Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Des Moines to McAllen from $168

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to McAllen departing on 4/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Des Moines to McAllen

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:00 am - 12:29 pm
DSM
-
MFE
7h 29m
1 stop
American Airlines Logo
7:32 pm - 11:59 pm
MFE
-
DSM
4h 27m
1 stop
$311American Airlines
Tue, Apr 21 - Sat, Apr 25
United Airlines Logo
3:04 pm - 10:59 pm
DSM
-
MFE
7h 55m
1 stop
United Airlines Logo
7:00 am - 4:15 pm
MFE
-
DSM
9h 15m
2 stops
$316United Airlines
Tue, Apr 21 - Sat, Apr 25
Delta Logo
7:00 am - 4:43 pm
DSM
-
MFE
9h 43m
2 stops
Delta Logo
5:25 am - 3:41 pm
MFE
-
DSM
10h 16m
2 stops
$321Delta
Tue, Apr 21 - Sat, Apr 25
American Airlines Logo
7:13 pm - 12:15 am
DSM
-
MFE
5h 02m
1 stop
American Airlines Logo
1:42 pm - 11:59 pm
MFE
-
DSM
10h 17m
2 stops
$372American Airlines
Tue, Jul 7 - Tue, Jul 28
United Airlines Logo
3:04 pm - 9:48 pm
DSM
-
MFE
6h 44m
1 stop
United Airlines Logo
5:15 pm - 10:43 pm
MFE
-
DSM
5h 28m
1 stop
$391United Airlines
Tue, Apr 21 - Sat, Apr 25
American Airlines Logo
7:02 pm - 12:20 am
DSM
-
MFE
5h 18m
1 stop
American Airlines Logo
10:39 am - 4:03 pm
MFE
-
DSM
5h 24m
1 stop
$393American Airlines
Tue, Jun 16 - Sat, Jun 20
United Airlines Logo
3:04 pm - 10:59 pm
DSM
-
MFE
7h 55m
1 stop
United Airlines Logo
5:17 am - 4:15 pm
MFE
-
DSM
10h 58m
2 stops
$396United Airlines
Tue, Apr 21 - Sat, Apr 25
United Airlines Logo
1:10 pm - 10:59 pm
DSM
-
MFE
9h 49m
2 stops
United Airlines Logo
7:00 am - 4:15 pm
MFE
-
DSM
9h 15m
2 stops
$401United Airlines
Tue, Apr 21 - Sat, Apr 25
American Airlines Logo
7:02 pm - 12:20 am
DSM
-
MFE
5h 18m
1 stop
American Airlines Logo
1:35 pm - 12:12 am
MFE
-
DSM
10h 37m
2 stops
$423American Airlines
Tue, Jun 16 - Sat, Jun 20
Delta Logo
5:45 am - 4:43 pm
DSM
-
MFE
10h 58m
2 stops
Delta Logo
1:03 pm - 10:34 pm
MFE
-
DSM
9h 31m
2 stops
$430Delta
Sun, Apr 19 - Sun, Apr 26

American Airlines flights from Des Moines to McAllen

Our best American Airlines deals on Des Moines to McAllen flight tickets
American Airlines
Apr 21
DSM5:00 amDes Moines
7h 29m
1 stop
MFE12:29 pmMcAllen Miller Intl
Apr 25
MFE7:32 pmMcAllen Miller Intl
4h 27m
1 stop
DSM11:59 pmDes Moines
$311
American Airlines
Jul 7
DSM7:13 pmDes Moines
5h 02m
1 stop
MFE12:15 amMcAllen Miller Intl
Jul 28
MFE1:42 pmMcAllen Miller Intl
10h 17m
2 stops
DSM11:59 pmDes Moines
$372
American Airlines
Jun 16
DSM7:02 pmDes Moines
5h 18m
1 stop
MFE12:20 amMcAllen Miller Intl
Jun 20
MFE10:39 amMcAllen Miller Intl
5h 24m
1 stop
DSM4:03 pmDes Moines
$393

United Airlines flights from Des Moines to McAllen

Our best United Airlines deals on Des Moines to McAllen flight tickets
United Airlines
Apr 21
DSM3:04 pmDes Moines
7h 55m
1 stop
MFE10:59 pmMcAllen Miller Intl
Apr 25
MFE7:00 amMcAllen Miller Intl
9h 15m
2 stops
DSM4:15 pmDes Moines
$316
United Airlines
Apr 21
DSM3:04 pmDes Moines
6h 44m
1 stop
MFE9:48 pmMcAllen Miller Intl
Apr 25
MFE5:15 pmMcAllen Miller Intl
5h 28m
1 stop
DSM10:43 pmDes Moines
$391
United Airlines
Apr 21
DSM3:04 pmDes Moines
7h 55m
1 stop
MFE10:59 pmMcAllen Miller Intl
Apr 25
MFE5:17 amMcAllen Miller Intl
10h 58m
2 stops
DSM4:15 pmDes Moines
$396

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to McAllen that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Des Moines to McAllen that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Tue 4/21

5:00 am-12:29 pm

1 stop7h 29m

McAllen Miller Intl

Sat 4/25

7:32 pm-11:59 pm

1 stop4h 27m

$311

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Tue 4/21

3:04 pm-10:59 pm

1 stop7h 55m

McAllen Miller Intl

Sat 4/25

7:00 am-4:15 pm

2 stops9h 15m

$316

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Tue 4/21

7:00 am-4:43 pm

2 stops9h 43m

McAllen Miller Intl

Sat 4/25

5:25 am-3:41 pm

2 stops10h 16m

$321

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Tue 7/7

7:13 pm-12:15 am

1 stop5h 02m

McAllen Miller Intl

Tue 7/28

1:42 pm-11:59 pm

2 stops10h 17m

$372

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Tue 4/21

3:04 pm-9:48 pm

1 stop6h 44m

McAllen Miller Intl

Sat 4/25

5:15 pm-10:43 pm

1 stop5h 28m

$391
Quickest round-trip

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Tue 6/16

7:02 pm-12:20 am

1 stop5h 18m

McAllen Miller Intl

Sat 6/20

10:39 am-4:03 pm

1 stop5h 24m

$393

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Tue 4/21

3:04 pm-10:59 pm

1 stop7h 55m

McAllen Miller Intl

Sat 4/25

5:17 am-4:15 pm

2 stops10h 58m

$396

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Tue 4/21

1:10 pm-10:59 pm

2 stops9h 49m

McAllen Miller Intl

Sat 4/25

7:00 am-4:15 pm

2 stops9h 15m

$401

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Tue 6/16

7:02 pm-12:20 am

1 stop5h 18m

McAllen Miller Intl

Sat 6/20

1:35 pm-12:12 am

2 stops10h 37m

$423

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Sun 4/19

5:45 am-4:43 pm

2 stops10h 58m

McAllen Miller Intl

Sun 4/26

1:03 pm-10:34 pm

2 stops9h 31m

$430

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to McAllen from

How to get the cheapest flight ticket from Des Moines to McAllen

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Des Moines and McAllen?

How have Des Moines to McAllen flight prices changed over time?

When to book flights from Des Moines to McAllen

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to McAllen according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to McAllen (DSM to MFE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to McAllen

Fastest flight time

6h 50m

Direct flights

None
The fastest flight from Des Moines to McAllen takes 6h 50m
There are no direct flights from Des Moines to McAllen. There are no popular flight routes from Des Moines to McAllen.
Search flight deals

  • How far is Des Moines to McAllen Miller Intl by plane?

    There are 1093.9 mi between Des Moines and McAllen Miller Intl. 6h 50m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to McAllen Miller Intl Airport?

    Prices for flights from Des Moines Airport to McAllen Miller Intl Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to McAllen Miller Intl Airport?

  • How old do you have to be to fly from Des Moines Airport to McAllen Miller Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to McAllen Miller Intl Airport.

  • What documentation or ID do you need to fly to McAllen Miller Intl Airport?

    The travel and health documents you'll need for your trip to McAllen Miller Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at McAllen Miller Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to McAllen?

Best airlines flying from Des Moines to McAllen

Compare and see reviews for airlines that fly from Des Moines to McAllen with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $258Free CancellationRating
7.1
11,489 reviews
Search American Airlines flights
United AirlinesPriceFrom $283Free CancellationRating
7.4
9,460 reviews
Search United Airlines flights

Traveling to a place near McAllen?

Book flights to McAllen if you plan to visit one of these locations
Weslaco
Pharr
Mission
Edinburg

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to McAllen?

Finding the right flight to McAllen from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to McAllen quick and easy, saving you time and money.

Can I find flights from Des Moines to McAllen with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Des Moines to McAllen flights to just show those with flexible booking policies.

How can momondo help me find flights from Des Moines to McAllen?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Des Moines to McAllen.

I’m not ready to book a flight from Des Moines to McAllen right now. Can momondo alert me if prices change?

If you are simply researching potential flights to McAllen, momondo offers a useful price alert feature which will track prices for flights to McAllen from Des Moines and alert you when they change.

An easier way to manage your McAllen trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 4/22
Wed 4/29
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States