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Cheap flights from Des Moines to Medford from $259

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Medford departing on 11/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Des Moines to Medford

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
3:30 pm - 10:50 pmDSM-MFR
9h 20m2 stops
Delta Logo
6:00 am - 5:16 pmMFR-DSM
9h 16m2 stops
$359Delta
Find Deal
sáb., nov. 1 - mar., nov. 4
Delta Logo
3:30 pm - 10:50 pmDSM-MFR
9h 20m2 stops
Delta Logo
6:00 am - 5:16 pmMFR-DSM
9h 16m2 stops
$364Delta
Find Deal
sáb., nov. 1 - mar., nov. 4
United Airlines Logo
5:14 pm - 9:14 pmDSM-MFR
6h 00m1 stop
United Airlines Logo
5:00 am - 12:38 pmMFR-DSM
5h 38m1 stop
$429United Airlines
Find Deal
sáb., nov. 1 - mar., nov. 4
United Airlines Logo
5:14 pm - 9:14 pmDSM-MFR
6h 00m1 stop
United Airlines Logo
5:00 am - 12:38 pmMFR-DSM
5h 38m1 stop
$434United Airlines
Find Deal
sáb., nov. 1 - mar., nov. 4
United Airlines Logo
11:32 am - 8:08 pmDSM-MFR
10h 36m2 stops
United Airlines Logo
5:00 am - 12:38 pmMFR-DSM
5h 38m1 stop
$439United Airlines
Find Deal
sáb., nov. 1 - mar., nov. 4
American Airlines Logo
6:20 pm - 11:04 pmDSM-MFR
6h 44m1 stop
American Airlines Logo
5:20 am - 1:49 pmMFR-DSM
6h 29m1 stop
$593American Airlines
Find Deal
dom., nov. 23 - sáb., nov. 29
Multiple Airlines Logo
7:00 am - 9:01 pmDSM-MFR
16h 01m1 stop
Multiple Airlines Logo
9:53 pm - 4:54 pmMFR-DSM
41h 01m2 stops
$595Multiple Airlines
Find Deal
dom., nov. 23 - sáb., nov. 29
American Airlines Logo
5:10 am - 1:00 pmDSM-MFR
9h 50m1 stop
American Airlines Logo
5:20 am - 1:49 pmMFR-DSM
6h 29m1 stop
$797American Airlines
Find Deal
sáb., nov. 22 - sáb., nov. 29
United Airlines Logo
5:14 pm - 9:14 pmDSM-MFR
6h 00m1 stop
United Airlines Logo
6:00 am - 11:44 pmMFR-DSM
15h 44m2 stops
$896United Airlines
Find Deal
sáb., nov. 22 - sáb., nov. 29
United Airlines Logo
1:05 pm - 10:30 pmDSM-MFR
11h 25m2 stops
United Airlines Logo
6:00 am - 8:40 pmMFR-DSM
12h 40m2 stops
$901United Airlines
Find Deal
dom., nov. 23 - sáb., nov. 29

United Airlines flights from Des Moines to Medford

Our best United Airlines deals on Des Moines to Medford flight tickets
United Airlines
Nov 1
DSM9:01 amDes Moines
6h 22m
1 stop
MFR1:23 pmMedford
Nov 4
MFR5:00 amMedford
5h 38m
1 stop
DSM12:38 pmDes Moines
$429
Find similar
United Airlines
Nov 1
DSM5:14 pmDes Moines
6h 00m
1 stop
MFR9:14 pmMedford
Nov 4
MFR5:00 amMedford
5h 38m
1 stop
DSM12:38 pmDes Moines
$434
Find similar
United Airlines
Nov 1
DSM11:32 amDes Moines
10h 36m
2 stops
MFR8:08 pmMedford
Nov 4
MFR5:00 amMedford
5h 38m
1 stop
DSM12:38 pmDes Moines
$439
Find similar

American Airlines flights from Des Moines to Medford

Our best American Airlines deals on Des Moines to Medford flight tickets
American Airlines
Nov 23
DSM6:20 pmDes Moines
6h 44m
1 stop
MFR11:04 pmMedford
Nov 29
MFR5:20 amMedford
6h 29m
1 stop
DSM1:49 pmDes Moines
$593
Find similar
American Airlines
Oct 23
DSM6:40 pmDes Moines
7h 13m
1 stop
MFR11:53 pmMedford
Oct 25
MFR5:19 amMedford
6h 28m
1 stop
DSM1:47 pmDes Moines
$633
Find similar
American Airlines
Nov 22
DSM5:10 amDes Moines
9h 50m
1 stop
MFR1:00 pmMedford
Nov 29
MFR5:20 amMedford
6h 29m
1 stop
DSM1:49 pmDes Moines
$797
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Medford that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated octubre 22, 2025.
Use the filters below to find and compare flights from Des Moines to Medford that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

sáb. 11/1

3:30 pm-10:50 pm

2 stops9h 20m

Medford

mar. 11/4

6:00 am-5:16 pm

2 stops9h 16m

$359

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

sáb. 11/1

3:30 pm-10:50 pm

2 stops9h 20m

Medford

mar. 11/4

6:00 am-5:16 pm

2 stops9h 16m

$364

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

sáb. 11/1

5:14 pm-9:14 pm

1 stop6h 00m

Medford

mar. 11/4

5:00 am-12:38 pm

1 stop5h 38m

$429

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

sáb. 11/1

5:14 pm-9:14 pm

1 stop6h 00m

Medford

mar. 11/4

5:00 am-12:38 pm

1 stop5h 38m

$434

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

sáb. 11/1

11:32 am-8:08 pm

2 stops10h 36m

Medford

mar. 11/4

5:00 am-12:38 pm

1 stop5h 38m

$439

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

dom. 11/23

6:20 pm-11:04 pm

1 stop6h 44m

Medford

sáb. 11/29

5:20 am-1:49 pm

1 stop6h 29m

$593

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

dom. 11/23

7:00 am-9:01 pm

1 stop16h 01m

Medford

sáb. 11/29

9:53 pm-4:54 pm

2 stops41h 01m

$595

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

sáb. 11/22

5:10 am-1:00 pm

1 stop9h 50m

Medford

sáb. 11/29

5:20 am-1:49 pm

1 stop6h 29m

$797

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

sáb. 11/22

5:14 pm-9:14 pm

1 stop6h 00m

Medford

sáb. 11/29

6:00 am-11:44 pm

2 stops15h 44m

$896

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

dom. 11/23

1:05 pm-10:30 pm

2 stops11h 25m

Medford

sáb. 11/29

6:00 am-8:40 pm

2 stops12h 40m

$901

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
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See travel insights to Medford from

How to get the cheapest flight ticket from Des Moines to Medford

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Medford?

The cheapest day to depart from Des Moines to Medford is on a Friday when prices can be found for as low as $430. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $885. These prices are subject to change though, so be sure to set up a Price Alert for flights to Medford.

What is the cheapest time of day to depart on your flight to Medford?

In the afternoon is the cheapest time of day to fly from Des Moines to Medford when you can find flight prices for as low as $430. Flying to Medford in the afternoon is an ideal time because this is during off-peak travel hours. Flights in the morning are often more expensive with an average ticket price of $548.

When to book flights from Des Moines to Medford

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Medford according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Medford (DSM to MFR) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Medford

Direct flights

None
There are no direct flights from Des Moines to Medford. There are no popular flight routes from Des Moines to Medford.
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  • How far is Des Moines to Medford by plane?

    A flight from Des Moines to Medford will travel around 1495.2 mi. A reasonable flight in good conditions will take 6h 00m.

  • When did momondo last update prices for flights from Des Moines Airport to Medford Airport?

    Prices for flights from Des Moines Airport to Medford Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Medford Airport?

  • How old do you have to be to fly from Des Moines Airport to Medford Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Medford Airport.

  • What documentation or ID do you need to fly to Medford Airport?

    The travel and health documents you'll need for your trip to Medford Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Medford Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Medford?

Best airlines flying from Des Moines to Medford

Compare and see reviews for airlines that fly from Des Moines to Medford with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $268Free CancellationRating
7.2
11,028 reviews
Search American Airlines flights
United AirlinesPriceFrom $274Free CancellationRating
7.4
8,990 reviews
Search United Airlines flights

Traveling to a place near Medford?

Book flights to Medford if you plan to visit one of these locations
Grants Pass
Ashland
Yreka
Canyonville

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Medford?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Medford from Des Moines.

Can I find flights from Des Moines to Medford with flexible booking policies on momondo?

momondo does allow users to show only those flights to Medford from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Medford?

Once you have performed a search for Des Moines to Medford flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Des Moines to Medford right now. Can momondo alert me if prices change?

Price alerts on flights to Medford from Des Moines are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Medford trip

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