3:42 pmDes Moines
$282
Delta
Mar 6
DSM10:36 amDes Moines
13h 21m
2 stops
MFE11:57 pmMcAllen Miller Intl
Mar 10
MFE5:25 amMcAllen Miller Intl
10h 17m
2 stops
DSM3:42 pmDes Moines
$286
Delta
Feb 20
DSM10:37 amDes Moines
13h 20m
2 stops
MFE11:57 pmMcAllen Miller Intl
Mar 4
MFE5:28 amMcAllen Miller Intl
10h 12m
2 stops
DSM3:40 pmDes Moines
$336

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to McAllen that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 22, 2026.
Use the filters below to find and compare flights from Des Moines to McAllen that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Wed 2/18

6:08 pm-11:06 pm

1 stop4h 58m

McAllen Miller Intl

Tue 2/24

5:28 am-10:34 am

1 stop5h 06m

$271

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Wed 2/18

6:08 pm-11:06 pm

1 stop4h 58m

McAllen Miller Intl

Mon 2/23

5:28 am-10:34 am

1 stop5h 06m

$275

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Wed 2/18

6:08 pm-11:06 pm

1 stop4h 58m

McAllen Miller Intl

Tue 2/24

5:28 am-1:04 pm

2 stops7h 36m

$276

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Wed 2/18

6:08 pm-11:06 pm

1 stop4h 58m

McAllen Miller Intl

Mon 2/23

5:28 am-10:34 am

1 stop5h 06m

$279

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Wed 2/18

6:08 pm-11:06 pm

1 stop4h 58m

McAllen Miller Intl

Tue 2/24

5:28 am-1:04 pm

2 stops7h 36m

$280

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Tue 3/3

12:25 pm-11:57 pm

2 stops11h 32m

McAllen Miller Intl

Tue 3/10

5:25 am-3:42 pm

2 stops10h 17m

$282

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Fri 3/6

10:36 am-11:57 pm

2 stops13h 21m

McAllen Miller Intl

Tue 3/10

5:25 am-3:42 pm

2 stops10h 17m

$286

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Tue 3/24

5:05 am-10:15 am

1 stop5h 10m

McAllen Miller Intl

Sat 3/28

5:28 am-10:44 am

1 stop5h 16m

$306

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Wed 2/4

8:20 am-4:07 pm

1 stop7h 47m

McAllen Miller Intl

Sun 2/8

5:25 pm-10:30 pm

1 stop5h 05m

$309

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Wed 2/4

8:00 am-4:07 pm

2 stops8h 07m

McAllen Miller Intl

Sun 2/8

5:25 pm-10:30 pm

1 stop5h 05m

$314

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to McAllen from

How to get the cheapest flight ticket from Des Moines to McAllen

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Des Moines to McAllen flights?

You could potentially save up to 61% on your flight if you consider stops on a Des Moines to McAllen flight.

How have Des Moines to McAllen flight prices changed over time?

When to book flights from Des Moines to McAllen

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to McAllen according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to McAllen (DSM to MFE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to McAllen

Fastest flight time

4h 51m

Direct flights

None
The fastest flight from Des Moines to McAllen takes 4h 51m
There are no direct flights from Des Moines to McAllen. There are no popular flight routes from Des Moines to McAllen.
Search flight deals

  • How far is Des Moines to McAllen Miller Intl by plane?

    There are 1093.9 mi between Des Moines and McAllen Miller Intl. 4h 51m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to McAllen Miller Intl Airport?

    Prices for flights from Des Moines Airport to McAllen Miller Intl Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to McAllen Miller Intl Airport?

  • How old do you have to be to fly from Des Moines Airport to McAllen Miller Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to McAllen Miller Intl Airport.

  • What documentation or ID do you need to fly to McAllen Miller Intl Airport?

    The travel and health documents you'll need for your trip to McAllen Miller Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at McAllen Miller Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to McAllen?

Best airlines flying from Des Moines to McAllen

Compare and see reviews for airlines that fly from Des Moines to McAllen with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $258Free CancellationRating
7.2
11,174 reviews
Search American Airlines flights
United AirlinesPriceFrom $283Free CancellationRating
7.4
9,190 reviews
Search United Airlines flights

Traveling to a place near McAllen?

Book flights to McAllen if you plan to visit one of these locations
Weslaco
Pharr
Mission
Edinburg

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to McAllen?

Finding the right flight to McAllen from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to McAllen quick and easy, saving you time and money.

Can I find flights from Des Moines to McAllen with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Des Moines to McAllen flights to just show those with flexible booking policies.

How can momondo help me find flights from Des Moines to McAllen?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Des Moines to McAllen.

I’m not ready to book a flight from Des Moines to McAllen right now. Can momondo alert me if prices change?

If you are simply researching potential flights to McAllen, momondo offers a useful price alert feature which will track prices for flights to McAllen from Des Moines and alert you when they change.

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